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. 2023 Mar 9;13:3971. doi: 10.1038/s41598-023-30756-z

Table 3.

Activities of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) before (preOP), 15 min after (postOP day 0) and one day after surgery (postOP day 1) compared between patients receiving standard general anaesthesia (Placebo, n = 30) or general anaesthesia combined with perioperative dexmedetomidine (Dex, n = 26).

AChE (U/g Hb) preOP postOP day 0 postOP day 1
Placebo 44.80 [40.88; 48.05] 41.35 [33.43; 47.50] 43.05 [38.08; 45.63]
Dex 40.50 [36.78; 54.90] 45.00 [35.93; 53.30] 44.60 [40.23; 49.73]
P-value 0.388 0.194 0.257
BuChE (U/l) preOP postOP day 0 postOP day 1
Placebo 3087.9 [1871.4; 3721.2] 2511.7 [1686.1; 2889.9] 2260.1 [1876.7; 2927.1]
Dex 2511.8 [1766.2; 3418.6] 2074.4 [1436.2; 2618.1] 2474.4 [1701.4; 2874.7]
P-value 0.194 0.293 0.908

Tables show medians with interquartile ranges. P-values compare values at individual points in time between both groups with the Mann–Whitney U test.