ONTOLOGY ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count BP GO:0002366 leukocyte activation involved in immune response 10/117 285/18800 1.17189680317659e-05 0.00975516667347732 0.0086027916439351 BATF/LGALS1/MAD2L2/FES/PYCARD/VAMP8/RAC2/APBB1IP/ITGB2/PRAM1 10 BP GO:0043300 regulation of leukocyte degranulation 5/117 49/18800 1.31270211075825e-05 0.00975516667347732 0.0086027916439351 FES/VAMP8/RAC2/ITGB2/PRAM1 5 BP GO:0002263 cell activation involved in immune response 10/117 289/18800 1.32243560869552e-05 0.00975516667347732 0.0086027916439351 BATF/LGALS1/MAD2L2/FES/PYCARD/VAMP8/RAC2/APBB1IP/ITGB2/PRAM1 10 BP GO:0002275 myeloid cell activation involved in immune response 6/117 93/18800 2.50493494216591e-05 0.0114977389644428 0.0101395143720489 FES/PYCARD/VAMP8/RAC2/ITGB2/PRAM1 6 BP GO:1903305 regulation of regulated secretory pathway 7/117 140/18800 2.73969008836984e-05 0.0114977389644428 0.0101395143720489 MICAL1/DTNBP1/FES/VAMP8/RAC2/ITGB2/PRAM1 7 BP GO:0002886 regulation of myeloid leukocyte mediated immunity 5/117 59/18800 3.279838347681e-05 0.0114977389644428 0.0101395143720489 FES/VAMP8/RAC2/ITGB2/PRAM1 5 BP GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage 6/117 101/18800 4.00005190645499e-05 0.0114977389644428 0.0101395143720489 MUC1/HTRA2/BAD/PYCARD/SHISA5/BCL2L1 6 BP GO:0017157 regulation of exocytosis 8/117 204/18800 4.1564352334181e-05 0.0114977389644428 0.0101395143720489 MICAL1/DTNBP1/FES/VAMP8/CHMP2A/RAC2/ITGB2/PRAM1 8 BP GO:0051258 protein polymerization 9/117 277/18800 5.92554675433631e-05 0.0145702610748292 0.0128490803304556 ARPC1B/PSTPIP1/ARPC4/FES/PYCARD/MSRB2/TMSB10/PINK1/CHMP2A 9 BP GO:0070997 neuron death 10/117 353/18800 7.21855079062516e-05 0.0159746528996535 0.0140875717534937 GAPDH/DTNBP1/GBA/HTRA2/BAD/PINK1/CDC34/ITGB2/UBB/BCL2L1 10 BP GO:1904923 regulation of autophagy of mitochondrion in response to mitochondrial depolarization 3/117 14/18800 8.13370189680836e-05 0.0161906548483412 0.014278057454194 GBA/HTRA2/PINK1 3 BP GO:0097193 intrinsic apoptotic signaling pathway 9/117 295/18800 9.59210583274479e-05 0.0161906548483412 0.014278057454194 CASP4/MUC1/HTRA2/BAD/PYCARD/SHISA5/PINK1/UBB/BCL2L1 9 BP GO:2001242 regulation of intrinsic apoptotic signaling pathway 7/117 171/18800 9.75496085846767e-05 0.0161906548483412 0.014278057454194 MUC1/HTRA2/BAD/PYCARD/PINK1/UBB/BCL2L1 7 BP GO:0002274 myeloid leukocyte activation 8/117 232/18800 0.00010242619425069 0.0161906548483412 0.014278057454194 BATF/CST7/FES/PYCARD/VAMP8/RAC2/ITGB2/PRAM1 8 BP GO:0043299 leukocyte degranulation 5/117 76/18800 0.000111272660948353 0.0164164265785804 0.0144771588349647 FES/VAMP8/RAC2/ITGB2/PRAM1 5 BP GO:1903533 regulation of protein targeting 5/117 78/18800 0.000125900196880753 0.0174135709810692 0.0153565108563761 STOM/HTRA2/PINK1/RAC2/ITGB2 5 BP GO:0006839 mitochondrial transport 7/117 182/18800 0.00014378173248328 0.0184432114590475 0.0162645202012387 HTRA2/TIMM17B/BAD/SLC25A20/PINK1/RAC2/BCL2L1 7 BP GO:1901214 regulation of neuron death 9/117 313/18800 0.000150012564962881 0.0184432114590475 0.0162645202012387 DTNBP1/GBA/HTRA2/BAD/PINK1/CDC34/ITGB2/UBB/BCL2L1 9 BP GO:0090199 regulation of release of cytochrome c from mitochondria 4/117 46/18800 0.000190013571023367 0.0221315806670901 0.0195171834170262 BAD/PYCARD/PINK1/BCL2L1 4 BP GO:0098780 response to mitochondrial depolarisation 3/117 19/18800 0.000211663054480971 0.0234205169783194 0.0206538580530379 GBA/HTRA2/PINK1 3 BP GO:0032388 positive regulation of intracellular transport 7/117 198/18800 0.000241327043804318 0.0244582999924647 0.0215690480586151 STOM/EDEM2/HTRA2/PINK1/RAC2/EHD1/ITGB2 7 BP GO:0008154 actin polymerization or depolymerization 7/117 199/18800 0.000248855031790415 0.0244582999924647 0.0215690480586151 ARPC1B/MICAL1/PSTPIP1/ARPC4/PYCARD/MSRB2/TMSB10 7 BP GO:0010506 regulation of autophagy 9/117 336/18800 0.000254198327983139 0.0244582999924647 0.0215690480586151 GAPDH/ATP6V0E1/GPR137/GBA/ATP6V1D/HTRA2/BAD/PYCARD/PINK1 9 BP GO:1901739 regulation of myoblast fusion 3/117 21/18800 0.000287892533799246 0.0265460907207388 0.023410208669465 CFLAR/CD53/EHD1 3 BP GO:0006887 exocytosis 9/117 357/18800 0.000396129546752054 0.034701046674886 0.0306018220254661 MICAL1/DTNBP1/EXOC6/FES/VAMP8/CHMP2A/RAC2/ITGB2/PRAM1 9 BP GO:0001836 release of cytochrome c from mitochondria 4/117 56/18800 0.000407694176930428 0.034701046674886 0.0306018220254661 BAD/PYCARD/PINK1/BCL2L1 4 BP GO:0090316 positive regulation of intracellular protein transport 6/117 156/18800 0.000434609074327513 0.0356218474624736 0.0314138488812168 STOM/EDEM2/HTRA2/PINK1/RAC2/ITGB2 6 BP GO:0002444 myeloid leukocyte mediated immunity 5/117 104/18800 0.000482411918212351 0.037536867102508 0.0331026478027207 FES/VAMP8/RAC2/ITGB2/PRAM1 5 BP GO:0033157 regulation of intracellular protein transport 7/117 224/18800 0.000507794151446038 0.037536867102508 0.0331026478027207 STOM/EDEM2/DERL2/HTRA2/PINK1/RAC2/ITGB2 7 BP GO:0007015 actin filament organization 10/117 450/18800 0.000508859472695544 0.037536867102508 0.0331026478027207 ARPC1B/MICAL1/MAD2L2/GMFG/PSTPIP1/ARPC4/PYCARD/MSRB2/TMSB10/RAC2 10 BP GO:0007229 integrin-mediated signaling pathway 5/117 107/18800 0.000549487979686867 0.03804841563146 0.0335537672512792 ILK/VAV1/FERMT3/ITGB2/PRAM1 5 BP GO:0090200 positive regulation of release of cytochrome c from mitochondria 3/117 26/18800 0.000550180433893683 0.03804841563146 0.0335537672512792 BAD/PYCARD/PINK1 3 BP GO:0007159 leukocyte cell-cell adhesion 9/117 381/18800 0.000632669399828239 0.0407656585543733 0.0359500230503047 LGALS1/FLOT2/VAV1/BAD/PYCARD/FERMT3/TNIP1/RAC2/ITGB2 9 BP GO:0045055 regulated exocytosis 7/117 234/18800 0.000657899505830614 0.0407656585543733 0.0359500230503047 MICAL1/DTNBP1/FES/VAMP8/RAC2/ITGB2/PRAM1 7 BP GO:0016236 macroautophagy 8/117 306/18800 0.000661029716326075 0.0407656585543733 0.0359500230503047 GAPDH/ATP6V0E1/GBA/ATP6V1D/HTRA2/VAMP8/PINK1/CHMP2A 8 BP GO:0030041 actin filament polymerization 6/117 169/18800 0.000663155765005621 0.0407656585543733 0.0359500230503047 ARPC1B/PSTPIP1/ARPC4/PYCARD/MSRB2/TMSB10 6 BP GO:0002703 regulation of leukocyte mediated immunity 7/117 236/18800 0.00069175976773401 0.0413747125944693 0.0364871297120584 MAD2L2/FES/VAV1/VAMP8/RAC2/ITGB2/PRAM1 7 BP GO:0050727 regulation of inflammatory response 9/117 394/18800 0.00080274887268992 0.0467495593490208 0.04122704736751 CASP4/CST7/LGALS1/RHBDF2/GBA/PYCARD/GPSM3/VAMP8/TNIP1 9 BP GO:0060142 regulation of syncytium formation by plasma membrane fusion 3/117 30/18800 0.000843703602175048 0.0478747710670098 0.0422193381493263 CFLAR/CD53/EHD1 3 BP GO:0051881 regulation of mitochondrial membrane potential 4/117 71/18800 0.00100398494759821 0.0538204024452599 0.0474626138052711 BAD/PINK1/UBB/BCL2L1 4 BP GO:0043304 regulation of mast cell degranulation 3/117 32/18800 0.00102144460131085 0.0538204024452599 0.0474626138052711 FES/VAMP8/RAC2 3 BP GO:1903955 positive regulation of protein targeting to mitochondrion 3/117 32/18800 0.00102144460131085 0.0538204024452599 0.0474626138052711 HTRA2/PINK1/RAC2 3 BP GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling 7/117 254/18800 0.00106290542707431 0.0547025513980336 0.0482405547563223 GAPDH/LGALS1/CFLAR/PYCARD/SHISA5/TNIP1/PINK1 7 BP GO:0032386 regulation of intracellular transport 8/117 332/18800 0.0011190879251145 0.0562850358699634 0.0496361007933561 STOM/EDEM2/DERL2/HTRA2/PINK1/RAC2/EHD1/ITGB2 8 BP GO:0016032 viral process 9/117 418/18800 0.00121420918356981 0.0580182754217174 0.0511645932560535 STOM/EDEM2/LGALS1/MCTS1/VAMP8/PARP10/TNIP1/CHMP2A/BCL2L1 9 BP GO:0033006 regulation of mast cell activation involved in immune response 3/117 34/18800 0.00122122633245269 0.0580182754217174 0.0511645932560535 FES/VAMP8/RAC2 3 BP GO:0010822 positive regulation of mitochondrion organization 4/117 75/18800 0.00123220015581596 0.0580182754217174 0.0511645932560535 HTRA2/BAD/PYCARD/PINK1 4 BP GO:1903749 positive regulation of establishment of protein localization to mitochondrion 3/117 36/18800 0.00144403058087443 0.0636008605619685 0.0560877092215329 HTRA2/PINK1/RAC2 3 BP GO:0030705 cytoskeleton-dependent intracellular transport 6/117 197/18800 0.00146467955282881 0.0636008605619685 0.0560877092215329 BLOC1S1/FLOT2/HOOK2/DTNBP1/TUBA1A/UBB 6 BP GO:0032418 lysosome localization 4/117 79/18800 0.0014944621550937 0.0636008605619685 0.0560877092215329 BLOC1S1/FES/VAMP8/RAC2 4 BP GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator 4/117 79/18800 0.0014944621550937 0.0636008605619685 0.0560877092215329 MUC1/PYCARD/SHISA5/UBB 4 BP GO:1990849 vacuolar localization 4/117 79/18800 0.0014944621550937 0.0636008605619685 0.0560877092215329 BLOC1S1/FES/VAMP8/RAC2 4 BP GO:0032271 regulation of protein polymerization 6/117 201/18800 0.00162217603448861 0.0660970016796791 0.0582889819079245 