Category Term Count % PValue Genes List Total Pop Hits Pop Total Fold Enrichment Bonferroni Benjamini FDR GOTERM_BP_DIRECT GO:0010628~positive regulation of gene expression 32 9.142857142857142 6.220053941247654E-10 RET, EDA, SLC24A3, CSF1, CITED2, ROCK2, SERPINE1, PIK3CB, DLL1, FGF5, CNN2, TRIM6, CYP26B1, CDH3, CCL2, EPHB2, LDLR, FGF21, JAG1, OSR1, NTRK3, NOG, NRG1, SOX11, INHBA, KLF4, BMP6, BMP4, ADM2, FGF18, ATF4, RBMS3 290 590 19984 3.737510227936879 1.4548696830596342E-6 1.0346724110975623E-6 1.0174204983002965E-6 GOTERM_BP_DIRECT GO:0007275~multicellular organism development 45 12.857142857142856 8.847134767828664E-10 RET, ADCYAP1R1, WNT2B, DDX4, PKDCC, EDA, CITED2, SEMA3D, SEMA3E, DACH2, DLL1, EFNB2, CDH6, SMPD3, JPH2, CHL1, INSC, HOXA1, EPHB2, PAK3, PRKCI, JAG1, TNFRSF12A, GADD45B, SIAH2, NTRK3, FST, NOG, SHROOM2, SHROOM3, EBF3, SOX11, GDF6, BMP6, BICC1, GADD45G, APLN, BMP4, MN1, BMP3, SFRP2, PI15, ROR1, TLL1, EPHA1 290 1102 19984 2.813943300582014 2.0693427940088327E-6 1.0346724110975623E-6 1.0174204983002965E-6 GOTERM_BP_DIRECT GO:0006695~cholesterol biosynthetic process 10 2.857142857142857 7.171516781642954E-9 IDI1, HMGCS1, INSIG1, DHCR24, MSMO1, DHCR7, HMGCR, LSS, CFTR, CYP51 290 42 19984 16.407224958949097 1.6774037227662575E-5 5.591392584087623E-6 5.498162865926265E-6 GOTERM_BP_DIRECT GO:0030335~positive regulation of cell migration 19 5.428571428571429 8.265432247213314E-8 RET, EDN1, CEMIP, HSPA5, CSF1, ROCK2, SEMA3D, NTRK3, RRAS2, NEDD9, SEMA3E, THBS1, CLDN1, BMP4, SH3RF2, CASS4, F2RL1, EPHA1, EPHB2 290 269 19984 4.867273426483785 1.933097815671747E-4 4.833211506557986E-5 4.7526235421476556E-5 GOTERM_BP_DIRECT GO:0016126~sterol biosynthetic process 8 2.2857142857142856 1.883528147452569E-7 SQLE, HMGCS1, INSIG1, DHCR24, MSMO1, DHCR7, HMGCR, CYP51 290 30 19984 18.37609195402299 4.404602441759886E-4 8.811144673783117E-5 8.664229478281817E-5 GOTERM_BP_DIRECT GO:0006629~lipid metabolic process 30 8.571428571428571 8.791666602386006E-7 ACSS2, HPGD, INSIG1, MSMO1, PIK3CB, HMGCR, PLCXD2, FADS3, SMPD3, LACTB, UGCG, CYP26B1, LDLR, HMGCS1, MID1IP1, APOBR, DHCR24, ELOVL6, ACSL3, LSS, CYP51, SQLE, SOAT2, FASN, CTH, PNPLA3, DHCR7, BCAT1, MGLL, DGKI 290 728 19984 2.8397120121258053 0.0020542588384819815 3.427284697163478E-4 3.3701388642479684E-4 GOTERM_BP_DIRECT GO:0008203~cholesterol metabolic process 11 3.1428571428571432 9.099132453357824E-6 SQLE, HMGCS1, SOAT2, INSIG1, APOBR, DHCR24, MSMO1, DHCR7, HMGCR, LDLR, CYP51 290 119 19984 6.369863807592002 0.021058083507289882 0.003040410115486279 0.0029897149489604277 GOTERM_BP_DIRECT GO:0030336~negative regulation of cell migration 12 3.428571428571429 1.5425842275510848E-5 CNN2, JAG1, SFRP2, LIMCH1, CITED2, SERPINE1, TPM1, NOG, NEDD9, STC1, KLF4, EPHA1 290 154 19984 5.369637259292432 0.03543815113205517 0.004086357271837018 0.004018222199754228 GOTERM_BP_DIRECT GO:0030154~cell differentiation 34 9.714285714285714 1.5723478172951327E-5 TDRKH, ADCYAP1R1, DDX4, PKDCC, EDA, CITED2, SEMA3D, SEMA3E, DLL1, EFNB2, FGF5, UGCG, CHL1, INSC, FGF21, TNFRSF12A, GADD45B, OSR1, NTRK3, FST, NOG, NRG1, SOX11, KLF4, SMAD6, BMP6, GADD45G, BMP4, BMP3, SFRP2, FGF18, TLL1, DHCR7, ZFPM2 290 1028 19984 2.279135918422112 0.036109427271947325 0.004086357271837018 0.004018222199754228 GOTERM_BP_DIRECT GO:0007155~cell adhesion 24 6.857142857142858 2.2957325600073403E-5 RET, FARP2, CXADR, TNFRSF12A, PCDH10, NEDD9, PIK3CB, THBS1, CLDN1, SIGLECG, EFNB2, CDH6, BCAN, NUAK1, CDH3, CLDN15, CHL1, CASS4, CNTN2, CDH26, FAT4, EPHA1, AJUBA, VCL 290 600 19984 2.756413793103448 0.05228153715895467 0.005369718457857169 0.0052801848880168825 GOTERM_BP_DIRECT GO:0007169~transmembrane receptor protein tyrosine kinase signaling pathway 10 2.857142857142857 5.514741435737849E-5 RET, CSF1, BDNF, NTRK3, CASS4, NEDD9, ROR1, NRG1, EPHB2, EPHA1 290 118 19984 5.839859731151373 0.12102019720390889 0.011726345652900753 0.011530823001997322 GOTERM_BP_DIRECT GO:0008284~positive regulation of cell proliferation 24 6.857142857142858 6.660323364258117E-5 IL11, EDN1, TSLP, CSF1, NTRK3, NOG, IL31RA, ADM, NRG1, SOX11, HMGCR, THBS1, DLL1, AGTR1A, APLN, FGF5, EFNB2, BMP4, SFRP2, THPO, FGF18, IL6ST, EPHA1, FGF21 290 643 19984 2.572081299941009 0.14426125307251247 0.01218084038286872 0.011977739581273216 GOTERM_BP_DIRECT GO:0071300~cellular response to retinoic acid 8 2.2857142857142856 6.770026719850078E-5 RET, CYP26B1, NTRK3, OSR1, CCL2, HOXA1, KLF4, TEAD1 290 70 19984 7.875467980295566 0.14645437807188366 0.01218084038286872 0.011977739581273216 GOTERM_BP_DIRECT GO:0007399~nervous system development 19 5.428571428571429 7.74246331926604E-5 RET, PRDM8, BDNF, SEMA3D, NTRK3, CRMP1, NRG1, SOX11, SEMA3E, LRP2, DLL1, EFNB2, CHL1, INSC, FGF18, IGF2BP1, HOXA1, CHAC1, EPHB2 290 439 19984 2.9824522818317494 0.16565077399652073 0.01293544407411662 0.012719761167365637 GOTERM_BP_DIRECT GO:0001525~angiogenesis 15 4.285714285714286 8.665385092925333E-5 TNFRSF12A, SERPINE1, NPR3, SEMA3E, AMOT, APLN, EFNB2, BMP4, ADM2, FGF18, CCL2, RSPO3, AMOTL2, EPHA1, EPHB2 290 289 19984 3.5766614962414987 0.18347042004183844 0.013512223821568236 0.013286923809152178 GOTERM_BP_DIRECT GO:0035329~hippo signaling 5 1.4285714285714286 1.7288216075038833E-4 AMOTL2, FAT4, TEAD1, AMOT, TEAD3 290 20 19984 17.227586206896554 0.3326271090091203 0.02429845177167657 0.02389330443559474 GOTERM_BP_DIRECT GO:0008202~steroid metabolic process 10 2.857142857142857 1.8393191091963917E-4 HMGCS1, SOAT2, INSIG1, APOBR, DHCR24, MSMO1, DHCR7, HMGCR, LDLR, CYP51 290 138 19984 4.993503248375812 0.34965761575828813 0.02429845177167657 0.02389330443559474 GOTERM_BP_DIRECT GO:0003151~outflow tract morphogenesis 7 2.0 1.8699107819161102E-4 BMP4, SFRP2, CITED2, NOG, SOX11, ZFPM2, THBS1 290 58 19984 8.316765755053508 0.3542953186465253 0.02429845177167657 0.02389330443559474 GOTERM_BP_DIRECT GO:0033574~response to testosterone 6 1.7142857142857144 2.656100500682656E-4 EDN1, TBXA2R, CACNA1B, THBS1, PSPH, FOXP2 290 40 19984 10.336551724137932 0.46277830425239264 0.03269799511103544 0.032152795534579524 GOTERM_BP_DIRECT GO:0010976~positive regulation of neuron projection development 11 3.1428571428571432 3.1541508948434733E-4 RET, BMP4, PRKCI, HSPA5, ADAMTS1, BDNF, DYNLT1C, NTRK3, ANKRD1, ROR1, NRG1 290 181 19984 4.18792150885883 0.5218698333746374 0.03688779471519442 0.036272735290699944 GOTERM_BP_DIRECT GO:0001501~skeletal system development 9 2.571428571428571 3.810099579059211E-4 SMPD3, BMP4, BCAN, EDN1, PKDCC, FST, NPR3, NOG, SOX11 290 121 19984 5.125562838415503 0.589899123516 0.04155727893825344 0.04086436150405426 GOTERM_BP_DIRECT GO:0008360~regulation of cell shape 10 2.857142857142857 3.9627873307284816E-4 SPTA1, PALMD, TPM1, CDC42EP3, SHROOM3, CCL2, CDC42EP1, SEMA3E, RND3, RND1 290 153 19984 4.503944106378183 0.6042923744620898 0.04155727893825344 0.04086436150405426 GOTERM_BP_DIRECT GO:0007411~axon guidance 11 3.1428571428571432 4.2469529451860595E-4 EFNB2, BDNF, CHL1, SEMA3D, TUBB3, NOG, CRMP1, CNTN2, SEMA3E, EPHB2, EPHA1 290 188 19984 4.0319882611885545 0.6297486915092929 0.04155727893825344 0.04086436150405426 GOTERM_BP_DIRECT GO:0008652~cellular amino acid biosynthetic