,Locus Id,NCBI Accession number,NCBI gi number,First base pair in the CDS,Last base pair in the CDS,Gene length,Direction of CDS,Gene description,Fraction GC,Number of TA pairs,Uncorrected replicate 1 p value,Bonferroni corrected replicate 1 p value,Number of transposon insertions seen in replicate 1,Uncorrected replicate 2 p value,Bonferroni corrected replicate 2 p value,Number of transposon insertions seen in replicate 2,Is the gene essential?
0,HNEAP_RS00015,WP_041600463.1,753844846.0,159,1559,1400.0,+,chromosomal replication initiator protein DnaA,0.5353,30,4.1246908253787406e-22,9.932255507512008e-19,2.0,2.2044575363058986e-21,5.308333747424604e-18,2.0,essential
1,HNEAP_RS00020,WP_012822905.1,502585110.0,1623,2735,1112.0,+,DNA polymerase III subunit beta,0.5346,22,3.05118707645653e-17,7.347258480107325e-14,2.0,1.1407391721267438e-16,2.746899926481199e-13,2.0,essential
2,HNEAP_RS00025,WP_041600303.1,753844686.0,2815,3840,1025.0,+,DNA replication and repair protein RecF,0.5536,16,0.999932734665786,2407.838025075213,66.0,0.9999143702163883,2407.793803481063,64.0,nonessential
3,HNEAP_RS00030,WP_012822907.1,502585112.0,4029,6482,2453.0,+,DNA topoisomerase (ATP-hydrolyzing) subunit B,0.5534,49,7.192812458363274e-44,1.7320292399738763e-40,0.0,1.5128648102997184e-42,3.6429784632017216e-39,0.0,essential
4,HNEAP_RS00035,WP_012822908.1,502585113.0,6658,7233,575.0,+,LemA family protein,0.533,16,0.999964366385369,2407.9141942559686,43.0,0.9997002335221541,2407.278162321347,39.0,nonessential
5,HNEAP_RS00040,WP_012822909.1,502585114.0,7248,8171,923.0,+,hypothetical protein,0.539,22,0.9996936716191476,2407.2623612589073,58.0,0.9998580084984331,2407.6580844642267,58.0,nonessential
6,HNEAP_RS00045,WP_012822910.1,502585115.0,8681,9454,773.0,+,exodeoxyribonuclease III,0.5103,26,0.9878855205942845,2378.828333591037,43.0,0.9883955186821456,2380.0564089866066,42.0,nonessential
7,HNEAP_RS00050,WP_012822911.1,502585116.0,9655,12165,2510.0,-,ABC transporter permease,0.5707,48,0.963644949281974,2320.457037870993,117.0,0.9655562765345737,2325.0595138952535,114.0,nonessential
8,HNEAP_RS00055,WP_049772428.1,908628395.0,12156,12896,740.0,-,ABC transporter,0.5789,10,0.9999951763055287,2407.988384543713,55.0,0.9999916049141883,2407.9797846333654,53.0,nonessential
9,HNEAP_RS00060,WP_012822913.1,502585118.0,13056,13742,686.0,+,arylesterase,0.5546,16,0.9999999037932874,2407.9997683342363,57.0,0.9999999185293535,2407.999803818683,56.0,nonessential
10,HNEAP_RS00065,WP_012822914.1,502585119.0,14129,14500,371.0,-,DUF559 domain-containing protein,0.5188,9,0.9958756842840486,2398.068647755989,25.0,0.9945868129917154,2394.9650456840504,24.0,nonessential
11,HNEAP_RS00070,WP_012822915.1,502585120.0,14569,15519,950.0,-,IS110 family transposase,0.5741,13,0.9999999999999692,2407.999999999926,90.0,0.9999999999999009,2407.9999999997613,87.0,nonessential
12,HNEAP_RS00075,WP_012822917.1,502585122.0,16642,17178,536.0,-,prepilin-type cleavage/methylation domain-containing protein,0.5047,11,0.20468007453631717,492.86961948345174,17.0,0.17763783870012384,427.7519155898982,16.0,nonessential
13,HNEAP_RS00080,WP_012822918.1,502585123.0,17753,18331,578.0,+,Tfp pilus assembly protein FimT-like protein,0.5268,23,0.9999998503874171,2407.9996397329005,50.0,0.9999907604339561,2407.9777511249663,44.0,nonessential
14,HNEAP_RS00085,WP_012822919.1,502585124.0,18315,18794,479.0,+,type IV pilus modification protein PilV,0.5792,12,0.9305738973833024,2240.821944898992,25.0,0.88288020778504,2125.9755403463764,23.0,nonessential
15,HNEAP_RS00090,WP_012822920.1,502585125.0,18791,19822,1031.0,+,prepilin-type cleavage/methylation domain-containing protein,0.5407,35,0.9999203313540677,2407.808157900595,66.0,0.9979742835529712,2403.122074795555,58.0,nonessential
16,HNEAP_RS00095,WP_081441062.1,1174219881.0,19825,20643,818.0,+,hypothetical protein,0.5495,15,0.5134828656414041,1236.466740464501,32.0,0.5119795954938711,1232.8468659492414,31.0,nonessential
17,HNEAP_RS00100,WP_012822922.1,502585127.0,20656,24519,3863.0,+,type 4 fimbrial biogenesis protein PilY1,0.5005,173,0.9999999999999999,2407.9999999999995,274.0,0.9999999999999999,2407.9999999999995,262.0,nonessential
18,HNEAP_RS00105,WP_012822923.1,502585128.0,24658,25152,494.0,+,PilE protein,0.5394,19,0.9999998728114703,2407.9996937300207,45.0,0.9999999465624202,2407.9998713223076,45.0,nonessential
19,HNEAP_RS00110,WP_012822924.1,502585130.0,25490,26074,584.0,+,pilus assembly protein,0.5556,9,0.9976311034222265,2402.2956970407213,37.0,0.9985902222029458,2404.6052550646937,37.0,nonessential
20,HNEAP_RS00115,WP_012822925.1,502585131.0,26258,26629,371.0,+,DUF559 domain-containing protein,0.4946,11,0.07516227890141101,180.9907675945977,9.0,0.050725100828833775,122.14604279583173,8.0,nonessential
21,HNEAP_RS00120,WP_012822927.1,502585133.0,26886,29708,2822.0,-,excinuclease ABC subunit UvrA,0.5912,48,0.8208266388500045,1976.550546350811,121.0,0.6871325738593408,1654.6152378532927,113.0,nonessential
22,HNEAP_RS00125,WP_012822928.1,502585134.0,29824,30381,557.0,+,single-stranded DNA-binding protein,0.5914,11,4.281928176545009e-05,0.10310883049120381,6.0,1.8330557343315856e-05,0.04413998208270458,5.0,ambiguous
23,HNEAP_RS00130,WP_012822929.1,502585135.0,30592,32391,1799.0,-,gamma-glutamyltransferase,0.5767,34,0.9999999999989695,2407.9999999975184,136.0,0.9999999999957478,2407.999999989761,131.0,nonessential
24,HNEAP_RS00135,WP_012822930.1,502585136.0,32408,33346,938.0,-,23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ,0.5634,27,0.9999719688222672,2407.9325009240197,63.0,0.9999303662443342,2407.8323219163567,60.0,nonessential
25,HNEAP_RS00140,WP_012822931.1,502585137.0,33737,34285,548.0,+,metallophosphoesterase,0.5974,8,0.9954542918208757,2397.053934704669,34.0,0.9984296945228398,2404.2187044109983,35.0,nonessential
26,HNEAP_RS00145,WP_012822932.1,502585138.0,34356,35618,1262.0,+,ketohexokinase,0.5764,22,0.999997352549531,2407.993624939271,84.0,0.9999567326518641,2407.895812225689,77.0,nonessential
27,HNEAP_RS00150,WP_012822933.1,502585139.0,35755,38121,2366.0,+,GGDEF domain-containing protein,0.5758,27,0.9999921552069254,2407.9811097382762,137.0,0.9999899361111558,2407.975766155663,133.0,nonessential
28,HNEAP_RS00155,WP_012822934.1,502585140.0,38154,38462,308.0,+,BolA family transcriptional regulator,0.5793,4,0.8320705648670255,2003.6259201997973,15.0,0.8589381732857772,2068.323121272151,15.0,nonessential
29,HNEAP_RS00160,WP_012822935.1,502585141.0,38491,39528,1037.0,+,HDOD domain-containing protein,0.5694,17,0.4680286334117149,1127.0129492554095,40.0,0.5470849815897351,1317.380635668082,40.0,nonessential
30,HNEAP_RS00165,WP_012822936.1,502585142.0,39572,41770,2198.0,-,bifunctional (p)ppGpp synthetase/guanosine-3' 5'-bis(diphosphate) 3'-pyrophosphohydrolase,0.5789,30,5.671204438665351e-13,1.3656260288306165e-09,30.0,1.2021720902583739e-13,2.894830393342164e-10,27.0,essential
31,HNEAP_RS00170,WP_012822937.1,502585143.0,41772,42095,323.0,-,DNA-directed RNA polymerase subunit omega,0.5772,3,0.05579299832696444,134.34953997133036,7.0,0.06837665721811485,164.65099058122055,7.0,nonessential
32,HNEAP_RS00175,WP_012822938.1,502585144.0,42146,42775,629.0,-,guanylate kinase,0.5794,9,8.653969717934253e-12,2.083875908078568e-08,0.0,1.8898819733406782e-11,4.550835791804353e-08,0.0,essential
33,HNEAP_RS00180,WP_012822939.1,502585145.0,42782,43396,614.0,-,DedA family protein,0.5707,11,0.8946705050949242,2154.3665762685773,30.0,0.8462773971293702,2037.8359722875234,28.0,nonessential
34,HNEAP_RS00185,WP_012822940.1,502585146.0,43484,43954,470.0,-,glycine zipper 2TM domain-containing protein,0.6178,11,0.9999634205545669,2407.911916695397,37.0,0.9999808625081664,2407.9539169196646,37.0,nonessential
35,HNEAP_RS00190,WP_012822941.1,502585147.0,44187,44936,749.0,+,membrane protein,0.5427,18,3.6460022719070175e-10,8.779573470752098e-07,3.0,8.428772472484245e-10,2.029648411374206e-06,3.0,essential
36,HNEAP_RS00195,WP_012822942.1,502585148.0,44946,45716,770.0,-,exodeoxyribonuclease III,0.5551,17,0.50691484724787,1220.6509521728708,30.0,0.574904920627717,1384.3710488715426,30.0,nonessential
37,HNEAP_RS00200,WP_041600478.1,753844861.0,46091,47482,1391.0,-,hypothetical protein,0.5338,27,0.7268667817538201,1750.2952104631988,59.0,0.7142387112529963,1719.8868166972152,57.0,nonessential
38,HNEAP_RS00205,WP_081441063.1,1174219882.0,48094,50388,2294.0,+,hypothetical protein,0.5712,60,0.9999999999999938,2407.999999999985,171.0,0.9999999999999991,2407.9999999999977,170.0,nonessential
39,HNEAP_RS00210,WP_012822946.1,502585152.0,50405,51196,791.0,-,TIGR01458 family HAD-type hydrolase,0.5934,13,0.999983488819831,2407.960241078153,56.0,0.9999733082097038,2407.9357261689665,54.0,nonessential
40,HNEAP_RS00215,WP_012822947.1,502585153.0,51408,52196,788.0,-,competence/damage-inducible protein A,0.5805,10,0.9999995634595247,2407.9989488105352,61.0,0.9999996591185446,2407.9991791574553,60.0,nonessential
41,HNEAP_RS00220,WP_012822948.1,502585154.0,52193,53305,1112.0,-,ferrochelatase,0.5732,27,4.0991846315237596e-13,9.870836592709214e-10,6.0,1.7876547004628826e-13,4.3046725187146213e-10,5.0,essential
42,HNEAP_RS00225,WP_012822949.1,502585155.0,53431,54390,959.0,+,thioredoxin-disulfide reductase,0.5594,13,1.358972651620654e-17,3.2724061451025346e-14,0.0,4.4709398219400884e-17,1.0766023091231732e-13,0.0,essential
43,HNEAP_RS00230,WP_012822950.1,502585156.0,54484,54804,320.0,+,hypothetical protein,0.6012,4,0.9678675653444477,2330.6250973494302,19.0,0.9755592832367852,2349.1467540341787,19.0,nonessential
44,HNEAP_RS00235,WP_012822951.1,502585157.0,54801,55673,872.0,+,hypothetical protein,0.6174,14,0.9999999166372723,2407.9997992625517,68.0,0.9999999418687959,2407.9998600200606,67.0,nonessential
45,HNEAP_RS00240,WP_012822952.1,502585158.0,55687,56304,617.0,-,5'-deoxynucleotidase,0.5485,12,0.275506747198851,663.4202472548332,21.0,0.2536607907569922,610.8151841428372,20.0,nonessential
46,HNEAP_RS00245,WP_012822953.1,502585159.0,56333,57763,1430.0,-,deoxyguanosinetriphosphate triphosphohydrolase,0.5947,16,0.9963913489821341,2399.310368348979,77.0,0.9963816035122246,2399.286901257437,75.0,nonessential
47,HNEAP_RS00250,WP_012822954.1,502585160.0,57863,58720,857.0,+,NAD(P)-dependent oxidoreductase,0.6131,5,0.9999935132763954,2407.98437996956,61.0,0.9999949719877603,2407.987892546527,60.0,nonessential
48,HNEAP_RS00255,WP_012822955.1,502585161.0,58846,60408,1562.0,+,bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH,0.6065,19,3.3706317186257887e-28,8.1164811784508995e-25,0.0,2.3447521251210183e-27,5.646163117291412e-24,0.0,essential
49,HNEAP_RS00260,WP_012822956.1,502585162.0,60466,62061,1595.0,+,DNA recombination protein RmuC,0.5977,18,0.9954622918678522,2397.073198817788,84.0,0.9970254065301537,2400.8371789246103,83.0,nonessential
50,HNEAP_RS00265,WP_012822957.1,502585163.0,62045,62242,197.0,-,hypothetical protein,0.5101,0,0.2028471830892292,488.4560168788639,5.0,0.2270390937117781,546.7101376579617,5.0,nonessential
51,HNEAP_RS00270,WP_012822958.1,502585164.0,62254,63108,854.0,-,metallophosphoesterase,0.5333,22,0.6202606225414429,1493.5875790797945,35.0,0.7456344992133018,1795.487874105631,36.0,nonessential
52,HNEAP_RS00275,WP_012822959.1,502585165.0,63522,63998,476.0,+,hypothetical protein,0.499,14,0.3843991797292737,925.6332247880911,17.0,0.531383177584035,1279.5706916223562,18.0,nonessential
53,HNEAP_RS00280,WP_012822960.1,502585166.0,64169,64549,380.0,+,hypothetical protein,0.5249,9,0.5595692886020251,1347.4428469536765,15.0,0.6068790100803254,1461.3646562734236,15.0,nonessential
54,HNEAP_RS00285,WP_081441064.1,1174219883.0,64607,67444,2837.0,+,bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase,0.5648,41,0.6854531902671444,1650.5712821632835,117.0,0.5558796206541846,1338.5581265352766,110.0,nonessential
55,HNEAP_RS00290,WP_012822962.1,502585168.0,67499,67957,458.0,+,hypothetical protein,0.5882,6,0.994247819808227,2394.1487500982107,29.0,0.9879548330681669,2378.995238028146,27.0,nonessential
56,HNEAP_RS00295,WP_012822963.1,502585169.0,68056,68586,530.0,+,molecular chaperone Skp,0.5593,10,0.9999999904500528,2407.999977003727,50.0,0.9999999903749393,2407.9999768228536,49.0,nonessential
57,HNEAP_RS00300,WP_012822964.1,502585170.0,68944,69192,248.0,+,phosphopantetheine-binding protein,0.5141,4,0.34645554788066857,834.2649592966499,8.0,0.38235284551251864,920.7056519941449,8.0,nonessential
58,HNEAP_RS00305,WP_012822965.1,502585171.0,69189,70436,1247.0,+,3-oxoacyl-ACP synthase,0.625,16,0.9999999999999967,2407.999999999992,111.0,0.9999999999999973,2407.9999999999936,109.0,nonessential
59,HNEAP_RS00310,WP_012822966.1,502585172.0,70516,70800,284.0,+,acyl carrier protein,0.5123,3,0.6603289142992348,1590.0720256325574,12.0,0.6983558831137529,1681.640966537917,12.0,nonessential
60,HNEAP_RS12050,WP_012822967.1,502585173.0,70809,71507,698.0,+,membrane protein-like protein,0.5851,15,0.990721182325493,2385.656607039787,40.0,0.9942735003450649,2394.210588830916,40.0,nonessential
61,HNEAP_RS00320,WP_012822968.1,502585174.0,71516,73297,1781.0,+,AMP-dependent synthetase and ligase,0.5881,30,0.9999995484354304,2407.9989126325163,114.0,0.9999998214707404,2407.9995701015428,113.0,nonessential
62,HNEAP_RS00325,WP_012822969.1,502585175.0,73294,74238,944.0,+,acyl-CoA synthetase,0.5831,15,0.963003295327953,2318.911935149711,48.0,0.9664026604708236,2327.097606413743,47.0,nonessential
63,HNEAP_RS00330,WP_012822970.1,502585176.0,74238,74837,599.0,+,outer membrane lipoprotein carrier protein LolA,0.5767,9,0.9999894503513542,2407.974596446061,46.0,0.99997778481039,2407.946505823419,44.0,nonessential
64,HNEAP_RS00335,WP_012822971.1,502585177.0,74834,77248,2414.0,+,MMPL domain-containing protein,0.5925,39,0.9952058832088277,2396.4557667668573,121.0,0.9921896451017566,2389.19266540503,116.0,nonessential
65,HNEAP_RS00340,WP_012822972.1,502585178.0,77245,77697,452.0,+,hypothetical protein,0.6004,5,0.9993009315213002,2406.316643103291,32.0,0.9995826914672766,2406.995121053202,32.0,nonessential
66,HNEAP_RS00345,WP_012822974.1,502585180.0,78057,79043,986.0,+,2-hydroxyacid dehydrogenase,0.5755,20,0.9744663958331857,2346.515081166311,51.0,0.9843844846160512,2370.3978389554513,51.0,nonessential
67,HNEAP_RS00350,WP_012822975.1,502585181.0,79194,79484,290.0,+,PilZ domain-containing protein,0.6254,2,0.9573297725595713,2305.250092323448,17.0,0.981909078295393,2364.4370605353065,18.0,nonessential
68,HNEAP_RS00355,WP_012822976.1,502585182.0,79586,80446,860.0,-,glutamate racemase,0.5877,17,0.7806527364073809,1879.8117892689731,38.0,0.8312968162746901,2001.7627335894538,38.0,nonessential
69,HNEAP_RS00360,WP_012822977.1,502585183.0,80598,80861,263.0,-,Txe/YoeB family addiction module toxin,0.4848,7,0.17787763460762213,428.3293441351541,7.0,0.20392754126508178,491.0575193663169,7.0,nonessential
70,HNEAP_RS00365,WP_012822978.1,502585184.0,80858,81100,242.0,-,prevent-host-death family protein,0.4691,7,0.15177425499807334,365.4724060353606,6.0,0.17420971045019795,419.4969827640767,6.0,nonessential
71,HNEAP_RS00370,WP_041600304.1,753844687.0,81093,81296,203.0,+,hypothetical protein,0.4755,11,0.9925160391497837,2389.9786222726793,15.0,0.9943362298133998,2394.3616413906666,15.0,nonessential
72,HNEAP_RS00375,WP_012822979.1,502585186.0,81463,81732,269.0,-,hypothetical protein,0.5296,4,0.15999440653029162,385.26653092494223,7.0,0.10467526240971751,252.05803188259978,6.0,nonessential
73,HNEAP_RS00380,WP_012822981.1,502585188.0,82067,82297,230.0,-,hypothetical protein,0.5022,6,0.9890334211633658,2381.592478161385,16.0,0.9917099168504269,2388.0374797758277,16.0,nonessential
74,HNEAP_RS00385,WP_041600305.1,753844688.0,82401,82835,434.0,-,hypothetical protein,0.4483,17,0.9843693033435497,2370.3612824512675,26.0,0.9684077522627816,2331.9258674487783,24.0,nonessential
75,HNEAP_RS00390,WP_012822983.1,502585190.0,82918,83169,251.0,-,hypothetical protein,0.4841,11,0.3326149101348987,800.936703604836,8.0,0.3681685410038038,886.5498467371596,8.0,nonessential
76,HNEAP_RS00395,WP_041600306.1,753844689.0,83469,83678,209.0,-,hypothetical protein,0.5571,3,0.16026734250727015,385.9237607575065,5.0,0.18174147172690586,437.6334639183893,5.0,nonessential
77,HNEAP_RS00400,WP_012822986.1,502585193.0,83787,83966,179.0,+,hypothetical protein,0.5833,1,0.5828867856408165,1403.5913798230863,7.0,0.6153431204402358,1481.7462340200877,7.0,nonessential
78,HNEAP_RS00405,WP_012822987.1,502585194.0,84404,84736,332.0,-,hypothetical protein,0.3664,16,0.008569966664109521,20.636479727175725,5.0,0.011202755178093977,26.976234468850297,5.0,nonessential
79,HNEAP_RS00410,WP_012822988.1,502585195.0,84810,85118,308.0,-,hypothetical protein,0.5372,10,0.43343720101339905,1043.716780040265,11.0,0.3585217057655346,863.3202674834073,10.0,nonessential
80,HNEAP_RS00415,WP_012822990.1,502585197.0,85475,86020,545.0,-,yfeABCD locus regulator,0.4505,16,0.669344579005153,1611.7817462444084,23.0,0.7205689914718383,1735.1301314641867,23.0,nonessential
81,HNEAP_RS00420,WP_012822991.1,502585198.0,86050,86634,584.0,-,ATPase,0.5504,16,0.9349248443935692,2251.2990252997147,30.0,0.9525438858008904,2293.725677008544,30.0,nonessential
82,HNEAP_RS00425,WP_012822993.1,502585200.0,87553,87843,290.0,-,DUF1330 domain-containing protein,0.3746,13,0.0001030303302763804,0.24809703530552402,1.0,1.1373860104542275e-05,0.027388255131737798,0.0,ambiguous
83,HNEAP_RS00430,WP_041600487.1,753844870.0,87840,88211,371.0,-,VOC family protein,0.4194,16,2.9846385027129754e-07,0.0007187009514532845,0.0,4.7312054556039764e-07,0.0011392742737094375,0.0,essential
84,HNEAP_RS00435,WP_012822995.1,502585202.0,88585,89196,611.0,-,cation transporter,0.4804,34,0.7552406368023853,1818.6194534201438,27.0,0.7409341396917469,1784.1694083777265,26.0,nonessential
85,HNEAP_RS00440,WP_041600307.1,753844690.0,89303,89782,479.0,-,N-acetyltransferase,0.5375,14,7.823296108960763e-08,0.00018838497030377517,1.0,1.3759131338064925e-07,0.0003313198826206034,1.0,essential
86,HNEAP_RS00445,WP_012822997.1,502585204.0,90138,90461,323.0,-,hypothetical protein,0.4722,12,0.9651039021698768,2323.9701964250635,19.0,0.9229276185351314,2222.409705432596,17.0,nonessential
87,HNEAP_RS12420,WP_012822998.1,502585205.0,90867,91082,215.0,-,hypothetical protein,0.4444,5,0.7630470200471857,1837.417224273623,10.0,0.7911450589732266,1905.0773020075296,10.0,nonessential
88,HNEAP_RS00450,WP_012822999.1,502585206.0,91085,91495,410.0,-,mercury transporter MerC,0.4696,17,0.2477972794794962,596.6958489866269,13.0,0.287886471427251,693.2306231968204,13.0,nonessential
89,HNEAP_RS00455,WP_012823000.1,502585207.0,91540,91896,356.0,-,hypothetical protein,0.5042,10,0.3416901840198305,822.7899631197517,12.0,0.28099958363009453,676.6469973812676,11.0,nonessential
90,HNEAP_RS00460,WP_012823001.1,502585208.0,91913,92266,353.0,-,hypothetical protein,0.5395,11,0.985074633382873,2372.059717185958,22.0,0.9657810526364793,2325.600774748642,20.0,nonessential
91,HNEAP_RS00465,WP_012823002.1,502585209.0,92363,93529,1166.0,-,hypothetical protein,0.4053,49,0.5814800809086098,1400.2040348279324,47.0,0.6055302949974755,1458.1169503539209,46.0,nonessential
92,HNEAP_RS00470,WP_041600489.1,753844872.0,93675,93935,260.0,+,integrase,0.5134,8,0.999206992235946,2406.090437304158,21.0,0.9971342136649366,2401.0991865051674,19.0,nonessential
93,HNEAP_RS00480,WP_012823003.1,502585210.0,94568,95170,602.0,+,class I SAM-dependent methyltransferase,0.5688,7,0.9588049385868774,2308.802292117201,32.0,0.9814934077978813,2363.436125977298,33.0,nonessential
94,HNEAP_RS00485,WP_012823004.1,502585211.0,95561,98821,3260.0,-,SNF2-like protein,0.5747,55,0.9999999999999999,2407.9999999999995,260.0,0.9999999999999999,2407.9999999999995,252.0,nonessential
95,HNEAP_RS00490,WP_012823005.1,502585212.0,99273,99587,314.0,+,ferrous iron transport protein A,0.5937,5,0.12200900121445168,293.79767492439964,8.0,0.0816015542570382,196.496542650948,7.0,nonessential
96,HNEAP_RS00495,WP_012823006.1,502585213.0,99584,99838,254.0,+,ferrous iron transport protein A,0.5725,3,0.0022631315471143467,5.449620765451347,2.0,0.0029291154360035735,7.053309969896605,2.0,nonessential
97,HNEAP_RS00500,WP_012823007.1,502585214.0,99908,102244,2336.0,+,Fe(2+) transporter permease subunit FeoB,0.5627,41,1.2697730515568852e-36,3.0576135081489794e-33,3.0,2.1017438205109138e-35,5.060999119790281e-32,3.0,essential
98,HNEAP_RS12055,WP_012823008.1,502585215.0,102268,102612,344.0,+,hypothetical protein,0.5884,6,0.9406591610995321,2265.107259927673,19.0,0.8217239021576471,1978.7111563956144,16.0,nonessential
99,HNEAP_RS00510,WP_012823009.1,502585216.0,102736,103629,893.0,-,molecular chaperone DnaJ,0.5884,11,0.8848803340069067,2130.791844288631,42.0,0.8152320562729654,1963.0787915053006,39.0,nonessential
100,HNEAP_RS00515,WP_012823010.1,502585217.0,103831,103956,125.0,-,50S ribosomal protein L36,0.4683,3,0.44390311162655405,1068.918692796742,4.0,0.4711935061993171,1134.6339629279555,4.0,nonessential
101,HNEAP_RS00525,WP_012823011.1,502585218.0,104375,104971,596.0,+,imidazoleglycerol-phosphate dehydratase,0.5695,11,3.293182785868707e-11,7.929984148371847e-08,0.0,6.903006277537521e-11,1.662243911631035e-07,0.0,essential
102,HNEAP_RS00530,WP_012823012.1,502585219.0,104974,105624,650.0,+,imidazole glycerol phosphate synthase subunit HisH,0.5822,14,3.697171703262828e-12,8.90278946145689e-09,0.0,8.287322101887595e-12,1.995587162134533e-08,0.0,essential
103,HNEAP_RS00535,WP_012823013.1,502585220.0,105661,106416,755.0,+,1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase,0.5913,12,5.261879119061181e-14,1.2670604918699323e-10,0.0,1.343729650454468e-13,3.235700998294359e-10,0.0,essential
104,HNEAP_RS00540,WP_012823014.1,502585221.0,106496,107269,773.0,+,imidazole glycerol phosphate synthase subunit HisF,0.615,7,8.363289503297002e-13,2.013880112393918e-09,1.0,2.1177959874051087e-12,5.099652737671502e-09,1.0,essential
105,HNEAP_RS00545,WP_012823015.1,502585222.0,107266,107676,410.0,+,phosphoribosyl-AMP cyclohydrolase,0.5693,7,6.151257597423119e-08,0.00014812228294594872,0.0,1.0234736385815477e-07,0.0002464524521704367,0.0,essential
106,HNEAP_RS00550,WP_012823016.1,502585223.0,107663,108037,374.0,+,phosphoribosyl-ATP diphosphatase,0.5733,6,3.5840766346883923e-05,0.08630456536329649,2.0,6.717853384192799e-06,0.01617659094913626,1.0,ambiguous
107,HNEAP_RS00555,WP_012823017.1,502585225.0,108062,108343,281.0,+,twin-arginine translocase subunit TatA,0.5355,3,1.1423576581245333e-05,0.02750797240763876,0.0,1.619366772529103e-05,0.0389943518825008,0.0,essential
108,HNEAP_RS12060,WP_012823018.1,502585226.0,108390,109016,626.0,+,twin-arginine translocase subunit TatB,0.5598,6,1.1412008909096482e-06,0.002748011745310433,5.0,4.089352812406245e-07,0.0009847161572274239,4.0,essential
109,HNEAP_RS00565,WP_081441171.1,1174219990.0,109082,110113,1031.0,+,twin-arginine translocase subunit TatC,0.5601,23,1.1066710556861106e-13,2.6648639020921546e-10,4.0,2.9703869959275977e-12,7.152691886193656e-09,5.0,essential
110,HNEAP_RS00570,WP_012823020.1,502585228.0,110181,111722,1541.0,+,2 3-bisphosphoglycerate-independent phosphoglycerate mutase,0.5927,24,7.889637583657186e-28,1.8998247301446505e-24,0.0,5.347088865061906e-27,1.2875789987069069e-23,0.0,essential
111,HNEAP_RS00575,WP_012823021.1,502585229.0,111734,112534,800.0,-,iron export ABC transporter permease subunit FetB,0.5955,12,0.2842215911903855,684.4055915864483,28.0,0.2783837287175238,670.3480187517973,27.0,nonessential
112,HNEAP_RS00580,WP_012823022.1,502585230.0,112531,113148,617.0,-,ABC transporter,0.5437,10,0.20824773852441608,501.46055436679393,20.0,0.18841446487242056,453.7020314127887,19.0,nonessential
113,HNEAP_RS00585,WP_041600309.1,753844692.0,113272,114618,1346.0,-,hypothetical protein,0.5828,22,0.764204533878809,1840.2045175801723,58.0,0.7046843323394623,1696.8798722734252,55.0,nonessential
114,HNEAP_RS00590,WP_012823024.1,502585232.0,114766,116844,2078.0,+,DNA helicase RecG,0.6013,21,0.9999999999999999,2407.9999999999995,171.0,0.9999999999999999,2407.9999999999995,168.0,nonessential
115,HNEAP_RS00595,WP_012823025.1,502585233.0,117014,117433,419.0,+,Hsp20/alpha crystallin family protein,0.5571,5,0.9513448376382747,2290.8383690329656,23.0,0.9413598871585739,2266.794608277846,22.0,nonessential
116,HNEAP_RS12065,WP_012823026.1,502585234.0,117857,118837,980.0,+,AraC family transcriptional regulator,0.6483,14,0.9995184127151077,2406.840337817979,60.0,0.9996200218286914,2407.085012563489,59.0,nonessential
117,HNEAP_RS00605,WP_081441065.1,1174219884.0,118927,120123,1196.0,+,OmpA family protein,0.6708,10,0.9999801197193813,2407.95212828427,77.0,0.9998922326437633,2407.740496206182,72.0,nonessential
118,HNEAP_RS00610,WP_012823028.1,502585236.0,120120,121379,1259.0,+,hypothetical protein,0.7175,6,0.9999957039848516,2407.9896551955226,83.0,0.9999863326319113,2407.9670889776426,79.0,nonessential
119,HNEAP_RS00615,WP_012823029.1,502585237.0,121407,121916,509.0,+,hypothetical protein,0.5529,9,0.8362561903542918,2013.7049063731347,24.0,0.8180030415198308,1969.7513239797527,23.0,nonessential
120,HNEAP_RS00620,WP_012823030.1,502585238.0,121913,122284,371.0,+,hypothetical protein,0.6075,6,0.9580146546689022,2306.8992884427166,21.0,0.9155574872202125,2204.662429226272,19.0,nonessential
121,HNEAP_RS12070,WP_012823031.1,502585239.0,122315,123301,986.0,+,AraC family transcriptional regulator,0.5633,20,0.9999998849719653,2407.9997230124927,74.0,0.9999999269881624,2407.999824187495,73.0,nonessential
122,HNEAP_RS12075,WP_012823032.1,502585240.0,123488,126406,2918.0,+,outer membrane autotransporter barrel domain-containing protein,0.5725,68,0.9999999998934647,2407.999999743463,188.0,0.9999999999969409,2407.9999999926335,190.0,nonessential
123,HNEAP_RS00635,WP_012823033.1,502585241.0,126577,127962,1385.0,-,diguanylate cyclase,0.6075,17,0.9998117817114809,2407.5467703612458,82.0,0.999539656350361,2406.8914924916694,78.0,nonessential
124,HNEAP_RS00640,WP_012823034.1,502585242.0,127966,128337,371.0,-,response regulator,0.5806,2,0.9989677538529139,2405.514351277817,27.0,0.997222579242792,2401.311970816643,25.0,nonessential
125,HNEAP_RS00645,WP_012823035.1,502585243.0,128341,130917,2576.0,-,sensor histidine kinase,0.5813,35,0.9996646677744738,2407.1925200009327,137.0,0.9992479955746824,2406.189173343835,131.0,nonessential
126,HNEAP_RS00650,WP_081441066.1,1174219885.0,131115,131918,803.0,+,serine/threonine-protein phosphatase,0.5908,11,0.9999526431764618,2407.88596476892,55.0,0.9999600453240075,2407.90378914021,54.0,nonessential
127,HNEAP_RS00655,WP_012823037.1,502585245.0,131937,133043,1106.0,+,magnesium and cobalt transport protein CorA,0.5402,25,0.9999756682915459,2407.9414092460424,72.0,0.9999711463346048,2407.9305203737285,70.0,nonessential
128,HNEAP_RS00660,WP_081441067.1,1174219886.0,133150,134403,1253.0,+,glycosyltransferase family 1 protein,0.5789,28,0.9999999999999981,2407.9999999999955,112.0,0.999999999999991,2407.999999999978,108.0,nonessential
129,HNEAP_RS00665,WP_081441068.1,1174219887.0,134342,134968,626.0,+,phosphatase PAP2 family protein,0.5694,11,0.9999999758588373,2407.99994186808,55.0,0.9999997073094558,2407.9992952011694,51.0,nonessential
130,HNEAP_RS00670,WP_012823040.1,502585248.0,135220,136077,857.0,+,general secretion pathway protein GspC,0.5967,12,0.9999966734863133,2407.991989755042,62.0,0.9999974581096946,2407.9938791281447,61.0,nonessential
131,HNEAP_RS00675,WP_012823041.1,502585249.0,136074,138251,2177.0,+,type II secretion system protein GspD,0.5822,38,0.999999266713154,2407.998234245275,133.0,0.9999989375546992,2407.9974416317154,129.0,nonessential
132,HNEAP_RS00680,WP_012823042.1,502585250.0,138262,139770,1508.0,+,type II secretion system protein GspE,0.611,20,0.9999999995498151,2407.9999989159546,111.0,0.999999999672731,2407.9999992119365,109.0,nonessential
133,HNEAP_RS00685,WP_012823043.1,502585251.0,139777,141000,1223.0,+,type II secretion system protein GspF,0.5915,18,0.6743097015373525,1623.7377613019448,51.0,0.7921516914053766,1907.5012729041468,52.0,nonessential
134,HNEAP_RS00690,WP_012823044.1,502585252.0,141003,141503,500.0,+,type II secretion system protein GspG,0.5669,10,0.010551604870986915,25.408264529336492,10.0,0.014637445076833362,35.246967745014736,10.0,nonessential
135,HNEAP_RS12080,WP_012823045.1,502585253.0,141512,142153,641.0,+,prepilin-type cleavage/methylation domain-containing protein,0.5685,16,0.8470130304835998,2039.6073774045083,30.0,0.8820046138559371,2123.8671101650966,30.0,nonessential
136,HNEAP_RS12085,WP_012823046.1,502585254.0,142153,142545,392.0,+,type II secretion system protein GspI,0.5878,10,0.9999775129547962,2407.9458511951493,33.0,0.9999312042828223,2407.8343399130363,31.0,nonessential
137,HNEAP_RS00705,WP_012823047.1,502585255.0,142542,143303,761.0,+,type II secretion system protein GspJ,0.5945,6,0.14365866184208045,345.93005771572973,24.0,0.06568103872466759,158.15994124899956,21.0,nonessential
138,HNEAP_RS00710,WP_012823048.1,502585256.0,143300,144247,947.0,+,general secretion pathway protein GspK,0.5897,20,0.9034315199761987,2175.4631001026864,45.0,0.9509652154769475,2289.9242388684893,46.0,nonessential
139,HNEAP_RS00715,WP_012823049.1,502585257.0,144220,145470,1250.0,+,type II secretory pathway component PulL-like protein,0.5947,16,0.9999999986010706,2407.999996631378,95.0,0.9999999889791679,2407.9999734618364,90.0,nonessential
140,HNEAP_RS00720,WP_012823050.1,502585258.0,145507,146025,518.0,+,type II secretion system protein M,0.5896,5,0.9966285831286307,2399.8816281737427,33.0,0.9933003835960298,2391.86732369924,31.0,nonessential
141,HNEAP_RS00725,WP_012823051.1,502585259.0,146022,146858,836.0,+,type II secretion system protein N,0.5866,17,0.999988585260254,2407.972513306692,59.0,0.9999379619403188,2407.8506123522875,55.0,nonessential
142,HNEAP_RS00730,WP_012823052.1,502585260.0,147180,147905,725.0,+,DUF4395 domain-containing protein,0.5441,18,0.8173731589015332,1968.234566634892,33.0,0.8590634413935034,2068.6247668755564,33.0,nonessential
143,HNEAP_RS00735,WP_049772433.1,908628400.0,148001,149407,1406.0,-,hypothetical protein,0.5245,46,0.1960651253767247,472.1248219071531,49.0,0.1799973848772469,433.4337027844105,47.0,nonessential
144,HNEAP_RS00740,WP_012823054.1,502585262.0,150296,152344,2048.0,+,BCCT family transporter,0.5476,39,0.9999999991056103,2407.9999978463097,139.0,0.9999999954407222,2407.999989021259,133.0,nonessential
145,HNEAP_RS00745,WP_012823055.1,502585263.0,152452,153762,1310.0,+,MFS transporter,0.5873,26,0.36939003062683806,889.4911937494261,49.0,0.51290528676701,1235.07593053496,50.0,nonessential
146,HNEAP_RS00750,WP_012823056.1,502585264.0,153774,155000,1226.0,-,MFS transporter,0.577,15,0.44137790225741846,1062.8379886358637,47.0,0.4090160941966624,984.9107548255631,45.0,nonessential
147,HNEAP_RS12090,WP_012823057.1,502585265.0,155248,156309,1061.0,+,peptidoglycan-binding lysin domain-containing protein-containing protein,0.548,17,0.9267174367625988,2231.535587724338,51.0,0.9134003655570144,2199.4680802612907,49.0,nonessential
148,HNEAP_RS00760,WP_012823058.1,502585266.0,156405,158078,1673.0,-,serine/threonine protein kinase,0.5639,35,0.9999990096720318,2407.9976152902527,107.0,0.9999992606431465,2407.998219628697,105.0,nonessential
149,HNEAP_RS00765,WP_012823059.1,502585267.0,158292,158810,518.0,-,phosphopeptide-binding protein,0.5318,14,0.9831897730248382,2367.5209734438104,30.0,0.988553217002096,2380.436146541047,30.0,nonessential
150,HNEAP_RS00770,WP_012823060.1,502585268.0,159004,159393,389.0,-,NADPH-dependent 7-cyano-7-deazaguanine reductase QueF,0.5436,6,0.7135144744560664,1718.142854490208,17.0,0.6685137542915172,1609.7811203339734,16.0,nonessential
151,HNEAP_RS00775,WP_081441069.1,1174219888.0,159510,163034,3524.0,+,chromosome segregation protein SMC,0.6057,34,0.9999999999999999,2407.9999999999995,246.0,0.9999999999999999,2407.9999999999995,240.0,nonessential
152,HNEAP_RS00780,WP_012823062.1,502585270.0,163039,164034,995.0,+,cell division protein ZipA,0.5703,11,3.9348350720241143e-14,9.475082853434067e-11,3.0,1.2336370531648716e-13,2.9705980240210106e-10,3.0,essential
153,HNEAP_RS00785,WP_012823063.1,502585271.0,164040,166097,2057.0,+,NAD-dependent DNA ligase LigA,0.5982,33,1.5096557927804854e-30,3.6352511490154086e-27,4.0,1.712797798441671e-29,4.124417098647544e-26,4.0,essential
154,HNEAP_RS00790,WP_041600514.1,753844897.0,166155,167123,968.0,+,octaprenyl diphosphate synthase,0.6109,15,9.438862963834639e-18,2.2728782016913812e-14,0.0,3.140230177204023e-17,7.561674266707288e-14,0.0,essential
155,HNEAP_RS00800,WP_012823065.1,502585273.0,167318,167785,467.0,-,Lrp/AsnC family transcriptional regulator,0.5513,10,0.9783727691315584,2355.9216280687924,27.0,0.9746298009068619,2346.9085605837236,26.0,nonessential
156,HNEAP_RS00810,WP_012823066.1,502585274.0,169850,171724,1874.0,+,ABC transporter ATP-binding protein,0.5888,24,0.8593087341024706,2069.215431718749,83.0,0.9114453967169369,2194.7605152943843,83.0,nonessential
157,HNEAP_RS00815,WP_081441070.1,1174219889.0,171795,172319,524.0,+,phosphohistidine phosphatase SixA,0.5752,4,0.7345734491442699,1768.852865539402,23.0,0.7797150019517475,1877.5537246998078,23.0,nonessential
158,HNEAP_RS00820,WP_012823068.1,502585276.0,172415,172978,563.0,+,rhombosortase,0.555,13,0.6104089158327854,1469.8646693253474,23.0,0.5846313332222752,1407.7922503992388,22.0,nonessential
159,HNEAP_RS00825,WP_012823069.1,502585277.0,173038,174135,1097.0,+,transaldolase,0.5638,23,0.9814137546843036,2363.244321279803,57.0,0.9779277621636832,2354.850051290149,55.0,nonessential
160,HNEAP_RS00830,WP_012823070.1,502585278.0,174196,174966,770.0,-,hypothetical protein,0.537,10,0.9982830581658225,2403.8656040633005,47.0,0.9990677356336412,2405.755107405808,47.0,nonessential
161,HNEAP_RS00835,WP_041600516.1,753844899.0,174963,175508,545.0,-,RNA polymerase sigma factor,0.5421,8,0.9879842864571318,2379.066161788773,32.0,0.9920553439993293,2388.869268350385,32.0,nonessential
162,HNEAP_RS00840,WP_012823072.1,502585280.0,175789,176268,479.0,+,hypothetical protein,0.55,6,0.9999979506725474,2407.995065219494,41.0,0.9999990422382911,2407.997693709805,41.0,nonessential
163,HNEAP_RS00845,WP_012823073.1,502585281.0,176452,177756,1304.0,+,phosphate porin,0.5464,38,0.9999997230087507,2407.9993330050715,90.0,0.9999999250009302,2407.9998194022396,90.0,nonessential
164,HNEAP_RS00850,WP_012823074.1,502585282.0,177803,178861,1058.0,-,sensor domain-containing diguanylate cyclase,0.576,17,0.9999022133009922,2407.764529628789,67.0,0.9996568960544546,2407.1738056991267,63.0,nonessential
165,HNEAP_RS00855,WP_012823075.1,502585283.0,178858,179517,659.0,-,protein disulfide oxidoreductase,0.5864,9,0.9999718979211678,2407.932330194172,48.0,0.9999869550601067,2407.968587784737,48.0,nonessential
166,HNEAP_RS00860,WP_012823076.1,502585284.0,179601,180782,1181.0,+,bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC,0.5854,16,1.693161930066249e-21,4.077133927599528e-18,0.0,7.33856364819193e-21,1.7671261264846168e-17,0.0,essential
167,HNEAP_RS00865,WP_012823077.1,502585285.0,180787,181272,485.0,+,dUTP diphosphatase,0.6111,11,0.26829698277545516,646.059134523296,16.0,0.31389005768331335,755.8472589014185,16.0,nonessential
168,HNEAP_RS00870,WP_012823078.1,502585286.0,181310,182197,887.0,+,acetylglutamate kinase,0.5631,12,1.778612275746413e-13,4.2828983599973624e-10,2.0,5.030497527793401e-13,1.2113438046926509e-09,2.0,essential
169,HNEAP_RS00875,WP_049772550.1,908628517.0,182540,182836,296.0,+,hypothetical protein,0.5589,5,0.16688083639083398,401.84905402912824,8.0,0.1935475616048787,466.06252834454796,8.0,nonessential
170,HNEAP_RS00880,WP_081441071.1,1174219890.0,182847,183539,692.0,-,DUF4124 domain-containing protein,0.5036,10,0.7874601735615762,1896.2040979362755,31.0,0.8324843121082821,2004.6222235567434,31.0,nonessential
171,HNEAP_RS00885,WP_012823081.1,502585290.0,183708,184925,1217.0,-,MFS transporter,0.5739,18,0.9999999999207406,2407.9999998091434,97.0,0.9999999992734979,2407.999998250583,92.0,nonessential
172,HNEAP_RS00890,WP_012823082.1,502585291.0,185244,185927,683.0,+,ArsR family transcriptional regulator,0.595,13,0.9453486658458858,2276.399587356893,35.0,0.9744098080503085,2346.378817785143,36.0,nonessential
173,HNEAP_RS00895,WP_012823083.1,502585292.0,185924,186892,968.0,+,ATPase AAA,0.6047,14,0.8008291730000497,1928.3966485841197,43.0,0.7644676048732393,1840.8379925347601,41.0,nonessential
174,HNEAP_RS00900,WP_012823084.1,502585293.0,187055,188128,1073.0,+,DUF58 domain-containing protein,0.6108,11,0.5042477692657132,1214.2286283918374,42.0,0.5220527187504242,1257.1029467510216,41.0,nonessential
175,HNEAP_RS00905,WP_041600313.1,753844696.0,188125,188670,545.0,+,hypothetical protein,0.5971,6,0.8567546129932029,2063.0651080876323,26.0,0.8878631975917046,2137.974579800825,26.0,nonessential
176,HNEAP_RS00910,WP_012823086.1,502585295.0,188678,189697,1019.0,+,VWA domain-containing protein,0.6049,17,0.9995309617108942,2406.8705557998333,62.0,0.99992750415275,2407.825429999822,64.0,nonessential
177,HNEAP_RS00915,WP_012823087.1,502585296.0,189700,191658,1958.0,+,hypothetical protein,0.5865,36,0.953617459564236,2296.3108426306803,92.0,0.9751337093830997,2348.121972194504,92.0,nonessential
178,HNEAP_RS00920,WP_041600314.1,753844697.0,191745,193094,1349.0,+,hypothetical protein,0.5689,29,0.9708953471471914,2337.915995930437,67.0,0.9834124015251492,2368.057062872559,67.0,nonessential
179,HNEAP_RS00925,WP_081441072.1,1174219891.0,193091,193804,713.0,-,hypothetical protein,0.5098,22,0.9949089790633204,2395.7408215844757,42.0,0.9969888084678151,2400.749050790499,42.0,nonessential
180,HNEAP_RS00930,WP_012823090.1,502585299.0,194015,194362,347.0,-,High potential iron-sulfur protein,0.5603,8,0.8475079225613532,2040.7990775277385,17.0,0.8740862568313588,2104.799706449912,17.0,nonessential
181,HNEAP_RS00935,WP_012823091.1,502585300.0,194496,195998,1502.0,+,SELO family protein,0.5928,34,0.9999999996405804,2407.9999991345176,111.0,0.9999999999358705,2407.9999998455764,111.0,nonessential
182,HNEAP_RS00940,WP_012823092.1,502585301.0,196011,197153,1142.0,-,hypothetical protein,0.5713,24,0.5795265543665484,1395.4999429146487,46.0,0.6592387400350621,1587.4468860044296,46.0,nonessential
183,HNEAP_RS00945,WP_012823093.1,502585302.0,197336,197824,488.0,+,diaminobutyrate acetyltransferase,0.5583,12,0.9993236456877608,2406.371338816128,34.0,0.999216280248175,2406.112802837605,33.0,nonessential
184,HNEAP_RS00950,WP_012823094.1,502585303.0,197858,199147,1289.0,+,diaminobutyrate--2-oxoglutarate transaminase,0.5465,25,0.9987304121398405,2404.942832432736,73.0,0.9991163489731338,2405.872168327306,72.0,nonessential
185,HNEAP_RS00955,WP_012823095.1,502585304.0,199144,199551,407.0,+,ectoine synthase,0.5441,7,0.018447681818708737,44.42201781945064,8.0,0.047763242007546426,115.01388675417179,9.0,nonessential
186,HNEAP_RS00960,WP_012823096.1,502585305.0,199779,200633,854.0,-,inositol monophosphatase,0.5988,7,0.7930613897182329,1909.6918264415049,38.0,0.8417226613292883,2026.8681684809262,38.0,nonessential
187,HNEAP_RS00965,WP_012823097.1,502585306.0,200739,201752,1013.0,-,rhodanese,0.5621,18,0.9999999979949329,2407.999995171798,81.0,0.9999999997741065,2407.9999994560485,82.0,nonessential
188,HNEAP_RS00970,WP_081441073.1,1174219892.0,202045,202833,788.0,-,DUF2076 domain-containing protein,0.6008,12,0.99564525126415,2397.5137650440734,46.0,0.9959421458489425,2398.2286872042537,45.0,nonessential
189,HNEAP_RS00975,WP_012823099.1,502585308.0,202943,203884,941.0,-,bifunctional riboflavin kinase/FAD synthetase,0.604,9,1.5685245794117706e-10,3.7770071872235437e-07,6.0,6.5147322718773e-11,1.5687475310680539e-07,5.0,essential
190,HNEAP_RS00980,WP_012823100.1,502585309.0,204104,204946,842.0,+,type II restriction endonuclease,0.3689,62,1.4656494923780437e-06,0.003529283977646329,10.0,8.852243608988415e-07,0.0021316202610444103,9.0,essential
191,HNEAP_RS00985,WP_012823101.1,502585310.0,204946,205860,914.0,+,DNA adenine methylase,0.3858,52,7.901926912683676e-12,1.9027840005742293e-08,4.0,2.172864416583593e-11,5.2322575151332916e-08,4.0,essential
192,HNEAP_RS00990,WP_012823102.1,502585311.0,206010,206315,305.0,-,DUF3240 domain-containing protein,0.5686,6,0.4470978827921368,1076.6117017634654,11.0,0.48980945746899063,1179.4611735853293,11.0,nonessential
193,HNEAP_RS00995,WP_012823103.1,502585312.0,206312,209416,3104.0,-,CusA/CzcA family heavy metal efflux RND transporter,0.5923,37,0.9927099941199538,2390.4456658408485,150.0,0.9909340474652644,2386.1691862963567,145.0,nonessential
194,HNEAP_RS01000,WP_012823104.1,502585313.0,209416,210552,1136.0,-,efflux RND transporter periplasmic adaptor subunit,0.6033,13,0.9999999999999962,2407.999999999991,104.0,0.999999999999947,2407.9999999998727,99.0,nonessential
195,HNEAP_RS01005,WP_081441074.1,1174219893.0,210549,211937,1388.0,-,TolC family protein,0.599,15,0.9999999998615504,2407.9999996666133,106.0,0.9999999981247333,2407.999995484358,100.0,nonessential
196,HNEAP_RS01010,WP_012823106.1,502585315.0,212094,212882,788.0,+,DNA-binding response regulator,0.5754,16,0.9990311522184246,2405.6670145419666,49.0,0.9994944519824536,2406.782640373748,49.0,nonessential
197,HNEAP_RS01015,WP_012823107.1,502585316.0,212879,214294,1415.0,+,two-component sensor histidine kinase,0.5664,30,0.9999999999999999,2407.9999999999995,145.0,0.9999999999999999,2407.9999999999995,143.0,nonessential
198,HNEAP_RS01020,WP_012823108.1,502585317.0,214686,216095,1409.0,+,glutamate--ammonia ligase,0.5504,30,9.799810629978494e-24,2.3597943996988212e-20,1.0,5.464248163217042e-23,1.3157909577026638e-19,1.0,essential
199,HNEAP_RS01025,WP_012823109.1,502585318.0,216269,216736,467.0,-,tryptophan-rich sensory protein,0.5278,11,0.41665544738694416,1003.3063173077616,17.0,0.4689699117133287,1129.2795474056954,17.0,nonessential
200,HNEAP_RS01030,WP_012823110.1,502585319.0,216936,219419,2483.0,-,DUF2309 domain-containing protein,0.5841,39,0.9999999998574943,2407.9999996568463,165.0,0.9999999998442094,2407.999999624856,161.0,nonessential
201,HNEAP_RS01035,WP_012823111.1,502585320.0,219465,221120,1655.0,-,NADH dehydrogenase subunit 5,0.5634,26,0.9996981068836367,2407.273041375797,94.0,0.9998311797710653,2407.593480888725,93.0,nonessential
202,HNEAP_RS01040,WP_012823112.1,502585321.0,221411,222358,947.0,+,LysR family transcriptional regulator,0.5222,23,0.010901881736409054,26.251731221273,24.0,0.017202398728656792,41.423376138605555,24.0,nonessential
203,HNEAP_RS01045,WP_012823113.1,502585322.0,222448,222801,353.0,+,DUF3817 domain-containing protein,0.5282,6,0.5693633309394208,1371.0269009021254,14.0,0.7120342086704357,1714.5783744784092,15.0,nonessential
204,HNEAP_RS01050,WP_012823114.1,502585323.0,223050,223448,398.0,+,aminoacyl-tRNA hydrolase,0.5514,5,0.0013678287364411413,3.293731597350268,5.0,0.001935426792753823,4.660507716951206,5.0,nonessential
205,HNEAP_RS01055,WP_012823115.1,502585324.0,223467,224009,542.0,+,hypothetical protein,0.5617,11,0.6789400963106712,1634.8877519160962,23.0,0.7293658521861233,1756.3129720641848,23.0,nonessential
206,HNEAP_RS01060,WP_012823116.1,502585325.0,224238,225791,1553.0,+,thioredoxin domain-containing protein,0.536,42,0.9999999847194204,2407.9999632043646,108.0,0.9999997648325969,2407.9994337168932,101.0,nonessential
207,HNEAP_RS01065,WP_012823117.1,502585326.0,226041,227918,1877.0,+,DUF839 domain-containing protein,0.5501,43,0.9999988164360168,2407.9971499779285,117.0,0.9999992191094557,2407.998119615569,115.0,nonessential
208,HNEAP_RS01070,WP_012823118.1,502585327.0,228104,229846,1742.0,+,hypothetical protein,0.5559,40,0.9989727398571797,2405.5263575760887,95.0,0.9991306937166433,2405.906710469677,93.0,nonessential
209,HNEAP_RS12425,WP_012823119.1,502585328.0,229934,232051,2117.0,+,PKD domain-containing protein,0.5378,61,0.998328185906458,2403.9742716627507,111.0,0.9993858211813476,2406.521057404685,111.0,nonessential
210,HNEAP_RS01080,WP_041600317.1,753844700.0,232259,233389,1130.0,-,hypothetical protein,0.5553,18,0.4274624202483918,1029.3295079581276,43.0,0.3868781992751025,931.6027038544468,41.0,nonessential
211,HNEAP_RS01085,WP_012823121.1,502585330.0,233428,233628,200.0,-,DUF2892 domain-containing protein,0.4925,7,0.3161657341870342,761.3270879223784,6.0,0.34710934310189284,835.8392981893579,6.0,nonessential
212,HNEAP_RS01090,WP_012823122.1,502585331.0,233704,234051,347.0,-,hypothetical protein,0.5575,8,0.9991994912110722,2406.072374836262,26.0,0.999490506407827,2406.773139430047,26.0,nonessential
213,HNEAP_RS01095,WP_012823123.1,502585332.0,234504,235751,1247.0,+,lipoprotein-releasing system transmembrane subunit LolC,0.5825,19,1.1692235769639836e-22,2.8154903733292724e-19,0.0,5.500521843060631e-22,1.324525659809e-18,0.0,essential
214,HNEAP_RS01100,WP_012823124.1,502585333.0,235744,236451,707.0,+,ABC transporter ATP-binding protein,0.6102,5,1.1108278675838614e-11,2.674873505141938e-08,1.0,2.5917813660207757e-11,6.241009529378028e-08,1.0,essential
215,HNEAP_RS01105,WP_012823125.1,502585334.0,236581,238059,1478.0,+,alkaline invertase,0.5903,19,0.9999999958230872,2407.999989941994,106.0,0.9999999983348594,2407.9999959903416,105.0,nonessential
216,HNEAP_RS01110,WP_012823126.1,502585335.0,238056,240410,2354.0,+,sucrose-phosphate synthase,0.5953,50,0.9999999999999999,2407.9999999999995,186.0,0.9999999999999999,2407.9999999999995,182.0,nonessential
217,HNEAP_RS01115,WP_012823127.1,502585336.0,240407,241288,881.0,+,haloacid dehalogenase,0.576,12,0.9999850518554944,2407.9640048680303,61.0,0.9999781169461718,2407.9473056063816,59.0,nonessential
218,HNEAP_RS01120,WP_012823128.1,502585337.0,241531,242199,668.0,+,Small-conductance mechanosensitive channel-like protein,0.574,12,0.9999999999760072,2407.9999999422253,65.0,0.9999999999991697,2407.9999999980005,67.0,nonessential
219,HNEAP_RS01125,WP_012823129.1,502585338.0,242272,242757,485.0,+,pilin,0.5658,12,0.9999934684937579,2407.984272132969,40.0,0.9999181584654748,2407.8029255848633,36.0,nonessential
220,HNEAP_RS01130,WP_081441172.1,1174219991.0,243322,244044,722.0,+,monofunctional biosynthetic peptidoglycan transglycosylase,0.5574,18,0.5751586283084149,1384.981976966663,29.0,0.489251148062844,1178.1167645353282,27.0,nonessential
221,HNEAP_RS01135,WP_012823131.1,502585340.0,244073,245356,1283.0,+,Vi polysaccharide biosynthesis UDP-N-acetylglucosamine C-6 dehydrogenase TviB,0.5911,32,0.9604151587768647,2312.6797023346903,63.0,0.9569369109877199,2304.30408165843,61.0,nonessential
222,HNEAP_RS01140,WP_012823132.1,502585341.0,245635,245952,317.0,+,nucleotidyltransferase domain-containing protein,0.5723,5,0.8686046231837297,2091.599932626421,16.0,0.8335524725515094,2007.1943539040346,15.0,nonessential
223,HNEAP_RS01145,WP_012823133.1,502585342.0,245949,246482,533.0,+,hypothetical protein,0.5618,15,0.7072090156981432,1702.959309801129,23.0,0.6821918564382434,1642.7179903032902,22.0,nonessential
224,HNEAP_RS12100,WP_081441075.1,1174219894.0,246436,247197,761.0,+,class I SAM-dependent methyltransferase,0.5735,20,0.9999999999999997,2407.999999999999,82.0,0.9999999999999998,2407.9999999999995,81.0,nonessential
225,HNEAP_RS01155,WP_012823135.1,502585344.0,247194,248333,1139.0,+,group 1 glycosyl transferase,0.5842,24,0.9995425775626086,2406.8985267707612,68.0,0.9996701752621157,2407.2057820311743,67.0,nonessential
226,HNEAP_RS12105,WP_012823136.1,502585346.0,248330,249076,746.0,+,type 11 methyltransferase,0.4485,33,0.5774160043630214,1390.4177385061555,30.0,0.5704517937390964,1373.6479193237442,29.0,nonessential
227,HNEAP_RS01165,WP_012823137.1,502585347.0,249073,249999,926.0,+,hypothetical protein,0.4509,31,0.9805889764500801,2361.258255291793,49.0,0.9639548118834024,2321.2031870152327,46.0,nonessential
228,HNEAP_RS12430,WP_012823138.1,502585348.0,249996,250550,554.0,+,acyltransferase,0.4216,26,0.013744258346894411,33.09617409932174,12.0,0.019211858110451396,46.26215432996696,12.0,nonessential
229,HNEAP_RS01170,WP_012823139.1,502585349.0,250516,251679,1163.0,-,DegT/DnrJ/EryC1/StrS family aminotransferase,0.5533,32,0.8641109212614934,2080.779098397676,53.0,0.8103915264831807,1951.422795771499,50.0,nonessential
230,HNEAP_RS01175,WP_041600537.1,753844920.0,251829,252146,317.0,-,hypothetical protein,0.4277,10,0.004453925400517209,10.725052364445439,4.0,0.001700407518416185,4.094581304346173,3.0,nonessential
231,HNEAP_RS01180,WP_012823141.1,502585351.0,252310,252606,296.0,-,nucleotidyltransferase domain-containing protein,0.4613,7,0.16688083639083398,401.84905402912824,8.0,0.1935475616048787,466.06252834454796,8.0,nonessential
232,HNEAP_RS01185,WP_012823143.1,502585353.0,252850,253179,329.0,-,type II toxin-antitoxin system RelE/ParE family toxin,0.5061,14,0.6712360876601458,1616.336499085631,14.0,0.711477088565595,1713.2368292659528,14.0,nonessential
233,HNEAP_RS01190,WP_012823144.1,502585354.0,253166,253417,251.0,-,type II toxin-antitoxin system prevent-host-death family antitoxin,0.5278,5,0.002500999938775926,6.022407852572431,2.0,0.003225174192121102,7.766219454627613,2.0,nonessential
234,HNEAP_RS01195,WP_012823145.1,502585355.0,253598,253858,260.0,-,Txe/YoeB family addiction module toxin,0.4291,16,0.5423975911203747,1306.0933994178622,10.0,0.45434989715047525,1094.0745523383443,9.0,nonessential
235,HNEAP_RS01200,WP_012823146.1,502585356.0,253855,254106,251.0,-,type II toxin-antitoxin system prevent-host-death family antitoxin,0.5357,3,0.3326149101348987,800.936703604836,8.0,0.3681685410038038,886.5498467371596,8.0,nonessential
236,HNEAP_RS01205,WP_012823147.1,502585357.0,254253,254816,563.0,-,Uma2 family endonuclease,0.5319,20,3.690517656905293e-08,8.886766517827946e-05,2.0,6.987504729377314e-08,0.00016825911388340572,2.0,essential
237,HNEAP_RS01210,WP_012823149.1,502585359.0,255234,256067,833.0,-,2 3 4 5-tetrahydropyridine-2 6-dicarboxylate N-succinyltransferase,0.5779,14,2.2350395948898673e-15,5.3819753444948e-12,0.0,6.288131374133034e-15,1.5141820348912346e-11,0.0,essential
238,HNEAP_RS01215,WP_012823150.1,502585360.0,256158,257315,1157.0,-,carbohydrate porin,0.5674,17,0.9995663585293894,2406.9557913387694,69.0,0.9987439699122259,2404.97547954864,65.0,nonessential
239,HNEAP_RS01220,WP_012823151.1,502585361.0,257371,258576,1205.0,-,succinyldiaminopimelate transaminase,0.6128,22,0.9999268369072453,2407.8238232726467,75.0,0.9999191799360139,2407.8053852859216,73.0,nonessential
240,HNEAP_RS01225,WP_041600319.1,753844702.0,258617,259018,401.0,+,glyoxalase,0.6095,5,0.5745703948957682,1383.5655109090098,16.0,0.6227818338847819,1499.658655994555,16.0,nonessential
241,HNEAP_RS12110,WP_081441076.1,1174219895.0,258946,259941,995.0,-,META domain-containing protein,0.5522,21,0.9998504763589011,2407.639947072234,63.0,0.9996691555864512,2407.2033266521744,60.0,nonessential
242,HNEAP_RS01235,WP_049772434.1,908628401.0,259763,260527,764.0,-,ParA family protein,0.5503,15,0.8724482487312734,2100.855382944906,36.0,0.90562128442186,2180.736052887839,36.0,nonessential
243,HNEAP_RS01240,WP_012823155.1,502585365.0,260589,262061,1472.0,-,nitrogen regulation protein NR(I),0.6083,11,0.9999999999993396,2407.9999999984097,118.0,0.9999999999997982,2407.999999999514,117.0,nonessential
244,HNEAP_RS01245,WP_081441077.1,1174219896.0,262058,263335,1277.0,-,hypothetical protein,0.5305,23,0.9977196326107791,2402.508875326756,71.0,0.996334616948862,2399.17375761286,68.0,nonessential
245,HNEAP_RS01250,WP_041600321.1,753844704.0,263446,264177,731.0,-,DUF4124 domain-containing protein,0.5355,10,0.07230266775796547,174.10482396118084,21.0,0.1375377852917286,331.1909869824825,22.0,nonessential
246,HNEAP_RS01255,WP_012823158.1,502585368.0,264454,265569,1115.0,-,5-(carboxyamino)imidazole ribonucleotide synthase,0.5654,16,1.1543860555150378e-18,2.779761621680211e-15,1.0,4.468593249675573e-18,1.0760372545218781e-14,1.0,essential
247,HNEAP_RS01260,WP_012823159.1,502585369.0,265585,266127,542.0,-,5-(carboxyamino)imidazole ribonucleotide mutase,0.6188,7,0.08788560202254156,211.62852967028007,15.0,0.16496593298362297,397.23796662456414,16.0,nonessential
248,HNEAP_RS01265,WP_081441078.1,1174219897.0,266124,266582,458.0,-,hypothetical protein,0.5403,17,0.081058616007568,195.18914734622373,12.0,0.03379863814683557,81.38712065758006,10.0,nonessential
249,HNEAP_RS01270,WP_012823161.1,502585371.0,266669,267649,980.0,-,C4-dicarboxylate ABC transporter,0.5199,28,0.9999999900286795,2407.99997598906,77.0,0.9999999939956404,2407.999985541502,76.0,nonessential
250,HNEAP_RS01275,WP_012823162.1,502585372.0,267796,268461,665.0,+,integral membrane protein,0.5165,12,0.9416919754056757,2267.594276776867,34.0,0.8388797929634485,2020.022541455984,30.0,nonessential
251,HNEAP_RS01280,WP_012823163.1,502585373.0,268701,269039,338.0,+,cytochrome c554,0.5369,7,0.9828533630557027,2366.710898238132,21.0,0.9771642716818981,2353.0115662100106,20.0,nonessential
252,HNEAP_RS01285,WP_081441079.1,1174219898.0,269152,270015,863.0,-,phosphate transport system regulatory protein PhoU,0.5359,16,0.001480216477158382,3.5643612769973836,18.0,0.0025108815079773893,6.046202671209554,18.0,nonessential
253,HNEAP_RS01290,WP_012823165.1,502585375.0,270053,272128,2075.0,+,polyphosphate kinase 1,0.54,42,1.8856131963983265e-28,4.54055657692717e-25,6.0,1.5374578040765403e-22,3.702198392216309e-19,11.0,essential
254,HNEAP_RS01295,WP_012823166.1,502585376.0,272175,273347,1172.0,-,glutamate 5-kinase,0.624,14,5.975627211009861e-15,1.4389310324111745e-11,5.0,2.291094585969135e-15,5.516955763013677e-12,4.0,essential
255,HNEAP_RS01300,WP_012823167.1,502585377.0,273354,274481,1127.0,-,Obg family GTPase CgtA,0.5922,18,1.7062479524542258e-17,4.1086450695097756e-14,2.0,9.983895585370254e-16,2.4041220569571573e-12,3.0,essential
256,HNEAP_RS01305,WP_012823168.1,502585378.0,274634,274891,257.0,-,50S ribosomal protein L27,0.5814,3,0.002047419855808414,4.930187012786662,2.0,0.0026596315989513594,6.404392890274873,2.0,nonessential
257,HNEAP_RS01310,WP_012823169.1,502585379.0,274945,275256,311.0,-,50S ribosomal protein L21,0.5545,5,3.389731589983961e-06,0.008162473668681378,0.0,4.987551792005968e-06,0.01201002471515037,0.0,essential
258,HNEAP_RS01315,WP_041600322.1,753844705.0,275500,275892,392.0,+,hypothetical protein,0.598,3,0.999999999999951,2407.999999999882,51.0,0.9999999999997826,2407.9999999994766,49.0,nonessential
259,HNEAP_RS01320,WP_012823171.1,502585381.0,276080,278050,1970.0,+,copper oxidase,0.5804,44,0.9999999999282856,2407.9999998273115,139.0,0.9999999995745036,2407.9999989754047,133.0,nonessential
260,HNEAP_RS01325,WP_012823172.1,502585382.0,278073,278897,824.0,+,copper resistance protein B,0.5745,25,0.9991207842763268,2405.8828485373947,51.0,0.9995500986370269,2406.9166375179607,51.0,nonessential
261,HNEAP_RS01330,WP_012823173.1,502585388.0,279022,279285,263.0,+,hypothetical protein,0.5379,4,0.17787763460762213,428.3293441351541,7.0,0.20392754126508178,491.0575193663169,7.0,nonessential
262,HNEAP_RS01335,WP_012823174.1,502585389.0,279331,281040,1709.0,+,bilirubin oxidase,0.5643,31,0.9999974407012668,2407.9938372086503,107.0,0.9999988713586334,2407.9972822315895,106.0,nonessential
263,HNEAP_RS01340,WP_081441080.1,1174219899.0,281191,282558,1367.0,+,TolC family protein,0.606,14,0.9999980444651277,2407.9952910720276,90.0,0.9999834151794936,2407.960063752221,84.0,nonessential
264,HNEAP_RS12115,WP_012823176.1,502585391.0,282555,284438,1883.0,+,efflux RND transporter periplasmic adaptor subunit,0.6146,26,0.35714786133835885,860.0120501027682,71.0,0.4601954855082145,1108.1507291037806,71.0,nonessential
265,HNEAP_RS01350,WP_012823177.1,502585392.0,284451,287723,3272.0,+,AcrB/AcrD/AcrF family protein,0.6001,49,0.9950431671084147,2396.0639463970624,159.0,0.9983813844177827,2404.1023736780207,159.0,nonessential
266,HNEAP_RS01355,WP_012823178.1,502585393.0,287821,288228,407.0,+,DUF4332 domain-containing protein,0.5809,3,0.5504647045574826,1325.5190085744182,16.0,0.6924436269814016,1667.404253771215,17.0,nonessential
267,HNEAP_RS01360,WP_012823179.1,502585394.0,288319,288597,278.0,-,type II toxin-antitoxin system RelE/ParE family toxin,0.5125,11,0.0731901215529981,176.24181269961943,6.0,0.08745478770970395,210.59112880496713,6.0,nonessential
268,HNEAP_RS01365,WP_012823180.1,502585395.0,288597,288824,227.0,-,hypothetical protein,0.5219,6,0.8060651822496382,1941.0049588571287,11.0,0.7393959546758468,1780.4654588594392,10.0,nonessential
269,HNEAP_RS01370,WP_012823181.1,502585396.0,288905,289603,698.0,-,sulfite exporter TauE/SafE family protein,0.588,19,0.000556674824068054,1.340472976355874,12.0,1.0282970254883351e-06,0.002476139237375911,6.0,ambiguous
270,HNEAP_RS01375,WP_012823182.1,502585397.0,289695,293879,4184.0,+,ATP-dependent RNA helicase HrpA,0.6038,55,0.9980052910192975,2403.1967407744683,203.0,0.9995026868085632,2406.8024698350205,203.0,nonessential
271,HNEAP_RS01380,WP_012823183.1,502585398.0,294221,295990,1769.0,+,hypothetical protein,0.5056,56,0.9999999645484974,2407.999914632782,118.0,0.9999999770307778,2407.999944690113,116.0,nonessential
272,HNEAP_RS01385,WP_012823184.1,502585399.0,296366,296713,347.0,+,DUF3024 domain-containing protein,0.4425,9,0.0057178869319689934,13.768671732181335,5.0,0.007609468380459429,18.323599860146306,5.0,nonessential
273,HNEAP_RS01390,WP_012823185.1,502585400.0,296954,297256,302.0,-,type II toxin-antitoxin system RelE/ParE family toxin,0.4587,10,0.34446489779960454,829.4714739014478,10.0,0.3841092655352794,924.9351114089528,10.0,nonessential
274,HNEAP_RS01395,WP_012823186.1,502585401.0,297256,297495,239.0,-,type II toxin-antitoxin system ParD family antitoxin,0.4667,7,0.9697894946212561,2335.2531030479845,15.0,0.9881651361437626,2379.5016478341804,16.0,nonessential
275,HNEAP_RS01400,WP_012823187.1,502585402.0,297650,298324,674.0,-,anti-sigma-K factor RskA,0.5659,8,0.9681762075664486,2331.3683078200083,36.0,0.967397270793902,2329.492628071716,35.0,nonessential
276,HNEAP_RS01405,WP_081441081.1,1174219900.0,298326,299120,794.0,-,hypothetical protein,0.5698,12,0.999999999937483,2407.999999849459,72.0,0.999999999376469,2407.9999984985375,68.0,nonessential
277,HNEAP_RS01415,WP_012823189.1,502585404.0,299368,299625,257.0,+,hypothetical protein,0.5,5,0.5575456431396169,1342.5699086801974,10.0,0.5966677848956784,1436.7760260287937,10.0,nonessential
278,HNEAP_RS01420,WP_012823190.1,502585405.0,299957,300805,848.0,+,DUF692 domain-containing protein,0.5607,18,0.3609987214100578,869.2849211554192,31.0,0.5007412221912882,1205.784863036622,32.0,nonessential
279,HNEAP_RS12120,WP_012823191.1,502585406.0,300802,301551,749.0,+,DUF2063 domain-containing protein,0.5333,15,0.9999042852730256,2407.7695189374454,51.0,0.9998407633123043,2407.6165580560287,49.0,nonessential
280,HNEAP_RS01430,WP_012823192.1,502585407.0,301556,304075,2519.0,+,thioredoxin domain-containing protein,0.5671,46,0.998627626782778,2404.6953252929297,130.0,0.9991271553227172,2405.898190017103,128.0,nonessential
281,HNEAP_RS01435,WP_012823193.1,502585408.0,304266,304814,548.0,-,fatty acid hydroxylase,0.5337,11,0.9999757942814966,2407.941712629844,42.0,0.9999742692576082,2407.9380403723208,41.0,nonessential
282,HNEAP_RS01440,WP_012823194.1,502585409.0,305082,305684,602.0,+,DUF4124 domain-containing protein,0.5589,18,0.397073210678011,956.1522913126505,22.0,0.3723326445686379,896.5770081212801,21.0,nonessential
283,HNEAP_RS01445,WP_012823195.1,502585410.0,305666,306682,1016.0,-,aminoglycoside phosphotransferase,0.5624,17,0.9995647174680318,2406.9518396630206,62.0,0.9990903316519644,2405.8095186179303,59.0,nonessential
284,HNEAP_RS01450,WP_012823196.1,502585411.0,306894,307613,719.0,+,Zn-dependent hydrolase,0.5569,15,0.9999826474711867,2407.9582151106174,52.0,0.9999923629614181,2407.9816100110947,52.0,nonessential
285,HNEAP_RS01455,WP_012823197.1,502585412.0,307610,308758,1148.0,+,pyridine nucleotide-disulfide oxidoreductase,0.584,21,0.9999999856535761,2407.999965453811,86.0,0.9999999377618786,2407.9998501306036,82.0,nonessential
286,HNEAP_RS01460,WP_012823198.1,502585413.0,308958,310787,1829.0,-,DNA helicase RecQ,0.5842,34,0.9922131259427069,2389.2492072700384,93.0,0.987701087392036,2378.384218440023,89.0,nonessential
287,HNEAP_RS01465,WP_012823199.1,502585414.0,310900,311427,527.0,+,hypothetical protein,0.5492,8,0.9999996716396874,2407.9992093083674,46.0,0.9999998609761999,2407.999665230689,46.0,nonessential
288,HNEAP_RS01470,WP_012823200.1,502585415.0,311494,312861,1367.0,+,UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase,0.5877,21,0.9992518428954229,2406.1984376921782,78.0,0.9998761124509884,2407.7016787819803,80.0,nonessential
289,HNEAP_RS01475,WP_012823201.1,502585416.0,312896,313486,590.0,+,peptidase S16,0.577,12,0.2760635479182983,664.7610233872623,20.0,0.2514555183741658,605.5048882449912,19.0,nonessential
290,HNEAP_RS01480,WP_012823202.1,502585417.0,313660,314040,380.0,+,thiol reductase thioredoxin,0.5354,4,0.5595692886020251,1347.4428469536765,15.0,0.7018751540176842,1690.1153708745835,16.0,nonessential
291,HNEAP_RS01485,WP_012823203.1,502585418.0,314071,314985,914.0,+,AEC family transporter,0.5552,18,0.9542213752347435,2297.765071565262,46.0,0.9412910954487691,2266.628957840636,44.0,nonessential
292,HNEAP_RS01490,WP_012823204.1,502585419.0,315048,315608,560.0,+,FKBP-type peptidylprolyl isomerase,0.5651,5,0.9090622927646709,2189.0220009773275,28.0,0.7473397132991386,1799.5940296243257,24.0,nonessential
293,HNEAP_RS01495,WP_012823205.1,502585420.0,315601,317409,1808.0,+,peptidase M61 domain-containing protein,0.5871,26,0.02181293002893393,52.5255355096729,55.0,0.051102043006697656,123.05371956012796,56.0,nonessential
294,HNEAP_RS12125,WP_081441082.1,1174219901.0,317310,318233,923.0,+,biotin--[acetyl-CoA-carboxylase] ligase,0.5963,11,5.701872785553841e-12,1.373010966761365e-08,4.0,1.5854581828790762e-11,3.817783304372816e-08,4.0,essential
295,HNEAP_RS01505,WP_012823207.1,502585422.0,318234,319001,767.0,+,type III pantothenate kinase,0.5833,8,3.236578554192792e-14,7.793681158496244e-11,0.0,8.38935897972748e-14,2.020157642318377e-10,0.0,essential
296,HNEAP_RS01530,WP_012823208.1,502585423.0,319633,320823,1190.0,+,elongation factor Tu,0.5592,30,1.1605772912481189e-12,2.7946701173254703e-09,8.0,3.9688718820819384e-12,9.557043492053307e-09,8.0,essential
297,HNEAP_RS01540,WP_012823209.1,502585424.0,321067,321441,374.0,+,preprotein translocase subunit SecE,0.5413,6,2.643188027862392e-07,0.000636479677109264,0.0,4.205581246808277e-07,0.001012703964231433,0.0,essential
298,HNEAP_RS01545,WP_012823210.1,502585425.0,321454,321987,533.0,+,transcription termination/antitermination protein NusG,0.5206,11,4.2233112450491573e-10,1.016973347807837e-06,0.0,8.186526263376754e-10,1.9713155242211223e-06,0.0,essential
299,HNEAP_RS01550,WP_012823211.1,502585426.0,322062,322493,431.0,+,50S ribosomal protein L11,0.5255,13,2.6279564488818132e-08,6.328119128907406e-05,0.0,4.488034610290027e-08,0.00010807187341578385,0.0,essential
300,HNEAP_RS01555,WP_012823212.1,502585428.0,322493,323188,695.0,+,50S ribosomal protein L1,0.5417,11,5.976052998158998e-13,1.4390335619566867e-09,0.0,1.416535656501136e-12,3.4110178608547357e-09,0.0,essential
301,HNEAP_RS01560,WP_012823213.1,502585429.0,323424,323951,527.0,+,50S ribosomal protein L10,0.5492,7,5.384934760688834e-10,1.2966922903738714e-06,0.0,1.0360750619784375e-09,2.4948687492440773e-06,0.0,essential
