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. 2023 Feb 24;14:1149821. doi: 10.3389/fphys.2023.1149821

FIGURE 3.

FIGURE 3

Non-coding RNAs (ncRNAs) involved in epithelial-mesenchymal transition (EMT). This illustration demonstrates that the EMT process is predominantly composed of transforming growth factor-β1 (TGF-β), WNT and neurogenic locus notch homolog protein (NOTCH) signaling pathways. Note: SMAD2,3,4, Mothers against decapentaplegic homolog 2,3,4; GSK3β, glycogen synthase kinase-3β; LEF, Lymphoid enhancer-binding factor; N-cadherin, Neural cadherin; TCF, T cell factor; NOTCH-ICD, intracellular domain of the NOTCH receptor.