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. Author manuscript; available in PMC: 2023 Apr 5.
Published in final edited form as: Behav Brain Res. 2022 Aug 31;436:114087. doi: 10.1016/j.bbr.2022.114087

Figure 2. Acute Alcohol Dose-Response Curve in The Hot Plate Test.

Figure 2.

Antinociception effect of alcohol measured by the hot plate test expressed as %MPE (Maximum possible effect), at different doses, 1, 1.5 and 2 g/kg, 30 min after alcohol gavage in (A) B6 male mice, (B) D2 male mice, (C) B6 female mice and (D) D2 female mice. Values are expressed as mean ± SEM. n= 8/group. Results were compared using one-way ANOVA with treatment as the factor and post-hoc Dunnett’s test (*: p<0.05, ** and p<0.01 vs. vehicle). E) Comparison of the AUC of time-course of antinociceptive effect of alcohol measured by hot plate in all mice (Results were compared using two-way ANOVA with sex and strain as a factor and post-hoc Sidak’s test).