ARPC1B/ARPC4/FES/PYCARD/TMSB10/PINK1 6 BP GO:0002697 regulation of immune effector process 8/117 353/18800 0.00165002007269052 0.0660970016796791 0.0582889819079245 MAD2L2/FES/VAV1/VAMP8/CUEDC2/RAC2/ITGB2/PRAM1 8 BP GO:0010944 negative regulation of transcription by competitive promoter binding 2/117 10/18800 0.00167258567287032 0.0660970016796791 0.0582889819079245 MAD2L2/MUC1 2 BP GO:0060155 platelet dense granule organization 2/117 10/18800 0.00167258567287032 0.0660970016796791 0.0582889819079245 BLOC1S1/DTNBP1 2 BP GO:2001021 negative regulation of response to DNA damage stimulus 4/117 82/18800 0.00171503597006501 0.0665855193290154 0.0587197911080432 MAD2L2/MUC1/THOC5/BCL2L1 4 BP GO:0048489 synaptic vesicle transport 3/117 40/18800 0.00196240599380351 0.0748759390394341 0.0660308659258024 BLOC1S1/DTNBP1/PINK1 3 BP GO:0009150 purine ribonucleotide metabolic process 8/117 366/18800 0.00206779054111611 0.0752738979713047 0.0663818140836678 GAPDH/TPST2/GALK1/BAD/PGAM1/PINK1/IMPDH1/ACSS2 8 BP GO:0044403 biological process involved in symbiotic interaction 7/117 286/18800 0.00209330579143138 0.0752738979713047 0.0663818140836678 GAPDH/STOM/LGALS1/THOC5/VAMP8/CHMP2A/BCL2L1 7 BP GO:0033574 response to testosterone 3/117 41/18800 0.00210779767601591 0.0752738979713047 0.0663818140836678 CFLAR/GBA/BAD 3 BP GO:0050729 positive regulation of inflammatory response 5/117 145/18800 0.00213646773773905 0.0752738979713047 0.0663818140836678 LGALS1/PYCARD/GPSM3/VAMP8/TNIP1 5 BP GO:0045862 positive regulation of proteolysis 8/117 369/18800 0.00217511258700475 0.0752738979713047 0.0663818140836678 CFLAR/AURKAIP1/GBA/HTRA2/BAD/PYCARD/TNIP1/PINK1 8 BP GO:0007249 I-kappaB kinase/NF-kappaB signaling 7/117 288/18800 0.00217692248990669 0.0752738979713047 0.0663818140836678 GAPDH/LGALS1/CFLAR/PYCARD/SHISA5/TNIP1/PINK1 7 BP GO:2001233 regulation of apoptotic signaling pathway 8/117 370/18800 0.00221184557759682 0.0753048348187964 0.0664090963702754 CFLAR/MUC1/HTRA2/BAD/PYCARD/PINK1/UBB/BCL2L1 8 BP GO:0034314 Arp2/3 complex-mediated actin nucleation 3/117 42/18800 0.00225971647397935 0.0757689781350954 0.0668184105702984 ARPC1B/GMFG/ARPC4 3 BP GO:0010821 regulation of mitochondrion organization 5/117 148/18800 0.00233560422816939 0.0758415939123001 0.0668824482666561 HTRA2/BAD/PYCARD/PINK1/BCL2L1 5 BP GO:0051222 positive regulation of protein transport 7/117 293/18800 0.00239729031335325 0.0758415939123001 0.0668824482666561 STOM/EDEM2/HTRA2/BAD/PINK1/RAC2/ITGB2 7 BP GO:0046031 ADP metabolic process 4/117 90/18800 0.00241196186299902 0.0758415939123001 0.0668824482666561 GAPDH/GALK1/BAD/PGAM1 4 BP GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 3/117 43/18800 0.00241826177586078 0.0758415939123001 0.0668824482666561 MUC1/PYCARD/SHISA5 3 BP GO:0043312 neutrophil degranulation 2/117 12/18800 0.0024332368584606 0.0758415939123001 0.0668824482666561 ITGB2/PRAM1 2 BP GO:1903214 regulation of protein targeting to mitochondrion 3/117 44/18800 0.00258353039454617 0.0794076772657037 0.0700272712205934 HTRA2/PINK1/RAC2 3 BP GO:0007520 myoblast fusion 3/117 45/18800 0.00275561660180358 0.0820077860446981 0.0723202298983853 CFLAR/CD53/EHD1 3 BP GO:0033003 regulation of mast cell activation 3/117 45/18800 0.00275561660180358 0.0820077860446981 0.0723202298983853 FES/VAMP8/RAC2 3 BP GO:0009259 ribonucleotide metabolic process 8/117 384/18800 0.00277929686098164 0.0820077860446981 0.0723202298983853 GAPDH/TPST2/GALK1/BAD/PGAM1/PINK1/IMPDH1/ACSS2 8 BP GO:1904925 positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization 2/117 13/18800 0.00286397103227979 0.0833943144004627 0.0735429680588189 GBA/PINK1 2 BP GO:0016241 regulation of macroautophagy 5/117 158/18800 0.00309744110671931 0.0876701913453767 0.0773137368917299 GAPDH/ATP6V0E1/GBA/ATP6V1D/PINK1 5 BP GO:2000116 regulation of cysteine-type endopeptidase activity 6/117 229/18800 0.00311310787918795 0.0876701913453767 0.0773137368917299 CST7/MICAL1/CFLAR/HTRA2/BAD/PYCARD 6 BP GO:0002532 production of molecular mediator involved in inflammatory response 4/117 97/18800 0.00316369071723873 0.0876701913453767 0.0773137368917299 PYCARD/GPSM3/VAMP8/CUEDC2 4 BP GO:1904951 positive regulation of establishment of protein localization 7/117 309/18800 0.00321978111445335 0.0876701913453767 0.0773137368917299 STOM/EDEM2/HTRA2/BAD/PINK1/RAC2/ITGB2 7 BP GO:0006163 purine nucleotide metabolic process 8/117 394/18800 0.00325004210541687 0.0876701913453767 0.0773137368917299 GAPDH/TPST2/GALK1/BAD/PGAM1/PINK1/IMPDH1/ACSS2 8 BP GO:0019693 ribose phosphate metabolic process 8/117 394/18800 0.00325004210541687 0.0876701913453767 0.0773137368917299 GAPDH/TPST2/GALK1/BAD/PGAM1/PINK1/IMPDH1/ACSS2 8 BP GO:0090239 regulation of histone H4 acetylation 2/117 14/18800 0.00332774336783174 0.0876701913453767 0.0773137368917299 MUC1/TAF7 2 BP GO:1904152 regulation of retrograde protein transport, ER to cytosol 2/117 14/18800 0.00332774336783174 0.0876701913453767 0.0773137368917299 EDEM2/DERL2 2 BP GO:0009117 nucleotide metabolic process 9/117 487/18800 0.00340897883119175 0.0887537665109099 0.0782693096350403 GAPDH/TPST2/GALK1/BAD/PGAM1/PARP10/PINK1/IMPDH1/ACSS2 9 BP GO:0006626 protein targeting to mitochondrion 4/117 101/18800 0.00365797901618822 0.0909979197269976 0.0802483616780524 HTRA2/TIMM17B/PINK1/RAC2 4 BP GO:0043303 mast cell degranulation 3/117 50/18800 0.00372143733052484 0.0909979197269976 0.0802483616780524 FES/VAMP8/RAC2 3 BP GO:1903747 regulation of establishment of protein localization to mitochondrion 3/117 50/18800 0.00372143733052484 0.0909979197269976 0.0802483616780524 HTRA2/PINK1/RAC2 3 BP GO:0051656 establishment of organelle localization 8/117 404/18800 0.00378072095880301 0.0909979197269976 0.0802483616780524 BLOC1S1/DTNBP1/FES/VAMP8/PINK1/CHMP2A/RAC2/UBB 8 BP GO:2001243 negative regulation of intrinsic apoptotic signaling pathway 4/117 102/18800 0.00378927393650827 0.0909979197269976 0.0802483616780524 MUC1/HTRA2/PINK1/BCL2L1 4 BP GO:0006753 nucleoside phosphate metabolic process 9/117 495/18800 0.00379297182127007 0.0909979197269976 0.0802483616780524 GAPDH/TPST2/GALK1/BAD/PGAM1/PARP10/PINK1/IMPDH1/ACSS2 9 BP GO:0051223 regulation of protein transport 9/117 495/18800 0.00379297182127007 0.0909979197269976 0.0802483616780524 STOM/EDEM2/DERL2/RHBDF2/HTRA2/BAD/PINK1/RAC2/ITGB2 9 BP GO:1902563 regulation of neutrophil activation 2/117 15/18800 0.00382413309291043 0.0909979197269976 0.0802483616780524 ITGB2/PRAM1 2 BP GO:0009135 purine nucleoside diphosphate metabolic process 4/117 103/18800 0.00392372997491302 0.0914022572050791 0.0806049348863019 GAPDH/GALK1/BAD/PGAM1 4 BP GO:0009179 purine ribonucleoside diphosphate metabolic process 4/117 103/18800 0.00392372997491302 0.0914022572050791 0.0806049348863019 GAPDH/GALK1/BAD/PGAM1 4 BP GO:0002279 mast cell activation involved in immune response 3/117 52/18800 0.00415851318353882 0.0939060170935857 0.0828129263402896 FES/VAMP8/RAC2 3 BP GO:0002448 mast cell mediated immunity 3/117 52/18800 0.00415851318353882 0.0939060170935857 0.0828129263402896 FES/VAMP8/RAC2 3 BP GO:0097479 synaptic vesicle localization 3/117 52/18800 0.00415851318353882 0.0939060170935857 0.0828129263402896 BLOC1S1/DTNBP1/PINK1 3 BP GO:0072331 signal transduction by p53 class mediator 5/117 170/18800 0.00423110302098654 0.0945801109640729 0.0834073896960026 BATF/MUC1/PYCARD/SHISA5/UBB 5 BP GO:1903039 positive regulation of leukocyte cell-cell adhesion 6/117 245/18800 0.00432919764601996 0.0949190266600735 0.0837062693784461 LGALS1/FLOT2/VAV1/BAD/PYCARD/ITGB2 6 BP GO:1901741 positive regulation of myoblast fusion 2/117 16/18800 0.00435272331500361 0.0949190266600735 0.0837062693784461 CD53/EHD1 2 BP GO:0006898 receptor-mediated endocytosis 6/117 246/18800 0.00441536809128335 0.0949190266600735 0.0837062693784461 AP1S1/DTNBP1/CLTB/AP2S1/ASGR1/ITGB2 6 BP GO:1905475 regulation of protein localization to membrane 5/117 172/18800 0.00444539058841096 0.0949190266600735 0.0837062693784461 STOM/VAMP8/STX8/ITGB2/BCL2L1 5 BP GO:0008637 apoptotic mitochondrial changes 4/117 107/18800 0.00449387283876663 0.0949190266600735 0.0837062693784461 BAD/PYCARD/PINK1/BCL2L1 4 BP GO:0072521 purine-containing compound metabolic process 8/117 416/18800 0.00450361400782093 0.0949190266600735 0.0837062693784461 GAPDH/TPST2/GALK1/BAD/PGAM1/PINK1/IMPDH1/ACSS2 8 BP GO:0002699 positive regulation of immune effector process 6/117 248/18800 0.00459150463750549 0.0958584883282986 0.0845347527103791 MAD2L2/FES/VAV1/VAMP8/RAC2/ITGB2 6 BP GO:0002696 positive regulation of leukocyte activation 8/117 421/18800 0.00483447260708989 0.0997988325589629 0.0880096252119377 LGALS1/MAD2L2/FLOT2/VAV1/BAD/PYCARD/VAMP8/ITGB2 8 BP GO:0045010 actin nucleation 3/117 55/18800 0.00487043556998102 0.0997988325589629 0.0880096252119377 ARPC1B/GMFG/ARPC4 3 BP