process 5 1.4285714285714286 4.264107287379575E-4 PSAT1, CTH, ASNS, BCAT1, PSPH 290 25 19984 13.782068965517242 0.6312319416100124 0.04155727893825344 0.04086436150405426 GOTERM_BP_DIRECT GO:0016125~sterol metabolic process 4 1.1428571428571428 4.5317428452113526E-4 CYP26B1, DHCR24, LSS, CYP51 290 11 19984 25.058307210031348 0.6536186352694227 0.04239898605979742 0.04169203417594444 GOTERM_BP_DIRECT GO:0006694~steroid biosynthetic process 7 2.0 4.850440350524815E-4 HMGCS1, DHCR24, MSMO1, DHCR7, HMGCR, LSS, CYP51 290 69 19984 6.990904547726137 0.6785114121733573 0.043635307614913625 0.04290774156233491 GOTERM_BP_DIRECT GO:0045766~positive regulation of angiogenesis 10 2.857142857142857 5.489155077461538E-4 SFRP2, DDAH1, TBXA2R, ADM2, SERPINE1, FGF18, ADM, EPHA1, THBS1, AGTR1A 290 160 19984 4.306896551724138 0.7231462475191777 0.04598122286335809 0.04521454150736366 GOTERM_BP_DIRECT GO:0048839~inner ear development 7 2.0 5.65706887640776E-4 JAG1, CEBPD, BDNF, HOXA1, ROR1, LGR5, DLL1 290 71 19984 6.793977659057795 0.7338147595236635 0.04598122286335809 0.04521454150736366 GOTERM_BP_DIRECT GO:0010460~positive regulation of heart rate 5 1.4285714285714286 5.782870725370674E-4 RGS4, EDN1, ADM2, ADM, APLN 290 27 19984 12.761174968071519 0.7415375128436781 0.04598122286335809 0.04521454150736366 GOTERM_BP_DIRECT GO:0045471~response to ethanol 9 2.571428571428571 6.152524705728625E-4 RGS4, ADCYAP1R1, HPGD, TBXA2R, NTRK3, CCL2, HTR1B, HMGCR, CLDN1 290 130 19984 4.770716180371353 0.7629581112588057 0.04598122286335809 0.04521454150736366 GOTERM_BP_DIRECT GO:0016525~negative regulation of angiogenesis 8 2.2857142857142856 6.25802848250552E-4 ADAMTS1, ROCK2, HHIP, CCL2, SEMA3E, KLF4, THBS1, AMOT 290 100 19984 5.512827586206897 0.7687396307478583 0.04598122286335809 0.04521454150736366 GOTERM_BP_DIRECT GO:0001657~ureteric bud development 6 1.7142857142857144 6.290718818415813E-4 RET, BMP4, BDNF, OSR1, NOG, SMAD6 290 48 19984 8.613793103448277 0.7705022684220617 0.04598122286335809 0.04521454150736366 GOTERM_BP_DIRECT GO:0010629~negative regulation of gene expression 16 4.571428571428571 6.768058159091374E-4 EDN1, SLC24A3, ROCK2, CITED2, SERPINE1, NOG, SOX11, KLF4, APLN, BMP4, SLC7A5, TRIM6, SFRP2, STC2, LDLR, RBMS3 290 395 19984 2.7913051069402006 0.7947619499057853 0.04797117586095371 0.047171314442152 GOTERM_BP_DIRECT GO:0001843~neural tube closure 8 2.2857142857142856 7.045186337849373E-4 BMP4, SFRP2, CITED2, ROCK2, NOG, SHROOM3, ADM, LRP2 290 102 19984 5.40473292765382 0.8076521513571944 0.04846673777714613 0.047658613461922225 GOTERM_BP_DIRECT GO:0045669~positive regulation of osteoblast differentiation 7 2.0 9.326780141547928E-4 BMP4, JAG1, SFRP2, CEBPD, SOX11, IL6ST, BMP6 290 78 19984 6.184261715296198 0.8872465657919912 0.06232953928880172 0.061290269501600665 GOTERM_BP_DIRECT GO:0001822~kidney development 10 2.857142857142857 0.0010828439144374017 BMP4, CYP26B1, HPGD, ADAMTS1, SOX11, LRP2, FAT4, BMP6, AGTR1A, BICC1 290 176 19984 3.915360501567398 0.9206704199138384 0.06962482408310207 0.06846391423306317 GOTERM_BP_DIRECT GO:0035690~cellular response to drug 7 2.0 0.001136784823452221 EDN1, HSPA5, SERPINE1, ANKRD1, CCL2, HTR1B, FGF21 290 81 19984 5.955214985100043 0.9300833995614323 0.06962482408310207 0.06846391423306317 GOTERM_BP_DIRECT GO:0002244~hematopoietic progenitor cell differentiation 8 2.2857142857142856 0.0011609098500388972 SMPD3, BMP4, CEBPD, PTPRQ, CITED2, FST, INHBA, SIGLECG 290 111 19984 4.966511338925132 0.9339237241102516 0.06962482408310207 0.06846391423306317 GOTERM_BP_DIRECT GO:0030509~BMP signaling pathway 8 2.2857142857142856 0.0011609098500388972 SMPD3, BMP4, SFRP2, FST, NOG, SMAD6, GDF6, BMP6 290 111 19984 4.966511338925132 0.9339237241102516 0.06962482408310207 0.06846391423306317 GOTERM_BP_DIRECT GO:0032270~positive regulation of cellular protein metabolic process 4 1.1428571428571428 0.0014577908763774552 CSF1, INHBA, KLF4, AGTR1A 290 16 19984 17.227586206896554 0.9670334097098607 0.08330202062230589 0.08191306003903528 GOTERM_BP_DIRECT GO:0008217~regulation of blood pressure 7 2.0 0.0014601893311306292 EDN1, LVRN, NPR3, CACNA1B, ADRA1D, DLL1, AGTR1A 290 85 19984 5.674969574036512 0.967218102726507 0.08330202062230589 0.08191306003903528 GOTERM_BP_DIRECT GO:0007507~heart development 13 3.7142857142857144 0.0015211015367123254 EDN1, CXADR, CITED2, NTRK3, OSR1, ADM, NRG1, LRP2, AGTR1A, BICC1, BMP4, ZFPM2, TEAD1 290 301 19984 2.9761942948791384 0.9715772435719188 0.08376051311994256 0.08236390772803245 GOTERM_BP_DIRECT GO:0007015~actin filament organization 9 2.571428571428571 0.0015555836023846538 PRKCI, TPM1, FSCN1, LMOD1, FAT1, SHROOM2, SHROOM3, RND3, RND1 290 150 19984 4.134620689655172 0.9737828889416895 0.08376051311994256 0.08236390772803245 GOTERM_BP_DIRECT GO:0001503~ossification 8 2.2857142857142856 0.0015756573652319253 SMPD3, BMP4, BMP3, PKDCC, CSF1, FGF18, STC1, BMP6 290 117 19984 4.711818449749485 0.9749872389907566 0.08376051311994256 0.08236390772803245 GOTERM_BP_DIRECT GO:0016477~cell migration 13 3.7142857142857144 0.0021146135927713906 PRKCI, SHROOM2, RRAS2, NEDD9, NRG1, PIK3CB, THBS1, RND3, RND1, SYDE2, FSCN1, FAT1, CASS4 290 313 19984 2.8620909992288204 0.9929259215810943 0.10968008092107999 0.1078512980412501 GOTERM_BP_DIRECT GO:0009887~animal organ morphogenesis 9 2.571428571428571 0.002157025960825002 FGF5, EFNB2, JAG1, WNT2B, HHIP, FGF18, EPHB2, DLL1, FGF21 290 158 19984 3.9252728066346574 0.9935953626423352 0.10968008092107999 0.1078512980412501 GOTERM_BP_DIRECT GO:0043410~positive regulation of MAPK cascade 10 2.857142857142857 0.002272478099310589 RET, BMP4, IL11, GADD45B, THPO, ROCK2, NTRK3, ROR1, ADRA1D, GADD45G 290 196 19984 3.5158339197748063 0.9951139688016386 0.11309204838909506 0.11120637507264584 GOTERM_BP_DIRECT GO:0051216~cartilage development 7 2.0 0.0025743481800919697 SMPD3, BMP4, BMP3, EDN1, SFRP2, NOG, BMP6 290 95 19984 5.077604355716878 0.9975924949371742 0.1254458415257316 0.12335418362940688 GOTERM_BP_DIRECT GO:0009612~response to mechanical stimulus 6 1.7142857142857144 0.0028400434074057753 CITED2, PIEZO2, CCL2, ASNS, THBS1, PSPH 290 67 19984 6.17107565620175 0.9987089667803112 0.1355686026514716 0.13330815993945477 GOTERM_BP_DIRECT GO:0061156~pulmonary artery morphogenesis 3 0.8571428571428572 0.0030085269284972904 JAG1, CITED2, LRP2 290 6 19984 34.45517241379311 0.9991304643142115 0.14033751552823154 0.1379975569537976 GOTERM_BP_DIRECT GO:1904707~positive regulation of vascular smooth muscle cell proliferation 5 1.4285714285714286 0.003112300260003053 EDN1, HPGD, ADAMTS1, HTR1B, AGTR1A 290 42 19984 8.203612479474549 0.9993183690173227 0.14033751552823154 0.1379975569537976 GOTERM_BP_DIRECT GO:0051897~positive regulation of protein kinase B signaling 8 2.2857142857142856 0.0031199447659119453 RET, THPO, CASS4, TNFAIP8L3, NRG1, PIK3CB, LRP2, THBS1 290 132 19984 4.176384535005225 0.9993304860248163 0.14033751552823154 0.1379975569537976 GOTERM_BP_DIRECT GO:0033674~positive regulation of kinase activity 6 1.7142857142857144 0.0032286843751813854 RET, NTRK3, ROR1, EPHB2, EPHA1, AJUBA 290 69 19984 5.992203898050975 0.9994812613663263 0.14248854251979737 