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. 2023 Mar 10;21:189. doi: 10.1186/s12967-023-04035-4

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© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 7 — Involvement of IMMT in cell cycle progression and mitochondrial antioxidant defenses. Genetic and enrichment analyses of TCGA samples were conducted using the LinkedOmics functional modules. Volcano plot showing the PCC and p value of the IMMT-coexpressed genes (A). Heatmap showing top 30 positively (B) and negatively (C) correlated genes with IMMT. Bubble plot showing the normalized enrichment score, involved gene count and false discovery rate (FDR) of the Reactome pathway terms (D). Dot plots showing the correlation between IMMT and Ki67 (E), PCNA (F), and MCM2 (G), CDK4 (H), CDK2 (I) and CDK1 (J), PGC-1β (K), PRDX1(L), PRDX3(M), HSPA9(N), HSPD1(O), and SOD2(P)