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. 2023 Mar 9;23:96. doi: 10.1186/s12905-023-02219-0

Table 7.

Additional tests and costs with HC2 and Cobas versus Aptima until the first colposcopy

Diagnostic tests* after the first HPV test, n =  Costs, € Additional tests* versus Aptima, n =  Additional costs versus Aptima, €
Aptima® HPV 786,195 10,626,532.78 €
Hybrid Capture® 2 989,993 392,078,694.14 €** 203,798 381,452,161.36 €
Cobas® 4800 972,460 13,144,973.31 € 186,265 2,518,440.53 €

Legend: Aptima: Aptima® HPV; Cobas: Cobas® 4800; HC2: Hybrid Capture® 2.

*Includes HPV tests and other diagnostic tests (cytology, colposcopy, and biopsy)

**Includes the cost of HPV genotyping after the first and subsequent Hybrid Capture® 2 tests