0.1401127181682488 GOTERM_BP_DIRECT GO:0030182~neuron differentiation 11 3.1428571428571432 0.0034002334930733655 RET, JAG1, WNT2B, HSPA5, TUBB3, CNTN2, SOX11, ACSL3, DLL1, BMP6, ATF4 290 248 19984 3.0565072302558396 0.9996531777461326 0.1461544963489669 0.1437175466449867 GOTERM_BP_DIRECT GO:0009790~embryo development 6 1.7142857142857144 0.0034367239415105514 DLG2, OSR1, TPM1, HMGCR, FOXP2, AMOT 290 70 19984 5.906600985221675 0.9996816445642249 0.1461544963489669 0.1437175466449867 GOTERM_BP_DIRECT GO:0032332~positive regulation of chondrocyte differentiation 4 1.1428571428571428 0.0037601822130025613 PKDCC, FGF18, GDF6, BMP6 290 22 19984 12.529153605015674 0.9998510117762325 0.1542994069511051 0.15172665070010335 GOTERM_BP_DIRECT GO:0042310~vasoconstriction 4 1.1428571428571428 0.0037601822130025613 EDN1, HTR1B, SMAD6, AGTR1A 290 22 19984 12.529153605015674 0.9998510117762325 0.1542994069511051 0.15172665070010335 GOTERM_BP_DIRECT GO:0090190~positive regulation of branching involved in ureteric bud morphogenesis 4 1.1428571428571428 0.0042784061161275965 BMP4, WNT2B, NOG, AGTR1A 290 23 19984 11.984407796101948 0.9999558827889099 0.16678653176037414 0.1640055677848912 GOTERM_BP_DIRECT GO:0042491~auditory receptor cell differentiation 4 1.1428571428571428 0.0042784061161275965 BMP4, MCOLN3, JAG1, DLL1 290 23 19984 11.984407796101948 0.9999558827889099 0.16678653176037414 0.1640055677848912 GOTERM_BP_DIRECT GO:2000353~positive regulation of endothelial cell apoptotic process 4 1.1428571428571428 0.0042784061161275965 BMP4, PRKCI, CCL2, THBS1 290 23 19984 11.984407796101948 0.9999558827889099 0.16678653176037414 0.1640055677848912 GOTERM_BP_DIRECT GO:0060070~canonical Wnt signaling pathway 7 2.0 0.004853737803468437 EDN1, EDA, WNT2B, SFRP2, SIAH2, RSPO3, KLF4 290 108 19984 4.466411238825032 0.9999885844509919 0.18611299544774876 0.1830097860324165 GOTERM_BP_DIRECT GO:0048593~camera-type eye morphogenesis 4 1.1428571428571428 0.005439412679502473 BMP4, FAT1, SHROOM2, EPHB2 290 25 19984 11.025655172413794 0.9999971194073138 0.20520622995735943 0.2017846639170272 GOTERM_BP_DIRECT GO:0007265~Ras protein signal transduction 6 1.7142857142857144 0.005763039919857852 CSF1, RRAS2, DHCR24, DGKI, RALGPS1, RASGRP3 290 79 19984 5.233697075512876 0.9999986544967119 0.21239212533535892 0.20885074316858723 GOTERM_BP_DIRECT GO:0010862~positive regulation of pathway-restricted SMAD protein phosphorylation 5 1.4285714285714286 0.005852335836397282 BMP4, BMP3, INHBA, GDF6, BMP6 290 50 19984 6.891034482758621 0.9999989094470206 0.21239212533535892 0.20885074316858723 GOTERM_BP_DIRECT GO:0060548~negative regulation of cell death 7 2.0 0.006038461963372572 BMP4, ADCYAP1R1, BDNF, DYNLT1C, NTRK3, SOX11, ZFPM2 290 113 19984 4.268782422947818 0.9999992962048381 0.21239212533535892 0.20885074316858723 GOTERM_BP_DIRECT GO:0050770~regulation of axonogenesis 4 1.1428571428571428 0.006083912953171889 RET, SIPA1L1, PAK3, EPHB2 290 26 19984 10.60159151193634 0.9999993675955183 0.21239212533535892 0.20885074316858723 GOTERM_BP_DIRECT GO:0042474~middle ear morphogenesis 4 1.1428571428571428 0.006083912953171889 EDN1, INSIG1, OSR1, NOG 290 26 19984 10.60159151193634 0.9999993675955183 0.21239212533535892 0.20885074316858723 GOTERM_BP_DIRECT GO:0060395~SMAD protein signal transduction 6 1.7142857142857144 0.006401186563344723 BMP4, BMP3, INHBA, SMAD6, GDF6, BMP6 290 81 19984 5.104469987228608 0.9999997003052383 0.21699094741541025 0.2133728854448241 GOTERM_BP_DIRECT GO:0032956~regulation of actin cytoskeleton organization 6 1.7142857142857144 0.006401186563344723 ROCK2, FSCN1, NEDD9, PAK3, RND3, RND1 290 81 19984 5.104469987228608 0.9999997003052383 0.21699094741541025 0.2133728854448241 GOTERM_BP_DIRECT GO:0043406~positive regulation of MAP kinase activity 6 1.7142857142857144 0.006738152985975154 GPR39, EDN1, NTRK3, FGF18, THBS1, AJUBA 290 82 19984 5.042220353238014 0.9999998644435982 0.21999971894360776 0.21633148934172627 GOTERM_BP_DIRECT GO:0051247~positive regulation of protein metabolic process 4 1.1428571428571428 0.006772116188088823 CSF1, INHBA, KLF4, AGTR1A 290 27 19984 10.208939974457214 0.9999998748631929 0.21999971894360776 0.21633148934172627 GOTERM_BP_DIRECT GO:0003148~outflow tract septum morphogenesis 4 1.1428571428571428 0.006772116188088823 BMP4, LRP2, ZFPM2, SMAD6 290 27 19984 10.208939974457214 0.9999998748631929 0.21999971894360776 0.21633148934172627 GOTERM_BP_DIRECT GO:0034351~negative regulation of glial cell apoptotic process 3 0.8571428571428572 0.007016227078349045 PRKCI, CCL2, DLL1 290 9 19984 22.970114942528735 0.9999999295806212 0.22438360840257682 0.2206422827387459 GOTERM_BP_DIRECT GO:1902895~positive regulation of pri-miRNA transcription from RNA polymerase II promoter 5 1.4285714285714286 0.0071948570458286705 BMP4, KLF4, SMAD6, TEAD1, APLN 290 53 19984 6.500975927130774 0.9999999537684278 0.22438360840257682 0.2206422827387459 GOTERM_BP_DIRECT GO:0007163~establishment or maintenance of cell polarity 5 1.4285714285714286 0.0071948570458286705 PARD6B, FSCN1, FAT1, RND3, RND1 290 53 19984 6.500975927130774 0.9999999537684278 0.22438360840257682 0.2206422827387459 GOTERM_BP_DIRECT GO:0006874~cellular calcium ion homeostasis 7 2.0 0.007421135479495144 EDN1, SLC24A3, STC2, STC1, CCL2, PIK3CB, ATF4 290 118 19984 4.087901811805961 0.999999972873765 0.22796817966960833 0.2241670856092771 GOTERM_BP_DIRECT GO:0030224~monocyte differentiation 4 1.1428571428571428 0.007504724170397538 BMP4, CSF1, FASN, IL31RA 290 28 19984 9.844334975369458 0.999999977723834 0.22796817966960833 0.2241670856092771 GOTERM_BP_DIRECT GO:0045907~positive regulation of vasoconstriction 5 1.4285714285714286 0.007683820299864097 TBXA2R, ADRA1D, HMGCR, SMAD6, MGLL 290 54 19984 6.380587484035759 0.999999985394388 0.23041609847925798 0.22657418832932594 GOTERM_BP_DIRECT GO:0003073~regulation of systemic arterial blood pressure 4 1.1428571428571428 0.00828237957494129 DDAH1, ADM2, ADM, NCALD 290 29 19984 9.50487514863258 0.9999999964387588 0.24373632028338166 0.23967231152277804 GOTERM_BP_DIRECT GO:0030036~actin cytoskeleton organization 9 2.571428571428571 0.008336428226879236 SPTA1, EPB41L5, NUAK2, ROCK2, FSCN1, SPIRE2, SHROOM3, AMOTL2, AMOT 290 198 19984 3.1322884012539185 0.9999999968649972 0.24373632028338166 0.23967231152277804 GOTERM_BP_DIRECT GO:0070374~positive regulation of ERK1 and ERK2 cascade 10 2.857142857142857 0.008484084312255703 BMP4, THPO, FGF18, CCL2, F2RL1, TNFAIP8L3, NRG1, INHBA, HMGCR, FGF21 290 240 19984 2.871264367816092 0.9999999977870351 0.24499102723908756 0.2409060977554089 GOTERM_BP_DIRECT GO:0030334~regulation of cell migration 7 2.0 0.009019082538170107 FGF5, FGF18, AMOTL2, AJUBA, VCL, AMOT, FGF21 290 123 19984 3.921726941407345 0.9999999993737939 0.2572638299607302 0.25297426631452735 GOTERM_BP_DIRECT GO:0043087~regulation of GTPase activity 6 1.7142857142857144 0.009892170575766456 SIPA1L1, DYNLT1C, EPHA1, AJUBA, DGKI, RASGRP3 290 90 19984 4.594022988505747 0.999999999920319 0.2777595796808224 0.2731282741624162 GOTERM_BP_DIRECT GO:1900745~positive regulation of p38MAPK cascade 4 1.1428571428571428 0.009975119578105636 