uniprot_id,corset_id,cluster_id,annotation
PPAF2_IPOBA,Cluster-5787.0,7,Serine endopeptidase which; by cleaving prophenoloxidase activating factor PPAF2; is required for the activation of the prophenoloxidase cascade probably following the recognition of pathogen-derived products.
POLC2_TOBAC,Cluster-38783.0,4,NA
GRXC1_ORYSJ|GRXC3_ORYSJ,Cluster-42018.0,5,Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.|Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
AB19B_ARATH,Cluster-23418.0,5,Auxin efflux transporter that acts as a negative regulator of light signaling to promote hypocotyl elongation. Mediates the accumulation of chlorophyll and anthocyanin; as well as the expression of genes in response to light. Participates in auxin efflux and thus regulates the polar auxin basipetal transport (from auxin-producing leaves to auxin-sensitive tissues; and from root tips to root elongating zone). Involved in diverse auxin-mediated responses including gravitropism; phototropism and lateral root formation.
PP142_ARATH,Cluster-39637.0,5,NA
VINSY_RAUSE,Cluster-47119.0,4,Acetyltransferase that catalyzes the formation of vinorine; a precursor of the antiarrhythmic monoterpenoid indole alkaloid ajmaline. Acts on gardneral; but not on polyneuridine aldehyde or N-methylgardneral.
MYSP1_DROME,Cluster-1620.0,2,Paramyosin is a major structural component of many thick filaments isolated from invertebrate muscles.
DTX33_ARATH,Cluster-55790.0,1,NA
ASOL_TOBAC,Cluster-54043.0,4,Probable oxidoreductase that may be involved in pollen tube growth.
ASOL_TOBAC,Cluster-23541.0,4,Probable oxidoreductase that may be involved in pollen tube growth.
EF4L3_ARATH,Cluster-57257.0,1,Component of the central CCA1/LHY-TOC1 feedback loop in the circadian clock that promotes clock accuracy and is required for sustained rhythms in the absence of daily light/dark cycles.
FAFL_ARATH,Cluster-43632.0,4,Ubiquitin C-terminal hydrolase involved in development and the imd/NF-kappa-B (IMD) signaling cascade (PubMed:23919485; PubMed:1295747). Required for eye and embryo development; and plays a role in compound eye assembly and oogenesis respectively (PubMed:1295747). In the larval eye disks; cells outside the assembling facets require this protein for short-range cell interactions that prevent the mystery cells from becoming photoreceptors (PubMed:1295747). Also required for nuclear migration and cellularization in early embryogenesis and could play a role in pole cell determination; development or function (PubMed:1295747). Regulates the IMD signaling cascade at later stages of infection (around 6 hours post-infection) by inhibiting the expression of the antimicrobial peptides Dpt and Dro (PubMed:23919485). Acts by modulating the state of imd polyubiquitination and/or stability; a function which appears to be independent of its enzymatic activity (PubMed:23919485). In turn; imd enhances the polyubiquitination and stability of faf suggesting that they may form a regulatory feedback mechanism within the Imd pathway (PubMed:23919485).
AAE_RAUSE|GDL74_ARATH,Cluster-34056.0,2,Deacetylates 17-O-acetylajmaline and 17-O-acetylnorajmaline; but is inactive toward other acetylated alkaloids.|
RH20_ORYSJ,Cluster-44984.0,5,ATP-dependent RNA helicase involved nonsense-mediated mRNA decay and ribosome biogenesis through rRNA processing.
CYSK1_BRAJU|CYSK_SOLTU,Cluster-3606.0,2,Catalyzes the formation of cysteine and acetate from O-acetylserine and hydrogen sulfide (PubMed:24100226; PubMed:22405203). By metabolizing hydrogen sulfide produced by cysl-2-mediated cyanide assimilation; mediates resistance to P.aeruginosa infection (PubMed:21840852). Mediates survival in high levels of hydrogen sulfide (PubMed:22405203). By sequestering egl-9; which in turn promotes hif-1-mediated transcription; regulates behavioral responses to hypoxia (PubMed:22405203).|May be the GTPase; regulating ATP sulfurylase activity.
