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. 2023 Mar 9;13:3971. doi: 10.1038/s41598-023-30756-z

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Activities of cholinesterases. (A) Activities of acetylcholinesterase (AChE) (B) Activities of butyrylcholinesterase (BChE) before (preOP), 15 min after (postOP day 0) and one day after surgery (postOP day 1) compared between patients receiving standard general anaesthesia (Placebo, blue, n = 30) or general anaesthesia combined with perioperative dexmedetomidine (Dex, red, n = 26). The Boxplots show median and IQR (lower and upper hinges). P-values compare values of all three points in time within each group, using the Friedman rank analysis.