BMP4, GADD45B, GDF6, GADD45G 290 31 19984 8.891657397107897 0.9999999999344988 0.2777595796808224 0.2731282741624162 GOTERM_BP_DIRECT GO:0034976~response to endoplasmic reticulum stress 6 1.7142857142857144 0.010346881163842376 HSPA5, STC2, TRIB3, THBS1, CFTR, ATF4 290 91 19984 4.543539219401288 0.9999999999727898 0.2779194512578703 0.2732854800740067 GOTERM_BP_DIRECT GO:0008543~fibroblast growth factor receptor signaling pathway 5 1.4285714285714286 0.010456140107179388 FGF5, NOG, FGF18, FAT4, FGF21 290 59 19984 5.839859731151373 0.9999999999789826 0.2779194512578703 0.2732854800740067 GOTERM_BP_DIRECT GO:0014823~response to activity 5 1.4285714285714286 0.010456140107179388 EDN1, CCL2, BMP6, AGTR1A, FGF21 290 59 19984 5.839859731151373 0.9999999999789826 0.2779194512578703 0.2732854800740067 GOTERM_BP_DIRECT GO:0006865~amino acid transport 5 1.4285714285714286 0.010456140107179388 SLC7A5, SLC6A9, SLC1A3, SLC1A6, SLC7A1 290 59 19984 5.839859731151373 0.9999999999789826 0.2779194512578703 0.2732854800740067 GOTERM_BP_DIRECT GO:0030282~bone mineralization 5 1.4285714285714286 0.011724255649904798 SMPD3, NFE2, SLC24A3, PKDCC, ATF4 290 61 19984 5.648388920293952 0.999999999998953 0.3046963661192964 0.29961592222077027 GOTERM_BP_DIRECT GO:0050679~positive regulation of epithelial cell proliferation 6 1.7142857142857144 0.011796492440867681 BMP4, OSR1, NOG, BMP6, AZIN1, FOXP2 290 94 19984 4.398532648569332 0.9999999999991175 0.3046963661192964 0.29961592222077027 GOTERM_BP_DIRECT GO:0007631~feeding behavior 4 1.1428571428571428 0.011854369096560912 BDNF, ADM2, HTR1B, APLN 290 33 19984 8.35276907001045 0.9999999999992305 0.3046963661192964 0.29961592222077027 GOTERM_BP_DIRECT GO:0072006~nephron development 3 0.8571428571428572 0.01250052870336007 JAG1, FAT4, DLL1 290 12 19984 17.227586206896554 0.9999999999998334 0.3097018908722331 0.30453798589402997 GOTERM_BP_DIRECT GO:0060272~embryonic skeletal joint morphogenesis 3 0.8571428571428572 0.01250052870336007 BMP4, OSR1, NOG 290 12 19984 17.227586206896554 0.9999999999998334 0.3097018908722331 0.30453798589402997 GOTERM_BP_DIRECT GO:0061626~pharyngeal arch artery morphogenesis 3 0.8571428571428572 0.01250052870336007 BMP4, EDN1, NOG 290 12 19984 17.227586206896554 0.9999999999998334 0.3097018908722331 0.30453798589402997 GOTERM_BP_DIRECT GO:0042127~regulation of cell proliferation 9 2.571428571428571 0.012578742895622977 CNN2, SQLE, JAG1, SFRP2, SERPINE1, DHCR7, KLF4, LGR5, TEAD1 290 213 19984 2.911704711024769 0.9999999999998616 0.3097018908722331 0.30453798589402997 GOTERM_BP_DIRECT GO:0007156~homophilic cell adhesion via plasma membrane adhesion molecules 8 2.2857142857142856 0.012751568940937083 RET, CDH6, CDH3, PCDH10, FAT1, PIK3CB, CDH26, FAT4 290 172 19984 3.2051323175621493 0.9999999999999081 0.31021814985326485 0.3050456368800809 GOTERM_BP_DIRECT GO:0031032~actomyosin structure organization 4 1.1428571428571428 0.012864968164072977 CNN2, EPB41L5, LIMCH1, ROCK2 290 34 19984 8.10709939148073 0.9999999999999297 0.31021814985326485 0.3050456368800809 GOTERM_BP_DIRECT GO:0008283~cell proliferation 12 3.428571428571429 0.013166111675799829 FGF5, BMP4, NFE2, IL11, CSF1, THPO, CITED2, NOG, FGF18, NRG1, ADM, LRP2 290 349 19984 2.3694101373382077 0.9999999999999656 0.3142401552009776 0.30900058014632253 GOTERM_BP_DIRECT GO:0042149~cellular response to glucose starvation 5 1.4285714285714286 0.013804768071406447 NUAK1, NUAK2, HSPA5, ASNS, ATF4 290 64 19984 5.383620689655173 0.9999999999999925 0.32615507594969373 0.32071683398217 GOTERM_BP_DIRECT GO:0030324~lung development 7 2.0 0.01430154208704764 SMPD3, BMP4, FGF18, DHCR7, ZFPM2, CFTR, FOXP2 290 136 19984 3.5468559837728195 0.9999999999999977 0.3345130694160443 0.3289354680020957 GOTERM_BP_DIRECT GO:0006869~lipid transport 8 2.2857142857142856 0.014715880888346687 STARD4, APOL6, ABCA4, SLCO2A1, APOBR, TNFAIP8L3, ATP10A, LDLR 290 177 19984 3.1145918566140662 0.9999999999999991 0.3397839626530085 0.33411847546041873 GOTERM_BP_DIRECT GO:0043200~response to amino acid 4 1.1428571428571428 0.015029755210354413 EDN1, SLC1A3, CCL2, ASNS 290 36 19984 7.656704980842911 0.9999999999999996 0.3397839626530085 0.33411847546041873 GOTERM_BP_DIRECT GO:0032967~positive regulation of collagen biosynthetic process 4 1.1428571428571428 0.015029755210354413 BMP4, SERPINE1, CCL2, INHBA 290 36 19984 7.656704980842911 0.9999999999999996 0.3397839626530085 0.33411847546041873 GOTERM_BP_DIRECT GO:0043066~negative regulation of apoptotic process 18 5.142857142857142 0.01510796584690589 TSLP, HSPA5, BDNF, CITED2, HHIP, SIAH2, OSR1, FHL2, ASNS, DHCR24, LRP2, HMGCR, SMAD6, THBS1, BMP4, SH3RF2, NUAK2, CTH 290 654 19984 1.8966149952546665 0.9999999999999997 0.3397839626530085 0.33411847546041873 GOTERM_BP_DIRECT GO:0042476~odontogenesis 4 1.1428571428571428 0.016184461327885875 BMP4, CSF1, OSR1, INHBA 290 37 19984 7.449767008387698 1.0 0.3505134726474543 0.34466908383460665 GOTERM_BP_DIRECT GO:0071526~semaphorin-plexin signaling pathway 4 1.1428571428571428 0.016184461327885875 FARP2, SEMA3D, CRMP1, SEMA3E 290 37 19984 7.449767008387698 1.0 0.3505134726474543 0.34466908383460665 GOTERM_BP_DIRECT GO:0048514~blood vessel morphogenesis 4 1.1428571428571428 0.016184461327885875 EFNB2, EDN1, THBS1, AMOT 290 37 19984 7.449767008387698 1.0 0.3505134726474543 0.34466908383460665 GOTERM_BP_DIRECT GO:0002040~sprouting angiogenesis 4 1.1428571428571428 0.016184461327885875 RSPO3, SEMA3E, THBS1, E2F7 290 37 19984 7.449767008387698 1.0 0.3505134726474543 0.34466908383460665 GOTERM_BP_DIRECT GO:0031274~positive regulation of pseudopodium assembly 3 0.8571428571428572 0.016911147679160944 CDC42EP3, CDC42EP1, F2RL1 290 14 19984 14.766502463054188 1.0 0.35342222863996625 0.3475293398340839 GOTERM_BP_DIRECT GO:0003197~endocardial cushion development 3 0.8571428571428572 0.016911147679160944 BMP4, CITED2, THBS1 290 14 19984 14.766502463054188 1.0 0.35342222863996625 0.3475293398340839 GOTERM_BP_DIRECT GO:1903671~negative regulation of sprouting angiogenesis 3 0.8571428571428572 0.016911147679160944 PIK3CB, THBS1, ADAMTS9 290 14 19984 14.766502463054188 1.0 0.35342222863996625 0.3475293398340839 GOTERM_BP_DIRECT GO:0042475~odontogenesis of dentin-containing tooth 5 1.4285714285714286 0.016923167852790175 BMP4, EDA, FST, ADM, DLL1 290 68 19984 5.0669371196754565 1.0 0.35342222863996625 0.3475293398340839 GOTERM_BP_DIRECT GO:0001958~endochondral ossification 4 1.1428571428571428 0.01738764841341406 SMPD3, BMP4, FGF18, BMP6 290 38 19984 7.253720508166969 1.0 0.3599089348581901 0.3539078880606401 GOTERM_BP_DIRECT GO:0061436~establishment of skin barrier 4 1.1428571428571428 0.01863946861732431 UGCG, CYP26B1, KLF4, CLDN1 290 39 19984 7.067727674624226 1.0 0.3801904300131254 0.37385121377947345 GOTERM_BP_DIRECT GO:0070986~left/right axis specification 3 0.8571428571428572 0.019328678052378895 EPB41L5, CITED2, DLL1 290 15 19984 13.782068965517242 1.0 0.3801904300131254 0.37385121377947345 GOTERM_BP_DIRECT GO:0003184~pulmonary valve morphogenesis 3 0.8571428571428572 0.019328678052378895 BMP4, JAG1, SMAD6 290 15 19984 13.782068965517242 1.0 0.3801904300131254 