302,HNEAP_RS01565,WP_012823214.1,502585430.0,323983,324360,377.0,+,50S ribosomal protein L7/L12,0.4894,4,2.3408003831232981e-07,0.0005636647322560901,0.0,3.7383524747495e-07,0.0009001952759196796,0.0,essential
303,HNEAP_RS01570,WP_012823215.1,502585431.0,324553,328719,4166.0,+,DNA-directed RNA polymerase subunit beta,0.5476,77,4.6332298638788484e-68,1.1156817512220268e-64,3.0,7.438078637445456e-66,1.791089335896866e-62,3.0,essential
304,HNEAP_RS01575,WP_012823216.1,502585432.0,328797,333002,4205.0,+,DNA-directed RNA polymerase subunit beta',0.5573,84,1.1038508357102497e-74,2.658072812390281e-71,0.0,2.0448633563774312e-72,4.924030962156854e-69,0.0,essential
305,HNEAP_RS01580,WP_012823217.1,502585433.0,333122,333499,377.0,+,30S ribosomal protein S12,0.5423,16,2.3408003831232981e-07,0.0005636647322560901,0.0,3.7383524747495e-07,0.0009001952759196796,0.0,essential
306,HNEAP_RS01585,WP_012823218.1,502585434.0,333527,333997,470.0,+,30S ribosomal protein S7,0.5287,12,5.416145726588819e-09,1.3042078909625875e-05,0.0,9.708699306712034e-09,2.3378547930562578e-05,0.0,essential
307,HNEAP_RS01590,WP_012823219.1,502585435.0,334015,336114,2099.0,+,elongation factor G,0.5357,45,1.2106338713185451e-37,2.915206362135057e-34,0.0,1.640598172858669e-36,3.950560400243675e-33,0.0,essential
308,HNEAP_RS01595,WP_012823220.1,502585436.0,336147,337337,1190.0,+,elongation factor Tu,0.5508,33,1.1760003716350139e-21,2.8318088948971134e-18,0.0,5.1543478425493224e-21,1.2411669604858769e-17,0.0,essential
309,HNEAP_RS01600,WP_012823221.1,502585437.0,337343,337654,311.0,+,30S ribosomal protein S10,0.5128,3,3.389731589983961e-06,0.008162473668681378,0.0,4.987551792005968e-06,0.01201002471515037,0.0,essential
310,HNEAP_RS01605,WP_012823222.1,502585438.0,337802,338446,644.0,+,50S ribosomal protein L3,0.5426,18,4.71408031896153e-12,1.1351505408059364e-08,0.0,1.0488316392216421e-11,2.5255865872457142e-08,0.0,essential
311,HNEAP_RS01610,WP_012823223.1,502585439.0,338455,339063,608.0,+,50S ribosomal protein L4,0.5238,15,5.292563977549742e-10,1.274449405793978e-06,1.0,1.0921936138957708e-09,2.6300022222610158e-06,1.0,essential
312,HNEAP_RS01615,WP_012823224.1,502585440.0,339060,339353,293.0,+,50S ribosomal protein L23,0.517,5,7.02663480829533e-06,0.016920136618375155,0.0,1.0110254819482885e-05,0.024345493605314787,0.0,essential
313,HNEAP_RS01620,WP_012823225.1,502585441.0,339383,340207,824.0,+,50S ribosomal protein L2,0.5539,24,3.2179275156153725e-15,7.748769457601817e-12,0.0,8.952801348859737e-15,2.155834564805425e-11,0.0,essential
314,HNEAP_RS12435,WP_012823226.1,502585442.0,340232,340507,275.0,+,30S ribosomal protein S19,0.5399,5,1.4565636074265443e-05,0.03507405166683119,0.0,2.0494474398984764e-05,0.04935069435275531,0.0,essential
315,HNEAP_RS01630,WP_012823227.1,502585443.0,340517,340849,332.0,+,50S ribosomal protein L22,0.5465,2,1.4481700450341268e-06,0.0034871934684421774,0.0,2.1870915106479613e-06,0.00526651635764029,0.0,essential
316,HNEAP_RS01635,WP_012823228.1,502585444.0,340860,341534,674.0,+,30S ribosomal protein S3,0.5437,12,1.3988147110721759e-12,3.3683458242617994e-09,0.0,3.2303380620454504e-12,7.778654053405444e-09,0.0,essential
317,HNEAP_RS01640,WP_012823229.1,502585445.0,341566,341979,413.0,+,50S ribosomal protein L16,0.5145,10,5.4475375905749834e-08,0.0001311767051810456,0.0,9.097684683980207e-08,0.00021907224719024338,0.0,essential
318,HNEAP_RS01645,WP_012823230.1,502585446.0,341979,342176,197.0,+,50S ribosomal protein L29,0.4646,1,0.00034291390850638696,0.8257366916833798,0.0,0.00043795256940211023,1.0545897871202814,0.0,ambiguous
319,HNEAP_RS01650,WP_012823231.1,502585447.0,342178,342447,269.0,+,30S ribosomal protein S17,0.4926,8,1.857192033852629e-05,0.04472118417517131,0.0,2.593751384898774e-05,0.06245753334836247,0.0,ambiguous
320,HNEAP_RS01655,WP_012823232.1,502585448.0,342460,342828,368.0,+,50S ribosomal protein L14,0.5149,10,3.370197994987483e-07,0.0008115436771929859,0.0,5.322523510899915e-07,0.0012816636614246995,0.0,essential
321,HNEAP_RS01660,WP_012823233.1,502585449.0,342839,343162,323.0,+,50S ribosomal protein L24,0.4691,9,2.085021780312084e-06,0.0050207324469914985,0.0,3.1138973824808796e-06,0.007498264897013958,0.0,essential
322,HNEAP_RS01665,WP_012823234.1,502585450.0,343174,343713,539.0,+,50S ribosomal protein L5,0.5,14,3.312270002371776e-10,7.975946165711236e-07,0.0,6.468567261234991e-10,1.557630996505386e-06,0.0,essential
323,HNEAP_RS01670,WP_012823235.1,502585451.0,343725,344030,305.0,+,30S ribosomal protein S14,0.5163,3,4.32207867457261e-06,0.010407565448370846,0.0,6.312174255325463e-06,0.015199715606823715,0.0,essential
324,HNEAP_RS01675,WP_012823236.1,502585452.0,344043,344435,392.0,+,30S ribosomal protein S8,0.5038,10,1.2751051108754277e-07,0.000307045310698803,0.0,2.0746810697119665e-07,0.0004995832015866415,0.0,essential
325,HNEAP_RS01680,WP_012823237.1,502585453.0,344449,344976,527.0,+,50S ribosomal protein L6,0.4905,14,5.384934760688834e-10,1.2966922903738714e-06,0.0,1.0360750619784375e-09,2.4948687492440773e-06,0.0,essential
326,HNEAP_RS01685,WP_012823238.1,502585454.0,344986,345342,356.0,+,50S ribosomal protein L18,0.5406,8,5.479111401128739e-07,0.0013193700253918003,0.0,8.525124117491939e-07,0.002052849887492059,0.0,essential
327,HNEAP_RS01690,WP_012823239.1,502585455.0,345354,345869,515.0,+,30S ribosomal protein S5,0.5136,15,8.754576878126184e-10,2.1081021122527854e-06,0.0,1.6594888646928559e-09,3.996049186180397e-06,0.0,essential
328,HNEAP_RS01695,WP_012823240.1,502585456.0,345866,346057,191.0,+,50S ribosomal protein L30,0.4688,5,0.00043723252175751503,1.0528559123920962,0.0,0.000554266511691059,1.33467376015207,0.0,ambiguous
329,HNEAP_RS01700,WP_012823241.1,502585457.0,346057,346485,428.0,+,50S ribosomal protein L15,0.5431,6,2.967439288505232e-08,7.145593806720598e-05,0.0,5.048960556702721e-08,0.00012157897020540151,0.0,essential
330,HNEAP_RS01705,WP_012823242.1,502585458.0,346489,347823,1334.0,+,preprotein translocase subunit SecY,0.5079,54,3.4494581681585215e-24,8.30629526892572e-21,0.0,1.8079077160626738e-23,4.353441780278919e-20,0.0,essential
331,HNEAP_RS01710,WP_012823243.1,502585459.0,347900,348256,356.0,+,30S ribosomal protein S13,0.5294,7,8.609362784616608e-06,0.020731345585356793,1.0,8.525124117491939e-07,0.002052849887492059,0.0,essential
332,HNEAP_RS01715,WP_012823244.1,502585460.0,348299,348688,389.0,+,30S ribosomal protein S11,0.5359,7,1.4398248512054138e-07,0.0003467098241702636,0.0,2.3339799708087836e-07,0.0005620223769707551,0.0,essential
333,HNEAP_RS01720,WP_012823245.1,502585461.0,348702,349325,623.0,+,30S ribosomal protein S4,0.492,12,1.1034247690525183e-11,2.6570468438784642e-08,0.0,2.3918076112703026e-11,5.759472727938889e-08,0.0,essential
334,HNEAP_RS01725,WP_012823246.1,502585462.0,349342,350337,995.0,+,DNA-directed RNA polymerase subunit alpha,0.504,25,3.16261679451243e-18,7.615581241185931e-15,0.0,1.0880515150938812e-17,2.620028048346066e-14,0.0,essential
335,HNEAP_RS01730,WP_012823247.1,502585463.0,350367,350747,380.0,+,50S ribosomal protein L17,0.5354,8,2.0730066782503761e-07,0.0004991800081226906,0.0,3.3230315633711524e-07,0.0008001860004597735,0.0,essential
336,HNEAP_RS01735,WP_012823248.1,502585464.0,350881,351531,650.0,+,hypothetical protein,0.5223,12,0.25943930320892633,624.7298421270946,22.0,0.3118224716239752,750.8685116705323,22.0,nonessential
337,HNEAP_RS01740,WP_012823249.1,502585465.0,351594,353633,2039.0,-,excinuclease ABC subunit UvrB,0.5549,44,0.9999967559234865,2407.9921882637555,123.0,0.9999979901126248,2407.9951601912007,121.0,nonessential
338,HNEAP_RS01745,WP_012823250.1,502585466.0,353784,356195,2411.0,+,ribonuclease R,0.5717,31,1.0420593180244904e-28,2.5092788378029727e-25,11.0,1.4726070736764425e-27,3.546037833412873e-24,11.0,essential
339,HNEAP_RS01750,WP_012823251.1,502585467.0,356195,357001,806.0,+,23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB,0.5911,11,0.998451014784198,2404.270043600349,49.0,0.9997294126426416,2407.348425643481,51.0,nonessential
340,HNEAP_RS01755,WP_012823252.1,502585468.0,357115,358290,1175.0,+,pyridoxal phosphate-dependent aminotransferase,0.5816,20,2.1588668236036243e-21,5.198551311237527e-18,0.0,9.28758125488133e-21,2.2364495661754243e-17,0.0,essential
341,HNEAP_RS01760,WP_012823253.1,502585469.0,358362,359411,1049.0,+,recombinase RecA,0.5705,21,0.7822472924468205,1883.6514802119436,46.0,0.6412154498396871,1544.0468032139665,42.0,nonessential
342,HNEAP_RS01765,WP_012823254.1,502585470.0,359427,359933,506.0,+,regulatory protein RecX,0.5779,10,0.638317671704351,1537.0689534640774,21.0,0.5162318756728415,1243.0863566202022,19.0,nonessential
343,HNEAP_RS01770,WP_041600556.1,753844939.0,360107,362722,2615.0,+,alanine--tRNA ligase,0.5826,43,1.0177944736463988e-46,2.4508490925405284e-43,0.0,2.617748820818452e-45,6.303539160530832e-42,0.0,essential
344,HNEAP_RS01775,WP_012823257.1,502585473.0,362922,364154,1232.0,+,aspartate kinase,0.5312,33,2.1464261836697096e-22,5.16859425027666e-19,0.0,9.911349626029118e-22,2.3866529899478117e-18,0.0,essential
345,HNEAP_RS01780,WP_012823258.1,502585474.0,364233,364448,215.0,+,carbon storage regulator,0.4815,5,0.06899001502922401,166.12795619037144,4.0,0.032689194429635804,78.71558018656302,3.0,nonessential
346,HNEAP_RS01785,WP_012823259.1,502585475.0,364525,365724,1199.0,+,ammonium transporter,0.5517,23,0.14650750760615447,352.79007831561995,40.0,0.1996512021462775,480.7600947682362,40.0,nonessential
347,HNEAP_RS12440,WP_081441173.1,1174219992.0,366741,366911,170.0,+,AlpA family phage regulatory protein,0.5263,3,0.033325300980831335,80.24732476184185,2.0,0.03897119716439444,93.84264277186182,2.0,nonessential
348,HNEAP_RS12445,WP_012823260.1,502585476.0,367010,369424,2414.0,-,relaxase,0.5395,48,0.999979708995011,2407.9511392599866,137.0,0.9999888201906535,2407.973079019094,135.0,nonessential
349,HNEAP_RS01810,WP_012823261.1,502585477.0,369414,369818,404.0,-,hypothetical protein,0.5383,6,0.9999823455533279,2407.9574880924133,34.0,0.9999470313198543,2407.872451418209,32.0,nonessential
350,HNEAP_RS01815,WP_012823262.1,502585478.0,370195,371868,1673.0,-,hypothetical protein,0.601,30,1.286643349098031e-07,0.0003098237184628059,29.0,1.7945928662896429e-07,0.000432137962202546,28.0,essential
351,HNEAP_RS01820,WP_012823263.1,502585479.0,372103,372546,443.0,-,hypothetical protein,0.3806,17,0.9963853841590878,2399.2960050550837,29.0,0.992043601976725,2388.840993559954,27.0,nonessential
352,HNEAP_RS01825,WP_012823264.1,502585480.0,372550,372795,245.0,-,hypothetical protein,0.4553,13,0.6182856601079993,1488.8318695400624,10.0,0.2708045896246378,652.0974518161279,7.0,nonessential
353,HNEAP_RS01830,WP_041600329.1,753844712.0,372792,376835,4043.0,-,hypothetical protein,0.5883,78,2.2375491936532548e-35,5.388018458317038e-32,33.0,2.441903817762378e-34,5.880104393171806e-31,32.0,essential
354,HNEAP_RS01845,WP_012823266.1,502585482.0,378521,378835,314.0,-,hypothetical protein,0.4603,12,0.00029393059979702094,0.7077848843112264,2.0,6.016841064383363e-05,0.14488553283035138,1.0,nonessential
355,HNEAP_RS01850,WP_081441083.1,1174219902.0,378823,386097,7274.0,-,hypothetical protein,0.5783,140,0.451161297166469,1086.3964035768574,286.0,0.5155280595474188,1241.3915673901843,280.0,nonessential
356,HNEAP_RS01855,WP_012823268.1,502585484.0,386116,387873,1757.0,-,ShlB/FhaC/HecB family hemolysin secretion/activation protein,0.5387,57,0.49614352539990125,1194.7136091629623,69.0,0.5008837276394568,1206.1280161558118,67.0,nonessential
357,HNEAP_RS01860,WP_012823269.1,502585485.0,388197,388487,290.0,-,addiction module antidote protein  HigA family,0.5464,7,0.7351368322222527,1770.2094919911844,13.0,0.672517162776838,1619.421327966626,12.0,nonessential
358,HNEAP_RS01870,WP_049772441.1,908628408.0,388762,389103,341.0,-,hypothetical protein,0.5468,6,0.999949386457435,2407.8781225895036,29.0,0.9996104761930739,2407.062026672922,26.0,nonessential
359,HNEAP_RS01875,WP_049772442.1,908628409.0,389193,389444,251.0,-,hypothetical protein,0.6389,4,0.4602626050048299,1108.3123528516305,9.0,0.6260540707014386,1507.5382022490642,10.0,nonessential
360,HNEAP_RS01885,WP_012823270.1,502585486.0,389710,390156,446.0,-,DUF302 domain-containing protein,0.5145,8,0.7577832157912731,1824.7419836253855,20.0,0.7254621989308188,1746.9129750254115,19.0,nonessential
361,HNEAP_RS12450,WP_012823272.1,502585488.0,391181,391453,272.0,+,YkgJ family cysteine cluster protein,0.5238,5,0.9998972254567685,2407.7525188998984,24.0,0.9998349931816489,2407.6026635814105,23.0,nonessential
362,HNEAP_RS01890,WP_012823273.1,502585489.0,391719,393110,1391.0,-,aromatic hydrocarbon degradation membrane protein,0.5345,36,0.26300671442147017,633.3201683269002,50.0,0.24429532538701573,588.2631435319339,48.0,nonessential
363,HNEAP_RS01895,WP_012823274.1,502585490.0,393520,394365,845.0,-,diaminopimelate epimerase,0.5485,11,6.833092327630645e-10,1.6454086324934593e-06,5.0,1.6731495106654183e-09,4.028944021682327e-06,5.0,essential
364,HNEAP_RS01900,WP_012823275.1,502585491.0,394554,394997,443.0,+,hypothetical protein,0.5473,9,0.9999999994399507,2407.9999986514013,47.0,0.9999999993629924,2407.999998466086,46.0,nonessential
365,HNEAP_RS01905,WP_012823276.1,502585493.0,395075,396916,1841.0,+,translational GTPase TypA,0.5581,35,0.6646016621092816,1600.36080235915,76.0,0.6313002233153174,1520.1709377432844,73.0,nonessential
366,HNEAP_RS01910,WP_012823277.1,502585494.0,396964,398319,1355.0,+,signal recognition particle protein,0.5789,22,1.4736865908457073e-24,3.548637310756463e-21,0.0,7.927856757644448e-24,1.909027907240783e-20,0.0,essential
367,HNEAP_RS01920,WP_012823278.1,502585495.0,398612,399910,1298.0,+,trigger factor,0.5566,12,0.0033913453525331477,8.16635960889982,33.0,0.002335765327061163,5.62452290756328,31.0,nonessential
368,HNEAP_RS01925,WP_012823279.1,502585496.0,400076,400708,632.0,+,ATP-dependent Clp endopeptidase  proteolytic subunit ClpP,0.5197,11,0.2371439898522194,571.0427275641443,21.0,0.158688665608932,382.12230678630823,19.0,nonessential
369,HNEAP_RS01930,WP_012823280.1,502585497.0,400769,402073,1304.0,+,ATP-dependent Clp protease ATP-binding subunit ClpX,0.5525,18,0.23097412176607357,556.1856852127052,46.0,0.3028423715255306,729.2444306334777,46.0,nonessential
370,HNEAP_RS01935,WP_012823282.1,502585499.0,402313,404745,2432.0,+,endopeptidase La,0.5614,38,0.9664581561658742,2327.2312400474248,114.0,0.9502206042756564,2288.1312150957806,109.0,nonessential
371,HNEAP_RS01940,WP_012823283.1,502585500.0,405027,405299,272.0,+,HU family DNA-binding protein,0.5311,3,0.15160163160501697,365.05672890488086,7.0,0.17550453901504767,422.6149299482348,7.0,nonessential
372,HNEAP_RS01945,WP_012823284.1,502585501.0,405502,407439,1937.0,+,peptidyl-prolyl cis-trans isomerase,0.5624,31,2.4270850955277857e-11,5.8444209100309084e-08,27.0,1.3367350872466812e-11,3.2188580900900083e-08,25.0,essential
373,HNEAP_RS01950,WP_012823285.1,502585502.0,407619,408407,788.0,-,enoyl-ACP reductase,0.5779,12,1.3827396022833897e-14,3.329636962298402e-11,0.0,3.678818099442857e-14,8.8585939834584e-11,0.0,essential
374,HNEAP_RS01955,WP_012823286.1,502585503.0,408537,410513,1976.0,+,ABC transporter substrate-binding protein,0.5665,46,0.9998967295007956,2407.751324637916,112.0,0.9998889175590624,2407.732513482222,109.0,nonessential
375,HNEAP_RS01960,WP_012823287.1,502585504.0,410515,411264,749.0,+,hypothetical protein,0.596,19,0.9617772178923764,2315.959540684842,39.0,0.9622174399157312,2317.0195953170805,38.0,nonessential
376,HNEAP_RS01965,WP_012823288.1,502585505.0,411276,411950,674.0,+,FMN-binding negative transcriptional regulator,0.5778,14,0.978933477887377,2357.2718147528035,37.0,0.9785052909909199,2356.240740706135,36.0,nonessential
377,HNEAP_RS01970,WP_012823289.1,502585506.0,411947,413011,1064.0,+,microcin C ABC transporter permease YejB,0.5502,24,0.9999327456448523,2407.8380515128047,68.0,0.9999729513423024,2407.934866832264,68.0,nonessential
378,HNEAP_RS01975,WP_012823290.1,502585507.0,413008,414048,1040.0,+,ABC transporter permease,0.5783,26,0.7988992477226329,1923.7493885161,46.0,0.8510460387838847,2049.3188613915945,46.0,nonessential
379,HNEAP_RS01980,WP_012823291.1,502585508.0,414118,414513,395.0,-,YkgJ family cysteine cluster protein,0.6111,8,0.9998625384130985,2407.6689924987413,31.0,0.9996110533412494,2407.0634164457288,29.0,nonessential
380,HNEAP_RS01985,WP_012823292.1,502585509.0,414775,415542,767.0,+,ABC transporter substrate-binding protein,0.5065,24,0.5882644562041872,1416.5408105396828,31.0,0.6536851233426038,1574.0737770089897,31.0,nonessential
381,HNEAP_RS01990,WP_012823293.1,502585510.0,416111,416392,281.0,+,DUF1255 domain-containing protein,0.5284,3,0.9907831581635951,2385.805844857937,19.0,0.9932693871780794,2391.792684324815,19.0,nonessential
382,HNEAP_RS01995,WP_012823294.1,502585511.0,416802,418271,1469.0,+,D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase,0.551,31,0.4653823024707651,1120.6405843496025,57.0,0.34601281936752304,833.1988690369955,53.0,nonessential
383,HNEAP_RS02000,WP_012823295.1,502585512.0,418294,419646,1352.0,-,metal-dependent phosphohydrolase,0.5772,22,0.5549742688508688,1336.3780393928919,54.0,0.7398280219859854,1781.5058769422528,56.0,nonessential
384,HNEAP_RS02005,WP_081441174.1,1174219993.0,419701,421428,1727.0,-,single-stranded-DNA-specific exonuclease RecJ,0.588,24,0.16073395117261086,387.04735442364694,60.0,0.19245051892386092,463.4208495686571,59.0,nonessential
385,HNEAP_RS02010,WP_012823297.1,502585514.0,421502,423019,1517.0,-,exopolyphosphatase,0.5731,28,0.3184421406223708,766.8086746186689,56.0,0.356050497064821,857.3695969320889,55.0,nonessential
386,HNEAP_RS02015,WP_012823298.1,502585515.0,423167,424231,1064.0,-,fructose-bisphosphate aldolase class II,0.5615,18,1.9341135313318675e-19,4.657345383447137e-16,0.0,7.249307231307133e-19,1.7456331812987577e-15,0.0,essential
387,HNEAP_RS02020,WP_012823299.1,502585516.0,424313,425788,1475.0,-,pyruvate kinase,0.5542,30,1.1425046724899994e-26,2.751151251355919e-23,0.0,7.133859857006048e-26,1.7178334535670562e-22,0.0,essential
388,HNEAP_RS02025,WP_012823300.1,502585517.0,425798,426997,1199.0,-,phosphoglycerate kinase,0.5567,13,8.168013050184624e-22,1.9668575424844575e-18,0.0,3.6202318267742334e-21,8.717518238872353e-18,0.0,essential
389,HNEAP_RS02030,WP_012823301.1,502585518.0,427153,428151,998.0,-,type I glyceraldehyde-3-phosphate dehydrogenase,0.5415,13,2.800805136157452e-18,6.744338767867145e-15,0.0,9.671719164130045e-18,2.3289499747225148e-14,0.0,essential
390,HNEAP_RS02035,WP_012823302.1,502585519.0,428269,430257,1988.0,-,transketolase,0.5726,30,1.0845983302005615e-35,2.6117127791229523e-32,0.0,1.2805487103461772e-34,3.0835612945135945e-31,0.0,essential
391,HNEAP_RS02040,WP_012823303.1,502585520.0,430447,430998,551.0,-,thioredoxin family protein,0.5199,18,0.9999999999999999,2407.9999999999995,84.0,0.9999999999999999,2407.9999999999995,79.0,nonessential
392,HNEAP_RS02045,WP_012823304.1,502585521.0,431225,432082,857.0,+,hypothetical protein,0.5513,16,0.9999998041044799,2407.9995282835876,66.0,0.9999999342275698,2407.9998416199883,66.0,nonessential
393,HNEAP_RS02050,WP_041600331.1,753844714.0,432170,433252,1082.0,+,IS630 family transposase,0.5946,12,0.9999999821941574,2407.999957123531,82.0,0.9999999578708166,2407.9998985529264,79.0,nonessential
394,HNEAP_RS02055,WP_012823306.1,502585523.0,433325,434497,1172.0,+,methionine adenosyltransferase,0.5772,20,1.20516099781036e-19,2.9020276827273467e-16,1.0,5.007151223783178e-19,1.2057220146869893e-15,1.0,essential
395,HNEAP_RS02060,WP_012823307.1,502585524.0,434628,436040,1412.0,+,adenosylhomocysteinase,0.5548,21,8.696853015389574e-24,2.0942022061058094e-20,1.0,4.8673465162668076e-23,1.1720570411170473e-19,1.0,essential
396,HNEAP_RS02065,WP_041600332.1,753844715.0,436040,436909,869.0,+,methylenetetrahydrofolate reductase [NAD(P)H],0.577,14,5.20140986705602e-16,1.2524994959870896e-12,0.0,1.5302847144486791e-15,3.6849255923924195e-12,0.0,essential
397,HNEAP_RS02070,WP_012823309.1,502585526.0,437084,437998,914.0,+,SPFH/Band 7/PHB domain protein,0.553,13,0.12340397957753808,297.1567828227117,29.0,0.12306630793864211,296.3436695162502,28.0,nonessential
398,HNEAP_RS02075,WP_012823310.1,502585527.0,438038,438391,353.0,+,hypothetical protein,0.5424,4,0.46120921862920744,1110.5917984591315,13.0,0.5073345301283112,1221.6615485489733,13.0,nonessential
399,HNEAP_RS02080,WP_012823311.1,502585528.0,438432,438884,452.0,+,NfeD family protein,0.5894,10,0.2867158330575467,690.4117260025725,15.0,0.33203195624349235,799.5329506343296,15.0,nonessential
400,HNEAP_RS02085,WP_012823312.1,502585529.0,438898,440259,1361.0,+,adenosylmethionine--8-amino-7-oxononanoate transaminase,0.5808,29,3.27226713820248e-15,7.879619268791572e-12,8.0,2.73611021274722e-17,6.588553392295306e-14,5.0,essential
401,HNEAP_RS02090,WP_012823313.1,502585530.0,440276,441010,734.0,+,16S rRNA (uracil(1498)-N(3))-methyltransferase,0.6041,12,0.9706435786075975,2337.309737287095,39.0,0.9572541719425285,2305.0680460376084,37.0,nonessential
402,HNEAP_RS02095,WP_081441084.1,1174219903.0,441043,442227,1184.0,+,peptide chain release factor 2,0.546,20,1.8685635663574316e-18,4.4995010677886955e-15,2.0,7.638672483916836e-18,1.839392334127174e-14,2.0,essential
403,HNEAP_RS02100,WP_012823315.1,502585532.0,442272,443807,1535.0,+,lysine--tRNA ligase,0.5671,34,1.005968568460981e-27,2.4223723128540425e-24,0.0,6.767199235720903e-27,1.6295415759615936e-23,0.0,essential
404,HNEAP_RS02105,WP_012823316.1,502585533.0,444379,445509,1130.0,+,iron-sulfur cluster carrier protein ApbC,0.5703,20,0.004157597753504742,10.01149539043942,28.0,4.2932079209468074e-05,0.10338044673639912,20.0,nonessential
405,HNEAP_RS02110,WP_012823317.1,502585534.0,445496,445978,482.0,+,hypothetical protein,0.5714,7,0.9999376405352046,2407.849838408773,37.0,0.9998469529096342,2407.631462606399,35.0,nonessential
406,HNEAP_RS02115,WP_012823318.1,502585535.0,446044,446544,500.0,+,lipid hydroperoxide peroxidase,0.5749,7,0.8019903399379713,1931.192738570635,23.0,0.8391710394089377,2020.7238628967218,23.0,nonessential
407,HNEAP_RS02120,WP_012823319.1,502585536.0,446561,447502,941.0,+,fructokinase,0.5924,13,0.9750287299993421,2347.869181838416,49.0,0.9845836442291204,2370.877415303722,49.0,nonessential
408,HNEAP_RS02125,WP_012823320.1,502585538.0,447499,448800,1301.0,+,arsenical efflux pump membrane protein ArsB,0.5591,32,0.9894265357265725,2382.5390980295865,68.0,0.9944417702995304,2394.6157828812693,68.0,nonessential
409,HNEAP_RS02130,WP_012823321.1,502585539.0,448808,450313,1505.0,+,exodeoxyribonuclease VII large subunit,0.6069,19,0.9784208416802189,2356.0373867659673,75.0,0.9712851931669312,2338.8547451459704,72.0,nonessential
410,HNEAP_RS02135,WP_012823322.1,502585540.0,450375,450752,377.0,-,cytoplasmic domain of flagellar protein FhlB-like protein,0.5556,7,0.9973768291808283,2401.6834046674344,26.0,0.9982741538383199,2403.844162442674,26.0,nonessential
411,HNEAP_RS02140,WP_012823323.1,502585541.0,450780,452120,1340.0,-,flagellar hook-length control protein FliK,0.5936,13,0.996664319431867,2399.9676811919358,73.0,0.9976344094110353,2402.303657861773,72.0,nonessential
412,HNEAP_RS02145,WP_012823324.1,502585542.0,452328,453797,1469.0,+,sigma-54-dependent Fis family transcriptional regulator,0.581,17,0.9931684248373666,2391.5495670083787,77.0,0.995224052264582,2396.4995178531135,76.0,nonessential
413,HNEAP_RS02150,WP_012823325.1,502585543.0,453896,454237,341.0,+,flagellar hook-basal body complex protein FliE,0.5439,3,0.9110996078509486,2193.9278557050843,18.0,0.9289685902579493,2236.956365341142,18.0,nonessential
414,HNEAP_RS02155,WP_012823326.1,502585544.0,454266,456038,1772.0,+,flagellar M-ring protein FliF,0.5623,28,0.8669905621083047,2087.713273556798,79.0,0.8961326813328964,2157.8874966496146,78.0,nonessential
415,HNEAP_RS02160,WP_012823327.1,502585545.0,456040,457080,1040.0,+,flagellar motor switch protein FliG,0.5524,16,0.9995202965588634,2406.844874113743,63.0,0.9993977083761051,2406.549681769661,61.0,nonessential
416,HNEAP_RS02165,WP_012823328.1,502585546.0,457064,457846,782.0,+,flagellar assembly protein FliH,0.6207,6,0.2639128370648921,635.5021116522602,27.0,0.25658822901753237,617.864455474218,26.0,nonessential
417,HNEAP_RS02170,WP_012823329.1,502585547.0,457843,459240,1397.0,+,flagellar protein export ATPase FliI,0.6044,24,0.9996166333803524,2407.0768531798885,81.0,0.9998475426123139,2407.632882610452,81.0,nonessential
418,HNEAP_RS02175,WP_081441085.1,1174219904.0,459237,459713,476.0,+,hypothetical protein,0.5304,10,0.9999999979193209,2407.9999949897247,48.0,0.9999999823701795,2407.999957547392,45.0,nonessential
419,HNEAP_RS02180,WP_012823331.1,502585549.0,459731,461245,1514.0,+,flagellar hook-length control protein FliK,0.5307,30,0.9996690771078348,2407.2031376756663,87.0,0.9996938128786509,2407.2627014117916,85.0,nonessential
420,HNEAP_RS02185,WP_012823332.1,502585550.0,461578,461901,323.0,+,histone family protein nucleoid-structuring protein H-NS,0.4907,9,0.7831918693403555,1885.9260213715759,15.0,0.8153990273984765,1963.4808579755313,15.0,nonessential
421,HNEAP_RS02190,WP_012823333.1,502585551.0,462170,463372,1202.0,-,hypothetical protein,0.5561,14,0.009250673083767614,22.275620785712412,32.0,0.0007117001205405492,1.7137738902616426,26.0,nonessential
422,HNEAP_RS02195,WP_012823334.1,502585552.0,464290,464739,449.0,+,division/cell wall cluster transcriptional repressor MraZ,0.5422,4,1.2677572173468143e-08,3.0527593793711284e-05,0.0,2.214019870201623e-08,5.331359847445508e-05,0.0,essential
423,HNEAP_RS02200,WP_012823335.1,502585553.0,464736,465689,953.0,+,16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH,0.5671,12,1.732758645036203e-17,4.1724828172471764e-14,0.0,5.658357530520831e-17,1.362532493349416e-13,0.0,essential
424,HNEAP_RS02205,WP_012823336.1,502585554.0,465686,465946,260.0,+,cell division protein FtsL,0.5747,2,2.673916543214769e-05,0.06438791036061163,0.0,3.692884183821646e-05,0.08892465114642524,0.0,ambiguous
425,HNEAP_RS02210,WP_081441175.1,1174219994.0,465988,467802,1814.0,+,hypothetical protein,0.5901,47,1.24612696723742e-32,3.000673737107707e-29,0.0,1.1853630183749307e-31,2.854354148246833e-28,0.0,essential
426,HNEAP_RS02215,WP_012823338.1,502585556.0,467799,469358,1559.0,+,UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2 6-diaminopimelate ligase,0.5821,30,3.806054317676367e-28,9.164978796964692e-25,0.0,2.6378051915726806e-27,6.3518349013070146e-24,0.0,essential
427,HNEAP_RS02220,WP_012823339.1,502585557.0,469355,470779,1424.0,+,UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase,0.567,21,5.3941254905012654e-24,1.2989054181127047e-20,1.0,3.0642261743791015e-23,7.378656627904877e-20,1.0,essential
428,HNEAP_RS02225,WP_012823340.1,502585558.0,470781,471863,1082.0,+,phospho-N-acetylmuramoyl-pentapeptide-transferase,0.5596,19,4.265649543524017e-18,1.0271684100805834e-14,1.0,1.584954945937276e-17,3.8165715098169604e-14,1.0,essential
429,HNEAP_RS02230,WP_012823341.1,502585559.0,471863,473278,1415.0,+,UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase,0.5819,21,2.294424867385131e-22,5.524975080663396e-19,2.0,1.2493051609268982e-21,3.008326827511971e-18,2.0,essential
430,HNEAP_RS02235,WP_012823342.1,502585560.0,473275,474522,1247.0,+,cell division protein FtsW,0.5633,17,3.394874475111842e-15,8.174857736069314e-12,6.0,1.5642267338881021e-15,3.76665797520255e-12,5.0,essential
431,HNEAP_RS02240,WP_012823343.1,502585561.0,474519,475643,1124.0,+,undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase,0.5991,15,1.7029754601480303e-20,4.100764908036457e-17,0.0,6.876712935007978e-20,1.6559124747499212e-16,0.0,essential
432,HNEAP_RS02245,WP_012823344.1,502585562.0,475640,477115,1475.0,+,UDP-N-acetylmuramate--L-alanine ligase,0.5982,22,2.1921953734371453e-23,5.278806459236646e-20,2.0,1.2859154608356928e-22,3.0964844296923483e-19,2.0,essential
433,HNEAP_RS02250,WP_012823345.1,502585563.0,477108,478082,974.0,+,D-alanine--D-alanine ligase,0.5877,13,7.402737055730196e-18,1.782579083019831e-14,0.0,2.4812465584915302e-17,5.974841712847604e-14,0.0,essential
434,HNEAP_RS02255,WP_012823346.1,502585564.0,478085,478900,815.0,+,cell division protein FtsQ,0.5821,12,2.78566552708533e-12,6.7078825892214745e-09,2.0,7.206036614819679e-12,1.7352136168485788e-08,2.0,essential
435,HNEAP_RS02260,WP_012823347.1,502585565.0,478931,480181,1250.0,+,cell division protein FtsA,0.5987,18,1.0354613323243208e-22,2.4933908882369646e-19,0.0,4.889428651515196e-22,1.1773744192848591e-18,0.0,essential
436,HNEAP_RS02265,WP_012823348.1,502585566.0,480248,481393,1145.0,+,cell division protein FtsZ,0.5777,15,7.275496549938501e-21,1.751939569225191e-17,0.0,3.0155076294997156e-20,7.261342371835315e-17,0.0,essential
437,HNEAP_RS02270,WP_041600583.1,753844966.0,481756,482256,500.0,+,hypothetical protein,0.5289,14,0.8563311190468403,2062.0453346647914,24.0,0.9222963995852502,2220.8897302012824,25.0,nonessential
438,HNEAP_RS02275,WP_012823351.1,502585569.0,482560,483021,461.0,-,RES domain-containing protein,0.5823,12,0.7823181368611519,1883.8220735616537,21.0,0.820308975798124,1975.3040137218827,21.0,nonessential
439,HNEAP_RS12130,WP_081441086.1,1174219905.0,483018,483551,533.0,-,hypothetical protein,0.5974,9,4.957137892397435e-06,0.011936788044893024,4.0,8.516709838977839e-06,0.020508237292258636,4.0,essential
440,HNEAP_RS02295,WP_012823353.1,502585571.0,485265,487091,1826.0,-,RNA polymerase sigma factor RpoD,0.5523,24,5.861091285382622e-31,1.4113507815201355e-27,1.0,5.484357355272539e-30,1.3206332511496276e-26,1.0,essential
441,HNEAP_RS02300,WP_012823354.1,502585572.0,487230,488909,1679.0,-,DNA primase,0.5643,27,2.077043705138297e-28,5.001521241973019e-25,1.0,1.619316350752358e-27,3.899313772611678e-24,1.0,essential
442,HNEAP_RS02305,WP_012823355.1,502585573.0,489265,490032,767.0,+,sel1 repeat family protein,0.5573,25,0.9999999999999999,2407.9999999999995,100.0,0.9999999999999999,2407.9999999999995,97.0,nonessential
443,HNEAP_RS02310,WP_012823356.1,502585574.0,490109,491554,1445.0,-,cardiolipin synthase,0.5636,32,0.9999999999911166,2407.9999999786087,113.0,0.9999999999970041,2407.999999992786,112.0,nonessential
444,HNEAP_RS02315,WP_041600587.1,753844970.0,491554,492396,842.0,-,short-chain dehydrogenase/reductase,0.5919,18,0.9999999780339283,2407.9999471056994,68.0,0.9999999931911203,2407.9999836042175,68.0,nonessential
445,HNEAP_RS02320,WP_012823358.1,502585576.0,492545,493210,665.0,+,BAX inhibitor (BI)-1/YccA family protein,0.542,12,0.9416919754056757,2267.594276776867,34.0,0.9396882692199385,2262.769352281612,33.0,nonessential
446,HNEAP_RS02325,WP_012823359.1,502585577.0,493301,493495,194.0,+,hypothetical protein,0.5282,1,0.9128099598468168,2198.046383311135,11.0,0.8692067135473216,2093.0497662219504,10.0,nonessential
447,HNEAP_RS02330,WP_012823360.1,502585579.0,493567,494154,587.0,+,CBS domain-containing protein,0.551,12,0.9534784558638563,2295.976121720166,31.0,0.9498812197948587,2287.3139772660197,30.0,nonessential
448,HNEAP_RS02335,WP_041600334.1,753844717.0,494145,494774,629.0,+,HPP family protein,0.5873,10,0.9544306079680606,2298.2689039870897,33.0,0.9680154219102508,2330.981135959884,33.0,nonessential
449,HNEAP_RS02340,WP_012823362.1,502585581.0,494874,496880,2006.0,+,methyl-accepting chemotaxis protein,0.5481,31,0.9922566626846026,2389.354043744523,101.0,0.9953718770498635,2396.8554799360713,100.0,nonessential
450,HNEAP_RS02345,WP_012823363.1,502585582.0,496904,497485,581.0,+,IclR family transcriptional regulator,0.6031,5,0.46559897542974943,1121.1623328348367,22.0,0.5248112172462178,1263.7454111288926,22.0,nonessential
451,HNEAP_RS02350,WP_012823364.1,502585583.0,497833,498273,440.0,+,DUF3429 domain-containing protein,0.5828,7,0.9893332949024572,2382.314574125117,27.0,0.9871131997995152,2376.9685851172326,26.0,nonessential
452,HNEAP_RS02355,WP_012823365.1,502585584.0,498270,498947,677.0,+,DUF502 domain-containing protein,0.5619,12,0.9292260646036051,2237.576363565481,34.0,0.9271132509987436,2232.4887084049747,33.0,nonessential
453,HNEAP_RS02360,WP_041600588.1,753844971.0,498991,500775,1784.0,+,aspartate--tRNA ligase,0.5916,24,3.138323829227068e-30,7.557083780778779e-27,1.0,2.78739615406622e-29,6.712049938991457e-26,1.0,essential
454,HNEAP_RS02365,WP_012823367.1,502585586.0,500852,501937,1085.0,+,quinolinate synthase NadA,0.5838,11,1.5168804467108423e-14,3.652648115679708e-11,4.0,5.1548212569546875e-14,1.2412809586746887e-10,4.0,essential
455,HNEAP_RS02370,WP_012823368.1,502585587.0,502064,503914,1850.0,+,sodium/hydrogen exchanger,0.5348,57,0.9999999300980245,2407.999831676043,121.0,0.9999999753262498,2407.9999405856097,120.0,nonessential
456,HNEAP_RS02390,WP_012823369.1,502585588.0,504434,505717,1283.0,+,integrase,0.546,30,0.9999998625021878,2407.999668905268,90.0,0.9999997484107706,2407.9993941731354,87.0,nonessential
457,HNEAP_RS02395,WP_012823370.1,502585589.0,505838,506875,1037.0,+,IS5/IS1182 family transposase,0.5645,14,5.772382101561005e-19,1.3899896100558902e-15,0.0,2.0922256911346512e-18,5.0380794642522404e-15,0.0,essential
458,HNEAP_RS02400,WP_012823371.1,502585590.0,507500,507904,404.0,+,hypothetical protein,0.5407,7,0.9999999997486192,2407.999999394675,45.0,0.9999999996928908,2407.9999992604808,44.0,nonessential
459,HNEAP_RS12455,WP_012823372.1,502585591.0,507894,510317,2423.0,+,relaxase,0.5561,47,0.9999999999999999,2407.9999999999995,242.0,0.9999999999999999,2407.9999999999995,237.0,nonessential
460,HNEAP_RS02425,WP_012823373.1,502585592.0,510414,510584,170.0,-,AlpA family phage regulatory protein,0.5439,2,0.9813412139458381,2363.069643181578,12.0,0.9675660263753194,2329.898991511769,11.0,nonessential
461,HNEAP_RS02430,WP_012823375.1,502585594.0,511384,512184,800.0,+,NAD(P)-dependent oxidoreductase,0.5593,13,0.7561810969532119,1820.8840814633343,35.0,0.7567688132403941,1822.2993022828691,34.0,nonessential
462,HNEAP_RS12135,WP_012823376.1,502585595.0,512390,515425,3035.0,+,diguanylate cyclase with PAS/PAC and GAF sensors,0.5461,61,0.9999999986877046,2407.9999968399925,189.0,0.9999999543131787,2407.9998899861343,177.0,nonessential
463,HNEAP_RS02440,WP_012823377.1,502585596.0,515917,516708,791.0,+,ABC transporter permease,0.5391,18,0.1877740412167831,452.1598912500137,26.0,0.09567578279897249,230.38728497992574,23.0,nonessential
464,HNEAP_RS02445,WP_012823378.1,502585597.0,516712,517440,728.0,+,ABC transporter ATP-binding protein,0.5322,16,0.002990858800214986,7.2019879909176865,15.0,0.00046039022857185044,1.1086196704010158,12.0,nonessential
465,HNEAP_RS02450,WP_012823379.1,502585598.0,517445,518881,1436.0,+,mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase,0.5296,33,0.998724801636827,2404.9293223414793,80.0,0.9981279867984574,2403.4921922106855,77.0,nonessential
466,HNEAP_RS02455,WP_012823380.1,502585599.0,518883,520364,1481.0,+,phosphomannomutase/phosphoglucomutase,0.5641,28,0.9843984831672717,2370.4315474667906,75.0,0.9844051770834826,2370.447666417026,73.0,nonessential
467,HNEAP_RS02460,WP_012823381.1,502585600.0,520364,521584,1220.0,+,hypothetical protein,0.4316,52,0.5136713677828484,1236.9206536210988,48.0,0.5408127479034892,1302.277096951602,47.0,nonessential
468,HNEAP_RS12140,WP_012823382.1,502585601.0,521678,524281,2603.0,+,group 1 glycosyl transferase,0.525,89,0.9850908117104498,2372.098674598763,125.0,0.9918695829417431,2388.4219557237175,124.0,nonessential
469,HNEAP_RS02470,WP_012823383.1,502585602.0,524409,525443,1034.0,+,GDP-mannose 4 6-dehydratase,0.5063,32,0.9982799423700537,2403.8581012270893,60.0,0.9978411691041199,2402.8015352027205,58.0,nonessential
470,HNEAP_RS02475,WP_012823384.1,502585603.0,525494,526405,911.0,+,GDP-6-deoxy-D-lyxo-4-hexulose reductase,0.5197,22,0.7731504846387924,1861.7463670102122,40.0,0.7284243682286426,1754.0458786945715,38.0,nonessential
471,HNEAP_RS02480,WP_012823385.1,502585604.0,526402,527598,1196.0,+,glycosyltransferase family 1 protein,0.4937,36,0.5110070402017937,1230.5049528059192,47.0,0.5366941195290216,1292.359439825884,46.0,nonessential
472,HNEAP_RS02485,WP_012823386.1,502585605.0,527608,528759,1151.0,+,group 1 glycosyl transferase,0.5469,34,0.9999157182484623,2407.797049542297,72.0,0.9999668198501798,2407.920102199233,72.0,nonessential
473,HNEAP_RS02490,WP_012823387.1,502585606.0,528849,530252,1403.0,+,undecaprenyl-phosphate glucose phosphotransferase,0.5285,34,0.9999998231057844,2407.999574038729,96.0,0.999999480682568,2407.9987494836237,92.0,nonessential
474,HNEAP_RS02495,WP_081441176.1,1174219995.0,530296,530964,668.0,-,nucleotidyltransferase family protein,0.5575,11,0.5890140299515516,1418.3457841233362,27.0,0.7194855735573056,1732.521261125992,28.0,nonessential
475,HNEAP_RS02500,WP_012823389.1,502585608.0,531017,532501,1484.0,-,TolC family type I secretion outer membrane protein,0.5495,27,0.6420297650757014,1546.007674302289,61.0,0.5813140547076001,1399.804243735901,58.0,nonessential
476,HNEAP_RS02505,WP_012823390.1,502585609.0,532762,533427,665.0,-,protein-L-isoaspartate O-methyltransferase,0.5465,10,8.168465393543358e-10,1.9669664667652406e-06,2.0,1.2705052863272414e-10,3.059376729475997e-07,1.0,essential
477,HNEAP_RS02510,WP_012823391.1,502585610.0,533871,535760,1889.0,+,phosphomethylpyrimidine synthase ThiC,0.563,36,7.286475421080251e-20,1.7545832813961247e-16,12.0,8.212723643469352e-20,1.9776238533474198e-16,11.0,essential
478,HNEAP_RS02515,WP_012823392.1,502585611.0,535846,536322,476.0,+,peroxiredoxin,0.5283,16,0.9945029671709965,2394.7631449477594,30.0,0.9964223317503036,2399.384974854731,30.0,nonessential
479,HNEAP_RS12145,WP_049772446.1,908628413.0,536333,537073,740.0,-,hypothetical protein,0.5776,23,0.4461711651775254,1074.3801657474812,28.0,0.43649990363185354,1051.0917679455033,27.0,nonessential
480,HNEAP_RS02525,WP_012823394.1,502585613.0,537148,538068,920.0,+,hypothetical protein,0.5603,14,0.3756889612978584,904.659018805243,34.0,0.44789008806229713,1078.5193320540116,34.0,nonessential
481,HNEAP_RS02530,WP_012823395.1,502585614.0,538079,538684,605.0,-,cation transporter,0.5479,11,0.9081294299821485,2186.7756673970134,30.0,0.9020109579566388,2172.042386759586,29.0,nonessential
482,HNEAP_RS02535,WP_012823396.1,502585615.0,538677,539000,323.0,-,DUF1244 domain-containing protein,0.5494,7,0.6958736030997016,1675.6636362640813,14.0,0.7344245161528273,1768.4942348960083,14.0,nonessential
483,HNEAP_RS02540,WP_012823397.1,502585616.0,539041,539262,221.0,-,BolA family transcriptional regulator,0.5495,2,0.4840546450311275,1165.603585234955,8.0,0.5207136499949234,1253.8784691877756,8.0,nonessential
484,HNEAP_RS02545,WP_012823398.1,502585617.0,539350,540474,1124.0,-,ribonuclease D,0.5742,18,0.971961005957454,2340.4821023455493,57.0,0.9832720446439781,2367.719083502699,57.0,nonessential
485,HNEAP_RS02550,WP_012823399.1,502585618.0,540479,541078,599.0,-,peptidyl-prolyl cis-trans isomerase,0.5333,15,0.40662172105192834,979.1451042930435,22.0,0.38153754515763716,918.7424087395902,21.0,nonessential
486,HNEAP_RS02555,WP_012823400.1,502585619.0,541071,541487,416.0,-,RNA polymerase-binding protein DksA,0.5492,6,0.8917787000440851,2147.403109706157,21.0,0.87178352545397,2099.25472929316,20.0,nonessential
487,HNEAP_RS12150,WP_012823401.1,502585620.0,541662,542414,752.0,-,energy transducer TonB,0.5657,11,0.9998060947817746,2407.5330762345134,50.0,0.9998251209716404,2407.57889129971,49.0,nonessential
488,HNEAP_RS02565,WP_081441087.1,1174219906.0,542470,543570,1100.0,-,FAD:protein FMN transferase,0.5777,19,2.3997364358781892e-11,5.7785653375946796e-08,8.0,3.666363917612786e-10,8.828604313611588e-07,9.0,essential
489,HNEAP_RS02570,WP_012823403.1,502585622.0,543609,544574,965.0,-,glutathione synthase,0.5776,13,1.237821450497027e-12,2.980674052796841e-09,4.0,3.6623676439375556e-13,8.818981286601634e-10,3.0,essential
490,HNEAP_RS02575,WP_012823404.1,502585623.0,544571,545920,1349.0,-,glutamate--cysteine ligase,0.5548,24,7.506813815491722e-11,1.8076407667704066e-07,14.0,2.5960609194794737e-10,6.251314694106573e-07,14.0,essential
491,HNEAP_RS02585,WP_012823405.1,502585624.0,546745,547107,362.0,+,response regulator,0.4876,6,0.999989254802423,2407.9741255642343,32.0,0.9999131355225419,2407.790830338281,29.0,nonessential
492,HNEAP_RS12155,WP_012823406.1,502585625.0,547127,547642,515.0,+,CheW protein,0.5446,8,0.9999945964161147,2407.986988170004,42.0,0.9999974467572836,2407.993851791539,42.0,nonessential
493,HNEAP_RS02595,WP_012823407.1,502585626.0,547722,549737,2015.0,+,methyl-accepting chemotaxis sensory transducer,0.5437,33,0.9359529320159339,2253.774660294369,93.0,0.9722501089390557,2341.178262325246,94.0,nonessential
494,HNEAP_RS02600,WP_012823408.1,502585627.0,549930,556457,6527.0,+,signal transduction histidine kinase,0.5363,88,0.2963199099072342,713.53834305662,250.0,0.2067657741727992,497.8919842081005,238.0,nonessential
495,HNEAP_RS02605,WP_012823409.1,502585628.0,556454,557026,572.0,+,hypothetical protein,0.5689,12,0.9229602425345581,2222.488264023216,29.0,0.9163907292485985,2206.668876030625,28.0,nonessential
496,HNEAP_RS02610,WP_012823410.1,502585629.0,557126,557770,644.0,-,hypothetical protein,0.5643,13,0.7902375325033351,1902.891978268031,29.0,0.7179076170465137,1728.721541848005,27.0,nonessential
497,HNEAP_RS02615,WP_012823411.1,502585630.0,557967,559820,1853.0,-,TonB-dependent receptor,0.5496,50,0.9999703860273514,2407.928689553862,109.0,0.9999472417943551,2407.8729582408073,105.0,nonessential
498,HNEAP_RS02620,WP_012823414.1,502585634.0,560457,561035,578.0,+,ADP compounds hydrolase NudE,0.5907,11,0.9965100689222789,2399.5962459648476,36.0,0.9978743695656307,2402.881481914039,36.0,nonessential
499,HNEAP_RS02625,WP_012823415.1,502585635.0,561069,561890,821.0,+,3'(2') 5'-bisphosphate nucleotidase,0.5973,15,0.9999753903313578,2407.94073991791,57.0,0.9999285684182395,2407.8279927511207,54.0,nonessential
500,HNEAP_RS02630,WP_012823416.1,502585636.0,561948,562556,608.0,+,type 1 glutamine amidotransferase,0.5665,2,5.292563977549742e-10,1.274449405793978e-06,1.0,1.0921936138957708e-09,2.6300022222610158e-06,1.0,essential
501,HNEAP_RS02635,WP_012823417.1,502585637.0,562553,563812,1259.0,+,MFS transporter,0.5857,21,0.8891198858787371,2141.000685195999,58.0,0.9046759283512176,2178.459635469732,57.0,nonessential
502,HNEAP_RS02640,WP_012823418.1,502585638.0,563956,564696,740.0,+,YebC/PmpR family DNA-binding transcriptional regulator,0.5533,15,0.9997579497757614,2407.4171430600336,49.0,0.9999366066521511,2407.84734881838,50.0,nonessential
503,HNEAP_RS02645,WP_041600606.1,753844989.0,564707,565264,557.0,+,crossover junction endodeoxyribonuclease RuvC,0.5914,6,0.9745133256615544,2346.628088193023,31.0,0.9350459031104166,2251.590534689883,28.0,nonessential
504,HNEAP_RS02650,WP_012823420.1,502585640.0,565261,565881,620.0,+,Holliday junction branch migration protein RuvA,0.5845,6,0.42176434125823653,1015.6085337498336,23.0,0.24617354778114414,592.785903056995,20.0,nonessential
505,HNEAP_RS02655,WP_012823421.1,502585641.0,565881,566927,1046.0,+,Holliday junction branch migration DNA helicase RuvB,0.5826,12,0.0034796762410119024,8.379060388356661,25.0,0.000530387889862244,1.2771740387882835,21.0,nonessential
506,HNEAP_RS02660,WP_012823422.1,502585642.0,566924,567334,410.0,+,tol-pal system-associated acyl-CoA thioesterase,0.5377,8,0.8569507659224282,2063.5374443412074,20.0,0.7636496875092793,1838.8684475223445,18.0,nonessential
507,HNEAP_RS02665,WP_012823423.1,502585643.0,567331,568008,677.0,+,protein TolQ,0.556,12,3.5899564563737986e-11,8.644615146948107e-08,1.0,8.070150261567408e-11,1.9432921829854318e-07,1.0,essential
508,HNEAP_RS02670,WP_012823424.1,502585644.0,568012,568467,455.0,+,protein TolR,0.5461,10,9.942800702246827e-09,2.394226409101036e-05,0.0,1.749403347324346e-08,4.212563260357025e-05,0.0,essential
509,HNEAP_RS02675,WP_012823425.1,502585645.0,568470,569507,1037.0,+,protein TolA,0.5684,7,8.878470916077357e-14,2.1379357965914275e-10,4.0,2.8430037184559326e-13,6.845952954041886e-10,4.0,essential
510,HNEAP_RS02680,WP_081441088.1,1174219907.0,569547,570884,1337.0,+,Tol-Pal system beta propeller repeat protein TolB,0.5336,33,1.718545565448131e-22,4.1382577215990995e-19,1.0,8.763079237458379e-22,2.1101494803799775e-18,1.0,essential
511,HNEAP_RS02685,WP_012823427.1,502585647.0,570959,571924,965.0,+,tol-pal system protein YbgF,0.5259,28,0.9999984055643453,2407.9961605989433,69.0,0.9999922106297529,2407.9812431964447,65.0,nonessential
512,HNEAP_RS02690,WP_012823428.1,502585648.0,571921,572604,683.0,+,7-carboxy-7-deazaguanine synthase QueE,0.5161,17,0.8076927793894471,1944.9242127697885,31.0,0.7441516937509267,1791.9172785522314,29.0,nonessential
513,HNEAP_RS02695,WP_012823429.1,502585649.0,572588,573295,707.0,+,7-cyano-7-deazaguanine synthase QueC,0.5169,27,0.9735153378374038,2344.2249335124684,38.0,0.9604841206840042,2312.845762607082,36.0,nonessential
514,HNEAP_RS02730,WP_012823430.1,502585650.0,579270,579479,209.0,+,hypothetical protein,0.5762,7,0.03219536067406446,77.52642850314723,3.0,0.03840528423436152,92.47992443634254,3.0,nonessential
515,HNEAP_RS02735,WP_041600339.1,753844722.0,579584,580069,485.0,+,hypothetical protein,0.5021,17,0.13230731962578704,318.5960256588952,14.0,0.16232303013952343,390.8738565759724,14.0,nonessential
516,HNEAP_RS02740,WP_012823432.1,502585652.0,580090,580716,626.0,-,cytochrome c,0.5104,21,0.25205429347660074,606.9467386916546,21.0,0.30268317322473787,728.8610811251688,21.0,nonessential
517,HNEAP_RS02745,WP_012823433.1,502585653.0,580753,581355,602.0,-,purine or other phosphorylase family 1,0.5124,16,0.9998016247881165,2407.522312489785,42.0,0.9996098214546152,2407.0604500627132,40.0,nonessential
518,HNEAP_RS02750,WP_012823434.1,502585654.0,581371,581889,518.0,-,adenine phosphoribosyltransferase,0.5491,11,0.9358550749414277,2253.539020458958,27.0,0.8509261590821796,2049.0301910698886,24.0,nonessential
519,HNEAP_RS02755,WP_012823435.1,502585655.0,582064,582624,560.0,-,Smr protein/MutS2,0.5472,8,0.365270434795003,879.5712069863672,20.0,0.4208136812897085,1013.319344545618,20.0,nonessential
520,HNEAP_RS02760,WP_012823436.1,502585656.0,582732,583496,764.0,+,5'/3'-nucleotidase SurE,0.5791,12,0.8724482487312734,2100.855382944906,36.0,0.44320592406372,1067.2398651454378,28.0,nonessential
521,HNEAP_RS02765,WP_041600612.1,753844995.0,583658,584272,614.0,+,protein-L-isoaspartate(D-aspartate) O-methyltransferase,0.5561,16,0.9946320468236641,2395.0739687513833,37.0,0.9966979913050409,2400.0487630625385,37.0,nonessential
522,HNEAP_RS02770,WP_012823438.1,502585658.0,584269,584856,587.0,+,DedA family protein,0.5425,12,0.006934057086643277,16.697209464637012,12.0,0.010074102523069412,24.258438875551146,12.0,nonessential
523,HNEAP_RS02775,WP_049772449.1,908628416.0,584866,585666,800.0,+,hypothetical protein,0.5743,15,0.09059373999629,218.14972591106633,24.0,0.008095427537457348,19.493789510197296,18.0,nonessential
524,HNEAP_RS02780,WP_081441089.1,1174219908.0,585700,586635,935.0,-,WYL domain-containing protein,0.5214,23,1.926579353847474e-10,4.639203084064718e-07,6.0,5.113027014735612e-10,1.2312169051483354e-06,6.0,essential
525,HNEAP_RS02785,WP_012823441.1,502585661.0,586732,587064,332.0,+,hypothetical protein,0.5045,8,0.14920416145619653,359.2836207865212,9.0,0.17558991839403765,422.82052349284265,9.0,nonessential
526,HNEAP_RS02790,WP_081441090.1,1174219909.0,587087,588085,998.0,-,zinc transporter ZntB,0.5245,22,0.78888000626766,1899.6230550925252,44.0,0.9054084466885548,2180.22353962604,46.0,nonessential
527,HNEAP_RS02795,WP_012823443.1,502585663.0,588122,588712,590.0,-,class I SAM-dependent methyltransferase,0.533,10,0.9984063354642584,2404.1624557979344,38.0,0.9990733814133423,2405.7687024433285,38.0,nonessential
528,HNEAP_RS02800,WP_012823444.1,502585664.0,588783,589244,461.0,-,Fur family transcriptional regulator,0.539,8,0.9889980843701409,2381.5073871632994,28.0,0.9869620280153665,2376.6045634610023,27.0,nonessential
529,HNEAP_RS02805,WP_012823445.1,502585665.0,589563,590513,950.0,+,MBL fold metallo-hydrolase,0.5205,20,0.2464802369366504,593.5244105434541,33.0,0.19807367845314697,476.9614177151779,31.0,nonessential
530,HNEAP_RS02810,WP_012823446.1,502585666.0,590651,591175,524.0,+,hypothetical protein,0.5981,10,0.9691351504720538,2333.6774423367056,29.0,0.9782305445358316,2355.5791512422825,29.0,nonessential
531,HNEAP_RS02815,WP_012823447.1,502585667.0,591175,591831,656.0,+,hypothetical protein,0.5358,19,0.999368255246479,2406.4787586335215,43.0,0.9906846422576251,2385.5686185563613,37.0,nonessential
532,HNEAP_RS02825,WP_012823449.1,502585669.0,592488,593195,707.0,+,hypothetical protein,0.5113,15,0.8523677962626262,2052.501653400404,33.0,0.8490551877885593,2044.5248921948507,32.0,nonessential
533,HNEAP_RS02830,WP_012823450.1,502585670.0,593331,594320,989.0,+,sulfurtransferase,0.497,28,0.00540148422559083,13.006774015222717,24.0,0.0052531188888022325,12.649510284235776,23.0,nonessential
534,HNEAP_RS02835,WP_012823451.1,502585671.0,594473,595366,893.0,-,phosphoribulokinase,0.5201,21,7.459797038138358e-15,1.7963191267837168e-11,1.0,2.1922713719523837e-14,5.27898946366134e-11,1.0,essential
535,HNEAP_RS02850,WP_012823452.1,502585672.0,596841,597224,383.0,+,peptidoglycan-associated lipoprotein,0.5312,14,0.01453861837714161,35.008993052156995,7.0,0.019101587169478053,45.99662190410315,7.0,nonessential
536,HNEAP_RS02855,WP_012823453.1,502585673.0,597323,600874,3551.0,-,exodeoxyribonuclease V subunit gamma,0.5611,60,0.9999999999944492,2407.9999999866336,226.0,0.9999999999421376,2407.9999998606672,216.0,nonessential
537,HNEAP_RS02860,WP_012823454.1,502585674.0,600968,601996,1028.0,-,GGDEF domain-containing protein,0.5462,25,0.9653097530074795,2324.4658852420107,52.0,0.9423341387298705,2269.140606061528,49.0,nonessential
538,HNEAP_RS02865,WP_012823455.1,502585675.0,602125,602694,569.0,-,elongation factor P,0.5175,8,2.4095748291726248e-09,5.802256188647681e-06,1.0,4.737797420472084e-09,1.1408616188496777e-05,1.0,essential
539,HNEAP_RS02870,WP_012823456.1,502585676.0,602767,603915,1148.0,-,elongation factor P maturation arginine rhamnosyltransferase EarP,0.5753,13,0.9711854245791363,2338.61450238656,58.0,0.645991625262774,1555.5478336327596,46.0,nonessential
540,HNEAP_RS02875,WP_012823457.1,502585677.0,603916,605412,1496.0,-,hypothetical protein,0.5531,31,0.9999999994342447,2407.999998637661,110.0,0.9999999968500047,2407.9999924148115,105.0,nonessential
541,HNEAP_RS02880,WP_012823458.1,502585678.0,605669,607567,1898.0,+,ABC transporter ATP-binding protein,0.5793,28,0.999979265507339,2407.9500713416724,112.0,0.99997696595436,2407.944534018099,109.0,nonessential
542,HNEAP_RS02885,WP_012823459.1,502585679.0,607592,607960,368.0,+,hypothetical protein,0.542,6,0.9999999869271717,2407.9999685206294,39.0,0.9999999942912661,2407.9999862533687,39.0,nonessential
543,HNEAP_RS02890,WP_012823460.1,502585680.0,608062,608937,875.0,+,RNA polymerase sigma factor RpoH,0.5582,10,1.516007324761285e-14,3.650545638025174e-11,1.0,4.3568098733169186e-14,1.049119817494714e-10,1.0,essential
544,HNEAP_RS02895,WP_041600623.1,753845006.0,608986,609618,632.0,-,MarC family protein,0.564,8,0.8177411914583086,1969.120789031607,29.0,0.8569017451616476,2063.4194023492473,29.0,nonessential
545,HNEAP_RS02900,WP_012823462.1,502585682.0,609765,610328,563.0,+,phosphatidylethanolamine N-methyltransferase,0.5567,10,0.20606529010165633,496.2052185647885,18.0,0.24903147365658457,599.6677885650556,18.0,nonessential
546,HNEAP_RS02905,WP_012823463.1,502585683.0,610397,610816,419.0,-,biopolymer transporter ExbD,0.4548,19,0.14949350466132322,359.9803592244663,12.0,0.1159429348403104,279.19058709546744,11.0,nonessential
547,HNEAP_RS02910,WP_012823464.1,502585684.0,610822,611535,713.0,-,MotA/TolQ/ExbB proton channel family protein,0.514,20,0.9981533928872748,2403.5533700725578,44.0,0.9969888084678151,2400.749050790499,42.0,nonessential
548,HNEAP_RS12465,WP_081441091.1,1174219910.0,611555,612193,638.0,-,energy transducer TonB,0.5524,10,0.946573524331905,2279.3490465912273,33.0,0.9440063456059452,2273.167280219116,32.0,nonessential
549,HNEAP_RS02920,WP_012823466.1,502585687.0,612638,614902,2264.0,+,catecholate siderophore receptor Fiu,0.5263,80,0.984761158660153,2371.3048700536483,110.0,0.984731708180289,2371.233953298136,107.0,nonessential
550,HNEAP_RS02925,WP_012823467.1,502585688.0,614994,615671,677.0,+,Fe2+-dependent dioxygenase,0.5383,14,0.7672413561183227,1847.517185532921,30.0,0.6238034532678476,1502.118715468977,27.0,nonessential
551,HNEAP_RS12165,WP_081441092.1,1174219911.0,615656,618205,2549.0,+,hypothetical protein,0.5643,53,0.9936471018371613,2392.7022212238844,126.0,0.9942946766737547,2394.2615814304013,123.0,nonessential
552,HNEAP_RS02935,WP_012823469.1,502585690.0,618276,620030,1754.0,-,glucan biosynthesis protein D,0.5726,34,0.7670139613576038,1846.9696189491099,75.0,0.6943579823008252,1672.0140213803872,71.0,nonessential
553,HNEAP_RS02940,WP_012823470.1,502585691.0,620062,622176,2114.0,-,glucans biosynthesis glucosyltransferase MdoH,0.5745,34,0.9991862193043174,2406.040416084796,113.0,0.9994149707815334,2406.5912496419323,111.0,nonessential
554,HNEAP_RS02945,WP_012823471.1,502585692.0,622173,622466,293.0,-,hypothetical protein,0.5748,4,0.9927863806616998,2390.629604633373,20.0,0.9948198238202448,2395.5261357591494,20.0,nonessential
555,HNEAP_RS02950,WP_012823472.1,502585693.0,622463,624070,1607.0,-,glucan biosynthesis protein G,0.5541,31,0.999999997810027,2407.999994726545,114.0,0.9999999811335063,2407.999954569483,108.0,nonessential
556,HNEAP_RS02955,WP_012823473.1,502585694.0,624563,628069,3506.0,+,DNA polymerase III subunit alpha,0.578,62,2.171938491423741e-62,5.2300278873483685e-59,0.0,1.6890058572888242e-60,4.067126104351489e-57,0.0,essential
557,HNEAP_RS02960,WP_012823474.1,502585695.0,628185,628421,236.0,+,DUF465 domain-containing protein,0.3966,6,0.04087669363130401,98.43107826418004,4.0,0.04902048264918845,118.04132221924579,4.0,nonessential
558,HNEAP_RS02965,WP_012823475.1,502585696.0,628854,629573,719.0,-,hypothetical protein,0.5167,23,4.4329109127574365e-06,0.010674449477919908,8.0,8.48716801936576e-06,0.02043710059063275,8.0,essential
559,HNEAP_RS02970,WP_012823476.1,502585697.0,629551,630921,1370.0,-,sulfite dehydrogenase,0.5208,26,0.06236186128423088,150.16736197242795,43.0,0.003411123208506304,8.21398468608318,34.0,nonessential
560,HNEAP_RS02975,WP_012823477.1,502585698.0,631283,631774,491.0,+,molybdenum cofactor biosynthesis protein MoaE,0.5833,4,0.1794345474446059,432.07839024661104,15.0,0.03374342136098329,81.25415863724776,11.0,nonessential
561,HNEAP_RS02980,WP_081441093.1,1174219912.0,631803,633038,1235.0,+,molybdopterin molybdenumtransferase MoeA,0.585,21,0.9990163765830813,2405.6314348120595,71.0,0.9049015122084778,2179.0028413980144,56.0,nonessential
562,HNEAP_RS02985,WP_041600342.1,753844725.0,633026,633514,488.0,+,cyclic pyranopterin monophosphate synthase MoaC,0.5746,9,0.9649099309365406,2323.5031136951898,27.0,0.745445213757904,1795.0320747290327,21.0,nonessential
563,HNEAP_RS02990,WP_012823480.1,502585701.0,634043,635029,986.0,+,GTP 3' 8-cyclase MoaA,0.5613,17,0.40405190330447854,972.9569831571844,37.0,0.036678198314719405,88.32110154184433,27.0,nonessential
564,HNEAP_RS02995,WP_012823481.1,502585702.0,635192,636610,1418.0,-,protoporphyrinogen oxidase,0.5666,25,2.0404170568980278e-22,4.913324273010451e-19,2.0,1.1151428976769047e-21,2.6852640976059864e-18,2.0,essential
565,HNEAP_RS03000,WP_012823482.1,502585703.0,636735,637685,950.0,+,complex I NDUFA9 subunit family protein,0.5563,21,0.9983573183639933,2404.044422620496,56.0,0.9986366132604197,2404.7169647310907,55.0,nonessential
566,HNEAP_RS03005,WP_012823483.1,502585704.0,637943,638485,542.0,+,membrane protein,0.5138,11,0.42468124896306164,1022.6324475030524,20.0,0.4812803948286517,1158.9231907473934,20.0,nonessential
567,HNEAP_RS03010,WP_012823484.1,502585705.0,638544,639821,1277.0,+,membrane protein,0.5618,30,0.9174687720448281,2209.264803083946,60.0,0.9469083090703395,2280.1552082413777,60.0,nonessential
568,HNEAP_RS03015,WP_012823485.1,502585706.0,639959,641236,1277.0,-,pyridine nucleotide-disulfide oxidoreductase,0.5274,32,0.9512928957387181,2290.713292938833,62.0,0.8857620526088995,2132.91502268223,57.0,nonessential
569,HNEAP_RS03020,WP_041600343.1,753844726.0,641228,641461,233.0,+,hypothetical protein,0.4829,5,0.17968137251378277,432.6727450131889,6.0,0.2042317373789271,491.79002360845647,6.0,nonessential
570,HNEAP_RS03025,WP_012823486.1,502585707.0,641526,642506,980.0,-,50S ribosomal protein L3 N(5)-glutamine methyltransferase,0.5596,24,0.9999999900286795,2407.99997598906,77.0,0.9999998813969861,2407.9997144039426,72.0,nonessential
571,HNEAP_RS03030,WP_012823487.1,502585708.0,642601,643512,911.0,+,phosphatidylserine decarboxylase,0.5735,18,3.669318634328183e-15,8.835719271462265e-12,1.0,1.1026889041780109e-14,2.6552748812606502e-11,1.0,essential
572,HNEAP_RS03035,WP_012823488.1,502585709.0,643647,645275,1628.0,+,hypothetical protein,0.5285,36,0.9459382760828307,2277.819368807456,77.0,0.9475967668125822,2281.8130144846978,75.0,nonessential
573,HNEAP_RS03040,WP_012823489.1,502585710.0,645268,647349,2081.0,+,diguanylate cyclase,0.5264,40,0.7830888185612992,1885.6778750956084,89.0,0.8572662035321487,2064.297018105414,89.0,nonessential
574,HNEAP_RS03045,WP_012823490.1,502585711.0,647365,647769,404.0,+,dihydroneopterin aldolase,0.5383,9,7.269021476472018e-05,0.17503803715344618,3.0,1.9126611838589043e-05,0.04605688130732241,2.0,ambiguous
575,HNEAP_RS03050,WP_012823491.1,502585712.0,647796,648992,1196.0,+,SAM-dependent methyltransferase,0.5906,20,4.651177234481655e-20,1.1200034780631825e-16,1.0,4.0726975807171305e-21,9.80705577436685e-18,0.0,essential
576,HNEAP_RS03055,WP_012823493.1,502585714.0,649140,649949,809.0,+,TatD family deoxyribonuclease,0.5765,16,0.3271410070305842,787.7555449296467,29.0,0.3919333954481035,943.7756162390333,29.0,nonessential
577,HNEAP_RS03060,WP_012823494.1,502585715.0,649968,650939,971.0,+,thiamine-phosphate kinase,0.5916,18,8.359032278101218e-18,2.0128549725667733e-14,0.0,2.7913590453502626e-17,6.721592581203433e-14,0.0,essential
578,HNEAP_RS03065,WP_012823495.1,502585716.0,650943,651485,542.0,+,phosphatidylglycerophosphatase A,0.5672,5,0.05479127106923606,131.93738073472042,14.0,0.11184686320292421,269.3272465926415,15.0,nonessential
579,HNEAP_RS03070,WP_012823496.1,502585717.0,651557,652030,473.0,+,hypothetical protein,0.5612,6,0.938149651598889,2259.0643610501247,25.0,0.9536329511019701,2296.348146253544,25.0,nonessential
580,HNEAP_RS03075,WP_012823497.1,502585718.0,652259,652585,326.0,-,hypothetical protein,0.4862,9,0.9985113145508194,2404.4152454383734,24.0,0.9978978526511291,2402.938029183919,23.0,nonessential
581,HNEAP_RS03080,WP_041600636.1,753845019.0,652749,654206,1457.0,+,IMP dehydrogenase,0.5761,27,2.3683182243925897e-26,5.702910284337356e-23,0.0,1.446103098446272e-25,3.482216261058623e-22,0.0,essential
582,HNEAP_RS03085,WP_012823499.1,502585720.0,654431,656017,1586.0,+,glutamine-hydrolyzing GMP synthase,0.5841,21,1.2752692090170602e-28,3.070848255313081e-25,0.0,9.139673760375722e-28,2.2008334414984737e-24,0.0,essential
583,HNEAP_RS12470,WP_012823500.1,502585721.0,656235,656378,143.0,-,DUF3096 domain-containing protein,0.4375,8,0.6593542960773251,1587.7251449541989,6.0,0.6868416309903005,1653.9146474246436,6.0,nonessential
584,HNEAP_RS03090,WP_012823501.1,502585722.0,656645,657106,461.0,+,nucleoside deaminase,0.5931,6,1.5636943899953042e-07,0.00037653760911086925,1.0,1.3822875362681028e-08,3.3285483873335914e-05,0.0,essential
585,HNEAP_RS03095,WP_012823502.1,502585723.0,657394,658848,1454.0,+,type I restriction-modification protein subunit M,0.5533,27,0.9999999999730907,2407.9999999352026,112.0,0.9999999999592788,2407.9999999019433,109.0,nonessential
586,HNEAP_RS12170,WP_012823503.1,502585724.0,658845,660050,1205.0,+,restriction modification system DNA specificity domain-containing protein,0.495,34,0.10714753626157247,258.0112673178665,39.0,0.022596214232926685,54.41168387288746,33.0,nonessential
587,HNEAP_RS03110,WP_012823504.1,502585725.0,660063,661481,1418.0,+,hypothetical protein,0.5215,38,0.9998420011268061,2407.619538713349,84.0,0.999758221389861,2407.417797106785,81.0,nonessential
588,HNEAP_RS03115,WP_012823505.1,502585726.0,661782,664133,2351.0,+,restriction endonuclease subunit R,0.5574,43,0.8994385582033106,2165.848048153572,105.0,0.8329843782980414,2005.8263829416837,99.0,nonessential
589,HNEAP_RS12475,WP_012823506.1,502585727.0,664629,664817,188.0,-,CPXCG motif-containing cysteine-rich protein,0.5661,4,0.37935725006408283,913.4922581543115,6.0,0.41151460267309425,990.927163236811,6.0,nonessential
590,HNEAP_RS03130,WP_012823507.1,502585728.0,664969,666234,1265.0,-,isocitrate dehydrogenase (NADP(+)),0.5735,23,3.005298593479838e-21,7.23675901309945e-18,1.0,2.7134961546625204e-22,6.534098740427349e-19,0.0,essential
591,HNEAP_RS03135,WP_012823508.1,502585729.0,666614,666904,290.0,+,co-chaperone GroES,0.5464,4,7.934344652091198e-06,0.019105901922235605,0.0,1.1373860104542275e-05,0.027388255131737798,0.0,essential
592,HNEAP_RS03140,WP_012823509.1,502585730.0,666956,668590,1634.0,+,chaperonin GroEL,0.5511,25,1.8255049508341006e-29,4.3958159216085145e-26,0.0,1.388667288807024e-28,3.343910831447314e-25,0.0,essential
593,HNEAP_RS03145,WP_012823510.1,502585731.0,668711,671287,2576.0,-,DUF3417 domain-containing protein,0.5452,53,0.9999172081480913,2407.8006372206037,141.0,0.9998628718692623,2407.6697954611836,136.0,nonessential
594,HNEAP_RS03150,WP_012823511.1,502585732.0,671632,672495,863.0,+,flagellin,0.5162,24,0.9994896659933076,2406.7711157118847,54.0,0.9987586470427527,2405.0108220789484,51.0,nonessential
595,HNEAP_RS03155,WP_012823512.1,502585733.0,672599,673006,407.0,+,flagellar protein FlaG,0.5074,8,0.8055627449297704,1939.7950897908872,19.0,0.8903393096166574,2143.937057556911,20.0,nonessential
596,HNEAP_RS03160,WP_012823513.1,502585734.0,673053,674459,1406.0,+,flagellar hook-associated 2 domain-containing protein,0.4989,48,0.7843040653766044,1888.6041894268633,61.0,0.9009128875842645,2169.398233302909,63.0,nonessential
597,HNEAP_RS03165,WP_081441094.1,1174219913.0,674545,674991,446.0,+,flagellar export chaperone FliS,0.5459,8,0.3061950102514416,737.3175846854713,15.0,0.3525072073692609,848.8373553451802,15.0,nonessential
598,HNEAP_RS03170,WP_012823515.1,502585736.0,675015,675380,365.0,+,hypothetical protein,0.582,5,0.9999260782002635,2407.8219963062343,30.0,0.9999826181271243,2407.9581444501155,31.0,nonessential
599,HNEAP_RS03175,WP_012823516.1,502585737.0,675468,678083,2615.0,-,hypothetical protein,0.5428,45,0.999999994678421,2407.999987185638,165.0,0.9999999908678062,2407.9999780096773,160.0,nonessential
600,HNEAP_RS03180,WP_012823517.1,502585738.0,678371,679375,1004.0,+,NAD-dependent dehydratase,0.5562,24,0.9921660655553127,2389.135885857193,55.0,0.995650404533819,2397.5261741174363,55.0,nonessential
601,HNEAP_RS03185,WP_012823518.1,502585739.0,679368,680522,1154.0,+,aminotransferase DegT,0.5983,18,0.8758160418504075,2108.9650287757813,53.0,0.9146060277354711,2202.3713147870144,53.0,nonessential
602,HNEAP_RS03190,WP_012823519.1,502585740.0,680522,681700,1178.0,+,UDP-N-acetylglucosamine 2-epimerase (hydrolyzing),0.609,12,0.17597392661586705,423.74521529100787,40.0,0.11510180612189379,277.16514914152026,37.0,nonessential
