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. 2023 Mar 9;23:96. doi: 10.1186/s12905-023-02219-0

Table 4.

Additional tests and costs with HC2 and Cobas versus Aptima over 2 years of follow-up

Diagnostic tests* after the first HPV test, n =  Costs, € Additional tests* versus Aptima, n =  Additional costs versus Aptima, €
Aptima® HPV 1,137,309 11,794,860 €
Hybrid Capture® 2 1,399,753 393,354,356.91 €** 262,443 381,559,496.91 €
Cobas® 4800 1,407,165 14,592,550.70 € 269,856 2,797,690.71 €

Legend: Aptima: Aptima® HPV; Cobas: Cobas® 4800; HC2: Hybrid Capture® 2.

*Includes HPV tests and other diagnostic tests (cytology, colposcopy, and biopsy)

**Includes the cost of HPV genotyping after the first and subsequent Hybrid Capture® 2 tests