;;Ki (µM);Ki (µM);Ki (µM);Ki (µM);kinact/KI (M-1s-1);kinact/KI (M-1s-1);kinact/KI (M-1s-1);kinact/KI (M-1s-1)
#;;cathepsin B;cathepsin S;cathepsin L;cathepsin K;cathepsin B;cathepsin S;cathepsin L;cathepsin K
1a;OC(C1=CC(COC[C@H](NC([C@H](CC2=CC=CC(C)=C2)NC(C3=C(F)C=C(F)C=C3)=O)=O)C#N)=CC=C1)=O;0.109;0.406;0.661;25.94;;;;
1b;OC(C1=CC(COC[C@H](NC([C@H](CC2=CC=CC(C)=C2)NC(C3=CC=C(F)C=C3)=O)=O)C#N)=CC=C1)=O;0.042;0.046;0.220;8.807;;;;
1c;OC(C1=CC(COC[C@H](NC([C@H](CC2=CC=CC(C)=C2)NC(C(C3=CC=CC=C3)C4=CC=CC=C4)=O)=O)C#N)=CC=C1)=O;0.004;0.024;0.024;2.503;;;;
1d;OC(C1=CC(COC[C@H](NC([C@H](CC2=CC=CC(I)=C2)NC(C3=CC=C(F)C=C3)=O)=O)C#N)=CC=C1)=O;0.043;0.037;0.696;34.92;;;;
1e;OC(C1=CC(COC[C@H](NC([C@H](CC2=CC=CC(I)=C2)NC(C(C3=CC=CC=C3)C4=CC=CC=C4)=O)=O)C#N)=CC=C1)=O;0.003;0.012;0.059;5.646;;;;
35a;O=C([C@H](CC1=CC=CC(C)=C1)NC(C2=CC=C(F)C=C2)=O)N[C@@H](CCCN3C=C(C(O)=O)N=N3)C#N;4.118;0.270;0.694;30.41;;;;
35b;O=C([C@H](CC1=CC=CC(C)=C1)NC(C2=CC=C(F)C=C2)=O)N[C@@H](CCCN3C=C(CC(O)=O)N=N3)C#N;4.580;0.319;0.537;25.21;;;;
35c;O=C([C@H](CC1=CC=CC(C)=C1)NC(C2=CC=C(F)C=C2)=O)N[C@@H](CCCCN3C=C(C(O)=O)N=N3)C#N;2.343;0.215;0.474;25.99;;;;
42;O=C([C@H](CC1=CC=CC(C)=C1)NC(C2=CC=C(F)C=C2)=O)N[C@@H](COCC3=CN(CC(OC)=O)N=N3)C#N;0.859;0.110;0.049;4.043;;;;
43;O=C([C@H](CC1=CC=CC(C)=C1)NC(C2=CC=C(F)C=C2)=O)N[C@@H](COCC3=CN(CC(O)=O)N=N3)C#N;1.612;0.191;0.523;19.11;;;;
56a;O=C([C@H](CC1=CC=CC(C)=C1)NC(C2=CC=C(F)C=C2)=O)NCC#N;1.187;0.055;0.049;2.121;;;;
56b;OC(C1=CC(COC[C@H](NC([C@H](CC2=CC=CC(C)=C2)NC(C(C3=CC=CC=C3)C4=CC=CC=C4)=O)=O)C#N)=CC=C1)=O;0.086;0.038;0.007;11.02;;;;
2a;OC(C1=CC(COC[C@H](NC([C@H](CC2=CC=CC(C)=C2)NC(C3=C(F)C=C(F)C=C3)=O)=O)C#C)=CC=C1)=O;;;;;22;58;30;3
2b;OC(C1=CC(COC[C@H](NC([C@H](CC2=CC=CC(C)=C2)NC(C3=CC=C(F)C=C3)=O)=O)C#C)=CC=C1)=O;;;;;85;682;281;48
2c;OC(C1=CC(COC[C@H](NC([C@H](CC2=CC=CC(C)=C2)NC(C(C3=CC=CC=C3)C4=CC=CC=C4)=O)=O)C#C)=CC=C1)=O;;;;;771;47;381;n.i.
