FIG. 8.

Influenza virus infection induces expression of cytokines that signal via the STAT1 or STAT3 pathway. Pooled RNA from the lungs of five animals (control and infected) was reverse transcribed into cDNA to assess cytokine gene expression in the lung during influenza virus infection. The mRNA levels for cytokines were measured using the 7700 Sequence Detector (see Materials and Methods for details). The y axis indicates the fold increase in mRNA of the cytokines in infected lung compared to that of the uninfected control, and the x axis denotes days of infection. The data presented are the mean of three independent experiment ± SEM.