GO:1990778 protein localization to cell periphery 7/117 337/18800 0.00515898291755592 0.104741552261938 0.0923684628599583 FLOT2/DTNBP1/VAMP8/STX8/EHD1/PRAM1/BCL2L1 7 BP GO:0009185 ribonucleoside diphosphate metabolic process 4/117 112/18800 0.00528186814681159 0.106261583717219 0.0937089334372123 GAPDH/GALK1/BAD/PGAM1 4 BP GO:0042772 DNA damage response, signal transduction resulting in transcription 2/117 18/18800 0.00550485689098463 0.107807507077425 0.0950722373161202 MAD2L2/MUC1 2 BP GO:0048268 clathrin coat assembly 2/117 18/18800 0.00550485689098463 0.107807507077425 0.0950722373161202 CLTB/AP2S1 2 BP GO:0097284 hepatocyte apoptotic process 2/117 18/18800 0.00550485689098463 0.107807507077425 0.0950722373161202 CFLAR/BCL2L1 2 BP GO:1903131 mononuclear cell differentiation 8/117 433/18800 0.00570480590611731 0.110743293598576 0.0976612202210665 BATF/LGALS1/GBA/FES/VAV1/BAD/THOC5/LYL1 8 BP GO:0000768 syncytium formation by plasma membrane fusion 3/117 59/18800 0.00592769785025881 0.110784448031744 0.0976975130928976 CFLAR/CD53/EHD1 3 BP GO:0140253 cell-cell fusion 3/117 59/18800 0.00592769785025881 0.110784448031744 0.0976975130928976 CFLAR/CD53/EHD1 3 BP GO:0050867 positive regulation of cell activation 8/117 436/18800 0.00594000226368173 0.110784448031744 0.0976975130928976 LGALS1/MAD2L2/FLOT2/VAV1/BAD/PYCARD/VAMP8/ITGB2 8 BP GO:0002283 neutrophil activation involved in immune response 2/117 19/18800 0.00612758557763211 0.110784448031744 0.0976975130928976 ITGB2/PRAM1 2 BP GO:0048490 anterograde synaptic vesicle transport 2/117 19/18800 0.00612758557763211 0.110784448031744 0.0976975130928976 BLOC1S1/DTNBP1 2 BP GO:0097202 activation of cysteine-type endopeptidase activity 2/117 19/18800 0.00612758557763211 0.110784448031744 0.0976975130928976 BAD/PYCARD 2 BP GO:0099514 synaptic vesicle cytoskeletal transport 2/117 19/18800 0.00612758557763211 0.110784448031744 0.0976975130928976 BLOC1S1/DTNBP1 2 BP GO:0099517 synaptic vesicle transport along microtubule 2/117 19/18800 0.00612758557763211 0.110784448031744 0.0976975130928976 BLOC1S1/DTNBP1 2 BP GO:0007006 mitochondrial membrane organization 4/117 117/18800 0.00615747271030479 0.110784448031744 0.0976975130928976 MTX1/BAD/PINK1/BCL2L1 4 BP GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling 5/117 188/18800 0.00644663861143393 0.115051703605672 0.101460678994894 GAPDH/LGALS1/CFLAR/SHISA5/PINK1 5 BP GO:0032956 regulation of actin cytoskeleton organization 7/117 352/18800 0.00650508144477205 0.115165961898244 0.101561439988273 ARPC1B/GMFG/ARPC4/FES/PYCARD/TMSB10/RAC2 7 BP GO:0072655 establishment of protein localization to mitochondrion 4/117 120/18800 0.00672657314083078 0.115204970008975 0.101595840082117 HTRA2/TIMM17B/PINK1/RAC2 4 BP GO:1901654 response to ketone 5/117 190/18800 0.00673481440815121 0.115204970008975 0.101595840082117 CFLAR/GBA/BAD/IGFBP7/BCL2L1 5 BP GO:0045785 positive regulation of cell adhesion 8/117 446/18800 0.00677775071916832 0.115204970008975 0.101595840082117 LGALS1/FLOT2/ILK/VAV1/BAD/PYCARD/APBB1IP/ITGB2 8 BP GO:0010310 regulation of hydrogen peroxide metabolic process 2/117 20/18800 0.00678088536534393 0.115204970008975 0.101595840082117 PINK1/RAC2 2 BP GO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 2/117 20/18800 0.00678088536534393 0.115204970008975 0.101595840082117 HTRA2/PINK1 2 BP GO:0051701 biological process involved in interaction with host 5/117 191/18800 0.00688223836911838 0.115204970008975 0.101595840082117 LGALS1/THOC5/VAMP8/CHMP2A/BCL2L1 5 BP GO:0007041 lysosomal transport 4/117 121/18800 0.00692375102177751 0.115204970008975 0.101595840082117 HOOK2/PINK1/STX8/CHMP2A 4 BP GO:1903008 organelle disassembly 4/117 121/18800 0.00692375102177751 0.115204970008975 0.101595840082117 GBA/HTRA2/MCTS1/PINK1 4 BP GO:0010952 positive regulation of peptidase activity 5/117 192/18800 0.00703190951959898 0.11613146094681 0.102412884912306 CFLAR/HTRA2/BAD/PYCARD/PINK1 5 BP GO:0006949 syncytium formation 3/117 63/18800 0.00711210171914839 0.116585785959077 0.102813540641724 CFLAR/CD53/EHD1 3 BP GO:0046034 ATP metabolic process 6/117 273/18800 0.0072548712669725 0.11805169201331 0.104106279635968 GAPDH/GALK1/COX6A1/BAD/PGAM1/PINK1 6 BP GO:1903532 positive regulation of secretion by cell 6/117 274/18800 0.00738052046414203 0.11921964808136 0.105136265390083 DTNBP1/BAD/VAMP8/PINK1/CHMP2A/ITGB2 6 BP GO:0022407 regulation of cell-cell adhesion 8/117 456/18800 0.00770232426467962 0.120705451460713 0.106446551244161 LGALS1/MAD2L2/FLOT2/VAV1/BAD/PYCARD/FERMT3/ITGB2 8 BP GO:0052547 regulation of peptidase activity 8/117 456/18800 0.00770232426467962 0.120705451460713 0.106446551244161 GAPDH/CST7/MICAL1/CFLAR/HTRA2/BAD/PYCARD/PINK1 8 BP GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 4/117 125/18800 0.00775066020873953 0.120705451460713 0.106446551244161 CFLAR/HTRA2/BAD/PYCARD 4 BP GO:0070585 protein localization to mitochondrion 4/117 125/18800 0.00775066020873953 0.120705451460713 0.106446551244161 HTRA2/TIMM17B/PINK1/RAC2 4 BP GO:0045576 mast cell activation 3/117 65/18800 0.00775310185680592 0.120705451460713 0.106446551244161 FES/VAMP8/RAC2 3 BP GO:0002443 leukocyte mediated immunity 8/117 457/18800 0.00779976482552279 0.120705451460713 0.106446551244161 BATF/MAD2L2/FES/VAV1/VAMP8/RAC2/ITGB2/PRAM1 8 BP GO:0038034 signal transduction in absence of ligand 3/117 66/18800 0.00808597855751989 0.123408762398562 0.108830520839505 HTRA2/BAD/BCL2L1 3 BP GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand 3/117 66/18800 0.00808597855751989 0.123408762398562 0.108830520839505 HTRA2/BAD/BCL2L1 3 BP GO:0072659 protein localization to plasma membrane 6/117 283/18800 0.00858324941380195 0.130100896936601 0.114732115451974 FLOT2/VAMP8/STX8/EHD1/PRAM1/BCL2L1 6 BP GO:0009132 nucleoside diphosphate metabolic process 4/117 130/18800 0.00887243795277324 0.133569423057736 0.117790905581393 GAPDH/GALK1/BAD/PGAM1 4 BP GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 5/117 204/18800 0.00900946143381735 0.134715798331336 0.118801859874092 MICAL1/CFLAR/HTRA2/BAD/PYCARD 5 BP GO:1902903 regulation of supramolecular fiber organization 7/117 376/18800 0.00918181105645651 0.136371462200928 0.120261940647618 ARPC1B/GMFG/ARPC4/FES/PYCARD/TMSB10/PFDN5 7 BP GO:0031349 positive regulation of defense response 6/117 289/18800 0.00945953157279849 0.139273740889088 0.122821373990234 LGALS1/VAV1/PYCARD/GPSM3/VAMP8/TNIP1 6 BP GO:0002755 MyD88-dependent toll-like receptor signaling pathway 2/117 24/18800 0.00969189159372777 0.139273740889088 0.122821373990234 TLR5/TNIP1 2 BP GO:0019985 translesion synthesis 2/117 24/18800 0.00969189159372777 0.139273740889088 0.122821373990234 MAD2L2/PARP10 2 BP GO:0035458 cellular response to interferon-beta 2/117 24/18800 0.00969189159372777 0.139273740889088 0.122821373990234 HTRA2/CDC34 2 BP GO:0060143 positive regulation of syncytium formation by plasma membrane fusion 2/117 24/18800 0.00969189159372777 0.139273740889088 0.122821373990234 CD53/EHD1 2 BP GO:0022409 positive regulation of cell-cell adhesion 6/117 291/18800 0.00976534566444879 0.139423935196292 0.122953825887186 LGALS1/FLOT2/VAV1/BAD/PYCARD/ITGB2 6 BP GO:2001235 positive regulation of apoptotic signaling pathway 4/117 134/18800 0.00984256711853094 0.139525306812569 0.123043222503629 HTRA2/BAD/PYCARD/UBB 4 BP GO:1901215 negative regulation of neuron death 5/117 209/18800 0.00993659732100181 0.139525306812569 0.123043222503629 DTNBP1/GBA/HTRA2/PINK1/BCL2L1 5 BP GO:0050878 regulation of body fluid levels 7/117 382/18800 0.0099615899125106 0.139525306812569 0.123043222503629 MTX1/DTNBP1/GBA/ILK/VAV1/FERMT3/VAMP8 7 BP GO:0002573 myeloid leukocyte differentiation 5/117 210/18800 0.0101295999274252 0.140986192700579 0.124331534362439 BATF/GPR137/GBA/FES/THOC5 5 BP GO:0043302 positive regulation of leukocyte degranulation 2/117 25/18800 0.0104921509574107 0.145119562929686 0.127976630756838 VAMP8/ITGB2 2 BP GO:0045786 negative regulation of cell cycle 7/117 387/18800 0.0106475676612888 0.146354454872249 0.129065645269888 MAD2L2/MUC1/AURKAIP1/RNF167/HTRA2/THOC5/CHMP2A 7 BP GO:0030833 regulation of actin filament polymerization 4/117 139/18800 0.0111489054983625 0.150609241754809 0.132817815403437 ARPC1B/ARPC4/PYCARD/TMSB10 4 BP GO:0051384 response to glucocorticoid 4/117 139/18800 0.0111489054983625 0.150609241754809 0.132817815403437 CFLAR/GBA/BAD/IGFBP7 4 BP GO:0031647 regulation of protein stability 6/117 300/18800 0.0112293379527987 0.150609241754809 0.132817815403437 GAPDH/FLOT2/DAD1/PYCARD/SERF2/PINK1 6 BP GO:0051047 positive regulation of secretion 6/117 300/18800 0.0112293379527987 0.150609241754809 0.132817815403437 DTNBP1/BAD/VAMP8/PINK1/CHMP2A/ITGB2 6 BP GO:0002534 cytokine production involved in inflammatory response 3/117 75/18800 0.0114609366769641 0.150791739681747 0.132978754902827 