Table 1.
Dose escalation in Phase Ib.
| Dose level | Dose of ApTOLL (mg/kg) | Number of patients to be enrolled (Ratio ApTOLL: placebo) |
|---|---|---|
| 1 | 0.025 | 8 (6 ApTOLL: 2placebo) |
| 2 | 0.05 | 8 (6 ApTOLL: 2placebo) |
| 3 | 0.1 | 8 (6 ApTOLL: 2placebo) |
| 4 | 0.2 | 8 (6 ApTOLL: 2placebo) |
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