2d;OC(C1=CC(COC[C@H](NC([C@H](CC2=CC=CC(C)=C2)NC(C3=CC=C(C4=CC=CC=C4)C=C3)=O)=O)C#C)=CC=C1)=O;;;;;41;n.i.;n.i.;n.i.
2e;OC(C1=CC(COC[C@H](NC([C@H](CC2=CC=CC(C)=C2)NC(C3=CC=C(I)C=C3)=O)=O)C#C)=CC=C1)=O;;;;;152;113;82;476
2f;OC(C1=CC(COC[C@H](NC([C@H](CC2=CC=CC(C)=C2)NC(C3=CC(I)=CC=C3)=O)=O)C#C)=CC=C1)=O;;;;;45;n.i.;1968;n.i.
2g;OC(C1=CC(COC[C@H](NC([C@H](CC2=CC=CC(C)=C2)NC(C3=CC=CC=C3)=O)=O)C#C)=CC=C1)=O;;;;;88;654;222;32
2h;OC(C1=CC(COC[C@H](NC([C@H](CC2=CC=CC(C)=C2)NC(C3=CC(F)=CC=C3)=O)=O)C#C)=CC=C1)=O;;;;;109;1579;483;27
2i;OC(C1=CC(COC[C@H](NC([C@H](CC2=CC=CC(C)=C2)NC(C3=CC(Br)=CC=C3)=O)=O)C#C)=CC=C1)=O;;;;;87;570;1309;n.i.
2j;OC(C1=CC(COC[C@H](NC([C@H](CC2=CC=CC(C)=C2)NC(C3=CC(C(F)(F)F)=CC=C3)=O)=O)C#C)=CC=C1)=O;;;;;29;141;327;n.i.
2k;OC(C1=CC(COC[C@H](NC([C@H](CC2=CC=CC(I)=C2)NC(C3=CC=C(F)C=C3)=O)=O)C#C)=CC=C1)=O;;;;;1179;10133;2128;121
2l;OC(C1=CC(COC[C@H](NC([C@H](CC2=CC=CC(I)=C2)NC(C(C3=CC=CC=C3)C4=CC=CC=C4)=O)=O)C#C)=CC=C1)=O;;;;;301;859;552;76
2m;OC(C1=CC(COC[C@H](NC([C@H](CC2=CC=CC(I)=C2)NC(C3=CC(I)=CC=C3)=O)=O)C#C)=CC=C1)=O;;;;;225;4368;2876;n.i.
28;O=C([C@H](CC1=CC=CC(C)=C1)NC(C2=CC=C(F)C=C2)=O)N[C@@H](CCCN3C=C(C(O)=O)N=N3)C#C;;;;;n.d.;594;214;40
53k;O=C(OCC=C)C1=CC(COC[C@H](NC([C@H](CC2=CC=CC(I)=C2)NC(C3=CC=C(F)C=C3)=O)=O)C#C)=CC=C1;;;;;141;3589;1246;n.i.
56c;O=C([C@H](CC1=CC=CC(C)=C1)NC(C2=CC=C(F)C=C2)=O)NCC#C;;;;;n.i.;n.i.;19;n.i.
56d;O=C([C@H](CC1=CC=CC(C)=C1)NC(C(C2=CC=CC=C2)C3=CC=CC=C3)=O)NCC#C;;;;;n.i.;n.i.;n.i.;n.i.
56e;O=C([C@H](CC(C)C)NC(C1=CC=C(F)C=C1)=O)NCC#C;;;;;4;79;93;260
56f;O=C([C@H](CC1CCCCC1)NC(C2=CC=C(F)C=C2)=O)NCC#C;;;;;34;283;n.i.;179
62;O=C([C@H](CS(CC(C)C)(=O)=O)NC(C1=CC=C(F)C=C1)=O)NCC#C;;;;;n.i.;14;n.i.;n.i.
63;O=C(OC)C1=CC(COC[C@H](NC([C@H](CC2=CC=CC(C)=C2)NC(C3=CC=C(F)C=C3)=O)=O)C#C)=CC=C1;;;;;n.i.;12;79;n.i.
64;O=C(OC)C1=CC(COC[C@H](NC([C@H](CC2=CC=CC(C)=C2)NC(C3=CC(I)=CC=C3)=O)=O)C#C)=CC=C1;;;;;15;137;537;n.i.