603,HNEAP_RS03195,WP_012823520.1,502585741.0,681767,682846,1079.0,+,N-acetylneuraminate synthase,0.6019,10,0.5513542116687583,1327.66094169837,43.0,0.38201854102294047,919.9006467832406,39.0,nonessential
604,HNEAP_RS03200,WP_012823521.1,502585743.0,682839,683474,635.0,+,sugar O-acyltransferase  sialic acid O-acetyltransferase NeuD family,0.6053,13,0.2990460291705632,720.1028382427162,22.0,0.4348942160856121,1047.225272334154,23.0,nonessential
605,HNEAP_RS03205,WP_012823522.1,502585744.0,683486,684547,1061.0,+,alcohol dehydrogenase,0.5847,21,0.11332433614404544,272.8850014348614,34.0,0.11842932990651585,285.17782641489015,33.0,nonessential
606,HNEAP_RS03210,WP_012823523.1,502585745.0,684540,685226,686.0,+,acylneuraminate cytidylyltransferase family protein,0.6114,10,0.17856756472903815,429.99069586752387,22.0,0.1651210834703728,397.6115689966577,21.0,nonessential
607,HNEAP_RS03215,WP_012823524.1,502585746.0,685312,687018,1706.0,-,proline--tRNA ligase,0.5934,24,9.886776734179858e-31,2.38073583759051e-27,0.0,8.224310017004982e-30,1.9804138520947996e-26,0.0,essential
608,HNEAP_RS03220,WP_012823525.1,502585747.0,687242,687709,467.0,-,DUF4124 domain-containing protein,0.5085,10,0.3250157358545597,782.6378919377797,16.0,0.37360411090875506,899.6386990682822,16.0,nonessential
609,HNEAP_RS03225,WP_012823526.1,502585748.0,687958,688896,938.0,+,LysR family transcriptional regulator,0.5016,24,0.76645612867542,1845.6263578504113,41.0,0.17100391108686505,411.77741789717106,30.0,nonessential
610,HNEAP_RS03230,WP_012823527.1,502585749.0,689375,689944,569.0,-,DUF302 domain-containing protein,0.5105,17,0.05774468985765277,139.04921317722787,15.0,0.02678771312312112,64.50481320047565,13.0,nonessential
611,HNEAP_RS03235,WP_012823528.1,502585750.0,690099,690722,623.0,+,amino acid-binding ACT domain-containing protein,0.5192,18,0.9976471303654856,2402.3342899200893,39.0,0.9975695790324897,2402.147546310235,38.0,nonessential
612,HNEAP_RS03240,WP_012823529.1,502585751.0,690756,691232,476.0,+,peroxiredoxin,0.5262,11,0.2958524457171942,712.4126892870037,16.0,0.25705322745323694,618.9841717073946,15.0,nonessential
613,HNEAP_RS03245,WP_012823530.1,502585752.0,691279,692709,1430.0,+,phosphate starvation protein PhoH,0.5632,21,0.044434299434894915,106.99779303922696,44.0,0.01908809935642262,45.96414325026567,40.0,nonessential
614,HNEAP_RS03250,WP_012823531.1,502585753.0,692802,695087,2285.0,-,5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase,0.5927,32,6.185555365125144e-39,1.4894817319221346e-35,1.0,1.0233588482552792e-37,2.4642481065987124e-34,1.0,essential
615,HNEAP_RS03255,WP_012823532.1,502585754.0,695263,695613,350.0,+,hypothetical protein,0.547,6,0.582239517433349,1402.0327579795044,14.0,0.5201409194717197,1252.499334087901,13.0,nonessential
616,HNEAP_RS03260,WP_012823533.1,502585755.0,695700,696620,920.0,-,alpha/beta hydrolase,0.5451,20,0.8440962844024993,2032.5838528412182,42.0,0.8856404879009666,2132.6222948655277,42.0,nonessential
617,HNEAP_RS03265,WP_012823534.1,502585756.0,696750,697475,725.0,-,ribonuclease T,0.5771,8,0.9999999897640236,2407.9999753517686,62.0,0.9999999986369779,2407.999996717843,63.0,nonessential
618,HNEAP_RS03270,WP_012823535.1,502585757.0,697487,698347,860.0,-,bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD,0.5993,10,2.736616077511438e-14,6.589771514647543e-11,1.0,7.719658445859202e-14,1.8588937537628958e-10,1.0,essential
619,HNEAP_RS03275,WP_012823536.1,502585758.0,698414,699451,1037.0,-,TIGR00341 family protein,0.579,8,0.9999690175016408,2407.925394143951,68.0,0.9999781346969374,2407.947348350225,67.0,nonessential
620,HNEAP_RS03280,WP_049772456.1,908628423.0,699454,701469,2015.0,-,ATP-dependent DNA helicase,0.5878,20,0.9997848864108816,2407.482006477403,112.0,0.9998460822636998,2407.629366090989,110.0,nonessential
621,HNEAP_RS12175,WP_081441095.1,1174219914.0,701519,702229,710.0,-,hypothetical protein,0.5809,7,0.8468296121037906,2039.1657059459278,33.0,0.8435248256297817,2031.2077801165144,32.0,nonessential
622,HNEAP_RS03290,WP_012823539.1,502585761.0,702343,704835,2492.0,-,penicillin-binding protein 1B,0.5628,51,0.9999977124113968,2407.9944914866433,146.0,0.9999936338081993,2407.984670210144,140.0,nonessential
623,HNEAP_RS03295,WP_081441096.1,1174219915.0,704979,706514,1535.0,+,hypothetical protein,0.556,26,0.03576576215459381,86.1239552682619,47.0,0.0004026840078971783,0.9696630910164054,35.0,nonessential
624,HNEAP_RS03300,WP_012823541.1,502585763.0,706695,706901,206.0,-,glycine zipper 2TM domain-containing protein,0.6135,3,0.42544126581834574,1024.4625680905765,7.0,0.602524253893497,1450.8784033755408,8.0,nonessential
625,HNEAP_RS03305,WP_012823542.1,502585764.0,707090,709735,2645.0,-,DNA mismatch repair protein MutS,0.6028,32,0.9982962545569933,2403.89738097324,135.0,0.9980701121791224,2403.352830127327,131.0,nonessential
626,HNEAP_RS03310,WP_012823543.1,502585765.0,710076,710870,794.0,-,septum site-determining protein MinC,0.5535,17,0.36641232891914965,882.3208880373123,29.0,0.4329219180356767,1042.4759786299096,29.0,nonessential
627,HNEAP_RS03315,WP_012823544.1,502585766.0,710959,711789,830.0,-,cell division protein ZapD,0.5259,9,0.9510440906075981,2290.114170183096,42.0,0.9344104305300185,2250.0603167162844,40.0,nonessential
628,HNEAP_RS03320,WP_012823545.1,502585768.0,711964,715680,3716.0,-,methionine synthase,0.5784,57,0.9999589624307131,2407.9011815331573,196.0,0.9998977708985975,2407.7538323238227,188.0,nonessential
629,HNEAP_RS03325,WP_012823546.1,502585769.0,715754,716293,539.0,-,DUF2062 domain-containing protein,0.5185,17,0.9964793928969558,2399.5223780958695,34.0,0.9993738630136021,2406.4922621367537,36.0,nonessential
630,HNEAP_RS03330,WP_012823547.1,502585770.0,716377,717930,1553.0,-,MFS transporter,0.5386,25,0.8980932775143364,2162.608612254522,71.0,0.8737381743916519,2103.961523935098,68.0,nonessential
631,HNEAP_RS03335,WP_012823548.1,502585771.0,717952,719160,1208.0,-,HlyD family secretion protein,0.5393,29,0.9999838891153306,2407.9612049897164,78.0,0.9999943591144288,2407.9864167475444,78.0,nonessential
632,HNEAP_RS03340,WP_012823549.1,502585772.0,719129,719608,479.0,-,MarR family transcriptional regulator,0.5167,6,2.9420925173106622e-05,0.07084558781684075,4.0,0.00019165266030277025,0.46149960600907075,5.0,nonessential
633,HNEAP_RS03345,WP_012823550.1,502585773.0,720189,721838,1649.0,+,CTP synthase,0.5442,35,2.3766738579470138e-26,5.723030649936409e-23,2.0,1.7301841278196648e-25,4.166283379789753e-22,2.0,essential
634,HNEAP_RS03350,WP_012823551.1,502585774.0,721835,722677,842.0,+,3-deoxy-8-phosphooctulonate synthase,0.5753,9,1.5523662253064077e-15,3.7380978705378295e-12,0.0,4.416561323947195e-15,1.0635079668064846e-11,0.0,essential
635,HNEAP_RS03355,WP_012823552.1,502585775.0,722758,724038,1280.0,+,phosphopyruvate hydratase,0.5535,30,3.072536839424766e-23,7.398668709334837e-20,0.0,1.5059144751169504e-22,3.6262420560816167e-19,0.0,essential
636,HNEAP_RS03360,WP_012823553.1,502585776.0,724065,724481,416.0,+,septum formation initiator,0.5468,5,0.031050518917861505,74.7696495542105,9.0,0.008907332094689819,21.448855684013083,7.0,nonessential
637,HNEAP_RS03365,WP_081441177.1,1174219996.0,724547,725305,758.0,+,2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase,0.5705,9,1.5064197665554376e-12,3.6274587978654938e-09,1.0,3.744308783057967e-12,9.016295549603584e-09,1.0,essential
638,HNEAP_RS03370,WP_012823555.1,502585778.0,725322,725843,521.0,+,2-C-methyl-D-erythritol 2 4-cyclodiphosphate synthase,0.59,7,1.7433469928223193e-07,0.0004197979558716145,2.0,3.133750886772659e-07,0.0007546072135348563,2.0,essential
639,HNEAP_RS03375,WP_081441097.1,1174219916.0,726015,726611,596.0,-,GGDEF domain-containing protein,0.5494,13,0.060533826357893256,145.76545386980695,16.0,0.07968171898993098,191.87357932775382,16.0,nonessential
640,HNEAP_RS03380,WP_041600348.1,753844731.0,726604,728736,2132.0,-,hypothetical protein,0.519,54,0.8102568675879257,1951.0985371517252,92.0,0.7329905978866273,1765.0413597109987,87.0,nonessential
641,HNEAP_RS03385,WP_081441098.1,1174219917.0,728934,731243,2309.0,-,protein-disulfide reductase DsbD,0.5571,42,1.1397157753566605e-37,2.7444355870588383e-34,2.0,1.8825186679342358e-36,4.5331049523856396e-33,2.0,essential
642,HNEAP_RS03390,WP_049772460.1,908628427.0,731472,731933,461.0,+,hypothetical protein,0.526,11,0.34530707350973633,831.499433011445,16.0,0.3946546804117416,950.3284704314739,16.0,nonessential
643,HNEAP_RS03395,WP_012823558.1,502585781.0,732262,732765,503.0,+,pyridoxamine 5'-phosphate oxidase-like FMN-binding protein,0.5377,10,0.8939458496522671,2152.621605962659,25.0,0.8808386801764213,2121.0595418648227,24.0,nonessential
644,HNEAP_RS03400,WP_012823559.1,502585782.0,732823,733632,809.0,-,cytochrome c assembly protein,0.5222,23,0.9994135128436531,2406.5877389275165,51.0,0.9997049416331684,2407.2894994526696,51.0,nonessential
645,HNEAP_RS03405,WP_012823560.1,502585783.0,733707,735158,1451.0,-,dimethylmenaquinone methyltransferase,0.5964,12,0.9421361930815433,2268.663952940356,69.0,0.9406511953777528,2265.0880784696287,67.0,nonessential
646,HNEAP_RS03410,WP_012823561.1,502585784.0,735155,735709,554.0,-,SIS domain-containing protein,0.5946,5,0.9946390281461375,2395.090779775899,34.0,0.9966252009883402,2399.873483979923,34.0,nonessential
647,HNEAP_RS03415,WP_049772461.1,908628428.0,735787,736212,425.0,-,YraN family protein,0.5775,3,0.9653105880870544,2324.467896113627,24.0,0.9745264223319,2346.659624975215,24.0,nonessential
648,HNEAP_RS03420,WP_081441099.1,1174219918.0,736259,738523,2264.0,-,hypothetical protein,0.5841,41,0.9999999999999699,2407.9999999999277,167.0,0.9999999999999977,2407.9999999999945,167.0,nonessential
649,HNEAP_RS03425,WP_081441178.1,1174219997.0,738488,739456,968.0,+,16S rRNA (cytidine(1402)-2'-O)-methyltransferase,0.613,12,0.9999999999999948,2407.9999999999873,93.0,0.9999999999999991,2407.9999999999977,93.0,nonessential
650,HNEAP_RS03430,WP_012823565.1,502585788.0,739553,740455,902.0,+,4-hydroxy-tetrahydrodipicolinate synthase,0.6024,14,1.0010195394728862e-13,2.41045505105071e-10,2.0,1.554870159210797e-14,3.7441273433795996e-11,1.0,essential
651,HNEAP_RS03435,WP_012823566.1,502585789.0,740592,741719,1127.0,+,outer membrane protein assembly factor BamC,0.5337,29,0.9707104675856518,2337.4708059462496,57.0,0.9658806952524277,2325.840714167846,55.0,nonessential
652,HNEAP_RS03440,WP_012823567.1,502585790.0,741930,743156,1226.0,+,argininosuccinate synthase,0.5542,23,2.736801598803586e-22,6.590218249919035e-19,0.0,1.2543662412734258e-21,3.0205139089864094e-18,0.0,essential
653,HNEAP_RS03445,WP_012823568.1,502585791.0,743246,746044,2798.0,+,diguanylate cyclase,0.5248,54,0.02648053729803496,63.765133813668186,91.0,0.020920585600807305,50.37677012674399,87.0,nonessential
654,HNEAP_RS03450,WP_012823569.1,502585792.0,746029,746961,932.0,-,hypothetical protein,0.5895,18,0.9199528575170715,2215.246480901108,45.0,0.9605494248387471,2313.0030150117027,46.0,nonessential
655,HNEAP_RS03455,WP_012823570.1,502585793.0,747063,748466,1403.0,+,glutamate--tRNA ligase,0.5805,28,1.2442941908227087e-23,2.9962604115010825e-20,1.0,6.886538869283365e-23,1.6582785597234343e-19,1.0,essential
656,HNEAP_RS03460,WP_012823571.1,502585794.0,748475,750847,2372.0,+,signal transduction histidine kinase,0.5634,43,0.99999999998454,2407.9999999627726,163.0,0.9999999999946328,2407.999999987076,161.0,nonessential
657,HNEAP_RS03465,WP_041600351.1,753844734.0,751270,751461,191.0,+,hypothetical protein,0.5312,7,0.9790792263647747,2357.6227770863775,13.0,0.9834153870240999,2368.0642519540324,13.0,nonessential
658,HNEAP_RS03470,WP_012823573.1,502585796.0,751458,751793,335.0,+,hypothetical protein,0.5744,8,0.740102507632138,1782.1668383781885,15.0,0.6879397938215026,1656.5590235221782,14.0,nonessential
659,HNEAP_RS03475,WP_012823574.1,502585797.0,751830,752417,587.0,+,hypothetical protein,0.4575,27,0.01364973434627033,32.86856030581895,13.0,0.01928499008553088,46.43825612595836,13.0,nonessential
660,HNEAP_RS03480,WP_012823575.1,502585798.0,752642,752914,272.0,+,hypothetical protein,0.4615,11,0.08311332928143632,200.13689690969866,6.0,0.09863948308734258,237.52387527432091,6.0,nonessential
661,HNEAP_RS03485,WP_012823576.1,502585799.0,753140,753697,557.0,+,DUF924 domain-containing protein,0.5376,6,0.042538105734218394,102.43175860799789,14.0,0.056507441064722226,136.06991808385112,14.0,nonessential
662,HNEAP_RS03490,WP_049772560.1,908628527.0,753749,754270,521.0,-,diguanylate cyclase,0.477,6,0.49790591446037,1198.957442020571,20.0,0.5540255418199284,1334.0935047023875,20.0,nonessential
663,HNEAP_RS03495,WP_012823578.1,502585801.0,754804,756048,1244.0,-,NAD(P)/FAD-dependent oxidoreductase,0.5799,17,0.9434301500896722,2271.7798014159307,60.0,0.9648234154642996,2323.2947844380333,60.0,nonessential
664,HNEAP_RS03500,WP_012823579.1,502585802.0,756045,756602,557.0,-,hypothetical protein,0.6039,10,0.630269989819201,1517.6901354846361,23.0,0.7555997455115576,1819.4841871918306,24.0,nonessential
665,HNEAP_RS03505,WP_012823580.1,502585803.0,756609,756965,356.0,-,DUF883 domain-containing protein,0.5378,5,0.16196416301088729,390.0097045302166,10.0,0.19089433811103684,459.6735661713767,10.0,nonessential
666,HNEAP_RS03510,WP_012823581.1,502585804.0,757057,757905,848.0,-,shikimate dehydrogenase,0.5913,9,1.2174939952164647e-15,2.931725540481247e-12,0.0,3.489737046972779e-15,8.403286809110451e-12,0.0,essential
667,HNEAP_RS03515,WP_012823582.1,502585805.0,757914,758576,662.0,-,ribose-5-phosphate isomerase RpiA,0.5596,9,2.2741280016489435e-12,5.476100227970656e-09,0.0,5.174055664385338e-12,1.2459126039839895e-08,0.0,essential
668,HNEAP_RS03520,WP_012823583.1,502585806.0,758850,760373,1523.0,+,threonine ammonia-lyase  biosynthetic,0.5761,27,1.635456985265991e-27,3.9381804205205066e-24,0.0,6.717583425573972e-25,1.6175940888782125e-21,1.0,essential
669,HNEAP_RS03525,WP_012823584.1,502585807.0,761369,761836,467.0,-,EVE domain-containing protein,0.5128,12,0.41665544738694416,1003.3063173077616,17.0,0.4689699117133287,1129.2795474056954,17.0,nonessential
670,HNEAP_RS03530,WP_012823585.1,502585808.0,761854,762438,584.0,-,5-formyltetrahydrofolate cyclo-ligase,0.5556,10,0.9063547944142814,2182.5023449495893,29.0,0.9525438858008904,2293.725677008544,30.0,nonessential
671,HNEAP_RS03535,WP_012823586.1,502585809.0,762744,763415,671.0,-,S-adenosylmethionine-dependent methyltransferase,0.5268,13,0.9801740182428041,2360.2590359286723,37.0,0.9797485793708722,2359.2345791250605,36.0,nonessential
672,HNEAP_RS03540,WP_012823587.1,502585810.0,763501,765183,1682.0,-,L-aspartate oxidase,0.6031,31,2.6576899739719435e-12,6.39971745732444e-09,19.0,8.783720672980779e-13,2.1151199380537716e-09,17.0,essential
673,HNEAP_RS03545,WP_012823588.1,502585811.0,765357,765983,626.0,+,RNA polymerase sigma factor RpoE,0.5534,13,0.9999999997725068,2407.9999994521963,60.0,0.999999999491574,2407.99999877571,58.0,nonessential
674,HNEAP_RS03550,WP_012823589.1,502585812.0,766048,766710,662.0,+,hypothetical protein,0.5701,7,0.9992416565648687,2406.1739090082037,43.0,0.999779438501554,2407.468887911742,44.0,nonessential
675,HNEAP_RS03555,WP_041600352.1,753844735.0,766714,767007,293.0,+,hypothetical protein,0.5408,7,0.02356333672241592,56.740514827577535,5.0,0.02941339772427623,70.82746172005716,5.0,nonessential
676,HNEAP_RS03560,WP_081441100.1,1174219919.0,766959,767837,878.0,+,hypothetical protein,0.5745,16,0.9999999492352216,2407.9998777584137,69.0,0.9999998406378687,2407.999616255988,66.0,nonessential
677,HNEAP_RS03565,WP_012823590.1,502585813.0,767837,768388,551.0,+,positive regulator of sigma E  RseC/MucC,0.5489,11,1.292409208216439e-05,0.031121213733851853,5.0,2.2033530479378517e-05,0.05305674139434347,5.0,ambiguous
678,HNEAP_RS12180,WP_012823591.1,502585814.0,768513,769448,935.0,+,GGDEF domain-containing protein,0.5096,24,0.9382465808052597,2259.2977665790654,46.0,0.9223988137657864,2221.1363435480134,44.0,nonessential
679,HNEAP_RS03575,WP_041600354.1,753844737.0,769530,770093,563.0,+,hypothetical protein,0.5319,9,0.9998159119295961,2407.5567159264674,40.0,0.9998040185217224,2407.5280766003075,39.0,nonessential
680,HNEAP_RS03580,WP_012823593.1,502585816.0,770103,771146,1043.0,+,flagellar motor switch protein FliM,0.5489,26,0.9417064378813755,2267.6291024183524,51.0,0.9481633512139673,2283.1773497232334,50.0,nonessential
681,HNEAP_RS03585,WP_012823594.1,502585817.0,771187,771606,419.0,+,flagellar motor switch protein FliN,0.5595,6,0.8346723226732315,2009.8909529971415,20.0,0.8652077258587312,2083.4202038678245,20.0,nonessential
682,HNEAP_RS12185,WP_012823595.1,502585818.0,771612,772247,635.0,+,flagellar biosynthetic protein FliO,0.5645,11,0.2990460291705632,720.1028382427162,22.0,0.10637874038805381,256.16000685443356,18.0,nonessential
683,HNEAP_RS03595,WP_012823596.1,502585819.0,772258,773082,824.0,+,flagellar biosynthetic protein FliP,0.5248,12,0.29014947919733414,698.6799459071806,29.0,0.22581131609792326,543.7536491637992,27.0,nonessential
684,HNEAP_RS03600,WP_012823597.1,502585820.0,773125,773394,269.0,+,flagellar biosynthetic protein FliQ,0.5704,2,0.25676604606667813,618.2926389285609,8.0,0.28943832863919233,696.9674953631751,8.0,nonessential
685,HNEAP_RS03605,WP_012823598.1,502585821.0,773399,774175,776.0,+,flagellar biosynthetic protein FliR,0.5611,12,0.4161246056669208,1002.0280504459453,29.0,0.40946651748781915,985.9953741106685,28.0,nonessential
686,HNEAP_RS03610,WP_012823599.1,502585822.0,774175,775314,1139.0,+,flagellar biosynthesis protein FlhB,0.5465,11,0.6438074541747991,1550.2883496529164,47.0,0.6658082071358025,1603.2661627830123,46.0,nonessential
687,HNEAP_RS03620,WP_012823600.1,502585823.0,777530,778987,1457.0,+,flagellar biosynthesis protein FlhF,0.5871,18,0.9211834064418332,2218.209642711934,68.0,0.8728771949427107,2101.8882854220474,64.0,nonessential
688,HNEAP_RS03625,WP_012823601.1,502585824.0,779042,779872,830.0,+,MinD/ParA family protein,0.5403,9,0.907440478859403,2185.1166730934424,40.0,0.9101645500811106,2191.6762365953145,39.0,nonessential
689,HNEAP_RS03630,WP_012823602.1,502585825.0,779872,780591,719.0,+,RNA polymerase sigma factor FliA,0.5333,15,0.9999345779407962,2407.8424636814375,50.0,0.9998866508980354,2407.7270553624694,48.0,nonessential
690,HNEAP_RS03635,WP_012823603.1,502585826.0,780887,781273,386.0,+,chemotaxis protein CheY,0.5116,6,0.9876085587572855,2378.1614094875436,24.0,0.9976003065012986,2402.221538055127,26.0,nonessential
691,HNEAP_RS03640,WP_081441101.1,1174219920.0,781374,782129,755.0,+,hypothetical protein,0.5278,10,0.11104155389464881,267.38806177831435,23.0,0.07115222496522314,171.3345577162573,21.0,nonessential
692,HNEAP_RS03645,WP_012823605.1,502585828.0,782171,784330,2159.0,+,chemotaxis protein CheA,0.5574,32,0.6275127855721685,1511.0507876577817,88.0,0.7303082489714128,1758.582263523162,88.0,nonessential
693,HNEAP_RS03650,WP_012823606.1,502585829.0,784335,785387,1052.0,+,chemotaxis response regulator protein-glutamate methylesterase,0.5878,13,0.4308146716446118,1037.4017293202253,40.0,0.4460762674366452,1074.1516519874417,39.0,nonessential
694,HNEAP_RS03655,WP_012823607.1,502585830.0,785384,786238,854.0,+,ParA family protein,0.5485,17,0.9058068010712809,2181.182776979644,41.0,0.9093317609718916,2189.670880420315,40.0,nonessential
695,HNEAP_RS03660,WP_012823608.1,502585831.0,786235,787104,869.0,+,hypothetical protein,0.5483,13,0.9849055257282352,2371.65250595359,47.0,0.9908607122122144,2385.9925950070124,47.0,nonessential
696,HNEAP_RS03665,WP_041600674.1,753845057.0,787170,787640,470.0,+,hypothetical protein,0.5308,9,0.23297939412844185,561.014381061288,15.0,0.19691873519218067,474.18031434277106,14.0,nonessential
697,HNEAP_RS03670,WP_012823610.1,502585833.0,787637,788071,434.0,+,DUF2802 domain-containing protein,0.531,4,0.7208314850648606,1735.7622160361843,19.0,0.49481797401845995,1191.5216814364517,16.0,nonessential
698,HNEAP_RS03675,WP_012823611.1,502585834.0,788244,790250,2006.0,-,DUF3488 domain-containing protein,0.5655,44,0.8699904540270416,2094.937013297116,89.0,0.9027663061763769,2173.8612652727156,88.0,nonessential
699,HNEAP_RS03680,WP_012823612.1,502585835.0,790247,791155,908.0,-,DUF58 domain-containing protein,0.571,20,0.9999348109282662,2407.843024715265,60.0,0.9998365771815216,2407.606477853104,57.0,nonessential
700,HNEAP_RS03685,WP_012823613.1,502585836.0,791368,792459,1091.0,+,AI-2E family transporter,0.5412,22,0.04229255068205568,101.84046204239009,32.0,0.04449888556814157,107.15331644808491,31.0,nonessential
701,HNEAP_RS03690,WP_012823614.1,502585837.0,792500,793201,701.0,+,DnaA regulatory inactivator Hda,0.5413,12,1.404739251559208e-11,3.3826121177545726e-08,1.0,3.2532343703864583e-11,7.833788363890592e-08,1.0,essential
702,HNEAP_RS03695,WP_012823615.1,502585838.0,793214,793795,581.0,-,hypothetical protein,0.5052,20,0.8285660312581302,1995.1870032695776,27.0,0.8157526408272118,1964.332359111926,26.0,nonessential
703,HNEAP_RS03700,WP_012823616.1,502585839.0,793935,794336,401.0,-,hypothetical protein,0.4801,7,0.07618137235068702,183.44474462045434,10.0,0.05352436671704065,128.88667505463388,9.0,nonessential
704,HNEAP_RS03705,WP_012823617.1,502585840.0,794415,795173,758.0,-,phosphatase,0.5705,13,0.9911490896255089,2386.6870078182255,43.0,0.9867526519989227,2376.100386013406,41.0,nonessential
705,HNEAP_RS03710,WP_012823618.1,502585841.0,795288,796130,842.0,+,hypothetical protein,0.5326,19,0.5166245679496848,1244.031959622841,33.0,0.6544714229640707,1575.967186497482,34.0,nonessential
706,HNEAP_RS03715,WP_012823619.1,502585842.0,796253,796738,485.0,-,peptidyl-prolyl cis-trans isomerase,0.5329,7,0.9223785233398445,2221.0874842023454,25.0,0.941106420284266,2266.1842600445125,25.0,nonessential
707,HNEAP_RS03720,WP_012823620.1,502585843.0,796769,797590,821.0,-,UTP--glucose-1-phosphate uridylyltransferase,0.5438,22,2.2160932006652506e-12,5.336352427201923e-09,2.0,5.775442256883399e-12,1.3907264954575225e-08,2.0,essential
708,HNEAP_RS03725,WP_012823621.1,502585845.0,797683,798051,368.0,-,DUF2069 domain-containing protein,0.5583,7,0.9999849594340632,2407.9637823172243,32.0,0.9999918387132507,2407.980347621508,32.0,nonessential
709,HNEAP_RS03730,WP_012823622.1,502585846.0,798052,798645,593.0,-,NAD(P)H:quinone oxidoreductase,0.5842,9,0.977523425868587,2353.8764094915573,33.0,0.9906754649153592,2385.546519516185,34.0,nonessential
710,HNEAP_RS03735,WP_012823623.1,502585847.0,798899,799411,512.0,+,TlpA family protein disulfide reductase,0.5068,12,0.26840716595962044,646.324455630766,17.0,0.23538919550533347,566.817182776843,16.0,nonessential
711,HNEAP_RS03740,WP_012823624.1,502585848.0,799466,800059,593.0,+,hypothetical protein,0.5067,8,0.999722203446244,2407.3310658985556,41.0,0.9998519632090985,2407.6435274075093,41.0,nonessential
712,HNEAP_RS03745,WP_012823625.1,502585849.0,800122,801459,1337.0,+,TolC family protein,0.5643,30,0.6907009579228838,1663.2079066783042,56.0,0.6212595416664213,1495.9929763327425,53.0,nonessential
713,HNEAP_RS03750,WP_012823626.1,502585850.0,801456,802328,872.0,+,hypothetical protein,0.5716,13,0.999999824544493,2407.9995775031393,67.0,0.9999999418687959,2407.9998600200606,67.0,nonessential
714,HNEAP_RS03755,WP_012823627.1,502585851.0,802344,804122,1778.0,-,N-acetylglutaminylglutamine amidotransferase,0.5913,28,0.7294908260816386,1756.6139092045858,75.0,0.5102973785836369,1228.7960876293976,68.0,nonessential
715,HNEAP_RS03760,WP_012823628.1,502585852.0,804162,806168,2006.0,+,FAD-dependent oxidoreductase,0.5795,26,0.17722580737824778,426.75974416682067,71.0,0.21971285270347596,529.0685493099701,70.0,nonessential
716,HNEAP_RS03765,WP_012823629.1,502585853.0,806171,806440,269.0,-,HPr family phosphocarrier protein,0.5519,0,0.15999440653029162,385.26653092494223,7.0,0.18461787150537884,444.5598345849522,7.0,nonessential
717,HNEAP_RS03770,WP_012823630.1,502585854.0,806440,806832,392.0,-,PTS mannose transporter subunit IIA,0.5293,9,0.9999473263640232,2407.8731618845677,32.0,0.999843933322456,2407.624191440474,30.0,nonessential
718,HNEAP_RS03775,WP_012823631.1,502585855.0,807263,808126,863.0,-,RNase adapter RapZ,0.5289,24,0.025285699380166345,60.88796410744056,23.0,0.0372548271529697,89.70962378435102,23.0,nonessential
719,HNEAP_RS12190,WP_049772462.1,908628429.0,808226,809086,860.0,-,hypothetical protein,0.547,13,0.6041539145381052,1454.8026262077574,35.0,0.5386424264499591,1297.0509628915015,33.0,nonessential
720,HNEAP_RS03785,WP_012823633.1,502585857.0,809111,809590,479.0,-,PTS IIA-like nitrogen-regulatory protein PtsN,0.5437,6,5.6476343145133e-06,0.013599503429348027,3.0,9.354608225750632e-06,0.022525896607607523,3.0,essential
721,HNEAP_RS03790,WP_012823635.1,502585859.0,809986,810276,290.0,-,ribosomal subunit interface protein,0.4467,7,0.05640959002145331,135.83429277165956,6.0,0.06833246645325734,164.54457921944368,6.0,nonessential
722,HNEAP_RS03795,WP_012823636.1,502585860.0,810295,811803,1508.0,-,RNA polymerase sigma-54 factor,0.5646,24,6.0171637146572605e-24,1.4489330224894683e-20,2.0,1.1521622561694184e-20,2.7744067128559595e-17,4.0,essential
723,HNEAP_RS03800,WP_012823637.1,502585861.0,811966,812709,743.0,-,LPS export ABC transporter ATP-binding protein,0.5726,16,2.7124087715460042e-12,6.5314803218827785e-09,1.0,6.61758868457318e-12,1.5935153552452215e-08,1.0,essential
724,HNEAP_RS03805,WP_012823638.1,502585862.0,812706,813290,584.0,-,lipopolysaccharide transport periplasmic protein LptA,0.5368,10,5.353903650435574e-11,1.289219999024886e-07,0.0,1.1056594711008309e-10,2.662428006410801e-07,0.0,essential
725,HNEAP_RS03810,WP_081441102.1,1174219921.0,813290,813964,674.0,-,LPS export ABC transporter periplasmic protein LptC,0.5585,11,4.036368297766647e-11,9.719574861022086e-08,1.0,9.039978647910271e-11,2.1768268584167933e-07,1.0,essential
726,HNEAP_RS03815,WP_012823640.1,502585864.0,813930,814457,527.0,-,haloacid dehalogenase,0.589,6,0.0009850964596150361,2.372112274753007,8.0,0.0037026380712817768,8.915952475646518,9.0,nonessential
727,HNEAP_RS03820,WP_012823641.1,502585865.0,814495,815466,971.0,-,KpsF/GutQ family sugar-phosphate isomerase,0.5885,9,7.067740032756491e-15,1.701911799887763e-11,2.0,2.946729651670197e-13,7.095725001221835e-10,3.0,essential
728,HNEAP_RS03825,WP_012823642.1,502585866.0,815790,816653,863.0,+,hypothetical protein,0.5718,18,0.9976780969341653,2402.4088574174702,51.0,0.9987586470427527,2405.0108220789484,51.0,nonessential
729,HNEAP_RS03830,WP_012823643.1,502585867.0,816650,817189,539.0,+,hypothetical protein,0.5852,9,0.9999925218381467,2407.981992586257,43.0,0.9999824833702852,2407.9578199556468,41.0,nonessential
730,HNEAP_RS03835,WP_012823644.1,502585868.0,817189,818058,869.0,+,ABC transporter ATP-binding protein,0.6034,10,0.8863780555787061,2134.398357833524,41.0,0.8563364990259976,2062.058289654602,39.0,nonessential
731,HNEAP_RS03840,WP_012823645.1,502585869.0,818055,818855,800.0,+,ABC transporter permease,0.5705,10,0.9999998383474,2407.999610740539,63.0,0.999998823193236,2407.997166249312,59.0,nonessential
732,HNEAP_RS03845,WP_041600683.1,753845066.0,818859,819320,461.0,+,outer membrane lipid asymmetry maintenance protein MlaD,0.4957,15,0.9999894142165205,2407.9745094333816,38.0,0.9999946848313584,2407.9872010739114,38.0,nonessential
733,HNEAP_RS03850,WP_012823647.1,502585871.0,819317,820678,1361.0,+,TolC family protein,0.5514,38,0.9999754665450374,2407.94092344045,85.0,0.9999858217892396,2407.965858868489,84.0,nonessential
734,HNEAP_RS03855,WP_012823648.1,502585872.0,820675,821316,641.0,+,toluene tolerance family protein,0.5202,15,0.6708358754032413,1615.372787971005,27.0,0.7260234508993204,1748.2644697655635,27.0,nonessential
735,HNEAP_RS03860,WP_012823649.1,502585873.0,821309,821662,353.0,+,STAS domain-containing protein,0.596,7,0.8865835746783479,2134.893247825462,18.0,0.8595441772890904,2069.78237891213,17.0,nonessential
736,HNEAP_RS03865,WP_012823650.1,502585874.0,821727,822986,1259.0,+,UDP-N-acetylglucosamine 1-carboxyvinyltransferase,0.5548,22,7.191886906997976e-23,1.7318063672051124e-19,0.0,3.4341619463156657e-22,8.269461966728123e-19,0.0,essential
737,HNEAP_RS03870,WP_012823651.1,502585875.0,823018,823668,650.0,+,ATP phosphoribosyltransferase,0.5545,15,3.697171703262828e-12,8.90278946145689e-09,0.0,8.287322101887595e-12,1.995587162134533e-08,0.0,essential
738,HNEAP_RS03875,WP_012823652.1,502585876.0,823665,824966,1301.0,+,histidinol dehydrogenase,0.5845,19,7.189267600216437e-22,1.731175638132118e-18,1.0,3.505680428398554e-21,8.441678471583718e-18,1.0,essential
739,HNEAP_RS03880,WP_012823653.1,502585877.0,825041,826150,1109.0,+,histidinol-phosphate transaminase,0.5441,23,4.555902877223758e-13,1.097061412835481e-09,6.0,1.2765487765546276e-16,3.0739294539435433e-13,2.0,essential
740,HNEAP_RS03890,WP_012823654.1,502585878.0,826389,828164,1775.0,+,DNA polymerase III  subunit gamma and tau,0.5479,25,1.67095130372849e-28,4.023650739378204e-25,2.0,1.4223584255398237e-27,3.4250390886998954e-24,2.0,essential
741,HNEAP_RS03895,WP_012823655.1,502585879.0,828206,828532,326.0,+,nucleoid-associated protein  YbaB/EbfC family,0.5291,3,0.0001938044859517106,0.4666812021717191,2.0,0.0002739353064173753,0.6596362178530397,2.0,nonessential
742,HNEAP_RS03900,WP_012823656.1,502585880.0,828543,829136,593.0,+,recombination protein RecR,0.5572,11,0.9858001609367919,2373.8067875357947,34.0,0.9967574146654279,2400.1918545143503,36.0,nonessential
743,HNEAP_RS03905,WP_012823657.1,502585881.0,829163,829534,371.0,-,PilZ domain-containing protein,0.4409,6,0.0008940397718735237,2.152847770671445,4.0,0.0012600166377711754,3.03412006375299,4.0,nonessential
744,HNEAP_RS03910,WP_012823658.1,502585882.0,829535,831709,2174.0,-,DUF1631 domain-containing protein,0.4492,71,0.42874334645033346,1032.413978252403,84.0,0.49845447924798214,1200.278386029141,83.0,nonessential
745,HNEAP_RS03915,WP_012823659.1,502585884.0,831681,833150,1469.0,-,glycogen synthase GlgA,0.4952,40,0.9992848562982676,2406.2779339662284,83.0,0.9995504951956842,2406.9175924312076,82.0,nonessential
746,HNEAP_RS03920,WP_012823660.1,502585885.0,833167,835332,2165.0,-,1 4-alpha-glucan-branching protein,0.5254,44,0.9939468177822003,2393.4239372195384,109.0,0.9917281279735942,2388.081332160415,105.0,nonessential
747,HNEAP_RS03925,WP_012823661.1,502585886.0,835747,837018,1271.0,+,glucose-1-phosphate adenylyltransferase,0.5299,29,0.9999980530006297,2407.9953116255165,85.0,0.9999810678261862,2407.9544113254565,79.0,nonessential
748,HNEAP_RS03930,WP_012823662.1,502585887.0,837018,838718,1700.0,+,glycoside hydrolase,0.5267,35,0.9801363507429601,2360.168332589048,84.0,0.9862618816242835,2374.918610951275,83.0,nonessential
749,HNEAP_RS03935,WP_041600687.1,753845070.0,838760,840190,1430.0,+,4-alpha-glucanotransferase,0.5737,25,0.7842462002830478,1888.4648502815792,62.0,0.6389514905563434,1538.5951892596747,57.0,nonessential
750,HNEAP_RS03945,WP_041600357.1,753844740.0,841567,841770,203.0,+,hypothetical protein,0.4167,5,0.0025252937277412766,6.080907296400994,1.0,0.0031585178835053522,7.605711063480888,1.0,nonessential
751,HNEAP_RS03950,WP_012823665.1,502585890.0,842110,843315,1205.0,-,multidrug ABC transporter substrate-binding protein,0.568,16,0.99999999600591,2407.9999903822313,91.0,0.9999999980575421,2407.9999953225615,90.0,nonessential
752,HNEAP_RS03955,WP_012823666.1,502585891.0,843315,844031,716.0,-,ABC transporter ATP-binding protein,0.5914,10,0.9090844285021242,2189.075303833115,35.0,0.8740469605691705,2104.7050810505625,33.0,nonessential
753,HNEAP_RS03960,WP_012823667.1,502585892.0,844028,845314,1286.0,-,efflux RND transporter periplasmic adaptor subunit,0.5742,17,0.9996813115470824,2407.2325982053744,76.0,0.9998701990976374,2407.687439427111,76.0,nonessential
754,HNEAP_RS03965,WP_012823668.1,502585893.0,845311,846792,1481.0,-,RND transporter,0.5803,21,0.9999993954753315,2407.998544304598,98.0,0.9999998424277411,2407.9996205660004,98.0,nonessential
755,HNEAP_RS03975,WP_012823669.1,502585894.0,847412,848857,1445.0,-,two-component sensor histidine kinase,0.5698,28,0.9999725413386475,2407.9338795434633,89.0,0.9999581689559196,2407.8992708458545,86.0,nonessential
756,HNEAP_RS03980,WP_012823670.1,502585895.0,848857,849537,680.0,-,DNA-binding response regulator,0.58,10,0.9999999991183992,2407.999997877105,62.0,0.9999999997282342,2407.999999345588,62.0,nonessential
757,HNEAP_RS03985,WP_012823671.1,502585896.0,849673,851031,1358.0,+,TolC family protein,0.5725,24,0.9998992000901747,2407.7572738171407,82.0,0.9997411483748684,2407.376685286683,78.0,nonessential
758,HNEAP_RS03990,WP_012823672.1,502585897.0,851035,852132,1097.0,+,efflux RND transporter periplasmic adaptor subunit,0.5874,11,0.9938661503550016,2393.229690054844,60.0,0.9892276960369621,2382.060292057005,57.0,nonessential
759,HNEAP_RS03995,WP_012823673.1,502585898.0,852129,855188,3059.0,+,AcrB/AcrD/AcrF family protein,0.5804,48,0.9723594084976293,2341.4414556622914,142.0,0.9773193138053405,2353.38490764326,139.0,nonessential
760,HNEAP_RS04000,WP_049772565.1,908628532.0,855307,855648,341.0,+,hypothetical protein,0.538,5,0.863232012439862,2078.662685955188,17.0,0.887701662464469,2137.5856032144416,17.0,nonessential
761,HNEAP_RS04005,WP_012823675.1,502585900.0,856209,857192,983.0,+,ABC transporter substrate-binding protein,0.5427,17,0.9999999999999999,2407.9999999999995,100.0,0.9999999999999999,2407.9999999999995,97.0,nonessential
762,HNEAP_RS04010,WP_041600358.1,753844741.0,857226,858197,971.0,+,nitrate ABC transporter permease,0.571,20,0.9973709816932074,2401.669323917243,56.0,0.9965631607490355,2399.7240910836776,54.0,nonessential
763,HNEAP_RS04015,WP_012823677.1,502585902.0,858250,859176,926.0,+,ABC transporter ATP-binding protein,0.5858,7,0.9999808890139256,2407.9539807455326,63.0,0.9999733062164923,2407.9357213693133,61.0,nonessential
764,HNEAP_RS04020,WP_012823678.1,502585903.0,859190,859987,797.0,+,creatininase,0.5664,10,0.9999998583925123,2407.9996590091696,63.0,0.9999999904949977,2407.999977111954,65.0,nonessential
765,HNEAP_RS04025,WP_012823679.1,502585904.0,859990,861375,1385.0,+,type III glutamate--ammonia ligase,0.5859,21,0.999999999999943,2407.9999999998627,116.0,0.9999999999999085,2407.99999999978,113.0,nonessential
766,HNEAP_RS04030,WP_012823680.1,502585905.0,861408,861854,446.0,+,nickel-responsive transcriptional regulator NikR,0.5324,7,0.8758135965557377,2108.959140506216,22.0,0.7976158253316747,1920.6589073986727,20.0,nonessential
767,HNEAP_RS04035,WP_012823681.1,502585906.0,862196,862933,737.0,+,urea carboxylase,0.5691,11,0.9999990083722264,2407.9976121603213,57.0,0.9999996179752516,2407.9990800844057,57.0,nonessential
768,HNEAP_RS04040,WP_012823682.1,502585907.0,862943,863581,638.0,+,urea carboxylase,0.5509,18,0.9998100838075471,2407.5426818085734,44.0,0.9993402146675233,2406.4112369193963,41.0,nonessential
769,HNEAP_RS04045,WP_012823683.1,502585908.0,863706,867332,3626.0,+,urea carboxylase,0.6068,60,0.991182383512751,2386.7671794987045,172.0,0.990645357504123,2385.474020869928,167.0,nonessential
770,HNEAP_RS04055,WP_041600691.1,753845074.0,867758,869947,2189.0,+,primosomal protein N',0.6041,24,4.030369809029261e-34,9.70513050014246e-31,3.0,1.88243181764445e-34,4.532895816887835e-31,2.0,essential
771,HNEAP_RS04060,WP_012823685.1,502585910.0,870006,870344,338.0,+,P-II family nitrogen regulator,0.5221,5,0.7288587339779459,1755.0918314188937,15.0,0.6759810124821647,1627.7622780570525,14.0,nonessential
772,HNEAP_RS04065,WP_012823686.1,502585911.0,870494,871597,1103.0,-,glycine oxidase ThiO,0.5996,16,0.9999330536063942,2407.8387930841973,70.0,0.9993899174061384,2406.530921113981,64.0,nonessential
773,HNEAP_RS04075,WP_012823687.1,502585912.0,871881,872591,710.0,-,VIT family protein,0.5724,17,0.6807188174643755,1639.170912454216,30.0,0.7378186945113967,1776.6674163834432,30.0,nonessential
774,HNEAP_RS04080,WP_012823688.1,502585913.0,872656,872880,224.0,+,hypothetical protein,0.44,8,0.9999961124866099,2407.990638867757,24.0,0.9999977111294137,2407.994488399628,24.0,nonessential
775,HNEAP_RS04085,WP_012823689.1,502585914.0,872893,875013,2120.0,+,bifunctional (p)ppGpp synthetase/guanosine-3' 5'-bis(diphosphate) 3'-pyrophosphohydrolase,0.6035,41,0.9421928403544065,2268.800359573411,98.0,0.908190143164036,2186.921864738999,93.0,nonessential
776,HNEAP_RS04090,WP_012823690.1,502585915.0,875035,875487,452.0,-,hypothetical protein,0.4283,17,0.5680623903552094,1367.8942359753444,18.0,0.6193389014770655,1491.3680747567737,18.0,nonessential
777,HNEAP_RS04095,WP_012823691.1,502585916.0,875905,876507,602.0,+,DUF3365 domain-containing protein,0.534,9,0.9588049385868774,2308.802292117201,32.0,0.9710737852851986,2338.3456749667585,32.0,nonessential
778,HNEAP_RS04100,WP_012823692.1,502585917.0,876582,877691,1109.0,-,molybdenum ABC transporter ATP-binding protein,0.5514,16,0.7098233072814231,1709.2545239336666,47.0,0.6195585890702238,1491.8970824810988,44.0,nonessential
779,HNEAP_RS04105,WP_012823693.1,502585918.0,877695,878387,692.0,-,molybdate ABC transporter permease subunit,0.5296,16,0.22360729967092094,538.4463776075776,23.0,0.273833373174328,659.3907626037818,23.0,nonessential
780,HNEAP_RS04110,WP_012823694.1,502585919.0,878741,879511,770.0,-,molybdate ABC transporter substrate-binding protein,0.5292,18,0.7706031898826601,1855.6124812374455,34.0,0.5009793563570004,1206.358290107657,29.0,nonessential
781,HNEAP_RS04115,WP_012823695.1,502585920.0,879603,880406,803.0,-,ModE family transcriptional regulator,0.551,13,0.9855345484569259,2373.167192684278,44.0,0.9793979977271977,2358.3903785270923,42.0,nonessential
782,HNEAP_RS12195,WP_081441103.1,1174219922.0,880522,880974,452.0,-,hypothetical protein,0.543,8,0.9952036756765082,2396.4504510290317,29.0,0.9897571629870837,2383.3352484728975,27.0,nonessential
783,HNEAP_RS04120,WP_081441104.1,1174219923.0,880884,881744,860.0,-,hypothetical protein,0.5308,17,0.8983239610266797,2163.1640981522446,41.0,0.8701970380720332,2095.434467677456,39.0,nonessential
784,HNEAP_RS04125,WP_012823697.1,502585923.0,881975,883447,1472.0,-,deoxyribodipyrimidine photo-lyase,0.5682,31,0.9999999982553162,2407.999995798801,107.0,0.9999999986586063,2407.999996769924,105.0,nonessential
785,HNEAP_RS04130,WP_012823698.1,502585924.0,883540,884700,1160.0,+,efflux RND transporter periplasmic adaptor subunit,0.5866,17,0.9939597352482421,2393.455042477767,63.0,0.9952769480148513,2396.626890819762,62.0,nonessential
786,HNEAP_RS04135,WP_012823699.1,502585925.0,884697,887804,3107.0,+,AcrB/AcrD/AcrF family protein,0.5759,63,0.9999999999111931,2407.9999997861532,198.0,0.9999999992088546,2407.999998094922,189.0,nonessential
787,HNEAP_RS04150,WP_012823700.1,502585926.0,890923,891213,290.0,-,CRISPR-associated endonuclease Cas2,0.4536,7,0.10840342558228455,261.0354488021412,7.0,0.12800463098132284,308.2351514030254,7.0,nonessential
788,HNEAP_RS04155,WP_012823701.1,502585927.0,891222,892256,1034.0,-,type I-C CRISPR-associated endonuclease Cas1,0.544,19,0.8810565405658275,2121.584149682513,48.0,0.8225489541679928,1980.6978816365265,45.0,nonessential
789,HNEAP_RS04160,WP_081441105.1,1174219924.0,892259,892609,350.0,+,ribbon-helix-helix protein  CopG family,0.5413,8,8.368394097505264e-05,0.20151092986792676,2.0,1.6197707359794065e-05,0.03900407932238411,1.0,ambiguous
790,HNEAP_RS04165,WP_012823703.1,502585929.0,892609,892962,353.0,+,type II toxin-antitoxin system PemK/MazF family toxin,0.5791,5,0.5693633309394208,1371.0269009021254,14.0,0.5073345301283112,1221.6615485489733,13.0,nonessential
791,HNEAP_RS04170,WP_012823704.1,502585930.0,892946,893566,620.0,-,CRISPR-associated protein Cas4,0.5636,9,0.996278107818433,2399.0376836267865,38.0,0.993471959473589,2392.2804784124023,36.0,nonessential
792,HNEAP_RS04175,WP_012823705.1,502585931.0,893595,894470,875.0,-,type I-C CRISPR-associated protein Cas7/Csd2,0.524,22,0.9831503348523519,2367.4260063244633,47.0,0.9845636455300181,2370.8292584362835,46.0,nonessential
793,HNEAP_RS04180,WP_012823706.1,502585932.0,894467,896203,1736.0,-,type I-C CRISPR-associated protein Cas8c/Csd1,0.5469,43,0.9999998715274542,2407.9996906381098,114.0,0.99999973100442,2407.9993522586433,110.0,nonessential
794,HNEAP_RS04185,WP_012823707.1,502585933.0,896200,896865,665.0,-,type I-C CRISPR-associated protein Cas5,0.5811,12,0.9416919754056757,2267.594276776867,34.0,0.9587116846491758,2308.5777366352154,34.0,nonessential
795,HNEAP_RS04190,WP_012823708.1,502585934.0,896874,899135,2261.0,-,CRISPR-associated helicase/endonuclease Cas3,0.5367,43,0.9999127235299791,2407.7898382601898,126.0,0.999919287515504,2407.8056443373334,123.0,nonessential
796,HNEAP_RS04195,WP_012823709.1,502585935.0,899223,899411,188.0,-,addiction module antidote protein  HigA family,0.5291,2,0.37935725006408283,913.4922581543115,6.0,0.41151460267309425,990.927163236811,6.0,nonessential
797,HNEAP_RS04200,WP_081441179.1,1174219998.0,899715,900101,386.0,-,hypothetical protein,0.491,10,0.3290098005137991,792.2555996372282,13.0,0.27465277212194844,661.3638752696519,12.0,nonessential
798,HNEAP_RS04205,WP_012823710.1,502585936.0,900230,901828,1598.0,-,gamma-glutamyltransferase family protein,0.5997,37,0.9999999999999919,2407.9999999999804,131.0,0.999999999999998,2407.999999999995,130.0,nonessential
799,HNEAP_RS04210,WP_012823711.1,502585937.0,901866,903188,1322.0,-,C4-dicarboxylate ABC transporter,0.5654,22,0.9999314292712063,2407.834881685065,81.0,0.9995339784465767,2406.8778200993565,75.0,nonessential
800,HNEAP_RS04215,WP_012823712.1,502585938.0,903191,903781,590.0,-,C4-dicarboxylate ABC transporter permease,0.5076,21,0.9999999999999999,2407.9999999999995,73.0,0.9999999999999999,2407.9999999999995,73.0,nonessential
801,HNEAP_RS04220,WP_012823713.1,502585939.0,903809,904900,1091.0,-,C4-dicarboxylate ABC transporter,0.5348,28,0.9996182753927894,2407.080807145837,66.0,0.9992526643512427,2406.2004157577926,63.0,nonessential
802,HNEAP_RS04225,WP_012823714.1,502585940.0,905267,905713,446.0,+,Lrp/AsnC family transcriptional regulator,0.5078,12,0.9928067942719915,2390.6787606069556,28.0,0.9951923284002702,2396.4231267878504,28.0,nonessential
803,HNEAP_RS04230,WP_012823715.1,502585941.0,906081,906824,743.0,+,GntR family transcriptional regulator,0.5013,19,0.17493631579022076,421.2466484228516,24.0,0.11967641510274139,288.1808075674013,22.0,nonessential
804,HNEAP_RS04235,WP_012823716.1,502585942.0,906859,908055,1196.0,+,hypothetical protein,0.5322,25,0.8813528776131766,2122.2977292925293,55.0,0.8678878801476697,2089.8740153955887,53.0,nonessential
805,HNEAP_RS04240,WP_012823717.1,502585943.0,908052,908996,944.0,+,allantoinase PuuE,0.546,26,0.700130892268142,1685.915188581686,40.0,0.8105011133047867,1951.6866808379264,41.0,nonessential
806,HNEAP_RS04245,WP_012823718.1,502585944.0,908987,909487,500.0,+,OHCU decarboxylase,0.521,4,0.573218698515507,1380.3106260253408,20.0,0.537617255353461,1294.5823508911342,19.0,nonessential
807,HNEAP_RS04250,WP_012823719.1,502585945.0,909553,911103,1550.0,+,ABC transporter ATP-binding protein,0.5674,25,0.9999975360609905,2407.994066834865,99.0,0.9999988212139893,2407.997161483286,98.0,nonessential
808,HNEAP_RS04255,WP_012823720.1,502585946.0,911096,912205,1109.0,+,ABC transporter permease,0.5477,26,0.9999849172383029,2407.963680709833,73.0,0.9999945152232902,2407.9867926576826,73.0,nonessential
809,HNEAP_RS04260,WP_012823721.1,502585947.0,912202,913128,926.0,+,ABC transporter permease,0.5599,24,0.9999992597533592,2407.998217486089,68.0,0.9999997465909158,2407.9993897909253,68.0,nonessential
810,HNEAP_RS04265,WP_012823722.1,502585948.0,913168,914580,1412.0,+,8-oxoguanine deaminase,0.5973,15,0.9961724762424069,2398.783322791716,76.0,0.9973438831199863,2401.604070552927,75.0,nonessential
811,HNEAP_RS04270,WP_012823723.1,502585949.0,914577,915113,536.0,+,nucleoside deaminase,0.5475,10,0.5335503954275758,1284.7893521896024,21.0,0.6727009037848803,1619.8637763139918,22.0,nonessential
812,HNEAP_RS04275,WP_012823724.1,502585950.0,915103,915738,635.0,+,uracil phosphoribosyltransferase,0.5708,16,0.9967343089703236,2400.136216000539,39.0,0.9943352007524873,2394.3591634119894,37.0,nonessential
813,HNEAP_RS04280,WP_012823725.1,502585951.0,915761,917032,1271.0,+,cytosine deaminase,0.6022,21,0.9999817753097072,2407.956114945775,81.0,0.9999677011129244,2407.922224279922,78.0,nonessential
814,HNEAP_RS04285,WP_041600698.1,753845081.0,917048,917446,398.0,-,DUF3225 domain-containing protein,0.5464,5,0.9999979101163948,2407.994967560279,36.0,0.9999973047341015,2407.9935097997163,35.0,nonessential
815,HNEAP_RS04290,WP_012823727.1,502585953.0,917496,918890,1394.0,-,AtzE family amidohydrolase,0.6186,23,0.9999999999905702,2407.999999977293,110.0,0.9999999999323879,2407.99999983719,105.0,nonessential
816,HNEAP_RS04295,WP_012823728.1,502585954.0,918902,919096,194.0,-,DUF4089 domain-containing protein,0.5231,3,0.21475881796658106,517.1392336635272,5.0,0.23959617894662424,576.9475989034712,5.0,nonessential
817,HNEAP_RS04300,WP_012823729.1,502585955.0,919086,919796,710.0,-,cysteine hydrolase,0.6006,9,0.025634159788598555,61.72705677094532,18.0,0.03637146156828092,87.58247945642046,18.0,nonessential
818,HNEAP_RS04305,WP_012823730.1,502585956.0,919793,921382,1589.0,-,ABC transporter ATP-binding protein,0.5742,31,0.999999999995122,2407.999999988254,122.0,0.9999999999985542,2407.9999999965185,121.0,nonessential
819,HNEAP_RS04310,WP_012823731.1,502585957.0,921379,922062,683.0,-,cysteine hydrolase,0.5775,10,0.9959880684492655,2398.3392688258314,41.0,0.9986306967337342,2404.702717734832,42.0,nonessential
820,HNEAP_RS04315,WP_012823732.1,502585958.0,922096,923028,932.0,-,ABC transporter permease,0.5949,19,0.9999997693404586,2407.9994445718244,70.0,0.999990679272686,2407.977555688628,63.0,nonessential
821,HNEAP_RS04320,WP_012823733.1,502585959.0,923025,924113,1088.0,-,ABC transporter permease,0.5813,20,0.8709690983537841,2097.293588835912,50.0,0.8832476618156893,2126.8603696521795,49.0,nonessential
822,HNEAP_RS04325,WP_012823734.1,502585960.0,924203,925321,1118.0,-,BMP family ABC transporter substrate-binding protein,0.5442,28,0.9958967645018774,2398.1194089205205,62.0,0.9967781964179259,2400.2418969743653,61.0,nonessential
823,HNEAP_RS04330,WP_012823735.1,502585961.0,925361,926305,944.0,-,hypothetical protein,0.5175,36,5.040304642222047e-05,0.1213705357847069,16.0,9.992241839548751e-05,0.24061318349633393,16.0,nonessential
824,HNEAP_RS04335,WP_012823736.1,502585962.0,926686,927402,716.0,+,GntR family transcriptional regulator,0.5425,13,0.9543023617240153,2297.960087031429,37.0,0.9686570054995146,2332.526069242831,37.0,nonessential
825,HNEAP_RS04340,WP_081441106.1,1174219925.0,927403,928422,1019.0,-,hypothetical protein,0.5667,23,0.9999999493137215,2407.9998779474413,77.0,0.9999998709609448,2407.999689273955,74.0,nonessential
826,HNEAP_RS04345,WP_012823738.1,502585965.0,928389,928880,491.0,-,nucleoside deaminase,0.5467,10,0.6054953488611808,1458.0328000577235,20.0,0.7364229681696386,1773.3065073524897,21.0,nonessential
827,HNEAP_RS12200,WP_012823739.1,502585966.0,928873,929898,1025.0,-,xanthine dehydrogenase accessory protein XdhC,0.5702,17,0.6230289073469925,1500.2536088915579,42.0,0.576694965611175,1388.6814771917093,40.0,nonessential
828,HNEAP_RS04355,WP_012823740.1,502585967.0,929891,932275,2384.0,-,xanthine dehydrogenase molybdopterin binding subunit,0.5845,40,0.9999999229973984,2407.9998145777354,148.0,0.9999999790149089,2407.9999494679005,147.0,nonessential
829,HNEAP_RS04360,WP_012823741.1,502585968.0,932268,933782,1514.0,-,xanthine dehydrogenase small subunit,0.5683,24,0.9999999989022712,2407.999997356669,110.0,0.9999999888648394,2407.999973186533,104.0,nonessential
830,HNEAP_RS04365,WP_012823742.1,502585969.0,933785,934138,353.0,-,hydroxyisourate hydrolase,0.5028,14,0.5693633309394208,1371.0269009021254,14.0,0.6147982693680141,1480.434232638178,14.0,nonessential
831,HNEAP_RS04370,WP_012823743.1,502585970.0,934435,935610,1175.0,+,amidase,0.5493,22,0.9984130289259315,2404.178573653643,67.0,0.9992531418878574,2406.2015656659605,67.0,nonessential
832,HNEAP_RS04375,WP_012823745.1,502585972.0,935701,936519,818.0,+,sulfite exporter TauE/SafE family protein,0.558,19,0.7691172049650542,1852.0342295558505,36.0,0.7710311022180405,1856.6428941410416,35.0,nonessential
833,HNEAP_RS04380,WP_012823746.1,502585973.0,936559,937788,1229.0,+,alanine--glyoxylate aminotransferase family protein,0.552,31,0.9999998545628734,2407.9996497873994,87.0,0.999999469557105,2407.9987226935086,83.0,nonessential
834,HNEAP_RS04385,WP_012823747.1,502585974.0,937757,939031,1274.0,+,allantoate amidohydrolase,0.5678,24,0.999615009042573,2407.072941774516,75.0,0.9995888939491392,2407.0100566295273,73.0,nonessential
835,HNEAP_RS04390,WP_012823748.1,502585975.0,939028,939504,476.0,+,regulator of ribonuclease activity A,0.5933,11,0.9983611940904565,2404.0537553698196,32.0,0.9989951665326856,2405.580361010707,32.0,nonessential
836,HNEAP_RS04395,WP_012823749.1,502585976.0,939591,940622,1031.0,-,adenosine deaminase,0.5165,27,0.9999203313540677,2407.808157900595,66.0,0.999942046294415,2407.8604474769513,65.0,nonessential
837,HNEAP_RS04400,WP_012823750.1,502585977.0,940743,941813,1070.0,-,BMP family ABC transporter substrate-binding protein,0.4902,35,0.9880993772534571,2379.3433004263247,57.0,0.9933014584966029,2391.86991205982,57.0,nonessential
838,HNEAP_RS04405,WP_012823751.1,502585978.0,941852,942766,914.0,-,hypothetical protein,0.5224,36,0.3909400302377029,941.3835928123887,34.0,0.463565528254642,1116.2657920371778,34.0,nonessential
839,HNEAP_RS04410,WP_012823753.1,502585980.0,943311,944348,1037.0,-,formamidase,0.5732,27,0.9999999999999806,2407.999999999953,96.0,0.9999999999999789,2407.999999999949,94.0,nonessential
840,HNEAP_RS04415,WP_012823754.1,502585981.0,944496,945218,722.0,-,amino acid ABC transporter ATP-binding protein,0.5795,10,0.965162553118025,2324.1114279082044,38.0,0.9846859991835804,2371.1238860340613,39.0,nonessential
841,HNEAP_RS04440,WP_012823757.1,502585984.0,947500,948885,1385.0,-,oxygen-independent coproporphyrinogen III oxidase,0.562,23,0.8784893890720626,2115.402448885527,63.0,0.8980642592906231,2162.5387363718205,62.0,nonessential
842,HNEAP_RS04445,WP_012823758.1,502585985.0,949150,949764,614.0,+,hypothetical protein,0.5691,13,0.9999979692884408,2407.9951100465655,49.0,0.9999980509283211,2407.995306635397,48.0,nonessential
843,HNEAP_RS04450,WP_012823759.1,502585986.0,949854,950783,929.0,+,ABC transporter ATP-binding protein,0.5409,14,0.7847841774267806,1889.7602992436878,41.0,0.8733495823640073,2103.0257943325296,42.0,nonessential
844,HNEAP_RS04455,WP_041600710.1,753845093.0,950837,951610,773.0,+,ABC transporter permease,0.5413,23,0.49814761855531586,1199.5394654812005,30.0,0.4923542385605656,1185.5890064538419,29.0,nonessential
845,HNEAP_RS04460,WP_012823761.1,502585988.0,951612,953570,1958.0,+,collagenase-like protease,0.5906,28,0.9999871168950638,2407.9689774833137,116.0,0.9999784795332662,2407.9481787161053,112.0,nonessential
846,HNEAP_RS04465,WP_012823762.1,502585989.0,953716,954504,788.0,+,EAL domain-containing protein,0.4956,21,0.3826953852724043,921.5304877359496,29.0,0.4496978430780892,1082.8724061320388,29.0,nonessential
847,HNEAP_RS04470,WP_012823763.1,502585990.0,954677,955054,377.0,+,DUF202 domain-containing protein,0.5635,6,0.11539174582940338,277.86332395720336,10.0,0.21400443799378166,515.3226866890262,11.0,nonessential
848,HNEAP_RS12490,WP_012823764.1,502585991.0,955144,955875,731.0,+,peptidase S24/S26A/S26B  conserved region,0.612,12,0.9722072118952101,2341.074966243666,39.0,0.9881458494764819,2379.4552055393683,40.0,nonessential
849,HNEAP_RS04480,WP_012823765.1,502585992.0,955880,957199,1319.0,+,translesion error-prone DNA polymerase V subunit UmuC,0.5621,32,0.46083664172659455,1109.6946332776397,51.0,0.43601086021956875,1049.9141514087216,49.0,nonessential
850,HNEAP_RS04485,WP_012823766.1,502585993.0,957314,958975,1661.0,-,cation acetate symporter,0.5674,36,0.4865041698658774,1171.5020410370328,65.0,0.384602036596895,926.1217041253232,61.0,nonessential
851,HNEAP_RS04490,WP_012823767.1,502585994.0,958972,959280,308.0,-,DUF485 domain-containing protein,0.5113,6,0.5498483797517544,1324.0348984422246,12.0,0.4761486706714583,1146.5659989768715,11.0,nonessential
852,HNEAP_RS04495,WP_049772569.1,908628536.0,959498,960466,968.0,-,MoxR family ATPase,0.5831,16,0.9994108484506117,2406.581323069073,59.0,0.9992186153702227,2406.1184258114963,57.0,nonessential
853,HNEAP_RS04500,WP_012823769.1,502585996.0,960484,962262,1778.0,-,hypothetical protein,0.5767,32,0.9986801203065779,2404.82172969824,96.0,0.9988935371504701,2405.3356374583323,94.0,nonessential
854,HNEAP_RS04505,WP_012823770.1,502585997.0,962275,962697,422.0,-,hypothetical protein,0.5485,8,0.980619692983789,2361.332220704964,25.0,0.9922474724606263,2389.3319136851883,26.0,nonessential
855,HNEAP_RS04510,WP_012823771.1,502585998.0,962753,963955,1202.0,-,UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase,0.5752,26,3.6657752034555087e-20,8.827186689920865e-17,1.0,1.5808239876982984e-19,3.8066241623775024e-16,1.0,essential
856,HNEAP_RS04515,WP_012823772.1,502585999.0,963958,965178,1220.0,-,UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase,0.6052,21,3.4895600175768404e-22,8.402860522325032e-19,0.0,1.5875079849007437e-21,3.822719227640991e-18,0.0,essential
857,HNEAP_RS04520,WP_012823773.1,502586000.0,965230,966579,1349.0,-,Xaa-Pro aminopeptidase,0.5741,21,0.9999894219240286,2407.9745279930607,86.0,0.9999980673285744,2407.995346127207,87.0,nonessential
858,HNEAP_RS04525,WP_012823774.1,502586001.0,966596,967156,560.0,-,hypothetical protein,0.5437,10,0.9999911505245404,2407.9786904630932,44.0,0.9999578296823343,2407.898453875061,41.0,nonessential
859,HNEAP_RS04530,WP_012823775.1,502586002.0,967367,967639,272.0,+,hypothetical protein,0.5128,5,0.001236736605417641,2.9780617458456793,2.0,0.0016362166270073367,3.9400096378336666,2.0,nonessential
860,HNEAP_RS04535,WP_012823776.1,502586003.0,967645,967950,305.0,+,cell division protein ZapA,0.5098,8,0.04029701196972407,97.03520482309557,6.0,0.0005524584382055235,1.3303199191989008,2.0,nonessential
861,HNEAP_RS04540,WP_012823777.1,502586004.0,968042,968488,446.0,-,hypothetical protein,0.5034,12,0.8758135965557377,2108.959140506216,22.0,0.8562168074395561,2061.770072314451,21.0,nonessential
862,HNEAP_RS04545,WP_012823778.1,502586005.0,968702,969235,533.0,-,type 3 dihydrofolate reductase,0.5243,18,0.14989103251117622,360.93760628691234,16.0,0.00727726392626676,17.52365153445036,10.0,nonessential
863,HNEAP_RS04550,WP_012823779.1,502586006.0,969232,969651,419.0,-,phosphate starvation-inducible protein PsiE,0.4738,15,7.173135528682411e-06,0.017272910353067248,2.0,1.2777809356089602e-06,0.003076896492946376,1.0,essential
864,HNEAP_RS04555,WP_012823780.1,502586007.0,969681,970475,794.0,-,thymidylate synthase,0.5459,18,3.6671073057449755e-13,8.830394392233901e-10,1.0,9.531143013784014e-13,2.2950992377191905e-09,1.0,essential
865,HNEAP_RS04560,WP_012823781.1,502586008.0,970472,971299,827.0,-,prolipoprotein diacylglyceryl transferase,0.5302,19,1.7628012889328287e-12,4.2448255037502515e-09,2.0,4.62839485435331e-12,1.1145174809282769e-08,2.0,essential
866,HNEAP_RS04565,WP_012823782.1,502586009.0,971679,972320,641.0,-,microcompartments protein,0.5296,12,0.04784986288744197,115.22246983296026,17.0,0.06450781982002643,155.33483012662364,17.0,nonessential
867,HNEAP_RS04570,WP_012823783.1,502586011.0,972405,972707,302.0,-,hypothetical protein,0.495,9,0.34446489779960454,829.4714739014478,10.0,0.5035740381746335,1212.6062839245176,11.0,nonessential
868,HNEAP_RS04575,WP_012823784.1,502586012.0,972739,973542,803.0,-,CbbQ/NirQ/NorQ/GpvN family protein,0.505,19,0.8456409814136113,2036.303483243976,37.0,0.8024420039588308,1932.2803455328647,35.0,nonessential
869,HNEAP_RS04580,WP_012823785.1,502586013.0,973595,973930,335.0,-,nitrogen regulatory protein P-II,0.4732,5,0.9219562272510589,2220.07059522055,18.0,0.9380078640834705,2258.722936712997,18.0,nonessential
870,HNEAP_RS04585,WP_012823786.1,502586014.0,973927,977067,3140.0,-,DUF2309 domain-containing protein,0.5142,85,0.6430812509726719,1548.539652342194,128.0,0.6013551434316037,1448.0631853833017,123.0,nonessential
871,HNEAP_RS04590,WP_012823787.1,502586015.0,977072,977818,746.0,-,hypothetical protein,0.5408,15,0.5034753475103744,1212.3686368049814,29.0,0.41930876164243375,1009.6954980349805,27.0,nonessential
872,HNEAP_RS04595,WP_012823788.1,502586016.0,977820,979499,1679.0,-,oxidoreductase,0.5179,42,0.9999945856092214,2407.986962147005,104.0,0.9999985185401224,2407.9964326446147,104.0,nonessential
873,HNEAP_RS04600,WP_012823789.1,502586017.0,979659,982025,2366.0,-,VWA domain-containing protein,0.5091,64,0.13580891541386833,327.02786831659495,83.0,0.1526935754778031,367.68612975054987,81.0,nonessential
874,HNEAP_RS04605,WP_041600361.1,753844744.0,982133,982360,227.0,+,hypothetical protein,0.5482,3,0.707306580032526,1703.1942447183226,10.0,0.8317024404123937,2002.739476513044,11.0,nonessential
875,HNEAP_RS04610,WP_049772467.1,908628434.0,982347,983027,680.0,-,ParA family protein,0.5169,18,0.9987171504557795,2404.910898297517,43.0,0.9992900301787148,2406.290392670345,43.0,nonessential
876,HNEAP_RS04615,WP_012823792.1,502586020.0,983002,983283,281.0,-,hypothetical protein,0.4397,9,0.06862858128945218,165.25762374500084,6.0,0.08228429512463324,198.14058266011685,6.0,nonessential
877,HNEAP_RS04620,WP_012823793.1,502586021.0,983594,983926,332.0,-,major carboxysome shell protein 1B,0.5495,4,0.5532552141346785,1332.2385556363058,13.0,0.5976594617798577,1439.1639839658974,13.0,nonessential
878,HNEAP_RS04625,WP_012823794.1,502586022.0,984038,984334,296.0,-,major carboxysome shell protein 1A,0.5387,7,0.4889548755050869,1177.4033402162493,11.0,0.6462082307679912,1556.0694196893228,12.0,nonessential
879,HNEAP_RS04630,WP_012823795.1,502586023.0,984409,984705,296.0,-,major carboxysome shell protein 1C,0.5589,4,0.7983325184465321,1922.3847044192491,14.0,0.827963276919637,1993.735570822486,14.0,nonessential
880,HNEAP_RS04635,WP_012823796.1,502586024.0,984757,985002,245.0,-,carboxysome peptide B,0.5122,7,0.24076620675341506,579.7650258622235,7.0,0.16501016603583665,397.3444798142947,6.0,nonessential
881,HNEAP_RS04640,WP_012823797.1,502586025.0,985002,985253,251.0,-,carboxysome peptide A,0.496,8,0.1274735291743967,306.95625825194725,6.0,0.07696193655373562,185.32434322139537,5.0,nonessential
882,HNEAP_RS04645,WP_012823798.1,502586026.0,985250,986794,1544.0,-,carboxysome shell carbonic anhydrase,0.479,61,0.016536694253427322,39.82035976225299,45.0,0.020494709409854494,49.35126025892962,44.0,nonessential
883,HNEAP_RS04650,WP_081441107.1,1174219926.0,986815,989436,2621.0,-,hypothetical protein,0.5297,72,0.48522070333609646,1168.4114536333202,103.0,0.6098174078665347,1468.4403181426155,103.0,nonessential
884,HNEAP_RS04655,WP_012823800.1,502586028.0,989489,989821,332.0,-,ribulose bisphosphate carboxylase small subunit,0.4805,11,0.9743362638457044,2346.2017233404563,20.0,0.965935614585106,2325.9729599209354,19.0,nonessential
885,HNEAP_RS04660,WP_012823801.1,502586029.0,989858,991279,1421.0,-,ribulose bisphosphate carboxylase large chain,0.5316,40,0.9999999999704474,2407.9999999288375,110.0,0.9999999999777687,2407.999999946467,108.0,nonessential
886,HNEAP_RS04665,WP_012823802.1,502586030.0,992209,994716,2507.0,+,copper-translocating P-type ATPase,0.5482,57,0.9999243043636121,2407.817724907578,138.0,0.9999096443884311,2407.782423687342,134.0,nonessential
887,HNEAP_RS04670,WP_012823803.1,502586031.0,994728,995123,395.0,+,DUF302 domain-containing protein,0.5354,7,0.49770285116279944,1198.468465600021,15.0,0.5466296929444857,1316.2843006103217,15.0,nonessential
888,HNEAP_RS04675,WP_012823804.1,502586032.0,995153,995359,206.0,+,heavy metal transport/detoxification protein,0.5314,6,0.991442771881,2387.3941946894483,15.0,0.985748184422053,2373.6816280883036,14.0,nonessential
889,HNEAP_RS04680,WP_012823805.1,502586033.0,995660,996082,422.0,-,hypothetical protein,0.4161,27,0.027414437333495266,66.0139650990566,9.0,0.017565463406574965,42.29763588303251,8.0,nonessential
890,HNEAP_RS04685,WP_012823806.1,502586034.0,996128,997321,1193.0,-,NnrS family protein,0.4665,56,0.4588634801520677,1104.943260206179,46.0,0.4837329524335404,1164.8289494599653,45.0,nonessential
891,HNEAP_RS04690,WP_081441108.1,1174219927.0,997318,997731,413.0,-,hypothetical protein,0.4396,12,0.9574858206485072,2305.6258561216055,23.0,0.9483750897530163,2283.687216125263,22.0,nonessential
892,HNEAP_RS04695,WP_012823808.1,502586036.0,997874,998326,452.0,+,Rrf2 family transcriptional regulator,0.4525,14,0.20679449004353392,497.9611320248297,14.0,0.24504069551512736,590.0579948004266,14.0,nonessential
893,HNEAP_RS04705,WP_041600363.1,753844746.0,998963,999373,410.0,+,hypothetical protein,0.5036,6,0.43745751759970464,1053.3977023800887,15.0,0.4868580991380198,1172.3543027243518,15.0,nonessential
894,HNEAP_RS04710,WP_041600364.1,753844747.0,999431,999736,305.0,+,hypothetical protein,0.4869,11,0.9368593895692753,2255.957410082815,17.0,0.9499288826545899,2287.4287494322525,17.0,nonessential
895,HNEAP_RS04715,WP_012823810.1,502586038.0,999733,1000269,536.0,+,hypothetical protein,0.5289,13,0.9745733383612948,2346.7725987739977,30.0,0.9559346364274427,2301.890604517282,28.0,nonessential
896,HNEAP_RS04720,WP_041600365.1,753844748.0,1000428,1001315,887.0,+,hypothetical protein,0.5124,25,0.8598685123935413,2070.5633778436477,41.0,0.8653034090868507,2083.6506090811363,40.0,nonessential
897,HNEAP_RS04725,WP_012823812.1,502586040.0,1001408,1001965,557.0,-,hypothetical protein,0.5072,11,0.9902189972445434,2384.4473453648607,33.0,0.9892767308345457,2382.1783678495863,32.0,nonessential
898,HNEAP_RS04730,WP_012823813.1,502586041.0,1001965,1002645,680.0,-,hypothetical protein,0.4714,19,0.6971067314678483,1678.6330093745787,29.0,0.6868884344386439,1654.0273501282545,28.0,nonessential
899,HNEAP_RS04735,WP_012823814.1,502586042.0,1002642,1003118,476.0,-,hypothetical protein,0.499,11,0.9732104979725632,2343.4908791179323,27.0,0.9688543626090048,2333.0013051624837,26.0,nonessential
900,HNEAP_RS12495,WP_012823815.1,502586043.0,1003452,1004522,1070.0,+,ATPase-like protein,0.4043,57,0.02590848217458662,62.38762507640458,30.0,0.03985458244546833,95.96983452868774,30.0,nonessential
901,HNEAP_RS04745,WP_012823817.1,502586045.0,1004956,1005984,1028.0,-,IS30 family transposase,0.5734,20,0.9994151338734134,2406.5916423671797,62.0,0.9997292208465721,2407.3479637985456,62.0,nonessential
902,HNEAP_RS12205,WP_081441109.1,1174219928.0,1007503,1011924,4421.0,+,RHS repeat protein,0.5599,146,0.9999999999999999,2407.9999999999995,343.0,0.9999999999999999,2407.9999999999995,326.0,nonessential
903,HNEAP_RS04755,WP_012823820.1,502586048.0,1011928,1012176,248.0,+,hypothetical protein,0.4819,6,0.0693285803632403,166.94322151468265,5.0,0.003550335960260025,8.54920899230614,2.0,nonessential
904,HNEAP_RS04760,WP_012823821.1,502586049.0,1012572,1015403,2831.0,+,conjugative relaxase,0.523,57,0.9999999999999999,2407.9999999999995,243.0,0.9999999999999999,2407.9999999999995,232.0,nonessential
905,HNEAP_RS04765,WP_049772570.1,908628537.0,1015919,1016581,662.0,-,phosphate acetyltransferase,0.5158,23,0.962089195281953,2316.710782238943,35.0,0.9739822225958673,2345.3491920108486,35.0,nonessential
