Table S4: The differentially expressed genes (DEGs) in TCGA-UVM cohort.,,,,,,, ,logFC,AveExpr,t,P.Value,adj.P.Val,B,change SYBU,1.64228992,2.56690191,3.501090285,0.00076785,1,-0.698298696,UP AVEN,1.388874527,6.241885866,3.41082563,0.001026401,1,-0.960521907,UP NUTF2,4.917839532,27.391825,3.171564766,0.002164674,1,-1.630973625,UP HIST3H2A,22.21856399,68.200106,3.032182351,0.003290342,1,-2.004394204,UP ZNF32,3.824991757,17.45380173,3.013477828,0.003477317,1,-2.053512586,UP PTMA,26.87436086,159.2988693,2.937254711,0.004345756,1,-2.251200029,UP HSBP1,1.765577932,8.405110332,2.895135444,0.004907668,1,-2.358714147,UP DCTN2,3.996297694,34.8200935,2.872203278,0.00524106,1,-2.416729555,UP TMEM261,1.882918981,13.54607716,2.787948679,0.006652978,1,-2.626689995,UP AMFR,4.742096074,18.96923314,2.774512441,0.006907964,1,-2.65970456,UP SEMA6D,1.009290818,1.42603699,2.758627544,0.007220946,1,-2.698568263,UP KCTD10,0.668641981,4.523154907,2.756632226,0.007261164,1,-2.703437108,UP CYB5B,1.805078277,11.31987335,2.756335954,0.007267153,1,-2.704159809,UP EMC8,0.79997035,6.005556913,2.738931529,0.007627012,1,-2.746503211,UP CA5B,0.519593267,1.114512126,2.730444509,0.007808333,1,-2.767071785,UP BAG3,5.677273566,22.40262485,2.710312468,0.008254289,1,-2.815653088,UP KARS,6.100679298,43.28192941,2.642817594,0.009924076,1,-2.976363441,UP BCAR1,1.377979341,7.349489617,2.570547048,0.012047068,1,-3.144708079,UP PCDHB5,0.822129916,1.180467339,2.567827538,0.012134429,1,-3.150966626,UP SRD5A1,0.638144481,3.485304575,2.566058079,0.012191577,1,-3.155035789,UP GCSH,0.585345766,2.220308972,2.555867313,0.012525465,1,-3.178425325,UP UBE2Q1,2.598034975,24.7171771,2.498121217,0.014578076,1,-3.309480787,UP SGK1,4.417560936,6.860493196,2.479421464,0.015304834,1,-3.351377121,UP OGFOD1,0.972909827,5.841715972,2.47573188,0.015452011,1,-3.359612001,UP MYL12A,7.752194175,56.43498627,2.460190802,0.016085971,1,-3.394184143,UP TOMM5,0.760201173,5.377848882,2.445893805,0.016689657,1,-3.425825102,UP GOT2,5.636849772,35.36052042,2.437737088,0.017043082,1,-3.443806463,UP FAM103A1,0.782499849,4.569606008,2.418655679,0.017896137,1,-3.485670744,UP RBM8A,1.753819435,13.56334774,2.412026945,0.018201285,1,-3.500148219,UP PCBP2,6.17019764,53.95274636,2.406806122,0.018444881,1,-3.511526799,UP NUP93,0.826708281,5.921370794,2.374579675,0.020013923,1,-3.58129456,UP ARPC5,1.618670472,6.251016539,2.3582483,0.020853527,1,-3.61634181,UP CFAP20,1.179500161,8.571592225,2.349065227,0.021339252,1,-3.635957154,UP MAP1LC3B,3.510718182,17.48482131,2.335068053,0.022098936,1,-3.665728423,UP C1orf53,0.666428153,2.385947726,2.329486596,0.02240849,1,-3.677556993,UP FAM69C,3.715882035,10.23101857,2.325520535,0.022630781,1,-3.685947227,UP PRODH,0.587012356,0.752545164,2.302970001,0.023932205,1,-3.733417521,UP C2orf72,0.831057717,1.507031231,2.302026554,0.023988066,1,-3.73539479,UP DEGS1,4.330339491,22.05487243,2.282255916,0.025185485,1,-3.776667936,UP COG2,0.794491313,4.596642011,2.28150454,0.025232015,1,-3.778230398,UP NETO2,0.66486761,2.011833799,2.268601338,0.026042977,1,-3.804992271,UP PLD6,1.824314452,8.474601682,2.266562097,0.026173222,1,-3.809209651,UP RANBP10,1.933844613,9.608930777,2.265937251,0.026213246,1,-3.810501242,UP TMOD1,7.975726409,13.06748062,2.264925505,0.026278165,1,-3.812591915,UP GSE1,0.981423091,4.626439561,2.260906051,0.026537479,1,-3.820889677,UP PDK4,4.670177982,5.324956162,2.257307928,0.026771519,1,-3.828306735,UP CNN3,5.137689758,21.3213601,2.242094696,0.027781258,1,-3.859552726,UP