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. 2023 Mar 1;58(3):185–195. doi: 10.1007/s00535-022-01954-9

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© The Author(s) 2023

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Fig. 5 — Histological features of early stage (greater curvature of the corpus). a The fundic gland mucosal structure that is almost similar to normal is preserved, although there is the elongation of the gastric pit (ratio of the gastric pit length to the gastric gland length: 1.0:1.8), and there is moderate chronic inflammatory cell infiltration between the fundic glands (stronger in the glandular area than in the gastric pit area). Numerous residual parietal cells exhibit pseudohypertrophy (degenerative swelling and cell protrusion). (HE staining). b Intraglandular hyperplasia of the ECL cells is observed (chromogranin A staining)