0.37385121377947345 GOTERM_BP_DIRECT GO:0045176~apical protein localization 3 0.8571428571428572 0.019328678052378895 INSC, SHROOM2, SHROOM3 290 15 19984 13.782068965517242 1.0 0.3801904300131254 0.37385121377947345 GOTERM_BP_DIRECT GO:0071560~cellular response to transforming growth factor beta stimulus 5 1.4285714285714286 0.019528675772968473 EPB41L5, EDN1, SERPINE1, ANKRD1, CLDN1 290 71 19984 4.8528411850412825 1.0 0.3801904300131254 0.37385121377947345 GOTERM_BP_DIRECT GO:0042493~response to drug 11 3.1428571428571432 0.019548152562009723 RET, ADCYAP1R1, CDH3, SFRP2, HMGCS1, BDNF, TBXA2R, SLC1A3, INHBA, ADCY1, THBS1 290 323 19984 2.346791929112843 1.0 0.3801904300131254 0.37385121377947345 GOTERM_BP_DIRECT GO:0071356~cellular response to tumor necrosis factor 7 2.0 0.019608489315586904 SMPD3, EDN1, ANKRD1, CCL2, THBS1, CLDN1, TANK 290 146 19984 3.303920642418517 1.0 0.3801904300131254 0.37385121377947345 GOTERM_BP_DIRECT GO:0090630~activation of GTPase activity 6 1.7142857142857144 0.019667824724920124 SGSM1, SIPA1L1, NTRK3, NEDD9, ARHGAP29, EPHA1 290 107 19984 3.86413148565904 1.0 0.3801904300131254 0.37385121377947345 GOTERM_BP_DIRECT GO:0045595~regulation of cell differentiation 4 1.1428571428571428 0.019940034093250698 BMP4, CEBPD, NRG1, KLF4 290 40 19984 6.891034482758621 1.0 0.38229294872224084 0.3759186755284968 GOTERM_BP_DIRECT GO:0043123~positive regulation of I-kappaB kinase/NF-kappaB signaling 7 2.0 0.020203770856517707 TRIM6, EDA, LURAP1L, CTH, F2RL1, ROR1, AJUBA 290 147 19984 3.281444991789819 1.0 0.3842001628731294 0.3777940891869165 GOTERM_BP_DIRECT GO:0043154~negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 5 1.4285714285714286 0.02044910231970755 SFRP2, SIAH2, DHCR24, KLF4, THBS1 290 72 19984 4.78544061302682 1.0 0.3857294381112577 0.3792978656074787 GOTERM_BP_DIRECT GO:0060976~coronary vasculature development 4 1.1428571428571428 0.02128941848219198 BMP4, LRP2, SMAD6, APLN 290 41 19984 6.722960470984019 1.0 0.3967535446850663 0.3901381585188767 GOTERM_BP_DIRECT GO:0008285~negative regulation of cell proliferation 13 3.7142857142857144 0.021727512075196548 NFE2, DHCR24, ADM, INHBA, SMAD6, KLF4, THBS1, DLL1, BMP4, SFRP2, DDAH1, CTH, E2F7 290 426 19984 2.102897846851222 1.0 0.3967535446850663 0.3901381585188767 GOTERM_BP_DIRECT GO:0030194~positive regulation of blood coagulation 3 0.8571428571428572 0.021881661934319604 TBXA2R, SERPINE1, THBS1 290 16 19984 12.920689655172415 1.0 0.3967535446850663 0.3901381585188767 GOTERM_BP_DIRECT GO:0090051~negative regulation of cell migration involved in sprouting angiogenesis 3 0.8571428571428572 0.021881661934319604 TBXA2R, KLF4, THBS1 290 16 19984 12.920689655172415 1.0 0.3967535446850663 0.3901381585188767 GOTERM_BP_DIRECT GO:0042756~drinking behavior 3 0.8571428571428572 0.021881661934319604 HTR1B, AGTR1A, APLN 290 16 19984 12.920689655172415 1.0 0.3967535446850663 0.3901381585188767 GOTERM_BP_DIRECT GO:0042472~inner ear morphogenesis 5 1.4285714285714286 0.022368940133723123 PTPRQ, INSIG1, HOXA1, EPHB2, DLL1 290 74 19984 4.656104380242311 1.0 0.3993965723112854 0.3927371168516273 GOTERM_BP_DIRECT GO:0006633~fatty acid biosynthetic process 5 1.4285714285714286 0.022368940133723123 FADS3, FASN, ELOVL6, ACSL3, MGLL 290 74 19984 4.656104380242311 1.0 0.3993965723112854 0.3927371168516273 GOTERM_BP_DIRECT GO:0030857~negative regulation of epithelial cell differentiation 3 0.8571428571428572 0.024565704444283996 FST, OSR1, DLL1 290 17 19984 12.160649087221095 1.0 0.4194100926655494 0.4124169359259357 GOTERM_BP_DIRECT GO:0043116~negative regulation of vascular permeability 3 0.8571428571428572 0.024565704444283996 DDAH1, ADM, AMOT 290 17 19984 12.160649087221095 1.0 0.4194100926655494 0.4124169359259357 GOTERM_BP_DIRECT GO:0002089~lens morphogenesis in camera-type eye 3 0.8571428571428572 0.024565704444283996 CITED2, SHROOM2, SOX11 290 17 19984 12.160649087221095 1.0 0.4194100926655494 0.4124169359259357 GOTERM_BP_DIRECT GO:0071372~cellular response to follicle-stimulating hormone stimulus 3 0.8571428571428572 0.024565704444283996 EDN1, HMGCS1, INHBA 290 17 19984 12.160649087221095 1.0 0.4194100926655494 0.4124169359259357 GOTERM_BP_DIRECT GO:0008299~isoprenoid biosynthetic process 3 0.8571428571428572 0.024565704444283996 IDI1, HMGCS1, HMGCR 290 17 19984 12.160649087221095 1.0 0.4194100926655494 0.4124169359259357 GOTERM_BP_DIRECT GO:0015813~L-glutamate transport 3 0.8571428571428572 0.024565704444283996 SLC1A3, SLC1A4, SLC1A6 290 17 19984 12.160649087221095 1.0 0.4194100926655494 0.4124169359259357 GOTERM_BP_DIRECT GO:0006469~negative regulation of protein kinase activity 5 1.4285714285714286 0.026528926072637755 GADD45B, TRIB3, EPHB2, EPHA1, GADD45G 290 78 19984 4.417329796640141 1.0 0.449646073071737 0.44214876787729596 GOTERM_BP_DIRECT GO:0001655~urogenital system development 3 0.8571428571428572 0.027376508715592045 OSR1, NOG, EPHB2 290 18 19984 11.485057471264367 1.0 0.4573832420412128 0.44975692889901214 GOTERM_BP_DIRECT GO:0003323~type B pancreatic cell development 3 0.8571428571428572 0.027376508715592045 BMP4, DLL1, BMP6 290 18 19984 11.485057471264367 1.0 0.4573832420412128 0.44975692889901214 GOTERM_BP_DIRECT GO:0043482~cellular pigment accumulation 2 0.5714285714285714 0.028714714753092237 SHROOM2, SHROOM3 290 2 19984 68.91034482758621 1.0 0.46733200895579974 0.45953981214123096 GOTERM_BP_DIRECT GO:2000134~negative regulation of G1/S transition of mitotic cell cycle 4 1.1428571428571428 0.0287686834854159 CCL2, INHBA, KLF4, E2F7 290 46 19984 5.992203898050974 1.0 0.46733200895579974 0.45953981214123096 GOTERM_BP_DIRECT GO:0060412~ventricular septum morphogenesis 4 1.1428571428571428 0.0287686834854159 CITED2, NOG, SOX11, ZFPM2 290 46 19984 5.992203898050974 1.0 0.46733200895579974 0.45953981214123096 GOTERM_BP_DIRECT GO:0007267~cell-cell signaling 5 1.4285714285714286 0.028771188238407505 NFE2, EDN1, WNT2B, ADRA1D, DLL1 290 80 19984 4.306896551724138 1.0 0.46733200895579974 0.45953981214123096 GOTERM_BP_DIRECT GO:0043010~camera-type eye development 5 1.4285714285714286 0.029933266247678118 BMP4, JAG1, FAT1, SHROOM2, FOXP2 290 81 19984 4.253724989357174 1.0 0.47420180290236663 0.4662950605709462 GOTERM_BP_DIRECT GO:0060021~palate development 5 1.4285714285714286 0.029933266247678118 PKDCC, INSIG1, OSR1, INHBA, EPHB2 290 81 19984 4.253724989357174 1.0 0.47420180290236663 0.4662950605709462 GOTERM_BP_DIRECT GO:0060044~negative regulation of cardiac muscle cell proliferation 3 0.8571428571428572 0.03030987399605328 CXADR, CITED2, NOG 290 19 19984 10.880580762250453 1.0 0.47420180290236663 0.4662950605709462 GOTERM_BP_DIRECT GO:0001953~negative regulation of cell-matrix adhesion 3 0.8571428571428572 0.03030987399605328 JAG1, SEMA3E, THBS1 290 19 19984 10.880580762250453 1.0 0.47420180290236663 0.4662950605709462 GOTERM_BP_DIRECT GO:0019229~regulation of vasoconstriction 3 0.8571428571428572 0.03030987399605328 EDN1, TBXA2R, AGTR1A 290 19 19984 10.880580762250453 1.0 0.47420180290236663 0.4662950605709462 GOTERM_BP_DIRECT GO:0030501~positive regulation of bone mineralization 4 1.1428571428571428 0.03041054742853997 BMP4, PKDCC, OSR1, BMP6 290 47 