PYCARD/GPSM3/CUEDC2 3 BP GO:0061512 protein localization to cilium 3/117 75/18800 0.0114609366769641 0.150791739681747 0.132978754902827 DTNBP1/ATP6V1D/EHD1 3 BP GO:1900015 regulation of cytokine production involved in inflammatory response 3/117 75/18800 0.0114609366769641 0.150791739681747 0.132978754902827 PYCARD/GPSM3/CUEDC2 3 BP GO:0032970 regulation of actin filament-based process 7/117 393/18800 0.0115155011324967 0.150791739681747 0.132978754902827 ARPC1B/GMFG/ARPC4/FES/PYCARD/TMSB10/RAC2 7 BP GO:0006091 generation of precursor metabolites and energy 8/117 494/18800 0.0121030816195697 0.155608242522736 0.137226285650416 GAPDH/BLOC1S1/GALK1/COX6A1/GBA/PGAM1/PINK1/ACSS2 8 BP GO:0016540 protein autoprocessing 2/117 27/18800 0.0121770079925246 0.155608242522736 0.137226285650416 CASP4/HTRA2 2 BP GO:0070861 regulation of protein exit from endoplasmic reticulum 2/117 27/18800 0.0121770079925246 0.155608242522736 0.137226285650416 EDEM2/DERL2 2 BP GO:2001056 positive regulation of cysteine-type endopeptidase activity 4/117 143/18800 0.0122708710282964 0.155608242522736 0.137226285650416 CFLAR/HTRA2/BAD/PYCARD 4 BP GO:0016050 vesicle organization 6/117 306/18800 0.0122878016820844 0.155608242522736 0.137226285650416 BLOC1S1/HOOK2/DTNBP1/VAMP8/STX8/CHMP2A 6 BP GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process 3/117 77/18800 0.012305215744003 0.155608242522736 0.137226285650416 CFLAR/BAD/PYCARD 3 BP GO:0097191 extrinsic apoptotic signaling pathway 5/117 221/18800 0.012425146481764 0.156232097523544 0.137776444839656 CFLAR/HTRA2/BAD/PYCARD/BCL2L1 5 BP GO:0008088 axo-dendritic transport 3/117 78/18800 0.0127404017713003 0.158531204580179 0.139803959041859 BLOC1S1/FLOT2/DTNBP1 3 BP GO:0043254 regulation of protein-containing complex assembly 7/117 401/18800 0.012751267245943 0.158531204580179 0.139803959041859 ARPC1B/ARPC4/GBA/FES/PYCARD/TMSB10/PINK1 7 BP GO:0050870 positive regulation of T cell activation 5/117 223/18800 0.0128774211290961 0.159205212059719 0.140398346211962 LGALS1/FLOT2/VAV1/BAD/PYCARD 5 BP GO:0032438 melanosome organization 2/117 28/18800 0.0130608567187818 0.159688817230188 0.140824823242928 BLOC1S1/DTNBP1 2 BP GO:0090314 positive regulation of protein targeting to membrane 2/117 28/18800 0.0130608567187818 0.159688817230188 0.140824823242928 STOM/ITGB2 2 BP GO:0000082 G1/S transition of mitotic cell cycle 5/117 225/18800 0.0133407305674695 0.16221448761434 0.143052136912021 MUC1/TAF10/LSM10/TFDP1/CDC34 5 BP GO:2000377 regulation of reactive oxygen species metabolic process 4/117 147/18800 0.0134628198687483 0.162734998613433 0.143511160096703 CFLAR/PINK1/RAC2/ITGB2 4 BP GO:0001773 myeloid dendritic cell activation 2/117 29/18800 0.0139718254570954 0.162734998613433 0.143511160096703 BATF/PYCARD 2 BP GO:0030970 retrograde protein transport, ER to cytosol 2/117 29/18800 0.0139718254570954 0.162734998613433 0.143511160096703 EDEM2/DERL2 2 BP GO:0035521 monoubiquitinated histone deubiquitination 2/117 29/18800 0.0139718254570954 0.162734998613433 0.143511160096703 TAF10/TAF7 2 BP GO:0035522 monoubiquitinated histone H2A deubiquitination 2/117 29/18800 0.0139718254570954 0.162734998613433 0.143511160096703 TAF10/TAF7 2 BP GO:0048753 pigment granule organization 2/117 29/18800 0.0139718254570954 0.162734998613433 0.143511160096703 BLOC1S1/DTNBP1 2 BP GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 2/117 29/18800 0.0139718254570954 0.162734998613433 0.143511160096703 HTRA2/PINK1 2 BP GO:1903513 endoplasmic reticulum to cytosol transport 2/117 29/18800 0.0139718254570954 0.162734998613433 0.143511160096703 EDEM2/DERL2 2 BP GO:0006096 glycolytic process 3/117 81/18800 0.0140984513536797 0.163350119610959 0.144053617027953 GAPDH/GALK1/PGAM1 3 BP GO:0006605 protein targeting 6/117 317/18800 0.0144078111449153 0.165204591003614 0.145689020249102 STOM/HTRA2/TIMM17B/PINK1/RAC2/ITGB2 6 BP GO:0019058 viral life cycle 6/117 317/18800 0.0144078111449153 0.165204591003614 0.145689020249102 STOM/LGALS1/VAMP8/PARP10/TNIP1/CHMP2A 6 BP GO:2001234 negative regulation of apoptotic signaling pathway 5/117 230/18800 0.0145480286240501 0.165336153816396 0.145805041584702 CFLAR/MUC1/HTRA2/PINK1/BCL2L1 5 BP GO:0006757 ATP generation from ADP 3/117 82/18800 0.0145687076340701 0.165336153816396 0.145805041584702 GAPDH/GALK1/PGAM1 3 BP GO:0072593 reactive oxygen species metabolic process 5/117 231/18800 0.01479800403121 0.166564861832298 0.146888602676567 CFLAR/VAV1/PINK1/RAC2/ITGB2 5 BP GO:0051123 RNA polymerase II preinitiation complex assembly 2/117 30/18800 0.0149095484467326 0.166564861832298 0.146888602676567 TAF10/TAF7 2 BP GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage 2/117 30/18800 0.0149095484467326 0.166564861832298 0.146888602676567 MUC1/BCL2L1 2 BP GO:0045921 positive regulation of exocytosis 3/117 83/18800 0.0150477846741595 0.166564861832298 0.146888602676567 VAMP8/CHMP2A/ITGB2 3 BP GO:0016052 carbohydrate catabolic process 4/117 152/18800 0.0150533087964119 0.166564861832298 0.146888602676567 GAPDH/GALK1/BAD/PGAM1 4 BP GO:2001236 regulation of extrinsic apoptotic signaling pathway 4/117 153/18800 0.0153850204079259 0.169388309267364 0.149378517079312 CFLAR/HTRA2/PYCARD/BCL2L1 4 BP GO:0097194 execution phase of apoptosis 3/117 84/18800 0.0155357008055123 0.170200524171281 0.150094785270556 CFLAR/HTRA2/BCL2L1 3 BP GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors 2/117 31/18800 0.0158736633607562 0.172551844829648 0.152168345096757 CFLAR/BCL2L1 2 BP GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors 3/117 85/18800 0.0160324729253209 0.172551844829648 0.152168345096757 CFLAR/BAD/BCL2L1 3 BP GO:0072384 organelle transport along microtubule 3/117 85/18800 0.0160324729253209 0.172551844829648 0.152168345096757 BLOC1S1/DTNBP1/UBB 3 BP GO:0007034 vacuolar transport 4/117 155/18800 0.0160622142046577 0.172551844829648 0.152168345096757 HOOK2/PINK1/STX8/CHMP2A 4 BP GO:0002312 B cell activation involved in immune response 3/117 86/18800 0.0165381165183718 0.175209457081363 0.154512014378599 BATF/LGALS1/MAD2L2 3 BP GO:0033627 cell adhesion mediated by integrin 3/117 86/18800 0.0165381165183718 0.175209457081363 0.154512014378599 MUC1/FERMT3/ITGB2 3 BP GO:0010970 transport along microtubule 4/117 157/18800 0.0167578933528611 0.175209457081363 0.154512014378599 BLOC1S1/FLOT2/DTNBP1/UBB 4 BP GO:0031960 response to corticosteroid 4/117 157/18800 0.0167578933528611 0.175209457081363 0.154512014378599 CFLAR/GBA/BAD/IGFBP7 4 BP GO:0019082 viral protein processing 2/117 32/18800 0.0168638112780525 0.175209457081363 0.154512014378599 EDEM2/PARP10 2 BP GO:0035456 response to interferon-beta 2/117 32/18800 0.0168638112780525 0.175209457081363 0.154512014378599 HTRA2/CDC34 2 BP GO:1902253 regulation of intrinsic apoptotic signaling pathway by p53 class mediator 2/117 32/18800 0.0168638112780525 0.175209457081363 0.154512014378599 MUC1/UBB 2 BP GO:1901216 positive regulation of neuron death 3/117 87/18800 0.0170526456787687 0.175999320542184 0.155208571496283 BAD/CDC34/ITGB2 3 BP GO:0008064 regulation of actin polymerization or depolymerization 4/117 158/18800 0.0171127102943193 0.175999320542184 0.155208571496283 ARPC1B/ARPC4/PYCARD/TMSB10 4 BP GO:0052548 regulation of endopeptidase activity 7/117 426/18800 0.0172293174240746 0.175999320542184 0.155208571496283 GAPDH/CST7/MICAL1/CFLAR/HTRA2/BAD/PYCARD 7 BP GO:0051402 neuron apoptotic process 5/117 241/18800 0.0174578186468749 0.175999320542184 0.155208571496283 GAPDH/GBA/PINK1/CDC34/BCL2L1 5 BP GO:0030832 regulation of actin filament length 4/117 159/18800 0.0174722022812334 0.175999320542184 0.155208571496283 ARPC1B/ARPC4/PYCARD/TMSB10 4 BP GO:0050792 regulation of viral process 4/117 159/18800 0.0174722022812334 0.175999320542184 0.155208571496283 STOM/LGALS1/PARP10/TNIP1 4 BP GO:0000422 autophagy of mitochondrion 3/117 88/18800 0.0175760731314156 0.175999320542184 0.155208571496283 GBA/HTRA2/PINK1 3 BP GO:0061726 mitochondrion disassembly 3/117 88/18800 0.0175760731314156 0.175999320542184 0.155208571496283 GBA/HTRA2/PINK1 3 BP GO:0042060 wound healing 7/117 429/18800 0.0178328949334063 0.177766650845171 0.156767127579589 CFLAR/DTNBP1/ILK/VAV1/FERMT3/CD151/CHMP2A 7 BP GO:0016485 protein processing 5/117 243/18800 0.018025373685808 0.178879605231808 0.157748608985074 CASP4/CST7/HTRA2/BAD/PYCARD 5 BP GO:1903320 regulation of protein modification by small protein conjugation or removal 5/117 246/18800 0.0188994157502285 0.183647817090316 0.161953553350034 MAD2L2/PARP10/TNIP1/PINK1/UBB 5 BP GO:0000423 mitophagy 2/117 34/18800 0.0189207873007645 0.183647817090316 0.161953553350034 HTRA2/PINK1 2 BP GO:0006301 postreplication repair 2/117 34/18800 0.0189207873007645 0.183647817090316 0.161953553350034 MAD2L2/PARP10 2 BP GO:0035520 monoubiquitinated protein deubiquitination 2/117 34/18800 