906,HNEAP_RS04770,WP_012823825.1,502586053.0,1016601,1017401,800.0,-,metallophosphoesterase,0.5106,19,0.9992141844452985,2406.107756144279,50.0,0.9987995015628911,2405.1091997634417,48.0,nonessential
907,HNEAP_RS04780,WP_012823828.1,502586056.0,1020949,1022808,1859.0,+,beta-ketoacyl synthase,0.4887,62,0.06917754896332023,166.57953790367512,61.0,0.06979635116648522,168.06961360889642,59.0,nonessential
908,HNEAP_RS04795,WP_012823829.1,502586057.0,1025227,1026138,911.0,+,TauD/TfdA family dioxygenase,0.4221,45,0.7731504846387924,1861.7463670102122,40.0,0.8262197554019092,1989.5371710077973,40.0,nonessential
909,HNEAP_RS04800,WP_012823830.1,502586058.0,1026140,1026679,539.0,+,hypothetical protein,0.413,24,0.09192512545074702,221.35570208539883,15.0,0.11660393506449872,280.7822756353129,15.0,nonessential
910,HNEAP_RS04805,WP_012823831.1,502586059.0,1026718,1027086,368.0,+,phosphopantetheine-binding protein,0.4173,11,0.9004876887763207,2168.37435457338,19.0,0.8775861842329347,2113.2275316329064,18.0,nonessential
911,HNEAP_RS04810,WP_012823832.1,502586061.0,1027089,1033493,6404.0,+,type I polyketide synthase,0.4748,246,0.9459150865917306,2277.763528512887,279.0,0.9726176964960284,2342.0634131624365,276.0,nonessential
912,HNEAP_RS04815,WP_012823833.1,502586062.0,1033490,1035082,1592.0,+,AMP-dependent ligase,0.4639,70,0.2780363616082619,669.5115587526947,58.0,0.31643006342724256,761.9635927328001,57.0,nonessential
913,HNEAP_RS04820,WP_012823834.1,502586063.0,1035118,1036296,1178.0,+,transcription factor jumonji jmjC domain-containing protein,0.4377,66,0.6660054115016354,1603.741030895938,49.0,0.7398797974818545,1781.6305523363058,49.0,nonessential
914,HNEAP_RS12505,WP_012823835.1,502586064.0,1037250,1038083,833.0,+,alpha/beta hydrolase,0.4604,34,0.1617713464241752,389.5454021894139,27.0,0.20788582879324521,500.5890757341345,27.0,nonessential
915,HNEAP_RS12215,WP_012823836.1,502586065.0,1038328,1039095,767.0,-,phosphopantetheinyl transferase component of siderophore synthetase-like protein,0.4492,32,0.04339927361168011,104.5054508569257,21.0,0.08943876777789156,215.36855280916288,22.0,nonessential
916,HNEAP_RS04835,WP_012823837.1,502586066.0,1039450,1040163,713.0,-,LuxR family transcriptional regulator,0.3908,39,5.476012170459448e-05,0.1318623730646635,10.0,9.805205502568173e-05,0.2361093485018416,10.0,nonessential
917,HNEAP_RS12510,WP_012823838.1,502586067.0,1040274,1040714,440.0,+,DUF4902 domain-containing protein,0.458,15,0.03664787834518014,88.24809105519378,10.0,0.0248682015967771,59.88262944503926,9.0,nonessential
918,HNEAP_RS12515,WP_012823839.1,502586068.0,1040904,1041470,566.0,+,N-acylhomoserine lactone synthase,0.4832,21,0.5163575774570319,1243.389046516533,22.0,0.4883323044995912,1175.9041892350156,21.0,nonessential
919,HNEAP_RS04850,WP_012823841.1,502586076.0,1041987,1042673,686.0,-,hypothetical protein,0.4512,28,0.12926789947497572,311.27710193574154,21.0,0.11765093383367609,283.303448671492,20.0,nonessential
920,HNEAP_RS04855,WP_012823842.1,502586077.0,1042673,1043038,365.0,-,hypothetical protein,0.4344,18,0.08395930213356614,202.17399953762728,9.0,0.057052494582606535,137.38240695491655,8.0,nonessential
921,HNEAP_RS04860,WP_012823843.1,502586078.0,1043195,1044241,1046.0,-,site-specific integrase,0.5043,22,0.9835443545287368,2368.374805705198,55.0,0.9275919135213477,2233.641327759405,49.0,nonessential
922,HNEAP_RS04865,WP_012823844.1,502586079.0,1045010,1046305,1295.0,-,phosphopyruvate hydratase,0.5594,24,0.7252261007344202,1746.3444505684838,55.0,0.752918077056099,1813.0267295510864,54.0,nonessential
923,HNEAP_RS04870,WP_012823845.1,502586080.0,1046396,1048909,2513.0,-,plasma-membrane proton-efflux P-type ATPase,0.5994,30,0.9999999635565637,2407.9999122442055,156.0,0.999999823607072,2407.9995752458294,149.0,nonessential
924,HNEAP_RS04875,WP_012823846.1,502586081.0,1048970,1049767,797.0,-,polyphosphate kinase 2,0.5664,15,0.9871433707627023,2377.0412367965873,44.0,0.9878282708741883,2378.6904762650456,43.0,nonessential
925,HNEAP_RS04880,WP_049772472.1,908628439.0,1050077,1050610,533.0,-,hypothetical protein,0.5843,12,0.10046228076115209,241.91317207285422,15.0,0.08213677811533168,197.7853617017187,14.0,nonessential
926,HNEAP_RS04885,WP_012823847.1,502586082.0,1050758,1050964,206.0,+,XRE family transcriptional regulator,0.4251,11,0.8793835200901781,2117.5555163771487,11.0,0.8973052065642245,2160.7109374066526,11.0,nonessential
927,HNEAP_RS04895,WP_012823848.1,502586083.0,1051531,1051881,350.0,-,hypothetical protein,0.5043,10,0.6823385022266963,1643.0711133618847,15.0,0.7231686058488722,1741.3900028840842,15.0,nonessential
928,HNEAP_RS04900,WP_012823849.1,502586084.0,1051973,1052752,779.0,-,M48 family peptidase,0.4936,23,0.8022796914898086,1931.8894971074592,35.0,0.8021342784437466,1931.539342492542,34.0,nonessential
929,HNEAP_RS04905,WP_012823850.1,502586085.0,1052774,1054294,1520.0,-,leucyl aminopeptidase,0.5648,23,0.46470431308090315,1119.0079858988147,59.0,0.11272863234557304,271.45054668813987,49.0,nonessential
930,HNEAP_RS04910,WP_012823851.1,502586086.0,1054432,1054716,284.0,+,hypothetical protein,0.5298,5,0.4248999812684666,1023.1591548944676,10.0,0.46574713071796847,1121.5190907688682,10.0,nonessential
931,HNEAP_RS04915,WP_081441110.1,1174219929.0,1054783,1055568,785.0,-,NlpC/P60 family protein,0.5229,16,0.4633587007574972,1115.7677514240531,30.0,0.4581542818878701,1103.2355107859912,29.0,nonessential
932,HNEAP_RS04920,WP_012823853.1,502586088.0,1055462,1057717,2255.0,-,bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL,0.5541,41,0.9999999999999972,2407.999999999993,170.0,0.9999999999999867,2407.9999999999677,164.0,nonessential
933,HNEAP_RS04925,WP_012823854.1,502586089.0,1057975,1059669,1694.0,+,ABC transporter ATP-binding protein,0.5522,24,0.9986440018734779,2404.7347565113346,92.0,0.9975429044084512,2402.0833138155504,88.0,nonessential
934,HNEAP_RS04930,WP_012823855.1,502586090.0,1059721,1060938,1217.0,-,beta-ketoacyl-[acyl-carrier-protein] synthase I,0.5361,23,3.9403459293096605e-22,9.488352997777662e-19,0.0,1.7859187584777802e-21,4.300492370414495e-18,0.0,essential
935,HNEAP_RS04935,WP_012823856.1,502586091.0,1060945,1061463,518.0,-,bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase,0.5067,8,7.753030315808853e-10,1.866929700046772e-06,0.0,1.4751241124760017e-09,3.5520988628422122e-06,0.0,essential
936,HNEAP_RS04940,WP_012823857.1,502586092.0,1061742,1062128,386.0,-,DUF423 domain-containing protein,0.5194,11,0.9073230059894168,2184.833798422516,20.0,0.9267801247716827,2231.686540450212,20.0,nonessential
937,HNEAP_RS04945,WP_012823858.1,502586093.0,1062161,1062733,572.0,-,outer membrane protein assembly factor BamE,0.541,18,0.8901882527639692,2143.573312655638,28.0,0.8810544768353048,2121.579180219414,27.0,nonessential
938,HNEAP_RS04950,WP_012823859.1,502586094.0,1062913,1063332,419.0,+,ferric iron uptake transcriptional regulator,0.4714,13,0.6907320333613336,1663.2827363340914,18.0,0.8071499922850202,1943.6171814223285,19.0,nonessential
939,HNEAP_RS04955,WP_012823860.1,502586095.0,1063593,1064225,632.0,-,DUF1134 domain-containing protein,0.5197,21,0.9013223610497565,2170.3842454078135,31.0,0.9265573306797752,2231.150052276899,31.0,nonessential
940,HNEAP_RS04960,WP_012823861.1,502586096.0,1064665,1064964,299.0,+,hypothetical protein,0.49,7,0.24897326897571773,599.5276316935283,9.0,0.28296826898431726,681.387591714236,9.0,nonessential
941,HNEAP_RS04965,WP_012823862.1,502586097.0,1065059,1065625,566.0,+,dCTP deaminase,0.5009,16,2.6852512572444497e-07,0.0006466085027444635,3.0,4.951194278310605e-07,0.0011922475822171937,3.0,essential
942,HNEAP_RS04970,WP_012823863.1,502586098.0,1065693,1066349,656.0,-,HAD-IB family hydrolase,0.5114,12,8.151350707986976e-11,1.9628452504832636e-07,1.0,1.7853018269864165e-10,4.299006799383291e-07,1.0,essential
943,HNEAP_RS04975,WP_012823864.1,502586099.0,1066591,1067133,542.0,+,RNA pyrophosphohydrolase,0.5341,12,0.6789400963106712,1634.8877519160962,23.0,0.4812803948286517,1158.9231907473934,20.0,nonessential
944,HNEAP_RS04980,WP_012823865.1,502586100.0,1067123,1069408,2285.0,+,phosphoenolpyruvate-protein phosphotransferase PtsP,0.5621,46,0.9281511942640464,2234.9880757878236,104.0,0.9270725372275248,2232.39066964388,101.0,nonessential
945,HNEAP_RS05005,WP_041600370.1,753844753.0,1070192,1070911,719.0,-,tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB,0.5736,16,0.00013021593506931076,0.3135599716469003,11.0,2.8126873247831255e-05,0.06772951078077766,9.0,nonessential
946,HNEAP_RS05010,WP_012823867.1,502586102.0,1070924,1072567,1643.0,-,glucose-6-phosphate isomerase,0.5791,29,8.736385941624471e-28,2.1037217347431728e-24,1.0,6.513394721193555e-27,1.568425448863408e-23,1.0,essential
947,HNEAP_RS05015,WP_012823868.1,502586103.0,1072662,1074176,1514.0,-,glucose-6-phosphate dehydrogenase,0.5644,25,0.9999450849161594,2407.867764478112,91.0,0.9992866914682023,2406.282353055431,83.0,nonessential
948,HNEAP_RS05020,WP_012823869.1,502586104.0,1074260,1075174,914.0,-,6-phosphogluconate dehydrogenase (decarboxylating),0.5738,10,0.9999990664948415,2407.9977521195783,67.0,0.9999996750165699,2407.9992174399003,67.0,nonessential
949,HNEAP_RS05025,WP_012823870.1,502586105.0,1075470,1078286,2816.0,+,phosphoenolpyruvate carboxylase,0.5321,67,2.9682031198196953e-50,7.147433112525826e-47,0.0,9.798524372766056e-49,2.3594846689620664e-45,0.0,essential
950,HNEAP_RS05030,WP_012823871.1,502586106.0,1078427,1079377,950.0,+,cation transporter,0.5804,9,0.7409300003382943,1784.1594408146125,41.0,0.7508893232219519,1808.1414903184602,40.0,nonessential
951,HNEAP_RS05035,WP_012823872.1,502586107.0,1079417,1080931,1514.0,+,glycerol kinase,0.5776,38,0.5813241021633015,1399.8284380092302,61.0,0.6236117856739509,1501.6571799028738,60.0,nonessential
952,HNEAP_RS05040,WP_012823873.1,502586108.0,1080955,1082736,1781.0,+,ABC transporter ATP-binding protein/permease,0.5623,27,0.9996955375114277,2407.266854327518,100.0,0.9996325970455486,2407.115293685681,97.0,nonessential
953,HNEAP_RS05045,WP_012823874.1,502586109.0,1082825,1083613,788.0,+,hypothetical protein,0.5817,16,0.527567270649925,1270.3819877250194,31.0,0.4496978430780892,1082.8724061320388,29.0,nonessential
954,HNEAP_RS05050,WP_012823875.1,502586110.0,1083682,1085103,1421.0,+,replicative DNA helicase,0.5731,19,1.8145138689115478e-22,4.369349396339008e-19,2.0,9.953796507014852e-22,2.3968741988891764e-18,2.0,essential
955,HNEAP_RS05055,WP_012823876.1,502586111.0,1085100,1086236,1136.0,+,alanine racemase,0.6227,21,0.9548123531973534,2299.188146499227,56.0,0.9091060210509507,2189.1272986906893,52.0,nonessential
956,HNEAP_RS05060,WP_012823877.1,502586112.0,1086278,1087012,734.0,+,glutamine amidotransferase,0.5687,12,0.02855797773987679,68.76761039762332,19.0,0.014526829346106903,34.98060506542542,17.0,nonessential
957,HNEAP_RS05065,WP_012823879.1,502586114.0,1087395,1087694,299.0,-,hypothetical protein,0.4867,9,0.35727481530397903,860.3177552519815,10.0,0.28296826898431726,681.387591714236,9.0,nonessential
958,HNEAP_RS05070,WP_012823880.1,502586115.0,1087881,1088345,464.0,-,hypothetical protein,0.3247,36,6.9058588628186554e-09,1.6629308141667323e-05,0.0,2.40545722572343e-07,0.0005792340999542019,1.0,essential
959,HNEAP_RS05075,WP_012823881.1,502586116.0,1088407,1089603,1196.0,-,ribonucleotide-diphosphate reductase subunit beta,0.5606,21,9.22316762306108e-22,2.220938763633108e-18,0.0,4.0726975807171305e-21,9.80705577436685e-18,0.0,essential
960,HNEAP_RS05080,WP_012823882.1,502586117.0,1089651,1092524,2873.0,-,ribonucleoside-diphosphate reductase subunit alpha,0.5776,51,2.951098615799035e-51,7.106245466844077e-48,0.0,1.045660847668061e-49,2.5179513211846907e-46,0.0,essential
961,HNEAP_RS05085,WP_012823883.1,502586118.0,1093056,1094063,1007.0,+,NAD-dependent epimerase,0.5585,28,1.945323611705316e-18,4.6843392569864015e-15,0.0,6.79307384894849e-18,1.6357721828267965e-14,0.0,essential
962,HNEAP_RS05090,WP_012823884.1,502586119.0,1094055,1094903,848.0,-,hypothetical protein,0.5477,14,0.9360679448801148,2254.0516112713162,42.0,0.9161350711494185,2206.0532513278,40.0,nonessential
963,HNEAP_RS05095,WP_012823885.1,502586120.0,1094938,1095777,839.0,-,metal ABC transporter permease,0.5905,14,4.998193777995113e-09,1.2035650617412233e-05,6.0,5.817319796352179e-08,0.00014008106069616046,7.0,essential
964,HNEAP_RS05100,WP_012823886.1,502586121.0,1095764,1096627,863.0,-,ABC transporter ATP-binding protein,0.5891,13,0.001480216477158382,3.5643612769973836,18.0,0.00011381653863723694,0.27407022503846656,14.0,nonessential
965,HNEAP_RS05105,WP_012823887.1,502586122.0,1096634,1097515,881.0,-,ABC transporter substrate-binding protein,0.5454,17,1.9475087005405325e-10,4.689600950901602e-07,5.0,7.592238182638168e-12,1.828210954379271e-08,3.0,essential
966,HNEAP_RS05110,WP_041600735.1,753845118.0,1097727,1098263,536.0,+,SMC-Scp complex subunit ScpB,0.5885,13,0.9999692200327187,2407.9258818387866,41.0,0.9999846330620242,2407.962996413354,41.0,nonessential
967,HNEAP_RS05115,WP_041600371.1,753844754.0,1098628,1099824,1196.0,+,hypothetical protein,0.5731,21,0.08879365845775787,213.81512956628094,38.0,0.07187285789622337,173.06984181410587,36.0,nonessential
968,HNEAP_RS05120,WP_012823890.1,502586125.0,1099851,1100723,872.0,+,4-hydroxybenzoate octaprenyltransferase,0.5819,18,3.158528956220717e-13,7.605737726579487e-10,2.0,8.768759371486101e-13,2.111517256653853e-09,2.0,essential
969,HNEAP_RS05125,WP_012823891.1,502586126.0,1100714,1103890,3176.0,-,AcrB/AcrD/AcrF family protein,0.5656,56,0.9992867900842611,2406.2825905229006,162.0,0.9979719647165549,2403.116491037464,154.0,nonessential
970,HNEAP_RS05130,WP_012823892.1,502586127.0,1103883,1105196,1313.0,-,efflux RND transporter periplasmic adaptor subunit,0.5769,19,0.9259612849606403,2229.714774185222,62.0,0.9204114669547107,2216.3508124269433,60.0,nonessential
971,HNEAP_RS05135,WP_012823893.1,502586128.0,1105193,1106779,1586.0,-,TolC family protein,0.5696,32,0.9999999994545111,2407.9999986864627,115.0,0.9999999996280473,2407.999999104338,113.0,nonessential
972,HNEAP_RS05140,WP_012823894.1,502586129.0,1106922,1107368,446.0,-,hypothetical protein,0.566,15,0.9874087554550764,2377.680283135824,27.0,0.9745507092411799,2346.7181078527615,25.0,nonessential
973,HNEAP_RS05145,WP_012823895.1,502586130.0,1107420,1107776,356.0,-,hypothetical protein,0.6359,11,0.999997071184555,2407.9929474124087,33.0,0.9999894490267882,2407.974593256506,31.0,nonessential
974,HNEAP_RS05150,WP_049772473.1,908628440.0,1108142,1108789,647.0,-,nitroreductase family protein,0.5216,12,0.7220977144144459,1738.811296309986,28.0,0.7731081710325164,1861.6444758462994,28.0,nonessential
975,HNEAP_RS05155,WP_012823897.1,502586132.0,1108859,1109710,851.0,-,pirin family protein,0.5657,14,0.8794488375049024,2117.712800711805,40.0,0.9127787641723354,2197.9712641269834,40.0,nonessential
976,HNEAP_RS05160,WP_012823898.1,502586134.0,1109764,1110441,677.0,-,polyisoprenoid-binding protein,0.5044,16,0.9998004946585751,2407.5195911378487,46.0,0.9998086634743194,2407.5392616461613,45.0,nonessential
977,HNEAP_RS05165,WP_012823899.1,502586135.0,1110551,1111435,884.0,+,LysR family transcriptional regulator,0.5605,21,0.011088205303386197,26.700398370553962,22.0,0.017203840599982177,41.42684816475708,22.0,nonessential
978,HNEAP_RS05170,WP_012823900.1,502586136.0,1111472,1112185,713.0,-,rhodanese-like domain-containing protein,0.5014,13,0.9871521169634111,2377.062297647894,40.0,0.956241918972899,2302.6305408867406,36.0,nonessential
979,HNEAP_RS05175,WP_012823901.1,502586137.0,1112352,1112726,374.0,+,fluoride efflux transporter CrcB,0.488,12,0.2758500223599333,664.2468538427194,12.0,0.3161420620810513,761.2700854911715,12.0,nonessential
980,HNEAP_RS05180,WP_012823902.1,502586138.0,1112739,1113860,1121.0,+,tRNA epoxyqueuosine(34) reductase QueG,0.557,20,0.4488769487770969,1080.8956926552494,43.0,0.5309576956113509,1278.546131032133,43.0,nonessential
981,HNEAP_RS05185,WP_012823903.1,502586139.0,1113814,1115205,1391.0,-,hypothetical protein,0.5165,31,0.1138433337522739,274.1347476754756,46.0,0.16305356725466713,392.63298994923844,46.0,nonessential
982,HNEAP_RS05190,WP_012823904.1,502586140.0,1115219,1116595,1376.0,-,adenylosuccinate lyase,0.5715,18,3.643354207906204e-23,8.773196932638139e-20,1.0,3.476444743905828e-24,8.371278943325235e-21,0.0,essential
983,HNEAP_RS05195,WP_012823905.1,502586141.0,1116634,1117524,890.0,-,recombination-associated protein RdgC,0.5488,12,0.654085189579755,1575.03713650805,37.0,0.5273015931949451,1269.7422364134277,34.0,nonessential
984,HNEAP_RS05200,WP_012823906.1,502586142.0,1117903,1120533,2630.0,+,aminopeptidase N,0.5363,60,0.9999996493535847,2407.999155643432,157.0,0.9999949049650407,2407.987731155818,147.0,nonessential
985,HNEAP_RS05205,WP_012823907.1,502586143.0,1120598,1121449,851.0,+,flagellar motor stator protein MotA,0.5223,31,0.6911694780514168,1664.3361031478116,36.0,0.6311072004121505,1519.7061385924585,34.0,nonessential
986,HNEAP_RS05210,WP_012823908.1,502586144.0,1121489,1122565,1076.0,+,motility protein MotB,0.533,18,0.6757239544367852,1627.143282283779,45.0,0.6937104188584774,1670.4546886112137,44.0,nonessential
987,HNEAP_RS05215,WP_012823909.1,502586145.0,1122575,1123336,761.0,+,class I SAM-dependent methyltransferase,0.5105,14,0.1929576671496746,464.64206249641643,25.0,0.24168751570676703,581.983537821895,25.0,nonessential
988,HNEAP_RS05220,WP_012823910.1,502586146.0,1123487,1123783,296.0,-,RNA-binding protein,0.5118,6,0.16688083639083398,401.84905402912824,8.0,0.11472553972099811,276.25909964816344,7.0,nonessential
989,HNEAP_RS05225,WP_012823911.1,502586147.0,1124037,1124927,890.0,-,DUF815 domain-containing protein,0.5253,10,0.9933929302196689,2392.0901759689627,50.0,0.9941284348541268,2393.8612711287374,49.0,nonessential
990,HNEAP_RS12220,WP_012823912.1,502586148.0,1125087,1125590,503.0,+,thiol reductase thioredoxin,0.5238,12,0.2952232273770003,710.8975315238167,17.0,0.25999010831619707,626.0561808254025,16.0,nonessential
991,HNEAP_RS05235,WP_012823913.1,502586149.0,1125873,1126979,1106.0,+,glycosyltransferase,0.5294,24,6.985242141334426e-15,1.68204630763333e-11,4.0,2.154536213623158e-15,5.188123202404565e-12,3.0,essential
992,HNEAP_RS12225,WP_012823914.1,502586150.0,1126976,1127824,848.0,+,phosphatase PAP2 family protein,0.5713,17,0.0009982409108107084,2.4037641132321856,17.0,0.0003781699841708544,0.9106333218834174,15.0,nonessential
993,HNEAP_RS05245,WP_012823915.1,502586151.0,1127935,1129200,1265.0,+,glutamyl-tRNA reductase,0.5561,25,3.005298593479838e-21,7.23675901309945e-18,1.0,1.401417925132898e-20,3.374614363720018e-17,1.0,essential
994,HNEAP_RS05250,WP_012823916.1,502586152.0,1129276,1130370,1094.0,+,peptide chain release factor 1,0.5763,17,1.0881684949478285e-14,2.620309735834371e-11,4.0,3.342268231919328e-15,8.048181902461741e-12,3.0,essential
995,HNEAP_RS05255,WP_012823917.1,502586153.0,1130388,1131248,860.0,+,protein-(glutamine-N5) methyltransferase  release factor-specific,0.5645,17,0.466624952651702,1123.6328859852983,33.0,0.5386424264499591,1297.0509628915015,33.0,nonessential
996,HNEAP_RS05260,WP_012823918.1,502586154.0,1131420,1131842,422.0,+,hypothetical protein,0.5343,4,0.0895486463532752,215.63314041868668,11.0,0.11061707866825661,266.3659254331619,11.0,nonessential
997,HNEAP_RS05265,WP_012823919.1,502586155.0,1131879,1132640,761.0,+,molybdopterin-synthase adenylyltransferase MoeB,0.5381,17,4.1268008325467175e-14,9.937336404772495e-11,0.0,1.0617452806283746e-13,2.556682635753126e-10,0.0,essential
998,HNEAP_RS05270,WP_012823920.1,502586156.0,1132920,1134053,1133.0,-,quinone-dependent dihydroorotate dehydrogenase,0.5591,17,2.4566707801881496e-14,5.915663238693064e-11,5.0,8.589936438318135e-14,2.068456694347007e-10,5.0,essential
999,HNEAP_RS05275,WP_012823921.1,502586157.0,1134159,1134992,833.0,+,GNAT family N-acetyltransferase,0.4868,22,0.00029499757126196495,0.7103541515988115,15.0,9.32984577869904e-05,0.2246626863510729,13.0,nonessential
1000,HNEAP_RS05280,WP_012823922.1,502586158.0,1135079,1135489,410.0,+,hypothetical protein,0.5134,6,0.635142436575338,1529.4229872734138,17.0,0.6816827945044607,1641.4921691667414,17.0,nonessential
1001,HNEAP_RS05285,WP_012823923.1,502586159.0,1135660,1136589,929.0,+,protease HtpX,0.5333,20,1.3147895600641072e-06,0.00316601326063437,12.0,9.074522672843995e-07,0.002185145059620834,11.0,essential
1002,HNEAP_RS05290,WP_012823924.1,502586160.0,1136781,1136996,215.0,+,cbb3-type cytochrome oxidase assembly protein CcoS,0.4537,5,0.0081356205944148,19.590574391350838,2.0,0.010042633394752764,24.182661214564657,2.0,nonessential
1003,HNEAP_RS05295,WP_012823925.1,502586161.0,1137060,1139117,2057.0,-,methionine--tRNA ligase,0.5462,40,1.5096557927804854e-30,3.6352511490154086e-27,4.0,1.712797798441671e-29,4.124417098647544e-26,4.0,essential
1004,HNEAP_RS05300,WP_041600375.1,753844758.0,1139310,1140233,923.0,+,hypothetical protein,0.5195,24,0.9999681975599989,2407.9234197244773,62.0,0.9997526434275545,2407.404365373551,57.0,nonessential
1005,HNEAP_RS05305,WP_012823927.1,502586163.0,1140251,1141309,1058.0,+,UDP-N-acetylmuramate dehydrogenase,0.5335,27,1.102982046862645e-17,2.6559807688452492e-14,1.0,9.174619609513388e-19,2.209248401970824e-15,0.0,essential
1006,HNEAP_RS05310,WP_012823928.1,502586164.0,1141505,1142149,644.0,+,peroxiredoxin,0.5101,13,0.20909030847875823,503.4894628168498,21.0,0.13754105581286963,331.1988623973901,19.0,nonessential
1007,HNEAP_RS05315,WP_012823929.1,502586165.0,1142252,1142920,668.0,-,hypothetical protein,0.4798,19,0.050113307139512314,120.67284359194565,18.0,0.042975725069639106,103.48554596769097,17.0,nonessential
1008,HNEAP_RS05320,WP_012823930.1,502586166.0,1143157,1144404,1247.0,-,hypothetical protein,0.5128,18,0.966871542732913,2328.2266749008545,62.0,0.9804679902124617,2360.966920431608,62.0,nonessential
1009,HNEAP_RS12230,WP_081441180.1,1174219999.0,1144401,1146410,2009.0,-,hypothetical protein,0.5224,45,0.9613055097544844,2314.8236674887985,95.0,0.9468423348791908,2279.9963423890913,91.0,nonessential
1010,HNEAP_RS05330,WP_012823932.1,502586168.0,1146337,1148001,1664.0,+,energy-dependent translational throttle protein EttA,0.5441,24,0.6278057310800316,1511.756200440716,68.0,0.675292287506446,1626.103828315522,67.0,nonessential
1011,HNEAP_RS05335,WP_041600376.1,753844759.0,1148039,1148905,866.0,+,HDOD domain-containing protein,0.5202,22,0.00884304849901226,21.29406078562152,21.0,0.004477983213779007,10.782983578779849,19.0,nonessential
1012,HNEAP_RS05340,WP_012823934.1,502586170.0,1148902,1149201,299.0,-,hypothetical protein,0.5067,4,0.9457243734974101,2277.3042913817635,17.0,0.9572151290281004,2304.9740306996655,17.0,nonessential
1013,HNEAP_RS05345,WP_012823935.1,502586171.0,1149297,1149881,584.0,+,ADP-ribose pyrophosphatase,0.5145,11,0.9998971623674017,2407.7523669807033,42.0,0.9999473842439057,2407.8733012593248,42.0,nonessential
1014,HNEAP_RS05350,WP_012823936.1,502586172.0,1150262,1152844,2582.0,+,aconitate hydratase B,0.5629,50,8.05949202267344e-41,1.9407256790597644e-37,3.0,1.810450386097419e-39,4.359564529722585e-36,3.0,essential
1015,HNEAP_RS05355,WP_012823937.1,502586173.0,1152952,1154061,1109.0,+,hypothetical protein,0.3468,66,3.165090933181158e-05,0.07621538967100229,20.0,6.800101054005695e-05,0.16374643338045713,20.0,nonessential
1016,HNEAP_RS05360,WP_012823938.1,502586174.0,1154084,1154797,713.0,-,YebC/PmpR family DNA-binding regulatory protein,0.535,10,0.8809946300865342,2121.4350692483745,34.0,0.8788124162082444,2116.1802982294525,33.0,nonessential
1017,HNEAP_RS05365,WP_041600378.1,753844761.0,1155071,1155289,218.0,+,hypothetical protein,0.5708,2,0.946066420906809,2278.127941543596,13.0,0.9195465556951248,2214.2681061138605,12.0,nonessential
1018,HNEAP_RS05370,WP_012823940.1,502586176.0,1155299,1155766,467.0,+,YcgN family cysteine cluster protein,0.5192,7,0.9996933822845415,2407.261664541176,34.0,0.9996369583128262,2407.1257956172853,33.0,nonessential
1019,HNEAP_RS05375,WP_012823941.1,502586178.0,1155793,1156740,947.0,-,tRNA glutamyl-Q(34) synthetase GluQRS,0.5601,21,0.9274750037554428,2233.359809043106,46.0,0.8463726248658217,2038.0652806768985,42.0,nonessential
1020,HNEAP_RS05380,WP_012823942.1,502586179.0,1156817,1158967,2150.0,+,lytic transglycosylase,0.5407,53,5.447793762686057e-06,0.013118287380548025,48.0,2.860173286679765e-06,0.006887297274324874,45.0,essential
1021,HNEAP_RS05385,WP_012823943.1,502586180.0,1158967,1160454,1487.0,+,exodeoxyribonuclease I,0.5531,24,0.9989872823833615,2405.5613759791345,83.0,0.9993581732742142,2406.4544812443078,82.0,nonessential
1022,HNEAP_RS12235,WP_012823944.1,502586181.0,1160509,1161174,665.0,+,CBS domain-containing protein,0.545,15,0.9416919754056757,2267.594276776867,34.0,0.9587116846491758,2308.5777366352154,34.0,nonessential
1023,HNEAP_RS05395,WP_012823945.1,502586182.0,1161187,1161615,428.0,-,DUF1841 domain-containing protein,0.5478,7,0.8667598690856047,2087.157764758136,21.0,0.3203816128885772,771.4789238356939,14.0,nonessential
1024,HNEAP_RS05400,WP_012823946.1,502586183.0,1161602,1162309,707.0,-,endonuclease III,0.5494,19,0.9999999999999988,2407.9999999999973,77.0,0.9999999999999382,2407.9999999998513,72.0,nonessential
1025,HNEAP_RS05405,WP_012823947.1,502586184.0,1162496,1163041,545.0,+,hypothetical protein,0.5403,16,0.9928146588280736,2390.6976984580015,33.0,0.9973950210892987,2401.7272107830313,34.0,nonessential
1026,HNEAP_RS05410,WP_012823948.1,502586185.0,1163053,1163628,575.0,+,ATP:cob(I)alamin adenosyltransferase,0.5799,7,0.08328095101856005,200.5405300526926,16.0,0.2190143200806688,527.3864827542504,18.0,nonessential
1027,HNEAP_RS05415,WP_012823949.1,502586186.0,1163631,1164827,1196.0,-,pyridoxal phosphate-dependent aminotransferase,0.5272,30,0.8155510754141624,1963.846989597303,53.0,0.8678878801476697,2089.8740153955887,53.0,nonessential
1028,HNEAP_RS05420,WP_012823950.1,502586187.0,1164824,1166926,2102.0,-,SAM-dependent methyltransferase,0.5311,42,0.42126234410448926,1014.3997246036101,81.0,0.31291285029743826,753.4941435162314,76.0,nonessential
1029,HNEAP_RS05425,WP_012823951.1,502586188.0,1166997,1167746,749.0,-,DUF481 domain-containing protein,0.5187,22,0.9999999237721419,2407.9998164433177,61.0,0.9999999736893438,2407.9999366439397,61.0,nonessential
1030,HNEAP_RS05430,WP_012823952.1,502586189.0,1167853,1168593,740.0,-,1-acyl-sn-glycerol-3-phosphate acyltransferase,0.556,19,0.8742830311545575,2105.2735390201747,35.0,0.8732253425312139,2102.726624815163,34.0,nonessential
1031,HNEAP_RS05435,WP_012823953.1,502586190.0,1168602,1169171,569.0,-,CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase,0.5474,16,9.828538533219932e-11,2.3667120787993597e-07,0.0,1.992279623293549e-10,4.797409332890866e-07,0.0,essential
1032,HNEAP_RS05440,WP_081441181.1,1174220000.0,1169168,1169932,764.0,-,UDP-2 3-diacylglucosamine diphosphatase,0.5529,16,3.6546839907228185e-14,8.800479049660547e-11,0.0,9.437882338863378e-14,2.2726420671983013e-10,0.0,essential
1033,HNEAP_RS05445,WP_012823955.1,502586192.0,1169985,1170500,515.0,-,cyclophilin,0.5756,11,0.998306177110554,2403.921274482214,34.0,0.9318691165627822,2243.9408326831795,26.0,nonessential
1034,HNEAP_RS05450,WP_012823956.1,502586193.0,1170821,1172185,1364.0,+,cysteine--tRNA ligase,0.5575,32,1.683900986459027e-21,4.054833575393337e-18,2.0,3.096492222148839e-22,7.4563532709344045e-19,1.0,essential
1035,HNEAP_RS05460,WP_012823958.1,502586195.0,1172534,1173697,1163.0,+,phosphoesterase DHHA1,0.5593,22,6.762297935968745e-14,1.6283613429812738e-10,6.0,3.006460259513733e-14,7.239556304909068e-11,5.0,essential
1036,HNEAP_RS05465,WP_012823959.1,502586196.0,1173726,1174253,527.0,+,transcription elongation factor GreB,0.5417,6,0.999999999952791,2407.999999886321,55.0,0.9999999999849053,2407.999999963652,55.0,nonessential
1037,HNEAP_RS05470,WP_012823960.1,502586197.0,1174386,1176647,2261.0,+,lysine decarboxylase,0.5349,38,0.3288425427848988,791.8528430260362,85.0,0.3967362149095232,955.3408055021318,84.0,nonessential
1038,HNEAP_RS05475,WP_012823961.1,502586198.0,1176647,1177618,971.0,+,UDP-glucose 4-epimerase GalE,0.5412,26,0.7951796640403714,1914.7926310092143,43.0,0.7583686875830955,1826.151799700094,41.0,nonessential
1039,HNEAP_RS05480,WP_012823962.1,502586199.0,1177784,1179124,1340.0,+,sensor domain-containing diguanylate cyclase,0.5287,28,0.8130159032362279,1957.7422949928366,59.0,0.7609519798128732,1832.3723673893987,56.0,nonessential
1040,HNEAP_RS05490,WP_012823963.1,502586200.0,1179635,1180537,902.0,+,LysR family transcriptional regulator,0.5227,31,0.07405707460690635,178.32943565343047,27.0,0.05001430155936908,120.43443815496074,25.0,nonessential
1041,HNEAP_RS05495,WP_012823964.1,502586201.0,1180592,1182862,2270.0,-,VWA domain-containing protein,0.5487,51,0.9987835644608726,2405.070823221781,119.0,0.9994051838879934,2406.567682802288,118.0,nonessential
1042,HNEAP_RS12520,WP_012823965.1,502586202.0,1182855,1183082,227.0,-,hypothetical protein,0.5219,5,0.2004168572656926,482.6037922957878,6.0,0.22633338625147975,545.0107940935633,6.0,nonessential
1043,HNEAP_RS05500,WP_012823966.1,502586203.0,1183099,1183902,803.0,-,CbbQ/NirQ/NorQ/GpvN family protein,0.5311,16,0.059937672181572754,144.3299146132272,23.0,0.05600212090510886,134.85310713950213,22.0,nonessential
1044,HNEAP_RS05505,WP_012823967.1,502586204.0,1184110,1185489,1379.0,-,ribulose-bisphosphate carboxylase,0.5478,28,0.2845186245494233,685.1208479150113,50.0,0.3658257569729993,880.9084227909823,50.0,nonessential
1045,HNEAP_RS05510,WP_012823968.1,502586205.0,1185619,1186521,902.0,+,LysR family transcriptional regulator,0.5183,20,0.9999457607712497,2407.8693919371694,60.0,0.9999769074211458,2407.944393070119,60.0,nonessential
1046,HNEAP_RS05515,WP_012823969.1,502586206.0,1186731,1188089,1358.0,-,dicarboxylate/amino acid:cation symporter,0.5136,42,0.8543214334530986,2057.2060117550614,61.0,0.9010933336037513,2169.8327473178333,61.0,nonessential
1047,HNEAP_RS05520,WP_012823971.1,502586208.0,1188327,1189022,695.0,-,urea ABC transporter ATP-binding subunit UrtE,0.5431,19,0.8733139316990985,2102.9399475314294,33.0,0.9049963543956173,2179.2312213846467,33.0,nonessential
1048,HNEAP_RS05525,WP_012823972.1,502586209.0,1189010,1189840,830.0,-,urea ABC transporter ATP-binding protein UrtD,0.5451,11,0.83890127496314,2020.0742701112413,38.0,0.796792576335372,1918.6765238155758,36.0,nonessential
1049,HNEAP_RS05530,WP_012823973.1,502586210.0,1189840,1190991,1151.0,-,urea ABC transporter permease subunit UrtC,0.5564,30,0.2196206813520388,528.8466006957094,40.0,0.18797452068529624,452.64264581019336,38.0,nonessential
1050,HNEAP_RS05535,WP_012823974.1,502586211.0,1190995,1192680,1685.0,-,urea ABC transporter permease subunit UrtB,0.5641,35,0.997602532829704,2402.2268990539274,90.0,0.9985274177305075,2404.454021895062,89.0,nonessential
1051,HNEAP_RS05540,WP_012823975.1,502586212.0,1192748,1194049,1301.0,-,urea ABC transporter substrate-binding protein,0.5422,21,0.9995554518724675,2406.9295281089016,76.0,0.9997046804616649,2407.2888705516893,75.0,nonessential
1052,HNEAP_RS05545,WP_012823976.1,502586214.0,1194089,1194889,800.0,-,GntR family transcriptional regulator,0.5705,13,0.5647167268656811,1359.8378782925602,32.0,0.48959154068306154,1178.9364299648123,30.0,nonessential
1053,HNEAP_RS05550,WP_012823977.1,502586215.0,1194886,1198512,3626.0,-,urea carboxylase,0.579,72,0.9999854985333531,2407.965080468314,195.0,0.9999718192531506,2407.9321407615867,188.0,nonessential
1054,HNEAP_RS05555,WP_012823978.1,502586216.0,1198505,1200355,1850.0,-,allophanate hydrolase,0.5613,42,0.9999823051274948,2407.957390747007,110.0,0.9999872503364433,2407.9692988101556,108.0,nonessential
1055,HNEAP_RS12240,WP_012823979.1,502586217.0,1200559,1201596,1037.0,-,molybdopterin molybdenumtransferase MoeA,0.5934,21,0.9999999973054934,2407.999993511628,82.0,0.9999999967641201,2407.999992208001,80.0,nonessential
1056,HNEAP_RS05565,WP_012823980.1,502586218.0,1201593,1202195,602.0,-,molybdenum cofactor guanylyltransferase,0.6003,8,0.9999997796139962,2407.9994693105027,51.0,0.9999999127445953,2407.9997898889856,51.0,nonessential
1057,HNEAP_RS05570,WP_012823981.1,502586219.0,1202192,1203046,854.0,-,uroporphyrinogen III synthase HEM4,0.5953,23,0.9999276875132727,2407.8258715319607,57.0,0.9996607059027716,2407.1829798138738,53.0,nonessential
1058,HNEAP_RS05575,WP_012823982.1,502586220.0,1203101,1203934,833.0,-,formate transporter,0.5576,17,0.9999999680512571,2407.999923067427,67.0,0.9999999773124514,2407.999945368383,66.0,nonessential
1059,HNEAP_RS05580,WP_012823983.1,502586221.0,1204033,1205481,1448.0,-,uroporphyrinogen-III C-methyltransferase,0.6073,22,0.999999997251375,2407.999993381311,105.0,0.9999999917979857,2407.9999802495495,101.0,nonessential
1060,HNEAP_RS05585,WP_012823984.1,502586222.0,1205486,1208245,2759.0,-,nitrate reductase,0.5909,50,0.9997996219105729,2407.5174895606597,147.0,0.999925132500511,2407.8197190612304,146.0,nonessential
1061,HNEAP_RS05590,WP_012823985.1,502586223.0,1208249,1208611,362.0,-,nitrite reductase (NAD(P)H) small subunit,0.5785,5,0.865738925346647,2084.6993322347257,18.0,0.8905425196702494,2144.4263873659606,18.0,nonessential
1062,HNEAP_RS05595,WP_012823986.1,502586224.0,1208623,1211061,2438.0,-,nitrite reductase large subunit,0.5761,42,0.9994228445111404,2406.610209582826,129.0,0.9998216098951918,2407.570436627622,129.0,nonessential
1063,HNEAP_RS05600,WP_012823987.1,502586225.0,1211661,1213136,1475.0,+,nitrate ABC transporter substrate-binding protein,0.5325,32,0.9946749010873956,2395.177161818449,78.0,0.9974701674255915,2401.908163160824,78.0,nonessential
1064,HNEAP_RS05605,WP_012823988.1,502586226.0,1213133,1214095,962.0,+,ABC transporter permease,0.5493,20,0.9998224786372744,2407.5725285585568,61.0,0.9999214411517682,2407.810830293458,61.0,nonessential
1065,HNEAP_RS05610,WP_012823989.1,502586227.0,1214125,1214922,797.0,+,ABC transporter ATP-binding protein,0.5226,14,0.42920233628401194,1033.5192257719007,30.0,0.6405693804952324,1542.4910682325196,32.0,nonessential
1066,HNEAP_RS05615,WP_012823990.1,502586228.0,1214974,1216257,1283.0,+,ANTAR domain-containing protein with unknown sensor,0.5296,24,0.9999999997010257,2407.99999928007,99.0,0.999999999872955,2407.9999996940755,98.0,nonessential
1067,HNEAP_RS05620,WP_041600768.1,753845151.0,1216991,1218451,1460.0,+,cytochrome-c oxidase  cbb3-type subunit I,0.5099,49,0.9999999712437072,2407.999930754847,102.0,0.999999998291653,2407.9999958863004,104.0,nonessential
1068,HNEAP_RS05625,WP_012823992.1,502586230.0,1218603,1220789,2186.0,+,DNA helicase II,0.5524,39,0.24925966494113652,600.2172731782567,80.0,0.34772650274241007,837.3254186037235,80.0,nonessential
1069,HNEAP_RS05630,WP_012823993.1,502586231.0,1220822,1221505,683.0,-,metal-dependent transcriptional regulator,0.5512,9,0.039692948039505814,95.58061887913,18.0,0.03396121666784667,81.77860973617479,17.0,nonessential
1070,HNEAP_RS05635,WP_012823994.1,502586232.0,1221520,1222059,539.0,-,gamma carbonic anhydrase family protein,0.5389,9,0.9938798460905487,2393.262669386041,33.0,0.9960960845979027,2398.5993717117494,33.0,nonessential
1071,HNEAP_RS05640,WP_012823995.1,502586233.0,1222290,1222757,467.0,+,cytochrome C prime,0.5043,7,0.11249407171855688,270.88572469828495,13.0,0.08820938410489627,212.40819692459021,12.0,nonessential
1072,HNEAP_RS05645,WP_012823996.1,502586234.0,1223002,1224645,1643.0,+,methyl-accepting chemotaxis protein,0.5043,30,0.027897346363589752,67.17681004352413,50.0,0.025648750048545946,61.76219011689864,48.0,nonessential
1073,HNEAP_RS05650,WP_012823997.1,502586235.0,1224683,1224997,314.0,-,Na+/H+ antiporter subunit G,0.4952,3,4.195883868371321e-05,0.10103688355038141,1.0,6.016841064383363e-05,0.14488553283035138,1.0,nonessential
1074,HNEAP_RS05655,WP_012823998.1,502586236.0,1225000,1225308,308.0,-,K+/H+ antiporter subunit F,0.5049,11,0.00036164716426455697,0.8708463715490532,2.0,0.0005000120767876762,1.2040290809047245,2.0,nonessential
1075,HNEAP_RS05660,WP_012823999.1,502586237.0,1225305,1225823,518.0,-,Na+/H+ antiporter subunit E,0.5511,12,7.753030315808853e-10,1.866929700046772e-06,0.0,1.4751241124760017e-09,3.5520988628422122e-06,0.0,essential
1076,HNEAP_RS05665,WP_012824000.1,502586238.0,1225820,1227442,1622.0,-,monovalent cation/H+ antiporter subunit D,0.5514,39,2.520962287430043e-18,6.070477188131544e-15,9.0,1.426418608025032e-17,3.434816008124277e-14,9.0,essential
1077,HNEAP_RS05670,WP_012824001.1,502586239.0,1227439,1227795,356.0,-,Na+/H+ antiporter subunit C,0.5406,9,0.00035615016664772585,0.8576096012877238,3.0,0.0005072971073254053,1.2215714344395758,3.0,nonessential
1078,HNEAP_RS05675,WP_012824002.1,502586240.0,1227795,1230626,2831.0,-,monovalent cation/H+ antiporter subunit A,0.5526,60,2.186681477048485e-33,5.265528996732752e-30,13.0,5.5719946852662066e-33,1.3417363202121026e-29,12.0,essential
1079,HNEAP_RS05680,WP_081441111.1,1174219930.0,1230935,1232305,1370.0,+,polynucleotide adenylyltransferase PcnB,0.5492,25,5.8435708221672374e-09,1.4071318539778708e-05,18.0,1.834030030463722e-08,4.4163443133566426e-05,18.0,essential
1080,HNEAP_RS05685,WP_012824004.1,502586242.0,1232325,1232879,554.0,+,2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase,0.5586,8,4.3115724051892326e-09,1.0382266351695672e-05,1.0,9.646626433164792e-08,0.00023229076451060818,2.0,essential
1081,HNEAP_RS05690,WP_012824005.1,502586243.0,1232884,1233726,842.0,+,3-methyl-2-oxobutanoate hydroxymethyltransferase,0.567,20,1.5523662253064077e-15,3.7380978705378295e-12,0.0,4.416561323947195e-15,1.0635079668064846e-11,0.0,essential
1082,HNEAP_RS05695,WP_012824006.1,502586244.0,1233727,1234578,851.0,+,pantoate--beta-alanine ligase,0.5481,18,3.8999737983383403e-14,9.391136906398724e-11,1.0,1.0879179629167347e-13,2.6197064547034974e-10,1.0,essential
1083,HNEAP_RS05700,WP_012824007.1,502586245.0,1234631,1235590,959.0,+,acetyl-CoA carboxylase carboxyltransferase subunit alpha,0.5542,12,5.522096933571405e-16,1.3297209416039943e-12,1.0,1.76132817381446e-15,4.24127824254522e-12,1.0,essential
1084,HNEAP_RS05705,WP_012824008.1,502586246.0,1235628,1236962,1334.0,+,tRNA(Ile)-lysidine synthetase,0.5543,21,1.5956522605879822e-17,3.842330643495861e-14,5.0,6.478407606140978e-16,1.5600005515587475e-12,6.0,essential
1085,HNEAP_RS05710,WP_012824009.1,502586247.0,1237117,1237866,749.0,+,Nif3-like dinuclear metal center hexameric protein,0.5347,15,0.9825822956317127,2366.058167881164,41.0,0.9889687007270715,2381.4366313507885,41.0,nonessential
1086,HNEAP_RS05715,WP_012824010.1,502586248.0,1238164,1238760,596.0,+,ubiquinol-cytochrome c reductase iron-sulfur subunit,0.536,16,3.293182785868707e-11,7.929984148371847e-08,0.0,6.903006277537521e-11,1.662243911631035e-07,0.0,essential
1087,HNEAP_RS05720,WP_012824011.1,502586250.0,1238757,1239968,1211.0,+,cytochrome b,0.5041,27,2.5647838727975154e-20,6.175999565696417e-17,1.0,1.1184591906895247e-19,2.6932497311803756e-16,1.0,essential
1088,HNEAP_RS05725,WP_012824012.1,502586251.0,1239965,1240723,758.0,+,cytochrome c1,0.498,31,4.6599063434045397e-14,1.1221054474918132e-10,0.0,1.1944448981892997e-13,2.876223314839834e-10,0.0,essential
1089,HNEAP_RS05730,WP_012824013.1,502586252.0,1240805,1242103,1298.0,+,PAS/PAC sensor-containing diguanylate cyclase,0.4988,37,0.09715124962644608,233.94020910048218,42.0,0.17601957274455018,423.8551311688768,43.0,nonessential
1090,HNEAP_RS05755,WP_012824014.1,502586253.0,1242912,1243421,509.0,-,heme-binding protein,0.5647,8,0.9998107013184401,2407.544168774804,37.0,0.9995720991767731,2406.96961481767,35.0,nonessential
1091,HNEAP_RS05760,WP_012824016.1,502586255.0,1243900,1244241,341.0,+,type IV pilus assembly PilZ,0.5292,15,0.9997224631880836,2407.331691356905,27.0,0.9996104761930739,2407.062026672922,26.0,nonessential
1092,HNEAP_RS05765,WP_012824017.1,502586256.0,1244353,1245912,1559.0,+,glycosyl transferase family 39,0.4949,55,2.49036406524059e-26,5.996796669099341e-23,1.0,1.6728155952280566e-25,4.0281399533091605e-22,1.0,essential
1093,HNEAP_RS05770,WP_012824018.1,502586257.0,1245955,1246437,482.0,+,hypothetical protein,0.528,11,0.3635388508652665,875.4015528835617,17.0,0.24014499817768709,578.2691556118705,15.0,nonessential
1094,HNEAP_RS05775,WP_012824019.1,502586258.0,1246475,1247518,1043.0,+,dihydroorotase,0.5421,29,4.401675136414237e-16,1.0599233728485484e-12,2.0,1.510651050469499e-15,3.6376477295305537e-12,2.0,essential
1095,HNEAP_RS05780,WP_012824020.1,502586259.0,1247515,1248606,1091.0,+,tRNA pseudouridine(13) synthase TruD,0.5192,28,0.11072772177750878,266.6323540402411,35.0,0.08698914008714118,209.46984932983594,33.0,nonessential
1096,HNEAP_RS05785,WP_012824021.1,502586260.0,1248650,1248988,338.0,-,monothiol glutaredoxin  Grx4 family,0.4572,12,0.007296255152025003,17.569382406076205,5.0,0.009606189547938461,23.131704431435814,5.0,nonessential
1097,HNEAP_RS05790,WP_012824022.1,502586261.0,1249049,1250692,1643.0,-,diguanylate cyclase response regulator,0.4866,33,2.4542233907774532e-09,5.909769924992107e-06,24.0,2.378946029684535e-08,5.72850203948036e-05,25.0,essential
1098,HNEAP_RS05795,WP_012824023.1,502586262.0,1251163,1253034,1871.0,-,dihydroxy-acid dehydratase,0.5337,46,1.2389460625415645e-33,2.9833821186000873e-30,0.0,1.2649738383397035e-32,3.046057002722006e-29,0.0,essential
1099,HNEAP_RS05800,WP_081441182.1,1174220001.0,1253142,1253711,569.0,-,L D-transpeptidase,0.4982,14,0.1921933162085197,462.80150543011547,18.0,0.23370288340993098,562.7565432511138,18.0,nonessential
1100,HNEAP_RS05805,WP_012824025.1,502586264.0,1253794,1255314,1520.0,-,amidophosphoribosyltransferase,0.5161,33,1.8467274504505625e-27,4.4469197006849544e-24,0.0,1.2193766251259225e-26,2.9362589133032213e-23,0.0,essential
1101,HNEAP_RS05810,WP_012824026.1,502586265.0,1255373,1255861,488.0,-,colicin V production protein CvpA,0.501,12,0.01367721042275976,32.9347226980055,10.0,0.018708709722519527,45.05057301182702,10.0,nonessential
1102,HNEAP_RS05815,WP_012824027.1,502586266.0,1255905,1256669,764.0,-,sporulation domain-containing protein,0.5542,15,0.028743632931874534,69.21466809995388,20.0,0.04107069008462238,98.89822172377069,20.0,nonessential
1103,HNEAP_RS05820,WP_041600382.1,753844765.0,1256653,1257957,1304.0,-,bifunctional folylpolyglutamate synthase/dihydrofolate synthase,0.5433,27,1.1624858341054537e-23,2.7992658885259327e-20,0.0,5.869945426698781e-23,1.4134828587490664e-19,0.0,essential
1104,HNEAP_RS05825,WP_012824029.1,502586268.0,1257954,1258826,872.0,-,acetyl-CoA carboxylase carboxyltransferase subunit beta,0.5475,10,4.606354932468658e-16,1.1092102677384529e-12,0.0,1.3602741960275216e-15,3.275540264034272e-12,0.0,essential
1105,HNEAP_RS05830,WP_012824030.1,502586269.0,1258866,1259696,830.0,-,tryptophan synthase subunit alpha,0.5439,14,2.5237649231451495e-15,6.07722593493352e-12,0.0,7.074037978800459e-15,1.7034283452951507e-11,0.0,essential
1106,HNEAP_RS05835,WP_012824031.1,502586270.0,1259693,1260949,1256.0,-,tryptophan synthase subunit beta,0.537,26,4.296711370186756e-21,1.0346480979409707e-17,1.0,1.98136448954979e-20,4.771125690835895e-17,1.0,essential
1107,HNEAP_RS05840,WP_041600780.1,753845163.0,1260942,1261583,641.0,-,phosphoribosylanthranilate isomerase,0.5265,10,5.323051359396722e-12,1.2817907673427307e-08,0.0,1.179917277132968e-11,2.841240803336187e-08,0.0,essential
1108,HNEAP_RS05845,WP_012824033.1,502586272.0,1261738,1262553,815.0,-,tRNA pseudouridine(38-40) synthase,0.5564,25,0.9732336949445859,2343.5467374265627,43.0,0.9886726931850306,2380.7238451895537,44.0,nonessential
1109,HNEAP_RS05850,WP_049772477.1,908628444.0,1262768,1264432,1664.0,+,TolC family protein,0.5165,32,0.9975811978863716,2402.1755245103827,89.0,0.996908661227446,2400.55605623569,86.0,nonessential
1110,HNEAP_RS05855,WP_012824035.1,502586274.0,1264434,1265567,1133.0,+,efflux RND transporter periplasmic adaptor subunit,0.5353,22,0.7102684103486617,1710.3263321195775,48.0,0.7307550148102304,1759.6580756630349,47.0,nonessential
1111,HNEAP_RS05860,WP_012824036.1,502586275.0,1265564,1268896,3332.0,+,AcrB/AcrD/AcrF family protein,0.5344,69,0.9997776853273415,2407.464666268238,173.0,0.9999286138734762,2407.8281022073306,172.0,nonessential
1112,HNEAP_RS05865,WP_081441112.1,1174219931.0,1269101,1270981,1880.0,+,hypothetical protein,0.5141,45,0.6819895957538602,1642.2309465752953,78.0,0.6520492345140083,1570.1345567097321,75.0,nonessential
1113,HNEAP_RS05870,WP_012824038.1,502586277.0,1270978,1271643,665.0,+,outer membrane lipoprotein LolB,0.5255,18,5.736502878267411e-11,1.3813498930867927e-07,1.0,1.2705052863272414e-10,3.059376729475997e-07,1.0,essential
1114,HNEAP_RS05875,WP_012824039.1,502586278.0,1271640,1272539,899.0,+,4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase,0.5333,22,5.888862523334124e-15,1.4180380956188571e-11,1.0,1.74354078810402e-14,4.1984462177544803e-11,1.0,essential
1115,HNEAP_RS05885,WP_012824040.1,502586279.0,1272716,1273672,956.0,+,ribose-phosphate pyrophosphokinase,0.5392,18,1.5345265101859465e-17,3.695139836527759e-14,0.0,5.0297292183556126e-17,1.2111587957800314e-13,0.0,essential
1116,HNEAP_RS05890,WP_012824041.1,502586280.0,1273919,1274533,614.0,+,50S ribosomal protein L25,0.5203,9,2.8076840233161033e-05,0.06760903128145176,7.0,1.3298806873578342e-05,0.03202352695157665,6.0,ambiguous
1117,HNEAP_RS05895,WP_012824042.1,502586281.0,1274658,1275242,584.0,+,aminoacyl-tRNA hydrolase,0.506,11,1.41733272822786e-07,0.00034129372095726866,3.0,3.2866463535112055e-08,7.914244419254983e-05,2.0,essential
1118,HNEAP_RS05900,WP_012824043.1,502586282.0,1275315,1276409,1094.0,+,redox-regulated ATPase YchF,0.5397,15,0.9983481751452304,2404.022405749715,63.0,0.9987282877800743,2404.937716974419,62.0,nonessential
1119,HNEAP_RS05905,WP_041600785.1,753845168.0,1276522,1277529,1007.0,+,porphobilinogen synthase,0.5665,20,2.6679228298972943e-13,6.424358174392684e-10,4.0,8.231449842897102e-13,1.9821331221696223e-09,4.0,essential
1120,HNEAP_RS05910,WP_012824046.1,502586285.0,1278257,1279225,968.0,-,DUF697 domain-containing protein,0.5459,19,0.16503622229080334,397.40722327625446,32.0,0.16807097578158597,404.71490968205904,31.0,nonessential
1121,HNEAP_RS05915,WP_012824047.1,502586286.0,1279241,1280572,1331.0,-,hypothetical protein,0.542,37,0.005255690046802105,12.655701632699468,35.0,0.003805579607529612,9.163835694931306,33.0,nonessential
1122,HNEAP_RS05920,WP_049772478.1,908628445.0,1280737,1282026,1289.0,-,EAL domain-containing protein,0.5101,27,0.7366005717317983,1773.7341767301702,55.0,0.7179875980695208,1728.9141361514062,53.0,nonessential
1123,HNEAP_RS05925,WP_012824049.1,502586289.0,1282299,1283225,926.0,+,cation diffusion facilitator transporter,0.521,21,0.05475467202355834,131.84925023272848,27.0,0.023498156059354677,56.58355979092606,24.0,nonessential
1124,HNEAP_RS05930,WP_012824050.1,502586290.0,1283222,1283443,221.0,+,hypothetical protein,0.5,8,0.9985572964933362,2404.5259699559538,18.0,0.9996011944189881,2407.039676160923,19.0,nonessential
1125,HNEAP_RS05935,WP_012824051.1,502586291.0,1283509,1285296,1787.0,-,ABC transporter ATP-binding protein,0.5235,40,0.6288926303926667,1514.3734539855416,73.0,0.6367667352799067,1533.3342985540153,71.0,nonessential
1126,HNEAP_RS05940,WP_012824052.1,502586292.0,1285373,1286902,1529.0,-,apolipoprotein N-acyltransferase,0.5464,32,2.6416225163336185e-24,6.361027019331353e-21,2.0,1.6569516926091032e-23,3.9899396758027205e-20,2.0,essential
1127,HNEAP_RS05945,WP_012824053.1,502586293.0,1286899,1287798,899.0,-,ion transporter,0.5222,19,6.139778732031754e-05,0.14784587186732462,15.0,4.8105169624188306e-05,0.11583724845504544,14.0,nonessential
1128,HNEAP_RS05950,WP_012824054.1,502586294.0,1287874,1288359,485.0,-,rRNA maturation RNase YbeY,0.5165,10,6.535618770776024e-07,0.0015737770000028666,2.0,1.123694680590866e-06,0.0027058567908628053,2.0,essential
1129,HNEAP_RS05955,WP_041600383.1,753844766.0,1288356,1289342,986.0,-,PhoH family protein,0.5491,18,4.4326799233659034e-05,0.10673893255465096,17.0,0.0004307761428345603,1.0373089519456213,19.0,nonessential
1130,HNEAP_RS05960,WP_049772479.1,908628446.0,1289369,1290748,1379.0,-,tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB,0.5493,33,0.440758060348074,1061.3454093181622,53.0,0.420259123163329,1011.9839685772962,51.0,nonessential
1131,HNEAP_RS05965,WP_012824057.1,502586297.0,1290904,1291977,1073.0,-,tRNA dihydrouridine(20/20a) synthase DusA,0.554,24,0.8595485495259505,2069.792907258489,49.0,0.9243465062105537,2225.8263869550133,50.0,nonessential
1132,HNEAP_RS05970,WP_012824058.1,502586298.0,1291982,1293652,1670.0,-,ubiquinone biosynthesis regulatory protein kinase UbiB,0.5206,28,2.427886328159137e-25,5.846350278207202e-22,3.0,7.778596477085985e-26,1.8730860316823054e-22,2.0,essential
1133,HNEAP_RS05975,WP_081441113.1,1174219932.0,1293649,1294398,749.0,-,hypothetical protein,0.5267,15,1.8591120774156922e-08,4.4767418824169865e-05,5.0,6.526964967926188e-09,1.5716931642766263e-05,4.0,essential
1134,HNEAP_RS05980,WP_012824060.1,502586300.0,1294461,1295402,941.0,+,CHAD domain-containing protein,0.482,26,0.910295528896668,2191.9916335831763,45.0,0.9162954940055386,2206.439549565337,44.0,nonessential
1135,HNEAP_RS12245,WP_012824062.1,502586302.0,1297751,1298452,701.0,+,hypothetical protein,0.5328,11,0.9999998023951929,2407.9995241676247,57.0,0.9999999270282413,2407.9998242840047,57.0,nonessential
1136,HNEAP_RS05995,WP_081441183.1,1174220002.0,1298813,1299316,503.0,+,SUF system Fe-S cluster assembly regulator,0.5615,6,0.9274845418617528,2233.3827768031006,26.0,0.616595819293785,1484.7627328594344,20.0,nonessential
1137,HNEAP_RS06000,WP_041600794.1,753845177.0,1299390,1300874,1484.0,+,Fe-S cluster assembly protein SufB,0.5407,39,3.1991718980270046e-22,7.703605930449027e-19,3.0,1.839353330554389e-21,4.429162819974969e-18,3.0,essential
1138,HNEAP_RS06005,WP_012824065.1,502586305.0,1300915,1301673,758.0,+,Fe-S cluster assembly ATPase SufC,0.5217,13,4.6599063434045397e-14,1.1221054474918132e-10,0.0,1.1944448981892997e-13,2.876223314839834e-10,0.0,essential
1139,HNEAP_RS06010,WP_012824066.1,502586306.0,1301670,1302950,1280.0,+,Fe-S cluster assembly protein SufD,0.5597,23,4.461509578950937e-20,1.0743315066113856e-16,2.0,2.054573319351791e-19,4.947412552999113e-16,2.0,essential
1140,HNEAP_RS06015,WP_012824067.1,502586307.0,1302962,1304191,1229.0,+,cysteine desulfurase,0.565,27,0.032066414156175185,77.21592528806984,36.0,0.016457429064624357,39.629489187615455,33.0,nonessential
1141,HNEAP_RS06020,WP_012824068.1,502586308.0,1304200,1304745,545.0,+,putative Fe-S cluster assembly protein SufT,0.5568,14,2.5977561046378015e-10,6.255396699967826e-07,0.0,1.1663541523404259e-08,2.8085807988357454e-05,1.0,essential
1142,HNEAP_RS06025,WP_012824069.1,502586309.0,1304774,1305112,338.0,+,(2Fe-2S)-binding protein,0.5457,13,0.13499185680857448,325.0603911950473,9.0,0.15990029250736557,385.0399043577363,9.0,nonessential
1143,HNEAP_RS06030,WP_012824070.1,502586310.0,1305146,1305574,428.0,+,iron-sulfur cluster assembly accessory protein,0.5058,12,0.0017888736642772257,4.307607783579559,6.0,0.015402752425650684,37.08982784096685,8.0,nonessential
1144,HNEAP_RS06035,WP_012824071.1,502586311.0,1305567,1306004,437.0,+,Fe-S metabolism associated SufE,0.5,11,3.9285260395917084e-07,0.0009459890703336834,1.0,3.546211520420497e-08,8.539277341172557e-05,0.0,essential
1145,HNEAP_RS06040,WP_041600798.1,753845181.0,1306051,1306272,221.0,-,hypothetical protein,0.4685,4,0.8288125969069827,1995.7807333520143,11.0,0.8522358399639341,2052.1839026331536,11.0,nonessential
1146,HNEAP_RS06045,WP_012824073.1,502586313.0,1306348,1307127,779.0,-,oxidoreductase molybdopterin-binding protein,0.4962,23,0.02261648008459247,54.46048404369867,20.0,0.02010558167793307,48.41424068046284,19.0,nonessential
1147,HNEAP_RS06050,WP_012824074.1,502586314.0,1307181,1307825,644.0,-,cytochrome b561,0.5209,15,0.1528785602605395,368.1315731073791,20.0,0.0382928474869521,92.20917674858066,16.0,nonessential
1148,HNEAP_RS06055,WP_012824076.1,502586316.0,1308088,1308492,404.0,+,ECF subfamily RNA polymerase sigma-24 subunit,0.5235,10,0.01972610970340477,47.50047216579869,8.0,0.011807928466618928,28.43349174761838,7.0,nonessential
1149,HNEAP_RS06060,WP_012824077.1,502586317.0,1308489,1311455,2966.0,-,Tn3 family transposase,0.6471,27,0.9999999999999999,2407.9999999999995,218.0,0.9999999999999999,2407.9999999999995,213.0,nonessential
1150,HNEAP_RS06065,WP_012824078.1,502586318.0,1311463,1312023,560.0,-,transposase,0.6132,4,0.9937040700929954,2392.839400783933,34.0,0.9812064583245158,2362.745151645434,31.0,nonessential
1151,HNEAP_RS06070,WP_004636771.1,490774562.0,1312142,1313143,1001.0,-,DUF3330 domain-containing protein,0.6347,8,0.9677720616157899,2330.395124370822,51.0,0.9452334891656211,2276.122241910816,48.0,nonessential
1152,HNEAP_RS06075,WP_004099015.1,490200521.0,1313140,1313376,236.0,-,hypothetical protein,0.6624,3,0.7695693457258974,1853.122984507961,11.0,0.7984493468078228,1922.6660271132373,11.0,nonessential
1153,HNEAP_RS06085,WP_012824079.1,502586319.0,1313628,1315325,1697.0,-,mercury(II) reductase,0.6643,17,0.931701344479159,2243.5368375058147,79.0,0.9347718509922862,2250.930617189425,77.0,nonessential
1154,HNEAP_RS06090,WP_012824080.1,502586321.0,1315366,1315788,422.0,-,mercury transporter MerC,0.6619,2,0.9999566905193982,2407.8957107707106,34.0,0.9999764879959073,2407.943383094145,34.0,nonessential
1155,HNEAP_RS06095,WP_012824081.1,502586322.0,1315824,1316099,275.0,-,mercuric transport protein periplasmic component,0.6232,3,0.9964540701967621,2399.461401033803,20.0,0.9975025095991159,2401.9860431146712,20.0,nonessential
1156,HNEAP_RS06100,WP_012824082.1,502586323.0,1316113,1316463,350.0,-,mercuric ion transporter MerT,0.6268,7,0.9584620469108401,2307.976608961303,20.0,0.9138111551569751,2200.457261617996,18.0,nonessential
1157,HNEAP_RS06105,WP_012824083.1,502586324.0,1316534,1316968,434.0,+,Hg(II)-responsive transcriptional regulator,0.6161,4,0.9332383716172764,2247.2379988544017,23.0,0.9491058180041825,2285.446809754071,23.0,nonessential
1158,HNEAP_RS12525,WP_012824084.1,502586325.0,1317014,1317184,170.0,+,ECF subfamily RNA polymerase sigma-24 subunit,0.5146,9,0.9813412139458381,2363.069643181578,12.0,0.9850936129843928,2372.105420066418,12.0,nonessential
1159,HNEAP_RS06110,WP_012824085.1,502586326.0,1317181,1317822,641.0,+,DUF1109 domain-containing protein,0.5405,17,0.9999999994258746,2407.999998617506,60.0,0.9999999995234057,2407.999998852361,59.0,nonessential
1160,HNEAP_RS06115,WP_012824086.1,502586327.0,1317871,1318197,326.0,-,DUF4282 domain-containing protein,0.5107,9,0.46778115990429225,1126.4170330495358,12.0,0.6234331863690734,1501.2271127767287,13.0,nonessential
1161,HNEAP_RS06120,WP_012824087.1,502586328.0,1318259,1319029,770.0,-,inositol-phosphate phosphatase,0.559,21,2.8663054764931637e-14,6.902063587395538e-11,0.0,7.457323747395886e-14,1.7957235583729295e-10,0.0,essential
1162,HNEAP_RS06130,WP_012824089.1,502586330.0,1319591,1320097,506.0,-,DNA starvation/stationary phase protection protein,0.5286,8,0.9234410732632894,2223.646104418001,26.0,0.9423053947172058,2269.0713904790314,26.0,nonessential
1163,HNEAP_RS06135,WP_012824090.1,502586331.0,1320349,1322070,1721.0,+,glutamine--tRNA ligase/YqeY domain fusion protein,0.5482,46,3.884487362698484e-29,9.35384556937795e-26,1.0,3.1905500553567744e-28,7.682844533299113e-25,1.0,essential
1164,HNEAP_RS06140,WP_012824091.1,502586332.0,1322128,1323432,1304.0,-,pyridine nucleotide-disulfide oxidoreductase,0.5241,29,0.27777797176505065,668.889356010242,47.0,0.35594098369553523,857.1058887388489,47.0,nonessential
1165,HNEAP_RS06145,WP_012824092.1,502586333.0,1323758,1324702,944.0,-,sulfur oxidation protein,0.473,30,0.7538426056267762,1815.252994349277,41.0,0.8510891359775946,2049.422639434048,42.0,nonessential
1166,HNEAP_RS06150,WP_012824093.1,502586334.0,1324918,1325568,650.0,-,ribonuclease HII,0.51,18,0.7757607812424934,1868.031961231924,29.0,0.765749947884749,1843.9258745064758,28.0,nonessential
1167,HNEAP_RS06155,WP_012824094.1,502586335.0,1325613,1326848,1235.0,+,lipid-A-disaccharide synthase,0.5704,19,2.572985751945447e-19,6.195749690684636e-16,2.0,1.8827755843150174e-17,4.533723607030562e-14,3.0,essential
1168,HNEAP_RS06160,WP_012824095.1,502586336.0,1326853,1327638,785.0,-,acetylornithine deacetylase,0.57,14,0.19937868068338244,480.1038630855849,26.0,0.1923348029600943,463.1422055279071,25.0,nonessential
1169,HNEAP_RS06165,WP_012824096.1,502586337.0,1327667,1328404,737.0,-,ATPase AAA,0.5921,11,0.9791709073639376,2357.843544932362,40.0,0.9865941272765726,2375.718658481987,40.0,nonessential
1170,HNEAP_RS06170,WP_081441114.1,1174219933.0,1328397,1329899,1502.0,-,integrase,0.6094,21,0.9999999999994605,2407.999999998701,120.0,0.9999999999999274,2407.9999999998254,120.0,nonessential
1171,HNEAP_RS06175,WP_081441184.1,1174220003.0,1330002,1330379,377.0,-,hypothetical protein,0.5608,6,0.8264451086283974,1990.0798215771808,18.0,0.8565151058409958,2062.4883748651177,18.0,nonessential
1172,HNEAP_RS06180,WP_041600804.1,753845187.0,1330410,1332635,2225.0,-,DNA topoisomerase IV subunit A,0.5764,36,4.2438790075441587e-32,1.0219260650166334e-28,5.0,1.0507852874272705e-36,2.5302909721248672e-33,1.0,essential
1173,HNEAP_RS06185,WP_012824100.1,502586341.0,1332702,1333832,1130.0,-,LPS export ABC transporter permease LptG,0.5411,30,1.3846568080049536e-08,3.334253593675929e-05,13.0,6.598718149298726e-10,1.5889713303511332e-06,10.0,essential
1174,HNEAP_RS06190,WP_012824101.1,502586342.0,1333819,1334934,1115.0,-,LPS export ABC transporter permease LptF,0.5403,28,4.2597110931036507e-16,1.0257384312193591e-12,3.0,1.5496794431017187e-15,3.731628098988939e-12,3.0,essential
1175,HNEAP_RS06195,WP_012824102.1,502586343.0,1334939,1336348,1409.0,-,U32 family peptidase,0.5596,28,2.0131998843448475e-06,0.004847785321502393,25.0,5.3553629070263646e-06,0.012895713880119486,25.0,essential
1176,HNEAP_RS06200,WP_012824103.1,502586344.0,1336544,1336975,431.0,+,BLUF domain-containing protein,0.5255,11,0.9601552418337899,2312.053822335766,24.0,0.9253720947958739,2228.2960042684645,22.0,nonessential
1177,HNEAP_RS12530,WP_012824104.1,502586345.0,1336983,1337165,182.0,+,DUF2256 domain-containing protein,0.5355,3,0.9998698364100399,2407.686566075376,18.0,0.9997387241685122,2407.3708477977775,17.0,nonessential
1178,HNEAP_RS06205,WP_012824105.1,502586347.0,1337175,1338710,1535.0,+,cryptochrome/photolyase family protein,0.5645,36,0.9992400783052564,2406.1701085590576,86.0,0.9977143341214569,2402.496116564468,81.0,nonessential
1179,HNEAP_RS06210,WP_012824106.1,502586348.0,1338734,1340080,1346.0,-,UDP-glucose/GDP-mannose dehydrogenase family protein,0.5338,22,2.121759561181058e-24,5.1091970233239875e-21,0.0,1.1287379739770748e-23,2.718001041336796e-20,0.0,essential
1180,HNEAP_RS06215,WP_012824107.1,502586349.0,1340108,1340680,572.0,-,DUF615 domain-containing protein,0.555,12,0.13034234379461385,313.86436385743013,17.0,0.22627839301445388,544.8783703788049,18.0,nonessential
1181,HNEAP_RS06220,WP_012824108.1,502586350.0,1340703,1342544,1841.0,-,glutamine--fructose-6-phosphate transaminase (isomerizing),0.5532,37,4.1753144311768056e-33,1.0054157150273748e-29,0.0,4.107138506730249e-32,9.88998952420644e-29,0.0,essential
1182,HNEAP_RS06225,WP_012824109.1,502586351.0,1342584,1343864,1280.0,-,glutamate-1-semialdehyde-2 1-aminomutase,0.5699,23,3.072536839424766e-23,7.398668709334837e-20,0.0,1.5059144751169504e-22,3.6262420560816167e-19,0.0,essential
1183,HNEAP_RS06230,WP_012824110.1,502586352.0,1344050,1344700,650.0,-,thiamine phosphate synthase,0.5315,14,1.3325808702880329e-08,3.208854735653583e-05,3.0,3.025870595752916e-09,7.2862963945730215e-06,2.0,essential
1184,HNEAP_RS06235,WP_012824111.1,502586353.0,1344700,1345716,1016.0,-,glucokinase,0.5497,25,0.02407918224499836,57.98267084595605,28.0,0.03680578569767038,88.62833195999028,28.0,nonessential
1185,HNEAP_RS06240,WP_012824112.1,502586354.0,1345713,1348922,3209.0,-,phosphorylase kinase alphabeta,0.5523,50,0.9868002374750316,2376.2149718398764,152.0,0.9705461215572234,2337.075060709794,144.0,nonessential
1186,HNEAP_RS06245,WP_012824113.1,502586355.0,1348932,1349885,953.0,-,Hsp33 protein,0.5891,7,0.9989063233855934,2405.3664267125087,57.0,0.9985390644404729,2404.482067172659,55.0,nonessential
1187,HNEAP_RS06250,WP_012824114.1,502586356.0,1349882,1351360,1478.0,-,Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase GatCAB subunit B,0.57,33,1.94918050606431e-23,4.693626658602859e-20,2.0,1.1476307737247499e-22,2.7634949031291975e-19,2.0,essential
1188,HNEAP_RS06255,WP_012824115.1,502586357.0,1351357,1352829,1472.0,-,Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase GatCAB subunit A,0.5757,33,7.977436041712146e-25,1.920966598844285e-21,1.0,4.8099655247547716e-24,1.158239698360949e-20,1.0,essential
1189,HNEAP_RS06260,WP_012824117.1,502586359.0,1352955,1353242,287.0,-,Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase GatCAB subunit C,0.5278,3,8.959313636713799e-06,0.021574027237206826,0.0,1.2795393982395699e-05,0.030811308709608843,0.0,essential
1190,HNEAP_RS06265,WP_012824118.1,502586360.0,1353847,1354884,1037.0,+,rod shape-determining protein,0.5723,19,5.772382101561005e-19,1.3899896100558902e-15,0.0,2.0922256911346512e-18,5.0380794642522404e-15,0.0,essential
1191,HNEAP_RS06270,WP_012824119.1,502586361.0,1354900,1355901,1001.0,+,rod shape-determining protein MreC,0.524,18,3.140834809705305e-14,7.563130221770374e-11,3.0,9.92054065979893e-14,2.3888661908795823e-10,3.0,essential
1192,HNEAP_RS06275,WP_012824120.1,502586362.0,1355891,1356358,467.0,+,rod shape-determining protein MreD,0.515,15,0.021276593385049156,51.23403687119837,10.0,0.014140374244640057,34.05002118109326,9.0,nonessential
1193,HNEAP_RS06280,WP_012824121.1,502586363.0,1356381,1356755,374.0,-,diacylglycerol kinase,0.528,9,0.2758500223599333,664.2468538427194,12.0,0.3161420620810513,761.2700854911715,12.0,nonessential
1194,HNEAP_RS06285,WP_012824122.1,502586364.0,1356765,1357136,371.0,-,glycine cleavage system protein H,0.5081,5,0.9750805798401293,2347.9940362550315,22.0,0.9816734539311855,2363.8696770662946,22.0,nonessential
1195,HNEAP_RS06290,WP_012824123.1,502586365.0,1357377,1358339,962.0,-,sigma-54-dependent Fis family transcriptional regulator,0.5171,20,0.9517688387728086,2291.8593637649233,48.0,0.9397411458653244,2262.8966792437013,46.0,nonessential
1196,HNEAP_RS06295,WP_012824124.1,502586366.0,1358402,1358641,239.0,+,alkylphosphonate utilization operon protein PhnA,0.4875,9,0.7568347300470377,1822.4580299532668,11.0,0.6839137982496903,1646.8644261852544,10.0,nonessential
1197,HNEAP_RS06300,WP_012824125.1,502586367.0,1358670,1359215,545.0,-,peroxiredoxin,0.4762,16,0.9993007839729241,2406.316287806801,37.0,0.9985690113559311,2404.554179345082,35.0,nonessential
1198,HNEAP_RS06305,WP_012824126.1,502586368.0,1359422,1359832,410.0,+,large-conductance mechanosensitive channel protein MscL,0.4915,11,0.00756553561842063,18.217809769156876,7.0,0.004067995686985526,9.795733614261147,6.0,nonessential
1199,HNEAP_RS06310,WP_049772483.1,908628450.0,1359881,1360858,977.0,-,aldo/keto reductase,0.5164,28,0.0011225059991698356,2.702994446000964,21.0,0.003662202673937171,8.818584038840708,22.0,nonessential
1200,HNEAP_RS06315,WP_012824128.1,502586370.0,1361161,1361694,533.0,+,hypothetical protein,0.5281,10,8.802510463892689e-05,0.21196445197053596,6.0,0.00014251913115573972,0.34318606782302125,6.0,nonessential
