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. 2023 Mar 9;23:96. doi: 10.1186/s12905-023-02219-0

Table 10.

Sensitivity analysis results for a time horizon of 2 years: variation of prevalence and costs

Additional tests** versus Aptima, n =  Additional costs versus Aptima, €
Lower values for costs* (− 25%) and prevalence (10.5%)
Hybrid Capture® 2 265,652 283,277,525.29 €
Cobas® 4800 276,698 2,294,970.33 €
Higher values for costs* (+ 25%) and lower value for prevalence (10.5%)
Hybrid Capture® 2 265,652 442,621,133.27 €
Cobas® 4800 276,698 3,585,891.13 €
Lower values for costs* (− 25%) and higher value for prevalence (25.4%)
Hybrid Capture® 2 243,924 432,074,832.70 €
Cobas® 4800 230,360 1,910,159.13 €
Higher values for costs* (+ 25%) and prevalence (25.4%)
Hybrid Capture® 2 243,924 675,116,926.10 €
Cobas® 4800 230,360 2,984,623.65 €

*Includes cytology, colposcopy, and biopsy

**Includes HPV tests and other diagnostic tests (cytology, colposcopy, and biopsy)

Includes the cost of HPV genotyping after the first and subsequent Hybrid Capture® 2 tests