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. 2023 Mar 9;13:3950. doi: 10.1038/s41598-023-30926-z

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Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Alternative mRNA splicing associations with AUD by brain region. (A) Volcano plot displaying differentially spliced genes between individuals with AUD and controls for each brain region. (B) Scatter plot showing differential splicing associations across brain regions from differentially spliced genes. Note ΔPSI stands for the change in percent-spliced-in and that each colored dot represents a specific splicing event in a cluster from a significantly differentially spliced gene (p_adj < 0.05).