1201,HNEAP_RS12250,WP_012824129.1,502586371.0,1361810,1364023,2213.0,-,GGDEF domain-containing protein,0.5226,40,0.9292044312837886,2237.524270531363,101.0,0.8717739435228862,2099.23165600311,95.0,nonessential
1202,HNEAP_RS06325,WP_012824130.1,502586372.0,1364203,1365474,1271.0,+,diguanylate cyclase,0.5102,34,0.003181633622573358,7.661373763156646,32.0,0.0035863627117094167,8.635961409796275,31.0,nonessential
1203,HNEAP_RS06330,WP_012824131.1,502586374.0,1365504,1367051,1547.0,-,SulP family inorganic anion transporter,0.522,31,7.629921776176992e-05,0.18372851637034196,34.0,5.226099986298223e-05,0.1258444876700612,32.0,nonessential
1204,HNEAP_RS06335,WP_012824132.1,502586375.0,1367148,1367597,449.0,-,MazG nucleotide pyrophosphohydrolase,0.5289,6,0.14679221170587325,353.4756457877428,13.0,0.177613734920712,427.6938736890745,13.0,nonessential
1205,HNEAP_RS06340,WP_012824133.1,502586376.0,1367594,1368607,1013.0,-,lipoyl synthase,0.5828,15,0.0001243373825860657,0.2994044172672462,19.0,2.7661283478925873e-06,0.006660837061725351,14.0,ambiguous
1206,HNEAP_RS06345,WP_012824134.1,502586377.0,1368649,1369284,635.0,-,lipoyl(octanoyl) transferase LipB,0.5204,18,0.00015559944473933783,0.3746834629323255,9.0,1.6043343026686626e-06,0.0038632370008261393,5.0,ambiguous
1207,HNEAP_RS06350,WP_012824135.1,502586378.0,1369331,1369669,338.0,-,DUF493 domain-containing protein,0.531,2,0.07805300628104286,187.9516391247512,8.0,0.02370241522016762,57.07541585016363,6.0,nonessential
1208,HNEAP_RS06355,WP_012824136.1,502586379.0,1369669,1370526,857.0,-,class IV aminotransferase,0.5536,24,0.8322391238402287,2004.0318102072706,39.0,0.8365574190076762,2014.4302649704844,38.0,nonessential
1209,HNEAP_RS06360,WP_012824137.1,502586380.0,1370526,1371803,1277.0,-,serine hydrolase,0.507,39,9.268220420340278e-12,2.231787477217939e-08,11.0,1.3100557540603258e-12,3.1546142557772646e-09,9.0,essential
1210,HNEAP_RS06365,WP_012824138.1,502586381.0,1371800,1372654,854.0,-,septal ring lytic transglycosylase RlpA family lipoprotein,0.5614,19,0.5528310322889042,1331.2171257516814,34.0,0.4135001091299468,995.7082627849119,31.0,nonessential
1211,HNEAP_RS06370,WP_012824139.1,502586382.0,1372651,1373796,1145.0,-,lytic murein transglycosylase B,0.5489,27,0.9859136868996513,2374.0801580543603,60.0,0.9681069004819292,2331.2014163604854,56.0,nonessential
1212,HNEAP_RS06380,WP_012824141.1,502586384.0,1374991,1376874,1883.0,-,penicillin-binding protein 2,0.5409,45,1.223089316199434e-27,2.9451990734082372e-24,4.0,1.7060176835607965e-25,4.108090582014398e-22,5.0,essential
1213,HNEAP_RS06385,WP_012824142.1,502586385.0,1376946,1377476,530.0,-,inorganic diphosphatase,0.548,9,1.0922785951494618e-08,2.630206857119904e-05,1.0,2.0463362618924684e-08,4.927577718637064e-05,1.0,essential
1214,HNEAP_RS06390,WP_012824143.1,502586386.0,1377654,1378307,653.0,+,adenylate kinase,0.5474,13,9.163757090966485e-11,2.2066327075047296e-07,1.0,1.999585356022249e-10,4.815001537301575e-07,1.0,essential
1215,HNEAP_RS06395,WP_012824144.1,502586387.0,1378325,1380661,2336.0,+,LPS-assembly protein LptD,0.5571,58,8.216411943250173e-42,1.9785119959346417e-38,0.0,1.4944643577490721e-40,3.5986701734597657e-37,0.0,essential
1216,HNEAP_RS06400,WP_012824145.1,502586388.0,1380777,1382174,1397.0,+,SurA domain-containing protein,0.5429,26,1.579867946099362e-23,3.8043220142072636e-20,1.0,1.5244559061661701e-24,3.670889822048137e-21,0.0,essential
1217,HNEAP_RS06405,WP_041600387.1,753844770.0,1382186,1383214,1028.0,+,4-hydroxythreonine-4-phosphate dehydrogenase PdxA,0.6093,14,8.310862696897389e-19,2.0012557374128913e-15,0.0,2.9788310509482397e-18,7.173025170683361e-15,0.0,essential
1218,HNEAP_RS06410,WP_012824147.1,502586390.0,1383214,1384071,857.0,+,16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA,0.5513,13,0.4053600565972292,976.1070162861279,32.0,0.2733350049596389,658.1906919428105,29.0,nonessential
1219,HNEAP_RS06415,WP_081441115.1,1174219934.0,1384076,1384867,791.0,+,6-phosphogluconolactonase,0.5328,22,0.9743627287428802,2346.2654508128558,42.0,0.9892001938884292,2381.9940668833374,43.0,nonessential
1220,HNEAP_RS06420,WP_012824149.1,502586392.0,1384868,1385296,428.0,+,Co2+/Mg2+ efflux protein ApaG,0.5221,10,0.004825644549877644,11.620152076105366,7.0,0.015402752425650684,37.08982784096685,8.0,nonessential
1221,HNEAP_RS06425,WP_012824150.1,502586393.0,1385302,1385916,614.0,+,class I SAM-dependent methyltransferase,0.548,13,0.9486664407986636,2284.388789443182,32.0,0.9455179900324489,2276.807319998137,31.0,nonessential
1222,HNEAP_RS06430,WP_012824151.1,502586394.0,1385937,1386800,863.0,+,symmetrical bis(5'-nucleosyl)-tetraphosphatase,0.5532,14,0.9998301102425068,2407.5909054639565,56.0,0.9995663816553291,2406.955847026032,53.0,nonessential
1223,HNEAP_RS06435,WP_012824152.1,502586395.0,1386769,1387446,677.0,-,glutathione S-transferase,0.5147,12,0.9663529462380395,2326.977894541199,36.0,0.9772022957410794,2353.1031281445194,36.0,nonessential
1224,HNEAP_RS06440,WP_012824153.1,502586396.0,1387607,1388662,1055.0,+,phosphoribosylformylglycinamidine cyclo-ligase,0.5758,16,1.2420140965728253e-17,2.9907699445473634e-14,1.0,4.462773618256525e-17,1.0746358872761713e-13,1.0,essential
1225,HNEAP_RS06445,WP_012824154.1,502586397.0,1388676,1389338,662.0,+,phosphoribosylglycinamide formyltransferase,0.5354,15,0.23022436770872912,554.3802774426197,22.0,0.07378966363597853,177.6855100354363,18.0,nonessential
1226,HNEAP_RS06450,WP_012824155.1,502586398.0,1389354,1390256,902.0,-,cysteine synthase CysM,0.5415,23,5.232108285710491e-15,1.2598916751990863e-11,1.0,1.554870159210797e-14,3.7441273433795996e-11,1.0,essential
1227,HNEAP_RS06455,WP_012824156.1,502586399.0,1390383,1392578,2195.0,+,response regulator receiver and Hpt phospho transfer protein,0.5128,52,0.9989513679391424,2405.4748939974547,116.0,0.9996374552201489,2407.1269921701187,116.0,nonessential
1228,HNEAP_RS12535,WP_012824157.1,502586400.0,1392519,1392773,254.0,-,hypothetical protein,0.5098,9,0.973829841343313,2344.9822579546976,16.0,0.8844317265569053,2129.711597549028,13.0,nonessential
1229,HNEAP_RS06460,WP_081441116.1,1174219935.0,1392804,1394048,1244.0,+,hypothetical protein,0.5076,32,0.7302903201577887,1758.5390909399553,53.0,0.6021303259507269,1449.9298248893504,49.0,nonessential
1230,HNEAP_RS12255,WP_049772485.1,908628452.0,1394073,1394483,410.0,+,EAL domain-containing protein,0.5036,9,0.8569507659224282,2063.5374443412074,20.0,0.8843501903077741,2129.51525826112,20.0,nonessential
1231,HNEAP_RS06465,WP_012824158.1,502586401.0,1394881,1395288,407.0,+,PilZ domain-containing protein,0.402,17,0.9979781193946909,2403.131311502416,28.0,0.9993664194857285,2406.474338121634,29.0,nonessential
1232,HNEAP_RS06470,WP_012824159.1,502586402.0,1395345,1396406,1061.0,+,diguanylate cyclase,0.5151,19,0.9987401606991116,2404.9663069634607,62.0,0.999630778487003,2407.1109145967034,63.0,nonessential
1233,HNEAP_RS06475,WP_012824160.1,502586403.0,1396563,1397117,554.0,+,PAS domain S-box protein,0.5153,15,0.7157120882326182,1723.4347084641447,24.0,0.5288582021134505,1273.4905506891887,21.0,nonessential
1234,HNEAP_RS06480,WP_012824161.1,502586405.0,1397635,1399407,1772.0,+,thiol reductant ABC exporter subunit CydD,0.5386,37,0.2419895858928355,582.7109228299479,64.0,0.2051886100603929,494.09417302542613,61.0,nonessential
1235,HNEAP_RS06485,WP_012824162.1,502586406.0,1399404,1401092,1688.0,+,thiol reductant ABC exporter subunit CydC,0.5465,32,0.9216567662472247,2219.349493123317,78.0,0.940329736542698,2264.314005594817,77.0,nonessential
1236,HNEAP_RS06490,WP_012824163.1,502586407.0,1401422,1402873,1451.0,+,cytochrome ubiquinol oxidase subunit I,0.5379,26,0.5035244053666794,1212.4867681229641,57.0,0.32950553744872985,793.4493341765415,52.0,nonessential
1237,HNEAP_RS06495,WP_012824164.1,502586408.0,1402895,1403941,1046.0,+,cytochrome d ubiquinol oxidase subunit II,0.5454,24,0.216121780890281,520.4212483837966,36.0,0.17779028929700857,428.11901662719663,34.0,nonessential
1238,HNEAP_RS06500,WP_012824166.1,502586410.0,1404450,1405211,761.0,+,DUF1461 domain-containing protein,0.5052,22,0.9986424791815119,2404.7310898690807,47.0,0.9992702937525196,2406.242867356067,47.0,nonessential
1239,HNEAP_RS06505,WP_012824167.1,502586411.0,1405305,1406948,1643.0,-,alpha-D-glucose phosphate-specific phosphoglucomutase,0.5426,34,0.8785748641994785,2115.608272992344,74.0,0.88090528116998,2121.2199170573117,72.0,nonessential
1240,HNEAP_RS06510,WP_012824168.1,502586412.0,1407248,1408462,1214.0,+,hypothetical protein,0.4642,32,0.7854740310090471,1891.4214666697856,53.0,0.8437102950640419,2031.654390514213,53.0,nonessential
1241,HNEAP_RS06515,WP_081441185.1,1174220004.0,1408547,1409131,584.0,-,lytic transglycosylase domain-containing protein,0.535,11,0.8218298814595726,1978.9663545546507,27.0,0.8590683629796858,2068.6366180550835,27.0,nonessential
1242,HNEAP_RS06520,WP_081441117.1,1174219936.0,1409286,1409723,437.0,+,DUF1249 domain-containing protein,0.4658,14,0.03886041036941367,93.57586816954812,10.0,0.05011209574902865,120.66992656366098,10.0,nonessential
1243,HNEAP_RS06525,WP_012824171.1,502586415.0,1409778,1410230,452.0,+,Rrf2 family transcriptional regulator,0.5166,11,0.9376334534278814,2257.8213558543384,24.0,0.9529246234357923,2294.642493233388,24.0,nonessential
1244,HNEAP_RS06540,WP_012824172.1,502586416.0,1410747,1411487,740.0,-,DUF429 domain-containing protein,0.5412,14,0.4461711651775254,1074.3801657474812,28.0,0.43649990363185354,1051.0917679455033,27.0,nonessential
1245,HNEAP_RS06545,WP_012824173.1,502586417.0,1411644,1412345,701.0,+,short-chain dehydrogenase,0.567,12,0.9937906161199561,2393.0478036168543,41.0,0.990129389784964,2384.231570602193,39.0,nonessential
1246,HNEAP_RS06550,WP_012824174.1,502586418.0,1412342,1412560,218.0,+,TIGR03643 family protein,0.5434,5,0.5004946107137381,1205.1910225986815,8.0,0.396095524677223,953.798023422753,7.0,nonessential
1247,HNEAP_RS06555,WP_012824175.1,502586419.0,1412557,1414080,1523.0,+,deoxyribodipyrimidine photo-lyase,0.5558,26,0.8544116599667672,2057.4232771999755,68.0,0.8209460690693124,1976.8381343189044,65.0,nonessential
1248,HNEAP_RS06560,WP_012824176.1,502586420.0,1414491,1416107,1616.0,+,MFS transporter,0.5591,32,0.9524852574773821,2293.584500005536,77.0,0.8837180965731326,2127.9931765481033,71.0,nonessential
1249,HNEAP_RS06565,WP_012824177.1,502586421.0,1416193,1417419,1226.0,-,hypothetical protein,0.5249,35,0.04694625882052055,113.0465912398135,37.0,0.025448481456906362,61.27994334823052,34.0,nonessential
1250,HNEAP_RS06570,WP_012824178.1,502586422.0,1417441,1420743,3302.0,-,IMP dehydrogenase,0.5601,61,0.015755139715773456,37.938376435582484,107.0,0.028582871092025872,68.8275535895983,106.0,nonessential
1251,HNEAP_RS06575,WP_012824179.1,502586423.0,1420740,1421543,803.0,-,peptidase,0.5025,17,0.6903303556969933,1662.3154965183599,34.0,0.7499303355002754,1805.8322478846633,34.0,nonessential
1252,HNEAP_RS06580,WP_041600389.1,753844772.0,1421572,1422567,995.0,-,alpha-E domain-containing protein,0.5181,32,0.9934008553349978,2392.1092596466747,55.0,0.9976764413109434,2402.4048706767517,56.0,nonessential
1253,HNEAP_RS06585,WP_041600829.1,753845212.0,1422579,1424012,1433.0,-,circularly permuted type 2 ATP-grasp protein,0.5223,42,0.9852089523229046,2372.3831571935543,73.0,0.9945295546057991,2394.827167490764,74.0,nonessential
1254,HNEAP_RS06590,WP_012824182.1,502586426.0,1424534,1425055,521.0,-,MerR family transcriptional regulator,0.5077,17,6.866063307758269e-10,1.6533480445081913e-06,0.0,1.3112417886641569e-09,3.1574702271032897e-06,0.0,essential
1255,HNEAP_RS06595,WP_012824183.1,502586427.0,1425033,1425335,302.0,-,integration host factor subunit alpha,0.5215,5,0.006848088519282127,16.490197154431364,4.0,0.008880344230399006,21.383868906800807,4.0,nonessential
1256,HNEAP_RS06600,WP_012824184.1,502586428.0,1425349,1427748,2399.0,-,phenylalanine--tRNA ligase subunit beta,0.5383,37,6.40685585388405e-43,1.5427708896152793e-39,0.0,1.260155591175333e-41,3.034454663550202e-38,0.0,essential
1257,HNEAP_RS06605,WP_041600830.1,753845213.0,1427790,1428812,1022.0,-,phenylalanine--tRNA ligase subunit alpha,0.5591,19,1.0596768940555314e-18,2.5517019608857197e-15,0.0,3.769965998327436e-18,9.078078123972465e-15,0.0,essential
1258,HNEAP_RS06610,WP_012824186.1,502586430.0,1429035,1429394,359.0,-,50S ribosomal protein L20,0.5194,13,6.094447056624419e-05,0.14675428512351602,2.0,1.1649754748075947e-05,0.02805260943336688,1.0,ambiguous
1259,HNEAP_RS06615,WP_012824187.1,502586431.0,1429408,1429602,194.0,-,50S ribosomal protein L35,0.5077,4,0.0003872119741975619,0.932406433867729,0.0,0.0004926889920920134,1.1863950929575682,0.0,ambiguous
1260,HNEAP_RS06620,WP_012824188.1,502586433.0,1429916,1430488,572.0,-,translation initiation factor IF-3,0.5166,11,2.1447050903073017e-09,5.164449857459983e-06,1.0,4.232711582260974e-09,1.0192369490084426e-05,1.0,essential
1261,HNEAP_RS06625,WP_012824189.1,502586434.0,1430827,1432740,1913.0,-,threonine--tRNA ligase,0.5423,39,1.810454555100782e-32,4.3595745686826833e-29,1.0,1.8873207038524191e-31,4.544668254876625e-28,1.0,essential
1262,HNEAP_RS06630,WP_012824190.1,502586435.0,1433091,1433813,722.0,+,DUF484 domain-containing protein,0.5145,17,0.9997494367202572,2407.396643622379,48.0,0.9999340810841206,2407.8412672505624,49.0,nonessential
1263,HNEAP_RS06635,WP_012824191.1,502586436.0,1433813,1434802,989.0,+,integrase family protein,0.5384,19,0.9941289440886438,2393.862497365454,55.0,0.995048847634817,2396.0776251046395,54.0,nonessential
1264,HNEAP_RS06640,WP_012824192.1,502586437.0,1434885,1435424,539.0,+,ATP-dependent protease subunit HslV,0.5704,8,0.8687395498431547,2091.9248360223164,26.0,0.8978335249943235,2161.9831281863308,26.0,nonessential
1265,HNEAP_RS06645,WP_012824193.1,502586438.0,1435421,1436761,1340.0,+,ATP-dependent protease ATPase subunit HslU,0.5623,20,0.8469926702689624,2039.5583500076614,60.0,0.7160471642019608,1724.2415713983216,55.0,nonessential
1266,HNEAP_RS06650,WP_012824194.1,502586439.0,1436777,1437199,422.0,+,DUF971 domain-containing protein,0.5579,8,0.9480446623449987,2282.8915469267567,23.0,0.9042097606483948,2177.3371036413346,21.0,nonessential
1267,HNEAP_RS06655,WP_012824195.1,502586440.0,1437225,1437968,743.0,+,bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1 4-benzoquinol methylase UbiE,0.543,16,8.554518730201913e-14,2.0599281102326208e-10,0.0,2.1522614276891275e-13,5.182645517875419e-10,0.0,essential
1268,HNEAP_RS06660,WP_041600390.1,753844773.0,1438168,1439565,1397.0,+,lytic transglycosylase F,0.515,44,1.895692780636463e-13,4.564828215772603e-10,11.0,4.130790936599303e-15,9.946944575331121e-12,8.0,essential
1269,HNEAP_RS06665,WP_012824197.1,502586442.0,1439613,1440329,716.0,-,orotidine-5'-phosphate decarboxylase,0.583,9,7.810316908849544e-12,1.8807243116509702e-08,1.0,6.211651002460536e-13,1.4957655613924971e-09,0.0,essential
1270,HNEAP_RS06670,WP_012824198.1,502586443.0,1440339,1440644,305.0,-,integration host factor subunit beta,0.4837,10,4.32207867457261e-06,0.010407565448370846,0.0,6.312174255325463e-06,0.015199715606823715,0.0,essential
1271,HNEAP_RS06675,WP_012824199.1,502586444.0,1440826,1442508,1682.0,-,30S ribosomal protein S1,0.5282,25,8.05465075405271e-17,1.9395599015758926e-13,12.0,7.879100149430862e-17,1.8972873159829516e-13,11.0,essential
1272,HNEAP_RS06680,WP_012824200.1,502586445.0,1442623,1443282,659.0,-,(d)CMP kinase,0.5773,11,2.567902821241334e-12,6.183509993549132e-09,0.0,5.820722261760298e-12,1.4016299206318799e-08,0.0,essential
1273,HNEAP_RS06685,WP_012824201.1,502586446.0,1443279,1444649,1370.0,-,3-phosphoshikimate 1-carboxyvinyltransferase,0.5784,25,4.6255539730374063e-23,1.1138333967074073e-19,1.0,2.4572561176135255e-22,5.917072731213369e-19,1.0,essential
1274,HNEAP_RS06690,WP_012824202.1,502586447.0,1444675,1445553,878.0,-,prephenate dehydrogenase/arogenate dehydrogenase family protein,0.5791,15,3.322515476792615e-08,8.000617268116617e-05,8.0,7.731998884802541e-08,0.00018618653314604518,8.0,essential
1275,HNEAP_RS06695,WP_012824203.1,502586448.0,1445563,1446747,1184.0,-,histidinol-phosphate transaminase,0.5662,31,2.813960174514561e-09,6.7760161002310625e-06,13.0,9.080579851259025e-08,0.00021866036281831732,15.0,essential
1276,HNEAP_RS06700,WP_012824204.1,502586449.0,1446744,1447985,1241.0,-,chorismate mutase,0.5757,19,4.837106260214092e-16,1.1647751874595534e-12,5.0,1.6304023441800186e-14,3.926008844785485e-11,6.0,essential
1277,HNEAP_RS06705,WP_012824205.1,502586450.0,1447996,1449159,1163.0,-,3-phosphoglycerate dehydrogenase,0.5378,23,1.7220913436269196e-19,4.1467959554536226e-16,1.0,7.075388267357784e-19,1.7037534947797545e-15,1.0,essential
1278,HNEAP_RS06710,WP_012824206.1,502586451.0,1449219,1450310,1091.0,-,3-phosphoserine/phosphohydroxythreonine transaminase,0.5321,25,6.480505077911278e-20,1.5605056227610356e-16,0.0,2.5117966745443105e-19,6.048406392302699e-16,0.0,essential
1279,HNEAP_RS06715,WP_012824207.1,502586452.0,1450363,1452957,2594.0,-,DNA gyrase subunit A,0.5487,52,2.3823515002680463e-46,5.736702412645455e-43,0.0,5.969644049519665e-45,1.4374902871243354e-41,0.0,essential
1280,HNEAP_RS06720,WP_012824208.1,502586453.0,1453477,1454100,623.0,+,OmpA family protein,0.5192,14,0.006583565431156562,15.853225558225002,13.0,0.0003550689042406813,0.8550059214115605,9.0,nonessential
1281,HNEAP_RS06725,WP_012824210.1,502586455.0,1454459,1455259,800.0,+,mechanosensitive ion channel protein,0.5169,20,0.35044746955775513,843.8775066950743,29.0,0.41635083117150984,1002.5728014609957,29.0,nonessential
1282,HNEAP_RS06730,WP_081441118.1,1174219937.0,1455294,1456142,848.0,-,hypothetical protein,0.5383,15,0.03166220861691864,76.24259834954007,23.0,0.04586427979039982,110.44118573528277,23.0,nonessential
1283,HNEAP_RS06735,WP_012824212.1,502586457.0,1456133,1457455,1322.0,-,amino-acid N-acetyltransferase,0.5601,18,8.676049405390995e-21,2.0891926968181517e-17,2.0,4.2091613819849547e-20,1.0135660607819771e-16,2.0,essential
1284,HNEAP_RS06740,WP_012824213.1,502586458.0,1457540,1458478,938.0,-,ornithine carbamoyltransferase,0.5623,16,3.180947253341539e-17,7.659720986046426e-14,0.0,1.0195752583878705e-16,2.455137222197992e-13,0.0,essential
1285,HNEAP_RS06745,WP_081441119.1,1174219938.0,1458597,1459847,1250.0,-,aspartate aminotransferase family protein,0.5651,19,0.3325932482014244,800.8845416690299,46.0,0.25242687592923446,607.8439172375965,43.0,nonessential
1286,HNEAP_RS06750,WP_012824215.1,502586460.0,1460051,1460764,713.0,+,bifunctional 2-polyprenyl-6-hydroxyphenol methylase/3-demethylubiquinol 3-O-methyltransferase UbiG,0.5238,14,2.8829185213045596e-13,6.942067799301379e-10,0.0,6.987998896336376e-13,1.6827101342377993e-09,0.0,essential
1287,HNEAP_RS06755,WP_012824216.1,502586461.0,1460754,1461455,701.0,+,phosphoglycolate phosphatase,0.5356,18,0.9763798432747809,2351.1226626056723,38.0,0.9644079249870084,2322.294283368716,36.0,nonessential
1288,HNEAP_RS06760,WP_012824217.1,502586462.0,1461476,1462054,578.0,+,hypothetical protein,0.5337,15,0.9980127333590808,2403.2146619286664,37.0,0.9988251915779721,2405.171061319757,37.0,nonessential
1289,HNEAP_RS06765,WP_012824218.1,502586463.0,1462085,1462267,182.0,-,hypothetical protein,0.4699,1,0.14821542579394564,356.9027453118211,4.0,0.07742325292829512,186.43519305133464,3.0,nonessential
1290,HNEAP_RS06770,WP_012824219.1,502586464.0,1462466,1462735,269.0,-,hypothetical protein,0.4963,6,0.9882192209966617,2379.6318841599614,18.0,0.9912517069380964,2386.934110306936,18.0,nonessential
1291,HNEAP_RS06775,WP_012824220.1,502586465.0,1462878,1464254,1376.0,-,dihydroorotase,0.5839,21,3.643354207906204e-23,8.773196932638139e-20,1.0,3.476444743905828e-24,8.371278943325235e-21,0.0,essential
1292,HNEAP_RS06780,WP_012824221.1,502586467.0,1464251,1465252,1001.0,-,aspartate carbamoyltransferase catalytic subunit,0.5629,17,1.0509433854408119e-16,2.5306716721414753e-13,1.0,9.92054065979893e-14,2.3888661908795823e-10,3.0,essential
1293,HNEAP_RS06785,WP_012824222.1,502586468.0,1465252,1465776,524.0,-,bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase,0.5486,11,0.3127123231384532,753.0112741173954,18.0,0.4530553708585024,1090.9573330272738,19.0,nonessential
1294,HNEAP_RS06790,WP_012824223.1,502586469.0,1465779,1466276,497.0,-,Holliday junction resolvase RuvX,0.5522,7,1.6324588498332688e-05,0.039309609103985114,4.0,2.683407232351464e-05,0.06461644615502325,4.0,ambiguous
1295,HNEAP_RS06795,WP_012824224.1,502586470.0,1466294,1466944,650.0,-,YqgE/AlgH family protein,0.5407,12,0.8725215241639359,2101.031830186758,31.0,0.9531148034852024,2295.100446792367,33.0,nonessential
1296,HNEAP_RS06805,WP_012824226.1,502586472.0,1468270,1469511,1241.0,+,hypothetical protein,0.5588,23,0.9999995893909681,2407.999011253451,86.0,0.9999992200408198,2407.998121858294,83.0,nonessential
1297,HNEAP_RS06810,WP_012824227.1,502586473.0,1469513,1470373,860.0,+,iron ABC transporter ATP-binding protein,0.5412,15,0.6684696910629544,1609.6750160795941,36.0,0.7320343710012724,1762.7387653710641,36.0,nonessential
1298,HNEAP_RS06815,WP_012824228.1,502586474.0,1470373,1471377,1004.0,+,MCE family protein,0.5005,26,0.8898994950933963,2142.877984184898,47.0,0.8683539772256272,2090.99637715931,45.0,nonessential
1299,HNEAP_RS06820,WP_012824229.1,502586475.0,1471403,1472059,656.0,+,hypothetical protein,0.5266,11,0.9999999997887147,2407.999999491225,62.0,0.9999999998306361,2407.9999995921717,61.0,nonessential
1300,HNEAP_RS06825,WP_012824230.1,502586476.0,1472317,1473726,1409.0,+,RNA helicase,0.6035,19,0.9997960922368093,2407.508990106237,83.0,0.9996868766597732,2407.2459989967338,80.0,nonessential
1301,HNEAP_RS06830,WP_012824231.1,502586477.0,1473952,1476351,2399.0,-,phosphoenolpyruvate synthase,0.5654,45,0.9998467030157198,2407.6308608618533,131.0,0.9998063331913627,2407.5336503248013,127.0,nonessential
1302,HNEAP_RS06835,WP_012824232.1,502586478.0,1476675,1477490,815.0,+,septum site-determining protein MinD,0.5343,11,0.007088176009965143,17.068327831996065,19.0,0.0032796762739326817,7.897460467629897,17.0,nonessential
1303,HNEAP_RS06840,WP_012824233.1,502586479.0,1477493,1477759,266.0,+,cell division topological specificity factor MinE,0.5019,7,2.0971065216465772e-05,0.05049832504124958,0.0,2.9179250102531387e-05,0.07026363424689558,0.0,ambiguous
1304,HNEAP_RS06845,WP_012824234.1,502586480.0,1477905,1478453,548.0,+,hypothetical protein,0.5811,8,0.9256445814713616,2228.952152183039,28.0,0.7796564774527499,1877.4127977062217,24.0,nonessential
1305,HNEAP_RS06850,WP_012824235.1,502586481.0,1478456,1478929,473.0,+,hypothetical protein,0.5527,10,0.9848896154944417,2371.6141941106157,28.0,0.9536329511019701,2296.348146253544,25.0,nonessential
1306,HNEAP_RS06855,WP_012824236.1,502586482.0,1478933,1479355,422.0,+,RNA-binding S4 domain-containing protein,0.5508,9,0.9194491872306477,2214.0336428513997,22.0,0.9042097606483948,2177.3371036413346,21.0,nonessential
1307,HNEAP_RS06860,WP_012824237.1,502586483.0,1479517,1479996,479.0,+,type II 3-dehydroquinate dehydratase,0.5563,13,2.9420925173106622e-05,0.07084558781684075,4.0,4.73059308711422e-05,0.11391268153771042,4.0,nonessential
1308,HNEAP_RS06865,WP_012824238.1,502586484.0,1480040,1480492,452.0,+,acetyl-CoA carboxylase biotin carboxyl carrier protein subunit,0.5143,6,1.1227224657462942e-08,2.7035156975170765e-05,0.0,1.9680482138335263e-08,4.739060098911131e-05,0.0,essential
1309,HNEAP_RS06870,WP_012824239.1,502586485.0,1480519,1481862,1343.0,+,acetyl-CoA carboxylase biotin carboxylase subunit,0.5476,27,2.3958512270206384e-24,5.769209754665697e-21,0.0,1.2698105082336951e-23,3.057703703826738e-20,0.0,essential
1310,HNEAP_RS06875,WP_012824240.1,502586486.0,1481862,1482773,911.0,+,50S ribosomal protein L11 methyltransferase,0.5537,13,0.09333730768890226,224.75623691487664,28.0,0.16907807138044648,407.13999588411514,29.0,nonessential
1311,HNEAP_RS06880,WP_012824241.1,502586487.0,1482893,1483612,719.0,+,cupin,0.5306,16,0.08495940084395233,204.58223723223722,21.0,0.05054610134948302,121.71501204955511,19.0,nonessential
1312,HNEAP_RS06885,WP_012824242.1,502586488.0,1483635,1484243,608.0,+,nitroreductase family protein,0.5271,11,0.050089237015919344,120.61488273433378,16.0,0.023881708875682705,57.50715497264395,14.0,nonessential
1313,HNEAP_RS06890,WP_012824243.1,502586489.0,1484312,1485316,1004.0,+,NAD(P)-dependent alcohol dehydrogenase,0.5463,23,0.3003597623404358,723.2663077157695,36.0,0.3092836502960795,744.7550299129595,35.0,nonessential
1314,HNEAP_RS06895,WP_041600391.1,753844774.0,1485437,1485658,221.0,+,hypothetical protein,0.6126,4,0.6181617061061658,1488.5333883036474,9.0,0.6532901431762594,1573.1226647684327,9.0,nonessential
1315,HNEAP_RS06900,WP_012824245.1,502586491.0,1485655,1488513,2858.0,-,valine--tRNA ligase,0.5614,55,5.417539865207152e-51,1.3045435995418822e-47,0.0,1.8841685474921017e-49,4.537077862360981e-46,0.0,essential
1316,HNEAP_RS06905,WP_012824246.1,502586492.0,1488562,1489005,443.0,-,DNA polymerase III subunit chi,0.5473,7,0.5070427991923356,1220.9590604551443,17.0,0.6518160856431969,1569.5731342288182,18.0,nonessential
1317,HNEAP_RS06910,WP_012824247.1,502586493.0,1489139,1490101,962.0,+,lysylphosphatidylglycerol synthetase family protein,0.5618,31,7.623889899371793e-11,1.8358326877687276e-07,6.0,1.0055032144560542e-07,0.00024212517404101786,10.0,essential
1318,HNEAP_RS06915,WP_012824248.1,502586494.0,1490157,1490465,308.0,+,antibiotic biosynthesis monooxygenase,0.5307,8,0.9320751111867377,2244.436867737664,17.0,0.9459747888517186,2277.907291554938,17.0,nonessential
1319,HNEAP_RS06920,WP_012824249.1,502586495.0,1490562,1491014,452.0,-,50S ribosomal protein L9,0.5011,10,0.0009196137487704059,2.2144299070391376,6.0,0.00042098874819795147,1.0137409056606672,5.0,nonessential
1320,HNEAP_RS06925,WP_012824250.1,502586496.0,1491042,1491266,224.0,-,30S ribosomal protein S18,0.52,5,0.6021809886120847,1450.0518205779,9.0,0.13553486283271082,326.3679497011677,5.0,nonessential
1321,HNEAP_RS06930,WP_012824251.1,502586497.0,1491297,1491725,428.0,-,30S ribosomal protein S6,0.5524,6,2.967439288505232e-08,7.145593806720598e-05,0.0,5.048960556702721e-08,0.00012157897020540151,0.0,essential
1322,HNEAP_RS06935,WP_012824252.1,502586498.0,1491950,1492342,392.0,-,holo-ACP synthase,0.5496,9,0.08931244662696004,215.0643714777198,10.0,0.0155741651653428,37.50258971814546,7.0,nonessential
1323,HNEAP_RS06940,WP_012824253.1,502586499.0,1492351,1493103,752.0,-,pyridoxine 5'-phosphate synthase,0.5618,11,1.906027548754636e-12,4.589714337401163e-09,1.0,4.702430404320991e-12,1.1323452413604946e-08,1.0,essential
1324,HNEAP_RS06945,WP_012824254.1,502586500.0,1493183,1493908,725.0,-,DNA repair protein RecO,0.5675,13,0.6384183512870529,1537.3113898992235,30.0,0.6307697188952464,1518.8934830997532,29.0,nonessential
1325,HNEAP_RS06950,WP_012824255.1,502586501.0,1493936,1494862,926.0,-,GTPase Era,0.5394,12,3.986118104140437e-14,9.598572394770172e-11,2.0,1.183260450805077e-13,2.849291165538625e-10,2.0,essential
1326,HNEAP_RS06955,WP_012824256.1,502586502.0,1494863,1495594,731.0,-,ribonuclease III,0.5587,9,0.10523554623973362,253.40719534527855,22.0,0.026121543632787795,62.90067706775301,18.0,nonessential
1327,HNEAP_RS06960,WP_012824257.1,502586503.0,1495581,1495961,380.0,-,DUF4845 domain-containing protein,0.4541,13,0.3514531727234048,846.2992399179587,13.0,0.3963978586557208,954.5260436429757,13.0,nonessential
1328,HNEAP_RS06965,WP_012824258.1,502586505.0,1496002,1496802,800.0,-,signal peptidase I,0.4906,31,8.505222642936686e-15,2.048057612419154e-11,0.0,2.2968106454231062e-14,5.53072003417884e-11,0.0,essential
1329,HNEAP_RS06970,WP_012824259.1,502586506.0,1496873,1498681,1808.0,-,elongation factor 4,0.5274,45,0.002435785082033312,5.865370477536215,49.0,0.00011414989349288745,0.274872943530873,41.0,nonessential
1330,HNEAP_RS06975,WP_012824260.1,502586507.0,1498865,1500346,1481.0,-,protease Do,0.554,24,0.9990969002122668,2405.8253357111385,83.0,0.9994292273469635,2406.625579451488,82.0,nonessential
1331,HNEAP_RS06980,WP_041600854.1,753845237.0,1500343,1501656,1313.0,-,homoserine dehydrogenase,0.5647,27,8.074146652204507e-24,1.9442545138508454e-20,0.0,4.122842288550772e-23,9.927804230830259e-20,0.0,essential
1332,HNEAP_RS06985,WP_012824262.1,502586509.0,1501689,1502915,1226.0,-,alanine transaminase,0.5542,30,3.651723509153166e-19,8.793350210040824e-16,2.0,1.5726745625572545e-18,3.787000346637869e-15,2.0,essential
1333,HNEAP_RS06990,WP_012824263.1,502586510.0,1503142,1504329,1187.0,-,threonine synthase,0.5614,16,1.327917632566306e-21,3.197625659219665e-18,0.0,5.798551306375858e-21,1.3962911545753065e-17,0.0,essential
1334,HNEAP_RS06995,WP_012824264.1,502586511.0,1504460,1505227,767.0,-,5'-methylthioadenosine phosphorylase,0.569,18,0.9836306284108237,2368.5825532132635,42.0,0.9841854170396016,2369.9184842313607,41.0,nonessential
1335,HNEAP_RS07000,WP_012824265.1,502586512.0,1505231,1505818,587.0,-,hypoxanthine-guanine phosphoribosyltransferase,0.5714,6,0.6882875947410397,1657.3965281364237,25.0,0.7399284742855805,1781.7477660796778,25.0,nonessential
1336,HNEAP_RS07005,WP_012824266.1,502586513.0,1505825,1506913,1088.0,-,beta-N-acetylhexosaminidase,0.5813,15,0.5292242160428816,1274.3719122312589,43.0,0.48561198697560426,1169.353664637255,41.0,nonessential
1337,HNEAP_RS07010,WP_012824267.1,502586514.0,1507260,1508012,752.0,-,dienelactone hydrolase family protein,0.5671,11,0.9969995763746947,2400.774979910265,45.0,0.9953435197104296,2396.7871954627144,43.0,nonessential
1338,HNEAP_RS07015,WP_012824268.1,502586515.0,1508242,1508451,209.0,-,hypothetical protein,0.5286,3,0.6812895558171814,1640.545250407773,9.0,0.7133371827952444,1717.7159361709485,9.0,nonessential
1339,HNEAP_RS07020,WP_012824269.1,502586516.0,1508769,1509065,296.0,-,DUF1840 domain-containing protein,0.5455,7,0.9919472346550774,2388.6089410494264,20.0,0.9781647567836184,2355.420734334953,18.0,nonessential
1340,HNEAP_RS07025,WP_012824270.1,502586517.0,1509151,1511634,2483.0,-,plasma-membrane proton-efflux P-type ATPase,0.5568,39,0.9999999987212325,2407.999996920728,161.0,0.9999996332272141,2407.9991168111314,146.0,nonessential
1341,HNEAP_RS07030,WP_012824271.1,502586518.0,1511876,1512670,794.0,-,hypothetical protein,0.5824,7,0.9999999432443051,2407.9998633322866,64.0,0.9999997952488657,2407.9995069592687,61.0,nonessential
1342,HNEAP_RS07035,WP_081441120.1,1174219939.0,1512690,1513955,1265.0,-,hypothetical protein,0.5687,20,1.0472299013904502e-05,0.02521729602548204,23.0,1.9339572236877323e-06,0.00465696899464006,20.0,essential
1343,HNEAP_RS07040,WP_012824273.1,502586520.0,1514034,1514414,380.0,+,ModE family transcriptional regulator,0.5669,7,0.3514531727234048,846.2992399179587,13.0,0.29495161752995447,710.2434950121303,12.0,nonessential
1344,HNEAP_RS07045,WP_012824274.1,502586521.0,1514634,1515293,659.0,+,DUF455 domain-containing protein,0.6,15,0.9999999997461622,2407.9999993887586,62.0,0.9999999914267739,2407.9999793556713,57.0,nonessential
1345,HNEAP_RS07050,WP_041600394.1,753844777.0,1515438,1518029,2591.0,+,hypothetical protein,0.5779,47,0.9999999994109993,2407.999998581686,168.0,0.9999999996507211,2407.999999158936,165.0,nonessential
1346,HNEAP_RS12260,WP_012824276.1,502586523.0,1518467,1519006,539.0,-,DUF2237 domain-containing protein,0.5704,10,0.9999650351793359,2407.915804711841,41.0,0.9999824833702852,2407.9578199556468,41.0,nonessential
1347,HNEAP_RS07065,WP_012824277.1,502586524.0,1518999,1519553,554.0,-,glutathione peroxidase,0.5423,12,0.6401294832745812,1541.4317957251915,23.0,0.6935846651357911,1670.151873646985,23.0,nonessential
1348,HNEAP_RS07070,WP_012824278.1,502586525.0,1519717,1521162,1445.0,-,DNA polymerase III subunit epsilon,0.5906,20,0.9999999999814477,2407.999999955326,112.0,0.9999999999993607,2407.9999999984607,114.0,nonessential
1349,HNEAP_RS07075,WP_012824279.1,502586526.0,1521159,1522502,1343.0,-,DASH family cryptochrome,0.5908,29,0.9999999983913984,2407.9999961264875,100.0,0.9999999944616986,2407.9999866637704,96.0,nonessential
1350,HNEAP_RS07080,WP_012824280.1,502586527.0,1522511,1523053,542.0,-,NADH:ubiquinone oxidoreductase complex I intermediate-associated protein 30,0.5764,13,0.9888443302604317,2381.1371472671194,32.0,0.979775728645898,2359.2999545793223,30.0,nonessential
1351,HNEAP_RS07085,WP_012824281.1,502586528.0,1523058,1523876,818.0,-,MipA/OmpV family protein,0.5726,26,0.999994039316438,2407.985646673983,59.0,0.9999994404695584,2407.9986526506964,61.0,nonessential
1352,HNEAP_RS07090,WP_012824282.1,502586529.0,1524364,1525527,1163.0,+,efflux RND transporter periplasmic adaptor subunit,0.5662,17,0.999999999999983,2407.999999999959,104.0,0.9999999999999624,2407.9999999999095,101.0,nonessential
1353,HNEAP_RS07095,WP_012824283.1,502586530.0,1525575,1528736,3161.0,+,multidrug efflux RND transporter permease subunit,0.5746,49,0.9998282543023779,2407.586436360126,166.0,0.9999434205530345,2407.8637566917073,165.0,nonessential
1354,HNEAP_RS07100,WP_012824284.1,502586531.0,1528808,1529176,368.0,+,hypothetical protein,0.5664,7,0.7852817270464234,1890.9583987277877,17.0,0.8192741550394953,1972.8121653351047,17.0,nonessential
1355,HNEAP_RS07105,WP_012824285.1,502586532.0,1529177,1529797,620.0,-,DNA-3-methyladenine glycosylase I,0.5089,10,0.7918074305744779,1906.6722928233428,28.0,0.7800635618947105,1878.393057042463,27.0,nonessential
1356,HNEAP_RS07110,WP_012824287.1,502586534.0,1530755,1531375,620.0,+,hypothetical protein,0.6216,3,3.3172460045362847e-10,7.987928378923374e-07,1.0,6.948207930092394e-10,1.6731284695662485e-06,1.0,essential
1357,HNEAP_RS07115,WP_012824288.1,502586535.0,1531368,1532384,1016.0,+,nucleotidyl transferase AbiEii/AbiGii toxin family protein,0.5831,16,0.9995647174680318,2406.9518396630206,62.0,0.9996646576687328,2407.192495666309,61.0,nonessential
1358,HNEAP_RS07120,WP_012824289.1,502586536.0,1532365,1533294,929.0,+,peptidase U49,0.5548,15,0.9795651739112283,2358.792938778238,49.0,0.9734342097625723,2344.029577108274,47.0,nonessential
1359,HNEAP_RS07125,WP_012824290.1,502586537.0,1533322,1533759,437.0,-,hypothetical protein,0.6324,4,0.9984405716947868,2404.2448966410466,30.0,0.9933205515294203,2391.915888082844,27.0,nonessential
1360,HNEAP_RS07130,WP_041600395.1,753844778.0,1533756,1534802,1046.0,-,recombinase,0.6237,13,0.9999872543450471,2407.9693084628734,70.0,0.9998493866513763,2407.637323056514,64.0,nonessential
1361,HNEAP_RS07135,WP_012824291.1,502586538.0,1535393,1535587,194.0,-,hypothetical protein,0.5077,3,0.49357709682422035,1188.5336491527225,7.0,0.5279740301053278,1271.3614644936295,7.0,nonessential
1362,HNEAP_RS07140,WP_081441186.1,1174220005.0,1535887,1536321,434.0,-,group 1 truncated hemoglobin,0.5218,8,0.9910115535634473,2386.355820980781,27.0,0.9938923415711243,2393.292758503267,27.0,nonessential
1363,HNEAP_RS07145,WP_081441187.1,1174220006.0,1536351,1537253,902.0,-,DUF3034 domain-containing protein,0.5626,20,0.6848020565130248,1649.0033520833638,38.0,0.6918262509395277,1665.9176122623826,37.0,nonessential
1364,HNEAP_RS07150,WP_012824294.1,502586542.0,1537515,1538450,935.0,-,response regulator receiver protein,0.563,13,0.9970516119705886,2400.9002816251773,54.0,0.9960501599429467,2398.4887851426156,52.0,nonessential
1365,HNEAP_RS07155,WP_012824295.1,502586543.0,1538513,1539886,1373.0,-,histidine kinase,0.5502,24,0.9941204354327844,2393.8420085221446,73.0,0.9939081497900225,2393.3308246943743,71.0,nonessential
1366,HNEAP_RS07160,WP_012824296.1,502586544.0,1540172,1542694,2522.0,-,DNA internalization-related competence protein ComEC/Rec2,0.5731,54,0.9999681321906789,2407.9232623151547,141.0,0.9999829137796146,2407.9588563813118,139.0,nonessential
1367,HNEAP_RS07165,WP_012824297.1,502586545.0,1542752,1543555,803.0,-,chemotaxis protein CheR,0.5149,16,0.9961603555041468,2398.7541360539853,47.0,0.9987037873956255,2404.8787200486663,48.0,nonessential
1368,HNEAP_RS07170,WP_012824298.1,502586546.0,1543558,1544499,941.0,-,chemotaxis protein CheV,0.5446,17,0.9508975025197026,2289.7611860674438,47.0,0.9549881437930775,2299.6114502537307,46.0,nonessential
1369,HNEAP_RS07175,WP_012824299.1,502586547.0,1544893,1546104,1211.0,+,serine/threonine phosphatase,0.5355,24,0.9999824682605898,2407.9577835715004,78.0,0.9999671259352398,2407.9208392520577,75.0,nonessential
1370,HNEAP_RS07180,WP_012824300.1,502586548.0,1546176,1546736,560.0,+,hypothetical protein,0.5526,11,0.9999998626624946,2407.999669291287,49.0,0.9999999915812131,2407.9999797275614,51.0,nonessential
1371,HNEAP_RS07185,WP_012824301.1,502586549.0,1546763,1547146,383.0,+,DUF1987 domain-containing protein,0.5052,11,0.5471321536400864,1317.494225965328,15.0,0.5948567635663824,1432.4150866678488,15.0,nonessential
1372,HNEAP_RS07190,WP_012824302.1,502586550.0,1547143,1547886,743.0,+,GGDEF domain-containing protein,0.5323,17,0.9999999953186555,2407.9999887273225,64.0,0.9999999964661196,2407.999991490416,63.0,nonessential
1373,HNEAP_RS07195,WP_012824304.1,502586552.0,1548233,1549225,992.0,+,phospholipase A(2),0.5086,27,0.38920437466189944,937.2041341858538,37.0,0.5306722643011681,1277.8588124372127,38.0,nonessential
1374,HNEAP_RS07200,WP_012824305.1,502586553.0,1549590,1551134,1544.0,+,RND transporter,0.5456,35,0.9999999999999986,2407.9999999999964,130.0,0.9999999999999999,2407.9999999999995,131.0,nonessential
1375,HNEAP_RS07205,WP_012824306.1,502586554.0,1551131,1552273,1142.0,+,MexH family multidrug efflux RND transporter periplasmic adaptor subunit,0.5442,20,0.9865837528678203,2375.693676905711,60.0,0.9891071494728235,2381.770015930559,59.0,nonessential
1376,HNEAP_RS07215,WP_012824307.1,502586555.0,1555719,1557104,1385.0,-,class II fumarate hydratase,0.5325,30,4.3728879087891505e-25,1.0529914084364275e-21,0.0,2.4417319688857315e-24,5.879690581076842e-21,0.0,essential
1377,HNEAP_RS07220,WP_012824308.1,502586556.0,1557127,1557894,767.0,-,acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase,0.5378,17,3.236578554192792e-14,7.793681158496244e-11,0.0,8.38935897972748e-14,2.020157642318377e-10,0.0,essential
1378,HNEAP_RS07225,WP_081441188.1,1174220007.0,1557891,1558331,440.0,-,3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ,0.4853,9,1.8252700498674225e-08,4.3952502800807536e-05,0.0,3.152236952599648e-08,7.590586581859953e-05,0.0,essential
1379,HNEAP_RS07230,WP_012824310.1,502586558.0,1558349,1559416,1067.0,-,UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase,0.5599,19,1.7128458692388162e-19,4.124532853127069e-16,0.0,6.4439286838041e-19,1.5516980270600273e-15,0.0,essential
1380,HNEAP_RS07235,WP_012824311.1,502586559.0,1559455,1559973,518.0,-,molecular chaperone Skp,0.501,13,7.753030315808853e-10,1.866929700046772e-06,0.0,1.4751241124760017e-09,3.5520988628422122e-06,0.0,essential
1381,HNEAP_RS07240,WP_012824312.1,502586560.0,1560072,1562474,2402.0,-,outer membrane protein assembly factor BamA,0.506,71,5.673894735939801e-43,1.3662738524143042e-39,0.0,1.1201556922518029e-41,2.6973349069423415e-38,0.0,essential
1382,HNEAP_RS07245,WP_041600397.1,753844780.0,1562471,1562749,278.0,-,hypothetical protein,0.5448,6,0.2236322162387632,538.5063767029418,8.0,0.2544572842381655,612.7331404455025,8.0,nonessential
1383,HNEAP_RS07250,WP_012824313.1,502586561.0,1562895,1564304,1409.0,-,RIP metalloprotease RseP,0.5582,23,0.9983038159847986,2403.915588891395,78.0,0.9988643099072246,2405.265258256597,77.0,nonessential
1384,HNEAP_RS07255,WP_012824314.1,502586562.0,1564359,1565564,1205.0,-,1-deoxy-D-xylulose-5-phosphate reductoisomerase,0.5705,13,6.406031437257431e-22,1.5425723700915894e-18,0.0,2.8605188964596915e-21,6.888129502674937e-18,0.0,essential
1385,HNEAP_RS07260,WP_012824315.1,502586563.0,1565583,1566437,854.0,-,phosphatidate cytidylyltransferase,0.5754,17,3.018654161059297e-09,7.268919219830787e-06,6.0,7.249001667778057e-09,1.745559601600956e-05,6.0,essential
1386,HNEAP_RS07265,WP_012824316.1,502586564.0,1566434,1567201,767.0,-,di-trans poly-cis-decaprenylcistransferase,0.5508,18,1.7298354977633648e-11,4.1654438786141824e-08,2.0,2.6600994804336683e-12,6.4055195488842734e-09,1.0,essential
1387,HNEAP_RS07270,WP_012824317.1,502586565.0,1567208,1567765,557.0,-,ribosome-recycling factor,0.4946,8,1.5978781547521057e-10,3.8476905966430703e-07,0.0,3.1910485750876314e-10,7.684044968811017e-07,0.0,essential
1388,HNEAP_RS07275,WP_012824318.1,502586566.0,1567762,1568502,740.0,-,UMP kinase,0.5358,14,9.659602610635456e-14,2.326032308641018e-10,0.0,2.4212565186552474e-13,5.830385696921836e-10,0.0,essential
1389,HNEAP_RS07280,WP_012824319.1,502586567.0,1568742,1569620,878.0,-,elongation factor Ts,0.5631,20,1.3423182256911713e-09,3.2323022874643404e-06,6.0,3.3203352771651278e-09,7.995367347413627e-06,6.0,essential
1390,HNEAP_RS07285,WP_012824320.1,502586568.0,1569743,1570477,734.0,-,30S ribosomal protein S2,0.5279,22,6.311497897058624e-10,1.5198086936117165e-06,3.0,1.4322532469545434e-09,3.4488658186665404e-06,3.0,essential
1391,HNEAP_RS07290,WP_012824321.1,502586569.0,1570794,1571594,800.0,-,segregation/condensation protein A,0.5805,10,0.997797112998347,2402.6954481000193,48.0,0.9987995015628911,2405.1091997634417,48.0,nonessential
1392,HNEAP_RS07295,WP_012824322.1,502586570.0,1571613,1572269,656.0,-,site-2 protease family protein,0.5677,11,0.9775677526775253,2353.9831484474807,36.0,0.9906846422576251,2385.5686185563613,37.0,nonessential
1393,HNEAP_RS07300,WP_012824323.1,502586571.0,1572272,1572898,626.0,-,threonylcarbamoyl-AMP synthase,0.5407,16,0.9997610708049188,2407.4246584982448,43.0,0.9997598233966012,2407.4216547390156,42.0,nonessential
1394,HNEAP_RS07305,WP_012824324.1,502586572.0,1573046,1573621,575.0,+,septation protein A,0.4896,18,7.708352868593883e-11,1.856171370757407e-07,0.0,1.574195737221829e-10,3.7906633352301643e-07,0.0,essential
1395,HNEAP_RS07310,WP_012824325.1,502586573.0,1573664,1573993,329.0,+,hypothetical protein,0.5364,9,0.5666052623952651,1364.3854718477983,13.0,0.6105668166557803,1470.244894507119,13.0,nonessential
1396,HNEAP_RS07315,WP_081441121.1,1174219940.0,1573911,1575002,1091.0,+,hypothetical protein,0.5018,20,0.7469887490466856,1798.7489077044188,47.0,0.6605721736958903,1590.6577942597037,44.0,nonessential
1397,HNEAP_RS07320,WP_081441122.1,1174219941.0,1575176,1575778,602.0,+,hypothetical protein,0.5257,17,0.317393918422695,764.2845555618495,21.0,0.2932162545072778,706.0647408535249,20.0,nonessential
1398,HNEAP_RS07325,WP_012824328.1,502586576.0,1575868,1577085,1217.0,-,diguanylate phosphodiesterase,0.5066,30,3.070318840267837e-05,0.0739332776736495,23.0,0.00014216713840306834,0.34233846927458855,24.0,nonessential
1399,HNEAP_RS07330,WP_012824329.1,502586577.0,1577267,1579363,2096.0,-,polyribonucleotide nucleotidyltransferase,0.5646,35,0.19605570429470454,472.1021359416485,75.0,0.17687381001516722,425.91213451652266,72.0,nonessential
1400,HNEAP_RS07335,WP_012824330.1,502586579.0,1579649,1579918,269.0,-,30S ribosomal protein S15,0.5222,6,0.0013685022169508854,3.295353338417732,2.0,0.0018039233427072255,4.343847409238999,2.0,nonessential
1401,HNEAP_RS07340,WP_012824331.1,502586580.0,1580030,1580986,956.0,-,tRNA pseudouridine(55) synthase TruB,0.5486,21,8.980820233975153e-05,0.21625815123412168,17.0,3.089416642315416e-05,0.07439315274695522,15.0,nonessential
1402,HNEAP_RS07345,WP_012824332.1,502586581.0,1580983,1581402,419.0,-,30S ribosome-binding factor RbfA,0.531,9,0.05480144862738484,131.9618882947427,10.0,0.037862516753043314,91.1729403413283,9.0,nonessential
1403,HNEAP_RS07350,WP_012824333.1,502586582.0,1581468,1584161,2693.0,-,translation initiation factor IF-2,0.5572,55,2.7252020075102823e-44,6.56228643408476e-41,2.0,7.250876253393979e-43,1.7460110018172702e-39,2.0,essential
1404,HNEAP_RS07355,WP_012824334.1,502586583.0,1584295,1585770,1475.0,-,transcription termination/antitermination protein NusA,0.5596,18,8.660736651041723e-20,2.085505385570847e-16,5.0,1.2859154608356928e-22,3.0964844296923483e-19,2.0,essential
1405,HNEAP_RS07360,WP_012824335.1,502586584.0,1585792,1586292,500.0,-,ribosome assembly cofactor RimP,0.5669,7,0.0002329024108617774,0.56082900535516,6.0,0.0003622461576344646,0.8722887475837908,6.0,nonessential
1406,HNEAP_RS07365,WP_012824336.1,502586585.0,1586512,1587018,506.0,-,hypothetical protein,0.497,14,0.9794112673293293,2358.422331729025,29.0,0.9857502125736445,2373.6865118773358,29.0,nonessential
1407,HNEAP_RS07370,WP_012824337.1,502586586.0,1587070,1588215,1145.0,-,molecular chaperone DnaJ,0.575,14,0.020847244995283645,50.20016594864302,32.0,0.022338514183595008,53.791142154096775,31.0,nonessential
1408,HNEAP_RS07375,WP_012824338.1,502586587.0,1588336,1590240,1904.0,-,molecular chaperone DnaK,0.547,30,5.459350742383754e-28,1.314611658766008e-24,4.0,5.1228554082756774e-27,1.2335835823127831e-23,4.0,essential
1409,HNEAP_RS07380,WP_012824339.1,502586588.0,1590372,1590944,572.0,-,nucleotide exchange factor GrpE,0.5201,8,2.1707543351960427e-07,0.0005227176439152071,3.0,2.4115731230769567e-06,0.005807068080369311,4.0,essential
1410,HNEAP_RS07385,WP_049772498.1,908628465.0,1591142,1592059,917.0,+,hypothetical protein,0.5763,13,7.295896169298302e-13,1.756851797567031e-09,3.0,2.0766603095988574e-12,5.000598025514049e-09,3.0,essential
1411,HNEAP_RS07390,WP_012824341.1,502586590.0,1592068,1593732,1664.0,+,DNA repair protein RecN,0.5892,24,0.7166840817742621,1725.7752689124231,70.0,0.7188830127557916,1731.0702947159461,68.0,nonessential
1412,HNEAP_RS07395,WP_012824342.1,502586591.0,1593788,1594741,953.0,-,cytochrome c,0.5545,27,0.9972158846565777,2401.295850253039,55.0,0.99631576641504,2399.1283655274165,53.0,nonessential
1413,HNEAP_RS07400,WP_012824343.1,502586592.0,1594738,1595418,680.0,-,cytochrome c,0.5932,15,0.9999999284583178,2407.999827727629,57.0,0.9999999392766945,2407.9998537782803,56.0,nonessential
1414,HNEAP_RS07405,WP_012824344.1,502586593.0,1595731,1598643,2912.0,-,peptidase M16,0.5633,56,5.4865093594615166e-45,1.321151453758333e-41,4.0,1.5633797649168247e-46,3.764618473919714e-43,2.0,essential
1415,HNEAP_RS07410,WP_012824345.1,502586594.0,1598935,1599555,620.0,+,flavin reductase family protein,0.5137,13,0.999632500535521,2407.1150612895344,42.0,0.9998040998004766,2407.528272319548,42.0,nonessential
1416,HNEAP_RS07415,WP_012824346.1,502586595.0,1599946,1601274,1328.0,+,23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD,0.5696,26,0.9981926550846113,2403.647913443744,74.0,0.9958453110871396,2397.995509097832,70.0,nonessential
1417,HNEAP_RS07425,WP_012824347.1,502586596.0,1601806,1602702,896.0,-,lipid A biosynthesis acyltransferase,0.524,25,0.9997497757197344,2407.3974599331204,57.0,0.9998840784531007,2407.7208609150666,57.0,nonessential
1418,HNEAP_RS07430,WP_012824348.1,502586597.0,1602710,1604164,1454.0,-,cytochrome P450,0.532,39,0.24542328443092754,590.9792689096735,52.0,0.3238829416638477,779.9101235265452,52.0,nonessential
1419,HNEAP_RS07435,WP_012824349.1,502586598.0,1604157,1605425,1268.0,-,capsule polysaccharide biosynthesis protein,0.5225,35,0.2474209073060851,595.7895447930529,45.0,0.26902013934659164,647.8004955465926,44.0,nonessential
1420,HNEAP_RS07440,WP_081441123.1,1174219942.0,1605537,1606574,1037.0,-,NAD(P)-dependent oxidoreductase,0.5434,27,0.9981634135824284,2403.577499906488,60.0,0.9964367794231663,2399.4197648509844,57.0,nonessential
1421,HNEAP_RS07445,WP_081441124.1,1174219943.0,1606592,1607842,1250.0,-,hypothetical protein,0.4932,40,0.9815172829605834,2363.493617369085,64.0,0.9796040831176006,2358.8866321471824,62.0,nonessential
1422,HNEAP_RS07450,WP_012824352.1,502586601.0,1607943,1609169,1226.0,-,polysaccharide export protein,0.5175,29,0.9957303510400323,2397.7186853043977,67.0,0.9952421317436613,2396.5430532387363,65.0,nonessential
1423,HNEAP_RS07455,WP_012824353.1,502586602.0,1609350,1609904,554.0,+,dTDP-4-dehydrorhamnose 3 5-epimerase,0.5207,12,0.9761192179084702,2350.4950767235964,31.0,0.8717966699381294,2099.286381211016,26.0,nonessential
1424,HNEAP_RS07460,WP_012824354.1,502586603.0,1609951,1610871,920.0,+,dTDP-4-dehydrorhamnose reductase,0.5451,19,0.9500146023113939,2287.6351623658365,46.0,0.936275484166998,2254.551365874131,44.0,nonessential
1425,HNEAP_RS07465,WP_012824355.1,502586604.0,1610888,1611955,1067.0,+,dTDP-glucose 4 6-dehydratase,0.5262,35,0.004177394905683358,10.059166932885526,26.0,6.73490801180335e-07,0.0016217658492422467,14.0,ambiguous
1426,HNEAP_RS07470,WP_012824356.1,502586605.0,1611984,1612355,371.0,+,four helix bundle protein,0.4086,15,0.19833195082275218,477.58333758118727,11.0,0.050725100828833775,122.14604279583173,8.0,nonessential
1427,HNEAP_RS07475,WP_012824357.1,502586606.0,1612442,1613314,872.0,+,glucose-1-phosphate thymidylyltransferase,0.4926,24,0.698962345490362,1683.1013279407916,37.0,0.7039863677907167,1695.1991736400457,36.0,nonessential
1428,HNEAP_RS07480,WP_012824358.1,502586607.0,1613337,1616213,2876.0,+,glycosyltransferase family 2 protein,0.5002,92,0.11215259594008088,270.0634510237148,101.0,0.1611252596963906,387.9896253489086,100.0,nonessential
1429,HNEAP_RS07485,WP_012824359.1,502586608.0,1616218,1618110,1892.0,+,capsular polysaccharide biosynthesis protein,0.3545,113,0.9979283317477191,2403.0114228485077,100.0,0.9966927892364025,2400.036236481257,96.0,nonessential
1430,HNEAP_RS07490,WP_012824360.1,502586609.0,1618134,1618499,365.0,+,sulfate adenylyltransferase,0.5383,10,0.1404662882886772,338.24282219913465,10.0,0.057052494582606535,137.38240695491655,8.0,nonessential
1431,HNEAP_RS07500,WP_012824361.1,502586610.0,1618831,1619067,236.0,+,DUF2442 domain-containing protein,0.4219,9,0.9933490438518965,2391.9844975953665,17.0,0.9950877803263097,2396.171375025754,17.0,nonessential
1432,HNEAP_RS07505,WP_012824362.1,502586611.0,1619366,1620268,902.0,+,sulfate adenylyltransferase subunit CysD,0.546,26,0.10347234165792552,249.16139871228464,28.0,0.07280775230129595,175.32106754152065,26.0,nonessential
1433,HNEAP_RS07510,WP_012824363.1,502586612.0,1620268,1621728,1460.0,+,sulfate adenylyltransferase subunit CysN,0.5332,44,0.733517009580217,1766.3089590691627,62.0,0.6790784438868229,1635.2208928794696,59.0,nonessential
1434,HNEAP_RS07515,WP_012824364.1,502586613.0,1621738,1623477,1739.0,+,carboxylate transporter,0.5259,47,0.6262183500250187,1507.933786860245,71.0,0.5841185090506358,1406.557369793931,68.0,nonessential
1435,HNEAP_RS07520,WP_012824365.1,502586614.0,1623716,1624312,596.0,+,adenylyl-sulfate kinase,0.5059,18,3.293182785868707e-11,7.929984148371847e-08,0.0,6.903006277537521e-11,1.662243911631035e-07,0.0,essential
1436,HNEAP_RS07525,WP_012824366.1,502586615.0,1624673,1625476,803.0,+,3'(2') 5'-bisphosphate nucleotidase,0.4988,21,0.6254711805607807,1506.1346027903598,33.0,0.7499303355002754,1805.8322478846633,34.0,nonessential
1437,HNEAP_RS07530,WP_012824367.1,502586616.0,1625476,1626510,1034.0,+,hypothetical protein,0.5043,47,0.29228659503085364,703.8261208342956,37.0,0.2473363210297536,595.5858610396466,35.0,nonessential
1438,HNEAP_RS07535,WP_012824368.1,502586617.0,1626879,1629080,2201.0,-,glycosyltransferase family 2 protein,0.505,82,0.09562692099249401,230.26962574992558,75.0,0.06847605431470188,164.89033878980214,71.0,nonessential
1439,HNEAP_RS07540,WP_081441125.1,1174219944.0,1629084,1631243,2159.0,-,hypothetical protein,0.4907,63,0.04381149671102751,105.49808408015426,70.0,0.06083861473601212,146.4993842843172,69.0,nonessential
1440,HNEAP_RS07545,WP_012824370.1,502586619.0,1631266,1631940,674.0,-,ABC transporter ATP-binding protein,0.4696,22,0.027973577299235275,67.36037413655855,17.0,0.039145551043010214,94.2624869115686,17.0,nonessential
1441,HNEAP_RS07550,WP_012824371.1,502586620.0,1631937,1632725,788.0,-,sugar ABC transporter permease,0.5272,25,0.07321081314575094,176.29163805496827,23.0,0.09920247809334444,238.8795672487734,23.0,nonessential
1442,HNEAP_RS07555,WP_041600400.1,753844783.0,1632871,1634001,1130.0,-,hypothetical protein,0.4819,36,0.09871951857243044,237.7166007224125,36.0,0.10532843995638254,253.63088341496916,35.0,nonessential
1443,HNEAP_RS07560,WP_012824373.1,502586622.0,1633998,1635335,1337.0,-,8-amino-7-oxononanoate synthase,0.5441,39,0.9999869971214923,2407.9686890685534,85.0,0.9999633372163815,2407.9117160170467,81.0,nonessential
1444,HNEAP_RS07565,WP_012824374.1,502586623.0,1635332,1642855,7523.0,-,type I polyketide synthase,0.5738,150,0.9999998667253942,2407.999679074749,389.0,0.9999999941985809,2407.9999860301828,389.0,nonessential
1445,HNEAP_RS07570,WP_012824375.1,502586625.0,1643288,1643671,383.0,-,lactoylglutathione lyase,0.5208,13,0.34013108415932525,819.0356506556552,13.0,0.2846892030172099,685.5316008654414,12.0,nonessential
1446,HNEAP_RS07575,WP_012824376.1,502586626.0,1643884,1645074,1190.0,-,O-succinylhomoserine sulfhydrylase,0.5877,15,1.1760003716350139e-21,2.8318088948971134e-18,0.0,5.1543478425493224e-21,1.2411669604858769e-17,0.0,essential
1447,HNEAP_RS07580,WP_012824377.1,502586627.0,1645084,1645443,359.0,-,hypothetical protein,0.5556,8,0.9999999999999999,2407.9999999999995,65.0,0.9999999999999999,2407.9999999999995,65.0,nonessential
1448,HNEAP_RS07585,WP_012824378.1,502586628.0,1645475,1646332,857.0,-,bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase,0.5711,16,9.501739477705927e-06,0.02288018866231587,12.0,1.909769218309788e-05,0.045987242776899695,12.0,essential
1449,HNEAP_RS07590,WP_012824379.1,502586629.0,1646434,1647852,1418.0,+,ribonuclease BN,0.5553,25,0.999999999096584,2407.999997824574,105.0,0.9999999992789139,2407.9999982636245,103.0,nonessential
1450,HNEAP_RS07595,WP_012824380.1,502586630.0,1647839,1649185,1346.0,+,hypothetical protein,0.5501,22,0.9626043436056392,2317.951259402379,66.0,0.9475844505281821,2281.7833568718625,63.0,nonessential
1451,HNEAP_RS07600,WP_012824381.1,502586631.0,1649208,1650509,1301.0,-,replication-associated recombination protein A,0.5929,28,0.9999596246122119,2407.902776066206,81.0,0.9999754563934593,2407.94089899545,80.0,nonessential
1452,HNEAP_RS07605,WP_012824382.1,502586632.0,1650590,1651006,416.0,-,GNAT family N-acetyltransferase,0.4796,15,0.006520301793376847,15.700886718451448,7.0,0.008907332094689819,21.448855684013083,7.0,nonessential
1453,HNEAP_RS12265,WP_012824383.1,502586633.0,1651025,1651846,821.0,-,outer membrane lipoprotein carrier protein LolA,0.5341,16,2.686887027057797e-06,0.0064700239611551755,10.0,1.6204250520576963e-06,0.0039019835253549327,9.0,essential
1454,HNEAP_RS07615,WP_012824384.1,502586634.0,1651806,1654166,2360.0,-,DNA translocase FtsK,0.5735,29,6.529760754179315e-23,1.5723663896063791e-19,17.0,5.014733490143559e-25,1.207547824426569e-21,13.0,essential
1455,HNEAP_RS07620,WP_012824386.1,502586636.0,1654664,1655191,527.0,-,ClpXP protease specificity-enhancing factor,0.5663,6,0.9996276051197305,2407.103273128311,37.0,0.9984936470846131,2404.372702179748,34.0,nonessential
1456,HNEAP_RS07625,WP_012824387.1,502586637.0,1655201,1655830,629.0,-,stringent starvation protein A,0.5603,11,2.8370536092314115e-08,6.83162509102924e-05,3.0,5.6542524971955834e-08,0.00013615440013246965,3.0,essential
1457,HNEAP_RS07630,WP_049772502.1,908628469.0,1655995,1656933,938.0,-,ChbG/HpnK family deacetylase,0.5506,15,0.9999999985085979,2407.9999964087037,77.0,0.999999995509493,2407.9999891868592,74.0,nonessential
1458,HNEAP_RS07635,WP_012824389.1,502586639.0,1656926,1658548,1622.0,+,glycosyl transferase family 39,0.5539,32,0.9999999999997633,2407.99999999943,128.0,0.9999999999999377,2407.99999999985,127.0,nonessential
1459,HNEAP_RS07640,WP_012824390.1,502586640.0,1658500,1658946,446.0,-,GtrA family protein,0.5839,11,0.9448165997537269,2275.1183722069745,24.0,0.9349927331149654,2251.4625013408368,23.0,nonessential
1460,HNEAP_RS07645,WP_012824391.1,502586641.0,1658939,1659943,1004.0,-,glycosyltransferase,0.5711,17,0.551734183986022,1328.575915038341,40.0,0.5652436532244722,1361.1067169645291,39.0,nonessential
1461,HNEAP_RS07650,WP_012824392.1,502586642.0,1660300,1661484,1184.0,+,cyclopropane-fatty-acyl-phospholipid synthase,0.5519,27,0.9980928360641055,2403.407549242366,67.0,0.9985862733583247,2404.595746246846,66.0,nonessential
1462,HNEAP_RS07655,WP_012824393.1,502586643.0,1661547,1661858,311.0,-,RnfH family protein,0.5609,4,0.00032606130427893635,0.7851556207036787,2.0,6.708935838524526e-05,0.1615511749916706,1.0,nonessential
1463,HNEAP_RS07660,WP_041600401.1,753844784.0,1661855,1662313,458.0,-,ubiquinone-binding protein,0.5338,9,1.7547770642389374e-07,0.0004225503170687361,1.0,3.006957013574418e-07,0.0007240752488687199,1.0,essential
1464,HNEAP_RS07665,WP_012824395.1,502586645.0,1662717,1663193,476.0,+,SsrA-binding protein SmpB,0.5325,8,3.244022730900834e-05,0.07811606736009209,4.0,5.196926870162084e-05,0.12514199903350298,4.0,nonessential
1465,HNEAP_RS07670,WP_049772503.1,908628470.0,1663258,1663467,209.0,+,hypothetical protein,0.5667,3,0.2734416518587907,658.4474976759681,6.0,0.18174147172690586,437.6334639183893,5.0,nonessential
1466,HNEAP_RS12550,WP_012824396.1,502586646.0,1663570,1664490,920.0,+,ArsR family transcriptional regulator,0.5429,14,0.9999710756899247,2407.930350261339,62.0,0.999999171056346,2407.998003903681,66.0,nonessential
1467,HNEAP_RS07680,WP_012824397.1,502586647.0,1664494,1665504,1010.0,+,type I glyceraldehyde-3-phosphate dehydrogenase,0.5945,12,0.9999754773790216,2407.940949528684,67.0,0.9999437751878235,2407.864610652279,64.0,nonessential
1468,HNEAP_RS07685,WP_012824398.1,502586648.0,1665533,1666735,1202.0,+,MFS transporter,0.5777,22,0.9999999928203823,2407.9999827114807,90.0,0.9999999423570278,2407.999861195723,85.0,nonessential
1469,HNEAP_RS07690,WP_081441126.1,1174219945.0,1667015,1668502,1487.0,+,hypothetical protein,0.3434,97,7.655773607206646e-07,0.0018435102846153604,26.0,2.172519025724533e-06,0.005231425813944676,26.0,essential
1470,HNEAP_RS07695,WP_041600402.1,753844785.0,1668495,1668926,431.0,+,DUF2492 domain-containing protein,0.3218,30,0.010660758743740702,25.67110705492761,8.0,0.014416441900691414,34.714792096864926,8.0,nonessential
1471,HNEAP_RS07700,WP_012824401.1,502586651.0,1669033,1671099,2066.0,-,ATP-dependent DNA helicase Rep,0.5931,30,0.0012626768298727934,3.0405258063336866,56.0,0.002935577507243967,7.068870637443472,56.0,nonessential
1472,HNEAP_RS07705,WP_012824402.1,502586652.0,1671096,1672031,935.0,-,EamA/RhaT family transporter,0.5919,15,0.9168180888569146,2207.6979579674503,45.0,0.8647110351370482,2082.224172610012,42.0,nonessential
1473,HNEAP_RS07710,WP_012824403.1,502586653.0,1672059,1675982,3923.0,-,phosphoribosylformylglycinamidine synthase,0.5961,49,1.0062275089882339e-69,2.422995841643667e-66,0.0,1.3133112430151097e-67,3.162453473180384e-64,0.0,essential
1474,HNEAP_RS07715,WP_081441127.1,1174219946.0,1676186,1676995,809.0,+,flagella basal body P-ring formation protein FlgA,0.5358,13,0.9999997609068267,2407.999424263639,63.0,0.9999999622955684,2407.9999092077287,64.0,nonessential
1475,HNEAP_RS12270,WP_012824405.1,502586655.0,1677165,1677479,314.0,+,flagellar biosynthesis anti-sigma factor FlgM,0.5016,7,0.9999998334256515,2407.9995988889686,33.0,0.9999999176864338,2407.9998017889325,33.0,nonessential
1476,HNEAP_RS07725,WP_012824406.1,502586656.0,1677476,1678030,554.0,+,flagellar protein FlgN,0.5982,5,0.9438791435697833,2272.860977716038,29.0,0.9591743885980849,2309.6919277441884,29.0,nonessential
1477,HNEAP_RS07730,WP_081441189.1,1174220008.0,1678055,1678618,563.0,-,16S rRNA (guanine(966)-N(2))-methyltransferase RsmD,0.5869,9,0.44041501598886207,1060.5193585011798,21.0,0.4984135448261877,1200.17981594146,21.0,nonessential
1478,HNEAP_RS07735,WP_012824408.1,502586658.0,1678970,1680145,1175.0,+,signal recognition particle-docking protein FtsY,0.5765,13,2.1588668236036243e-21,5.198551311237527e-18,0.0,9.28758125488133e-21,2.2364495661754243e-17,0.0,essential
1479,HNEAP_RS07740,WP_012824409.1,502586659.0,1680142,1680810,668.0,+,cell division ATP-binding protein FtsE,0.5859,8,1.7835592795216288e-12,4.294810745088082e-09,0.0,4.088269676502006e-12,9.84455338101683e-09,0.0,essential
1480,HNEAP_RS07745,WP_012824410.1,502586660.0,1680812,1681795,983.0,+,ABC transporter permease,0.5833,17,3.6956158351452356e-11,8.899042931029727e-08,6.0,3.0166636372570462e-09,7.2641260385149675e-06,8.0,essential
1481,HNEAP_RS07750,WP_012824411.1,502586661.0,1681833,1683056,1223.0,-,methyl-accepting chemotaxis protein,0.5531,12,0.9999999999519842,2407.9999998843778,98.0,0.999999999791669,2407.999999498339,94.0,nonessential
1482,HNEAP_RS07755,WP_012824412.1,502586662.0,1683171,1684052,881.0,+,phytoene synthase,0.5771,13,0.9964982026586084,2399.567672001929,51.0,0.9924405623577962,2389.7968741575733,48.0,nonessential
1483,HNEAP_RS07760,WP_012824413.1,502586663.0,1684105,1684860,755.0,+,short-chain dehydrogenase/reductase SDR,0.5952,5,0.9993288975189919,2406.3839852257324,48.0,0.9969461686808825,2400.646374183565,44.0,nonessential
1484,HNEAP_RS07765,WP_012824414.1,502586664.0,1684903,1685085,182.0,+,hypothetical protein,0.5082,6,0.9999866601402074,2407.9678776176197,20.0,0.9999915271634584,2407.979597409608,20.0,nonessential
1485,HNEAP_RS07770,WP_012824415.1,502586665.0,1685137,1686609,1472.0,+,DUF853 domain-containing protein,0.5818,19,0.5651422348123484,1360.862501428135,59.0,0.49940945148182647,1202.577959168238,56.0,nonessential
1486,HNEAP_RS07775,WP_012824416.1,502586667.0,1686876,1689545,2669.0,+,pyruvate dehydrogenase (acetyl-transferring)  homodimeric type,0.5772,43,1.9108311211241742e-27,4.6012813396670114e-24,17.0,1.5968342407686616e-30,3.845176851770937e-27,12.0,essential
1487,HNEAP_RS07780,WP_012824417.1,502586668.0,1689625,1690953,1328.0,+,dihydrolipoyllysine-residue acetyltransferase,0.5854,15,1.0267761375323588e-14,2.4724769391779198e-11,8.0,6.165521405323602e-15,1.4846575544019234e-11,7.0,essential
1488,HNEAP_RS07785,WP_012824418.1,502586669.0,1690979,1692748,1769.0,+,dihydrolipoyl dehydrogenase,0.5944,19,1.722659625621188e-21,4.1481643784958204e-18,8.0,1.1007863087996893e-23,2.650693431589652e-20,5.0,essential
1489,HNEAP_RS07790,WP_012824419.1,502586670.0,1692793,1693362,569.0,-,protein kinase,0.507,14,0.33710156053791795,811.7405577753065,20.0,0.3916575892902231,943.1114750108572,20.0,nonessential
1490,HNEAP_RS07795,WP_012824420.1,502586671.0,1693670,1694461,791.0,+,sulfite exporter TauE/SafE family protein,0.5177,16,1.2245505641921075e-14,2.9487177585745945e-11,0.0,3.27011129713467e-14,7.874428003500285e-11,0.0,essential
1491,HNEAP_RS07800,WP_012824421.1,502586672.0,1694481,1695005,524.0,+,pantetheine-phosphate adenylyltransferase,0.5371,8,6.080567652369116e-10,1.4642006906904831e-06,0.0,1.1655663505176072e-09,2.806683772046398e-06,0.0,essential
1492,HNEAP_RS07805,WP_012824422.1,502586673.0,1695037,1695282,245.0,+,ferredoxin,0.5244,5,4.9086971853635244e-05,0.11820142822355367,0.0,6.654180697503336e-05,0.16023267119588033,0.0,ambiguous
1493,HNEAP_RS07810,WP_012824423.1,502586674.0,1695381,1695650,269.0,-,acyl carrier protein,0.5259,2,0.04245411170363525,102.22950098235368,5.0,0.05153004561354828,124.08434983742426,5.0,nonessential
1494,HNEAP_RS07815,WP_012824424.1,502586675.0,1695647,1696942,1295.0,-,serine--tRNA ligase,0.5849,19,9.125175302654802e-22,2.197342212879276e-18,1.0,4.416662951969155e-21,1.0635324388341725e-17,1.0,essential
1495,HNEAP_RS07820,WP_012824425.1,502586676.0,1696974,1697450,476.0,-,transcription elongation factor GreA,0.5346,9,6.264166825376698e-06,0.015084113715507089,3.0,1.033758266958318e-05,0.0248928990683563,3.0,essential