0.0189207873007645 0.183647817090316 0.161953553350034 TAF10/TAF7 2 BP GO:0090313 regulation of protein targeting to membrane 2/117 34/18800 0.0189207873007645 0.183647817090316 0.161953553350034 STOM/ITGB2 2 BP GO:0002446 neutrophil mediated immunity 2/117 35/18800 0.0199869143442571 0.191476369886757 0.168857321459342 ITGB2/PRAM1 2 BP GO:0019320 hexose catabolic process 2/117 35/18800 0.0199869143442571 0.191476369886757 0.168857321459342 GALK1/BAD 2 BP GO:0031646 positive regulation of nervous system process 2/117 35/18800 0.0199869143442571 0.191476369886757 0.168857321459342 CST7/GBA 2 BP GO:0050863 regulation of T cell activation 6/117 342/18800 0.0201498158449955 0.191609874556907 0.168975055261258 LGALS1/FLOT2/VAV1/BAD/PYCARD/RAC2 6 BP GO:0044772 mitotic cell cycle phase transition 7/117 440/18800 0.0201740175199997 0.191609874556907 0.168975055261258 MAD2L2/MUC1/TAF10/LSM10/CHMP2A/TFDP1/CDC34 7 BP GO:0032273 positive regulation of protein polymerization 3/117 93/18800 0.0203270369630579 0.192238174355757 0.169529134185827 FES/PYCARD/PINK1 3 BP GO:0032103 positive regulation of response to external stimulus 7/117 442/18800 0.0206217277451507 0.193803262280221 0.170909338724537 LGALS1/VAV1/PYCARD/GPSM3/VAMP8/TNIP1/RAC2 7 BP GO:1903037 regulation of leukocyte cell-cell adhesion 6/117 344/18800 0.0206676773150168 0.193803262280221 0.170909338724537 LGALS1/FLOT2/VAV1/BAD/PYCARD/ITGB2 6 BP GO:0030224 monocyte differentiation 2/117 36/18800 0.0210776722126914 0.195166897935925 0.172111888492974 FES/THOC5 2 BP GO:0042789 mRNA transcription by RNA polymerase II 2/117 36/18800 0.0210776722126914 0.195166897935925 0.172111888492974 TAF10/TAF7 2 BP GO:1903146 regulation of autophagy of mitochondrion 2/117 36/18800 0.0210776722126914 0.195166897935925 0.172111888492974 HTRA2/PINK1 2 BP GO:1903829 positive regulation of protein localization 7/117 446/18800 0.0215379257832679 0.198597623993216 0.175137343869205 STOM/EDEM2/HTRA2/BAD/PINK1/RAC2/ITGB2 7 BP GO:0044843 cell cycle G1/S phase transition 5/117 255/18800 0.0216879782688234 0.199151435306664 0.175625733611699 MUC1/TAF10/LSM10/TFDP1/CDC34 5 BP GO:0000731 DNA synthesis involved in DNA repair 2/117 37/18800 0.0221927186018005 0.200459127615447 0.176778948604675 MAD2L2/PARP10 2 BP GO:0014046 dopamine secretion 2/117 37/18800 0.0221927186018005 0.200459127615447 0.176778948604675 DTNBP1/PINK1 2 BP GO:0014059 regulation of dopamine secretion 2/117 37/18800 0.0221927186018005 0.200459127615447 0.176778948604675 DTNBP1/PINK1 2 BP GO:0045730 respiratory burst 2/117 37/18800 0.0221927186018005 0.200459127615447 0.176778948604675 PGAM1/RAC2 2 BP GO:0032535 regulation of cellular component size 6/117 351/18800 0.0225514370279293 0.20287126074312 0.178906137140697 ARPC1B/ARPC4/SLC12A9/VAV1/PYCARD/TMSB10 6 BP GO:0051090 regulation of DNA-binding transcription factor activity 7/117 452/18800 0.022964891537648 0.205281754541774 0.181031880001165 MAD2L2/CFLAR/FLOT2/PYCARD/PARP10/PINK1/TFDP1 7 BP GO:0051650 establishment of vesicle localization 4/117 173/18800 0.0230049142007953 0.205281754541774 0.181031880001165 BLOC1S1/DTNBP1/PINK1/CHMP2A 4 BP GO:0033363 secretory granule organization 2/117 38/18800 0.0233317144496747 0.205812400468343 0.18149984087726 BLOC1S1/DTNBP1 2 BP GO:1902229 regulation of intrinsic apoptotic signaling pathway in response to DNA damage 2/117 38/18800 0.0233317144496747 0.205812400468343 0.18149984087726 MUC1/BCL2L1 2 BP GO:0010950 positive regulation of endopeptidase activity 4/117 174/18800 0.0234363872200734 0.205812400468343 0.18149984087726 CFLAR/HTRA2/BAD/PYCARD 4 BP GO:0042770 signal transduction in response to DNA damage 4/117 174/18800 0.0234363872200734 0.205812400468343 0.18149984087726 BATF/MAD2L2/MUC1/THOC5 4 BP GO:0006165 nucleoside diphosphate phosphorylation 3/117 99/18800 0.0239233937813567 0.208805489162012 0.184139356865589 GAPDH/GALK1/PGAM1 3 BP GO:0010639 negative regulation of organelle organization 6/117 356/18800 0.0239659260041352 0.208805489162012 0.184139356865589 MAD2L2/GMFG/AURKAIP1/TMSB10/PINK1/BCL2L1 6 BP GO:0046365 monosaccharide catabolic process 2/117 39/18800 0.0244943239102316 0.210613467561326 0.18573375929731 GALK1/BAD 2 BP GO:1900016 negative regulation of cytokine production involved in inflammatory response 2/117 39/18800 0.0244943239102316 0.210613467561326 0.18573375929731 PYCARD/CUEDC2 2 BP GO:0019080 viral gene expression 3/117 100/18800 0.0245541231951298 0.210613467561326 0.18573375929731 EDEM2/MCTS1/PARP10 3 BP GO:0046939 nucleotide phosphorylation 3/117 100/18800 0.0245541231951298 0.210613467561326 0.18573375929731 GAPDH/GALK1/PGAM1 3 BP GO:0022411 cellular component disassembly 7/117 460/18800 0.0249678038326277 0.213334941627819 0.188133746416142 MICAL1/GBA/HTRA2/MCTS1/VAMP8/PINK1/CHMP2A 7 BP GO:0051091 positive regulation of DNA-binding transcription factor activity 5/117 265/18800 0.0250867280156343 0.213526650379226 0.18830280866796 CFLAR/FLOT2/PYCARD/PINK1/TFDP1 5 BP GO:0007007 inner mitochondrial membrane organization 2/117 40/18800 0.0256802143268857 0.216084845267673 0.190558804731023 MTX1/PINK1 2 BP GO:0016578 histone deubiquitination 2/117 40/18800 0.0256802143268857 0.216084845267673 0.190558804731023 TAF10/TAF7 2 BP GO:0051954 positive regulation of amine transport 2/117 40/18800 0.0256802143268857 0.216084845267673 0.190558804731023 DTNBP1/PINK1 2 BP GO:1903076 regulation of protein localization to plasma membrane 3/117 103/18800 0.0264999839068893 0.220542950264055 0.194490275068166 VAMP8/STX8/BCL2L1 3 BP GO:0009299 mRNA transcription 2/117 41/18800 0.0268890562064175 0.220542950264055 0.194490275068166 TAF10/TAF7 2 BP GO:0042119 neutrophil activation 2/117 41/18800 0.0268890562064175 0.220542950264055 0.194490275068166 ITGB2/PRAM1 2 BP GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter 2/117 41/18800 0.0268890562064175 0.220542950264055 0.194490275068166 TAF10/TAF7 2 BP GO:0071548 response to dexamethasone 2/117 41/18800 0.0268890562064175 0.220542950264055 0.194490275068166 CFLAR/GBA 2 BP GO:0051348 negative regulation of transferase activity 5/117 270/18800 0.0269076351429258 0.220542950264055 0.194490275068166 MAD2L2/DTNBP1/GBA/PYCARD/TAF7 5 BP GO:0110053 regulation of actin filament organization 5/117 270/18800 0.0269076351429258 0.220542950264055 0.194490275068166 ARPC1B/GMFG/ARPC4/PYCARD/TMSB10 5 BP GO:0018394 peptidyl-lysine acetylation 4/117 184/18800 0.0280227191004782 0.226293519367987 0.199561531100077 BLOC1S1/MUC1/TAF10/TAF7 4 BP GO:0045022 early endosome to late endosome transport 2/117 42/18800 0.0281205231930395 0.226293519367987 0.199561531100077 HOOK2/STX8 2 BP GO:0070266 necroptotic process 2/117 42/18800 0.0281205231930395 0.226293519367987 0.199561531100077 CFLAR/MLKL 2 BP GO:0070897 transcription preinitiation complex assembly 2/117 42/18800 0.0281205231930395 0.226293519367987 0.199561531100077 TAF10/TAF7 2 BP GO:2000249 regulation of actin cytoskeleton reorganization 2/117 42/18800 0.0281205231930395 0.226293519367987 0.199561531100077 GMFG/FES 2 BP GO:0006090 pyruvate metabolic process 3/117 106/18800 0.0285262291862669 0.227382268327305 0.200521666458403 GAPDH/GALK1/PGAM1 3 BP GO:0030593 neutrophil chemotaxis 3/117 106/18800 0.0285262291862669 0.227382268327305 0.200521666458403 VAV1/RAC2/ITGB2 3 BP GO:0051251 positive regulation of lymphocyte activation 6/117 371/18800 0.0285640626276506 0.227382268327305 0.200521666458403 LGALS1/MAD2L2/FLOT2/VAV1/BAD/PYCARD 6 BP GO:0033209 tumor necrosis factor-mediated signaling pathway 3/117 107/18800 0.0292194702347525 0.231765905482105 0.204387465818642 CASP4/ILK/PYCARD 3 BP GO:0051260 protein homooligomerization 4/117 187/18800 0.029495791675034 0.233122096345894 0.20558345024629 MLKL/PYCARD/CHMP2A/EHD1 4 BP GO:0051648 vesicle localization 4/117 189/18800 0.0305029627048188 0.240224400234035 0.211846761021667 BLOC1S1/DTNBP1/PINK1/CHMP2A 4 BP GO:2001239 regulation of extrinsic apoptotic signaling pathway in absence of ligand 2/117 44/18800 0.0306500425973299 0.240526752723018 0.212113396698207 HTRA2/BCL2L1 2 BP GO:0043433 negative regulation of DNA-binding transcription factor activity 4/117 190/18800 0.0310141056789407 0.242523730980551 0.213874472489329 MAD2L2/PYCARD/PARP10/TFDP1 4 BP GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress 2/117 45/18800 0.0319474577599125 0.24548515285655 0.216486062452039 HTRA2/PINK1 2 BP GO:0031295 T cell costimulation 2/117 45/18800 0.0319474577599125 0.24548515285655 0.216486062452039 LGALS1/VAV1 2 BP GO:0047496 vesicle transport along microtubule 2/117 45/18800 0.0319474577599125 0.24548515285655 0.216486062452039 BLOC1S1/DTNBP1 2 BP GO:0072583 clathrin-dependent endocytosis 2/117 45/18800 0.0319474577599125 0.24548515285655 0.216486062452039 CLTB/AP2S1 2 BP GO:0098927 vesicle-mediated transport between endosomal