CFDP1,2.352153731,13.93981605,2.221494159,0.029201834,1,-3.901568766,UP CIAPIN1,1.972459336,14.53519129,2.215466229,0.029629382,1,-3.913798802,UP PCBD1,4.67785959,40.71048323,2.199175515,0.030812409,1,-3.94670496,UP CBX5,1.360583307,7.969132073,2.192137204,0.031336186,1,-3.960855837,UP LRRN1,0.776446822,0.951359548,2.191853406,0.031357468,1,-3.961425591,UP TMEM26,1.838980763,2.316342512,2.178471543,0.032375425,1,-3.988217296,UP DNAJB1,4.127920277,28.38259702,2.160820034,0.03376223,1,-4.023335935,UP CHTOP,1.212784631,14.19257938,2.156481479,0.034110917,1,-4.031929109,UP DNAJC15,0.567916218,3.607949419,2.135651358,0.035829051,1,-4.072973637,UP FBXL14,0.645190163,3.821211022,2.134315885,0.035941727,1,-4.07559308,UP NGRN,0.987016465,5.710174986,2.125373702,0.036704158,1,-4.093095169,UP STMN1,3.762765193,16.41829239,2.119032863,0.037253266,1,-4.105466291,UP CDK15,0.625674178,0.803952777,2.118749456,0.037277974,1,-4.106018459,UP RND3,1.001843887,2.89810574,2.116547513,0.03747043,1,-4.110306321,UP TERF2IP,4.04132369,22.04240732,2.106089946,0.03839626,1,-4.130616367,UP FAM58A,1.673093802,11.49429781,2.104152292,0.038569964,1,-4.134369746,UP TUBB6,2.485809884,14.07535274,2.101504037,0.038808471,1,-4.139494644,UP L1CAM,10.5517714,11.02460527,2.091973815,0.03967738,1,-4.15789001,UP BCL7A,0.61484028,4.387421865,2.086920079,0.04014494,1,-4.167614608,UP RAN,6.653651385,50.22309287,2.084768068,0.04034548,1,-4.171749232,UP HOXC9,0.54090596,0.372081474,2.083122612,0.0404994,1,-4.174908057,UP HN1,1.460080819,8.559481201,2.07667293,0.041107619,1,-4.187268253,UP ALAD,1.47098251,10.43900695,2.070399232,0.041706793,1,-4.199258399,UP XG,1.392631498,4.061127455,2.069408378,0.041802111,1,-4.201149137,UP CRYAB,34.75696764,120.1432202,2.06332315,0.042391628,1,-4.212743196,UP HSPA1B,6.23680447,19.50429593,2.057243806,0.042987717,1,-4.224295597,UP TXNL4B,0.526828383,3.042446901,2.052072152,0.043500476,1,-4.234099163,UP ARSD,2.037291244,11.48073219,2.042560196,0.044457324,1,-4.252072737,UP TMEM117,1.635228201,8.066801008,2.04143634,0.044571565,1,-4.254191414,UP CACYBP,1.77017195,8.501754876,2.03890366,0.044829938,1,-4.258962157,UP GEMIN8,1.423987769,9.658330666,2.026663858,0.046096811,1,-4.28194319,UP CAPN2,2.991426535,15.72781251,2.023215232,0.046459261,1,-4.288395816,UP DEDD,0.878842071,10.75588573,2.020258889,0.046771916,1,-4.293919499,UP CAP2,1.153334783,4.030002105,2.016886526,0.04713077,1,-4.300211634,UP SEPHS1,1.309958319,10.82073148,2.010572858,0.047808956,1,-4.311966266,UP PWP1,2.813438929,20.62866333,2.009427882,0.047932836,1,-4.314094411,UP HSDL1,1.028400121,4.97102932,2.008502364,0.048033173,1,-4.315813856,UP FKBP4,6.310014506,38.59436573,2.005897633,0.04831652,1,-4.320649159,UP ZNF185,1.7023088,4.488535478,2.00441105,0.048478874,1,-4.323406255,UP TMEM106C,1.983523804,12.13196089,2.002870221,0.048647645,1,-4.32626202,UP HORMAD1,0.580752715,0.322494267,2.000729084,0.048883003,1,-4.330227117,UP JOSD1,1.262406781,13.97699164,2.000652765,0.048891411,1,-4.330368378,UP ATMIN,1.572489101,7.627694114,1.993084754,0.049731249,1,-4.344352268,UP ANXA2,12.42153207,67.16044217,1.99214382,0.049836524,1,-4.346087558,UP VMAC,-0.726679292,2.914348898,-3.794132042,0.000290082,1,0.186135401,DOWN NOXA1,-1.597714842,4.041858945,-2.996714244,0.003653215,1,-2.097331545,DOWN TMEM102,-1.110293778,3.709571894,-2.625241803,0.010406543,1,-3.017661647,DOWN NAALADL1,-0.89989959,1.575237607,-2.592846292,0.011351893,1,-3.09318055,DOWN SLC12A9,-0.953338446,5.96759959,-2.582788011,0.011660838,1,-3.116468626,DOWN