WRK35_ARATH|WRK14_ARATH,Cluster-24620.0,5,Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'); a frequently occurring elicitor-responsive cis-acting element.|Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'); a frequently occurring elicitor-responsive cis-acting element.
FAH2_ARATH|FAH1_ARATH,Cluster-32499.0,4,Fatty acid 2-hydroxylase involved in the alpha-hydroxylation of the long-chain fatty acid (LCFA) palmitic acid. Probably involved in the resistance response to oxidative stress.|Fatty acid 2-hydroxylase involved in the alpha-hydroxylation of sphingolipid-associated very long-chain fatty acids (VLCFA). Probably involved in the resistance response to oxidative stress.
AG_SOLLC,Cluster-43693.0,5,Probable transcription factor involved in regulating genes that determines stamen and carpel development in wild-type flowers.
NPY1_ARATH,Cluster-46509.0,2,May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Coregulates with PID the auxin-mediated plant organogenesis. Regulates cotyledon development through control of PIN1 polarity. May play an essential role in root gravitropic responses.
CALS5_ARATH,Cluster-17076.1,4,Required for the formation of the callose wall separating the tetraspores (interstitial wall) and surrounding the pollen mother cells (pheripheral wall). Required for exine formation on pollen wall. May be involved in callose synthesis during pollen tube growth. During plant growth and development; callose is found as a transitory component of the cell plate in dividing cells; is a major component of pollen mother cell walls and pollen tubes; and is found as a structural component of plasmodesmatal canals.
CALS5_ARATH,Cluster-43397.0,4,Required for the formation of the callose wall separating the tetraspores (interstitial wall) and surrounding the pollen mother cells (pheripheral wall). Required for exine formation on pollen wall. May be involved in callose synthesis during pollen tube growth. During plant growth and development; callose is found as a transitory component of the cell plate in dividing cells; is a major component of pollen mother cell walls and pollen tubes; and is found as a structural component of plasmodesmatal canals.
IAMT1_ARATH,Cluster-25630.0,5,Catalyzes the methylation of the free carboxyl end of the plant hormone indole-3-acetic acid (IAA). Converts IAA to IAA methyl ester (MeIAA). Regulates IAA activities by IAA methylation. Methylation of IAA plays an important role in regulating plant development and auxin homeostasis. Required for correct leaf pattern formation. MeIAA seems to be an inactive form of IAA.
MDIS2_ARATH,Cluster-48688.0,4,Involved in the pollen tube perception of the female signal by binding an unidentified female attractant (PubMed:26863186). May be involved in the regulation of root hairs development (PubMed:16367956).
ASMT_ARATH|COMT1_MEDSA,Cluster-534.4,2,Methyltransferase which catalyzes the transfer of a methyl group onto N-acetylserotonin; producing melatonin (N-acetyl-5-methoxytryptamine). Does not seem to possess caffeate O-methyltransferase activity.|Catalyzes the conversion of caffeic acid to ferulic acid and of 5-hydroxyferulic acid to sinapic acid. The resulting products may subsequently be converted to the corresponding alcohols that are incorporated into lignins.
ATAD1_RAT,Cluster-35333.0,4,ATPase that plays a critical role in regulating the surface expression of AMPA receptors (AMPAR); thereby regulating synaptic plasticity and learning and memory. Required for NMDA-stimulated AMPAR internalization and inhibition of GRIA1 and GRIA2 recycling back to the plasma membrane; these activities are ATPase-dependent.
RPM1_ARATH,Cluster-29959.0,5,NA
PTR53_ARATH|PTR8_ARATH,Cluster-50499.0,5,|Low-affinity nitrate transporter facilitating nitrate loading into root phloem. Not involved in dipeptides transport; but has a weak glucosinolate transport activity.
CWPX_ARATH,Cluster-56265.1,4,NA
PPR6_ARATH,Cluster-31365.0,5,NA
AX10A_SOYBN,Cluster-56647.0,4,Catalyzes the hydrolysis of sphingomyelin. May also act on other phosphatidyl esters. Induces complement-dependent hemolysis and dermonecrosis.
CNGC4_ARATH,Cluster-55291.1,5,Acts as cyclic nucleotide-gated ion channel. Permeable to potassium and sodium in a cyclic nucleotide-dependent fashion (cAMP or cGMP). Might constitute a common downstream component of the signaling pathways leading to hypersensitive response (HR).