1496,HNEAP_RS07825,WP_012824426.1,502586677.0,1697450,1700683,3233.0,-,carbamoyl-phosphate synthase large subunit,0.5702,50,1.8511402478583184e-55,4.4575457168428306e-52,1.0,9.938060811053747e-54,2.3930850433017424e-50,1.0,essential
1497,HNEAP_RS07830,WP_012824427.1,502586678.0,1700774,1701907,1133.0,-,carbamoyl-phosphate synthase small subunit,0.5653,21,2.4566707801881496e-14,5.915663238693064e-11,5.0,8.589936438318135e-14,2.068456694347007e-10,5.0,essential
1498,HNEAP_RS07835,WP_012824428.1,502586679.0,1702099,1702905,806.0,-,4-hydroxy-tetrahydrodipicolinate reductase,0.5812,15,6.670499091611344e-15,1.6062561812600116e-11,0.0,6.037806084390042e-13,1.453903705121122e-09,1.0,essential
1499,HNEAP_RS07840,WP_012824429.1,502586680.0,1703088,1703915,827.0,+,sulfurtransferase,0.5543,9,0.8001045117790931,1926.6516643640564,37.0,0.8838242712461345,2128.248845160692,38.0,nonessential
1500,HNEAP_RS07845,WP_012824430.1,502586681.0,1703946,1704497,551.0,-,oligoribonuclease,0.5525,6,0.8441514361777254,2032.7166583159626,26.0,0.8773001648016856,2112.538796842459,26.0,nonessential
1501,HNEAP_RS07850,WP_012824431.1,502586682.0,1704687,1706132,1445.0,+,magnesium transporter,0.5692,24,0.9999999996788006,2407.999999226552,108.0,0.9999999998792233,2407.9999997091695,107.0,nonessential
1502,HNEAP_RS07855,WP_012824432.1,502586683.0,1706129,1707094,965.0,+,ribosome small subunit-dependent GTPase A,0.5787,19,0.2706006286710801,651.6063138399609,34.0,0.13133011627134186,316.2429199813912,30.0,nonessential
1503,HNEAP_RS07860,WP_012824433.1,502586684.0,1707116,1707460,344.0,-,histidine triad nucleotide-binding protein,0.5304,10,0.06946810065872823,167.2791863862176,8.0,0.044563048921328896,107.30782180255999,7.0,nonessential
1504,HNEAP_RS07865,WP_012824434.1,502586685.0,1707801,1708223,422.0,+,hypothetical protein,0.4941,8,0.013127594911894271,31.611248547841406,8.0,0.007722269195616953,18.595224223045623,7.0,nonessential
1505,HNEAP_RS07870,WP_012824435.1,502586686.0,1708331,1709950,1619.0,-,lytic transglycosylase,0.5179,51,0.321713626083595,774.6864116092968,60.0,0.31603620840349406,761.0151898356137,58.0,nonessential
1506,HNEAP_RS07875,WP_012824436.1,502586687.0,1709954,1710754,800.0,-,hydroxyacylglutathione hydrolase,0.5556,12,0.0013396317776317127,3.225833320537164,16.0,0.004371952417109506,10.52766142039969,17.0,nonessential
1507,HNEAP_RS07880,WP_012824437.1,502586688.0,1710934,1711608,674.0,-,hypothetical protein,0.5437,13,0.9325044833949666,2245.4707960150795,34.0,0.9517664466673313,2291.853603574934,34.0,nonessential
1508,HNEAP_RS07885,WP_012824438.1,502586689.0,1711725,1712219,494.0,-,ribosomal-protein-alanine N-acetyltransferase,0.5313,16,0.9600947157844283,2311.9080756089033,27.0,0.9302555791033578,2240.0554344808857,25.0,nonessential
1509,HNEAP_RS07890,WP_012824439.1,502586690.0,1712216,1712647,431.0,-,hypothetical protein,0.5648,8,0.9999999999288768,2407.9999998287353,48.0,0.9999999997428736,2407.9999993808397,46.0,nonessential
1510,HNEAP_RS07895,WP_012824440.1,502586691.0,1712672,1714255,1583.0,-,2-isopropylmalate synthase,0.5612,24,2.2947069474380695e-13,5.525654329430871e-10,15.0,1.0268732942736689e-12,2.4727108926109946e-09,15.0,essential
1511,HNEAP_RS12275,WP_081441128.1,1174219947.0,1714521,1715702,1181.0,+,MerR family transcriptional regulator,0.544,31,1.947861599416609e-10,4.6904507313951946e-07,11.0,6.005995500426559e-10,1.4462437165027153e-06,11.0,essential
1512,HNEAP_RS07905,WP_012824442.1,502586693.0,1715762,1716217,455.0,+,signal transduction histidine kinase,0.4627,11,0.050115906492683396,120.67910283438162,11.0,0.03579250707077205,86.1883570264191,10.0,nonessential
1513,HNEAP_RS07910,WP_012824443.1,502586694.0,1716275,1717972,1697.0,+,type IV-A pilus assembly ATPase PilB,0.5224,43,0.8445344985218892,2033.6390724407092,75.0,0.848658704072705,2043.5701594070738,73.0,nonessential
1514,HNEAP_RS07915,WP_012824444.1,502586695.0,1717984,1719222,1238.0,+,type II secretion system F family protein,0.4875,21,0.008498112531401137,20.46345497561394,33.0,0.014571860490541292,35.08904006122343,33.0,nonessential
1515,HNEAP_RS07920,WP_012824445.1,502586696.0,1719256,1720140,884.0,+,prepilin peptidase,0.5424,22,0.12633302508604227,304.2099244071898,28.0,0.09016785436528939,217.12419331161684,26.0,nonessential
1516,HNEAP_RS07925,WP_012824446.1,502586697.0,1720182,1720811,629.0,+,dephospho-CoA kinase,0.5317,15,8.653969717934253e-12,2.083875908078568e-08,0.0,1.8898819733406782e-11,4.550835791804353e-08,0.0,essential
1517,HNEAP_RS07930,WP_012824447.1,502586698.0,1720814,1721188,374.0,-,hypothetical protein,0.568,7,0.2758500223599333,664.2468538427194,12.0,0.3161420620810513,761.2700854911715,12.0,nonessential
1518,HNEAP_RS07935,WP_012824448.1,502586699.0,1721277,1721573,296.0,-,hypothetical protein,0.4646,6,0.6053862094284272,1457.7699923036528,12.0,0.5313552912307301,1279.503541283598,11.0,nonessential
1519,HNEAP_RS07940,WP_012824449.1,502586700.0,1721644,1723305,1661.0,-,sigma-54-dependent Fis family transcriptional regulator,0.4922,56,0.9999999760692578,2407.9999423747727,113.0,0.9999999833867061,2407.9999599951884,111.0,nonessential
1520,HNEAP_RS07945,WP_012824450.1,502586701.0,1724015,1727551,3536.0,+,hybrid sensor histidine kinase/response regulator,0.5454,83,0.9999989206559321,2407.9974009394846,198.0,0.9999977039476929,2407.994471106045,191.0,nonessential
1521,HNEAP_RS07950,WP_012824451.1,502586702.0,1727538,1728416,878.0,+,response regulator,0.5643,21,0.9482155346722303,2283.3030074907306,44.0,0.9512979290868507,2290.7254132411367,43.0,nonessential
1522,HNEAP_RS07955,WP_012824452.1,502586703.0,1728425,1730257,1832.0,-,VWA domain-containing protein,0.5892,29,0.016706862965709397,40.23012602142823,55.0,0.011610068997739609,27.95704614655698,52.0,nonessential
1523,HNEAP_RS07960,WP_012824453.1,502586704.0,1730375,1731388,1013.0,-,hypothetical protein,0.5562,28,0.5287930614393087,1273.3336919458554,40.0,0.5427331863387561,1306.9015127037246,39.0,nonessential
1524,HNEAP_RS07965,WP_012824454.1,502586705.0,1731561,1732556,995.0,-,formamidase,0.5934,16,0.9999999810803717,2407.999954441535,77.0,0.9999999975572034,2407.9999941177457,78.0,nonessential
1525,HNEAP_RS07970,WP_012824455.1,502586706.0,1732677,1734047,1370.0,-,allantoin permease,0.5573,21,0.9499003237057633,2287.359979483478,66.0,0.9699676705988233,2335.6821508019666,66.0,nonessential
1526,HNEAP_RS07975,WP_012824456.1,502586707.0,1734142,1735185,1043.0,-,acylamide amidohydrolase,0.5833,21,0.9999965548338764,2407.991704039974,72.0,0.9999957134332338,2407.989677947227,70.0,nonessential
1527,HNEAP_RS07980,WP_012824457.1,502586708.0,1735326,1736015,689.0,-,urea ABC transporter ATP-binding subunit UrtE,0.5464,6,0.7370335095035199,1774.7766908844758,30.0,0.7879965235967248,1897.4956288209132,30.0,nonessential
1528,HNEAP_RS07985,WP_012824458.1,502586709.0,1736031,1736774,743.0,-,urea ABC transporter ATP-binding protein UrtD,0.5376,8,0.5124027236356383,1233.865758514617,29.0,0.5791334159273014,1394.5532655529416,29.0,nonessential
1529,HNEAP_RS07990,WP_012824459.1,502586710.0,1736771,1737925,1154.0,-,urea ABC transporter permease subunit UrtC,0.5377,27,0.6094139648697007,1467.4688274062391,47.0,0.6326136145999692,1523.333583956726,46.0,nonessential
1530,HNEAP_RS07995,WP_041600907.1,753845290.0,1737936,1738859,923.0,-,urea ABC transporter permease subunit UrtB,0.5281,26,0.9999681975599989,2407.9234197244773,62.0,0.9998580084984331,2407.6580844642267,58.0,nonessential
1531,HNEAP_RS08000,WP_041600908.1,753845291.0,1738955,1740163,1208.0,-,urea ABC transporter substrate-binding protein,0.5318,35,0.9999999999977843,2407.9999999946644,101.0,0.9999999999770831,2407.999999944816,96.0,nonessential
1532,HNEAP_RS08005,WP_012824462.1,502586713.0,1740873,1742108,1235.0,+,acetamidase/formamidase family protein,0.5316,24,0.9718811042755671,2340.2896990955655,62.0,0.9772280655067623,2353.1651817402835,61.0,nonessential
1533,HNEAP_RS12555,WP_012824463.1,502586714.0,1742181,1742513,332.0,+,zinc ribbon domain-containing protein,0.5676,5,0.9961190320562072,2398.654629191347,23.0,0.9973412077399686,2401.597628237844,23.0,nonessential
1534,HNEAP_RS08015,WP_012824464.1,502586716.0,1742608,1743333,725.0,+,hypothetical protein,0.4725,39,0.9893564588417872,2382.3703528910237,41.0,0.9934311612817018,2392.182236366338,41.0,nonessential
1535,HNEAP_RS08020,WP_012824466.1,502586718.0,1744293,1745276,983.0,-,oxidoreductase,0.5122,41,0.9999999999999999,2407.9999999999995,99.0,0.9999999999999992,2407.999999999998,94.0,nonessential
1536,HNEAP_RS08025,WP_012824467.1,502586719.0,1745327,1745968,641.0,-,TetR family transcriptional regulator,0.4922,23,0.983588778719348,2368.48177915619,36.0,0.9892960913072132,2382.2249878677694,36.0,nonessential
1537,HNEAP_RS08030,WP_012824468.1,502586720.0,1746091,1746837,746.0,-,NAD(P)-dependent oxidoreductase,0.5248,18,0.9265924490293787,2231.234617262744,37.0,0.9266513086404334,2231.3763512061637,36.0,nonessential
1538,HNEAP_RS08035,WP_012824469.1,502586721.0,1747004,1747567,563.0,-,TetR/AcrR family transcriptional regulator,0.5372,15,0.7577621927265344,1824.691360085495,25.0,0.8021007575925402,1931.4586242828368,25.0,nonessential
1539,HNEAP_RS08040,WP_012824470.1,502586722.0,1747651,1748118,467.0,+,DUF1348 domain-containing protein,0.5192,16,0.5113395019040374,1231.305520584922,18.0,0.4689699117133287,1129.2795474056954,17.0,nonessential
1540,HNEAP_RS08050,WP_012824471.1,502586723.0,1748600,1749133,533.0,-,lytic transglycosylase,0.5056,11,0.212017175164516,510.5373577961545,17.0,0.42235110863516806,1017.0214695934847,19.0,nonessential
1541,HNEAP_RS08055,WP_012824472.1,502586724.0,1749144,1750337,1193.0,-,TraB family protein,0.5578,35,0.9998517908227635,2407.6431123012144,73.0,0.9999798497914761,2407.9514782978745,75.0,nonessential
1542,HNEAP_RS08060,WP_012824474.1,502586726.0,1750495,1752537,2042.0,-,DNA topoisomerase III,0.5409,32,0.9930689791858388,2391.3101018795,103.0,0.9868298619261713,2376.2863075182204,98.0,nonessential
1543,HNEAP_RS12285,WP_012824475.1,502586727.0,1752548,1753081,533.0,-,conjugative transfer signal peptidase TraF,0.5449,16,0.9948095425113164,2395.50137836725,33.0,0.9942090457883737,2394.055382258404,32.0,nonessential
1544,HNEAP_RS08070,WP_012824476.1,502586728.0,1753244,1754725,1481.0,-,P-type conjugative transfer protein TrbL,0.5439,34,0.779421620264476,1876.8472615968583,64.0,0.8109850675538073,1952.852042669568,63.0,nonessential
1545,HNEAP_RS08075,WP_012824477.1,502586729.0,1754722,1755015,293.0,-,hypothetical protein,0.5068,6,0.8745078985651746,2105.8150197449404,15.0,0.8960441569659379,2157.6743299739783,15.0,nonessential
1546,HNEAP_RS08080,WP_012824478.1,502586730.0,1755046,1755798,752.0,-,P-type conjugative transfer protein TrbJ,0.5193,12,0.9878918868996996,2378.8436636544766,42.0,0.98198083176671,2364.6098428942378,40.0,nonessential
1547,HNEAP_RS08085,WP_012824479.1,502586731.0,1755875,1758334,2459.0,-,type IV transporter system CagE/TrbE/VirB,0.5346,62,0.9997953511342669,2407.5072055313144,133.0,0.9994989705767736,2406.7935211488707,127.0,nonessential
1548,HNEAP_RS08090,WP_012824480.1,502586732.0,1758340,1758636,296.0,-,conjugal transfer protein TrbD,0.4983,11,0.2599469632630825,625.9522875375026,9.0,0.41056776851212534,988.6471865771978,10.0,nonessential
1549,HNEAP_RS08095,WP_012824481.1,502586733.0,1758692,1759111,419.0,-,conjugal transfer protein TrbC,0.5571,8,0.6907320333613336,1663.2827363340914,18.0,0.7346440408786923,1769.022850435891,18.0,nonessential
1550,HNEAP_RS08100,WP_012824482.1,502586734.0,1759192,1759692,500.0,-,N-acetyltransferase,0.5908,9,0.9711584322255026,2338.5495047990103,28.0,0.9670816186574788,2328.732537727209,27.0,nonessential
1551,HNEAP_RS08105,WP_012824483.1,502586735.0,1759689,1759970,281.0,-,DUF1778 domain-containing protein,0.6064,2,0.7705795929048417,1855.5556597148588,13.0,0.7110581444959342,1712.2280119462096,12.0,nonessential
1552,HNEAP_RS08110,WP_012824484.1,502586736.0,1760053,1761093,1040.0,-,P-type conjugative transfer ATPase TrbB,0.5437,23,0.9997090817579187,2407.2994688730682,64.0,0.9998714643905003,2407.6904862523247,64.0,nonessential
1553,HNEAP_RS08115,WP_041600406.1,753844789.0,1761166,1762536,1370.0,-,hypothetical protein,0.4843,36,0.9167123999659873,2207.4434591180975,64.0,0.947222735739984,2280.9123476618815,64.0,nonessential
1554,HNEAP_RS08120,WP_012824487.1,502586739.0,1763109,1763381,272.0,-,type II toxin-antitoxin system RelE/ParE family toxin,0.5385,4,0.8729896412519822,2102.159056134773,14.0,0.8319241141892302,2003.2732669676664,13.0,nonessential
1555,HNEAP_RS08125,WP_012824488.1,502586740.0,1763365,1763589,224.0,-,TraY domain-containing protein,0.5511,4,0.00011489787385085696,0.27667408023286355,0.0,0.00015174523196942856,0.365402518582384,0.0,ambiguous
1556,HNEAP_RS08130,WP_081441129.1,1174219948.0,1763644,1764135,491.0,-,helix-turn-helix domain-containing protein,0.4898,20,5.247115694144566e-07,0.0012635054591500115,2.0,9.08868654628475e-07,0.002188555720345368,2.0,essential
1557,HNEAP_RS08135,WP_081441130.1,1174219949.0,1764374,1764838,464.0,+,hypothetical protein,0.5355,11,0.773603876218322,1862.8381339337195,21.0,0.8126105633541881,1956.7662365568851,21.0,nonessential
1558,HNEAP_RS12290,WP_012824491.1,502586744.0,1764943,1766412,1469.0,+,hypothetical protein,0.4918,37,0.9577510033561423,2306.2644160815908,71.0,0.957060330925355,2304.601276868255,69.0,nonessential
1559,HNEAP_RS08145,WP_012824492.1,502586745.0,1766800,1768263,1463.0,+,hypothetical protein,0.4577,46,0.3725449374532221,897.0882093873588,55.0,0.46394435682197505,1117.178011227316,55.0,nonessential
1560,HNEAP_RS08150,WP_012824493.1,502586746.0,1768331,1769200,869.0,+,DNA methyltransferase,0.4345,47,4.356370615946308e-12,1.049014044319871e-08,3.0,5.4771559252550196e-14,1.3188991468014087e-10,1.0,essential
1561,HNEAP_RS08155,WP_012824494.1,502586747.0,1769593,1769883,290.0,+,addiction module antidote protein  HigA family,0.5395,10,0.9272782744686865,2232.886084920597,16.0,0.941563624918256,2267.2852088031605,16.0,nonessential
1562,HNEAP_RS08165,WP_041600407.1,753844790.0,1770698,1771276,578.0,-,hypothetical protein,0.4508,14,0.7151005031659508,1721.9620116236094,25.0,0.6955602994872039,1674.909201165187,24.0,nonessential
1563,HNEAP_RS08170,WP_012824497.1,502586750.0,1771307,1771678,371.0,-,hypothetical protein,0.5349,6,0.0029456364986544703,7.093092688759964,5.0,0.004034541230083547,9.71517528204118,5.0,nonessential
1564,HNEAP_RS08175,WP_012824498.1,502586751.0,1771804,1772277,473.0,-,RES domain-containing protein,0.5063,10,0.9972295413796745,2401.328735642256,31.0,0.9982554683159507,2403.7991677048094,31.0,nonessential
1565,HNEAP_RS12295,WP_012824499.1,502586752.0,1772277,1772777,500.0,-,hypothetical protein,0.523,10,0.9999999986383092,2407.999996721049,50.0,0.9999999985887137,2407.9999966016226,49.0,nonessential
1566,HNEAP_RS08185,WP_041600408.1,753844791.0,1772774,1772956,182.0,-,hypothetical protein,0.4426,8,0.564819469523747,1360.0852826131827,7.0,0.8338846260255016,2007.994179469408,9.0,nonessential
1567,HNEAP_RS08190,WP_041600409.1,753844792.0,1773355,1773663,308.0,+,hypothetical protein,0.5081,11,0.31963088667213224,769.6711751064944,10.0,0.3585217057655346,863.3202674834073,10.0,nonessential
1568,HNEAP_RS08195,WP_012824501.1,502586754.0,1773650,1773862,212.0,+,hypothetical protein,0.4883,10,0.6656827958467952,1602.9641723990828,9.0,0.6985753828764237,1682.1695219664284,9.0,nonessential
1569,HNEAP_RS08200,WP_012824502.1,502586755.0,1773862,1774206,344.0,+,hypothetical protein,0.4928,12,0.9940187706250688,2393.5971996651656,23.0,0.9979490085938789,2403.0612126940605,24.0,nonessential
1570,HNEAP_RS08205,WP_012824503.1,502586756.0,1774266,1775747,1481.0,+,DUF3363 domain-containing protein,0.4919,50,0.8478494399995464,2041.6214515189079,66.0,0.8979313822647067,2162.218768493414,66.0,nonessential
1571,HNEAP_RS08210,WP_012824504.1,502586757.0,1775744,1776370,626.0,+,hypothetical protein,0.488,25,0.9999999994004337,2407.9999985562445,59.0,0.999999999491574,2407.99999877571,58.0,nonessential
1572,HNEAP_RS08215,WP_012824505.1,502586758.0,1776381,1777454,1073.0,+,hypothetical protein,0.4981,21,0.6824720618426985,1643.392724917218,45.0,0.7001997495453753,1686.0809969052639,44.0,nonessential
1573,HNEAP_RS08220,WP_012824506.1,502586759.0,1777459,1778379,920.0,+,hypothetical protein,0.4821,20,0.0840141362357634,202.30604005571826,28.0,0.05830647835517422,140.4019998792595,26.0,nonessential
1574,HNEAP_RS08225,WP_012824507.1,502586760.0,1778404,1778592,188.0,+,hypothetical protein,0.5079,2,0.057136974025743054,137.58583345398927,3.0,0.02288583176200826,55.10908288291589,2.0,nonessential
1575,HNEAP_RS08230,WP_012824508.1,502586761.0,1778690,1779922,1232.0,+,DUF1738 domain-containing protein,0.5166,30,0.9996251802287694,2407.0974339908767,73.0,0.9995888699509419,2407.009998841868,71.0,nonessential
1576,HNEAP_RS08235,WP_012824509.1,502586762.0,1779991,1782462,2471.0,+,TRAG family protein,0.5392,56,0.9999999999999999,2407.9999999999995,193.0,0.9999999999999999,2407.9999999999995,188.0,nonessential
1577,HNEAP_RS08240,WP_012824510.1,502586763.0,1782475,1782915,440.0,+,single-stranded DNA-binding protein,0.542,7,0.8878523700095706,2137.948506983046,22.0,0.8138904473257793,1959.8481971604765,20.0,nonessential
1578,HNEAP_RS08245,WP_012824512.1,502586765.0,1783924,1784445,521.0,+,cysteine hydrolase,0.4387,24,0.9322225816411704,2244.7919765919382,27.0,0.8896859735048838,2142.36382419976,25.0,nonessential
1579,HNEAP_RS08250,WP_012824513.1,502586766.0,1784505,1785002,497.0,+,dihydrofolate reductase,0.5221,13,0.9834199799826243,2368.0753117981594,29.0,0.9809754596722912,2362.188906890877,28.0,nonessential
1580,HNEAP_RS08255,WP_041600487.1,753844870.0,1785105,1785476,371.0,+,VOC family protein,0.4194,16,2.9846385027129754e-07,0.0007187009514532845,0.0,4.7312054556039764e-07,0.0011392742737094375,0.0,essential
1581,HNEAP_RS08260,WP_012824514.1,502586767.0,1785473,1785763,290.0,+,DUF1330 domain-containing protein,0.3711,14,0.0001030303302763804,0.24809703530552402,1.0,0.00014343112767028178,0.34538215543003853,1.0,nonessential
1582,HNEAP_RS08265,WP_012824515.1,502586768.0,1785910,1786713,803.0,+,hypothetical protein,0.3408,51,0.059937672181572754,144.3299146132272,23.0,0.08256723087457132,198.82189194596774,23.0,nonessential
1583,HNEAP_RS08270,WP_012824516.1,502586769.0,1786885,1787223,338.0,+,hypothetical protein,0.3835,11,1.7001576640744478e-05,0.040939796550912705,1.0,2.5113726165061745e-05,0.060473852605468684,1.0,ambiguous
1584,HNEAP_RS08275,WP_012824517.1,502586770.0,1787296,1787922,626.0,+,ATPase,0.5295,19,0.9712902685183984,2338.8669665923035,34.0,0.954527336524501,2298.5018263509983,32.0,nonessential
1585,HNEAP_RS12570,WP_012824518.1,502586771.0,1787963,1788376,413.0,+,aldehyde-activating protein,0.4348,13,0.974099783311494,2345.632278214078,24.0,0.9483750897530163,2283.687216125263,22.0,nonessential
1586,HNEAP_RS08280,WP_012824519.1,502586772.0,1788485,1788841,356.0,+,hypothetical protein,0.4874,14,0.9952886053592915,2396.654961705174,24.0,0.9937125089740042,2392.859721609402,23.0,nonessential
1587,HNEAP_RS08285,WP_012824520.1,502586773.0,1788914,1790203,1289.0,+,hypothetical protein,0.4279,54,0.2570806942545199,619.0503117648839,46.0,0.33220119148261457,799.9404690901358,46.0,nonessential
1588,HNEAP_RS08290,WP_012824521.1,502586774.0,1790286,1790894,608.0,+,transglutaminase family protein,0.4943,22,0.9037772475587618,2176.2956121214984,30.0,0.9281251973628994,2234.925475249862,30.0,nonessential
1589,HNEAP_RS08295,WP_012824522.1,502586775.0,1790917,1791396,479.0,+,N-acetyltransferase,0.5312,16,5.6476343145133e-06,0.013599503429348027,3.0,1.3889158970954478e-06,0.0033445094802058385,2.0,essential
1590,HNEAP_RS08300,WP_012824523.1,502586776.0,1791488,1791826,338.0,+,hypothetical protein,0.3864,11,1.1357747322371667e-06,0.0027349455552270973,0.0,1.7281259581847268e-06,0.004161327307308822,0.0,essential
1591,HNEAP_RS08305,WP_081441131.1,1174219950.0,1791948,1792640,692.0,+,hypothetical protein,0.5397,14,0.020576148130693066,49.547364698708904,17.0,0.029392539192541894,70.77723437564089,17.0,nonessential
1592,HNEAP_RS08310,WP_012824525.1,502586778.0,1792655,1793671,1016.0,+,P-type conjugative transfer protein TrbG,0.529,29,0.9981798809119674,2403.6171532360177,59.0,0.9990903316519644,2405.8095186179303,59.0,nonessential
1593,HNEAP_RS12300,WP_012824526.1,502586779.0,1793675,1794994,1319.0,+,conjugation TrbI family protein,0.5341,23,0.9860504658189362,2374.409521691998,68.0,0.9850873303085119,2372.090291382897,66.0,nonessential
1594,HNEAP_RS08320,WP_012824527.1,502586780.0,1794991,1795344,353.0,+,hypothetical protein,0.5226,12,0.46120921862920744,1110.5917984591315,13.0,0.39681102750300956,955.520954227247,12.0,nonessential
1595,HNEAP_RS12305,WP_012824528.1,502586781.0,1795341,1796144,803.0,+,ParA family protein,0.5609,21,0.9999999922675774,2407.9999813803265,67.0,0.9999999713600126,2407.9999310349103,64.0,nonessential
1596,HNEAP_RS12310,WP_012824529.1,502586782.0,1796146,1797183,1037.0,+,parB-like partition protein,0.5308,11,0.877121348919135,2112.108208197277,48.0,0.9139034856588097,2200.6795934664137,48.0,nonessential
1597,HNEAP_RS08335,WP_012824530.1,502586783.0,1797490,1797771,281.0,+,hypothetical protein,0.4965,7,0.3195849875209358,769.5606499504133,9.0,0.35666620654508924,858.8522253605748,9.0,nonessential
1598,HNEAP_RS08340,WP_012824531.1,502586784.0,1797768,1797983,215.0,+,hypothetical protein,0.5324,4,0.999846839994792,2407.631190707459,20.0,0.9997210511897351,2407.328291264882,19.0,nonessential
1599,HNEAP_RS08345,WP_081441132.1,1174219951.0,1797913,1799124,1211.0,+,hypothetical protein,0.5454,27,0.9999999999997865,2407.9999999994857,104.0,0.9999999999989814,2407.999999997547,100.0,nonessential
1600,HNEAP_RS08350,WP_012824533.1,502586786.0,1799209,1799694,485.0,+,low molecular weight phosphotyrosine protein phosphatase,0.5514,12,0.6268517521184707,1509.4590191012774,20.0,0.6776928601617938,1631.8844072695993,20.0,nonessential
1601,HNEAP_RS08355,WP_012824534.1,502586787.0,1799717,1801126,1409.0,-,amino acid permease,0.5567,37,0.9988625291660881,2405.26097023194,79.0,0.9963171097832838,2399.1316003581474,74.0,nonessential
1602,HNEAP_RS08360,WP_012824535.1,502586788.0,1801365,1801694,329.0,+,exodeoxyribonuclease VII small subunit,0.5818,2,0.15674022420793693,377.4304598927121,9.0,0.18386326486012616,442.7427417831838,9.0,nonessential
1603,HNEAP_RS08365,WP_081441133.1,1174219952.0,1801519,1802616,1097.0,+,polyprenyl synthetase family protein,0.5883,13,2.3551373150468273e-18,5.67117065463276e-15,1.0,2.0016151076774076e-16,4.819889179287197e-13,2.0,essential
1604,HNEAP_RS08370,WP_012824537.1,502586790.0,1802616,1804547,1931.0,+,1-deoxy-D-xylulose-5-phosphate synthase,0.6056,20,1.0908846387638875e-34,2.6268502101434413e-31,0.0,1.199957689610684e-33,2.889498116582527e-30,0.0,essential
1605,HNEAP_RS08375,WP_012824538.1,502586791.0,1804544,1805002,458.0,+,6-carboxytetrahydropterin synthase QueD,0.5338,6,0.0007768663944925376,1.8706942779380304,6.0,0.001148342778411148,2.765209410414044,6.0,nonessential
1606,HNEAP_RS08380,WP_012824539.1,502586792.0,1805079,1805870,791.0,+,GTP cyclohydrolase I FolE2,0.5619,14,1.2245505641921075e-14,2.9487177585745945e-11,0.0,3.27011129713467e-14,7.874428003500285e-11,0.0,essential
1607,HNEAP_RS08385,WP_012824540.1,502586793.0,1806364,1809240,2876.0,+,PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase,0.4929,82,0.9999801074443847,2407.9520987260785,159.0,0.999990926237352,2407.9781503795434,157.0,nonessential
1608,HNEAP_RS08390,WP_049772509.1,908628476.0,1809202,1810074,872.0,-,TatD family deoxyribonuclease,0.5682,13,0.9999992577233445,2407.9982125978136,65.0,0.9999994577615801,2407.998694289885,64.0,nonessential
1609,HNEAP_RS08395,WP_012824542.1,502586795.0,1810155,1810973,818.0,+,chemotaxis protein MotA,0.5519,12,0.9429206472057002,2270.5529184713264,41.0,0.923506230109257,2223.803002103091,39.0,nonessential
1610,HNEAP_RS08400,WP_012824543.1,502586796.0,1810985,1811956,971.0,+,OmpA/MotB domain-containing protein,0.5648,18,0.9993650945039463,2406.4711475655026,59.0,0.9998236822460758,2407.5754268485503,60.0,nonessential
1611,HNEAP_RS08405,WP_012824544.1,502586797.0,1811977,1812456,479.0,+,HIT family protein,0.5771,8,0.46662912740253865,1123.6429387853132,18.0,0.42552087010366163,1024.6542552096173,17.0,nonessential
1612,HNEAP_RS08410,WP_012824545.1,502586798.0,1812630,1815236,2606.0,+,GGDEF domain-containing protein,0.5313,49,0.9905667677120825,2385.2847766506948,127.0,0.9935331249235597,2392.427764815932,125.0,nonessential
1613,HNEAP_RS08415,WP_012824546.1,502586799.0,1815315,1818137,2822.0,-,DNA polymerase I,0.57,55,0.005499932640817891,13.243837799089482,86.0,0.002906285587996328,6.998335695895158,81.0,nonessential
1614,HNEAP_RS08420,WP_012824547.1,502586800.0,1818287,1819006,719.0,+,TIGR00730 family Rossman fold protein,0.5417,13,0.28765300370255936,692.668432915763,25.0,0.42083169189657466,1013.3627140869518,26.0,nonessential
1615,HNEAP_RS08425,WP_012824548.1,502586801.0,1819169,1820134,965.0,+,homoserine kinase,0.5921,17,1.0658187585116828e-17,2.5664915704961323e-14,0.0,3.5327041077889836e-17,8.506751491555872e-14,0.0,essential
1616,HNEAP_RS08430,WP_012824549.1,502586803.0,1820127,1821128,1001.0,+,tRNA dihydrouridine synthase DusB,0.5978,14,0.9999666374594066,2407.919663002251,66.0,0.9999233501134145,2407.815427073102,63.0,nonessential
1617,HNEAP_RS08435,WP_012824550.1,502586804.0,1821163,1821483,320.0,+,hypothetical protein,0.5732,3,0.00023874520365918533,0.5748984504113183,2.0,4.838345569293039e-05,0.11650736130857639,1.0,nonessential
1618,HNEAP_RS08440,WP_081441134.1,1174219953.0,1821801,1822577,776.0,-,hypothetical protein,0.5869,13,0.9979995396136889,2403.182891389763,47.0,0.9996406246372345,2407.1346241264605,49.0,nonessential
1619,HNEAP_RS08445,WP_012824552.1,502586806.0,1822733,1825996,3263.0,+,diguanylate cyclase,0.5012,89,0.9678746122610546,2330.6420663246195,150.0,0.9865154698239872,2375.529251336161,150.0,nonessential
1620,HNEAP_RS08450,WP_012824553.1,502586807.0,1825993,1827231,1238.0,+,multifunctional CCA addition/repair protein,0.5956,14,1.6834049512237073e-22,4.0536391225466874e-19,0.0,7.831432972052887e-22,1.885809059670335e-18,0.0,essential
1621,HNEAP_RS08455,WP_012824554.1,502586808.0,1827452,1828057,605.0,-,phosphoglycerate mutase,0.5891,7,0.9358635823806754,2253.5595063726664,31.0,0.9315795612233136,2243.2435834257394,30.0,nonessential
1622,HNEAP_RS08460,WP_012824555.1,502586809.0,1828057,1829070,1013.0,-,signaling modulator of AmpD  AmpE,0.5651,16,0.9999955846032972,2407.9893677247396,70.0,0.9999984261190147,2407.9962100945872,70.0,nonessential
1623,HNEAP_RS08465,WP_012824556.1,502586810.0,1829148,1829708,560.0,-,1 6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD,0.5882,13,0.9999999966496486,2407.9999919323536,53.0,0.9999999915812131,2407.9999797275614,51.0,nonessential
1624,HNEAP_RS08470,WP_012824557.1,502586811.0,1829854,1830471,617.0,+,TetR/AcrR family transcriptional regulator,0.5599,7,0.9999777532594962,2407.946429848867,46.0,0.9999550399225928,2407.8917361336034,44.0,nonessential
1625,HNEAP_RS08475,WP_041600410.1,753844793.0,1830480,1830839,359.0,-,hypothetical protein,0.5444,8,0.997325530177736,2401.559876667988,25.0,0.9930560943823078,2391.2790752725973,23.0,nonessential
1626,HNEAP_RS08480,WP_012824559.1,502586813.0,1831059,1831592,533.0,+,hypothetical protein,0.5674,5,0.9999999246806579,2407.999818631024,48.0,0.9999998067967458,2407.999534766564,46.0,nonessential
1627,HNEAP_RS08485,WP_012824560.1,502586814.0,1831681,1832589,908.0,+,EamA/RhaT family transporter,0.5809,14,0.9793515201951146,2358.278460629836,48.0,0.9873346205520926,2377.5017662894393,48.0,nonessential
1628,HNEAP_RS08490,WP_012824561.1,502586815.0,1832656,1833051,395.0,+,4-carboxymuconolactone decarboxylase,0.5732,5,0.7723707068827317,1859.8686621736178,18.0,0.8087173053179182,1947.391271205547,18.0,nonessential
1629,HNEAP_RS08495,WP_012824562.1,502586816.0,1833062,1833664,602.0,-,CinA family protein,0.602,12,0.8772858286646834,2112.504275424558,29.0,0.9063660745244537,2182.5295074548844,29.0,nonessential
1630,HNEAP_RS08500,WP_012824563.1,502586817.0,1833633,1834034,401.0,-,hypothetical protein,0.6169,6,0.9996122256447726,2407.0662393526122,30.0,0.9997677483817518,2407.4407381032584,30.0,nonessential
1631,HNEAP_RS08505,WP_012824564.1,502586818.0,1834027,1834317,290.0,-,thiamine-binding protein,0.5567,6,0.10840342558228455,261.0354488021412,7.0,0.12800463098132284,308.2351514030254,7.0,nonessential
1632,HNEAP_RS08510,WP_012824565.1,502586819.0,1834665,1836878,2213.0,+,peptidase S8,0.5596,57,0.9999216737771548,2407.811390455389,124.0,0.9999259329804464,2407.821646616915,121.0,nonessential
1633,HNEAP_RS08515,WP_041600411.1,753844794.0,1836905,1837279,374.0,+,hypothetical protein,0.5573,9,0.9997426497619514,2407.380300626779,29.0,0.9998458653278788,2407.6288437095322,29.0,nonessential
1634,HNEAP_RS08520,WP_012824567.1,502586821.0,1837347,1837856,509.0,-,DNA damage-inducible protein DinB,0.5176,14,0.9779174257899103,2354.825161302104,29.0,0.98466784568657,2371.0801724132602,29.0,nonessential
1635,HNEAP_RS08530,WP_081441135.1,1174219954.0,1838466,1839569,1103.0,+,PLP-dependent aminotransferase family protein,0.587,23,0.6132268302166444,1476.6502071616796,45.0,0.6333553430513069,1525.119666067547,44.0,nonessential
1636,HNEAP_RS12320,WP_049772513.1,908628480.0,1839630,1839938,308.0,+,hypothetical protein,0.5663,3,0.5498483797517544,1324.0348984422246,12.0,0.4761486706714583,1146.5659989768715,11.0,nonessential
1637,HNEAP_RS08535,WP_012824569.1,502586823.0,1840051,1841190,1139.0,-,23S rRNA (uracil(747)-C(5))-methyltransferase RlmC,0.536,22,0.15400284742587025,370.8388566014956,38.0,0.20724863984282382,499.05472474151975,38.0,nonessential
1638,HNEAP_RS08540,WP_012824570.1,502586824.0,1841339,1843486,2147.0,-,FimV protein,0.5247,42,0.4753902916912053,1144.7398223924224,84.0,0.5447895711000055,1311.8532872088133,83.0,nonessential
1639,HNEAP_RS08545,WP_012824571.1,502586825.0,1843661,1844683,1022.0,-,aspartate-semialdehyde dehydrogenase,0.5621,23,1.0596768940555314e-18,2.5517019608857197e-15,0.0,3.769965998327436e-18,9.078078123972465e-15,0.0,essential
1640,HNEAP_RS08550,WP_012824572.1,502586826.0,1844757,1845830,1073.0,-,3-isopropylmalate dehydrogenase,0.5689,21,1.6130608724618768e-12,3.8842505808881995e-09,6.0,5.07720197560235e-12,1.2225902357250459e-08,6.0,essential
1641,HNEAP_RS08555,WP_012824573.1,502586827.0,1845849,1846775,926.0,-,permease,0.562,16,0.9994405036550689,2406.652732801406,57.0,0.9979485782946578,2403.060176533536,53.0,nonessential
1642,HNEAP_RS08560,WP_012824574.1,502586828.0,1846791,1847441,650.0,-,3-isopropylmalate dehydratase small subunit,0.5438,8,1.3325808702880329e-08,3.208854735653583e-05,3.0,2.2395447358636448e-10,5.392823723959656e-07,1.0,essential
1643,HNEAP_RS08565,WP_012824575.1,502586829.0,1847476,1848882,1406.0,-,3-isopropylmalate dehydratase large subunit,0.6041,15,1.8681966733036633e-25,4.498617589315221e-22,0.0,1.070723971024645e-24,2.5783033222273454e-21,0.0,essential
1644,HNEAP_RS08570,WP_081441136.1,1174219955.0,1848980,1849891,911.0,+,LysR family transcriptional regulator,0.58,10,0.9999999998263497,2407.9999995818503,78.0,0.9999999997586261,2407.9999994187715,76.0,nonessential
1645,HNEAP_RS08575,WP_012824577.1,502586831.0,1849945,1851036,1091.0,-,alkene reductase,0.5769,24,0.9999999486413917,2407.999876328471,81.0,0.9999997656005472,2407.9994355661174,77.0,nonessential
1646,HNEAP_RS08580,WP_081441190.1,1174220009.0,1851118,1851483,365.0,-,DUF2288 domain-containing protein,0.5847,3,0.9638200650423762,2320.878716622042,21.0,0.9845500264569175,2370.7964637082573,22.0,nonessential
1647,HNEAP_RS08585,WP_012824579.1,502586833.0,1851605,1852003,398.0,+,cupin,0.5464,7,0.022530677940511824,54.25387248075247,8.0,0.05662754233844691,136.35912195098015,9.0,nonessential
1648,HNEAP_RS08590,WP_012824580.1,502586834.0,1852020,1852301,281.0,+,hypothetical protein,0.4823,8,0.12852189327548005,309.48071900735596,7.0,0.15025856794077908,361.82263160139604,7.0,nonessential
1649,HNEAP_RS08595,WP_012824581.1,502586835.0,1852443,1853213,770.0,-,3-deoxy-manno-octulosonate cytidylyltransferase,0.5953,10,2.8663054764931637e-14,6.902063587395538e-11,0.0,7.457323747395886e-14,1.7957235583729295e-10,0.0,essential
1650,HNEAP_RS08600,WP_012824582.1,502586836.0,1853210,1853428,218.0,-,hypothetical protein,0.5251,5,0.000146500581872582,0.35277340114917743,0.0,0.0001920465965167608,0.46244820441235995,0.0,ambiguous
1651,HNEAP_RS08605,WP_012824583.1,502586837.0,1853499,1854521,1022.0,-,tetraacyldisaccharide 4'-kinase,0.5953,15,1.425977127637726e-14,3.4337529233516444e-11,3.0,4.622811883697415e-14,1.1131731015943376e-10,3.0,essential
1652,HNEAP_RS08610,WP_012824584.1,502586838.0,1854522,1856327,1805.0,-,lipid A export permease/ATP-binding protein MsbA,0.5853,31,1.3563342917545304e-30,3.266052974544909e-27,1.0,1.2364905981907655e-29,2.9774693604433636e-26,1.0,essential
1653,HNEAP_RS08615,WP_012824586.1,502586840.0,1856473,1856871,398.0,-,biopolymer transporter ExbD,0.5489,2,0.9999979101163948,2407.994967560279,36.0,0.9999989623847569,2407.9975014224947,36.0,nonessential
1654,HNEAP_RS08620,WP_012824587.1,502586841.0,1856882,1857505,623.0,-,MotA/TolQ/ExbB proton channel family protein,0.5737,12,0.9995942536354634,2407.0229627541958,42.0,0.9992381415069569,2406.165444748752,40.0,nonessential
1655,HNEAP_RS08625,WP_012824588.1,502586842.0,1857552,1859426,1874.0,-,DUF4140 domain-containing protein,0.5509,32,0.9039346995657154,2176.674756554243,85.0,0.9427023331482289,2270.027218220935,85.0,nonessential
1656,HNEAP_RS08630,WP_012824589.1,502586843.0,1859484,1860587,1103.0,-,3-deoxy-7-phosphoheptulonate synthase,0.5634,15,4.323669365224912e-17,1.0411395831461588e-13,2.0,1.5985317712734775e-16,3.8492645052265337e-13,2.0,essential
1657,HNEAP_RS08635,WP_012824590.1,502586844.0,1860886,1861770,884.0,-,nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase,0.5672,12,0.9991158998937136,2405.8710869440624,54.0,0.9995576442082191,2406.9348072533917,54.0,nonessential
1658,HNEAP_RS08640,WP_012824591.1,502586845.0,1861767,1865807,4040.0,-,TIGR02099 family protein,0.5659,62,0.9981645350978114,2403.58020051553,197.0,0.9972680416362769,2401.4214442601547,190.0,nonessential
1659,HNEAP_RS08645,WP_012824592.1,502586846.0,1865898,1867388,1490.0,-,Rne/Rng family ribonuclease,0.5553,26,0.47444897082447474,1142.4731217453352,58.0,0.4088033295347548,984.3984175196896,55.0,nonessential
1660,HNEAP_RS08650,WP_012824593.1,502586847.0,1867424,1868047,623.0,-,septum formation inhibitor Maf,0.5817,11,0.9591697734627752,2309.680814498363,33.0,0.9715189666194516,2339.4176716196393,33.0,nonessential
1661,HNEAP_RS08655,WP_012824594.1,502586848.0,1868048,1868518,470.0,-,23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH,0.6051,4,0.1630887867211498,392.7177984245287,14.0,0.0840965549404475,202.5045042965976,12.0,nonessential
1662,HNEAP_RS08660,WP_012824595.1,502586849.0,1868539,1869060,521.0,-,ribosome silencing factor,0.5613,9,0.9988922020190351,2405.3324224618364,35.0,0.999347405407533,2406.4285522213395,35.0,nonessential
1663,HNEAP_RS08665,WP_012824596.1,502586850.0,1869085,1869771,686.0,-,nicotinate-nucleotide adenylyltransferase,0.6055,9,2.6585698516483035e-08,6.401836202769115e-05,4.0,3.139957546361562e-07,0.0007561017771638641,5.0,essential
1664,HNEAP_RS08670,WP_012824597.1,502586851.0,1869752,1871029,1277.0,-,glutamate-5-semialdehyde dehydrogenase,0.5947,23,1.2061254431364842e-17,2.904350067072654e-14,4.0,5.413231782546807e-16,1.303506213237271e-12,5.0,essential
1665,HNEAP_RS08675,WP_012824598.1,502586852.0,1871155,1872162,1007.0,-,DNA polymerase III subunit delta,0.6141,11,8.290606069417359e-17,1.9963779415157002e-13,1.0,2.806679746446849e-16,6.758484829444013e-13,1.0,essential
1666,HNEAP_RS08680,WP_012824599.1,502586853.0,1872166,1872729,563.0,-,lipoprotein B,0.5745,14,0.355756831555314,856.6624503851962,20.0,0.125922459511598,303.22128250392797,16.0,nonessential
1667,HNEAP_RS08685,WP_041600945.1,753845328.0,1872733,1875186,2453.0,-,leucine--tRNA ligase,0.5823,54,7.192812458363274e-44,1.7320292399738763e-40,0.0,1.5128648102997184e-42,3.6429784632017216e-39,0.0,essential
1668,HNEAP_RS08690,WP_012824602.1,502586856.0,1875519,1875908,389.0,+,hypothetical protein,0.5231,10,0.053361829805132266,128.4952861707585,9.0,0.06689937793114799,161.09370205820434,9.0,nonessential
1669,HNEAP_RS08695,WP_012824604.1,502586858.0,1876184,1876792,608.0,-,superoxide dismutase,0.5583,8,2.0256346713037446e-11,4.877728288499417e-08,0.0,4.30978044445086e-11,1.0377951310237672e-07,0.0,essential
1670,HNEAP_RS08700,WP_041600413.1,753844796.0,1877126,1877818,692.0,-,peptidase,0.6147,7,0.9701447177281793,2336.1084802894557,37.0,0.969727172363792,2335.1030310520114,36.0,nonessential
1671,HNEAP_RS08705,WP_012824606.1,502586860.0,1877815,1880892,3077.0,-,translocation/assembly module TamB,0.5565,64,0.999999998615319,2407.9999966656883,191.0,0.999999998969463,2407.999997518467,187.0,nonessential
1672,HNEAP_RS08710,WP_012824607.1,502586861.0,1880953,1881738,785.0,-,hypothetical protein,0.5509,19,0.9999932186909467,2407.9836706077995,57.0,0.9999782918901315,2407.9477268714368,54.0,nonessential
1673,HNEAP_RS08715,WP_041600414.1,753844797.0,1881738,1883546,1808.0,-,outer membrane protein assembly factor,0.5721,41,0.9189408682611833,2212.8096107729293,83.0,0.9244778265685502,2226.1426063770687,81.0,nonessential
1674,HNEAP_RS08720,WP_012824609.1,502586863.0,1883524,1885440,1916.0,-,DNA topoisomerase IV subunit B,0.5968,26,1.7190299243618694e-29,4.1394240578633814e-26,3.0,3.27872458291539e-27,7.895168795660259e-24,4.0,essential
1675,HNEAP_RS08725,WP_012824610.1,502586864.0,1885588,1886556,968.0,-,EamA family transporter,0.5913,16,0.9809901434564583,2362.2242654431516,51.0,0.988595948537665,2380.5390440786973,51.0,nonessential
1676,HNEAP_RS08730,WP_012824611.1,502586865.0,1886665,1887528,863.0,+,thioredoxin,0.5521,4,0.11706756559477602,281.89869795222063,27.0,0.15524422183600356,373.8280861810966,27.0,nonessential
1677,HNEAP_RS08735,WP_012824612.1,502586866.0,1887667,1890717,3050.0,-,ribonuclease Rne/Rng family,0.5824,43,0.3070445239607229,739.3632136974207,115.0,0.32609377186786975,785.2338026578303,112.0,nonessential
1678,HNEAP_RS08745,WP_081441137.1,1174219956.0,1891270,1892352,1082.0,+,RluA family pseudouridine synthase,0.5836,8,0.9999999999999999,2407.9999999999995,114.0,0.9999999999999999,2407.9999999999995,111.0,nonessential
1679,HNEAP_RS08750,WP_012824614.1,502586869.0,1892349,1893053,704.0,+,haloacid dehalogenase,0.5645,13,0.999740901048998,2407.376089725987,47.0,0.9997560711675375,2407.4126193714305,46.0,nonessential
1680,HNEAP_RS08755,WP_012824615.1,502586870.0,1893050,1894102,1052.0,+,signal peptide peptidase SppA,0.5622,20,0.9743462058884428,2346.2256637793703,54.0,0.9968703392225028,2400.463776847787,58.0,nonessential
1681,HNEAP_RS08760,WP_012824616.1,502586871.0,1894135,1894449,314.0,+,ATP-dependent Clp protease adapter ClpS,0.5111,10,0.2958877607168844,712.4977278062576,10.0,0.1443020194080381,347.4792627345558,8.0,nonessential
1682,HNEAP_RS08765,WP_012824617.1,502586872.0,1894473,1896749,2276.0,+,ATP-dependent Clp protease ATP-binding subunit ClpA,0.5683,29,0.7144197970011757,1720.3228711788313,95.0,0.7756299429519781,1867.7169026283632,94.0,nonessential
1683,HNEAP_RS08770,WP_012824618.1,502586873.0,1896888,1897106,218.0,-,translation initiation factor IF-1,0.4795,11,0.000146500581872582,0.35277340114917743,0.0,0.0001920465965167608,0.46244820441235995,0.0,ambiguous
1684,HNEAP_RS08775,WP_012824619.1,502586874.0,1897241,1897813,572.0,+,nitroreductase,0.5462,11,0.18551192696211696,446.71272012477766,18.0,0.22627839301445388,544.8783703788049,18.0,nonessential
1685,HNEAP_RS08780,WP_012824620.1,502586875.0,1897814,1899013,1199.0,-,hypothetical protein,0.545,26,0.3867027052306324,931.1801141953628,45.0,0.35233183768310405,848.4150651409145,43.0,nonessential
1686,HNEAP_RS08785,WP_012824621.1,502586876.0,1899062,1900042,980.0,-,hypothetical protein,0.525,17,0.23978450345248908,577.4010843135937,34.0,0.36423282543589086,877.0726436496252,35.0,nonessential
1687,HNEAP_RS08790,WP_012824622.1,502586877.0,1900498,1901439,941.0,-,flagellar hook-associated protein 3,0.5074,23,0.9999951793749696,2407.9883919349268,66.0,0.9999933568520426,2407.9840032997186,64.0,nonessential
1688,HNEAP_RS08795,WP_012824623.1,502586878.0,1901452,1903101,1649.0,-,flagellar hook-associated protein FlgK,0.5594,36,0.9999886746976676,2407.9727286719835,101.0,0.999998055298474,2407.9953171587254,102.0,nonessential
1689,HNEAP_RS08800,WP_081441138.1,1174219957.0,1903319,1904533,1214.0,-,flagellar assembly peptidoglycan hydrolase FlgJ,0.5638,15,0.9999999999999547,2407.999999999891,106.0,0.9999999999999972,2407.999999999993,107.0,nonessential
1690,HNEAP_RS08805,WP_041600949.1,753845332.0,1904556,1905677,1121.0,-,flagellar basal body P-ring protein FlgI,0.5775,20,0.9998191719467924,2407.564566047876,69.0,0.9997864381215927,2407.485742996795,67.0,nonessential
1691,HNEAP_RS08810,WP_012824626.1,502586881.0,1905692,1906384,692.0,-,flagellar basal body L-ring protein FlgH,0.5541,16,0.936726232436885,2255.6367677080193,35.0,0.9552139065707267,2300.15508702231,35.0,nonessential
1692,HNEAP_RS08815,WP_012824627.1,502586882.0,1906408,1907196,788.0,-,flagellar basal-body rod protein FlgG,0.5513,19,0.9990311522184246,2405.6670145419666,49.0,0.9985086725940082,2404.408883606372,47.0,nonessential
1693,HNEAP_RS08820,WP_012824628.1,502586883.0,1907207,1907950,743.0,-,flagellar basal-body rod protein FlgF,0.5793,11,0.9998542838128945,2407.64911542145,50.0,0.9999299110039493,2407.83122569751,50.0,nonessential
1694,HNEAP_RS08825,WP_012824629.1,502586884.0,1908360,1909616,1256.0,-,flagellar hook protein FlgE,0.5553,35,0.9993615207820433,2406.4625420431603,73.0,0.9975044215792856,2401.9906471629197,68.0,nonessential
1695,HNEAP_RS08830,WP_012824630.1,502586885.0,1909670,1910407,737.0,-,flagellar hook capping protein,0.5786,16,0.9999999999999059,2407.999999999773,75.0,0.9999999999999403,2407.9999999998563,74.0,nonessential
1696,HNEAP_RS08835,WP_012824631.1,502586886.0,1910420,1910821,401.0,-,flagellar basal body rod protein FlgC,0.5323,12,0.9999644239826145,2407.9143329501358,33.0,0.9999805578401465,2407.9531832790726,33.0,nonessential
1697,HNEAP_RS08840,WP_012824632.1,502586887.0,1910835,1911233,398.0,-,flagellar basal body rod protein FlgB,0.5489,12,0.7627018782212707,1836.5861227568198,18.0,0.7240325542320971,1743.4703905908898,17.0,nonessential
1698,HNEAP_RS08845,WP_012824633.1,502586888.0,1911377,1912651,1274.0,+,HlyC/CorC family transporter,0.5702,17,0.999999999999994,2407.9999999999854,112.0,0.9999999999998549,2407.9999999996508,106.0,nonessential
1699,HNEAP_RS08850,WP_012824634.1,502586889.0,1912651,1914033,1382.0,+,DNA repair protein RadA,0.6067,20,0.15530732367723993,373.98003541479375,47.0,0.17496388631169976,421.31303823857303,46.0,nonessential
1700,HNEAP_RS12325,WP_012824636.1,502586891.0,1914334,1914729,395.0,-,zinc ribbon domain-containing protein,0.5202,9,0.13868479284878105,333.95298117986476,11.0,0.16633619863889068,400.53756632244875,11.0,nonessential
1701,HNEAP_RS08860,WP_012824637.1,502586892.0,1915050,1915481,431.0,+,hypothetical protein,0.5301,10,0.0226809857166369,54.61581360566166,9.0,0.055898345633635355,134.60321628579393,10.0,nonessential
1702,HNEAP_RS08865,WP_012824638.1,502586893.0,1915574,1916269,695.0,-,electron transport complex subunit RsxE,0.5575,11,0.0029383932121783904,7.075650854925564,14.0,0.0045819127222719355,11.03324583523082,14.0,nonessential
1703,HNEAP_RS08870,WP_012824639.1,502586894.0,1916262,1917032,770.0,-,RnfABCDGE type electron transport complex subunit G,0.5422,14,1.6879459593718771e-10,4.06457387016748e-07,3.0,3.1851434163617887e-09,7.669825346599188e-06,4.0,essential
1704,HNEAP_RS08875,WP_012824640.1,502586895.0,1917043,1918092,1049.0,-,electron transport complex subunit RsxD,0.5905,13,1.306124351989284e-10,3.1451474395901957e-07,8.0,3.7526552338207014e-10,9.036393803040249e-07,8.0,essential
1705,HNEAP_RS08880,WP_012824641.1,502586896.0,1918089,1919792,1703.0,-,electron transport complex subunit RsxC,0.6033,31,1.7176445906613366e-11,4.136088174312499e-08,21.0,2.259703195419634e-11,5.441365294570479e-08,20.0,essential
1706,HNEAP_RS08885,WP_012824642.1,502586897.0,1919785,1920363,578.0,-,electron transport complex subunit RsxB,0.5769,7,6.826497077715092e-11,1.6438204963137943e-07,0.0,1.399306822201934e-10,3.3695308278622574e-07,0.0,essential
1707,HNEAP_RS08890,WP_012824643.1,502586898.0,1920363,1920944,581.0,-,electron transport complex subunit RsxA,0.5172,14,1.5121105223006458e-09,3.641162137699955e-06,1.0,3.017726485122633e-09,7.2666853761753e-06,1.0,essential
1708,HNEAP_RS08895,WP_012824644.1,502586899.0,1921119,1923131,2012.0,-,NADH-ubiquinone oxidoreductase,0.5827,29,0.9987381557690342,2404.9614790918345,107.0,0.9973370203628416,2401.5875450337226,102.0,nonessential
1709,HNEAP_RS08900,WP_012824645.1,502586900.0,1923121,1923945,824.0,-,NADH ubiquinone oxidoreductase,0.5745,15,0.9999856505090007,2407.9654464256737,58.0,0.9999577318204693,2407.89821822369,55.0,nonessential
1710,HNEAP_RS08905,WP_012824646.1,502586901.0,1923959,1925515,1556.0,-,NADH-quinone oxidoreductase subunit D,0.5748,29,0.9999644881274199,2407.914487410827,94.0,0.9999692299838467,2407.925905801103,92.0,nonessential
1711,HNEAP_RS08910,WP_041600955.1,753845338.0,1925502,1926977,1475.0,-,NADH dehydrogenase,0.5847,33,0.9999954109212659,2407.988949498408,94.0,0.9999931138380427,2407.9834181220067,91.0,nonessential
1712,HNEAP_RS08915,WP_012824648.1,502586903.0,1926980,1927660,680.0,-,hydrogenase,0.5228,13,0.025279023038340367,60.8718874763236,17.0,0.03561779142779303,85.76764175812562,17.0,nonessential
1713,HNEAP_RS08920,WP_012824649.1,502586904.0,1927674,1928618,944.0,-,formate hydrogenlyase,0.5471,19,0.9998931014410176,2407.7425882699704,61.0,0.9997472634647809,2407.3914104231926,58.0,nonessential
1714,HNEAP_RS08925,WP_049772585.1,908628552.0,1928871,1929698,827.0,-,phosphate ABC transporter ATP-binding protein PstB,0.5085,23,1.0025253688525481e-13,2.4140810881969356e-10,1.0,7.958169183831778e-15,1.916327139466692e-11,0.0,essential
1715,HNEAP_RS08930,WP_012824651.1,502586906.0,1929791,1930633,842.0,-,phosphate ABC transporter  permease protein PstA,0.5243,22,4.519336841367609e-09,1.0882563114013203e-05,6.0,2.667240258971592e-10,6.422714543603593e-07,4.0,essential
1716,HNEAP_RS08935,WP_012824652.1,502586907.0,1930649,1931626,977.0,-,phosphate ABC transporter permease subunit PstC,0.5225,25,5.6101386814338165e-15,1.350921394489263e-11,2.0,2.3752585067189874e-12,5.719622484179322e-09,4.0,essential
1717,HNEAP_RS08940,WP_012824653.1,502586908.0,1931749,1932789,1040.0,-,phosphate ABC transporter substrate-binding protein PstS,0.5053,20,7.952014687304766e-14,1.9148451367029876e-10,4.0,2.4001332893484594e-14,5.77952096075109e-11,3.0,essential
1718,HNEAP_RS08945,WP_012824654.1,502586909.0,1933466,1934389,923.0,+,hypothetical protein,0.539,28,0.9815710551943112,2363.6231009079015,49.0,0.9888396155612094,2381.1257942713924,49.0,nonessential
1719,HNEAP_RS08950,WP_012824655.1,502586910.0,1934398,1934952,554.0,+,FMN-binding protein,0.573,10,0.9176359820822542,2209.667444854068,28.0,0.9383925594314977,2259.6492831110463,28.0,nonessential
1720,HNEAP_RS08955,WP_012824656.1,502586911.0,1934949,1935788,839.0,+,FAD:protein FMN transferase,0.6321,6,0.9872090065918685,2377.1992878732194,46.0,0.973723523547662,2344.72624470277,43.0,nonessential
1721,HNEAP_RS08960,WP_012824657.1,502586912.0,1935792,1936238,446.0,+,hypothetical protein,0.5951,6,0.9999883924124225,2407.9720489291135,37.0,0.9999860223190599,2407.966341744296,36.0,nonessential
1722,HNEAP_RS08965,WP_012824658.1,502586913.0,1936279,1938540,2261.0,-,mechanosensitive ion channel MscS,0.5698,43,0.8532729835328543,2054.6813443471133,99.0,0.8726854725357,2101.4266178659655,97.0,nonessential
1723,HNEAP_RS08970,WP_012824659.1,502586914.0,1938549,1940522,1973.0,-,excinuclease ABC subunit UvrC,0.5861,31,0.7982424179204659,1922.1677423524818,85.0,0.8126154106199021,1956.7779087727242,83.0,nonessential
1724,HNEAP_RS08975,WP_012824660.1,502586915.0,1940519,1941157,638.0,-,DNA-binding response regulator,0.5524,14,0.9231315180397501,2222.900695439718,32.0,0.9440063456059452,2273.167280219116,32.0,nonessential
1725,HNEAP_RS08980,WP_012824661.1,502586916.0,1941253,1941732,479.0,-,CYTH domain-containing protein,0.5292,6,0.016560959261284206,39.87878990117237,10.0,0.010913862079022662,26.28057988628657,9.0,nonessential
1726,HNEAP_RS08985,WP_012824662.1,502586917.0,1941753,1942724,971.0,-,ketoacyl-ACP synthase III,0.5669,21,0.9973709816932074,2401.669323917243,56.0,0.9991603251955562,2405.978063070899,57.0,nonessential
1727,HNEAP_RS08990,WP_012824663.1,502586918.0,1942721,1943743,1022.0,-,phosphate acetyltransferase PlsX,0.5787,22,9.901539664519596e-16,2.3842907512163188e-12,2.0,3.310830603665866e-15,7.972480093627405e-12,2.0,essential
1728,HNEAP_RS08995,WP_012824664.1,502586919.0,1943926,1944114,188.0,-,50S ribosomal protein L32,0.5344,2,0.004329789972398861,10.426134253536457,1.0,0.005316844259496146,12.80296097686672,1.0,nonessential
1729,HNEAP_RS09000,WP_012824665.1,502586920.0,1944207,1944845,638.0,-,hypothetical protein,0.5634,5,0.526877747285944,1268.7216154645532,25.0,0.2708110718769398,652.1130610796711,21.0,nonessential
1730,HNEAP_RS09005,WP_041600417.1,753844800.0,1944997,1945584,587.0,+,septum formation protein Maf,0.5867,10,1.5126644431014405e-08,3.642495978988269e-05,2.0,2.9503373621456006e-08,7.104412368046606e-05,2.0,essential
1731,HNEAP_RS09010,WP_012824667.1,502586922.0,1945592,1946812,1220.0,-,lysophospholipid transporter LplT,0.5774,28,0.9999354411090491,2407.8445421905903,76.0,0.9999756322200717,2407.941322385933,76.0,nonessential
1732,HNEAP_RS09015,WP_012824668.1,502586923.0,1947269,1947847,578.0,-,hypothetical protein,0.5475,7,0.3910056392115616,941.5415792214404,21.0,0.44850233327424666,1079.993618524386,21.0,nonessential
1733,HNEAP_RS09020,WP_012824669.1,502586924.0,1948042,1948752,710.0,+,DNA-binding response regulator,0.5738,5,0.9999998648551583,2407.9996745712215,58.0,0.9999998879756163,2407.9997302452844,57.0,nonessential
1734,HNEAP_RS09025,WP_049772516.1,908628483.0,1948749,1950239,1490.0,+,ATP-binding protein,0.5902,22,0.9995268365718223,2406.860622464948,85.0,0.9995536970118631,2406.9253024045665,83.0,nonessential
1735,HNEAP_RS09030,WP_012824671.1,502586926.0,1950351,1951580,1229.0,+,divalent metal cation transporter,0.5602,24,0.9999999239073004,2407.9998167687795,88.0,0.9999896645916811,2407.9751123367682,78.0,nonessential
1736,HNEAP_RS12330,WP_012824672.1,502586927.0,1951584,1954052,2468.0,-,GAF sensor-containing diguanylate cyclase/phosphodiesterase,0.4723,87,0.13991695618617603,336.9200304963119,87.0,0.11275511585894023,271.51431898832806,83.0,nonessential
1737,HNEAP_RS09040,WP_012824673.1,502586929.0,1954065,1954958,893.0,-,lipoprotein,0.4765,24,0.7609346056759116,1832.3305304675953,39.0,0.8560844245022057,2061.451294201311,40.0,nonessential
1738,HNEAP_RS09045,WP_012824674.1,502586930.0,1955008,1955529,521.0,-,hypothetical protein,0.4962,8,0.11946788024003288,287.6786556179992,15.0,0.09822876224470442,236.53485948524823,14.0,nonessential
1739,HNEAP_RS09050,WP_081441139.1,1174219958.0,1955715,1956641,926.0,-,hypothetical protein,0.521,20,0.9455263593615627,2276.827473342643,46.0,0.9071575524077228,2184.4353861977966,43.0,nonessential
1740,HNEAP_RS09055,WP_012824676.1,502586932.0,1956706,1957419,713.0,+,hypothetical protein,0.5546,12,0.06184118374482561,148.91357045754006,20.0,0.0031755091034408236,7.646625921085503,14.0,nonessential
1741,HNEAP_RS09060,WP_012824677.1,502586933.0,1957422,1959032,1610.0,-,peptide chain release factor 3,0.5717,29,0.9979902985080106,2403.1606388072896,87.0,0.9962195213505343,2398.8966074120867,83.0,nonessential
1742,HNEAP_RS09065,WP_041600418.1,753844801.0,1959124,1959318,194.0,+,hypothetical protein,0.5179,6,0.9889230333003972,2381.3266641873565,14.0,0.9914464683203068,2387.4030957152986,14.0,nonessential
1743,HNEAP_RS09070,WP_012824678.1,502586934.0,1959423,1960457,1034.0,+,folate-binding protein,0.543,25,0.9999999999964703,2407.9999999915003,90.0,0.9999999994051006,2407.999998567482,82.0,nonessential
1744,HNEAP_RS09075,WP_012824679.1,502586935.0,1960622,1961413,791.0,+,thiazole synthase,0.5682,15,1.2245505641921075e-14,2.9487177585745945e-11,0.0,3.27011129713467e-14,7.874428003500285e-11,0.0,essential
1745,HNEAP_RS09080,WP_012824680.1,502586936.0,1961397,1962161,764.0,+,tRNA (guanosine(46)-N7)-methyltransferase TrmB,0.5817,11,0.37747950569572697,908.9706497153105,28.0,0.44320592406372,1067.2398651454378,28.0,nonessential
1746,HNEAP_RS09085,WP_012824681.1,502586937.0,1962158,1962430,272.0,+,hypothetical protein,0.4872,7,0.7135309300308129,1718.1824795141974,12.0,0.7481058960346068,1801.438997651333,12.0,nonessential
1747,HNEAP_RS09090,WP_012824682.1,502586938.0,1962602,1963315,713.0,-,DNA polymerase III subunit epsilon,0.5784,11,1.3377434767211741e-10,3.2212862919445874e-07,2.0,3.0496533230763447e-10,7.343565201967838e-07,2.0,essential
1748,HNEAP_RS09095,WP_012824684.1,502586940.0,1963667,1964158,491.0,-,ribonuclease HI,0.5935,7,3.7275803424815214e-06,0.008976013464695504,3.0,6.266157320992072e-06,0.015088906828948909,3.0,essential
1749,HNEAP_RS09100,WP_012824685.1,502586941.0,1964160,1965005,845.0,-,type 11 methyltransferase,0.5934,10,0.7618777338298159,1834.6015830621968,37.0,0.8147078945532844,1961.8166100843089,37.0,nonessential
1750,HNEAP_RS09105,WP_049772517.1,908628484.0,1965088,1966290,1202.0,-,MFS transporter,0.5586,25,0.3242561505021686,780.808810409222,44.0,0.29130765264075015,701.4688275589264,42.0,nonessential
1751,HNEAP_RS09110,WP_012824687.1,502586943.0,1966343,1966957,614.0,-,DUF1294 domain-containing protein,0.4813,21,0.04547810257896711,109.5112710101528,16.0,0.037316608312829985,89.8583928172946,15.0,nonessential
1752,HNEAP_RS09115,WP_012824688.1,502586944.0,1966984,1968081,1097.0,-,chorismate synthase,0.602,16,5.4543651594783704e-17,1.3134111304023917e-13,2.0,2.0016151076774076e-16,4.819889179287197e-13,2.0,essential
1753,HNEAP_RS09120,WP_012824689.1,502586945.0,1968202,1969791,1589.0,+,AMP-dependent synthetase and ligase,0.5994,24,0.991954231936858,2388.6257905039542,82.0,0.9894782069793058,2382.6635224061683,79.0,nonessential
1754,HNEAP_RS09125,WP_012824690.1,502586946.0,1969788,1971080,1292.0,+,Orn/DAP/Arg decarboxylase 2,0.5777,23,0.924360858890294,2225.8609482078277,61.0,0.8953804458074016,2156.076113504223,58.0,nonessential
1755,HNEAP_RS09130,WP_012824691.1,502586947.0,1971141,1971743,602.0,-,methionine biosynthesis protein MetW,0.5755,7,6.68423977790969e-10,1.6095649385206532e-06,1.0,1.3691621192879102e-09,3.296942383245288e-06,1.0,essential
1756,HNEAP_RS09135,WP_012824692.1,502586948.0,1971740,1972951,1211.0,-,homoserine O-acetyltransferase,0.5743,29,5.024139717088591e-22,1.2098128438749327e-18,0.0,2.260233252601935e-21,5.442641672265459e-18,0.0,essential
1757,HNEAP_RS09140,WP_012824693.1,502586949.0,1973004,1973555,551.0,-,YggT family protein,0.5181,7,0.5677650695594137,1367.1782874990683,22.0,0.6242341846632253,1503.1559166690465,22.0,nonessential
1758,HNEAP_RS09145,WP_012824694.1,502586950.0,1973552,1974400,848.0,-,pyrroline-5-carboxylate reductase,0.5889,17,4.388682216058375e-14,1.0567946776268568e-10,1.0,2.1308535563756234e-12,5.131095363752501e-09,2.0,essential
1759,HNEAP_RS09150,WP_012824695.1,502586951.0,1974685,1975356,671.0,-,YggS family pyridoxal phosphate-dependent enzyme,0.5387,13,0.9999946922508508,2407.987218940049,51.0,0.9999792443384217,2407.9500203669195,48.0,nonessential
1760,HNEAP_RS09155,WP_012824696.1,502586952.0,1975671,1976720,1049.0,+,type IV pili twitching motility protein PilT,0.5362,19,0.9999560178171787,2407.8940909037665,68.0,0.999544720552916,2406.9036870914215,62.0,nonessential
1761,HNEAP_RS09160,WP_012824697.1,502586953.0,1976774,1977919,1145.0,+,twitching motility protein PilT,0.5384,10,0.020847244995283645,50.20016594864302,32.0,0.009321172812291226,22.445384131997272,29.0,nonessential
1762,HNEAP_RS09165,WP_012824698.1,502586954.0,1978022,1979185,1163.0,+,twitching motility protein PilT,0.5481,19,0.8303049800180501,1999.3743918834646,52.0,0.8791201269981813,2116.9212658116207,52.0,nonessential
1763,HNEAP_RS09170,WP_012824699.1,502586955.0,1980058,1980408,350.0,+,cytochrome C class I,0.5641,4,0.8392892588888713,2021.008535404402,17.0,0.8669301012616901,2087.5676838381496,17.0,nonessential
1764,HNEAP_RS09175,WP_041600419.1,753844802.0,1980426,1981775,1349.0,+,pyridine nucleotide-disulfide oxidoreductase,0.5274,37,0.29161671469808453,702.2130489929875,49.0,0.22372626294214104,538.7328411646756,46.0,nonessential
1765,HNEAP_RS09185,WP_012824702.1,502586958.0,1983391,1984620,1229.0,+,hypothetical protein,0.561,32,0.9997819814424673,2407.4750113134614,74.0,0.9999116333244158,2407.7872130451933,74.0,nonessential
1766,HNEAP_RS09190,WP_012824703.1,502586959.0,1984686,1985402,716.0,+,cytochrome c4,0.5579,12,0.9999962259061693,2407.990911982056,54.0,0.9999992760061378,2407.99825662278,55.0,nonessential
1767,HNEAP_RS09195,WP_012824705.1,502586961.0,1985867,1986148,281.0,-,Fe(2+)-trafficking protein,0.5426,6,0.21330162343566178,513.6303092330736,8.0,0.35666620654508924,858.8522253605748,9.0,nonessential
1768,HNEAP_RS09200,WP_012824706.1,502586962.0,1986171,1987316,1145.0,-,A/G-specific adenine glycosylase,0.582,22,0.9998792484674515,2407.7092303096233,71.0,0.9999169135226327,2407.7999277624995,70.0,nonessential
1769,HNEAP_RS12335,WP_012824707.1,502586963.0,1987350,1989743,2393.0,-,AsmA family protein,0.5405,42,0.9999999999464337,2407.9999998710123,162.0,0.9999999998881736,2407.999999730722,157.0,nonessential
1770,HNEAP_RS09210,WP_012824708.1,502586964.0,1989959,1990186,227.0,+,MoaD/ThiS family protein,0.5219,6,0.8060651822496382,1941.0049588571287,11.0,0.3511719226337994,845.621989702189,7.0,nonessential
1771,HNEAP_RS09215,WP_012824709.1,502586965.0,1990197,1990526,329.0,+,hypothetical protein,0.5364,8,0.9999999998508058,2407.9999996407405,40.0,0.9999999999836053,2407.9999999605216,41.0,nonessential
1772,HNEAP_RS09220,WP_012824710.1,502586966.0,1990651,1990962,311.0,+,glycoside hydrolase,0.4936,6,0.7433680435020351,1790.0302487529007,14.0,0.8507291826589731,2048.5558718428074,15.0,nonessential
1773,HNEAP_RS09225,WP_012824711.1,502586967.0,1991023,1991916,893.0,+,D-hexose-6-phosphate mutarotase,0.5403,17,0.11445860289896746,275.61631578071365,28.0,0.08110894313202392,195.3103350619136,26.0,nonessential
1774,HNEAP_RS09230,WP_012824712.1,502586968.0,1991957,1992658,701.0,-,type IV pilus assembly PilZ,0.5071,14,0.4870490297590422,1172.8140636597736,27.0,0.47404975642957214,1141.5118134824097,26.0,nonessential
1775,HNEAP_RS09235,WP_012824713.1,502586969.0,1992768,1994024,1256.0,-,6-phosphofructokinase,0.5823,27,0.9999998971746074,2407.9997523964544,89.0,0.9999999471107911,2407.999872642785,88.0,nonessential
1776,HNEAP_RS09240,WP_012824714.1,502586970.0,1994121,1995125,1004.0,+,class 1 fructose-bisphosphatase,0.5413,20,2.1966230516063104e-18,5.289468308267996e-15,0.0,7.642089444558284e-18,1.8402151382496347e-14,0.0,essential
1777,HNEAP_RS09245,WP_012824715.1,502586971.0,1995229,1995804,575.0,-,sterol-binding protein,0.5642,7,0.8416112245363709,2026.599828683581,27.0,0.8757704229767602,2108.855178528039,27.0,nonessential
1778,HNEAP_RS09250,WP_012824716.1,502586972.0,1995993,1996439,446.0,-,hypothetical protein,0.5391,6,0.9874087554550764,2377.680283135824,27.0,0.9745507092411799,2346.7181078527615,25.0,nonessential
1779,HNEAP_RS09255,WP_012824717.1,502586973.0,1996505,1999207,2702.0,-,GNAT family N-acetyltransferase,0.5882,43,0.9998860770276919,2407.7256734826824,146.0,0.9995194873118735,2406.842925446991,138.0,nonessential
1780,HNEAP_RS09260,WP_012824718.1,502586974.0,1999475,2000407,932.0,+,deacetylase,0.5809,15,0.9999579041601026,2407.898633217527,62.0,0.9999678327259541,2407.9225412040973,61.0,nonessential
1781,HNEAP_RS09265,WP_012824719.1,502586975.0,2000540,2001340,800.0,+,undecaprenyl-diphosphate phosphatase,0.5343,21,8.505222642936686e-15,2.048057612419154e-11,0.0,2.2968106454231062e-14,5.53072003417884e-11,0.0,essential
1782,HNEAP_RS09270,WP_041600977.1,753845360.0,2001408,2001911,503.0,-,transcription antitermination factor NusB,0.5913,6,1.4232784559346747e-09,3.4272545218906965e-06,0.0,2.6580152279515992e-09,6.400500668907451e-06,0.0,essential
1783,HNEAP_RS09275,WP_012824721.1,502586977.0,2001995,2002486,491.0,-,6 7-dimethyl-8-ribityllumazine synthase,0.5589,11,2.313900022043526e-09,5.57187125308081e-06,0.0,4.257362072345219e-09,1.0251727870207287e-05,0.0,essential
1784,HNEAP_RS09280,WP_012824722.1,502586978.0,2002511,2003644,1133.0,-,bifunctional 3 4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II,0.5653,17,5.656886580299807e-19,1.3621782885361933e-15,1.0,2.239236605649488e-18,5.392081746403968e-15,1.0,essential
1785,HNEAP_RS09285,WP_012824723.1,502586979.0,2003738,2004388,650.0,-,riboflavin synthase,0.5469,12,5.172624042715967e-07,0.0012455678694860048,5.0,9.958523225937806e-07,0.0023980123928058236,5.0,essential
1786,HNEAP_RS09290,WP_012824724.1,502586980.0,2004478,2005638,1160.0,-,riboflavin biosynthesis protein RibD,0.6098,17,4.744493354451838e-18,1.1424739997520025e-14,2.0,1.8826453414290014e-17,4.5334099821610353e-14,2.0,essential
1787,HNEAP_RS09295,WP_012824725.1,502586981.0,2005628,2006155,527.0,-,transcriptional regulator NrdR,0.5549,11,0.1620792120254024,390.28674255716896,16.0,0.08988531616136713,216.44384131657205,14.0,nonessential
1788,HNEAP_RS09300,WP_012824726.1,502586982.0,2006177,2007430,1253.0,-,serine hydroxymethyltransferase,0.5646,26,4.840396561472701e-21,1.1655674920026265e-17,1.0,2.2237802133059706e-20,5.354862753640777e-17,1.0,essential
1789,HNEAP_RS09305,WP_012824727.1,502586983.0,2007470,2007709,239.0,+,hypothetical protein,0.3958,9,0.5224287318214611,1258.0083862260783,9.0,0.5605209370540147,1349.7344164260676,9.0,nonessential
1790,HNEAP_RS09310,WP_012824728.1,502586984.0,2007744,2008232,488.0,+,Crp/Fnr family transcriptional regulator,0.501,15,0.25948067740790876,624.8294711982443,16.0,0.2239942175762651,539.3780759236463,15.0,nonessential
1791,HNEAP_RS09315,WP_012824729.1,502586985.0,2008264,2010723,2459.0,-,copper-translocating P-type ATPase,0.55,47,5.789426389467837e-42,1.3940938745838553e-38,1.0,1.1888103851247928e-40,2.862655407380501e-37,1.0,essential
1792,HNEAP_RS09320,WP_012824730.1,502586986.0,2010764,2011567,803.0,-,nitrogen fixation protein FixH,0.5211,18,0.00010480000583061237,0.2523584140401146,13.0,0.00019148876983326603,0.4611049577585046,13.0,nonessential
1793,HNEAP_RS09325,WP_012824731.1,502586987.0,2011816,2013237,1421.0,-,cytochrome c oxidase accessory protein CcoG,0.4873,44,0.21358077993156935,514.302518075219,50.0,0.0763150493699381,183.76663888281095,44.0,nonessential
1794,HNEAP_RS09330,WP_012824732.1,502586988.0,2013559,2014536,977.0,-,cytochrome c oxidase subunit III,0.5,31,6.555844515620066e-18,1.578647359361312e-14,0.0,2.2055867353508184e-17,5.311052858724771e-14,0.0,essential