compartments 2/117 45/18800 0.0319474577599125 0.24548515285655 0.216486062452039 HOOK2/STX8 2 BP GO:0031532 actin cytoskeleton reorganization 3/117 111/18800 0.0320812780406146 0.245514505637236 0.216511947797196 GMFG/DTNBP1/FES 3 BP GO:0030098 lymphocyte differentiation 6/117 382/18800 0.032284103542899 0.245514505637236 0.216511947797196 BATF/LGALS1/GBA/VAV1/BAD/LYL1 6 BP GO:0042326 negative regulation of phosphorylation 6/117 382/18800 0.032284103542899 0.245514505637236 0.216511947797196 MICAL1/DTNBP1/GBA/PYCARD/DYNLL1/TAF7 6 BP GO:0050900 leukocyte migration 6/117 384/18800 0.0329928668252528 0.249553059446392 0.220073428408024 GBA/VAV1/PYCARD/GPSM3/RAC2/ITGB2 6 BP GO:0031640 killing of cells of another organism 2/117 46/18800 0.0332662234689044 0.249553059446392 0.220073428408024 GAPDH/BCL2L1 2 BP GO:0035307 positive regulation of protein dephosphorylation 2/117 46/18800 0.0332662234689044 0.249553059446392 0.220073428408024 GBA/PINK1 2 BP GO:0042168 heme metabolic process 2/117 46/18800 0.0332662234689044 0.249553059446392 0.220073428408024 BLVRA/UROD 2 BP GO:0022904 respiratory electron transport chain 3/117 113/18800 0.0335653045107456 0.250946009737433 0.22130182988237 COX6A1/GBA/PINK1 3 BP GO:0001774 microglial cell activation 2/117 47/18800 0.0346060286734776 0.254429041376764 0.224373411997298 CST7/ITGB2 2 BP GO:0031294 lymphocyte costimulation 2/117 47/18800 0.0346060286734776 0.254429041376764 0.224373411997298 LGALS1/VAV1 2 BP GO:0036230 granulocyte activation 2/117 47/18800 0.0346060286734776 0.254429041376764 0.224373411997298 ITGB2/PRAM1 2 BP GO:2000144 positive regulation of DNA-templated transcription, initiation 2/117 47/18800 0.0346060286734776 0.254429041376764 0.224373411997298 TAF10/TAF7 2 BP GO:2000378 negative regulation of reactive oxygen species metabolic process 2/117 47/18800 0.0346060286734776 0.254429041376764 0.224373411997298 CFLAR/PINK1 2 BP GO:0099111 microtubule-based transport 4/117 198/18800 0.0352853822977829 0.258564738493356 0.228020560404634 BLOC1S1/FLOT2/DTNBP1/UBB 4 BP GO:0030099 myeloid cell differentiation 6/117 391/18800 0.0355531940493024 0.259667387561406 0.228992953855851 BATF/GPR137/GBA/FES/THOC5/NBEAL2 6 BP GO:0032527 protein exit from endoplasmic reticulum 2/117 48/18800 0.0359665653086979 0.260111140614864 0.229384286488909 EDEM2/DERL2 2 BP GO:0033628 regulation of cell adhesion mediated by integrin 2/117 48/18800 0.0359665653086979 0.260111140614864 0.229384286488909 MUC1/FERMT3 2 BP GO:0045839 negative regulation of mitotic nuclear division 2/117 48/18800 0.0359665653086979 0.260111140614864 0.229384286488909 MAD2L2/AURKAIP1 2 BP GO:0002285 lymphocyte activation involved in immune response 4/117 201/18800 0.0369708888761017 0.265484076593145 0.234122519087541 BATF/LGALS1/MAD2L2/APBB1IP 4 BP GO:0008089 anterograde axonal transport 2/117 49/18800 0.0373475282709338 0.265484076593145 0.234122519087541 BLOC1S1/DTNBP1 2 BP GO:0060260 regulation of transcription initiation from RNA polymerase II promoter 2/117 49/18800 0.0373475282709338 0.265484076593145 0.234122519087541 TAF10/TAF7 2 BP GO:0097300 programmed necrotic cell death 2/117 49/18800 0.0373475282709338 0.265484076593145 0.234122519087541 CFLAR/MLKL 2 BP GO:0071346 cellular response to interferon-gamma 3/117 118/18800 0.0374292959317945 0.265484076593145 0.234122519087541 GAPDH/SLC26A6/STX8 3 BP GO:1904019 epithelial cell apoptotic process 3/117 118/18800 0.0374292959317945 0.265484076593145 0.234122519087541 CFLAR/BAD/BCL2L1 3 BP GO:0002269 leukocyte activation involved in inflammatory response 2/117 50/18800 0.0387486153934508 0.271362929954768 0.23930690519473 CST7/ITGB2 2 BP GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors 2/117 50/18800 0.0387486153934508 0.271362929954768 0.23930690519473 CFLAR/BCL2L1 2 BP GO:1903307 positive regulation of regulated secretory pathway 2/117 50/18800 0.0387486153934508 0.271362929954768 0.23930690519473 VAMP8/ITGB2 2 BP GO:2001238 positive regulation of extrinsic apoptotic signaling pathway 2/117 50/18800 0.0387486153934508 0.271362929954768 0.23930690519473 HTRA2/PYCARD 2 BP GO:0010948 negative regulation of cell cycle process 5/117 301/18800 0.0400740747910859 0.277797388079092 0.244981262634022 MAD2L2/MUC1/AURKAIP1/THOC5/CHMP2A 5 BP GO:0010823 negative regulation of mitochondrion organization 2/117 51/18800 0.0401695274221913 0.277797388079092 0.244981262634022 PINK1/BCL2L1 2 BP GO:0015872 dopamine transport 2/117 51/18800 0.0401695274221913 0.277797388079092 0.244981262634022 DTNBP1/PINK1 2 BP GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling 2/117 51/18800 0.0401695274221913 0.277797388079092 0.244981262634022 PYCARD/TNIP1 2 BP GO:0043523 regulation of neuron apoptotic process 4/117 207/18800 0.0404794651292561 0.278697931695011 0.245775425291959 GBA/PINK1/CDC34/BCL2L1 4 BP GO:0014902 myotube differentiation 3/117 122/18800 0.0406775562302253 0.278697931695011 0.245775425291959 CFLAR/CD53/EHD1 3 BP GO:0071901 negative regulation of protein serine/threonine kinase activity 3/117 122/18800 0.0406775562302253 0.278697931695011 0.245775425291959 DTNBP1/GBA/PYCARD 3 BP GO:0030100 regulation of endocytosis 4/117 208/18800 0.0410820793248031 0.279038967168833 0.246076174343481 DTNBP1/RAB4B/AP2S1/CD151 4 BP GO:0032355 response to estradiol 3/117 123/18800 0.0415112574767943 0.279038967168833 0.246076174343481 ARPC1B/CFLAR/BAD 3 BP GO:1901989 positive regulation of cell cycle phase transition 3/117 123/18800 0.0415112574767943 0.279038967168833 0.246076174343481 THOC5/LSM10/TFDP1 3 BP GO:0002204 somatic recombination of immunoglobulin genes involved in immune response 2/117 52/18800 0.0416099679917374 0.279038967168833 0.246076174343481 BATF/MAD2L2 2 BP GO:0002208 somatic diversification of immunoglobulins involved in immune response 2/117 52/18800 0.0416099679917374 0.279038967168833 0.246076174343481 BATF/MAD2L2 2 BP GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum 2/117 52/18800 0.0416099679917374 0.279038967168833 0.246076174343481 LMAN2/COPE 2 BP GO:0045190 isotype switching 2/117 52/18800 0.0416099679917374 0.279038967168833 0.246076174343481 BATF/MAD2L2 2 BP GO:1904375 regulation of protein localization to cell periphery 3/117 124/18800 0.0423535660826094 0.283167497706389 0.249717002757697 VAMP8/STX8/BCL2L1 3 BP GO:0006778 porphyrin-containing compound metabolic process 2/117 53/18800 0.0430696436014571 0.28536862661684 0.251658112943906 BLVRA/UROD 2 BP GO:0033059 cellular pigmentation 2/117 53/18800 0.0430696436014571 0.28536862661684 0.251658112943906 BLOC1S1/DTNBP1 2 BP GO:1900087 positive regulation of G1/S transition of mitotic cell cycle 2/117 53/18800 0.0430696436014571 0.28536862661684 0.251658112943906 LSM10/TFDP1 2 BP GO:0071496 cellular response to external stimulus 5/117 309/18800 0.0440104691316298 0.289956786260946 0.255704274610694 TLR5/GBA/FES/BAD/ASGR1 5 BP GO:0006469 negative regulation of protein kinase activity 4/117 213/18800 0.0441716855067441 0.289956786260946 0.255704274610694 DTNBP1/GBA/PYCARD/TAF7 4 BP GO:0031396 regulation of protein ubiquitination 4/117 213/18800 0.0441716855067441 0.289956786260946 0.255704274610694 MAD2L2/PARP10/PINK1/UBB 4 BP GO:0006909 phagocytosis 5/117 310/18800 0.0445183230863617 0.289956786260946 0.255704274610694 LMAN2/VAV1/PYCARD/RAC2/ITGB2 5 BP GO:0061900 glial cell activation 2/117 54/18800 0.0445482635918308 0.289956786260946 0.255704274610694 CST7/ITGB2 2 BP GO:1903202 negative regulation of oxidative stress-induced cell death 2/117 54/18800 0.0445482635918308 0.289956786260946 0.255704274610694 HTRA2/PINK1 2 BP GO:0031929 TOR signaling 3/117 128/18800 0.045808366783889 0.293918628782591 0.259198105816312 GPR137/GBA/PINK1 3 BP GO:0071621 granulocyte chemotaxis 3/117 128/18800 0.045808366783889 0.293918628782591 0.259198105816312 VAV1/RAC2/ITGB2 3 BP GO:1990266 neutrophil migration 3/117 128/18800 0.045808366783889 0.293918628782591 0.259198105816312 VAV1/RAC2/ITGB2 3 BP GO:0042743 hydrogen peroxide metabolic process 2/117 55/18800 0.0460455401209572 0.293918628782591 0.259198105816312 PINK1/RAC2 2 BP GO:0051784 negative regulation of nuclear division 2/117 55/18800 0.0460455401209572 0.293918628782591 0.259198105816312 MAD2L2/AURKAIP1 2 BP GO:0097352 autophagosome maturation 2/117 55/18800 0.0460455401209572 0.293918628782591 0.259198105816312 VAMP8/CHMP2A 2 BP GO:0006473 protein acetylation 4/117 216/18800 0.0460866534964117 0.293918628782591 0.259198105816312 BLOC1S1/MUC1/TAF10/TAF7 4 BP GO:0051604 protein maturation 5/117 314/18800 0.0465849859904388 0.296081173674494 0.261105189902971 CASP4/CST7/HTRA2/BAD/PYCARD 5 BP GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport 3/117 129/18800 0.046693325626931 0.296081173674494 0.261105189902971 LMAN2/TRAPPC1/COPE 3 BP GO:0050433 regulation of catecholamine secretion 