DRM1_ARATH,Cluster-46590.0,4,Involved in de novo DNA methylation. Controls asymmetric and CpNpG methylation. Required for FWA gene silencing but not for the maintenance of SUP gene silencing. Functionally redundant to CMT3 to maintain non-CpG methylation. Involved in RNA-directed DNA methylation (RdDM) (PubMed:12121623; PubMed:12151602; PubMed:14680640). Acts as major DNA methyltransferase in the RdDM pathway; and is essential for RNA-directed de novo DNA methylation of cytosines in all sequence contexts (PubMed:21060858; PubMed:21212233). Associates with long non-coding RNA (lncRNA) produced by RNA polymerase V (Pol V). This association is dependent on AGO4 and IDN2; and results in DNA methylation of RdDM target loci (PubMed:24862207).
SPSA1_CITUN,Cluster-25475.0,4,Plays a role in photosynthetic sucrose synthesis by catalyzing the rate-limiting step of sucrose biosynthesis from UDP-glucose and fructose- 6-phosphate. Involved in the regulation of carbon partitioning in the leaves of plants. May regulate the synthesis of sucrose and therefore play a major role as a limiting factor in the export of photoassimilates out of the leaf. Plays a role for sucrose availability that is essential for plant growth and fiber elongation.
VESTR_MEDSA,Cluster-54919.0,4,Stereospecific enzyme that catalyzes the NADPH-dependent reduction of (3R)-vestitone to (3R;4R)-4'-methoxyisoflavan-2';4;7-triol (DMI). Has no activity with (3S)-vestitone. Catalyzes the penultimate step in the biosynthesis of the phytoalexin medicarpin; and thereby contributes to plant defense reactions.
Y2913_ARATH,Cluster-37414.0,3,NA
LOG1_ARATH|LOG4_ARATH,Cluster-52292.0,2,Cytokinin-activating enzyme working in the direct activation pathway. Phosphoribohydrolase that converts inactive cytokinin nucleotides to the biologically active free-base forms.|Cytokinin-activating enzyme working in the direct activation pathway. Phosphoribohydrolase that converts inactive cytokinin nucleotides to the biologically active free-base forms.
LOGL6_ORYSJ,Cluster-10394.0,2,Cytokinin-activating enzyme working in the direct activation pathway. Phosphoribohydrolase that converts inactive cytokinin nucleotides to the biologically active free-base forms.
BRX_ARATH|BRXL1_ARATH,Cluster-30917.0,2,|May act as a regulator of cell proliferation and elongation in the root.
DTX30_ARATH,Cluster-28594.0,5,Positively mediates root hair elongation.
LOB_ARATH,Cluster-42729.0,5,Not known; ectopic expression of LOB leads to alterations in the size and shape of leaves and floral organs and causes male and female sterility.
AAP3_ARATH,Cluster-41296.0,2,NA
HSL1_ARATH,Cluster-48761.0,3,NA
CDPKB_ARATH,Cluster-55430.0,4,May play a role in signal transduction pathways that involve calcium as a second messenger. Functions as regulator of the calcium-mediated abscisic acid (ABA) signaling pathway. Phosphorylates ABA-responsive transcription factors ABF1 and ABF4 in vitro.
ARAK_ARATH,Cluster-42570.0,1,Arabinose kinase. Involved in the salvage pathway which converts free L-arabinose to UDP-L-arabinose. May play a role in arabinose transport.
TMN7_ARATH,Cluster-56650.0,5,NA
SALAT_PAPSO,Cluster-11218.0,2,Involved in biosynthesis of morphinan-type benzylisoquinoline alkaloids. Catalyzes the conversion of the phenanthrene alkaloid salutaridinol to salutaridinol-7-O-acetate; the immediate precursor of thebaine along the morphine biosynthetic pathway. Conversion of 7-O-acetylsalutaridinol into thebaine is spontaneous.
PSAN_ARATH,Cluster-50906.0,3,NA
AFP3_ARATH,Cluster-47630.0,4,Acts as a negative regulator of abscisic acid (ABA) response and stress responses.
