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. 2023 Mar 10;13(12):8043–8048. doi: 10.1039/d3ra00836c

Selected results for the optimal reaction conditionsa.

graphic file with name d3ra00836c-u2.jpg
Entry Product Yieldb (%)
1 graphic file with name d3ra00836c-u3.jpg 92
2 graphic file with name d3ra00836c-u4.jpg 94
3 graphic file with name d3ra00836c-u5.jpg 93
4 graphic file with name d3ra00836c-u6.jpg 93
5 graphic file with name d3ra00836c-u7.jpg 91
6 graphic file with name d3ra00836c-u8.jpg 92
7 graphic file with name d3ra00836c-u9.jpg 93
8 graphic file with name d3ra00836c-u10.jpg 95
9 graphic file with name d3ra00836c-u11.jpg 92
10 graphic file with name d3ra00836c-u12.jpg 91
11 graphic file with name d3ra00836c-u13.jpg 85
12 graphic file with name d3ra00836c-u14.jpg 76
13 graphic file with name d3ra00836c-u15.jpg 87
14 graphic file with name d3ra00836c-u16.jpg 93
15 graphic file with name d3ra00836c-u17.jpg 55
16 graphic file with name d3ra00836c-u18.jpg 91
a

Reaction conditions: ArGeMe31 (0.65 mmol), aldehyde 2 (0.5 mmol), CoI2 (3.9 mg, 2.5 mol%), tmphen (L8, 3.0 mg, 2.5 mol%), K2CO3 (138 mg, 1.0 mmol), THF (3 mL), 65 °C for 12 h, under air in pressure tubes.

b

Yields of isolated products after chromatography.