1795,HNEAP_RS09335,WP_081441191.1,1174220010.0,2014514,2014723,209.0,-,cbb3-type cytochrome c oxidase subunit 3,0.4429,12,0.00021092613058815816,0.5079101224562849,0.0,0.0002734286111470168,0.6584160956420165,0.0,ambiguous
1796,HNEAP_RS09340,WP_012824734.1,502586990.0,2014790,2015521,731.0,-,cytochrome-c oxidase  cbb3-type subunit II,0.5027,21,1.3907539312387705e-13,3.3489354664229596e-10,0.0,3.447292579688003e-13,8.301080531888712e-10,0.0,essential
1797,HNEAP_RS09345,WP_012824735.1,502586992.0,2015536,2016996,1460.0,-,cytochrome-c oxidase  cbb3-type subunit I,0.5284,54,1.286532653609585e-24,3.0979706298918807e-21,1.0,7.642398606422478e-24,1.840289584426533e-20,1.0,essential
1798,HNEAP_RS09350,WP_012824736.1,502586993.0,2017281,2018081,800.0,-,malonyl-[acyl-carrier protein] O-methyltransferase BioC,0.5493,19,2.897139522421282e-13,6.976311969990446e-10,1.0,7.586187278698394e-13,1.8267538967105733e-09,1.0,essential
1799,HNEAP_RS09355,WP_012824737.1,502586994.0,2018074,2018826,752.0,-,hypothetical protein,0.5485,13,5.8684264790683865e-06,0.014131170961596674,9.0,1.8992376548322652e-07,0.00045733642728360945,6.0,essential
1800,HNEAP_RS09360,WP_012824738.1,502586995.0,2018942,2019577,635.0,+,acyl-phosphate glycerol 3-phosphate acyltransferase,0.577,20,6.78715885118567e-12,1.6343478513655092e-08,0.0,1.4932864400666113e-11,3.5958337476804e-08,0.0,essential
1801,HNEAP_RS09365,WP_012824739.1,502586996.0,2019590,2020603,1013.0,-,tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD,0.5937,15,1.4011671258614548e-15,3.374010439074383e-12,2.0,2.230586201711816e-16,5.371251573722053e-13,1.0,essential
1802,HNEAP_RS09370,WP_012824740.1,502586997.0,2020706,2022049,1343.0,-,TlpA family protein disulfide reductase,0.5491,23,0.9997104609703866,2407.302790016691,79.0,0.9998145822667079,2407.553514098233,78.0,nonessential
1803,HNEAP_RS09375,WP_041600984.1,753845367.0,2022269,2023180,911.0,+,phosphoribosylaminoimidazolesuccinocarboxamide synthase,0.5669,13,6.801042711225035e-11,1.6376910848629883e-07,5.0,2.413367137876695e-11,5.811388068007082e-08,4.0,essential
1804,HNEAP_RS09380,WP_012824742.1,502586999.0,2023216,2023980,764.0,+,dethiobiotin synthase,0.5608,20,1.1444468140989125e-06,0.002755827928350181,8.0,5.863372803906382e-07,0.0014119001711806567,7.0,essential
1805,HNEAP_RS09385,WP_012824743.1,502587000.0,2024012,2024446,434.0,-,nuclear transport factor 2 family protein,0.5609,11,0.853072441080126,2054.1984381209436,21.0,0.7633001966177613,1838.026873455569,19.0,nonessential
1806,HNEAP_RS09390,WP_012824744.1,502587001.0,2024443,2025213,770.0,-,oxidoreductase,0.5357,12,0.7131461775624868,1717.2559955704683,33.0,0.7693688039402866,1852.6400798882103,33.0,nonessential
1807,HNEAP_RS09395,WP_012824745.1,502587002.0,2025418,2026719,1301.0,+,NAD/FAD-binding protein,0.5031,30,0.3345010757113015,805.478590312814,48.0,0.4180641753492666,1006.6985342410339,48.0,nonessential
1808,HNEAP_RS09400,WP_012824746.1,502587003.0,2026716,2027510,794.0,+,DUF1365 domain-containing protein,0.5019,18,0.7131634672513354,1717.2976291412156,34.0,0.7127225420440246,1716.2358812420114,33.0,nonessential
1809,HNEAP_RS09405,WP_012824747.1,502587004.0,2027492,2028766,1274.0,+,class I SAM-dependent methyltransferase,0.5349,30,0.8404680847079586,2023.8471479767645,57.0,0.860581187718978,2072.279500027299,56.0,nonessential
1810,HNEAP_RS09410,WP_012824748.1,502587005.0,2028763,2030085,1322.0,+,MFS transporter,0.5616,29,0.9948565794234264,2395.6146432516107,71.0,0.9962563736123875,2398.985347658629,70.0,nonessential
1811,HNEAP_RS09415,WP_012824749.1,502587006.0,2030082,2030618,536.0,+,DUF3833 domain-containing protein,0.4786,18,0.010037520845046609,24.170350194872235,11.0,0.014125616947537202,34.014485609669585,11.0,nonessential
1812,HNEAP_RS09420,WP_012824750.1,502587007.0,2030620,2031216,596.0,+,hypothetical protein,0.5193,15,0.7935133474491269,1910.7801406574977,27.0,0.7798424331316733,1877.8605789810695,26.0,nonessential
1813,HNEAP_RS09425,WP_012824751.1,502587008.0,2031217,2031456,239.0,-,DUF2789 domain-containing protein,0.5333,4,0.6484269668653111,1561.4121362116691,10.0,0.5605209370540147,1349.7344164260676,9.0,nonessential
1814,HNEAP_RS09430,WP_012824752.1,502587009.0,2031493,2032536,1043.0,-,protease SohB,0.5268,19,0.0011249733534437834,2.7089358350926305,23.0,0.0002761332626075984,0.6649288963590969,20.0,nonessential
1815,HNEAP_RS09435,WP_041600990.1,753845373.0,2032915,2033766,851.0,+,Tim44 domain-containing protein,0.5845,7,0.0018893886216168236,4.549647800853311,18.0,0.0031596627454155268,7.608467890960588,18.0,nonessential
1816,HNEAP_RS09440,WP_012824754.1,502587011.0,2033835,2034626,791.0,-,CDP-diacylglycerol--serine O-phosphatidyltransferase,0.5404,17,1.2245505641921075e-14,2.9487177585745945e-11,0.0,3.27011129713467e-14,7.874428003500285e-11,0.0,essential
1817,HNEAP_RS09445,WP_012824755.1,502587012.0,2034806,2035822,1016.0,-,ketol-acid reductoisomerase,0.5526,21,1.3511414647896715e-18,3.253548647213529e-15,0.0,4.771215079156881e-18,1.148908591060977e-14,0.0,essential
1818,HNEAP_RS09450,WP_012824756.1,502587013.0,2035873,2036373,500.0,-,acetolactate synthase small subunit,0.5429,9,3.772702497853648e-07,0.0009084667614831585,2.0,6.607879374256835e-07,0.0015911773533210459,2.0,essential
1819,HNEAP_RS09455,WP_012824757.1,502587014.0,2036377,2038077,1700.0,-,acetolactate synthase 3 large subunit,0.552,39,1.2606138789667883e-30,3.035558220552026e-27,0.0,1.0408569198290953e-29,2.5063834629484616e-26,0.0,essential
1820,HNEAP_RS09460,WP_012824758.1,502587015.0,2038388,2039323,935.0,-,hypothetical protein,0.5128,28,0.9981396185298574,2403.5202014198967,55.0,0.9984378297774649,2404.2382941041355,54.0,nonessential
1821,HNEAP_RS12340,WP_012824759.1,502587016.0,2039394,2039771,377.0,-,hypothetical protein,0.5503,6,0.9830808699445095,2367.2587348263787,23.0,0.9878365554491235,2378.7104255214895,23.0,nonessential
1822,HNEAP_RS09470,WP_012824760.1,502587017.0,2039762,2039992,230.0,-,SirA family protein,0.5887,2,0.9576094089630445,2305.9234567830113,14.0,0.9660370762806884,2326.2172796838977,14.0,nonessential
1823,HNEAP_RS09475,WP_012824761.1,502587018.0,2039996,2040313,317.0,-,rhodanese,0.544,4,0.9998028416142452,2407.5252426071024,26.0,0.9997112891689823,2407.3047843189092,25.0,nonessential
1824,HNEAP_RS09480,WP_041600420.1,753844803.0,2040833,2041075,242.0,-,hypothetical protein,0.3333,16,0.03503972358724124,84.3756543980769,4.0,0.09340935166390504,224.92971880668335,5.0,nonessential
1825,HNEAP_RS09485,WP_041600421.1,753844804.0,2041107,2041493,386.0,+,sulfur oxidation c-type cytochrome SoxX,0.4935,9,0.3290098005137991,792.2555996372282,13.0,0.27465277212194844,661.3638752696519,12.0,nonessential
1826,HNEAP_RS09490,WP_012824763.1,502587020.0,2041537,2042442,905.0,+,sulfur oxidation c-type cytochrome SoxA,0.4779,32,0.8298957458166781,1998.388955926561,41.0,0.836538153079206,2014.383872614728,40.0,nonessential
1827,HNEAP_RS09495,WP_012824764.1,502587021.0,2042496,2043248,752.0,-,DedA family protein,0.498,20,0.021279322355950387,51.24060823312853,19.0,0.030822160249741732,74.21976188137809,19.0,nonessential
1828,HNEAP_RS12345,WP_012824765.1,502587022.0,2043235,2045103,1868.0,-,family 2 glycosyl transferase,0.5436,41,0.00014304575868040638,0.3444541869024186,45.0,0.00012665914776573944,0.30499522781990057,43.0,nonessential
1829,HNEAP_RS09505,WP_012824766.1,502587023.0,2045107,2045625,518.0,-,molybdenum cofactor biosynthesis protein B,0.5568,11,0.1817302486275232,437.6064386950759,16.0,0.10263258339359323,247.1392608117725,14.0,nonessential
1830,HNEAP_RS09510,WP_012824767.1,502587024.0,2045651,2045890,239.0,-,DUF3565 domain-containing protein,0.55,4,0.38987758153260815,938.8252163305204,8.0,0.5605209370540147,1349.7344164260676,9.0,nonessential
1831,HNEAP_RS09515,WP_012824768.1,502587025.0,2045919,2047283,1364.0,-,30S ribosomal protein S12 methylthiotransferase RimO,0.5707,31,0.5286376125391536,1272.959370994282,54.0,0.45205545129515146,1088.5495267187248,51.0,nonessential
1832,HNEAP_RS09520,WP_012824769.1,502587026.0,2047314,2047640,326.0,-,DUF3579 domain-containing protein,0.5015,5,1.8464898186308824e-06,0.0044463474832631645,0.0,2.76795175333919e-06,0.006665227822040769,0.0,essential
1833,HNEAP_RS09525,WP_012824770.1,502587027.0,2047873,2048406,533.0,+,asparaginase,0.5131,11,0.9983659231139947,2404.0651428584993,35.0,0.9900932643461072,2384.1445805454264,31.0,nonessential
1834,HNEAP_RS09530,WP_012824771.1,502587028.0,2048489,2050291,1802.0,-,thiosulfohydrolase SoxB,0.523,45,2.0258953579580072e-32,4.878356021962881e-29,0.0,1.8986044561825863e-31,4.571839530487668e-28,0.0,essential
1835,HNEAP_RS12350,WP_081441140.1,1174219959.0,2050602,2051768,1166.0,-,hypothetical protein,0.5913,20,7.430074375012972e-15,1.7891619095031236e-11,5.0,2.7063557864603146e-14,6.516904733796438e-11,5.0,essential
1836,HNEAP_RS09540,WP_012824773.1,502587030.0,2051680,2052333,653.0,-,dTMP kinase,0.5963,3,9.163757090966485e-11,2.2066327075047296e-07,1.0,1.999585356022249e-10,4.815001537301575e-07,1.0,essential
1837,HNEAP_RS09545,WP_081441141.1,1174219960.0,2052356,2053483,1127.0,-,hypothetical protein,0.5691,25,0.9999247228621022,2407.818732651942,71.0,0.999948438697642,2407.875840383922,70.0,nonessential
1838,HNEAP_RS09550,WP_081441142.1,1174219961.0,2053422,2054414,992.0,-,hypothetical protein,0.5932,17,0.9999959137537613,2407.9901603190574,69.0,0.9999667271403281,2407.91987895391,64.0,nonessential
1839,HNEAP_RS09555,WP_012824776.1,502587033.0,2054336,2055799,1463.0,-,anthranilate synthase,0.5833,21,0.9834720801713689,2368.200769052656,74.0,0.8920600083238092,2148.0805000437326,65.0,nonessential
1840,HNEAP_RS09560,WP_012824777.1,502587034.0,2055827,2057068,1241.0,-,beta-ketoacyl-[acyl-carrier-protein] synthase II,0.5837,23,4.837106260214092e-16,1.1647751874595534e-12,5.0,3.5283995836236783e-20,8.496386197365817e-17,1.0,essential
1841,HNEAP_RS09565,WP_012824778.1,502587035.0,2057186,2057425,239.0,-,acyl carrier protein,0.4708,4,6.258836389135657e-05,0.15071278025038662,0.0,8.421435975138225e-05,0.20278817828132847,0.0,ambiguous
1842,HNEAP_RS09570,WP_012824779.1,502587036.0,2057602,2058354,752.0,-,3-oxoacyl-ACP reductase FabG,0.5923,13,5.941615522552241e-14,1.4307410178305798e-10,0.0,1.5116723896160237e-13,3.640107114195385e-10,0.0,essential
1843,HNEAP_RS09575,WP_012824780.1,502587037.0,2058406,2059326,920.0,-,[acyl-carrier-protein] S-malonyltransferase,0.6156,12,5.018527082167321e-14,1.208461321385891e-10,2.0,2.0667786721459954e-16,4.976803042527557e-13,0.0,essential
1844,HNEAP_RS09580,WP_041600422.1,753844805.0,2059516,2060691,1175.0,+,glycosyltransferase family 4 protein,0.5595,23,0.9999999999999999,2407.9999999999995,132.0,0.9999999999999999,2407.9999999999995,127.0,nonessential
1845,HNEAP_RS09585,WP_012824782.1,502587039.0,2060851,2062635,1784.0,+,RNA helicase,0.5927,21,0.9998571964991047,2407.656129169844,102.0,0.9975002092134908,2401.980503786086,92.0,nonessential
1846,HNEAP_RS09590,WP_012824783.1,502587040.0,2062803,2063378,575.0,+,methylated-DNA--[protein]-cysteine S-methyltransferase,0.5503,15,0.8851065908899555,2131.336670863013,28.0,0.912265358080809,2196.734982258588,28.0,nonessential
1847,HNEAP_RS09595,WP_041601002.1,753845385.0,2063490,2064668,1178.0,-,formate-dependent phosphoribosylglycinamide formyltransferase,0.6022,20,0.9999999999988423,2407.999999997212,100.0,0.9999999999974928,2407.999999993963,97.0,nonessential
1848,HNEAP_RS09600,WP_049772523.1,908628490.0,2064780,2065127,347.0,-,DUF3301 domain-containing protein,0.5172,6,0.8993108289024276,2165.5404759970456,18.0,0.9190798263433517,2213.144221834791,18.0,nonessential
1849,HNEAP_RS09605,WP_012824786.1,502587043.0,2065342,2065557,215.0,+,30S ribosomal protein S21,0.537,3,0.0016353488112131602,3.93791993740129,1.0,0.0020757678703539296,4.998449031812262,1.0,nonessential
1850,HNEAP_RS09610,WP_012824787.1,502587044.0,2065593,2066042,449.0,+,hypothetical protein,0.58,9,0.66890666264782,1610.7272436559504,19.0,0.7156732462068671,1723.341176866136,19.0,nonessential
1851,HNEAP_RS09615,WP_012824788.1,502587045.0,2066164,2067573,1409.0,+,glutamate synthase subunit beta,0.5652,26,1.6544700727006148e-25,3.9839639350630803e-22,0.0,9.51769415914002e-25,2.2918607535209166e-21,0.0,essential
1852,HNEAP_RS09620,WP_012824789.1,502587046.0,2067754,2068851,1097.0,+,uroporphyrinogen decarboxylase,0.5856,21,4.590146322908905e-12,1.1053072345564643e-08,7.0,1.4430959622223964e-11,3.4749750770315304e-08,7.0,essential
1853,HNEAP_RS09625,WP_012824790.1,502587047.0,2068885,2069487,602.0,-,hypothetical protein,0.5406,12,0.8328679777133722,2005.5460903338003,28.0,0.8690314721451957,2092.627784925631,28.0,nonessential
1854,HNEAP_RS09630,WP_012824791.1,502587048.0,2069506,2071878,2372.0,-,penicillin-binding protein 1A,0.5192,61,0.9934594431675456,2392.2503391474497,118.0,0.9937646688522271,2392.985322596163,115.0,nonessential
1855,HNEAP_RS09635,WP_012824792.1,502587049.0,2072022,2073119,1097.0,+,pilus assembly protein PilM,0.5046,29,0.9739395849023649,2345.2465204448945,56.0,0.9691659451375696,2333.7515958912677,54.0,nonessential
1856,HNEAP_RS09640,WP_012824793.1,502587050.0,2073116,2073706,590.0,+,fimbrial assembly family protein,0.467,15,0.06641925733701849,159.93757166754054,16.0,0.08684791844738639,209.12978762130643,16.0,nonessential
1857,HNEAP_RS09645,WP_012824794.1,502587051.0,2073710,2074324,614.0,+,pilus assembly protein PilO,0.4732,13,0.8551079005429387,2059.0998245073965,29.0,0.8881589445578614,2138.6867384953302,29.0,nonessential
1858,HNEAP_RS09650,WP_012824795.1,502587052.0,2074321,2074872,551.0,+,pilus assembly protein PilP,0.5036,12,0.17067551762216632,410.98664643417646,17.0,0.20864780563835336,502.4239159771549,17.0,nonessential
1859,HNEAP_RS09655,WP_012824796.1,502587054.0,2074892,2077081,2189.0,+,type IV pilus secretin PilQ,0.5041,55,0.010540393628934254,25.381267858473684,66.0,0.011609709688499508,27.956180929906818,64.0,nonessential
1860,HNEAP_RS09660,WP_012824797.1,502587055.0,2077153,2077656,503.0,+,shikimate kinase AroK,0.5179,16,3.101096337920098e-08,7.467439981711595e-05,1.0,5.6186121186015694e-08,0.0001352961798159258,1.0,essential
1861,HNEAP_RS09665,WP_012823370.1,502585589.0,2077867,2078904,1037.0,+,IS5/IS1182 family transposase,0.5645,14,5.772382101561005e-19,1.3899896100558902e-15,0.0,2.0922256911346512e-18,5.0380794642522404e-15,0.0,essential
1862,HNEAP_RS09670,WP_012824798.1,502587056.0,2079276,2080307,1031.0,-,RNA polymerase sigma factor RpoS,0.5048,17,0.667122947668121,1606.4320579848352,43.0,0.6825173847988016,1643.5018625955142,42.0,nonessential
1863,HNEAP_RS09675,WP_012824799.1,502587057.0,2080688,2081911,1223.0,+,hypothetical protein,0.5547,23,0.9999974172687937,2407.9937807832553,82.0,0.9999972689869403,2407.993423720552,80.0,nonessential
1864,HNEAP_RS09680,WP_012824800.1,502587058.0,2081916,2083031,1115.0,+,phosphoserine transaminase,0.5358,20,0.79203552667894,1907.2215482428874,49.0,0.809099263742407,1948.3110270917161,48.0,nonessential
1865,HNEAP_RS09685,WP_012824801.1,502587059.0,2083085,2083558,473.0,+,NUDIX hydrolase,0.519,11,0.008995292939434192,21.660665398157533,9.0,0.005530119212837097,13.31652706451173,8.0,nonessential
1866,HNEAP_RS09690,WP_012824802.1,502587060.0,2083555,2084688,1133.0,+,tRNA 2-thiouridine(34) synthase MnmA,0.5582,25,1.352165897332434e-17,3.256015480776501e-14,2.0,5.1887349792158466e-17,1.2494473829951757e-13,2.0,essential
1867,HNEAP_RS09695,WP_012824803.1,502587061.0,2084724,2085353,629.0,+,DUF489 domain-containing protein,0.5381,13,1.9147610580710627e-07,0.0004610744627835119,4.0,3.702329850260105e-07,0.0008915210279426333,4.0,essential
1868,HNEAP_RS09700,WP_012824804.1,502587062.0,2085404,2085727,323.0,-,DUF2818 domain-containing protein,0.5093,8,2.085021780312084e-06,0.0050207324469914985,0.0,3.1138973824808796e-06,0.007498264897013958,0.0,essential
1869,HNEAP_RS09705,WP_012824805.1,502587063.0,2085805,2087250,1445.0,-,NADH-quinone oxidoreductase subunit NuoN,0.5491,36,3.850301793565278e-26,9.27152671890519e-23,0.0,2.316233714270568e-25,5.577490783963528e-22,0.0,essential
1870,HNEAP_RS09710,WP_012824806.1,502587064.0,2087259,2088782,1523.0,-,NADH-quinone oxidoreductase subunit M,0.5459,33,1.635456985265991e-27,3.9381804205205066e-24,0.0,1.0839071597179861e-26,2.6100484406009105e-23,0.0,essential
1871,HNEAP_RS09715,WP_012824807.1,502587065.0,2088808,2090766,1958.0,-,NADH-quinone oxidoreductase subunit L,0.5411,43,3.655154325949316e-35,8.801611616885952e-32,0.0,4.157707265242395e-34,1.0011759094703687e-30,0.0,essential
1872,HNEAP_RS09720,WP_012824808.1,502587066.0,2090770,2091075,305.0,-,NADH-quinone oxidoreductase subunit NuoK,0.4902,7,5.8803149132782545e-05,0.14159798311174038,1.0,8.339102767618022e-05,0.20080559464424197,1.0,nonessential
1873,HNEAP_RS09725,WP_012824809.1,502587067.0,2091068,2091727,659.0,-,NADH:ubiquinone oxidoreductase subunit J,0.5318,10,2.567902821241334e-12,6.183509993549132e-09,0.0,5.820722261760298e-12,1.4016299206318799e-08,0.0,essential
1874,HNEAP_RS09730,WP_012824810.1,502587068.0,2091793,2092281,488.0,-,NADH-quinone oxidoreductase subunit NuoI,0.5276,13,2.6128126430735537e-09,6.291652844521117e-06,0.0,4.789457980023041e-09,1.1533014815895482e-05,0.0,essential
1875,HNEAP_RS09735,WP_012824811.1,502587069.0,2092353,2093411,1058.0,-,NADH-quinone oxidoreductase subunit NuoH,0.5326,23,2.46609226307837e-19,5.938350169492716e-16,0.0,9.174619609513388e-19,2.209248401970824e-15,0.0,essential
1876,HNEAP_RS09740,WP_081441192.1,1174220011.0,2093405,2095789,2384.0,-,NADH-quinone oxidoreductase subunit G,0.5711,40,1.1761517156096389e-42,2.8321733311880103e-39,0.0,2.2706650393709686e-41,5.467761414805292e-38,0.0,essential
1877,HNEAP_RS09745,WP_012824813.1,502587071.0,2095815,2097104,1289.0,-,NADH-quinone oxidoreductase subunit F,0.5636,24,1.1582139712549074e-21,2.7889792427818172e-18,1.0,1.4630330403393828e-19,3.5229835611372337e-16,2.0,essential
1878,HNEAP_RS09750,WP_012824814.1,502587072.0,2097109,2097606,497.0,-,NAD(P)H-dependent oxidoreductase subunit E,0.5181,14,1.8147517875900602e-09,4.369922304516865e-06,0.0,3.363946078521053e-09,8.100382157078694e-06,0.0,essential
1879,HNEAP_RS09755,WP_012824815.1,502587073.0,2097606,2098859,1253.0,-,NADH-quinone oxidoreductase subunit NuoD,0.5407,39,9.170018393940448e-23,2.2081404292608597e-19,0.0,4.346226270952414e-22,1.0465712860453413e-18,0.0,essential
1880,HNEAP_RS09760,WP_012824816.1,502587074.0,2098862,2099596,734.0,-,NADH-quinone oxidoreductase subunit C,0.551,14,6.04524383939457e-11,1.4556947165262124e-07,2.0,1.4144565939047782e-10,3.4060114781227055e-07,2.0,essential
1881,HNEAP_RS09765,WP_012824817.1,502587075.0,2099634,2100113,479.0,-,NADH dehydrogenase subunit B,0.5583,14,3.761831207159628e-09,9.058489546840384e-06,0.0,6.8190473946275016e-09,1.6420266126263024e-05,0.0,essential
1882,HNEAP_RS09770,WP_012824818.1,502587076.0,2100104,2100460,356.0,-,NADH-quinone oxidoreductase subunit A,0.493,9,5.479111401128739e-07,0.0013193700253918003,0.0,8.525124117491939e-07,0.002052849887492059,0.0,essential
1883,HNEAP_RS09780,WP_012824819.1,502587077.0,2100759,2101217,458.0,-,preprotein translocase subunit SecG,0.5272,9,0.00023256019635113794,0.5600049528135401,5.0,0.000353900754479033,0.8521930167855114,5.0,nonessential
1884,HNEAP_RS09785,WP_012824820.1,502587078.0,2101217,2101987,770.0,-,triose-phosphate isomerase,0.5707,14,2.8663054764931637e-14,6.902063587395538e-11,0.0,7.457323747395886e-14,1.7957235583729295e-10,0.0,essential
1885,HNEAP_RS09790,WP_012824821.1,502587079.0,2102114,2103454,1340.0,-,phosphoglucosamine mutase,0.5518,25,2.7053504115334932e-24,6.514483790972651e-21,0.0,7.806682519759897e-22,1.879849150758183e-18,1.0,essential
1886,HNEAP_RS09795,WP_012824822.1,502587080.0,2103619,2104335,716.0,-,cytochrome C class I,0.5467,13,0.998829381328245,2405.181150238414,45.0,0.9993647539582367,2406.4703275314337,45.0,nonessential
1887,HNEAP_RS09800,WP_012824823.1,502587081.0,2104505,2105362,857.0,-,dihydropteroate synthase,0.5688,13,6.923725182206606e-05,0.16672330238753508,14.0,5.191011526255458e-05,0.12499955755223144,13.0,nonessential
1888,HNEAP_RS09805,WP_081441193.1,1174220012.0,2105370,2107337,1967.0,-,ATP-dependent zinc metalloprotease FtsH,0.5711,22,2.3556594881595306e-30,5.67242804748815e-27,3.0,2.4663139889158236e-29,5.938884085309303e-26,3.0,essential
1889,HNEAP_RS09810,WP_012824825.1,502587083.0,2107398,2108027,629.0,-,23S rRNA (uridine(2552)-2'-O)-methyltransferase RlmE,0.554,14,0.9991019083167778,2405.837395226801,41.0,0.9951230567922699,2396.256320755786,37.0,nonessential
1890,HNEAP_RS09815,WP_012824826.1,502587084.0,2108159,2108602,443.0,-,copper chaperone PCu(A)C,0.5473,5,0.689998703558832,1661.5168781696673,19.0,0.7351262904517188,1770.184107407739,19.0,nonessential
1891,HNEAP_RS12355,WP_012824827.1,502587085.0,2108599,2109318,719.0,-,SCO family protein,0.5389,19,0.8295042049666679,1997.4461255597362,33.0,0.8691667865400295,2092.953621988391,33.0,nonessential
1892,HNEAP_RS09825,WP_012824828.1,502587086.0,2109535,2109855,320.0,+,ribosome assembly RNA-binding protein YhbY,0.5545,8,0.9999999999369448,2407.999999848163,40.0,0.999999999906864,2407.999999775728,39.0,nonessential
1893,HNEAP_RS09830,WP_012824829.1,502587087.0,2109874,2110557,683.0,+,leucyl/phenylalanyl-tRNA--protein transferase,0.5702,14,0.9999999989525246,2407.9999974776792,62.0,0.9999999998755994,2407.9999997004434,63.0,nonessential
1894,HNEAP_RS09835,WP_012824830.1,502587088.0,2110623,2112623,2000.0,+,sodium/hydrogen exchanger,0.5887,23,3.994837549839538e-17,9.619568820013607e-14,18.0,1.2817777277492868e-17,3.086520768420283e-14,16.0,essential
1895,HNEAP_RS09840,WP_012824831.1,502587089.0,2112753,2112986,233.0,+,hypothetical protein,0.5983,2,0.9753422965429862,2348.6242500755106,15.0,0.9626143580387678,2317.975374157353,14.0,nonessential
1896,HNEAP_RS09845,WP_012824832.1,502587090.0,2113162,2116641,3479.0,+,transcription-repair coupling factor,0.5954,55,0.9997969221151272,2407.510988453226,180.0,0.9996005775465368,2407.0381907320607,173.0,nonessential
1897,HNEAP_RS09850,WP_012824833.1,502587091.0,2116638,2117108,470.0,+,RDD family protein,0.5648,10,0.9417105487071289,2267.6390012867664,25.0,0.7967232578904585,1918.5096050002242,21.0,nonessential
1898,HNEAP_RS09855,WP_081441143.1,1174219962.0,2117275,2119425,2150.0,-,exodeoxyribonuclease V subunit alpha,0.5867,28,0.9972912267177739,2401.4772739364,111.0,0.9962184549338551,2398.894039480723,107.0,nonessential
1899,HNEAP_RS09860,WP_049772525.1,908628492.0,2119416,2123174,3758.0,-,exodeoxyribonuclease V subunit beta,0.5693,56,0.2922873386626915,703.8279114997612,142.0,0.33455511431005014,805.6087152586007,139.0,nonessential
1900,HNEAP_RS09865,WP_012824836.1,502587094.0,2123198,2123590,392.0,-,type II toxin-antitoxin system death-on-curing family toxin,0.5394,11,0.846308618017084,2037.9111521851382,19.0,0.8171841111533897,1967.7793396573625,18.0,nonessential
1901,HNEAP_RS09870,WP_012824837.1,502587095.0,2123587,2123811,224.0,-,transcriptional regulator,0.48,6,0.00011489787385085696,0.27667408023286355,0.0,0.00015174523196942856,0.365402518582384,0.0,ambiguous
1902,HNEAP_RS09875,WP_012824838.1,502587096.0,2124017,2125120,1103.0,-,porin,0.4955,44,3.9861546190835735e-20,9.598660322753245e-17,0.0,1.5681996731791225e-19,3.776224813015327e-16,0.0,essential
1903,HNEAP_RS09880,WP_012824840.1,502587098.0,2125632,2126990,1358.0,-,hypothetical protein,0.5681,26,0.9999998609133576,2407.999665079365,94.0,0.9999777974049721,2407.9465361511725,83.0,nonessential
1904,HNEAP_RS09885,WP_012824841.1,502587099.0,2127020,2129941,2921.0,-,DUF2339 domain-containing protein,0.5866,47,0.9999999999999999,2407.9999999999995,262.0,0.9999999999999999,2407.9999999999995,253.0,nonessential
1905,HNEAP_RS09890,WP_041600425.1,753844808.0,2130091,2130270,179.0,+,hypothetical protein,0.5111,6,0.997779777426312,2402.653704042559,15.0,0.9993919704884153,2406.535864936104,16.0,nonessential
1906,HNEAP_RS09895,WP_012824842.1,502587100.0,2130303,2131508,1205.0,+,ADP-forming succinate--CoA ligase subunit beta,0.5929,12,3.254343516879838e-20,7.83645918864665e-17,1.0,1.4086344493644848e-19,3.3919917540696794e-16,1.0,essential
1907,HNEAP_RS09900,WP_012824843.1,502587101.0,2131505,2132392,887.0,+,succinate--CoA ligase subunit alpha,0.6059,15,2.509221529201894e-16,6.042205442318161e-13,0.0,2.7563728264495856e-14,6.637345766090602e-11,1.0,essential
1908,HNEAP_RS09905,WP_012824844.1,502587102.0,2132445,2134130,1685.0,+,NAD+ synthase,0.6008,34,1.6347280581552235e-28,3.936425164037778e-25,1.0,1.2840048980170695e-27,3.0918837944251034e-24,1.0,essential
1909,HNEAP_RS09910,WP_012824845.1,502587103.0,2134186,2134371,185.0,+,4-oxalocrotonate tautomerase,0.5376,4,0.06188618738185319,149.02193921550247,3.0,0.07177235437853191,172.82782934350485,3.0,nonessential
1910,HNEAP_RS09915,WP_012824846.1,502587104.0,2134383,2135084,701.0,+,two-component system response regulator CreB,0.584,8,0.9937906161199561,2393.0478036168543,41.0,0.9962667113358411,2399.0102408967055,41.0,nonessential
1911,HNEAP_RS09920,WP_012824847.1,502587105.0,2135081,2136511,1430.0,+,two-component system sensor histidine kinase CreC,0.5549,26,0.4945468726163208,1190.8688692601004,56.0,0.6389514905563434,1538.5951892596747,57.0,nonessential
1912,HNEAP_RS09925,WP_012824848.1,502587106.0,2136601,2138616,2015.0,+,trypsin,0.5565,43,0.999998859504659,2407.997253687219,124.0,0.9999995813538325,2407.9989919000286,123.0,nonessential
1913,HNEAP_RS09930,WP_012824849.1,502587107.0,2138603,2139358,755.0,+,exosortase K,0.5661,20,0.8862756511527352,2134.1517679757862,36.0,0.8480331122806326,2042.0637343717633,34.0,nonessential
1914,HNEAP_RS09935,WP_012824850.1,502587108.0,2139340,2140398,1058.0,-,NUDIX hydrolase,0.5675,17,2.9283765250995607e-06,0.007051530672439742,16.0,8.543563939801239e-07,0.0020572901967041385,14.0,essential
1915,HNEAP_RS09940,WP_012824851.1,502587109.0,2140429,2141655,1226.0,-,bifunctional ornithine acetyltransferase/N-acetylglutamate synthase,0.5974,17,2.736801598803586e-22,6.590218249919035e-19,0.0,1.2543662412734258e-21,3.0205139089864094e-18,0.0,essential
1916,HNEAP_RS09945,WP_081441144.1,1174219963.0,2141741,2143087,1346.0,-,DUF945 domain-containing protein,0.5449,20,0.29727138286054805,715.8294899281997,49.0,0.3254744741167896,783.7425336732293,48.0,nonessential
1917,HNEAP_RS09950,WP_012824853.1,502587111.0,2143151,2145913,2762.0,-,preprotein translocase subunit SecA,0.5632,42,2.567595949573154e-36,6.182771046572154e-33,9.0,4.826942515968083e-36,1.1623277578451143e-32,8.0,essential
1918,HNEAP_RS09955,WP_012824854.1,502587112.0,2146210,2146656,446.0,+,DUF721 domain-containing protein,0.5548,9,0.003046154293702048,7.3351395392345315,7.0,0.00431279440115935,10.385208917991713,7.0,nonessential
1919,HNEAP_RS09960,WP_012824855.1,502587113.0,2146713,2147630,917.0,-,UDP-3-O-acyl-N-acetylglucosamine deacetylase,0.5534,14,2.8962463583076535e-15,6.97416123080483e-12,1.0,8.768727316516414e-15,2.1115095378171527e-11,1.0,essential
1920,HNEAP_RS09965,WP_012824856.1,502587114.0,2147888,2149768,1880.0,-,molecular chaperone HtpG,0.5534,28,0.5948083915609705,1432.298606878817,76.0,0.6073379430091683,1462.4697667660773,74.0,nonessential
1921,HNEAP_RS09970,WP_012824857.1,502587115.0,2149951,2150298,347.0,-,50S ribosomal protein L19,0.5546,4,7.888622366747315e-07,0.0018995802659127535,0.0,1.2137746201080528e-06,0.002922769285220191,0.0,essential
1922,HNEAP_RS09975,WP_012824858.1,502587116.0,2150315,2151073,758.0,-,tRNA (guanosine(37)-N1)-methyltransferase TrmD,0.5665,10,1.5064197665554376e-12,3.6274587978654938e-09,1.0,1.1944448981892997e-13,2.876223314839834e-10,0.0,essential
1923,HNEAP_RS09980,WP_012824859.1,502587117.0,2151134,2151670,536.0,-,ribosome maturation factor RimM,0.5326,16,8.659297903201252e-09,2.0851589350908615e-05,1.0,7.277025200624173e-10,1.752307668310301e-06,0.0,essential
1924,HNEAP_RS09985,WP_012824860.1,502587118.0,2151677,2151937,260.0,-,30S ribosomal protein S16,0.5862,5,2.673916543214769e-05,0.06438791036061163,0.0,3.692884183821646e-05,0.08892465114642524,0.0,ambiguous
1925,HNEAP_RS09990,WP_012824861.1,502587119.0,2152104,2153399,1295.0,-,adenylosuccinate synthase,0.5833,30,4.515328057870024e-19,1.0872909963351017e-15,3.0,2.053491651431316e-18,4.9448078966466094e-15,3.0,essential
1926,HNEAP_RS09995,WP_012824862.1,502587120.0,2153392,2154591,1199.0,-,ATP phosphoribosyltransferase regulatory subunit,0.5725,21,8.168013050184624e-22,1.9668575424844575e-18,0.0,3.6202318267742334e-21,8.717518238872353e-18,0.0,essential
1927,HNEAP_RS10000,WP_081441145.1,1174219964.0,2154726,2154944,218.0,-,DUF2065 domain-containing protein,0.5297,5,0.23486614895166621,565.5576866756122,6.0,0.26270998749071756,632.6056498776479,6.0,nonessential
1928,HNEAP_RS10005,WP_012824864.1,502587122.0,2154960,2155841,881.0,-,protease modulator HflC,0.5295,13,9.493728946480559e-05,0.22860899303125184,15.0,1.0253871553328299e-05,0.024691322700414544,12.0,ambiguous
1929,HNEAP_RS10010,WP_012824865.1,502587123.0,2155838,2156974,1136.0,-,protease modulator HflK,0.5699,29,0.049312272545076044,118.74395228854311,34.0,0.016626076443150225,40.03559207510574,30.0,nonessential
1930,HNEAP_RS10015,WP_012824866.1,502587124.0,2157146,2158468,1322.0,-,GTPase HflX,0.5903,17,0.9999997299272771,2407.9993496648835,91.0,0.9999995273484353,2407.9988618550324,88.0,nonessential
1931,HNEAP_RS10020,WP_012824867.1,502587125.0,2158468,2158746,278.0,-,RNA chaperone Hfq,0.5018,5,0.4534078463679291,1091.8060940539733,10.0,0.49425784309867427,1190.1728861816077,10.0,nonessential
1932,HNEAP_RS10025,WP_012824868.1,502587126.0,2158944,2159921,977.0,-,tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA,0.6022,14,0.9999999814287187,2407.9999552803547,76.0,0.9999997847125158,2407.999481587738,71.0,nonessential
1933,HNEAP_RS10030,WP_012824869.1,502587127.0,2159921,2161774,1853.0,-,DNA mismatch repair endonuclease MutL,0.6192,21,0.999999999995896,2407.9999999901174,137.0,0.9999999999989971,2407.9999999975853,136.0,nonessential
1934,HNEAP_RS10035,WP_012824870.1,502587128.0,2162040,2163260,1220.0,-,N-acetylmuramoyl-L-alanine amidase,0.5708,28,4.611546576944754e-19,1.1104604157282967e-15,2.0,1.9713080580140547e-18,4.7469098036978436e-15,2.0,essential
1935,HNEAP_RS10040,WP_012824871.1,502587129.0,2163510,2163713,203.0,-,hypothetical protein,0.5196,4,0.999476904412861,2406.740385826169,18.0,0.9943362298133998,2394.3616413906666,15.0,nonessential
1936,HNEAP_RS10045,WP_012824872.1,502587130.0,2163753,2164280,527.0,-,tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE,0.5511,10,6.053710441697775e-06,0.014577334743608242,4.0,1.865820057597253e-06,0.004492894698694186,3.0,essential
1937,HNEAP_RS10050,WP_012824873.1,502587132.0,2164317,2165879,1562.0,-,bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase,0.6008,23,0.9999999999999999,2407.9999999999995,145.0,0.9999999999999999,2407.9999999999995,142.0,nonessential
1938,HNEAP_RS10055,WP_012824874.1,502587133.0,2165889,2166899,1010.0,-,tryptophan--tRNA ligase,0.5559,22,8.843219848003297e-11,2.129447339399194e-07,7.0,6.126927065760102e-12,1.4753640374350324e-08,5.0,essential
1939,HNEAP_RS10060,WP_012824875.1,502587134.0,2167115,2167351,236.0,+,50S ribosomal protein L28,0.5654,4,7.067361032314671e-05,0.17018205365813727,0.0,9.473968398501837e-05,0.22813315903592424,0.0,ambiguous
1940,HNEAP_RS10065,WP_012824876.1,502587135.0,2167404,2167559,155.0,+,50S ribosomal protein L33,0.4615,3,0.8352775219246427,2011.3482727945395,8.0,0.7513625811488928,1809.2810954065337,7.0,nonessential
1941,HNEAP_RS10070,WP_012824877.1,502587136.0,2167684,2168529,845.0,+,bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase,0.5615,20,0.9998232592512715,2407.5744082770616,55.0,0.9999554434174637,2407.8927077492526,56.0,nonessential
1942,HNEAP_RS10075,WP_012824878.1,502587137.0,2168622,2168894,272.0,+,30S ribosomal protein S20,0.5385,5,0.00020133798459779972,0.48482186691150175,1.0,0.00027413348390067753,0.6601134292328315,1.0,nonessential
1943,HNEAP_RS10080,WP_012824879.1,502587138.0,2169063,2169692,629.0,+,dioxygenase,0.5794,13,0.3935597236499618,947.691814549108,23.0,0.3719094076179759,895.557853544086,22.0,nonessential
1944,HNEAP_RS10085,WP_012824880.1,502587139.0,2169947,2170684,737.0,-,orotate phosphoribosyltransferase,0.5379,16,1.0907442667226818e-13,2.6265121942682176e-10,0.0,2.72387129821169e-13,6.559082086093749e-10,0.0,essential
1945,HNEAP_RS10090,WP_012824881.1,502587140.0,2170746,2173328,2582.0,-,ATP-dependent chaperone ClpB,0.5641,35,0.9326939281759788,2245.926979047757,117.0,0.9653967652531824,2324.6754107296633,117.0,nonessential
1946,HNEAP_RS10095,WP_041600427.1,753844810.0,2173355,2173534,179.0,+,hypothetical protein,0.5111,1,0.8982730959441398,2163.0416150334886,10.0,0.6153431204402358,1481.7462340200877,7.0,nonessential
1947,HNEAP_RS10100,WP_012824882.1,502587141.0,2173625,2174017,392.0,+,hypothetical protein,0.5573,1,0.9576945928252234,2306.128579523138,22.0,0.9477049722458892,2282.073573168101,21.0,nonessential
1948,HNEAP_RS10105,WP_012824883.1,502587142.0,2174365,2175225,860.0,-,UDP-2 3-diacylglucosamine diphosphatase,0.5563,18,0.8268084881118768,1990.9548393733994,39.0,0.9021632864881224,2172.4091938633987,40.0,nonessential
1949,HNEAP_RS10110,WP_081441146.1,1174219965.0,2175479,2175805,326.0,+,hypothetical protein,0.4985,9,0.9784356019919036,2356.072929596504,20.0,0.9839650979939455,2369.3879559694205,20.0,nonessential
1950,HNEAP_RS10115,WP_012824884.1,502587143.0,2175815,2176315,500.0,-,peptide deformylase,0.5709,6,0.3045025213085924,733.2420713110905,17.0,0.3535469254968736,851.3409965964717,17.0,nonessential
1951,HNEAP_RS10120,WP_012824885.1,502587144.0,2176318,2176854,536.0,-,amino acid-binding ACT domain-containing protein,0.5791,6,0.9400134526352888,2263.5523939457753,28.0,0.9025968736618956,2173.4532717778443,26.0,nonessential
1952,HNEAP_RS10125,WP_012824886.1,502587145.0,2176882,2177646,764.0,-,multi-copper polyphenol oxidoreductase,0.5948,14,0.9995031575621497,2406.8036034096563,49.0,0.9997476895044577,2407.3924363267342,49.0,nonessential
1953,HNEAP_RS10130,WP_012824887.1,502587146.0,2177652,2178674,1022.0,-,23S rRNA pseudouridine(1911/1915/1917) synthase RluD,0.6061,20,0.9996943608137185,2407.264020839434,63.0,0.9996105127489482,2407.062114699467,61.0,nonessential
1954,HNEAP_RS10135,WP_012824888.1,502587147.0,2178858,2179679,821.0,+,outer membrane protein assembly factor BamD,0.545,24,2.2500882232470896e-10,5.418212441578991e-07,4.0,5.514825613059054e-10,1.32797000762462e-06,4.0,essential
1955,HNEAP_RS10140,WP_012824889.1,502587148.0,2179768,2181069,1301.0,+,MFS transporter,0.5707,16,0.9999998653031145,2407.9996756498995,91.0,0.9999998712971733,2407.999690083593,89.0,nonessential
1956,HNEAP_RS10145,WP_012824890.1,502587149.0,2181127,2181894,767.0,-,disulfide bond isomerase DsbC/G-like protein,0.5651,14,0.9973595560184634,2401.64181089246,46.0,0.9985277656098968,2404.4548595886313,46.0,nonessential
1957,HNEAP_RS10150,WP_012824891.1,502587150.0,2181947,2182882,935.0,-,site-specific tyrosine recombinase XerD,0.5951,16,0.9929734753156362,2391.080128560052,52.0,0.9796774853847989,2359.063384806596,48.0,nonessential
1958,HNEAP_RS12360,WP_012824892.1,502587151.0,2182879,2184021,1142.0,-,hypothetical protein,0.6054,13,0.9999998258103631,2407.9995805513545,82.0,0.9999996269193399,2407.9991016217705,79.0,nonessential
1959,HNEAP_RS10160,WP_012824893.1,502587152.0,2184011,2185105,1094.0,-,ATPase AAA,0.6027,15,0.9999999999999202,2407.9999999998076,98.0,0.9999999999999191,2407.999999999805,96.0,nonessential
1960,HNEAP_RS10165,WP_012824894.1,502587153.0,2185303,2187255,1952.0,+,acetate--CoA ligase,0.5837,37,0.9318579947934923,2243.9140514627293,90.0,0.8638365999566674,2080.118532695655,84.0,nonessential
1961,HNEAP_RS10170,WP_081441147.1,1174219966.0,2187252,2188046,794.0,+,hypothetical protein,0.5296,17,0.18215276247337817,438.62385203589463,26.0,0.17577155665557945,423.2579084266353,25.0,nonessential
1962,HNEAP_RS10175,WP_012824896.1,502587155.0,2188306,2188698,392.0,-,30S ribosomal protein S9,0.5674,6,1.888439984715766e-05,0.04547363483195564,2.0,2.0746810697119665e-07,0.0004995832015866415,0.0,essential
1963,HNEAP_RS10180,WP_012824897.1,502587156.0,2188716,2189144,428.0,-,50S ribosomal protein L13,0.5291,10,2.967439288505232e-08,7.145593806720598e-05,0.0,5.048960556702721e-08,0.00012157897020540151,0.0,essential
1964,HNEAP_RS10185,WP_012824898.1,502587157.0,2189471,2190715,1244.0,+,(Fe-S)-binding protein,0.596,21,0.9999999999999999,2407.9999999999995,125.0,0.9999999999999999,2407.9999999999995,123.0,nonessential
1965,HNEAP_RS10190,WP_012824899.1,502587158.0,2190770,2191084,314.0,+,hypothetical protein,0.419,14,0.7317506338728,1762.0555263657025,14.0,0.8422656922618135,2028.1757869664468,15.0,nonessential
1966,HNEAP_RS10195,WP_012824900.1,502587159.0,2191094,2191510,416.0,-,peroxiredoxin,0.5659,4,0.9544907419329114,2298.4137065744508,23.0,0.9659320445290733,2325.9643632260086,23.0,nonessential
1967,HNEAP_RS10200,WP_012824901.1,502587160.0,2191507,2192316,809.0,-,indole-3-glycerol-phosphate synthase,0.584,7,4.0164961443282925e-11,9.671722715542529e-08,3.0,1.000105944228921e-10,2.4082551137032417e-07,3.0,essential
1968,HNEAP_RS10205,WP_012824902.1,502587161.0,2192309,2193367,1058.0,-,anthranilate phosphoribosyltransferase,0.6081,14,2.46609226307837e-19,5.938350169492716e-16,0.0,9.174619609513388e-19,2.209248401970824e-15,0.0,essential
1969,HNEAP_RS10210,WP_012824903.1,502587162.0,2193678,2194604,926.0,+,glycine--tRNA ligase subunit alpha,0.5912,21,5.171436333442334e-17,1.245281869092914e-13,0.0,1.6330610108307242e-16,3.932410914080384e-13,0.0,essential
1970,HNEAP_RS10215,WP_012824904.1,502587163.0,2194652,2196730,2078.0,+,glycine--tRNA ligase subunit beta,0.5974,27,2.8337306738148585e-37,6.823623462546179e-34,0.0,3.7413013205738026e-36,9.009053579941717e-33,0.0,essential
1971,HNEAP_RS10220,WP_012824905.1,502587164.0,2196737,2197510,773.0,+,1-acyl-sn-glycerol-3-phosphate acyltransferase,0.5633,14,8.363289503297002e-13,2.013880112393918e-09,1.0,2.1177959874051087e-12,5.099652737671502e-09,1.0,essential
1972,HNEAP_RS10225,WP_012824906.1,502587165.0,2197495,2197974,479.0,-,hypothetical protein,0.5583,7,0.982417837035387,2365.6621515812117,28.0,0.9795411649305654,2358.7351251528016,27.0,nonessential
1973,HNEAP_RS10230,WP_012824907.1,502587166.0,2198141,2198851,710.0,+,hypothetical protein,0.5527,13,0.9814095965881279,2363.2343085842117,39.0,0.9880338460439165,2379.185501273751,39.0,nonessential
1974,HNEAP_RS10240,WP_012824908.1,502587167.0,2199465,2200007,542.0,-,rRNA large subunit pseudouridine synthase E,0.5654,7,0.08788560202254156,211.62852967028007,15.0,0.11184686320292421,269.3272465926415,15.0,nonessential
1975,HNEAP_RS10245,WP_012824909.1,502587168.0,2200021,2200995,974.0,-,5'-3' exonuclease,0.6154,15,0.9901095936900528,2384.183901605647,53.0,0.9943653281709,2394.431710235527,53.0,nonessential
1976,HNEAP_RS10250,WP_041600431.1,753844814.0,2200992,2202254,1262.0,-,malate dehydrogenase,0.6002,23,1.9841352761574786e-15,4.777797744987208e-12,6.0,8.945318909038508e-17,2.1540327932964727e-13,4.0,essential
1977,HNEAP_RS10255,WP_012824911.1,502587170.0,2202630,2202944,314.0,+,chorismate mutase,0.5143,7,0.9999893003267117,2407.9742351867217,29.0,0.9999839442627932,2407.9613377848063,28.0,nonessential
1978,HNEAP_RS10260,WP_012824912.1,502587171.0,2203075,2204169,1094.0,+,phosphate porin,0.5763,18,0.9998492883350699,2407.637086310848,68.0,0.9995047212124504,2406.8073686795806,64.0,nonessential
1979,HNEAP_RS10265,WP_012824913.1,502587172.0,2204266,2204502,236.0,+,hypothetical protein,0.3755,10,0.04087669363130401,98.43107826418004,4.0,0.04902048264918845,118.04132221924579,4.0,nonessential
1980,HNEAP_RS10270,WP_012824914.1,502587173.0,2204620,2205594,974.0,+,zinc ribbon domain-containing protein,0.4144,45,0.028650183424804864,68.98964168693011,27.0,0.0429178223310409,103.34611617314648,27.0,nonessential
1981,HNEAP_RS10275,WP_012824915.1,502587174.0,2206117,2207964,1847.0,-,GGDEF domain-containing response regulator,0.5482,27,0.9516548227790875,2291.5848132520427,87.0,0.9561269314739187,2302.353650989196,85.0,nonessential
1982,HNEAP_RS10280,WP_012824916.1,502587175.0,2208018,2211521,3503.0,-,sensor histidine kinase,0.5374,70,0.6857205021875972,1651.214969267734,144.0,0.7234030679130623,1741.9545875346541,141.0,nonessential
1983,HNEAP_RS10285,WP_012824917.1,502587176.0,2211863,2212513,650.0,-,cell envelope biogenesis protein OmpA,0.596,22,0.999055054822744,2405.7245720131677,42.0,0.999719493866896,2407.3245412314855,43.0,nonessential
1984,HNEAP_RS10290,WP_012824918.1,502587177.0,2212638,2213801,1163.0,-,8-amino-7-oxononanoate synthase,0.6306,19,1.7220913436269196e-19,4.1467959554536226e-16,1.0,1.487598557094354e-20,3.582137325483204e-17,0.0,essential
1985,HNEAP_RS10295,WP_012824919.1,502587178.0,2213831,2215792,1961.0,+,sensor histidine kinase,0.5622,34,0.11440711556827206,275.4923342883991,67.0,3.859362117359998e-06,0.009293343978602875,40.0,ambiguous
1986,HNEAP_RS10300,WP_012824920.1,502587179.0,2215848,2217227,1379.0,+,sigma-54-dependent Fis family transcriptional regulator,0.5703,21,7.306913611617503e-12,1.7595047976774947e-08,13.0,4.037001245377037e-10,9.721098998867905e-07,15.0,essential
1987,HNEAP_RS10305,WP_012824921.1,502587180.0,2217243,2218322,1079.0,-,hypothetical protein,0.5435,30,0.9999999999999999,2407.9999999999995,149.0,0.9999999999999999,2407.9999999999995,150.0,nonessential
1988,HNEAP_RS10310,WP_012824922.1,502587181.0,2218620,2219090,470.0,+,thiosulfate oxidation carrier protein SoxY,0.5456,12,0.0016250039887706642,3.9130096049597594,7.0,0.0002495387499336833,0.6008893098403094,5.0,nonessential
1989,HNEAP_RS10315,WP_012824923.1,502587182.0,2219148,2219453,305.0,+,thiosulfate oxidation carrier complex protein SoxZ,0.4641,8,4.32207867457261e-06,0.010407565448370846,0.0,6.312174255325463e-06,0.015199715606823715,0.0,essential
1990,HNEAP_RS10320,WP_012824924.1,502587183.0,2219729,2220700,971.0,-,prolyl aminopeptidase,0.5885,16,0.9989634130329974,2405.5038985834576,58.0,0.9991603251955562,2405.978063070899,57.0,nonessential
1991,HNEAP_RS10325,WP_012824925.1,502587184.0,2220814,2221656,842.0,+,tRNA 2-thiocytidine(32) synthetase TtcA,0.5872,11,0.9864489276541105,2375.369017791098,46.0,0.9874494312429413,2377.7782304330026,45.0,nonessential
1992,HNEAP_RS10330,WP_012824926.1,502587185.0,2221653,2222594,941.0,+,lipid A biosynthesis acyltransferase,0.5998,11,0.45377710943168964,1092.6952795115087,36.0,0.39434291244977765,949.5777331790646,34.0,nonessential
1993,HNEAP_RS10335,WP_012824927.1,502587186.0,2222591,2223574,983.0,-,lipid A biosynthesis acyltransferase,0.5772,19,2.1402696047861365e-16,5.153769208325016e-13,1.0,1.742739922783765e-17,4.196517734063306e-14,0.0,essential
1994,HNEAP_RS10340,WP_012824928.1,502587187.0,2223571,2225022,1451.0,-,potassium transporter,0.553,29,5.6100981780178e-23,1.3509116412666861e-19,2.0,3.194243665408995e-22,7.69173874630486e-19,2.0,essential
1995,HNEAP_RS10345,WP_012824929.1,502587188.0,2225052,2226428,1376.0,-,Trk system potassium transporter TrkA,0.5955,16,3.643354207906204e-23,8.773196932638139e-20,1.0,3.476444743905828e-24,8.371278943325235e-21,0.0,essential
1996,HNEAP_RS10350,WP_012824930.1,502587189.0,2226454,2227839,1385.0,-,sigma-54-dependent Fis family transcriptional regulator,0.57,24,4.3728879087891505e-25,1.0529914084364275e-21,0.0,2.4417319688857315e-24,5.879690581076842e-21,0.0,essential
1997,HNEAP_RS10355,WP_081441148.1,1174219967.0,2227852,2230347,2495.0,-,hypothetical protein,0.5629,42,4.944649099621731e-15,1.1906715031889127e-11,33.0,4.1087182544467984e-15,9.89379355670789e-12,31.0,essential
1998,HNEAP_RS10360,WP_081441149.1,1174219968.0,2230299,2230943,644.0,-,DUF4390 domain-containing protein,0.569,4,0.1528785602605395,368.1315731073791,20.0,0.0382928474869521,92.20917674858066,16.0,nonessential
1999,HNEAP_RS10365,WP_081441150.1,1174219969.0,2230909,2232453,1544.0,-,16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB,0.5935,14,0.9999999886715515,2407.999972721096,108.0,0.9999996781575149,2407.999225003296,100.0,nonessential
2000,HNEAP_RS10370,WP_012824934.1,502587193.0,2232386,2233321,935.0,-,methionyl-tRNA formyltransferase,0.6122,23,1.4239040107253298e-15,3.428760857826594e-12,1.0,4.408414367921763e-15,1.0615461797955604e-11,1.0,essential
2001,HNEAP_RS10375,WP_012824935.1,502587194.0,2233318,2233833,515.0,-,peptide deformylase,0.5543,6,1.616146080446969e-06,0.0038916797617163015,3.0,2.7982948522477473e-06,0.006738294004212575,3.0,essential
2002,HNEAP_RS10380,WP_081441151.1,1174219970.0,2234184,2235374,1190.0,+,LysM peptidoglycan-binding domain-containing protein,0.5542,28,0.34974075348376754,842.1757343889122,44.0,0.49066439596914224,1181.5198654936946,45.0,nonessential
2003,HNEAP_RS10385,WP_081441194.1,1174220013.0,2235483,2236559,1076.0,+,DNA-protecting protein DprA,0.6026,14,0.9999454970926086,2407.8687569990016,69.0,0.9999618724323205,2407.9081888170276,68.0,nonessential
2004,HNEAP_RS10390,WP_012824939.1,502587198.0,2236607,2237107,500.0,+,DUF494 domain-containing protein,0.5469,6,0.22610020908080358,544.449303466575,16.0,0.3535469254968736,851.3409965964717,17.0,nonessential
2005,HNEAP_RS10395,WP_012824940.1,502587199.0,2237151,2239655,2504.0,+,DNA topoisomerase I,0.584,44,9.435362399323655e-37,2.272035265757136e-33,5.0,1.8066713617563392e-35,4.350464639109265e-32,5.0,essential
2006,HNEAP_RS10400,WP_012824941.1,502587200.0,2239725,2240282,557.0,+,tRNA threonylcarbamoyladenosine biosynthesis protein RimN,0.6308,9,0.0011936388072189648,2.8742822477832672,9.0,0.00428884210613725,10.3275317915785,10.0,nonessential
2007,HNEAP_RS10405,WP_012824942.1,502587201.0,2240463,2241404,941.0,+,oxygen-dependent coproporphyrinogen oxidase,0.5924,22,2.817038542406914e-17,6.78342881011585e-14,0.0,3.505070886766913e-15,8.440210695334726e-12,1.0,essential
2008,HNEAP_RS10410,WP_012824943.1,502587202.0,2241428,2242264,836.0,-,nuclease,0.5687,18,0.9992856352593528,2406.2798097045215,52.0,0.9989426456518204,2405.4538907295837,50.0,nonessential
2009,HNEAP_RS10415,WP_012824944.1,502587203.0,2242284,2242529,245.0,-,type B 50S ribosomal protein L31,0.4878,6,0.0742061967755056,178.6885218354175,5.0,0.03928928323179412,94.60859402216025,4.0,nonessential
2010,HNEAP_RS10420,WP_012824945.1,502587204.0,2242722,2243465,743.0,-,ComF family protein,0.5618,12,0.9766577986495243,2351.7919791480545,40.0,0.9848804756704955,2371.592185414553,40.0,nonessential
2011,HNEAP_RS10425,WP_012824946.1,502587205.0,2243511,2243933,422.0,+,hypothetical protein,0.4917,15,0.9982244812325661,2403.724550808019,29.0,0.9977898452759035,2402.677947424376,28.0,nonessential
2012,HNEAP_RS10430,WP_012824947.1,502587206.0,2243987,2245030,1043.0,+,biotin synthase BioB,0.5996,11,2.8947758512904967e-11,6.970620249907515e-08,7.0,8.51339883715804e-11,2.050026439987656e-07,7.0,essential
2013,HNEAP_RS10435,WP_012824948.1,502587207.0,2245352,2247055,1703.0,+,hypothetical protein,0.5763,45,0.9999999999967808,2407.9999999922484,129.0,0.9999999999982147,2407.999999995701,127.0,nonessential
2014,HNEAP_RS10440,WP_012824949.1,502587208.0,2247324,2247743,419.0,-,DUF4168 domain-containing protein,0.5524,8,0.9513448376382747,2290.8383690329656,23.0,0.9780688210363568,2355.189721055547,24.0,nonessential
2015,HNEAP_RS10445,WP_012824950.1,502587209.0,2247894,2249294,1400.0,-,sigma-54-dependent Fis family transcriptional regulator,0.5739,26,0.793893553008705,1911.6956756449617,61.0,0.7844908324747701,1889.0539245992466,59.0,nonessential
2016,HNEAP_RS10450,WP_012824951.1,502587210.0,2249291,2250742,1451.0,-,signal transduction histidine kinase,0.5551,31,0.9744103090026972,2346.380024078495,72.0,0.9406511953777528,2265.0880784696287,67.0,nonessential
2017,HNEAP_RS10455,WP_012824952.1,502587211.0,2250990,2251271,281.0,-,XRE family transcriptional regulator,0.5674,4,0.01233664055075372,29.70663044621496,4.0,0.01560139831461764,37.568167141599275,4.0,nonessential
2018,HNEAP_RS10460,WP_012824953.1,502587212.0,2251268,2251606,338.0,-,type II toxin-antitoxin system RelE/ParE family toxin,0.5192,4,0.9975813597791195,2402.17591434812,24.0,0.9983812580922641,2404.102069486172,24.0,nonessential
2019,HNEAP_RS10465,WP_081441152.1,1174219971.0,2251878,2252390,512.0,-,hypothetical protein,0.5828,15,0.8292370526456163,1996.802822770644,24.0,0.8106380362955301,1952.0163913996364,23.0,nonessential
2020,HNEAP_RS10470,WP_041600434.1,753844817.0,2252367,2252609,242.0,+,hypothetical protein,0.5432,9,0.8959683131415599,2157.491698044876,13.0,0.9508690248421152,2289.6926118198135,14.0,nonessential
2021,HNEAP_RS10475,WP_012824954.1,502587213.0,2252652,2252960,308.0,-,hypothetical protein,0.4013,17,0.01608890399696584,38.742080824693744,5.0,0.020441274637137012,49.22258932622592,5.0,nonessential
2022,HNEAP_RS10480,WP_012824955.1,502587214.0,2253635,2254642,1007.0,-,hypothetical protein,0.5377,39,0.999993270099565,2407.9837943997522,69.0,0.9999975434237129,2407.994084564301,69.0,nonessential
2023,HNEAP_RS10485,WP_012824956.1,502587215.0,2254933,2259978,5045.0,-,hypothetical protein,0.5666,149,0.9999999999999999,2407.9999999999995,328.0,0.9999999999999999,2407.9999999999995,319.0,nonessential
2024,HNEAP_RS10490,WP_041600435.1,753844818.0,2260069,2260764,695.0,-,hypothetical protein,0.556,16,0.9863439377378339,2375.1162020727043,39.0,0.9946639337788846,2395.150752539554,40.0,nonessential
2025,HNEAP_RS10495,WP_012824958.1,502587217.0,2261083,2262591,1508.0,-,anthranilate synthase component I,0.5918,30,2.5377193037212686e-20,6.110828083360815e-17,5.0,1.4122335511047344e-19,3.4006583910602006e-16,5.0,essential
2026,HNEAP_RS10500,WP_041601053.1,753845436.0,2262695,2263375,680.0,-,phosphoglycolate phosphatase,0.5389,15,3.192858158730454e-11,7.688402446222933e-08,1.0,2.552445122462663e-12,6.146287854890093e-09,0.0,essential
2027,HNEAP_RS10505,WP_012824960.1,502587219.0,2263398,2264084,686.0,-,phosphoglycolate phosphatase,0.5575,14,0.9187241681939693,2212.287797011078,34.0,0.736545474345201,1773.601502223244,29.0,nonessential
2028,HNEAP_RS10510,WP_012824961.1,502587220.0,2264084,2264779,695.0,-,ribulose-phosphate 3-epimerase,0.5647,9,5.976052998158998e-13,1.4390335619566867e-09,0.0,1.416535656501136e-12,3.4110178608547357e-09,0.0,essential
2029,HNEAP_RS12365,WP_012824962.1,502587221.0,2264888,2265472,584.0,-,SPOR domain-containing protein,0.5709,7,0.371914188773895,895.5693665675391,21.0,0.4289630178602401,1032.942947007458,21.0,nonessential
2030,HNEAP_RS10520,WP_012824963.1,502587222.0,2265503,2267269,1766.0,-,arginine--tRNA ligase,0.5739,39,8.705248107476167e-32,2.0962237442802608e-28,0.0,7.801603280270426e-31,1.8786260698891186e-27,0.0,essential
2031,HNEAP_RS12370,WP_012824964.1,502587223.0,2267473,2272557,5084.0,-,outer membrane autotransporter barrel domain-containing protein,0.6002,114,0.9999999999999999,2407.9999999999995,534.0,0.9999999999999999,2407.9999999999995,520.0,nonessential
2032,HNEAP_RS10530,WP_012824965.1,502587224.0,2272682,2273545,863.0,+,AraC family transcriptional regulator,0.5683,13,0.999995851975771,2407.9900115576565,62.0,0.9999984127660985,2407.996177940765,62.0,nonessential
2033,HNEAP_RS10535,WP_012824966.1,502587225.0,2273640,2274251,611.0,+,GTP cyclohydrolase I FolE,0.5703,12,0.9999641965973055,2407.9137854063115,45.0,0.9999276770804199,2407.825846409651,43.0,nonessential
2034,HNEAP_RS10540,WP_012824967.1,502587226.0,2274262,2275017,755.0,+,dihydrofolate reductase,0.5873,16,0.9967710529231606,2400.2246954389707,45.0,0.9981697975405408,2403.592872477622,45.0,nonessential
2035,HNEAP_RS10545,WP_041600436.1,753844819.0,2275316,2275579,263.0,-,hypothetical protein,0.4621,7,0.0066852058345585426,16.09797564961697,3.0,0.008505763308679902,20.481878047301205,3.0,nonessential
2036,HNEAP_RS10550,WP_041600437.1,753844820.0,2275798,2276565,767.0,-,nodulation protein NodJ,0.5521,17,0.8264122508169578,1990.0006999672344,35.0,0.8677267385045178,2089.485986318879,35.0,nonessential
2037,HNEAP_RS10555,WP_041601057.1,753845440.0,2276643,2277575,932.0,-,ABC transporter,0.5798,9,0.9999579041601026,2407.898633217527,62.0,0.999941675103717,2407.8595536497505,60.0,nonessential
2038,HNEAP_RS10560,WP_012824971.1,502587231.0,2277583,2278851,1268.0,-,3-deoxy-D-manno-octulosonic acid transferase,0.5847,31,2.6676779081661993e-21,6.423768402864208e-18,1.0,1.2486212447761746e-20,3.0066799574210284e-17,1.0,essential
2039,HNEAP_RS10565,WP_012824972.1,502587232.0,2278897,2279847,950.0,+,lipid A biosynthesis acyltransferase,0.5783,15,1.5852727884826486e-14,3.8173368746662175e-11,2.0,2.484774880421363e-15,5.9833379120546414e-12,1.0,essential
2040,HNEAP_RS10570,WP_081441153.1,1174219972.0,2279848,2281002,1154.0,-,glycosyltransferase family 1 protein,0.5758,23,0.9430196657644063,2270.7913551606903,56.0,0.9639108405004224,2321.097303925017,56.0,nonessential
2041,HNEAP_RS10575,WP_012824974.1,502587234.0,2280965,2282242,1277.0,-,O-antigen polymerase,0.5642,27,0.8678070144109513,2089.6792907015706,58.0,0.7840720108047999,1888.0454020179582,54.0,nonessential
2042,HNEAP_RS10580,WP_012824975.1,502587235.0,2282239,2283072,833.0,-,glycosyltransferase family 2 protein,0.5576,15,0.05921975890006476,142.60117943135594,24.0,0.05613307174453971,135.16843676085162,23.0,nonessential
2043,HNEAP_RS10585,WP_012824976.1,502587236.0,2283069,2283839,770.0,-,polysaccharide deacetylase,0.5707,13,0.982647671975757,2366.215594117623,42.0,0.9748473892310282,2347.432513268316,40.0,nonessential
2044,HNEAP_RS10590,WP_012824977.1,502587237.0,2283876,2284514,638.0,-,hypothetical protein,0.5759,12,0.8042377665616115,1936.6045418803606,29.0,0.5885665263106503,1417.268195356046,25.0,nonessential
2045,HNEAP_RS10595,WP_012824978.1,502587238.0,2284529,2285623,1094.0,-,glycosyltransferase family 1 protein,0.5571,25,0.9999991738876697,2407.9980107215088,77.0,0.99999949313431,2407.9987794674184,76.0,nonessential
2046,HNEAP_RS10600,WP_012824979.1,502587239.0,2285627,2286790,1163.0,-,glycosyl transferase,0.579,22,8.284711320761967e-15,1.9949584860394814e-11,5.0,2.664641313386716e-16,6.416456282635212e-13,3.0,essential
2047,HNEAP_RS10605,WP_012824980.1,502587240.0,2286881,2287552,671.0,+,hypothetical protein,0.5164,22,0.00016767167814224466,0.4037534009665251,10.0,9.420314608792288e-06,0.02268411757797183,7.0,ambiguous
2048,HNEAP_RS10610,WP_012824981.1,502587241.0,2287549,2288553,1004.0,+,hypothetical protein,0.5552,22,1.982493595123329e-15,4.7738445770569764e-12,2.0,6.482619273469875e-15,1.561014721051546e-11,2.0,essential
2049,HNEAP_RS10615,WP_012824983.1,502587243.0,2288804,2289016,212.0,-,zinc-finger domain-containing protein,0.5211,6,0.5338113940228146,1285.4178368069377,8.0,0.5696579020279979,1371.736228083419,8.0,nonessential
2050,HNEAP_RS10620,WP_012824984.1,502587244.0,2289013,2289948,935.0,-,branched-chain amino acid transaminase,0.5256,30,3.591866165911869e-17,8.649213727515781e-14,0.0,1.1470043596338668e-16,2.761986497998351e-13,0.0,essential
2051,HNEAP_RS10625,WP_041601064.1,753845447.0,2290391,2290591,200.0,-,thiamine biosynthesis protein ThiS,0.5124,2,0.00030368365774538367,0.7312702478508839,0.0,0.00038929721614338323,0.9374276964732668,0.0,ambiguous
2052,HNEAP_RS10630,WP_041601065.1,753845448.0,2290632,2290925,293.0,-,hypothetical protein,0.4626,9,0.008831019499057104,21.265094953729506,4.0,0.011329073236158687,27.28040835267012,4.0,nonessential
2053,HNEAP_RS10660,WP_012824987.1,502587247.0,2296872,2298080,1208.0,-,tyrosine--tRNA ligase,0.5343,27,5.673164634738108e-22,1.3660980440449364e-18,0.0,2.5427229360420662e-21,6.122876829989296e-18,0.0,essential
2054,HNEAP_RS10665,WP_041600438.1,753844821.0,2298152,2299639,1487.0,+,hypothetical protein,0.5403,36,3.992973895069717e-17,9.615081139327879e-14,8.0,1.9719134904978241e-16,4.748367685118761e-13,8.0,essential
2055,HNEAP_RS10670,WP_012824989.1,502587249.0,2299645,2300820,1175.0,+,anhydro-N-acetylmuramic acid kinase,0.5587,21,0.9581724498725998,2307.27925929322,58.0,0.9524652344724845,2293.536284609743,56.0,nonessential
2056,HNEAP_RS10675,WP_012824990.1,502587250.0,2300840,2302009,1169.0,-,citrate synthase,0.5726,21,3.8425829720109864e-13,9.252939796602456e-10,7.0,1.9375838533033557e-13,4.665701918754481e-10,6.0,essential
2057,HNEAP_RS10680,WP_012824991.1,502587251.0,2302019,2302381,362.0,-,iron-sulfur cluster insertion protein ErpA,0.5041,11,0.5307949928465334,1278.1543427744525,14.0,0.46936093744315965,1130.2211373631285,13.0,nonessential
2058,HNEAP_RS10685,WP_012824992.1,502587252.0,2302476,2303510,1034.0,-,N-acetyl-gamma-glutamyl-phosphate reductase,0.572,23,2.142649428291823e-10,5.15949982332671e-07,8.0,1.14245803859342e-10,2.7510389569329553e-07,7.0,essential
2059,HNEAP_RS10690,WP_012824993.1,502587253.0,2303625,2305439,1814.0,+,Cl- channel voltage-gated family protein,0.5559,39,0.9999999999999999,2407.9999999999995,156.0,0.9999999999999999,2407.9999999999995,154.0,nonessential
2060,HNEAP_RS10695,WP_012824994.1,502587254.0,2305490,2306008,518.0,+,TlpA family protein disulfide reductase,0.5645,10,0.0012453247176560018,2.9987419201156524,8.0,0.00455808457008704,10.975867644769592,9.0,nonessential
2061,HNEAP_RS10700,WP_012824995.1,502587255.0,2306116,2306898,782.0,+,type I methionyl aminopeptidase,0.5696,17,5.874374385811121e-13,1.414549352103318e-09,1.0,1.5042414835082508e-12,3.622213492287868e-09,1.0,essential
2062,HNEAP_RS10705,WP_041600439.1,753844822.0,2306895,2309501,2606.0,+,[protein-PII] uridylyltransferase,0.5811,43,0.9999999884331632,2407.9999721470567,163.0,0.9999979274838725,2407.995009381165,148.0,nonessential
2063,HNEAP_RS10710,WP_012824997.1,502587257.0,2309498,2310166,668.0,+,pseudouridine synthase,0.6069,9,0.992527813540736,2390.0069750060925,39.0,0.997273373638906,2401.434283722486,40.0,nonessential
2064,HNEAP_RS10715,WP_012824998.1,502587258.0,2310176,2310880,704.0,-,DNA-binding response regulator,0.6028,9,0.9959060739493831,2398.141826070115,42.0,0.9959827689554018,2398.326507644608,41.0,nonessential
2065,HNEAP_RS10720,WP_012824999.1,502587259.0,2310885,2311988,1103.0,-,signal transduction histidine kinase LytS,0.5743,21,0.9999999999999994,2407.9999999999986,104.0,0.9999999999999994,2407.9999999999986,102.0,nonessential
2066,HNEAP_RS10725,WP_012825000.1,502587260.0,2312120,2313547,1427.0,+,argininosuccinate lyase,0.6015,20,7.981358962181348e-26,1.9219112380932685e-22,0.0,4.695232059602185e-25,1.1306118799522062e-21,0.0,essential
2067,HNEAP_RS12375,WP_049772532.1,908628499.0,2313614,2313835,221.0,-,hypothetical protein,0.5405,3,0.9924527662493673,2389.8262611284763,16.0,0.997536194561099,2402.067156503126,17.0,nonessential
2068,HNEAP_RS12380,WP_049772533.1,908628500.0,2313857,2314264,407.0,-,hypothetical protein,0.5956,3,0.2571648849551635,619.2530429720337,13.0,0.21086702854657283,507.76780474014737,12.0,nonessential
2069,HNEAP_RS10735,WP_012825001.1,502587261.0,2314369,2315046,677.0,+,pyridoxamine 5'-phosphate oxidase,0.5959,9,5.022477864266455e-09,1.2094126697153623e-05,3.0,7.462685416453384e-08,0.0001797014648281975,4.0,essential
2070,HNEAP_RS10740,WP_012825002.1,502587262.0,2315043,2315741,698.0,+,uracil-DNA glycosylase,0.5637,14,0.99999822071484,2407.9957154813346,54.0,0.9999930954926624,2407.983373946331,51.0,nonessential
2071,HNEAP_RS10745,WP_012825003.1,502587263.0,2315749,2316420,671.0,-,JAB domain-containing protein,0.5908,14,0.9999777820915137,2407.946499276365,49.0,0.999918331499733,2407.803342251357,46.0,nonessential
2072,HNEAP_RS10750,WP_012825004.1,502587264.0,2316572,2316802,230.0,-,hypothetical protein,0.5584,3,0.7942012703599272,1912.4366590267045,11.0,0.7258239823660383,1747.7841495374203,10.0,nonessential
2073,HNEAP_RS10755,WP_012825005.1,502587265.0,2317109,2317549,440.0,+,TonB-system energizer ExbB,0.5624,10,0.6134072016042202,1477.0845414629623,18.0,0.5701292586898399,1372.8712549251345,17.0,nonessential
2074,HNEAP_RS10760,WP_012825006.1,502587266.0,2317557,2317952,395.0,+,TonB system transport protein ExbD,0.5707,5,0.8385656746603589,2019.2661445821443,19.0,0.8678341124863718,2089.744542867183,19.0,nonessential
2075,HNEAP_RS10765,WP_012825007.1,502587268.0,2317949,2318782,833.0,+,energy transducer TonB,0.5791,10,0.9886242362576361,2380.607160908388,46.0,0.9762948837639465,2350.918080103583,43.0,nonessential
2076,HNEAP_RS10770,WP_012825008.1,502587269.0,2318767,2319369,602.0,-,thioredoxin family protein,0.5224,8,0.7785691412777114,1874.794492196729,27.0,0.7646157387713957,1841.1946989615208,26.0,nonessential
2077,HNEAP_RS10775,WP_012825009.1,502587270.0,2319503,2320462,959.0,+,hydroxymethylbilane synthase,0.6125,14,1.540356267603542e-12,3.709177892389329e-09,4.0,4.478289743050054e-12,1.0783721701264529e-08,4.0,essential
2078,HNEAP_RS10780,WP_012825010.1,502587271.0,2320524,2321294,770.0,+,uroporphyrinogen-III synthase,0.6096,12,2.325305196243995e-07,0.000559933491255554,7.0,4.884344977861502e-07,0.0011761502706690496,7.0,essential
2079,HNEAP_RS10785,WP_012825011.1,502587272.0,2321298,2322530,1232.0,+,hypothetical protein,0.5904,12,0.3707596494537871,892.7892358847193,46.0,0.4543529094746219,1094.0818060148895,46.0,nonessential
2080,HNEAP_RS10790,WP_012825012.1,502587273.0,2322527,2323729,1202.0,+,heme biosynthesis protein HemY,0.5786,17,0.9670415858841727,2328.6361388090877,60.0,0.9501342866891006,2287.923362347354,57.0,nonessential
2081,HNEAP_RS12385,WP_012825013.1,502587274.0,2323808,2325190,1382.0,-,GGDEF domain-containing protein,0.5517,25,0.000844004253649584,2.032362242788198,33.0,0.0028394392931316557,6.837369817861027,34.0,nonessential
2082,HNEAP_RS10800,WP_081441154.1,1174219973.0,2325209,2326090,881.0,-,hypothetical protein,0.542,23,0.9458886167782649,2277.6997892020618,44.0,0.9297869777415277,2238.927042401599,42.0,nonessential
2083,HNEAP_RS10805,WP_012825015.1,502587276.0,2326097,2326798,701.0,-,DSBA oxidoreductase,0.5342,18,0.0011995881367158595,2.8886082332117895,13.0,0.0019389106328360573,4.668896803869226,13.0,nonessential
2084,HNEAP_RS10810,WP_012825016.1,502587277.0,2326968,2328185,1217.0,-,c-type cytochrome biogenesis protein CcsB,0.5632,32,3.9403459293096605e-22,9.488352997777662e-19,0.0,1.7859187584777802e-21,4.300492370414495e-18,0.0,essential
2085,HNEAP_RS10815,WP_012825017.1,502587278.0,2328259,2330361,2102.0,-,cytochrome c biogenesis protein ResB,0.5064,56,9.366514510371885e-27,2.25545669409755e-23,8.0,9.912927389471935e-26,2.387032915384842e-22,8.0,essential
2086,HNEAP_RS10820,WP_012825018.1,502587279.0,2330561,2331226,665.0,-,cytochrome c4,0.5495,15,0.8449439240115162,2034.624969019731,31.0,0.7877135483774262,1896.8142244928424,29.0,nonessential
2087,HNEAP_RS10825,WP_012825019.1,502587280.0,2331521,2332204,683.0,+,YihA family ribosome biogenesis GTP-binding protein,0.5614,14,4.1489720832825337e-10,9.99072477654434e-07,2.0,9.113407221144781e-10,2.1945084588516636e-06,2.0,essential
2088,HNEAP_RS10830,WP_012825020.1,502587281.0,2332383,2335010,2627.0,+,sensor domain-containing diguanylate cyclase,0.5571,46,0.999999999988741,2407.9999999728884,177.0,0.9999999999893426,2407.9999999743372,173.0,nonessential
2089,HNEAP_RS10835,WP_012825021.1,502587282.0,2335047,2335967,920.0,-,LysR family transcriptional regulator,0.5798,16,5.018527082167321e-14,1.208461321385891e-10,2.0,1.4786841949237754e-13,3.560671541376451e-10,2.0,essential
2090,HNEAP_RS10840,WP_012825022.1,502587283.0,2335990,2337363,1373.0,-,glutathione-disulfide reductase,0.6194,25,4.673078808960375e-08,0.00011252773771976584,20.0,1.2892642030943435e-10,3.104548201051179e-07,14.0,essential