RPT3_ARATH,Cluster-485.1,7,May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Signal transducer of the phototropic response and photo-induced movements. Involved in the phot1 pathway under low blue light (LBL) fluence rate and in the phot2 pathway under higher fluence rate of blue light (HBL). Necessary for root and hypocotyl phototropisms; but not for the regulation of stomata opening. Not involved in chloroplast accumulation and translocation.
PER55_ARATH|PER51_ARATH,Cluster-35363.0,2,Removal of H(2)O(2); oxidation of toxic reductants; biosynthesis and degradation of lignin; suberization; auxin catabolism; response to environmental stresses such as wounding; pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.|Removal of H(2)O(2); oxidation of toxic reductants; biosynthesis and degradation of lignin; suberization; auxin catabolism; response to environmental stresses such as wounding; pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.
AL2C4_ARATH,Cluster-26809.0,3,Involved in ferulic acid and sinapic acid biosynthesis by oxidation of conyferylaldehyde and sinapaldehyde; respectively. Can oxidize L-lactaldehyde. Possesses activity on acetaldehyde and glycolaldehyde in vitro.
KCS6_ARATH,Cluster-41192.0,5,Contributes to cuticular wax and suberin biosynthesis. Involved in both decarbonylation and acyl-reduction wax synthesis pathways. Required for elongation of C24 fatty acids; an essential step of the cuticular wax production (PubMed:10330468; PubMed:11041893). Major condensing enzyme for stem wax and pollen coat lipid biosynthesis (PubMed:12467640).
GH311_ORYSJ|GH39_ARATH,Cluster-49589.0,5,May catalyze the synthesis of indole-3-acetic acid (IAA)-amino acid conjugates; providing a mechanism for the plant to cope with the presence of excess auxin.|Catalyzes the synthesis of indole-3-acetic acid (IAA)-amino acid conjugates; providing a mechanism for the plant to cope with the presence of excess auxin.
EXPA1_ORYSJ|EXP11_ARATH,Cluster-55973.0,4,May cause loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found. May be required for rapid internodal elongation in deepwater rice during submergence.|Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found.
STP13_ARATH,Cluster-46843.0,6,Mediates an active uptake of hexoses; probably by sugar/hydrogen symport.
MST4_ORYSJ|STP13_ARATH,Cluster-41385.0,1,|Mediates an active uptake of hexoses; probably by sugar/hydrogen symport.
AMO_ARATH,Cluster-27569.1,5,Involved in the biosynthesis of artemisin. Catalyzes three consecutive oxidations of amorpha-4;11-diene to produce artemisinic acid; but is unable to oxidize germacrene A. No activity with limonene; alpha-pinene; beta-pinene; pinocarveol; (-)-alloisolongifolene; caryophyllene; (-)-alpha-gurjunene; (+)-gamma-gurjunene; (+)-ledene; (+)-beta-selinene and (+)-valencene as substrates.
AMO_ARATH,Cluster-27569.0,5,Involved in the biosynthesis of artemisin. Catalyzes three consecutive oxidations of amorpha-4;11-diene to produce artemisinic acid; but is unable to oxidize germacrene A. No activity with limonene; alpha-pinene; beta-pinene; pinocarveol; (-)-alloisolongifolene; caryophyllene; (-)-alpha-gurjunene; (+)-gamma-gurjunene; (+)-ledene; (+)-beta-selinene and (+)-valencene as substrates.
ZIP1_ARATH,Cluster-16228.0,5,Mediates zinc uptake from the rhizosphere. May also transport copper and cadmium ions.
BBX21_ARATH,Cluster-41962.0,1,Transcription activator that acts as positive regulator of seedling photomorphogenesis (PubMed:17965270). Acts downstream of COP1 and play an important role in early and long-term adjustment of the shade avoidance syndrome (SAS) responses in natural environments (PubMed:21070414).
SMR6_ARATH,Cluster-52262.0,4,Probable cyclin-dependent protein kinase (CDK) inhibitor that functions as a repressor of mitosis in the endoreduplication cell cycle (By similarity). May inhibit CDKA-1/CYCD complexes during S-phase; preventing the re-initiation of DNA replication (PubMed:20706207).
