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. 2023 Mar 9;13:3957. doi: 10.1038/s41598-023-30848-w

Table 4.

ASDAS-CRP and ASDAS-ESR from three consecutive assessments (n = 201).

T1 T2 T3 p-value#
T1 versus T2 T2 versus T3 T1 versus T3
ASDAS-CRP
   (Min, Max) (0.1, 4.1) (0.0, 4.7) (0.1, 4.3) 0.225 0.580 0.058
   Mean ± SD 1.6 ± 0.8 1.5 ± 0.8 1.5 ± 0.8
   Median (P25, P75) 1.5 (0.9, 2.1) 1.3 (0.9, 1.9) 1.4 (0.8, 1.9)
ASDAS-ESR
   (Min, Max) (0.3, 4.4) (0.3, 4.2) (0.4, 4.2) 0.510 0.488 0.161
   Mean ± SD 1.6 ± 0.8 1.5 ± 0.7 1.5 ± 0.7
   Median (P25, P75) 1.4 (1.1, 2.0) 1.5 (1.0, 2.0) 1.4 (1.0, 1.9)

Abbreviations: ASDAS Ankylosing Spondylitis Disease Activity Score, CRP C-reactive protein, ESR erythrocyte sedimentation rate, T time, SD standard deviation, P percentile.

Comorbidities were identified within 1 year before the index date.

#Because the p-value of the normality test (Kolmogorov–Smirnov test) is < 0.05, the Wilcoxon Signed Rank test is used.

Time of the three consecutive assessment: T1: the earliest time was considered the first time; T2: the second time was 84 ± 7 days; T3: the third time was 168 ± 7 days.