CDKN2A,-1.246023447,3.055796107,-2.522730726,0.013668938,1,-3.253938072,DOWN RGS12,-3.945918316,21.00203916,-2.491114394,0.01484668,1,-3.325210655,DOWN TMEM200B,-1.607280116,2.515555267,-2.48007201,0.015279015,1,-3.349924072,DOWN HDAC10,-0.561160716,2.349168146,-2.436400382,0.017101635,1,-3.446748322,DOWN ACSS1,-1.093264827,4.992606335,-2.427344382,0.01750308,1,-3.466642737,DOWN TRIB3,-2.084438188,8.021769354,-2.419969196,0.017836215,1,-3.482797924,DOWN LRFN3,-1.193541677,6.383149574,-2.416250656,0.018006318,1,-3.49092736,DOWN PCED1A,-3.2502943,16.53205123,-2.363879699,0.020560544,1,-3.604280322,DOWN PRKD2,-1.307293365,8.385416585,-2.35774132,0.020880085,1,-3.617426459,DOWN PTK2B,-0.60613478,2.424832612,-2.347280043,0.021434834,1,-3.639762698,DOWN ARAF,-3.15847464,18.49771169,-2.312915213,0.02335031,1,-3.712531656,DOWN NT5C3B,-1.665961931,12.1146992,-2.300593778,0.024073121,1,-3.738396248,DOWN TMEM177,-0.691065103,5.118937536,-2.290142665,0.024701638,1,-3.760240682,DOWN FXYD6,-3.153104408,4.819935541,-2.267174771,0.026134031,1,-3.807942921,DOWN NUDT22,-1.329010951,7.645029177,-2.259483651,0.026629783,1,-3.823822999,DOWN CYB5R2,-0.733188522,3.361309542,-2.259065496,0.026656972,1,-3.824685028,DOWN TUBG2,-1.450355858,7.362245073,-2.230608735,0.028565633,1,-3.883020931,DOWN MAPK11,-1.188494719,6.87583096,-2.22915391,0.028666357,1,-3.885985909,DOWN ADAMTS2,-1.596356913,2.431271976,-2.218069458,0.029444073,1,-3.9085207,DOWN GHDC,-5.801209733,26.22278984,-2.207366219,0.030212533,1,-3.930186944,DOWN MROH6,-1.011288925,3.815773923,-2.188245804,0.031629105,1,-3.96866256,DOWN TMEM198,-1.139051913,6.085172686,-2.186180999,0.0317855,1,-3.972799904,DOWN PDE4A,-0.732281965,3.918993272,-2.180616617,0.032210332,1,-3.98393239,DOWN GRN,-44.30363863,182.3574065,-2.176981671,0.032490525,1,-3.991191213,DOWN COX6A2,-13.21032284,17.73490259,-2.167971216,0.033194271,1,-4.009138643,DOWN MGAT4B,-2.734333724,24.75732249,-2.157235377,0.034050103,1,-4.030436994,DOWN STK10,-3.730679189,16.91560136,-2.14902575,0.034717461,1,-4.046660672,DOWN ABHD12,-6.385622863,38.4343019,-2.14899687,0.034719829,1,-4.046717648,DOWN SH3TC1,-0.547552071,1.9204323,-2.141714893,0.035321313,1,-4.061062169,DOWN CYP27A1,-25.65997662,113.906269,-2.135398625,0.035850351,1,-4.073469468,DOWN PCDHGA10,-0.683590068,1.016279241,-2.135014789,0.035882721,1,-4.074222406,DOWN PLXNB2,-7.801212711,48.47116986,-2.130933123,0.036228515,1,-4.082221648,DOWN SNX17,-6.791015347,49.09796246,-2.126481209,0.036608974,1,-4.090931034,DOWN TMUB2,-1.540363877,14.0643884,-2.10919594,0.038119233,1,-4.124593424,DOWN MRM1,-1.615926029,9.08949665,-2.106538654,0.038356132,1,-4.129746749,DOWN HPN,-1.37411686,3.932086413,-2.082652658,0.040543453,1,-4.175809832,DOWN HPSE2,-0.943692653,1.115670779,-2.059780169,0.04273815,1,-4.219479521,DOWN C1RL,-1.05853074,2.877036984,-2.05837666,0.042876095,1,-4.222145175,DOWN ACSS2,-1.635724045,11.1629102,-2.050539177,0.043653476,1,-4.237000885,DOWN CHIT1,-3.349842326,2.661907472,-2.032656741,0.045472732,1,-4.270706648,DOWN ACVRL1,-0.960381368,3.231636997,-2.022915167,0.046490913,1,-4.288956792,DOWN TMEM101,-10.31831238,38.92966918,-2.018062805,0.047005335,1,-4.298018011,DOWN TM9SF4,-2.605018739,20.95756031,-2.010606892,0.047805278,1,-4.311902992,DOWN BLOC1S3,-1.210604107,8.43698059,-2.010022437,0.047868475,1,-4.31298946,DOWN HS3ST2,-1.164452196,2.116313833,-2.00363731,0.048563561,1,-4.324840548,DOWN MED22,-0.920105539,6.105288017,-1.990715591,0.049996682,1,-4.348720119,DOWN