SRG1_ARATH,Cluster-49794.1,5,NA
PXG5_ARATH,Cluster-53037.1,4,Calcium-binding peroxygenase involved in the degradation of storage lipid in oil bodies. May be involved in the interaction between oil bodies and vacuoles during seed germination.
NLP2_ARATH|NLP3_ARATH,Cluster-26289.0,4,Probable transcription factor.|
REXO4_YEAST|REXO4_GIBZE,Cluster-40955.0,2,Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1; the internal transcribed spacer localized between the 18S and 5.8S rRNAs.|
RIC1_ARATH|RIC7_ARATH,Cluster-46111.0,4,Functions as downstream effector of Rho-related GTP binding proteins of the Rho of Plants" (ROPs) family. Participates in the propagation of ROP GTPase signals in specific cellular responses. Required for cortical microtubule organization. Promotes microtubule bundling and formation of well-ordered microtubule arrays in the neck region of pavement cells. This restricts cell lateral expansion to generate the narrow neck morphology of pavement cells. Its function is inhibited when it interacts with activated ARAC4/ROP2. Represses ARAC4/ROP2 activation and antagonizes the RIC4-actin pathway that promotes the assembly of cortical actin microfilaments. Acts as downstream effector of ARAC3/ROP6 which functions in a signaling pathway that negatively regulates clathrin-mediated endocytosis and internalization of PIN1 and PIN2. Required for the asymmetric auxin distribution during root gravitropism and vascular patterning. Positively regulates auxin responses; but negatively regulates ABA responses during lateral root development and primary root elongation.|Functions as downstream effector of Rho-related GTP binding proteins of the "Rho of Plants" (ROPs) family. Participates in the propagation of ROP GTPase signals in specific cellular responses. Functions as downstream effector of active ARAC4/ROP2 GTPase which is involved in the prevention of excessive stomatal opening upon light stimulation. Is involved in pollen tube growth regulation through its interaction with ARAC11/ROP1."
Y1669_ARATH,Cluster-56819.0,1,NA
RIE1_ARATH,Cluster-48006.0,2,NA
PITC_DICDI,Cluster-40390.0,6,Has phosphatidylinositol transfer activity.
GDL15_ARATH,Cluster-35579.0,4,Involved in the control of the PYK10 complex size and possibly substrate specificity. May be exported from the endoplamic reticulum upon interaction with MVP1.
COX1_HUMAN|NDUS6_PANTR,Cluster-25364.1,3,Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.|Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I); that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
EJ2_SOLLC|AGL70_ARATH,Cluster-27128.1,4,MADS-box transcription factor that acts redundantly with J2 to control meristem maturation and inflorescence architecture.|Probable transcription factor involved in the negative regulation of flowering time; probably through the photoperiodic and vernalization pathways; more efficient in cv. Landsberg erecta than in cv. Columbia background. Prevents premature flowering (PubMed:12724541; PubMed:25339407). Involved in the modulation of vernalization impact on flowering according to genotype acclimation to altitude (PubMed:25339407).
NAT1_ARATH,Cluster-2035.2,2,Non-catalytic component of the NatA N-terminal acetyltransferase; which catalyzes acetylation of proteins beginning with Met-Ser; Met-Gly and Met-Ala. N-acetylation plays a role in normal eukaryotic translation and processing; protect against proteolytic degradation and protein turnover. nat1 anchors ard1 and nat5 to the ribosome and may present the N termini of nascent polypeptides for acetylation.
NUDT1_ARATH|NUDT1_ROSHC,Cluster-35987.0,1,Mediates the hydrolysis of some nucleoside diphosphate derivatives. Its substrate specificity is unclear. In vitro; it can use NTP; dNTP; 8-oxo-GTP; 8-oxo-dGTP; dGTP; dATP; dTTP or dihydroneopterin triphosphate (DHNTP) as substrate. Has some NADH pyrophosphatase activity in vitro; however; such activity may not be relevant in vivo due to the high concentration of manganese used during the experiments. Plays an important role in protection against oxidative DNA and RNA damage by removing oxidatively damaged form of guanine.|Involved in a cytosolic pathway for the biosynthesis of free monoterpene alcohols that contribute to fragrance. Lacks terpene synthase activity; but has a diphosphohydrolase activity with geranyl diphosphate and farnesyl diphosphate as substrates. No activity with 8-oxo-dGTP and dGTP and unable to dephosphorylate geranyl phosphate to geraniol.