19984 5.864710198092443 1.0 0.47420180290236663 0.4662950605709462 GOTERM_BP_DIRECT GO:0071347~cellular response to interleukin-1 5 1.4285714285714286 0.031122759235204654 EDN1, SERPINE1, ANKRD1, CCL2, TANK 290 82 19984 4.201850294365013 1.0 0.48209360166320325 0.4740552731190113 GOTERM_BP_DIRECT GO:0055074~calcium ion homeostasis 4 1.1428571428571428 0.03210078346288299 JPH2, STC2, ADM, FAM20A 290 48 19984 5.742528735632185 1.0 0.4938896794893647 0.4856546655945014 GOTERM_BP_DIRECT GO:0098609~cell-cell adhesion 8 2.2857142857142856 0.03230659297215596 CDH6, CDH3, DLG2, CXADR, FAT1, CNTN2, CDH26, FAT4 290 208 19984 2.650397877984085 1.0 0.4938896794893647 0.4856546655945014 GOTERM_BP_DIRECT GO:0042177~negative regulation of protein catabolic process 4 1.1428571428571428 0.0338392057927637 NRG1, HMGCR, AZIN1, CYP51 290 49 19984 5.62533427163969 1.0 0.5139604048654175 0.5053907358659513 GOTERM_BP_DIRECT GO:0035725~sodium ion transmembrane transport 5 1.4285714285714286 0.03615623181801282 SLC24A3, SLC6A9, OSR1, SCN7A, CFTR 290 86 19984 4.006415396952686 1.0 0.5456092014344 0.5365118269769644 GOTERM_BP_DIRECT GO:0048661~positive regulation of smooth muscle cell proliferation 5 1.4285714285714286 0.03883893690815292 SMPD3, BMP4, EDN1, HMGCR, THBS1 290 88 19984 3.915360501567398 1.0 0.578281156766571 0.5686390169145418 GOTERM_BP_DIRECT GO:0045429~positive regulation of nitric oxide biosynthetic process 4 1.1428571428571428 0.039341336196955276 SMPD3, DDAH1, PTX3, KLF4 290 52 19984 5.30079575596817 1.0 0.578281156766571 0.5686390169145418 GOTERM_BP_DIRECT GO:0048646~anatomical structure formation involved in morphogenesis 3 0.8571428571428572 0.03980473118401792 BMP4, NOG, HOXA1 290 22 19984 9.396865203761756 1.0 0.578281156766571 0.5686390169145418 GOTERM_BP_DIRECT GO:0090280~positive regulation of calcium ion import 3 0.8571428571428572 0.03980473118401792 SERPINE1, STC1, CCL2 290 22 19984 9.396865203761756 1.0 0.578281156766571 0.5686390169145418 GOTERM_BP_DIRECT GO:0050709~negative regulation of protein secretion 3 0.8571428571428572 0.03980473118401792 FRMD4A, HMGCR, CYP51 290 22 19984 9.396865203761756 1.0 0.578281156766571 0.5686390169145418 GOTERM_BP_DIRECT GO:0045197~establishment or maintenance of epithelial cell apical/basal polarity 3 0.8571428571428572 0.03980473118401792 PRKCI, DLG2, FAT1 290 22 19984 9.396865203761756 1.0 0.578281156766571 0.5686390169145418 GOTERM_BP_DIRECT GO:0006931~substrate-dependent cell migration, cell attachment to substrate 2 0.5714285714285714 0.04276243006889522 EPB41L5, TNFRSF12A 290 3 19984 45.94022988505748 1.0 0.5915315943471248 0.581668519452068 GOTERM_BP_DIRECT GO:0003365~establishment of cell polarity involved in ameboidal cell migration 2 0.5714285714285714 0.04276243006889522 AMOTL2, AMOT 290 3 19984 45.94022988505748 1.0 0.5915315943471248 0.581668519452068 GOTERM_BP_DIRECT GO:0072070~loop of Henle development 2 0.5714285714285714 0.04276243006889522 JAG1, DLL1 290 3 19984 45.94022988505748 1.0 0.5915315943471248 0.581668519452068 GOTERM_BP_DIRECT GO:1904782~negative regulation of NMDA glutamate receptor activity 2 0.5714285714285714 0.04276243006889522 SLC6A9, EPHB2 290 3 19984 45.94022988505748 1.0 0.5915315943471248 0.581668519452068 GOTERM_BP_DIRECT GO:0007204~positive regulation of cytosolic calcium ion concentration 7 2.0 0.04312106346075323 JPH2, EDN1, TBXA2R, F2RL1, ADRA1D, ADM, AGTR1A 290 176 19984 2.7407523510971785 1.0 0.5915315943471248 0.581668519452068 GOTERM_BP_DIRECT GO:0002063~chondrocyte development 3 0.8571428571428572 0.043188190715097004 SMPD3, SFRP2, FGF18 290 23 19984 8.988305847076461 1.0 0.5915315943471248 0.581668519452068 GOTERM_BP_DIRECT GO:0007422~peripheral nervous system development 3 0.8571428571428572 0.043188190715097004 BDNF, CITED2, NRG1 290 23 19984 8.988305847076461 1.0 0.5915315943471248 0.581668519452068 GOTERM_BP_DIRECT GO:0022011~myelination in peripheral nervous system 3 0.8571428571428572 0.043188190715097004 SH3TC2, NTRK3, NRG1 290 23 19984 8.988305847076461 1.0 0.5915315943471248 0.581668519452068 GOTERM_BP_DIRECT GO:0001934~positive regulation of protein phosphorylation 9 2.571428571428571 0.043237014166418924 FGF5, BMP4, THPO, LIMCH1, ROCK2, FGF18, FAM20A, INHBA, FGF21 290 270 19984 2.2970114942528737 1.0 0.5915315943471248 0.581668519452068 GOTERM_BP_DIRECT GO:0009953~dorsal/ventral pattern formation 4 1.1428571428571428 0.04324578992447984 EDN1, HHIP, NOG, TLL1 290 54 19984 5.104469987228607 1.0 0.5915315943471248 0.581668519452068 GOTERM_BP_DIRECT GO:0010596~negative regulation of endothelial cell migration 3 0.8571428571428572 0.04667458510203725 STC1, THBS1, ADAMTS9 290 24 19984 8.613793103448277 1.0 0.6274244514578455 0.6169629065211821 GOTERM_BP_DIRECT GO:0071404~cellular response to low-density lipoprotein particle stimulus 3 0.8571428571428572 0.04667458510203725 HMGCS1, LDLR, FGF21 290 24 19984 8.613793103448277 1.0 0.6274244514578455 0.6169629065211821 GOTERM_BP_DIRECT GO:0006939~smooth muscle contraction 3 0.8571428571428572 0.04667458510203725 EDN1, ROCK2, TBXA2R 290 24 19984 8.613793103448277 1.0 0.6274244514578455 0.6169629065211821 GOTERM_BP_DIRECT GO:0048286~lung alveolus development 4 1.1428571428571428 0.04733640484645657 SMPD3, BMP4, PKDCC, FOXP2 290 56 19984 4.922167487684729 1.0 0.6326848624906396 0.6221356065534291 GOTERM_BP_DIRECT GO:0030968~endoplasmic reticulum unfolded protein response 4 1.1428571428571428 0.04945063242403152 HSPA5, STC2, ATF4, FGF21 290 57 19984 4.835813672111312 1.0 0.6571876661352825 0.646229855541321 GOTERM_BP_DIRECT GO:0010759~positive regulation of macrophage chemotaxis 3 0.8571428571428572 0.05026025226905109 CSF1, CCL2, THBS1 290 25 19984 8.269241379310344 1.0 0.659652875351242 0.6486539603710374 GOTERM_BP_DIRECT GO:0008584~male gonad development 6 1.7142857142857144 0.05033537360960361 WNT2B, SFRP2, HMGCS1, CITED2, INHBA, LRP2 290 138 19984 2.9961019490254874 1.0 0.659652875351242 0.6486539603710374 GOTERM_BP_DIRECT GO:0045444~fat cell differentiation 5 1.4285714285714286 0.05067846569100304 CEBPD, CNTN2, KLF4, SMAD6, GDF6 290 96 19984 3.589080459770115 1.0 0.659652875351242 0.6486539603710374 GOTERM_BP_DIRECT GO:0045599~negative regulation of fat cell differentiation 4 1.1428571428571428 0.0516102933686521 JAG1, INSIG1, TRIB3, ZFPM2 290 58 19984 4.75243757431629 1.0 0.659652875351242 0.6486539603710374 GOTERM_BP_DIRECT GO:0006936~muscle contraction 4 1.1428571428571428 0.0516102933686521 TPM1, LMOD1, SCN7A, MYOM2 290 58 19984 4.75243757431629 1.0 0.659652875351242 0.6486539603710374 GOTERM_BP_DIRECT GO:0030514~negative regulation of BMP signaling pathway 4 1.1428571428571428 0.0516102933686521 SFRP2, NOG, LRP2, SMAD6 290 58 19984 4.75243757431629 1.0 0.659652875351242 0.6486539603710374 GOTERM_BP_DIRECT GO:0051496~positive regulation of stress fiber assembly 4 1.1428571428571428 0.0516102933686521 LIMCH1, ROCK2, TPM1, EPHA1 290 58 19984 4.75243757431629 1.0 0.659652875351242 0.6486539603710374 GOTERM_BP_DIRECT GO:0007266~Rho protein signal transduction 4 1.1428571428571428 0.05381498014843432 ROCK2, CDC42EP3, CDC42EP1, AGTR1A 290 59 19984 4.671887784921099 1.0 