Fig. 2.

Diagnostic performance of CSF p-tau235 when discriminating syndromic groups stratified by CSF amyloidosis. Both in a the Paris cohort and b the BIODEGMAR cohort CSF p-tau235 displayed high accuracies differentiating dementia Aβ+ from dementia Aβ− and MCI Aβ+ from MCI Aβ−, similar to CSF p-tau181 and p-tau231, and lower than CSF p-tau217. Data information: forest plots showing AUC values from ROC analysis (CI_95% available in Supplementary Table 4). Comparisons of AUC values between CSF p-tau235 and other available CSF p-tau biomarkers were determined using DeLong test (significance is indicated in bold)