2/117 56/18800 0.0475611881412385 0.299174542189587 0.263833139686301 DTNBP1/PINK1 2 BP GO:0051438 regulation of ubiquitin-protein transferase activity 2/117 56/18800 0.0475611881412385 0.299174542189587 0.263833139686301 MAD2L2/PINK1 2 BP GO:0030168 platelet activation 3/117 130/18800 0.0475867324223835 0.299174542189587 0.263833139686301 ILK/VAV1/FERMT3 3 BP GO:0034219 carbohydrate transmembrane transport 3/117 131/18800 0.0484885582729017 0.303483435356492 0.267633024544408 RAB4B/TMEM144/SLC26A6 3 BP GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway 2/117 57/18800 0.0490949253762422 0.303483435356492 0.267633024544408 CASP4/PYCARD 2 BP GO:0032784 regulation of DNA-templated transcription, elongation 2/117 57/18800 0.0490949253762422 0.303483435356492 0.267633024544408 THOC5/EAF2 2 BP GO:0045071 negative regulation of viral genome replication 2/117 57/18800 0.0490949253762422 0.303483435356492 0.267633024544408 PARP10/TNIP1 2 BP GO:0050432 catecholamine secretion 2/117 57/18800 0.0490949253762422 0.303483435356492 0.267633024544408 DTNBP1/PINK1 2 BP GO:2000142 regulation of DNA-templated transcription, initiation 2/117 57/18800 0.0490949253762422 0.303483435356492 0.267633024544408 TAF10/TAF7 2 BP GO:0007596 blood coagulation 4/117 221/18800 0.0493801261576663 0.304396153723999 0.268437923754034 DTNBP1/ILK/VAV1/FERMT3 4 CC GO:0070821 tertiary granule membrane 6/120 73/19594 5.66717829566465e-06 0.00172848938017772 0.00131239918425918 STOM/CD53/NBEAL2/VAMP8/DYNLL1/ITGB2 6 CC GO:0005765 lysosomal membrane 11/120 404/19594 3.88024986141547e-05 0.00372589133244248 0.00282897702549558 STOM/BLOC1S1/AP1S1/ATP6V0E1/GPR137/GBA/ATP6V1D/AP2S1/VAMP8/STX8/CHMP2A 11 CC GO:0098852 lytic vacuole membrane 11/120 404/19594 3.88024986141547e-05 0.00372589133244248 0.00282897702549558 STOM/BLOC1S1/AP1S1/ATP6V0E1/GPR137/GBA/ATP6V1D/AP2S1/VAMP8/STX8/CHMP2A 11 CC GO:0030139 endocytic vesicle 10/120 342/19594 4.88641486221964e-05 0.00372589133244248 0.00282897702549558 ATP6V0E1/FLOT2/CLTB/AP2S1/VAMP8/STX8/UBC/RAC2/EHD1/UBB 10 CC GO:0005774 vacuolar membrane 11/120 449/19594 9.98286077773086e-05 0.00608954507441583 0.00462364078126482 STOM/BLOC1S1/AP1S1/ATP6V0E1/GPR137/GBA/ATP6V1D/AP2S1/VAMP8/STX8/CHMP2A 11 CC GO:0030667 secretory granule membrane 9/120 312/19594 0.000130630292818809 0.00633928674307863 0.00481326344599586 STOM/CD53/FLOT2/ATP6V1D/RAB4B/NBEAL2/VAMP8/DYNLL1/ITGB2 9 CC GO:0030117 membrane coat 5/120 84/19594 0.000166276373588948 0.00633928674307863 0.00481326344599586 AP1S1/CLTB/AP2S1/COPE/CHMP2A 5 CC GO:0048475 coated membrane 5/120 84/19594 0.000166276373588948 0.00633928674307863 0.00481326344599586 AP1S1/CLTB/AP2S1/COPE/CHMP2A 5 CC GO:0035579 specific granule membrane 5/120 91/19594 0.000242090704986203 0.00800311668720996 0.00607656832160894 STOM/CD53/ATP6V1D/VAMP8/ITGB2 5 CC GO:0005741 mitochondrial outer membrane 7/120 205/19594 0.000271599743488981 0.00800311668720996 0.00607656832160894 MTX1/BAD/PINK1/UBC/RAC2/UBB/BCL2L1 7 CC GO:0030120 vesicle coat 4/120 52/19594 0.000288636995276425 0.00800311668720996 0.00607656832160894 AP1S1/CLTB/AP2S1/COPE 4 CC GO:0005766 primary lysosome 6/120 155/19594 0.000386934707960729 0.0090780835329248 0.00689276402845024 STOM/PLAC8/PYCARD/TRAPPC1/VAMP8/IMPDH1 6 CC GO:0042582 azurophil granule 6/120 155/19594 0.000386934707960729 0.0090780835329248 0.00689276402845024 STOM/PLAC8/PYCARD/TRAPPC1/VAMP8/IMPDH1 6 CC GO:0030125 clathrin vesicle coat 3/120 25/19594 0.000466940694414579 0.010172636556889 0.00772383103542913 AP1S1/CLTB/AP2S1 3 CC GO:0070820 tertiary granule 6/120 164/19594 0.000522074198543791 0.0106155087037237 0.00806009288979888 STOM/CD53/NBEAL2/VAMP8/DYNLL1/ITGB2 6 CC GO:0031968 organelle outer membrane 7/120 232/19594 0.000570917126896278 0.0107773284764194 0.00818295863610789 MTX1/BAD/PINK1/UBC/RAC2/UBB/BCL2L1 7 CC GO:0019867 outer membrane 7/120 234/19594 0.000600703554423375 0.0107773284764194 0.00818295863610789 MTX1/BAD/PINK1/UBC/RAC2/UBB/BCL2L1 7 CC GO:0005905 clathrin-coated pit 4/120 70/19594 0.000898185119101182 0.0152192478514367 0.011555598023524 AP1S1/CLTB/AP2S1/LRP10 4 CC GO:0101002 ficolin-1-rich granule 6/120 185/19594 0.000980022828960688 0.0157319454122637 0.0119448765856704 GMFG/PGAM1/NBEAL2/DYNLL1/IMPDH1/ITGB2 6 CC GO:0030666 endocytic vesicle membrane 6/120 194/19594 0.00125138445792902 0.0186784249384419 0.014182065527031 ATP6V0E1/AP2S1/VAMP8/UBC/RAC2/UBB 6 CC GO:0030055 cell-substrate junction 9/120 428/19594 0.00128605548756485 0.0186784249384419 0.014182065527031 ARPC1B/FLOT2/ILK/FES/FERMT3/CD151/RAC2/APBB1IP/ITGB2 9 CC GO:0030118 clathrin coat 3/120 39/19594 0.00174318672624827 0.0241669068866238 0.0183493339605081 AP1S1/CLTB/AP2S1 3 CC GO:0035578 azurophil granule lumen 4/120 91/19594 0.00237263221175371 0.0314631662862991 0.0238892030474057 PLAC8/PYCARD/TRAPPC1/IMPDH1 4 CC GO:0001931 uropod 2/120 13/19594 0.00277602492364725 0.0325649077581697 0.0247257280648743 PSTPIP1/FLOT2 2 CC GO:0030130 clathrin coat of trans-Golgi network vesicle 2/120 13/19594 0.00277602492364725 0.0325649077581697 0.0247257280648743 AP1S1/CLTB 2 CC GO:0031254 cell trailing edge 2/120 13/19594 0.00277602492364725 0.0325649077581697 0.0247257280648743 PSTPIP1/FLOT2 2 CC GO:0042581 specific granule 5/120 160/19594 0.00305800243584695 0.0327952120408918 0.0249005924037832 STOM/CD53/ATP6V1D/VAMP8/ITGB2 5 CC GO:0030132 clathrin coat of coated pit 2/120 14/19594 0.00322575856139919 0.0327952120408918 0.0249005924037832 CLTB/AP2S1 2 CC GO:0031082 BLOC complex 2/120 14/19594 0.00322575856139919 0.0327952120408918 0.0249005924037832 BLOC1S1/DTNBP1 2 CC GO:0033276 transcription factor TFTC complex 2/120 14/19594 0.00322575856139919 0.0327952120408918 0.0249005924037832 TAF10/TAF7 2 CC GO:0012510 trans-Golgi network transport vesicle membrane 2/120 15/19594 0.00370716826050737 0.0351381004046977 0.0266794895221173 AP1S1/CLTB 2 CC GO:0034774 secretory granule lumen 7/120 322/19594 0.00370746806243328 0.0351381004046977 0.0266794895221173 GMFG/PLAC8/PYCARD/TRAPPC1/FERMT3/PGAM1/IMPDH1 7 CC GO:0060205 cytoplasmic vesicle lumen 7/120 325/19594 0.00389983800402054 0.0351381004046977 0.0266794895221173 GMFG/PLAC8/PYCARD/TRAPPC1/FERMT3/PGAM1/IMPDH1 7 CC GO:0030660 Golgi-associated vesicle membrane 3/120 52/19594 0.0039790271168217 0.0351381004046977 0.0266794895221173 AP1S1/CLTB/COPE 3 CC GO:0031983 vesicle lumen 7/120 327/19594 0.00403224103004728 0.0351381004046977 0.0266794895221173 GMFG/PLAC8/PYCARD/TRAPPC1/FERMT3/PGAM1/IMPDH1 7 CC GO:0005925 focal adhesion 8/120 419/19594 0.00428694740885482 0.0360266036756008 0.0273541080539506 ARPC1B/FLOT2/ILK/FES/CD151/RAC2/APBB1IP/ITGB2 8 CC GO:0005775 vacuolar lumen 5/120 174/19594 0.00437044044589256 0.0360266036756008 0.0273541080539506 PLAC8/GBA/PYCARD/TRAPPC1/IMPDH1 5 CC GO:0030662 coated vesicle membrane 5/120 176/19594 0.00458618872583346 0.0368101989836633 0.0279490725674061 AP1S1/CLTB/AP2S1/VAMP8/COPE 5 CC GO:0030665 clathrin-coated vesicle membrane 4/120 111/19594 0.00484244915796338 0.0378704357225341 0.0287540840688784 AP1S1/CLTB/AP2S1/VAMP8 4 CC GO:0030131 clathrin adaptor complex 2/120 18/19594 0.00533748891440626 0.0397057102169246 0.0301475625460687 AP1S1/AP2S1 2 CC GO:0061702 inflammasome complex 2/120 18/19594 0.00533748891440626 0.0397057102169246 0.0301475625460687 CASP4/PYCARD 2 CC GO:0101003 ficolin-1-rich granule membrane 3/120 61/19594 0.0062268757760919 0.0452189788501912 0.0343336508957448 NBEAL2/DYNLL1/ITGB2 3 CC GO:0055037 recycling endosome 5/120 196/19594 0.00717792867209923 0.0509132149997736 0.0386571433993104 RAB4B/VAMP8/STX8/TUBA1A/EHD1 5 CC GO:0030027 lamellipodium 5/120 202/19594 0.00812169840970892 0.0562981367036641 0.0427457811037312 PSTPIP1/FLOT2/ILK/RAC2/APBB1IP 5 CC GO:0005868 cytoplasmic dynein complex 2/120 23/19594 0.00865174238829828 0.0586395872984661 0.0445235865596636 DYNLRB1/DYNLL1 2 CC GO:0030135 coated vesicle 6/120 290/19594 0.00894251565075198 0.0592927668147685 0.0450195295918864 AP1S1/LMAN2/CLTB/AP2S1/VAMP8/COPE 6 CC GO:0045335 phagocytic vesicle 4/120 138/19594 0.0103142080911487 0.0669326269744757 0.0508202862273845 ATP6V0E1/VAMP8/STX8/RAC2 4 CC GO:0005743 mitochondrial inner membrane 8/120 491/19594 0.0107283811881511 0.0681699221330432 0.0517597338024832 MTX1/COX6A1/MRPL51/AURKAIP1/TIMM17B/SLC25A20/PINK1/BCL2L1 8 CC GO:0015629 actin cytoskeleton 8/120 499/19594 0.0117408402494844 0.0706488049859944 0.0536418881688309 ARPC1B/MICAL1/PSTPIP1/FLOT2/ARPC4/ILK/FERMT3/RAC2 8 CC GO:0030670 phagocytic vesicle membrane 3/120 77/19594 0.0117940617166501 0.0706488049859944 0.0536418881688309 ATP6V0E1/VAMP8/RAC2 3 CC GO:0033176 proton-transporting V-type ATPase complex 2/120 27/19594 0.011813406735363 0.0706488049859944 0.0536418881688309 ATP6V0E1/ATP6V1D 2 CC GO:0005788 endoplasmic reticulum lumen 6/120 311/19594 0.0123203425726284 