2091,HNEAP_RS10845,WP_012825023.1,502587284.0,2337532,2338269,737.0,-,glutathione amide-dependent peroxidase,0.5501,9,0.603735355187548,1453.7947352916156,30.0,0.2333155619835476,561.8238732563826,24.0,nonessential
2092,HNEAP_RS10850,WP_012825024.1,502587285.0,2338430,2339722,1292.0,-,diaminopimelate decarboxylase,0.5855,24,5.242257321584344e-15,1.26233556303751e-11,7.0,2.097716880044218e-14,5.051302247146477e-11,7.0,essential
2093,HNEAP_RS12580,WP_081441155.1,1174219974.0,2339724,2339885,161.0,-,hypothetical protein,0.5309,5,0.01127806004526001,27.157568588986106,1.0,0.01339962216903979,32.266290183047815,1.0,nonessential
2094,HNEAP_RS10855,WP_012825025.1,502587286.0,2340181,2342373,2192.0,-,catalase/peroxidase HPI,0.5878,34,0.9999993501833887,2407.9984352416,134.0,0.9999996476097586,2407.9991514442986,132.0,nonessential
2095,HNEAP_RS10860,WP_081441156.1,1174219975.0,2342484,2343788,1304.0,-,hypothetical protein,0.6084,13,0.9999948207644762,2407.9875284008585,85.0,0.9999844238267792,2407.9624925748844,81.0,nonessential
2096,HNEAP_RS10865,WP_081441157.1,1174219976.0,2343792,2344787,995.0,+,hypothetical protein,0.5612,17,0.9999999999999984,2407.9999999999964,96.0,0.9999999999999688,2407.999999999925,91.0,nonessential
2097,HNEAP_RS10870,WP_041600440.1,753844823.0,2345447,2345668,221.0,+,hypothetical protein,0.5135,4,0.8961838614519541,2158.010738376305,12.0,0.9127837960506995,2197.9833808900844,12.0,nonessential
2098,HNEAP_RS10875,WP_012825029.1,502587290.0,2345713,2346816,1103.0,+,tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA,0.5969,16,0.98998774036726,2383.890478804362,59.0,0.9944888858800618,2394.729237199189,59.0,nonessential
2099,HNEAP_RS10880,WP_012825030.1,502587291.0,2346806,2347930,1124.0,+,tRNA guanosine(34) transglycosylase Tgt,0.5724,19,0.9999766101749742,2407.9436773013376,73.0,0.9999726799622803,2407.934213349171,71.0,nonessential
2100,HNEAP_RS10885,WP_012825031.1,502587292.0,2348073,2348414,341.0,+,preprotein translocase subunit YajC,0.5497,3,0.01720107584836497,41.42019064286285,6.0,0.00889108901648212,21.409742351688948,5.0,nonessential
2101,HNEAP_RS10890,WP_012825032.1,502587293.0,2348588,2350450,1862.0,+,protein translocase subunit SecD,0.5813,30,1.7837888125701316e-33,4.295363460668877e-30,0.0,1.8010214501476448e-32,4.336859651955529e-29,0.0,essential
2102,HNEAP_RS10895,WP_012825033.1,502587294.0,2350475,2351413,938.0,+,protein translocase subunit SecF,0.558,14,1.2649496012888844e-15,3.0459986399036335e-12,1.0,3.930897457857337e-15,9.465601078520466e-12,1.0,essential
2103,HNEAP_RS10900,WP_012825034.1,502587295.0,2351501,2352280,779.0,-,inositol monophosphatase,0.5705,18,1.0965303357381697e-11,2.6404450484575125e-08,2.0,2.7127621621453638e-11,6.532331286446036e-08,2.0,essential
2104,HNEAP_RS10905,WP_012825035.1,502587296.0,2352401,2353216,815.0,+,TrmH family RNA methyltransferase,0.598,12,0.999999999518517,2407.999998840589,71.0,0.9999999992269188,2407.999998138421,69.0,nonessential
2105,HNEAP_RS10910,WP_012825036.1,502587297.0,2353213,2354055,842.0,+,serine O-acetyltransferase,0.6228,10,7.583722216922852e-10,1.8261603098350228e-06,5.0,1.8500797835574504e-09,4.454992118806341e-06,5.0,essential
2106,HNEAP_RS10915,WP_012825037.1,502587298.0,2354338,2354841,503.0,+,transcriptional regulator,0.5893,3,0.9999999999765062,2407.999999943427,54.0,0.9999999999767379,2407.999999943985,53.0,nonessential
2107,HNEAP_RS10920,WP_012825038.1,502587299.0,2354978,2355406,428.0,+,nucleoside-diphosphate kinase,0.5594,6,0.0017888736642772257,4.307607783579559,6.0,0.0008364137176925557,2.014084232203674,5.0,nonessential
2108,HNEAP_RS10925,WP_081441158.1,1174219977.0,2355348,2356607,1259.0,+,23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN,0.5794,21,0.061337797916651816,147.70141738329758,39.0,0.0913990394008425,220.08888687722873,39.0,nonessential
2109,HNEAP_RS10930,WP_012825040.1,502587301.0,2356607,2357437,830.0,+,type IV pilus biogenesis/stability protein PilW,0.5656,19,0.009566152133221938,23.035294336798426,20.0,0.024355704478120493,58.648536383314145,21.0,nonessential
2110,HNEAP_RS10935,WP_081441159.1,1174219978.0,2357413,2358579,1166.0,+,DUF4115 domain-containing protein,0.5861,19,4.84975210856015e-07,0.001167820307741284,17.0,1.2222661796650995e-06,0.00294321696063356,17.0,essential
2111,HNEAP_RS10940,WP_012825042.1,502587303.0,2358576,2359679,1103.0,+,4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase,0.5978,15,4.323669365224912e-17,1.0411395831461588e-13,2.0,1.5985317712734775e-16,3.8492645052265337e-13,2.0,essential
2112,HNEAP_RS10945,WP_012825043.1,502587304.0,2359716,2361008,1292.0,+,histidine--tRNA ligase,0.6118,14,2.795005906993724e-20,6.730374224040887e-17,2.0,1.3064392438161062e-19,3.1459056991091837e-16,2.0,essential
2113,HNEAP_RS10950,WP_012825044.1,502587305.0,2361096,2361761,665.0,+,hypothetical protein,0.5856,10,0.010572994875025553,25.45977165906153,15.0,0.008289653694184097,19.961486095595305,14.0,nonessential
2114,HNEAP_RS10955,WP_012825045.1,502587306.0,2361764,2362921,1157.0,+,outer membrane protein assembly factor BamB,0.5872,23,2.184656112865208e-19,5.260651919779421e-16,1.0,8.909284587146872e-19,2.1453557285849667e-15,1.0,essential
2115,HNEAP_RS10960,WP_012825046.1,502587308.0,2363000,2364373,1373.0,+,hypothetical protein,0.5946,18,0.9999986773376515,2407.9968150290647,91.0,0.9999987704583663,2407.997039263746,89.0,nonessential
2116,HNEAP_RS10965,WP_012825047.1,502587309.0,2364493,2365680,1187.0,+,amidohydrolase,0.6389,16,0.9933233383118583,2391.9225986549545,64.0,0.9923975904572989,2389.693397821176,62.0,nonessential
2117,HNEAP_RS10970,WP_012825048.1,502587310.0,2365922,2367220,1298.0,+,aspartate aminotransferase family protein,0.5828,19,0.9999777693648515,2407.9464686305623,82.0,0.9999867460427603,2407.968084470967,81.0,nonessential
2118,HNEAP_RS10975,WP_012825049.1,502587311.0,2367217,2368515,1298.0,+,aminopeptidase P family protein,0.5874,17,0.9640371133629863,2321.401368978071,64.0,0.9611068671019216,2314.345335981427,62.0,nonessential
2119,HNEAP_RS10980,WP_012825050.1,502587312.0,2368512,2369882,1370.0,+,succinate-semialdehyde dehydrogenase,0.6098,17,0.9981980048959092,2403.6607957893493,76.0,0.9991924192077657,2406.0553454522997,76.0,nonessential
2120,HNEAP_RS10985,WP_012825051.1,502587313.0,2370083,2371786,1703.0,+,ribosome biogenesis GTPase Der,0.6068,19,1.205091711402058e-24,2.901860841056156e-21,4.0,8.812130340715321e-24,2.1219609860442495e-20,4.0,essential
2121,HNEAP_RS10990,WP_012825052.1,502587314.0,2371798,2372664,866.0,-,ABC transporter ATP-binding protein,0.5075,25,0.45019328978150663,1084.0654417938679,33.0,0.3821536321994722,920.225946336329,31.0,nonessential
2122,HNEAP_RS10995,WP_012825053.1,502587315.0,2372669,2373511,842.0,-,nitrate ABC transporter  permease protein,0.5302,26,0.7684735201153036,1850.484236437651,37.0,0.7718946735951898,1858.7223740172171,36.0,nonessential
2123,HNEAP_RS11000,WP_012825054.1,502587316.0,2373514,2374887,1373.0,-,nitrate ABC transporter substrate-binding protein,0.5109,47,0.9997727402189756,2407.452758447293,81.0,0.9996421986600093,2407.138414373302,78.0,nonessential
2124,HNEAP_RS11005,WP_012825055.1,502587317.0,2375195,2376814,1619.0,+,sigma-54-dependent Fis family transcriptional regulator,0.5463,43,0.99529767508042,2396.6768015936514,85.0,0.9883662682646053,2379.9859739811695,80.0,nonessential
2125,HNEAP_RS11010,WP_081441160.1,1174219979.0,2376838,2377326,488.0,-,hypothetical protein,0.5378,9,0.8321148937095144,2003.7326640525107,23.0,0.8651447219154881,2083.2684903724953,23.0,nonessential
2126,HNEAP_RS11015,WP_012825057.1,502587319.0,2377439,2378296,857.0,-,sulfurtransferase,0.542,29,0.9992632723270553,2406.225959763549,53.0,0.9928097570270651,2390.685894921173,47.0,nonessential
2127,HNEAP_RS11020,WP_081441161.1,1174219980.0,2378357,2379850,1493.0,-,hypothetical protein,0.5636,27,0.9999974229390455,2407.9937944372214,96.0,0.9999987258096338,2407.996931749598,95.0,nonessential
2128,HNEAP_RS11025,WP_012825059.1,502587321.0,2379831,2380967,1136.0,-,acyl-CoA dehydrogenase,0.5303,31,0.9999994836629874,2407.9987566604736,80.0,0.9999989000891845,2407.9973514147564,77.0,nonessential
2129,HNEAP_RS11030,WP_012825060.1,502587322.0,2381023,2381502,479.0,-,peroxiredoxin,0.5667,5,0.9999999991010754,2407.9999978353894,49.0,0.9999999990382225,2407.9999976840395,48.0,nonessential
2130,HNEAP_RS11035,WP_012825061.1,502587323.0,2381763,2383055,1292.0,+,IS110 family transposase,0.5754,22,1.5068008946288715e-09,3.6283765542663225e-06,15.0,1.3451253046121718e-09,3.23906173350611e-06,14.0,essential
2131,HNEAP_RS11040,WP_012825062.1,502587324.0,2383653,2384096,443.0,+,cyanase,0.5248,7,0.31621706063592453,761.4506820113063,15.0,0.3629832111156175,874.0635723664069,15.0,nonessential
2132,HNEAP_RS11045,WP_081441162.1,1174219981.0,2384320,2385099,779.0,-,hypothetical protein,0.6154,5,0.9999999373238296,2407.9998490757816,63.0,0.9999999523672597,2407.9998853003613,62.0,nonessential
2133,HNEAP_RS11050,WP_012825064.1,502587326.0,2385048,2387189,2141.0,-,hypothetical protein,0.627,23,0.9996936604630331,2407.2623343949836,117.0,0.9995577733365432,2406.9351181943957,113.0,nonessential
2134,HNEAP_RS11060,WP_012825065.1,502587327.0,2388124,2389149,1025.0,+,2OG-Fe(II) oxygenase,0.5906,24,0.999999984791762,2407.999963378563,79.0,0.9999999911109347,2407.999978595131,78.0,nonessential
2135,HNEAP_RS11065,WP_012825066.1,502587328.0,2389146,2390078,932.0,+,hypothetical protein,0.6152,18,0.9999999999999999,2407.9999999999995,105.0,0.9999999999999999,2407.9999999999995,101.0,nonessential
2136,HNEAP_RS11070,WP_012825067.1,502587329.0,2390123,2392504,2381.0,+,TonB-denpendent receptor,0.5793,52,0.9999999999999999,2407.9999999999995,206.0,0.9999999999999999,2407.9999999999995,197.0,nonessential
2137,HNEAP_RS11075,WP_012825068.1,502587330.0,2392769,2395312,2543.0,+,diguanylate cyclase,0.568,44,0.9999999999998732,2407.999999999695,180.0,0.9999999999999908,2407.9999999999777,180.0,nonessential
2138,HNEAP_RS11080,WP_012825069.1,502587331.0,2395582,2396145,563.0,-,DUF2058 domain-containing protein,0.5337,7,0.9556602131236136,2301.2297932016613,30.0,0.951549116777744,2291.3302732008074,29.0,nonessential
2139,HNEAP_RS11085,WP_012825070.1,502587332.0,2396208,2396753,545.0,-,DUF1415 domain-containing protein,0.5348,12,0.9958209066580574,2397.936743232602,34.0,0.9953865979620089,2396.8909278925175,33.0,nonessential
2140,HNEAP_RS11090,WP_012825071.1,502587333.0,2396921,2397997,1076.0,+,linear amide C-N hydrolase,0.5701,22,0.9122782989079437,2196.766143770328,51.0,0.9564767981326311,2303.1961299033755,52.0,nonessential
2141,HNEAP_RS11095,WP_012825072.1,502587334.0,2398129,2398527,398.0,+,hypothetical protein,0.5213,10,0.3832539424906445,922.8754935174719,14.0,0.4305399497699239,1036.7401990459766,14.0,nonessential
2142,HNEAP_RS11100,WP_012825073.1,502587335.0,2398517,2399242,725.0,-,sulfate transporter CysZ,0.551,13,0.011432027572149875,27.5283223937369,17.0,0.004998848194024834,12.037226451211799,15.0,nonessential
2143,HNEAP_RS12390,WP_012825074.1,502587336.0,2399265,2399891,626.0,-,hypothetical protein,0.5534,15,0.988235085723956,2379.670086423286,36.0,0.9333258626789209,2247.4486773308417,31.0,nonessential
2144,HNEAP_RS11110,WP_012825075.1,502587337.0,2399906,2400850,944.0,-,4-hydroxy-3-methylbut-2-enyl diphosphate reductase,0.5735,12,1.4151612670058436e-10,3.4077083309500714e-07,6.0,3.7977401961443565e-10,9.144958392315611e-07,6.0,essential
2145,HNEAP_RS11115,WP_012825076.1,502587338.0,2400847,2401344,497.0,-,FKBP-type peptidylprolyl isomerase,0.5924,5,0.862689034977286,2077.3551962253046,24.0,0.7180201593859794,1728.9925438014384,21.0,nonessential
2146,HNEAP_RS11120,WP_012825077.1,502587339.0,2401341,2401910,569.0,-,lipoprotein signal peptidase,0.5825,9,2.953807603501601e-08,7.112768709231855e-05,2.0,5.634303158949265e-08,0.0001356740200674983,2.0,essential
2147,HNEAP_RS11125,WP_041600444.1,753844827.0,2401907,2404723,2816.0,-,isoleucine--tRNA ligase,0.612,33,2.0443085536761667e-46,4.922694997252209e-43,2.0,1.1145122614289898e-46,2.6837455255210074e-43,1.0,essential
2148,HNEAP_RS11130,WP_081441163.1,1174219982.0,2404762,2405073,311.0,-,hypothetical protein,0.5577,4,0.9751823743405266,2348.239157411988,19.0,0.9662230001560818,2326.664984375845,18.0,nonessential
2149,HNEAP_RS11135,WP_012825079.1,502587341.0,2405072,2406226,1154.0,+,glycerate kinase,0.6234,12,0.9999999999999999,2407.9999999999995,136.0,0.9999999999999999,2407.9999999999995,134.0,nonessential
2150,HNEAP_RS11140,WP_012825080.1,502587342.0,2406223,2407002,779.0,-,glycosyltransferase family 2 protein,0.6064,6,0.9145214990158939,2202.1677696302722,38.0,0.9155407482616172,2204.6221218139744,37.0,nonessential
2151,HNEAP_RS11145,WP_012825081.1,502587343.0,2406999,2407787,788.0,-,1-acyl-sn-glycerol-3-phosphate acyltransferase,0.597,8,0.7830995127699206,1885.7036267499689,35.0,0.664506453007291,1600.131538841557,32.0,nonessential
2152,HNEAP_RS11150,WP_012825082.1,502587344.0,2407787,2408908,1121.0,-,endoribonuclease L-PSP,0.598,20,0.9999999592806627,2407.9999019478355,83.0,0.9999999946749814,2407.9999871773553,84.0,nonessential
2153,HNEAP_RS11155,WP_012825083.1,502587345.0,2408980,2410314,1334.0,-,NAD(P)/FAD-dependent oxidoreductase,0.573,23,0.9999999998667627,2407.9999996791644,103.0,0.9999999980102832,2407.999995208762,97.0,nonessential
2154,HNEAP_RS11160,WP_012825084.1,502587346.0,2410531,2411259,728.0,+,inositol phosphorylceramide synthase,0.583,12,0.9999999998605649,2407.99999966424,67.0,0.9999999997420512,2407.9999993788592,65.0,nonessential
2155,HNEAP_RS11165,WP_041601094.1,753845477.0,2411330,2412523,1193.0,+,beta-ketoacyl-[acyl-carrier-protein] synthase II,0.6298,12,0.9999999999413024,2407.9999998586563,96.0,0.9999999999948728,2407.9999999876536,97.0,nonessential
2156,HNEAP_RS11170,WP_012825086.1,502587348.0,2412520,2413404,884.0,+,hypothetical protein,0.6316,14,0.9228711722011259,2222.273782660311,43.0,0.8313398678120458,2001.8664016914063,39.0,nonessential
2157,HNEAP_RS11175,WP_012825087.1,502587349.0,2413401,2414123,722.0,+,3-oxoacyl-ACP reductase FabG,0.6473,7,0.9900238320848915,2383.977387660419,41.0,0.9901945177056386,2384.388398635178,40.0,nonessential
2158,HNEAP_RS11180,WP_012825088.1,502587350.0,2414120,2414812,692.0,+,polysaccharide deacetylase family protein,0.6291,10,0.9999939427822127,2407.985414219568,52.0,0.9999945632698517,2407.986908353803,51.0,nonessential
2159,HNEAP_RS11185,WP_012825089.1,502587351.0,2414878,2415558,680.0,-,2OG-Fe(II) oxygenase,0.5932,12,0.8142051410684508,1960.6059796928294,31.0,0.8551838838552609,2059.282792323468,31.0,nonessential
2160,HNEAP_RS11190,WP_012825090.1,502587352.0,2415688,2416593,905.0,-,NAD-dependent epimerase/dehydratase,0.6325,11,0.9999821907629756,2407.957115357245,62.0,0.9999928432263897,2407.9827664891463,62.0,nonessential
2161,HNEAP_RS11195,WP_012825091.1,502587353.0,2416583,2418148,1565.0,-,murein biosynthesis integral membrane protein MurJ,0.5964,26,6.435916923885653e-25,1.5497687952716653e-21,2.0,4.22137654684442e-24,1.0165074724801362e-20,2.0,essential
2162,HNEAP_RS11200,WP_012825092.1,502587355.0,2418177,2419328,1151.0,-,succinyl-diaminopimelate desuccinylase,0.599,13,5.7060461747806025e-21,1.3740159188871691e-17,0.0,2.38269728828066e-20,5.737535070179829e-17,0.0,essential
2163,HNEAP_RS11205,WP_012825093.1,502587356.0,2419349,2419711,362.0,-,arsenate reductase,0.5344,6,0.9118306979914608,2195.6883207634373,19.0,0.8905425196702494,2144.4263873659606,18.0,nonessential
2164,HNEAP_RS11210,WP_012825094.1,502587357.0,2419993,2420331,338.0,+,hypothetical protein,0.5428,4,0.9999996747275812,2407.9992167440155,34.0,0.999999982843147,2407.9999586862978,36.0,nonessential
2165,HNEAP_RS11215,WP_012825095.1,502587358.0,2420860,2421132,272.0,+,PepSY domain-containing protein,0.5751,3,0.9997426410518679,2407.380279652898,23.0,0.9998349931816489,2407.6026635814105,23.0,nonessential
2166,HNEAP_RS11220,WP_081441164.1,1174219983.0,2421136,2421645,509.0,+,hypothetical protein,0.6157,4,0.9920155351618937,2388.77340866984,31.0,0.9749243514931349,2347.617838395469,28.0,nonessential
2167,HNEAP_RS11225,WP_012825097.1,502587360.0,2421695,2422549,854.0,-,nicotinate-nucleotide diphosphorylase (carboxylating),0.6035,10,6.287059437036183e-13,1.5139239124383129e-09,2.0,2.0011735582520702e-11,4.8188259282709853e-08,3.0,essential
2168,HNEAP_RS11230,WP_012825098.1,502587361.0,2422744,2423730,986.0,+,2-hydroxyacid dehydrogenase,0.5826,17,0.9916783579976148,2387.9614860582565,54.0,0.9953350671574719,2396.766841715192,54.0,nonessential
2169,HNEAP_RS11235,WP_012825099.1,502587362.0,2423995,2425116,1121.0,-,flagellar motor protein MotB,0.5267,36,0.9999626832238137,2407.910141202943,72.0,0.9999858110110308,2407.9658329145623,72.0,nonessential
2170,HNEAP_RS11240,WP_012825100.1,502587363.0,2425258,2427249,1991.0,-,hypothetical protein,0.5718,75,0.9999999999983846,2407.99999999611,146.0,0.9999999999986305,2407.999999996702,143.0,nonessential
2171,HNEAP_RS12395,WP_012825101.1,502587364.0,2427636,2427977,341.0,+,IS66 family insertion sequence hypothetical protein,0.6023,5,0.4025370594131049,969.3092390667566,12.0,0.44680902402015676,1075.9161298405375,12.0,nonessential
2172,HNEAP_RS11250,WP_012825102.1,502587365.0,2427974,2428312,338.0,+,IS66 family insertion sequence hypothetical protein,0.5959,7,0.9999569554655514,2407.8963487610476,29.0,0.9999386177332471,2407.852191501659,28.0,nonessential
2173,HNEAP_RS11260,WP_012825103.1,502587366.0,2430091,2430270,179.0,-,hypothetical protein,0.5333,2,0.8982730959441398,2163.0416150334886,10.0,0.9131884285016864,2198.9577358320607,10.0,nonessential
2174,HNEAP_RS11265,WP_012825104.1,502587367.0,2430355,2430567,212.0,-,glycine zipper 2TM domain-containing protein,0.615,2,0.9889299468099468,2381.343311918352,15.0,0.9915425626026615,2387.634490747209,15.0,nonessential
2175,HNEAP_RS11270,WP_041600447.1,753844830.0,2430557,2430820,263.0,+,hypothetical protein,0.4394,8,0.40098228928723806,965.5653526036692,9.0,0.4397491633191114,1058.9159852724204,9.0,nonessential
2176,HNEAP_RS11275,WP_012825105.1,502587368.0,2430909,2431673,764.0,+,Crp/Fnr family transcriptional regulator,0.4797,35,0.04535195199373191,109.20750040090644,21.0,0.06308067529670885,151.89826611447492,21.0,nonessential
2177,HNEAP_RS11280,WP_012825106.1,502587369.0,2431735,2432583,848.0,-,BON domain-containing protein,0.4923,37,0.805101953531234,1938.6855041032115,38.0,0.8873333280991231,2136.6986540626885,39.0,nonessential
2178,HNEAP_RS11285,WP_012825107.1,502587370.0,2432660,2432875,215.0,-,CsbD family protein,0.4537,5,0.9744276743867007,2346.4218399231754,14.0,0.9798201566038599,2359.4069371020946,14.0,nonessential
2179,HNEAP_RS11290,WP_012825108.1,502587371.0,2432878,2433075,197.0,-,hypothetical protein,0.4798,7,0.04482015484149869,107.92693285832885,3.0,0.05271479093504798,126.93721657159554,3.0,nonessential
2180,HNEAP_RS11295,WP_012825110.1,502587373.0,2433455,2434321,866.0,-,glutamate racemase,0.6113,14,0.9999976401155469,2407.994317398237,63.0,0.9999964663093476,2407.991490872909,61.0,nonessential
2181,HNEAP_RS11300,WP_012825111.1,502587374.0,2434506,2435198,692.0,+,phosphate regulon transcriptional regulatory protein PhoB,0.596,8,0.9111559745175145,2194.063586638175,34.0,0.969727172363792,2335.1030310520114,36.0,nonessential
2182,HNEAP_RS11305,WP_012825112.1,502587375.0,2435205,2436623,1418.0,+,phosphate regulon sensor histidine kinase PhoR,0.5863,26,0.466073808164491,1122.3057300600944,55.0,0.3942182358501424,949.2775119271429,52.0,nonessential
2183,HNEAP_RS11310,WP_012825113.1,502587376.0,2436661,2437059,398.0,-,hypothetical protein,0.5388,7,0.9513957341761136,2290.9609278960816,22.0,0.9404123847359775,2264.513022444234,21.0,nonessential
2184,HNEAP_RS11315,WP_012825114.1,502587377.0,2437293,2438774,1481.0,-,sigma-54-dependent Fis family transcriptional regulator,0.6073,10,0.9788957118096135,2357.1808740375495,74.0,0.9886596155536439,2380.6923542531745,74.0,nonessential
2185,HNEAP_RS11320,WP_012825115.1,502587378.0,2438803,2440449,1646.0,-,signal transduction histidine kinase,0.5653,30,0.9868345885062039,2376.297689122939,83.0,0.9833644419830342,2367.941576295146,80.0,nonessential
2186,HNEAP_RS11325,WP_041600448.1,753844831.0,2440486,2440725,239.0,-,hypothetical protein,0.5417,7,0.9924612305648018,2389.8466432000428,17.0,0.9944142662248268,2394.549553069383,17.0,nonessential
2187,HNEAP_RS11330,WP_012825117.1,502587380.0,2441017,2442273,1256.0,-,peptide-methionine (R)-S-oxide reductase,0.5823,23,0.9999998971746074,2407.9997523964544,89.0,0.999999972870541,2407.9999346722625,89.0,nonessential
2188,HNEAP_RS11335,WP_012825118.1,502587381.0,2442486,2443373,887.0,-,glycosyltransferase family 2 protein,0.58,18,0.9999999648548961,2407.99991537059,70.0,0.9999999486435914,2407.999876333768,68.0,nonessential
2189,HNEAP_RS11340,WP_041600449.1,753844832.0,2443461,2444369,908.0,-,hypothetical protein,0.6183,7,0.9999996318713588,2407.999113546232,68.0,0.9999978934539828,2407.9949274371907,64.0,nonessential
2190,HNEAP_RS11345,WP_012825120.1,502587383.0,2444417,2444893,476.0,-,hypothetical protein,0.5912,13,0.9999782297651781,2407.947577274549,38.0,0.9999747589855931,2407.9392196373083,37.0,nonessential
2191,HNEAP_RS11350,WP_041601099.1,753845482.0,2444910,2446169,1259.0,-,MFS transporter,0.5794,22,0.9999999999999999,2407.9999999999995,205.0,0.9999999999999999,2407.9999999999995,201.0,nonessential
2192,HNEAP_RS11355,WP_012825122.1,502587385.0,2446242,2446532,290.0,+,YcgL domain-containing protein,0.567,4,0.9999999999999999,2407.9999999999995,49.0,0.9999999999999999,2407.9999999999995,48.0,nonessential
2193,HNEAP_RS11360,WP_012825123.1,502587386.0,2446603,2447019,416.0,+,hypothetical protein,0.5228,3,0.9999999830175109,2407.9999591061664,42.0,0.9999999792122076,2407.999949942996,41.0,nonessential
2194,HNEAP_RS11365,WP_012825124.1,502587387.0,2447139,2448260,1121.0,+,3-dehydroquinate synthase,0.5838,17,2.1529340417898652e-17,5.1842651726299956e-14,2.0,8.139487219869215e-17,1.9599885225445068e-13,2.0,essential
2195,HNEAP_RS11370,WP_081441165.1,1174219984.0,2448278,2449789,1511.0,+,hypothetical protein,0.5853,19,0.9999999999925631,2407.999999982092,117.0,0.999999999978286,2407.9999999477127,113.0,nonessential
2196,HNEAP_RS11375,WP_012825126.1,502587389.0,2449828,2450541,713.0,-,class I SAM-dependent methyltransferase,0.6261,8,0.9969002411228393,2400.535780623797,43.0,0.9969888084678151,2400.749050790499,42.0,nonessential
2197,HNEAP_RS11380,WP_012825127.1,502587390.0,2450538,2453723,3185.0,-,phosphohydrolase,0.5637,59,0.9999999999999999,2407.9999999999995,260.0,0.9999999999999999,2407.9999999999995,252.0,nonessential
2198,HNEAP_RS11385,WP_012825129.1,502587392.0,2454477,2458937,4460.0,+,glutamate synthase large subunit,0.5846,64,1.7743355822072988e-71,4.272600081955176e-68,4.0,3.975868017139272e-69,9.573890185271367e-66,4.0,essential
2199,HNEAP_RS11395,WP_012825130.1,502587394.0,2460555,2461433,878.0,+,alpha/beta hydrolase,0.4767,19,0.0071692466148063645,17.263545848453724,21.0,0.0035902647095522175,8.645357420601739,19.0,nonessential
2200,HNEAP_RS11400,WP_012825131.1,502587395.0,2461415,2461645,230.0,-,hypothetical protein,0.4805,8,0.18983045140400662,457.11172698084795,6.0,0.21507006572999837,517.8887182778361,6.0,nonessential
2201,HNEAP_RS11405,WP_041600450.1,753844833.0,2461872,2462171,299.0,+,hypothetical protein,0.5333,5,0.9999888275650184,2407.9730967765645,28.0,0.9999827197534908,2407.958389166406,27.0,nonessential
2202,HNEAP_RS11410,WP_049772538.1,908628505.0,2462288,2462554,266.0,-,hypothetical protein,0.5543,7,0.018582517194340818,44.746701403972686,4.0,0.023085256507985704,55.58929767122957,4.0,nonessential
2203,HNEAP_RS12400,WP_012825132.1,502587396.0,2462571,2464172,1601.0,-,hypothetical protein,0.5556,41,0.07556642562250214,181.96395289898516,52.0,0.11592984067966207,279.15905635662625,52.0,nonessential
2204,HNEAP_RS11420,WP_012825133.1,502587397.0,2464176,2465417,1241.0,-,hypothetical protein,0.5443,38,0.9919338558889021,2388.5767249804762,66.0,0.9957911137181725,2397.8650018333597,66.0,nonessential
2205,HNEAP_RS11425,WP_012825134.1,502587398.0,2465554,2466270,716.0,-,hypothetical protein,0.4895,22,0.998829381328245,2405.181150238414,45.0,0.9996466627504984,2407.1491639032,46.0,nonessential
2206,HNEAP_RS11435,WP_012825136.1,502587400.0,2467385,2467840,455.0,-,hypothetical protein,0.5724,13,0.6474649281343922,1559.0955469476164,19.0,0.6084109904749166,1465.0536650635993,18.0,nonessential
2207,HNEAP_RS11440,WP_012825137.1,502587401.0,2467837,2468202,365.0,-,hypothetical protein,0.5792,12,0.009459110122072652,22.777537173950947,6.0,0.012507387863953482,30.117789976399983,6.0,nonessential
2208,HNEAP_RS11445,WP_012825138.1,502587402.0,2468199,2469029,830.0,-,hypothetical protein,0.5716,23,0.83890127496314,2020.0742701112413,38.0,0.8795403297671252,2117.9331140792374,38.0,nonessential
2209,HNEAP_RS11450,WP_012825139.1,502587403.0,2469032,2473048,4016.0,-,hypothetical protein,0.5594,129,0.9999999999999999,2407.9999999999995,270.0,0.9999999999999999,2407.9999999999995,264.0,nonessential
2210,HNEAP_RS11455,WP_041600453.1,753844836.0,2473045,2473686,641.0,-,hypothetical protein,0.5639,14,0.43644755994531675,1050.9657243483227,24.0,0.41637272836097833,1002.6255298932358,23.0,nonessential
2211,HNEAP_RS11460,WP_012825141.1,502587405.0,2474241,2475122,881.0,-,hypothetical protein,0.4921,34,0.13049447960693075,314.23070689348924,28.0,0.1720063764521653,414.19135449681403,28.0,nonessential
2212,HNEAP_RS11465,WP_081441166.1,1174219985.0,2475151,2475912,761.0,-,pilus assembly protein TadE,0.5853,13,0.07135671899967669,171.82697935122147,22.0,0.0963478807582721,232.0056968659192,22.0,nonessential
2213,HNEAP_RS12405,WP_012825143.1,502587407.0,2475952,2477544,1592.0,-,hypothetical protein,0.5562,45,3.933400125569728e-06,0.009471627502371904,31.0,2.4447875741263027e-06,0.005887048478496137,29.0,essential
2214,HNEAP_RS11475,WP_041600454.1,753844837.0,2477553,2478848,1295.0,-,hypothetical protein,0.4645,45,0.9864861369132382,2375.4586176870775,67.0,0.9927339663694223,2390.503391017569,67.0,nonessential
2215,HNEAP_RS11480,WP_012825145.1,502587409.0,2478881,2479675,794.0,-,pilus assembly protein TadE,0.5748,18,0.09754291554339467,234.88334062849435,24.0,0.12965159730886106,312.20104631973743,24.0,nonessential
2216,HNEAP_RS11485,WP_012825146.1,502587410.0,2479675,2480217,542.0,-,tetratricopeptide repeat protein,0.5506,13,0.6789400963106712,1634.8877519160962,23.0,0.6534975776257013,1573.6221669226886,22.0,nonessential
2217,HNEAP_RS11490,WP_012825147.1,502587411.0,2480202,2480555,353.0,-,hypothetical protein,0.5678,4,0.955241185140131,2300.2207738174357,20.0,0.9427580960596854,2270.1614953117223,19.0,nonessential
2218,HNEAP_RS11495,WP_012825148.1,502587412.0,2480552,2481448,896.0,-,type II secretion protein F,0.5452,21,0.9756650935763175,2349.4015453317725,47.0,0.9777137255250601,2354.3346510643446,46.0,nonessential
2219,HNEAP_RS11500,WP_012825149.1,502587413.0,2481445,2482299,854.0,-,type II secretion protein F,0.5462,17,0.8375716374766701,2016.8725030438216,39.0,0.8789575847147368,2116.529863993086,39.0,nonessential
2220,HNEAP_RS11505,WP_012825150.1,502587414.0,2482296,2484002,1706.0,-,hypothetical protein,0.5542,29,0.907388705969391,2184.9920039742938,78.0,0.9111233885731385,2193.9851196841173,76.0,nonessential
2221,HNEAP_RS11510,WP_012825151.1,502587415.0,2484019,2485350,1331.0,-,type II and III secretion system protein,0.5263,29,0.999999803731878,2407.9995273863624,92.0,0.9999999021191657,2407.999764302951,91.0,nonessential
2222,HNEAP_RS11515,WP_012825152.1,502587416.0,2485375,2486151,776.0,-,Flp pilus assembly protein CpaB,0.5212,19,0.9999976175283742,2407.994263008325,58.0,0.999996020651513,2407.9904177288436,56.0,nonessential
2223,HNEAP_RS11520,WP_012825153.1,502587417.0,2486174,2486377,203.0,-,hypothetical protein,0.5147,5,0.5844796216291094,1407.4269288828955,8.0,0.6189455058545698,1490.420778097804,8.0,nonessential
2224,HNEAP_RS11525,WP_012825154.1,502587418.0,2486385,2487077,692.0,-,hypothetical protein,0.5051,15,0.5910483914170437,1423.2445265322413,28.0,0.501246724567716,1207.00211275906,26.0,nonessential
2225,HNEAP_RS11530,WP_012825155.1,502587419.0,2487079,2487954,875.0,-,hypothetical protein,0.5274,25,0.9998631171979534,2407.670386212672,57.0,0.9998880408616027,2407.730402394739,56.0,nonessential
2226,HNEAP_RS11535,WP_012825156.1,502587420.0,2487962,2488456,494.0,-,hypothetical protein,0.4485,18,0.0008533692849328249,2.0549132381182424,7.0,0.001279918921795351,3.0820447636832053,7.0,nonessential
2227,HNEAP_RS11540,WP_012825157.1,502587421.0,2488472,2489026,554.0,-,hypothetical protein,0.409,21,0.16440374698311996,395.88422273535286,17.0,0.20161256328943394,485.4830524009569,17.0,nonessential
2228,HNEAP_RS11545,WP_041600455.1,753844838.0,2489070,2489651,581.0,-,hypothetical protein,0.4399,22,0.9892933765302739,2382.2184506849,34.0,0.9959358063457245,2398.213421680505,35.0,nonessential
2229,HNEAP_RS11550,WP_081441167.1,1174219986.0,2489623,2491278,1655.0,-,hypothetical protein,0.5266,60,0.9999999641651067,2407.999913709577,112.0,0.9999999862405121,2407.999966867153,111.0,nonessential
2230,HNEAP_RS11555,WP_012825160.1,502587424.0,2491384,2491662,278.0,-,hypothetical protein,0.5233,8,0.9099351667812419,2191.1238816092305,15.0,0.9264510303419353,2230.8940810633803,15.0,nonessential
2231,HNEAP_RS11560,WP_012825161.1,502587425.0,2492137,2493132,995.0,+,OmpA/MotB domain-containing protein,0.5392,34,0.9971760425986704,2401.1999105775985,57.0,0.9985367366608772,2404.476461879392,57.0,nonessential
2232,HNEAP_RS11565,WP_012825162.1,502587426.0,2493233,2493859,626.0,+,non-canonical purine NTP pyrophosphatase,0.5726,15,0.5655058266566064,1361.7380305891083,25.0,0.6256601226398104,1506.5895753166635,25.0,nonessential
2233,HNEAP_RS11570,WP_041601107.1,753845490.0,2493865,2495025,1160.0,+,YggW family oxidoreductase,0.5616,19,0.8349023919482387,2010.4449598113588,52.0,0.8827338631509637,2125.6231424675207,52.0,nonessential
2234,HNEAP_RS11575,WP_012825164.1,502587428.0,2495044,2496432,1388.0,-,UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase,0.5745,29,3.8726180598385286e-25,9.325264288091177e-22,0.0,2.1704621104363294e-24,5.226472761930681e-21,0.0,essential
2235,HNEAP_RS11580,WP_012825165.1,502587429.0,2496553,2496999,446.0,-,ATP synthase F1 subunit epsilon,0.5481,9,2.7818390233313804e-07,0.0006698668368181964,1.0,4.6966002354102616e-07,0.001130941336686791,1.0,essential
2236,HNEAP_RS11585,WP_012825166.1,502587430.0,2497014,2498402,1388.0,-,F0F1 ATP synthase subunit beta,0.5529,37,2.2602309873588873e-23,5.442636217560201e-20,1.0,1.2278456798158899e-22,2.9566523969966627e-19,1.0,essential
2237,HNEAP_RS11590,WP_012825167.1,502587431.0,2498444,2499304,860.0,-,F0F1 ATP synthase subunit gamma,0.5261,20,7.488797947679144e-16,1.8033025458011378e-12,0.0,2.178760945105808e-15,5.246456355814786e-12,0.0,essential
2238,HNEAP_RS11595,WP_012825168.1,502587432.0,2499320,2500858,1538.0,-,F0F1 ATP synthase subunit alpha,0.5322,37,8.90883125090355e-28,2.145246565217575e-24,0.0,6.015381590637346e-27,1.448503887025473e-23,0.0,essential
2239,HNEAP_RS11600,WP_012825169.1,502587433.0,2500868,2501404,536.0,-,F0F1 ATP synthase subunit delta,0.527,14,3.740153358841816e-10,9.006289288091093e-07,0.0,7.277025200624173e-10,1.752307668310301e-06,0.0,essential
2240,HNEAP_RS11605,WP_012825170.1,502587434.0,2501423,2501893,470.0,-,F0F1 ATP synthase subunit B,0.5287,5,5.416145726588819e-09,1.3042078909625875e-05,0.0,9.708699306712034e-09,2.3378547930562578e-05,0.0,essential
2241,HNEAP_RS11610,WP_012825171.1,502587435.0,2501985,2502272,287.0,-,F0F1 ATP synthase subunit C,0.5278,2,8.959313636713799e-06,0.021574027237206826,0.0,1.2795393982395699e-05,0.030811308709608843,0.0,essential
2242,HNEAP_RS11615,WP_012825172.1,502587436.0,2502322,2503143,821.0,-,F0F1 ATP synthase subunit A,0.5182,14,3.633623586670228e-15,8.749765596701909e-12,0.0,1.0071745164074539e-14,2.425276235509149e-11,0.0,essential
2243,HNEAP_RS11620,WP_012825173.1,502587437.0,2503183,2503590,407.0,-,hypothetical protein,0.5735,13,6.945885072059112e-08,0.00016725691253518342,0.0,1.1513899692697149e-07,0.0002772547046001474,0.0,essential
2244,HNEAP_RS11625,WP_012825174.1,502587438.0,2503574,2503840,266.0,-,hypothetical protein,0.5618,6,2.0971065216465772e-05,0.05049832504124958,0.0,2.9179250102531387e-05,0.07026363424689558,0.0,ambiguous
2245,HNEAP_RS11630,WP_012825175.1,502587439.0,2503955,2504815,860.0,-,chromosome partitioning protein ParB,0.5854,12,0.9999999999328958,2407.9999998384133,76.0,0.9999999999934054,2407.99999998412,77.0,nonessential
2246,HNEAP_RS11635,WP_012825176.1,502587440.0,2504853,2505632,779.0,-,ParA family protein,0.5974,13,0.9999999999897292,2407.999999975268,73.0,0.9999999999826374,2407.999999958191,71.0,nonessential
2247,HNEAP_RS11640,WP_081441168.1,1174219987.0,2505629,2506309,680.0,-,16S rRNA (guanine(527)-N(7))-methyltransferase RsmG,0.5536,19,0.999882726629733,2407.717605724397,47.0,0.9997890180578248,2407.4919554832422,45.0,nonessential
2248,HNEAP_RS11645,WP_012825178.1,502587442.0,2506306,2508186,1880.0,-,tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG,0.596,36,0.9999999999999788,2407.999999999949,146.0,0.9999999999999606,2407.999999999905,142.0,nonessential
2249,HNEAP_RS11650,WP_012825179.1,502587443.0,2508604,2509035,431.0,+,cold-shock protein,0.5347,9,0.9999999999777625,2407.999999946452,49.0,0.9999999999923472,2407.9999999815723,49.0,nonessential
2250,HNEAP_RS11655,WP_012825180.1,502587444.0,2509042,2509968,926.0,-,LysR family transcriptional regulator,0.5685,18,0.9999999991592879,2407.9999979755653,77.0,0.9999999725983272,2407.999934016772,71.0,nonessential
2251,HNEAP_RS11660,WP_012825181.1,502587446.0,2510121,2510447,326.0,+,thioredoxin TrxA,0.4985,7,0.010052639937439376,24.206756969354018,5.0,0.0002739353064173753,0.6596362178530397,2.0,nonessential
2252,HNEAP_RS11665,WP_012825182.1,502587447.0,2510632,2511891,1259.0,+,transcription termination factor Rho,0.5635,18,7.191886906997976e-23,1.7318063672051124e-19,0.0,3.4341619463156657e-22,8.269461966728123e-19,0.0,essential
2253,HNEAP_RS11670,WP_012825183.1,502587449.0,2512118,2513404,1286.0,-,phosphoribosylamine--glycine ligase,0.5897,22,1.3048458127231591e-21,3.1420687170373672e-18,1.0,6.2454007177589025e-21,1.5038924928363436e-17,1.0,essential
2254,HNEAP_RS11675,WP_012825184.1,502587450.0,2513479,2513958,479.0,+,tRNA (uridine(34)/cytosine(34)/5-carboxymethylaminomethyluridine(34)-2'-O)-methyltransferase TrmL,0.5563,10,0.016560959261284206,39.87878990117237,10.0,0.022416767299323792,53.979575656771694,10.0,nonessential
2255,HNEAP_RS11680,WP_012825185.1,502587451.0,2513955,2514650,695.0,+,tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO,0.5776,10,0.9998061623899717,2407.533239035052,47.0,0.9999499780625097,2407.8795471745234,48.0,nonessential
2256,HNEAP_RS11685,WP_012825186.1,502587452.0,2514663,2515667,1004.0,-,glycerol-3-phosphate dehydrogenase,0.606,16,1.982493595123329e-15,4.7738445770569764e-12,2.0,6.482619273469875e-15,1.561014721051546e-11,2.0,essential
2257,HNEAP_RS11690,WP_012825187.1,502587453.0,2515677,2516171,494.0,-,protein-export chaperone SecB,0.5253,11,0.8173769597039431,1968.243718967095,23.0,0.7272793150173563,1751.288590561794,21.0,nonessential
2258,HNEAP_RS11695,WP_012825188.1,502587454.0,2516348,2516791,443.0,-,thioredoxin TrxC,0.5653,3,0.9980772383990307,2403.369990064866,30.0,0.9987931291589155,2405.0938550146684,30.0,nonessential
2259,HNEAP_RS11700,WP_049772599.1,908628566.0,2516815,2517114,299.0,-,glutaredoxin 3,0.5367,3,0.35727481530397903,860.3177552519815,10.0,0.39723457647963206,956.540860162954,10.0,nonessential
2260,HNEAP_RS11705,WP_049772540.1,908628507.0,2517179,2517607,428.0,-,rhodanese-like domain-containing protein,0.5478,7,0.9409685525887274,2265.8522746336553,23.0,0.9296199220559744,2238.5247723107864,22.0,nonessential
2261,HNEAP_RS11710,WP_012825191.1,502587457.0,2517655,2517867,212.0,-,DUF2892 domain-containing protein,0.5258,4,0.6656827958467952,1602.9641723990828,9.0,0.6985753828764237,1682.1695219664284,9.0,nonessential
2262,HNEAP_RS11715,WP_081441195.1,1174220014.0,2517928,2518245,317.0,-,ArsR family transcriptional regulator,0.5472,7,0.9162739048286005,2206.38756282727,17.0,0.9328162372951108,2246.2214994066267,17.0,nonessential
2263,HNEAP_RS11720,WP_041600458.1,753844841.0,2518453,2519496,1043.0,+,hypothetical protein,0.5402,26,1.592403425630011e-10,3.834507448917067e-07,8.0,1.962242305011391e-12,4.725079470467429e-09,5.0,essential
2264,HNEAP_RS11725,WP_081441169.1,1174219988.0,2519406,2519726,320.0,+,M23 family peptidase,0.5639,7,0.1811330590497758,436.16840619186013,9.0,0.07256129382011745,174.7275955188428,7.0,nonessential
2265,HNEAP_RS11730,WP_041600460.1,753844843.0,2519728,2519928,200.0,+,hypothetical protein,0.4776,6,0.970492894952637,2336.94689104595,13.0,0.9763933940405761,2351.155292849707,13.0,nonessential
2266,HNEAP_RS11735,WP_012825193.1,502587459.0,2519937,2521277,1340.0,+,S41 family peptidase,0.5541,19,0.03380725788589686,81.40787698923964,40.0,0.027457770470532362,66.11831129304193,38.0,nonessential
2267,HNEAP_RS11740,WP_012825194.1,502587460.0,2521431,2521985,554.0,+,DJ-1 family protein,0.5694,10,0.9994988929409725,2406.793334201862,38.0,0.998115359103311,2403.461784720773,35.0,nonessential
2268,HNEAP_RS11745,WP_012825196.1,502587462.0,2522157,2523464,1307.0,-,ammonium transporter,0.5612,34,0.9999999999999999,2407.9999999999995,120.0,0.9999999999999999,2407.9999999999995,116.0,nonessential
2269,HNEAP_RS11750,WP_012825197.1,502587463.0,2523477,2523815,338.0,-,nitrogen regulatory protein P-II 1,0.5162,9,0.415273541659708,999.9786883165768,12.0,0.4596634536913479,1106.8695964887659,12.0,nonessential
2270,HNEAP_RS11755,WP_012825198.1,502587464.0,2523844,2524623,779.0,-,hypothetical protein,0.4949,36,0.9999999718730991,2407.9999322704225,64.0,0.9999999523672597,2407.9998853003613,62.0,nonessential
2271,HNEAP_RS11760,WP_012825199.1,502587465.0,2524987,2526063,1076.0,-,cell division protein ZapE,0.5645,25,0.9972976632809336,2401.4927731804883,61.0,0.9978668591107385,2402.863396738658,60.0,nonessential
2272,HNEAP_RS11765,WP_012825200.1,502587466.0,2526147,2526395,248.0,-,succinate dehydrogenase assembly factor 2,0.5703,3,0.02998022433373288,72.19238019562877,4.0,0.03646210598870734,87.80075122080727,4.0,nonessential
2273,HNEAP_RS11770,WP_012825201.1,502587467.0,2526392,2527090,698.0,-,succinate dehydrogenase iron-sulfur subunit,0.5751,15,0.99999822071484,2407.9957154813346,54.0,0.9999984428700475,2407.9962504310743,53.0,nonessential
2274,HNEAP_RS11775,WP_012825202.1,502587468.0,2527103,2528890,1787.0,-,succinate dehydrogenase flavoprotein subunit,0.6007,30,0.9999998179026027,2407.999561509467,116.0,0.9999997893836307,2407.999492835783,113.0,nonessential
2275,HNEAP_RS11780,WP_012825203.1,502587469.0,2528887,2529237,350.0,-,succinate dehydrogenase  hydrophobic membrane anchor protein,0.5499,11,0.9999946771110031,2407.9871824832953,32.0,0.9999971709841142,2407.993187729747,32.0,nonessential
2276,HNEAP_RS11785,WP_012825204.1,502587470.0,2529231,2529605,374.0,-,succinate dehydrogenase  cytochrome b556 subunit,0.584,5,0.2758500223599333,664.2468538427194,12.0,0.3161420620810513,761.2700854911715,12.0,nonessential
2277,HNEAP_RS11790,WP_041601111.1,753845494.0,2529705,2530448,743.0,-,GntR family transcriptional regulator,0.5739,14,0.9991689416657573,2405.9988115311435,47.0,0.9938747979379363,2393.2505134345506,42.0,nonessential
2278,HNEAP_RS11795,WP_012825206.1,502587472.0,2530555,2531109,554.0,-,aldehyde dehydrogenase,0.5946,6,0.9438791435697833,2272.860977716038,29.0,0.9097745384712781,2190.7370886388376,27.0,nonessential
2279,HNEAP_RS11800,WP_049772541.1,908628508.0,2531230,2532708,1478.0,+,aspartate aminotransferase family protein,0.6099,21,0.9999916077391607,2407.979791435899,93.0,0.999997457064504,2407.993876611326,93.0,nonessential
2280,HNEAP_RS11805,WP_012825208.1,502587474.0,2532705,2534219,1514.0,+,methylmalonate-semialdehyde dehydrogenase (CoA acylating),0.6178,18,0.9999999097987388,2407.999782795363,103.0,0.9999999610021897,2407.999906093273,102.0,nonessential
2281,HNEAP_RS11810,WP_012825209.1,502587475.0,2534387,2534908,521.0,+,membrane protein,0.5977,9,0.9988922020190351,2405.3324224618364,35.0,0.9987566048372885,2405.0059044481904,34.0,nonessential
2282,HNEAP_RS11815,WP_012825210.1,502587476.0,2534974,2536332,1358.0,-,type III glutamate--ammonia ligase,0.6277,18,0.9998382220483037,2407.6104386923153,81.0,0.9995923491113606,2407.0183766601563,77.0,nonessential
2283,HNEAP_RS11820,WP_012825211.1,502587477.0,2536335,2537657,1322.0,-,4-aminobutyrate--2-oxoglutarate transaminase,0.6017,19,0.999999999653119,2407.9999991647105,101.0,0.9999999999318481,2407.9999998358903,101.0,nonessential
2284,HNEAP_RS11825,WP_012825212.1,502587478.0,2537681,2539168,1487.0,-,gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase,0.6263,17,0.9968158695921204,2400.332613977826,80.0,0.997870102791355,2402.871207521583,79.0,nonessential
2285,HNEAP_RS11830,WP_012825213.1,502587479.0,2539258,2540718,1460.0,-,NAD-dependent succinate-semialdehyde dehydrogenase,0.6208,22,0.999996957050792,2407.992672578307,94.0,0.9999973130989658,2407.9935299423096,92.0,nonessential
2286,HNEAP_RS11835,WP_012825214.1,502587480.0,2540868,2541701,833.0,-,putrescine ABC transporter permease PotI,0.5743,12,0.9952451556740673,2396.550334863154,48.0,0.9894566121845949,2382.6115221405043,45.0,nonessential
2287,HNEAP_RS11840,WP_012825215.1,502587481.0,2541698,2542612,914.0,-,putrescine ABC transporter permease,0.5585,19,0.9999999999635769,2407.9999999122933,80.0,0.9999999999792936,2407.9999999501388,79.0,nonessential
2288,HNEAP_RS11845,WP_012825216.1,502587482.0,2542627,2543739,1112.0,-,polyamine ABC transporter ATP-binding protein,0.5553,19,0.9999999966583052,2407.999991953199,86.0,0.999999996309959,2407.9999911143814,84.0,nonessential
2289,HNEAP_RS11850,WP_012825217.1,502587483.0,2543860,2544978,1118.0,-,polyamine ABC transporter substrate-binding protein,0.5317,26,0.9982287054598593,2403.734722747341,64.0,0.9978977437499349,2402.937766949843,62.0,nonessential
2290,HNEAP_RS11855,WP_012825219.1,502587485.0,2545123,2546538,1415.0,-,aspartate aminotransferase family protein,0.5671,26,0.99999999998902,2407.99999997356,111.0,0.9999999999826557,2407.9999999582346,108.0,nonessential
2291,HNEAP_RS11860,WP_012825220.1,502587486.0,2546579,2547949,1370.0,-,glutamine synthetase,0.574,28,0.998795493979951,2405.0995495037223,77.0,0.9972594334627909,2401.4007157784004,73.0,nonessential
2292,HNEAP_RS11865,WP_012825221.1,502587487.0,2547975,2548742,767.0,-,gamma-glutamyl-gamma-aminobutyrate hydrolase,0.5977,13,0.9999069652010492,2407.7759722041264,52.0,0.9997240345482846,2407.3354751922693,49.0,nonessential
2293,HNEAP_RS11870,WP_012825222.1,502587489.0,2548991,2550502,1511.0,+,PLP-dependent aminotransferase family protein,0.586,32,0.9999999869379278,2407.99996854653,106.0,0.9999999899277244,2407.9999757459605,104.0,nonessential
2294,HNEAP_RS11875,WP_012825223.1,502587490.0,2550534,2551841,1307.0,-,FAD-binding oxidoreductase,0.5986,24,0.999952922988665,2407.8866385567053,81.0,0.999951849226025,2407.8840529362683,79.0,nonessential
2295,HNEAP_RS11880,WP_012825224.1,502587491.0,2551855,2552805,950.0,-,agmatinase,0.6067,14,0.9999999997695979,2407.999999445192,80.0,0.9999999993051221,2407.999998326734,77.0,nonessential
2296,HNEAP_RS11885,WP_012825225.1,502587492.0,2553183,2554571,1388.0,+,aspartate aminotransferase family protein,0.6228,25,0.9999938302532926,2407.9851432499286,89.0,0.9999231214126147,2407.8148763615764,82.0,nonessential
2297,HNEAP_RS11890,WP_012825226.1,502587493.0,2554627,2555805,1178.0,-,MFS transporter,0.5895,22,0.9999394283644519,2407.8541435016004,74.0,0.999202908429107,2406.0806034972898,67.0,nonessential
2298,HNEAP_RS11895,WP_012825227.1,502587494.0,2555971,2556345,374.0,-,RidA family protein,0.584,6,0.9275185927767171,2233.464771406335,20.0,0.9434073715678021,2271.7249507352676,20.0,nonessential
2299,HNEAP_RS11900,WP_012825228.1,502587495.0,2556342,2557445,1103.0,-,alanine racemase,0.606,18,0.9998864255229098,2407.726512659167,69.0,0.9996247302359202,2407.096350408096,65.0,nonessential
2300,HNEAP_RS11905,WP_012825229.1,502587496.0,2557465,2558784,1319.0,-,D-amino acid dehydrogenase small subunit,0.5879,23,0.9999985329068607,2407.9964672397205,88.0,0.9999995698720598,2407.99896425192,88.0,nonessential
2301,HNEAP_RS11910,WP_012825230.1,502587497.0,2558950,2559450,500.0,+,AsnC family transcriptional regulator,0.5449,7,0.8990919296669616,2165.0133666380434,25.0,0.9222963995852502,2220.8897302012824,25.0,nonessential
2302,HNEAP_RS11915,WP_012825231.1,502587498.0,2559570,2561102,1532.0,+,hypothetical protein,0.5114,48,0.9999956409130814,2407.9895033187,97.0,0.9999895372865873,2407.9748057861025,93.0,nonessential
2303,HNEAP_RS11920,WP_012825232.1,502587499.0,2561274,2561537,263.0,+,hypothetical protein,0.5038,5,0.10017262928103805,241.21569130873962,6.0,0.11768772024895029,283.3920303594723,6.0,nonessential
2304,HNEAP_RS11925,WP_012825233.1,502587500.0,2561751,2563262,1511.0,+,ATP-dependent protease,0.5456,26,0.00014974819632427693,0.36059365674885885,34.0,0.00034410315470597937,0.8286003965319984,34.0,nonessential
2305,HNEAP_RS11930,WP_012825234.1,502587501.0,2563249,2564277,1028.0,-,tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic acid(34) synthase CmoB,0.5481,16,0.9999999999670414,2407.9999999206357,87.0,0.9999999999110762,2407.9999997858718,84.0,nonessential
2306,HNEAP_RS11935,WP_012825235.1,502587502.0,2564283,2565059,776.0,-,carboxy-S-adenosyl-L-methionine synthase CmoA,0.5071,9,0.999999879984915,2407.999711003675,62.0,0.9999999074097474,2407.9997770426717,61.0,nonessential
2307,HNEAP_RS11940,WP_012825236.1,502587503.0,2565056,2566168,1112.0,-,tRNA 2-selenouridine(34) synthase MnmH,0.5112,25,0.6494528446174752,1563.8824498388803,46.0,0.6698340496643009,1612.9603915916366,45.0,nonessential
2308,HNEAP_RS11945,WP_012825237.1,502587504.0,2566168,2567229,1061.0,-,selenide  water dikinase SelD,0.5141,24,0.012440921868982019,29.957739860508703,28.0,0.030350567244144325,73.08416592389953,29.0,nonessential
2309,HNEAP_RS11950,WP_012825238.1,502587505.0,2567548,2568528,980.0,-,cytochrome oxidase assembly,0.5637,17,0.9999992739131842,2407.9982515829474,71.0,0.999999515637863,2407.998833655974,70.0,nonessential
2310,HNEAP_RS11955,WP_012825239.1,502587506.0,2568631,2569641,1010.0,-,lanthionine synthetase C,0.5717,15,0.9999999647783233,2407.9999151862025,77.0,0.9999999899266555,2407.9999757433866,77.0,nonessential
2311,HNEAP_RS11960,WP_012825240.1,502587507.0,2569729,2570364,635.0,-,SCO family protein,0.5079,25,0.6884074649416658,1657.6851755795312,27.0,0.7419767848135849,1786.6800978311123,27.0,nonessential
2312,HNEAP_RS11965,WP_081441196.1,1174220015.0,2570374,2571273,899.0,-,cytochrome c oxidase assembly protein,0.56,24,0.9823590716439449,2365.520644518619,48.0,0.9892833627254944,2382.1943374429907,48.0,nonessential
2313,HNEAP_RS11970,WP_012825242.1,502587509.0,2571391,2572311,920.0,-,protoheme IX farnesyltransferase,0.57,30,0.2534370563326633,610.2764316490532,32.0,0.08340216351226565,200.83240973753567,27.0,nonessential
2314,HNEAP_RS11975,WP_012825243.1,502587510.0,2572372,2572971,599.0,-,hypothetical protein,0.5483,7,0.9999999205380019,2407.999808655509,52.0,0.9999999254543254,2407.9998204940157,51.0,nonessential
2315,HNEAP_RS11980,WP_012825244.1,502587511.0,2572959,2573702,743.0,-,SURF1 family protein,0.5672,14,0.9960557512546976,2398.502249021312,44.0,0.9658915155433644,2325.8667694284213,38.0,nonessential
2316,HNEAP_RS11985,WP_012825245.1,502587512.0,2573878,2575530,1652.0,-,cytochrome c oxidase subunit I,0.5566,32,0.8690007716582108,2092.5538581529713,74.0,0.8954973258319052,2156.3575606032277,73.0,nonessential
2317,HNEAP_RS11990,WP_012825246.1,502587513.0,2575527,2576660,1133.0,-,cytochrome c oxidase subunit II,0.5538,27,0.9999901982663781,2407.9763974254383,75.0,0.9999937147570735,2407.984865135033,74.0,nonessential
2318,HNEAP_RS11995,WP_041600462.1,753844845.0,2577455,2577844,389.0,+,DUF2173 domain-containing protein,0.4462,14,0.9999999997665582,2407.9999994378722,44.0,0.999999999705745,2407.999999291434,43.0,nonessential
2319,HNEAP_RS12000,WP_081441170.1,1174219989.0,2577872,2578270,398.0,+,DUF2173 domain-containing protein,0.5213,9,0.022530677940511824,54.25387248075247,8.0,0.013569709364964185,32.675860150833756,7.0,nonessential
2320,HNEAP_RS12410,WP_012825249.1,502587516.0,2578280,2578618,338.0,+,DUF2173 domain-containing protein,0.5074,8,0.5266360501778349,1268.1396088282263,13.0,0.5717788155989436,1376.8433879622562,13.0,nonessential
2321,HNEAP_RS12010,WP_012825250.1,502587517.0,2578715,2580061,1346.0,-,tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE,0.5538,20,0.0002816651218020107,0.6782496132992418,30.0,0.0005980628586075028,1.4401353635268668,30.0,nonessential
2322,HNEAP_RS12015,WP_012825251.1,502587518.0,2580078,2581790,1712.0,-,membrane protein insertase YidC,0.5289,42,5.563899689539695e-29,1.3397870452411585e-25,1.0,4.519167659116313e-28,1.0882155723152083e-24,1.0,essential
2323,HNEAP_RS12600,WP_012825252.1,502587519.0,2581804,2582214,410.0,-,membrane protein insertion efficiency factor YidD,0.5474,8,5.942854695145844e-05,0.14310394105911192,3.0,1.5537569859125475e-05,0.03741446822077414,2.0,ambiguous
2324,HNEAP_RS12025,WP_012825253.1,502587520.0,2582199,2582570,371.0,-,ribonuclease P protein component,0.5188,9,2.9846385027129754e-07,0.0007187009514532845,0.0,4.7312054556039764e-07,0.0011392742737094375,0.0,essential
2325,HNEAP_RS12030,WP_012825254.1,502587521.0,2582595,2582729,134.0,-,50S ribosomal protein L34,0.5556,4,0.0043976671203713735,10.589582425854267,0.0,0.00519383883973908,12.506763926091704,0.0,ambiguous
2326,GFF94,,,94056,94408,352.0,+,hypothetical protein,0.5354,11,0.9959129852223912,2398.158468415518,24.0,0.998648751865679,2404.746194492555,25.0,nonessential
2327,HNEAP_RS00520,,,104152,104227,75.0,-,tRNA-Phe,0.5526,2,0.19663287202442295,473.4919558348105,1.0,0.21072343573728922,507.4220332553924,1.0,nonessential
2328,HNEAP_RS00795,,,167157,167233,76.0,+,tRNA-Pro,0.5714,5,0.9185389016116547,2211.8416750808647,5.0,0.9273033119741799,2232.946375233825,5.0,nonessential
2329,GFF160,,,168060,169853,1793.0,+,2-isopropylmalate synthase,0.5541,35,0.9999989538838921,2407.9974809524124,113.0,0.9999979623513361,2407.9950933420173,109.0,nonessential
2330,HNEAP_RS01510,,,319074,319149,75.0,+,tRNA-Thr,0.5658,3,0.047963187029568956,115.49535436720204,0.0,0.05264480080801909,126.76868034570997,0.0,ambiguous
2331,HNEAP_RS01515,,,319250,319334,84.0,+,tRNA-Tyr,0.5765,1,0.03331324947128111,80.2183047268449,0.0,0.03697584820063623,89.03784246713204,0.0,ambiguous
2332,HNEAP_RS01520,,,319388,319461,73.0,+,tRNA-Gly,0.5405,2,0.05200963655389077,125.23920482176898,0.0,0.05694461667234833,137.1226369470148,0.0,ambiguous
2333,HNEAP_RS01525,,,319485,319560,75.0,+,tRNA-Thr,0.5789,2,0.047963187029568956,115.49535436720204,0.0,0.05264480080801909,126.76868034570997,0.0,ambiguous
2334,HNEAP_RS01535,,,320906,320981,75.0,+,tRNA-Trp,0.5658,2,0.047963187029568956,115.49535436720204,0.0,0.05264480080801909,126.76868034570997,0.0,ambiguous
2335,HNEAP_RS01790,,,365792,365881,89.0,+,tRNA-Ser,0.5667,4,0.027206804295101042,65.51398474260331,0.0,0.03038611503541589,73.16976500528146,0.0,ambiguous
2336,GFF365,,,376812,377594,782.0,+,IS66 family transposase,0.5824,13,0.9905327981677929,2385.2029779880454,44.0,0.9790231585653819,2357.4877658254395,41.0,nonessential
2337,GFF366,,,377632,378186,554.0,+,IS66 family transposase,0.573,8,0.9909308849379622,2386.161570930613,33.0,0.9941200112383146,2393.8409870618616,33.0,nonessential
2338,GFF371,,,388487,388765,278.0,-,Killer protein,0.4982,10,0.9465505183879896,2279.293648278279,16.0,0.9264510303419353,2230.8940810633803,15.0,nonessential
2339,HNEAP_RS01915,,,398461,398544,83.0,+,tRNA-Leu,0.5476,3,0.03469004713959759,83.533633512151,0.0,0.03845623284620934,92.60260869367208,0.0,ambiguous
2340,GFF455,,,483774,484823,1049.0,-,integrase,0.54,28,0.8242881362168399,1984.8858320101506,47.0,0.7966779401558997,1918.4004798954063,45.0,nonessential
2341,HNEAP_RS02290,,,484996,485072,76.0,-,tRNA-Met,0.5455,3,0.04605959768587042,110.91151122757596,0.0,0.050618222825274,121.8886805632598,0.0,ambiguous
2342,HNEAP_RS02375,,,503998,504073,75.0,+,tRNA-Gly,0.5921,1,0.047963187029568956,115.49535436720204,0.0,0.05264480080801909,126.76868034570997,0.0,ambiguous
2343,HNEAP_RS02380,,,504075,504150,75.0,+,tRNA-Val,0.5921,3,0.047963187029568956,115.49535436720204,0.0,0.05264480080801909,126.76868034570997,0.0,ambiguous
2344,HNEAP_RS02385,,,504161,504237,76.0,+,tRNA-Asp,0.6623,2,0.04605959768587042,110.91151122757596,0.0,0.050618222825274,121.8886805632598,0.0,ambiguous
2345,GFF511,,,546235,546670,435.0,+,pilus assembly protein PilG,0.5321,11,0.538064162498782,1295.658503297067,17.0,0.5890128965211034,1418.343054822817,17.0,nonessential
2346,HNEAP_RS02700,,,573351,573426,75.0,+,tRNA-Lys,0.5263,2,0.19663287202442295,473.4919558348105,1.0,0.21072343573728922,507.4220332553924,1.0,nonessential
2347,HNEAP_RS02705,,,573784,575321,1537.0,+,16S ribosomal RNA,0.5371,62,9.277022834983125e-28,2.2339070986639366e-24,0.0,6.2562165944950656e-27,1.5064969559544117e-23,0.0,essential
2348,HNEAP_RS02710,,,575391,575467,76.0,+,tRNA-Ile,0.5974,2,0.04605959768587042,110.91151122757596,0.0,0.050618222825274,121.8886805632598,0.0,ambiguous
2349,HNEAP_RS02715,,,575749,575824,75.0,+,tRNA-Ala,0.6316,0,0.047963187029568956,115.49535436720204,0.0,0.05264480080801909,126.76868034570997,0.0,ambiguous
2350,HNEAP_RS02720,,,576038,578936,2898.0,+,23S ribosomal RNA,0.5336,121,1.0722261630848924e-51,2.581920600708421e-48,0.0,4.586251454060717e-48,1.1043693501378207e-44,1.0,essential
2351,HNEAP_RS02725,,,579028,579143,115.0,+,5S ribosomal RNA,0.5776,2,0.00949275598843634,22.858556420154706,0.0,0.010949940174792352,26.367455940899983,0.0,ambiguous
2352,GFF559,,,591909,592172,263.0,+,hypothetical protein,0.5947,5,0.5273074136983825,1269.756252185705,10.0,0.5672046374193886,1365.828766905888,10.0,nonessential
2353,HNEAP_RS02840,,,596032,596107,75.0,+,tRNA-Ala,0.6316,1,0.047963187029568956,115.49535436720204,0.0,0.05264480080801909,126.76868034570997,0.0,ambiguous
2354,HNEAP_RS02845,,,596413,596502,89.0,-,tRNA-Ser,0.5778,1,0.027206804295101042,65.51398474260331,0.0,0.03038611503541589,73.16976500528146,0.0,ambiguous
2355,HNEAP_RS03120,,,664507,664583,76.0,-,tRNA-Arg,0.6104,3,0.9999911659884946,2407.978727700295,12.0,0.9993328849088045,2406.3935868604012,9.0,nonessential
2356,GFF718,,,775348,777476,2128.0,+,flagellar biosynthesis protein FlhA,0.5636,37,0.9999231673013173,2407.814986861572,120.0,0.9998327840524964,2407.5973439984114,115.0,nonessential
2357,GFF782,,,840246,841510,1264.0,-,hypothetical protein,0.5296,32,0.8542697987880707,2057.081675481674,57.0,0.8415913586396848,2026.551991604361,55.0,nonessential
2358,HNEAP_RS03970,,,847106,847180,74.0,+,tRNA-Val,0.5733,1,0.04994544949616701,120.26864238677017,0.0,0.2169679701038937,522.458872010176,1.0,nonessential
2359,HNEAP_RS04050,,,867431,867517,86.0,-,tRNA-Leu,0.5632,3,0.33170783200708764,798.752459473067,2.0,0.5766661007451466,1388.6119705943129,3.0,nonessential
2360,HNEAP_RS04070,,,871728,871801,73.0,-,tRNA-Gly,0.5405,2,0.05200963655389077,125.23920482176898,0.0,0.05694461667234833,137.1226369470148,0.0,ambiguous
2361,HNEAP_RS04140,,,887901,887977,76.0,+,tRNA-Pro,0.6104,2,0.04605959768587042,110.91151122757596,0.0,0.050618222825274,121.8886805632598,0.0,ambiguous
2362,GFF824,,,888262,888492,230.0,+,hypothetical protein,0.5628,4,0.9778131492942943,2354.5740635006605,15.0,0.9660370762806884,2326.2172796838977,14.0,nonessential
2363,GFF879,,,945249,945765,516.0,-,hypothetical protein,0.4681,19,0.5157408767451969,1241.904031202434,20.0,0.48089713468310236,1158.0003003169104,19.0,nonessential
2364,GFF880,,,945727,946883,1156.0,+,IS3 family transposase,0.5385,27,0.9562384946147154,2302.622295032235,57.0,0.9498878567294075,2287.329959004413,55.0,nonessential
2365,GFF881,,,946889,947352,463.0,+,GNAT family N-acetyltransferase,0.5517,11,0.9883848094457859,2380.030621145452,28.0,0.9920934830313828,2388.96110713957,28.0,nonessential
2366,HNEAP_RS04700,,,998522,998608,86.0,+,tRNA-Leu,0.5517,2,0.03072141473817346,73.9771666895217,0.0,0.034183848746062166,82.3147077805177,0.0,ambiguous
2367,GFF949,,,1018025,1019295,1270.0,+,IS110 family transposase,0.5799,22,6.586807631675501e-20,1.5861032777074605e-16,2.0,2.9958907419744764e-19,7.214104906674539e-16,2.0,essential
2368,GFF951,,,1023010,1024134,1124.0,+,IS3 family transposase,0.552,25,0.3239133794457457,779.9834177053557,41.0,0.34106159204769604,821.2763136508521,40.0,nonessential
2369,HNEAP_RS04890,,,1051100,1051176,76.0,-,tRNA-Arg,0.6234,3,0.19073238780696025,459.2835898391603,1.0,0.20463814951390177,492.7686640294755,1.0,nonessential
2370,HNEAP_RS04985,,,1069553,1069629,76.0,+,tRNA-Pro,0.5714,3,0.04605959768587042,110.91151122757596,0.0,0.050618222825274,121.8886805632598,0.0,ambiguous
2371,HNEAP_RS04990,,,1069645,1069721,76.0,+,tRNA-Arg,0.6623,3,0.04605959768587042,110.91151122757596,0.0,0.050618222825274,121.8886805632598,0.0,ambiguous
2372,HNEAP_RS04995,,,1069743,1069818,75.0,+,tRNA-His,0.5921,1,0.047963187029568956,115.49535436720204,0.0,0.05264480080801909,126.76868034570997,0.0,ambiguous
2373,HNEAP_RS05000,,,1070020,1070096,76.0,+,tRNA-Met,0.5195,4,0.04605959768587042,110.91151122757596,0.0,0.050618222825274,121.8886805632598,0.0,ambiguous
2374,HNEAP_RS05485,,,1179338,1179414,76.0,+,tRNA-Met,0.5974,4,0.04605959768587042,110.91151122757596,0.0,0.050618222825274,121.8886805632598,0.0,ambiguous
2375,HNEAP_RS05735,,,1242178,1242253,75.0,-,tRNA-Glu,0.6447,3,0.19663287202442295,473.4919558348105,1.0,0.21072343573728922,507.4220332553924,1.0,nonessential
2376,HNEAP_RS05740,,,1242307,1242382,75.0,-,tRNA-Glu,0.6447,3,0.047963187029568956,115.49535436720204,0.0,0.05264480080801909,126.76868034570997,0.0,ambiguous
2377,HNEAP_RS05745,,,1242384,1242460,76.0,-,tRNA-Arg,0.5974,4,0.04605959768587042,110.91151122757596,0.0,0.050618222825274,121.8886805632598,0.0,ambiguous
2378,HNEAP_RS05750,,,1242462,1242537,75.0,-,tRNA-Asn,0.5132,3,0.047963187029568956,115.49535436720204,0.0,0.05264480080801909,126.76868034570997,0.0,ambiguous
2379,HNEAP_RS05880,,,1272623,1272699,76.0,+,tRNA-Gln,0.5714,1,0.19073238780696025,459.2835898391603,1.0,0.050618222825274,121.8886805632598,0.0,nonessential
2380,GFF1190,,,1295437,1297511,2074.0,-,hypothetical protein,0.5557,54,0.9999999999987944,2407.999999997097,151.0,0.9999999999990564,2407.999999997728,148.0,nonessential
2381,GFF1209,,,1313373,1313610,237.0,-,hypothetical protein,0.6975,0,0.985608583180198,2373.345468297917,16.0,0.9890408512634087,2381.610369842288,16.0,nonessential
2382,HNEAP_RS06125,,,1319195,1319279,84.0,+,tRNA-Leu,0.5176,5,0.03331324947128111,80.2183047268449,0.0,0.03697584820063623,89.03784246713204,0.0,ambiguous
2383,GFF1270,,,1373793,1374916,1123.0,-,rod shape-determining protein RodA,0.5383,18,1.7733574456926496e-20,4.2702447292279e-17,0.0,7.152032656837231e-20,1.7222094637664052e-16,0.0,essential
2384,HNEAP_RS06530,,,1410342,1410417,75.0,+,tRNA-Gly,0.5921,1,0.047963187029568956,115.49535436720204,0.0,0.05264480080801909,126.76868034570997,0.0,ambiguous
2385,HNEAP_RS06535,,,1410422,1410495,73.0,+,tRNA-Cys,0.5676,2,0.05200963655389077,125.23920482176898,0.0,0.05694461667234833,137.1226369470148,0.0,ambiguous
2386,GFF1357,,,1467103,1468206,1103.0,-,hypothetical protein,0.6123,14,0.9996868420990743,2407.245915774571,67.0,0.9976065525634571,2402.236578572805,61.0,nonessential
2387,HNEAP_RS07055,,,1518125,1518200,75.0,+,tRNA-Thr,0.5526,4,0.999992400936287,2407.9817014545793,12.0,0.9999711903811674,2407.930626437851,11.0,nonessential
2388,GFF1439,,,1552270,1555381,3111.0,+,multidrug efflux protein,0.5437,67,0.0001802696383467093,0.434089289138876,86.0,0.0005954362876631755,1.4338105806929264,86.0,nonessential
2389,HNEAP_RS07420,,,1601354,1601444,90.0,+,tRNA-Ser,0.5934,4,0.9991124573687274,2405.8627973438956,10.0,0.9993077132888484,2406.3329735995467,10.0,nonessential
2390,GFF1496,,,1618549,1618814,265.0,+,hypothetical protein,0.3947,12,0.09614294688083465,231.51221608904984,6.0,0.056420046047938904,135.85947088343687,5.0,nonessential
2391,GFF1606,,,1748266,1748562,296.0,+,hypothetical protein,0.5623,7,0.7105092673405626,1710.9063157560747,13.0,0.6462082307679912,1556.0694196893228,12.0,nonessential
2392,GFF1629,,,1769915,1770478,563.0,-,hypothetical protein,0.5124,21,0.6104089158327854,1469.8646693253474,23.0,0.6658251083058062,1603.3068608003814,23.0,nonessential
2393,GFF1646,,,1782979,1783134,155.0,-,integrase,0.4615,4,0.5814714339371054,1400.18321292055,6.0,0.6117661326154158,1473.1328473379212,6.0,nonessential
2394,GFF1704,,,1837853,1838244,391.0,-,hypothetical protein,0.5102,10,0.9999964641542383,2407.9914856834057,35.0,0.9999720705613722,2407.932745911784,32.0,nonessential
2395,GFF1835,,,1981905,1983290,1385.0,+,cytochrome C,0.5368,38,0.2736423682168222,658.9308226661078,50.0,0.210355094650076,506.53506791738306,47.0,nonessential
2396,HNEAP_RS09775,,,2100594,2100678,84.0,-,tRNA-Leu,0.6,3,0.03331324947128111,80.2183047268449,0.0,0.03697584820063623,89.03784246713204,0.0,ambiguous
2397,GFF2046,,,2198879,2199427,548.0,-,hypothetical protein,0.5902,6,0.17712199074346133,426.50975371025487,17.0,0.1529809564941684,368.3781432379575,16.0,nonessential
2398,HNEAP_RS10635,,,2291179,2291294,115.0,-,5S ribosomal RNA,0.5776,3,0.00949275598843634,22.858556420154706,0.0,0.010949940174792352,26.367455940899983,0.0,ambiguous
2399,HNEAP_RS10640,,,2291387,2294285,2898.0,-,23S ribosomal RNA,0.5333,121,1.0722261630848924e-51,2.581920600708421e-48,0.0,3.91900673145319e-50,9.436968209339282e-47,0.0,essential
2400,HNEAP_RS10645,,,2294499,2294574,75.0,-,tRNA-Ala,0.6316,1,0.047963187029568956,115.49535436720204,0.0,0.05264480080801909,126.76868034570997,0.0,ambiguous
2401,HNEAP_RS10650,,,2294856,2294932,76.0,-,tRNA-Ile,0.5974,3,0.04605959768587042,110.91151122757596,0.0,0.050618222825274,121.8886805632598,0.0,ambiguous
2402,HNEAP_RS10655,,,2295002,2296539,1537.0,-,16S ribosomal RNA,0.5364,62,9.277022834983125e-28,2.2339070986639366e-24,0.0,6.2562165944950656e-27,1.5064969559544117e-23,0.0,essential
2403,GFF2212,,,2387560,2387873,313.0,+,hypothetical protein,0.5414,11,0.9998394414823267,2407.613375089443,26.0,0.9999016320100093,2407.7631298801025,26.0,nonessential
2404,GFF2252,,,2428426,2430055,1629.0,+,IS66 family transposase,0.5804,31,0.9999999953788076,2407.9999888721686,114.0,0.9999999991257071,2407.9999978947026,114.0,nonessential
2405,GFF2279,,,2459115,2459623,508.0,+,IS3 family transposase,0.558,8,0.6314308208432893,1520.4854165906406,21.0,0.5992939855229658,1443.0999171393016,20.0,nonessential
2406,GFF2280,,,2459735,2460131,396.0,+,IS3 family transposase,0.5491,8,0.493621379725925,1188.6402823800274,15.0,0.5426151865880045,1306.6173693039148,15.0,nonessential
2407,GFF2288,,,2466469,2467128,659.0,-,pilus assembly protein TadE,0.5621,16,6.796988975788948e-08,0.00016367149453699786,4.0,1.36377607984464e-07,0.0003283972800265893,4.0,essential