Table 2.
CMR data
| Control (n = 31) |
Cardiac amyloidosis (n = 24) |
HCM (n = 21) |
HHD (n = 80) |
p value | |
|---|---|---|---|---|---|
| IVSd, mm | 10 ± 1 | 18 ± 4*‡ | 17 ± 4*‡ | 14 ± 2*† | < 0.0001 |
| LVEDD, mm | 50 ± 4 | 47 ± 5‡ | 47 ± 6‡ | 50 ± 5† | 0.0016 |
| LVEDV index, mL/m2 | 55 ± 8 | 50 ± 11 | 51 ± 10 | 54 ± 15 | 0.42 |
| LVESV index, mL/m2 | 18 ± 5 | 21 ± 8 | 15 ± 7 | 19 ± 9 | 0.15 |
| SV index, mL/m2 | 36 ± 5 | 29 ± 8*†‡ | 37 ± 9 | 35 ± 8 | 0.0026 |
| EF, % | 67 ± 6 | 58 ± 11*†‡ | 71 ± 11 | 66 ± 9 | < 0.0001 |
| LV mass index, g/m2 | 52 ± 11 | 87 ± 22*‡ | 87 ± 29* | 73 ± 17* | < 0.0001 |
| LGE present | 0 | 24 (100%) | 17 (81%) | 29 (36%) | < 0.0001 |
| LGE quantitative, % | 0 | 55 ± 32*†‡ | 10 ± 9 | 3 ± 6 | < 0.0001 |
| Native T1, ms | 1225 ± 21 | 1409 ± 59*†‡ | 1266 ± 44* | 1257 ± 41* | < 0.0001 |
| ECV, % | 26 ± 3 | 51 ± 6*†‡ | 30 ± 6 | 31 ± 6* | < 0.0001 |
Bold values indicate statistically significant p values with p< 0.05
Values are mean ± standard deviation or numbers (%). ECV data available for n = 12 (control), n = 22 (cardiac amyloidosis), n = 14 (HCM), n = 32 (HDD)
HCM hypertrophic cardiomyopathy; HHD hypertensive heart disease; IVSD inter-ventricular septum thickness at end-diastole; EF LV ejection fraction; ECV extracellular volume; LGE late gadolinium enhancement; LV left ventricle; LVEDD LV end-diastolic dimeter; LVEDV LV end-diastolic volume; LVESV LV end-diastolic volume; SV stroke volume
*p < 0.05 vs. control
†p < 0.05 vs. HCM
‡p < 0.05 vs. HHD