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. 2023 Mar 10;21:189. doi: 10.1186/s12967-023-04035-4

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© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — Analysis of IMMT at the single-cell level. A–H single-cell analysis. Heatmap showing the IMMT expression profile in immune cells, malignant cells, stromal cells and others of BC based on multiple GEO datasets (A). Uniform Manifold Approximation and Projection (UMAP) plots showing IMMT expression mapping on to different cell types in BC based on the GSE75688 dataset (B and C). Heatmap visualizing the gene signature MITOPHAGY of T cells and BC tumor (D). Communication network among immune cells (E). UMAP plots showing IMMT expression clusters (F–H)