0.6819969451885503 0.6706254698305539 GOTERM_BP_DIRECT GO:0015012~heparan sulfate proteoglycan biosynthetic process 3 0.8571428571428572 0.053941613877674995 HS3ST3B1, HS6ST2, HS6ST3 290 26 19984 7.951193633952254 1.0 0.6819969451885503 0.6706254698305539 GOTERM_BP_DIRECT GO:0006564~L-serine biosynthetic process 2 0.5714285714285714 0.056607665930954114 PSAT1, PSPH 290 4 19984 34.45517241379311 1.0 0.6994600583842496 0.6877974067053331 GOTERM_BP_DIRECT GO:1900037~regulation of cellular response to hypoxia 2 0.5714285714285714 0.056607665930954114 ROCK2, AJUBA 290 4 19984 34.45517241379311 1.0 0.6994600583842496 0.6877974067053331 GOTERM_BP_DIRECT GO:0042305~specification of segmental identity, mandibular segment 2 0.5714285714285714 0.056607665930954114 BMP4, NOG 290 4 19984 34.45517241379311 1.0 0.6994600583842496 0.6877974067053331 GOTERM_BP_DIRECT GO:0001839~neural plate morphogenesis 2 0.5714285714285714 0.056607665930954114 EPB41L5, NOG 290 4 19984 34.45517241379311 1.0 0.6994600583842496 0.6877974067053331 GOTERM_BP_DIRECT GO:0046579~positive regulation of Ras protein signal transduction 3 0.8571428571428572 0.05771517369309969 CSF1, NRG1, DGKI 290 27 19984 7.656704980842911 1.0 0.6994600583842496 0.6877974067053331 GOTERM_BP_DIRECT GO:0097150~neuronal stem cell population maintenance 3 0.8571428571428572 0.05771517369309969 JAG1, IGF2BP1, DLL1 290 27 19984 7.656704980842911 1.0 0.6994600583842496 0.6877974067053331 GOTERM_BP_DIRECT GO:0060425~lung morphogenesis 3 0.8571428571428572 0.05771517369309969 BMP4, NOG, SOX11 290 27 19984 7.656704980842911 1.0 0.6994600583842496 0.6877974067053331 GOTERM_BP_DIRECT GO:0007205~protein kinase C-activating G-protein coupled receptor signaling pathway 3 0.8571428571428572 0.05771517369309969 EDN1, HTR1B, DGKI 290 27 19984 7.656704980842911 1.0 0.6994600583842496 0.6877974067053331 GOTERM_BP_DIRECT GO:0032496~response to lipopolysaccharide 7 2.0 0.058383002665813526 TRIM6, EDN1, HPGD, TBXA2R, ADM, SMAD6, CLDN1 290 190 19984 2.538802177858439 1.0 0.7039064084295764 0.6921696192338718 GOTERM_BP_DIRECT GO:0009966~regulation of signal transduction 4 1.1428571428571428 0.06069487107422935 UGCG, LURAP1L, VEPH1, MGLL 290 62 19984 4.445828698553949 1.0 0.717233176698621 0.7052741797378487 GOTERM_BP_DIRECT GO:0045944~positive regulation of transcription from RNA polymerase II promoter 26 7.428571428571429 0.06070763803196025 CEBPD, CITED2, GLIS3, IKZF2, DLL1, HOXA1, TEAD1, E2F7, TEAD3, IL11, EDN1, JAG1, OSR1, NOG, EBF3, SOX11, INHBA, KLF4, BMP6, SGSM1, BMP4, BMP3, SFRP2, F2RL1, ZFPM2, ATF4 290 1245 19984 1.4390915385680654 1.0 0.717233176698621 0.7052741797378487 GOTERM_BP_DIRECT GO:0042632~cholesterol homeostasis 5 1.4285714285714286 0.06071490764699741 GPR39, SOAT2, INSIG1, HMGCR, LDLR 290 102 19984 3.3779580797836375 1.0 0.717233176698621 0.7052741797378487 GOTERM_BP_DIRECT GO:0001649~osteoblast differentiation 5 1.4285714285714286 0.06071490764699741 BMP4, BMP3, NOG, FHL2, BMP6 290 102 19984 3.3779580797836375 1.0 0.717233176698621 0.7052741797378487 GOTERM_BP_DIRECT GO:0035556~intracellular signal transduction 12 3.428571428571429 0.0611319085869409 PRKCI, NUAK1, EDN1, NUAK2, ROCK2, ARHGAP29, NRG1, ADCY1, ASB5, PAK3, DGKI, ASB15 290 447 19984 1.8499421430224485 1.0 0.7185303225369586 0.7065496972360004 GOTERM_BP_DIRECT GO:0071398~cellular response to fatty acid 3 0.8571428571428572 0.061577515965071085 EDN1, CCL2, LDLR 290 28 19984 7.383251231527094 1.0 0.7201490492115064 0.7081414335983175 GOTERM_BP_DIRECT GO:0033138~positive regulation of peptidyl-serine phosphorylation 5 1.4285714285714286 0.06248284953690949 IL11, TRIM6, SFRP2, BDNF, NTRK3 290 103 19984 3.345162370271175 1.0 0.7267637042261527 0.7146457972296499 GOTERM_BP_DIRECT GO:0043524~negative regulation of neuron apoptotic process 7 2.0 0.06299824873145514 PRKCI, BDNF, CHL1, CCL2, SEMA3E, IL6ST, OXR1 290 194 19984 2.486455741201564 1.0 0.7267637042261527 0.7146457972296499 GOTERM_BP_DIRECT GO:0010595~positive regulation of endothelial cell migration 4 1.1428571428571428 0.06307525949461693 BMP4, ROCK2, PIK3CB, THBS1 290 63 19984 4.3752599890530925 1.0 0.7267637042261527 0.7146457972296499 GOTERM_BP_DIRECT GO:0002931~response to ischemia 4 1.1428571428571428 0.06549839842053595 CSF1, ROCK2, NPR3, PIK3CB 290 64 19984 4.306896551724138 1.0 0.7435409085487884 0.7311432619333961 GOTERM_BP_DIRECT GO:0007249~I-kappaB kinase/NF-kappaB signaling 4 1.1428571428571428 0.06549839842053595 EDN1, ROCK2, TANK, AJUBA 290 64 19984 4.306896551724138 1.0 0.7435409085487884 0.7311432619333961 GOTERM_BP_DIRECT GO:0001701~in utero embryonic development 10 2.857142857142857 0.06608612976561962 EPB41L5, EDN1, ADAMTS3, CITED2, TPM1, NOG, ZFPM2, DLL1, PSPH, AMOT 290 347 19984 1.9858888999304383 1.0 0.7435409085487884 0.7311432619333961 GOTERM_BP_DIRECT GO:0007043~cell-cell junction assembly 3 0.8571428571428572 0.06955527783892684 CDH6, PARD6B, FSCN1 290 30 19984 6.891034482758621 1.0 0.7435409085487884 0.7311432619333961 GOTERM_BP_DIRECT GO:0045216~cell-cell junction organization 3 0.8571428571428572 0.06955527783892684 PRKCI, CXADR, CLDN1 290 30 19984 6.891034482758621 1.0 0.7435409085487884 0.7311432619333961 GOTERM_BP_DIRECT GO:0002158~osteoclast proliferation 2 0.5714285714285714 0.07025333082055675 CSF1, NPR3 290 5 19984 27.564137931034484 1.0 0.7435409085487884 0.7311432619333961 GOTERM_BP_DIRECT GO:0035089~establishment of apical/basal cell polarity 2 0.5714285714285714 0.07025333082055675 PRKCI, FSCN1 290 5 19984 27.564137931034484 1.0 0.7435409085487884 0.7311432619333961 GOTERM_BP_DIRECT GO:0060502~epithelial cell proliferation involved in lung morphogenesis 2 0.5714285714285714 0.07025333082055675 BMP4, FOXP2 290 5 19984 27.564137931034484 1.0 0.7435409085487884 0.7311432619333961 GOTERM_BP_DIRECT GO:0060363~cranial suture morphogenesis 2 0.5714285714285714 0.07025333082055675 BMP4, INSIG1 290 5 19984 27.564137931034484 1.0 0.7435409085487884 0.7311432619333961 GOTERM_BP_DIRECT GO:0061035~regulation of cartilage development 2 0.5714285714285714 0.07025333082055675 SMPD3, BMP4 290 5 19984 27.564137931034484 1.0 0.7435409085487884 0.7311432619333961 GOTERM_BP_DIRECT GO:0035702~monocyte homeostasis 2 0.5714285714285714 0.07025333082055675 CSF1, CCL2 290 5 19984 27.564137931034484 1.0 0.7435409085487884 0.7311432619333961 GOTERM_BP_DIRECT GO:0046545~development of primary female sexual characteristics 2 0.5714285714285714 0.07025333082055675 ADCYAP1R1, DACH2 290 5 19984 27.564137931034484 1.0 0.7435409085487884 0.7311432619333961 GOTERM_BP_DIRECT GO:1990791~dorsal root ganglion development 2 0.5714285714285714 0.07025333082055675 RGS4, TUBB3 290 5 19984 27.564137931034484 1.0 0.7435409085487884 0.7311432619333961 GOTERM_BP_DIRECT GO:1905460~negative regulation of vascular associated smooth muscle cell apoptotic process 2 0.5714285714285714 0.07025333082055675 SLC7A5, CFTR 290 5 19984 27.564137931034484 1.0 0.7435409085487884 0.7311432619333961 GOTERM_BP_DIRECT GO:0002085~inhibition of neuroepithelial cell differentiation 2 0.5714285714285714 0.07025333082055675 JAG1, DLL1 290 5 19984 27.564137931034484 1.0 0.7435409085487884 