0.0722635477817628 0.0548679223882237 EDEM2/LGALS1/SHISA5/IGFBP7/NUCB1/P4HA1 6 CC GO:0090575 RNA polymerase II transcription regulator complex 5/120 230/19594 0.013677306608271 0.0787090285947671 0.0597618163618594 BATF/TAF10/RFXANK/TFDP1/TAF7 5 CC GO:0005758 mitochondrial intermembrane space 3/120 83/19594 0.0144285174337543 0.0802263358799394 0.0609138702108254 BLOC1S1/HTRA2/PINK1 3 CC GO:0030119 AP-type membrane coat adaptor complex 2/120 30/19594 0.014467044175071 0.0802263358799394 0.0609138702108254 AP1S1/AP2S1 2 CC GO:0005798 Golgi-associated vesicle 3/120 84/19594 0.014897352495326 0.0811373662691861 0.0616055930257841 AP1S1/CLTB/COPE 3 CC GO:0030140 trans-Golgi network transport vesicle 2/120 32/19594 0.0163653296438633 0.087568869146988 0.0664888738993524 AP1S1/CLTB 2 CC GO:0032592 integral component of mitochondrial membrane 3/120 88/19594 0.0168583997534673 0.0882983182027479 0.0670427265042435 MTX1/TIMM17B/PINK1 3 CC GO:0005669 transcription factor TFIID complex 2/120 33/19594 0.0173521993576263 0.0882983182027479 0.0670427265042435 TAF10/TAF7 2 CC GO:0120111 neuron projection cytoplasm 3/120 89/19594 0.0173701609579176 0.0882983182027479 0.0670427265042435 BLOC1S1/FLOT2/DTNBP1 3 CC GO:0098573 intrinsic component of mitochondrial membrane 3/120 90/19594 0.0178905464379964 0.0894527321899821 0.0679192444583126 MTX1/TIMM17B/PINK1 3 CC GO:0045334 clathrin-coated endocytic vesicle 3/120 91/19594 0.0184195662411638 0.0906123823154025 0.0687997380824454 CLTB/AP2S1/VAMP8 3 CC GO:0031970 organelle envelope lumen 3/120 93/19594 0.0195035428597066 0.0944219138446113 0.0716922210381863 BLOC1S1/HTRA2/PINK1 3 CC GO:0070461 SAGA-type complex 2/120 36/19594 0.0204596772670351 0.0975031494757144 0.0740317269530877 TAF10/TAF7 2 CC GO:0005802 trans-Golgi network 5/120 260/19594 0.0219964382458078 0.103214056384175 0.078367877151056 AP1S1/HOOK2/GBA/CLTB/STX8 5 CC GO:0030672 synaptic vesicle membrane 3/120 103/19594 0.0254433112713097 0.115824028921634 0.0879423170414476 DTNBP1/CLTB/BCL2L1 3 CC GO:0099501 exocytic vesicle membrane 3/120 103/19594 0.0254433112713097 0.115824028921634 0.0879423170414476 DTNBP1/CLTB/BCL2L1 3 CC GO:0098636 protein complex involved in cell adhesion 2/120 43/19594 0.028525284899308 0.127944292563073 0.0971449330936186 LGALS1/ITGB2 2 CC GO:0005770 late endosome 5/120 283/19594 0.0302261025379452 0.132896224262411 0.100904812209596 CST7/DERL2/VAMP8/STX8/CHMP2A 5 CC GO:0030136 clathrin-coated vesicle 4/120 192/19594 0.030500772781537 0.132896224262411 0.100904812209596 AP1S1/CLTB/AP2S1/VAMP8 4 CC GO:0008021 synaptic vesicle 4/120 196/19594 0.032541940244645 0.13979284189601 0.106141243199732 DTNBP1/CLTB/RABAC1/BCL2L1 4 CC GO:0097542 ciliary tip 2/120 47/19594 0.0336140094718297 0.142392679012612 0.108115235143312 DYNLRB1/DYNLL1 2 CC GO:0031201 SNARE complex 2/120 48/19594 0.0349376708337069 0.145972460332611 0.110833274454441 VAMP8/STX8 2 CC GO:0030496 midbody 4/120 203/19594 0.036302880691862 0.149112160422357 0.113217170985051 MICAL1/DTNBP1/EXOC6/CHMP2A 4 CC GO:0030133 transport vesicle 6/120 402/19594 0.0373548763052902 0.149112160422357 0.113217170985051 AP1S1/DTNBP1/CLTB/RABAC1/COPE/BCL2L1 6 CC GO:0030658 transport vesicle membrane 4/120 205/19594 0.0374217443931817 0.149112160422357 0.113217170985051 AP1S1/DTNBP1/CLTB/BCL2L1 4 CC GO:0016469 proton-transporting two-sector ATPase complex 2/120 50/19594 0.0376447093525295 0.149112160422357 0.113217170985051 ATP6V0E1/ATP6V1D 2 CC GO:1904813 ficolin-1-rich granule lumen 3/120 124/19594 0.0407209903267795 0.159229513457279 0.120899026611221 GMFG/PGAM1/IMPDH1 3 CC GO:0140534 endoplasmic reticulum protein-containing complex 3/120 125/19594 0.0415417981896478 0.159554059765472 0.12114544658638 DERL2/DAD1/P4HA1 3 CC GO:0031312 extrinsic component of organelle membrane 2/120 53/19594 0.041850245184386 0.159554059765472 0.12114544658638 UBC/UBB 2 CC GO:0070382 exocytic vesicle 4/120 214/19594 0.04270099141905 0.160787683738398 0.122082106721131 DTNBP1/CLTB/RABAC1/BCL2L1 4 CC GO:0030286 dynein complex 2/120 54/19594 0.0432896206011007 0.161016271747997 0.122255667936356 DYNLRB1/DYNLL1 2 CC GO:0031305 integral component of mitochondrial inner membrane 2/120 56/19594 0.0462230027966779 0.169855612686587 0.128967160624846 MTX1/TIMM17B 2 CC GO:0031304 intrinsic component of mitochondrial inner membrane 2/120 57/19594 0.0477164642042606 0.173256209313089 0.131549149435305 MTX1/TIMM17B 2 CC GO:0035577 azurophil granule membrane 2/120 58/19594 0.049227413248939 0.176639541657958 0.13411802990423 STOM/VAMP8 2 MF GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process 3/120 15/18410 0.000116055363644022 0.0337721108204103 0.0317625205762586 CASP4/CFLAR/PYCARD 3 MF GO:0019869 chloride channel inhibitor activity 2/120 10/18410 0.00183232783499016 0.129784798002647 0.122062027421552 VAMP8/STX8 2 MF GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway 2/120 10/18410 0.00183232783499016 0.129784798002647 0.122062027421552 CASP4/CFLAR 2 MF GO:0002020 protease binding 5/120 136/18410 0.00197510698266786 0.129784798002647 0.122062027421552 CFLAR/DERL2/PYCARD/PINK1/UBC 5 MF GO:0043422 protein kinase B binding 2/120 11/18410 0.00222997934712451 0.129784798002647 0.122062027421552 BAD/PINK1 2 MF GO:0016504 peptidase activator activity 3/120 43/18410 0.00275621535378141 0.130354333574552 0.122597673103214 BAD/PYCARD/PINK1 3 MF GO:0031386 protein tag 2/120 13/18410 0.00313567125437066 0.130354333574552 0.122597673103214 UBC/UBB 2 MF GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 2/120 17/18410 0.00537503868518421 0.173792917487623 0.163451468789227 BAD/PYCARD 2 MF GO:0017081 chloride channel regulator activity 2/120 17/18410 0.00537503868518421 0.173792917487623 0.163451468789227 VAMP8/STX8 2 MF GO:0035615 clathrin adaptor activity 2/120 18/18410 0.00602127069188464 0.175218977133843 0.164792671567369 AP1S1/AP2S1 2 MF GO:0140312 cargo adaptor activity 2/120 19/18410 0.00670112634020997 0.177275251363736 0.16672658836886 AP1S1/AP2S1 2 MF GO:0016505 peptidase activator activity involved in apoptotic process 2/120 20/18410 0.00741414733168262 0.179793072793304 0.169094588266446 BAD/PYCARD 2 MF GO:0030276 clathrin binding 3/120 69/18410 0.0103538026344213 0.231765889739739 0.217974792303607 AP1S1/CLTB/AP2S1 3 MF GO:0048029 monosaccharide binding 3/120 71/18410 0.0111892749951029 0.232577073112495 0.218737706671184 GALK1/LMAN2/P4HA1 3 MF GO:0051959 dynein light intermediate chain binding 2/120 27/18410 0.0132963537164821 0.255267679778418 0.240078121694298 HOOK2/DYNLL1 2 MF GO:0016798 hydrolase activity, acting on glycosyl bonds 4/120 144/18410 0.0146630016381555 0.255267679778418 0.240078121694298 TLR5/EDEM2/GBA/LYG1 4 MF GO:0038024 cargo receptor activity 3/120 79/18410 0.0149125448667804 0.255267679778418 0.240078121694298 LRP10/ASGR1/ITGB2 3 MF GO:0140318 protein transporter activity 2/120 31/18410 0.0173196060539945 0.266953969169337 0.251069025082393 RHBDF2/TIMM17B 2 MF GO:0061134 peptidase regulator activity 5/120 230/18410 0.0174299842412969 0.266953969169337 0.251069025082393 GAPDH/CST7/BAD/PYCARD/PINK1 5 MF GO:0005484 SNAP receptor activity 2/120 36/18410 0.0229758490444697 0.308257161721619 0.289914494655891 VAMP8/STX8 2 MF GO:0045505 dynein intermediate chain binding 2/120 36/18410 0.0229758490444697 0.308257161721619 0.289914494655891 DYNLRB1/DYNLL1 2 MF GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 3/120 94/18410 0.023570361300669 0.308257161721619 0.289914494655891 EDEM2/GBA/LYG1 3 MF GO:0003779 actin binding 7/120 439/18410 0.0249370738880685 0.308257161721619 0.289914494655891 ARPC1B/MICAL1/GMFG/PSTPIP1/ARPC4/MSRB2/TMSB10 7 MF GO:0016251 RNA polymerase II general transcription initiation factor activity 2/120 38/18410 0.0254232710698243 0.308257161721619 0.289914494655891 TAF10/TAF7 2 MF GO:0061650 ubiquitin-like protein conjugating enzyme activity 2/120 39/18410 0.0266850666559185 0.310614175874891 0.292131256022686 UBE2F/CDC34 2 MF GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 2/120 40/18410 0.0279717493831088 0.313068425787871 0.294439467190619 BAD/PYCARD 2 MF GO:0005200 structural constituent of cytoskeleton 3/120 104/18410 0.0305683278948753 0.329458645089211 0.3098543958155 ARPC1B/ARPC4/TUBA1A 3 MF GO:0030246 carbohydrate binding 5/120 270/18410 0.031949708711436 0.332048758393853 0.312290385901254 LGALS1/GALK1/LMAN2/ASGR1/P4HA1 5 MF GO:0140223 general transcription initiation factor activity 2/120 45/18410 0.0347655718091266 0.34885453091227 0.328096140485405 TAF10/TAF7 2 MF GO:0004197 cysteine-type endopeptidase activity 3/120 120/18410 0.0437806283376345 0.424672094875054 0.399402223431051 CASP4/CFLAR/PYCARD 3 MF GO:0030674 protein-macromolecule adaptor activity 5/120 305/18410 0.0495025765426792 0.431559861301459 0.405880137234145 AP1S1/ARPC4/AP2S1/VAMP8/STX8 5