0.7311432619333961 GOTERM_BP_DIRECT GO:0015015~heparan sulfate proteoglycan biosynthetic process, enzymatic modification 2 0.5714285714285714 0.07025333082055675 HS6ST2, HS6ST3 290 5 19984 27.564137931034484 1.0 0.7435409085487884 0.7311432619333961 GOTERM_BP_DIRECT GO:0060513~prostatic bud formation 2 0.5714285714285714 0.07025333082055675 BMP4, NOG 290 5 19984 27.564137931034484 1.0 0.7435409085487884 0.7311432619333961 GOTERM_BP_DIRECT GO:0034435~cholesterol esterification 2 0.5714285714285714 0.07025333082055675 STARD4, SOAT2 290 5 19984 27.564137931034484 1.0 0.7435409085487884 0.7311432619333961 GOTERM_BP_DIRECT GO:0048511~rhythmic process 6 1.7142857142857144 0.07169306062049516 ROCK2, SIAH2, ADCY1, ENOX1, ATF4, CIART 290 153 19984 2.7023664638269103 1.0 0.755360670231253 0.7427659433654904 GOTERM_BP_DIRECT GO:0048168~regulation of neuronal synaptic plasticity 3 0.8571428571428572 0.07366425427299027 NOG, CNTN2, EPHB2 290 31 19984 6.668743047830923 1.0 0.7726488374193912 0.759765851246088 GOTERM_BP_DIRECT GO:0000187~activation of MAPK activity 4 1.1428571428571428 0.07560833900576189 RET, NTRK3, NRG1, THBS1 290 68 19984 4.053549695740365 1.0 0.7825128536923763 0.7694653969612935 GOTERM_BP_DIRECT GO:0042733~embryonic digit morphogenesis 4 1.1428571428571428 0.07560833900576189 BMP4, SFRP2, OSR1, NOG 290 68 19984 4.053549695740365 1.0 0.7825128536923763 0.7694653969612935 GOTERM_BP_DIRECT GO:0002062~chondrocyte differentiation 4 1.1428571428571428 0.07560833900576189 BMP4, WNT2B, OSR1, FGF18 290 68 19984 4.053549695740365 1.0 0.7825128536923763 0.7694653969612935 GOTERM_BP_DIRECT GO:0090263~positive regulation of canonical Wnt signaling pathway 5 1.4285714285714286 0.07758535191876051 CDH3, EDA, SFRP2, RSPO3, LGR5 290 111 19984 3.1040695868282078 1.0 0.7882645045271469 0.7751211459651295 GOTERM_BP_DIRECT GO:0045666~positive regulation of neuron differentiation 5 1.4285714285714286 0.07758535191876051 BMP4, BDNF, SOX11, GDF6, BMP6 290 111 19984 3.1040695868282078 1.0 0.7882645045271469 0.7751211459651295 GOTERM_BP_DIRECT GO:0042060~wound healing 5 1.4285714285714286 0.07758535191876051 CNN2, CDH3, TPM1, NOG, NRG1 290 111 19984 3.1040695868282078 1.0 0.7882645045271469 0.7751211459651295 GOTERM_BP_DIRECT GO:0048013~ephrin receptor signaling pathway 3 0.8571428571428572 0.07784912379041083 EFNB2, SIPA1L1, EPHB2 290 32 19984 6.460344827586208 1.0 0.7882645045271469 0.7751211459651295 GOTERM_BP_DIRECT GO:0046697~decidualization 3 0.8571428571428572 0.07784912379041083 CITED2, STC2, STC1 290 32 19984 6.460344827586208 1.0 0.7882645045271469 0.7751211459651295 GOTERM_BP_DIRECT GO:0051649~establishment of localization in cell 7 2.0 0.07933264833207809 CNN2, GPR39, CACNA1B, CNTN2, SLC1A6, LDLR, CFTR 290 206 19984 2.3416136591898224 1.0 0.7998235536583219 0.7864874619128431 GOTERM_BP_DIRECT GO:0032869~cellular response to insulin stimulus 5 1.4285714285714286 0.08367885022587088 PRKCI, INSIG1, PNPLA3, CCL2, TRIB3 290 114 19984 3.0223835450695704 1.0 0.8191617575490395 0.8055032246100005 GOTERM_BP_DIRECT GO:0046985~positive regulation of hemoglobin biosynthetic process 2 0.5714285714285714 0.0837022916007783 SLC6A9, KLF4 290 6 19984 22.97011494252874 1.0 0.8191617575490395 0.8055032246100005 GOTERM_BP_DIRECT GO:0010825~positive regulation of centrosome duplication 2 0.5714285714285714 0.0837022916007783 ROCK2, AZIN1 290 6 19984 22.97011494252874 1.0 0.8191617575490395 0.8055032246100005 GOTERM_BP_DIRECT GO:0003357~noradrenergic neuron differentiation 2 0.5714285714285714 0.0837022916007783 EDN1, SOX11 290 6 19984 22.97011494252874 1.0 0.8191617575490395 0.8055032246100005 GOTERM_BP_DIRECT GO:0045163~clustering of voltage-gated potassium channels 2 0.5714285714285714 0.0837022916007783 DLG2, CNTN2 290 6 19984 22.97011494252874 1.0 0.8191617575490395 0.8055032246100005 GOTERM_BP_DIRECT GO:0097187~dentinogenesis 2 0.5714285714285714 0.0837022916007783 SMPD3, SERPINE1 290 6 19984 22.97011494252874 1.0 0.8191617575490395 0.8055032246100005 GOTERM_BP_DIRECT GO:0070447~positive regulation of oligodendrocyte progenitor proliferation 2 0.5714285714285714 0.0837022916007783 NOG, LRP2 290 6 19984 22.97011494252874 1.0 0.8191617575490395 0.8055032246100005 GOTERM_BP_DIRECT GO:0009653~anatomical structure morphogenesis 4 1.1428571428571428 0.08636048635949896 RET, HOXA1, SOX11, SMAD6 290 72 19984 3.8283524904214556 1.0 0.8285664733792422 0.8147511281625724 GOTERM_BP_DIRECT GO:0007140~male meiosis 3 0.8571428571428572 0.08643446750942073 TDRKH, CYP26B1, DDX4 290 34 19984 6.080324543610548 1.0 0.8285664733792422 0.8147511281625724 GOTERM_BP_DIRECT GO:0006418~tRNA aminoacylation for protein translation 3 0.8571428571428572 0.08643446750942073 TARS, GARS, IARS 290 34 19984 6.080324543610548 1.0 0.8285664733792422 0.8147511281625724 GOTERM_BP_DIRECT GO:0001954~positive regulation of cell-matrix adhesion 3 0.8571428571428572 0.08643446750942073 EPB41L5, CSF1, EPHA1 290 34 19984 6.080324543610548 1.0 0.8285664733792422 0.8147511281625724 GOTERM_BP_DIRECT GO:1904706~negative regulation of vascular smooth muscle cell proliferation 3 0.8571428571428572 0.08643446750942073 TPM1, TIMP3, APLN 290 34 19984 6.080324543610548 1.0 0.8285664733792422 0.8147511281625724 GOTERM_BP_DIRECT GO:0019933~cAMP-mediated signaling 3 0.8571428571428572 0.0908290815156897 ADCYAP1R1, ADM, ADCY1 290 35 19984 5.906600985221675 1.0 0.8671396802661152 0.8526811734125973 GOTERM_BP_DIRECT GO:0007584~response to nutrient 4 1.1428571428571428 0.0948244275278342 SFRP2, TBXA2R, ACSL3, HMGCR 290 75 19984 3.6752183908045977 1.0 0.8963766717801079 0.8814306734049802 GOTERM_BP_DIRECT GO:0006468~protein phosphorylation 15 4.285714285714286 0.09662867489041971 RET, PRKCI, EDN1, PKDCC, ROCK2, NTRK3, NUAK1, NUAK2, ADM2, ROR1, TRIB3, FAM20A, EPHA1, PAK3, EPHB2 290 654 19984 1.5805124960455552 1.0 0.8963766717801079 0.8814306734049802 GOTERM_BP_DIRECT GO:0044691~tooth eruption 2 0.5714285714285714 0.09695737407454781 ADAMTS5, FAM20A 290 7 19984 19.688669950738916 1.0 0.8963766717801079 0.8814306734049802 GOTERM_BP_DIRECT GO:0030072~peptide hormone secretion 2 0.5714285714285714 0.09695737407454781 SMPD3, EDN1 290 7 19984 19.688669950738916 1.0 0.8963766717801079 0.8814306734049802 GOTERM_BP_DIRECT GO:0042490~mechanoreceptor differentiation 2 0.5714285714285714 0.09695737407454781 BDNF, NTRK3 290 7 19984 19.688669950738916 1.0 0.8963766717801079 0.8814306734049802 GOTERM_BP_DIRECT GO:0050878~regulation of body fluid levels 2 0.5714285714285714 0.09695737407454781 EPHB2, APLN 290 7 19984 19.688669950738916 1.0 0.8963766717801079 0.8814306734049802 GOTERM_BP_DIRECT GO:0001957~intramembranous ossification 2 0.5714285714285714 0.09695737407454781 MN1, FGF18 290 7 19984 19.688669950738916 1.0 0.8963766717801079 0.8814306734049802 GOTERM_BP_DIRECT GO:0070508~cholesterol import 2 0.5714285714285714 0.09695737407454781 STARD4, LDLR 290 7 19984 19.688669950738916 1.0 0.8963766717801079 0.8814306734049802 GOTERM_BP_DIRECT GO:0010259~multicellular organism aging 3 0.8571428571428572 0.0998080599364719 EDN1, ADRA1D, AGTR1A 290 37 19984 5.587325256290773 1.0 0.9190986306748339 0.9037737710782889