SAU23_ARATH,Cluster-46792.0,4,Functions as positive effectors of cell expansion through modulation of auxin transport.
PER1_SORBI,Cluster-44519.0,4,Removal of H(2)O(2); oxidation of toxic reductants; biosynthesis and degradation of lignin; suberization; auxin catabolism; response to environmental stresses such as wounding; pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue. Has a high preference for hydroxycinnamates as substrates. Substrate preference is ferulic acid > p-coumaric acid > N-acetyl tyrosine methyl ester > N-acetyl-tyrosine > tyrosine > catechol > Gly-Tyr-Gly. May be involved in the formation of diferulate linkages in the plant cell wall.
PUMP4_ARATH|TIP11_ARATH,Cluster-31849.21,1,PUMPS are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane; thus uncoupling oxidative phosphorylation. This leads to a decrease in the efficiency of oxidative phosphorylation and an increase in heat production. May be involved in protecting plant cells against oxidative stress damage (By similarity). Recombinant PUMP4; reconstituted into liposomes; transports a wide range of dicarboxylic acids including malate; oxaloacetate and succinate as well as phosphate; sulfate and thiosulfate. However; it is unknown if these transports are of any biological significance in vivo.|Water channel required to facilitate the transport of water; diffusion of amino acids and/or peptides from the vacuolar compartment to the cytoplasm. Does not promote glycerol permeability. May play a role in the control of cell turgor and cell expansion. Its function is impaired by Hg(2+). May be involved in a vesicle-based metabolite routing through or between pre-vacuolar compartments and the central vacuole. Transports urea in yeast cells in a pH-independent manner. Transports H(2)O(2) in yeast cells.
AVP1_ARATH,Cluster-41917.1,7,Contributes to the transtonoplast (from cytosol to vacuole lumen) H(+)-electrochemical potential difference. It establishes a proton gradient of similar and often greater magnitude than the H(+)-ATPase on the same membrane. In addition; facilitates auxin transport by modulating apoplastic pH and regulates auxin-mediated developmental processes. Confers tolerance to NaCl and to drought by increasing ion retention.
STP10_ARATH,Cluster-55609.1,4,NA
STP10_ARATH,Cluster-55609.0,4,NA
PLT5_ARATH,Cluster-53431.1,4,Plasma membrane broad-spectrum sugar-proton symporter. Mediates the uptake of linear polyols such as sorbitol; xylitol; erythritol or glycerol. Can transport the cyclic polyol myo-inositol and different hexoses; pentoses (including ribose); tetroses and sugar alcohols.
WRKY4_ARATH|WRK58_ARATH,Cluster-46892.0,1,Transcription factor that binds specifically to the W box (5'-(T)TGAC[CT]-3'); a frequently occurring elicitor-responsive cis-acting element. Has a positive role in resistance to necrotrophic pathogens (e.g. Botrytis cinerea); but a negative effect on plant resistance to biotrophic pathogens (e.g. Pseudomonas syringae).|Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'); a frequently occurring elicitor-responsive cis-acting element.
A70_ARATH,Cluster-36802.0,7,Catalyzes the hydrolysis of sphingomyelin. May also act on other phosphatidyl esters. Induces complement-dependent hemolysis; dermonecrosis; blood vessel permeability and platelet aggregation.
FBD15_ARATH,Cluster-13656.1,6,NA
RCA1_LARTR|RCA2_LARTR,Cluster-55288.0,2,Activation of RuBisCO (ribulose-1;5-bisphosphate carboxylase/oxygenase; EC 4.1.1.39) involves the ATP-dependent carboxylation of the epsilon-amino group of lysine leading to a carbamate structure.|Activation of RuBisCO (ribulose-1;5-bisphosphate carboxylase/oxygenase; EC 4.1.1.39) involves the ATP-dependent carboxylation of the epsilon-amino group of lysine leading to a carbamate structure.
ADF11_ORYSJ,Cluster-50082.2,4,Actin-depolymerizing protein. Severs actin filaments (F-actin) and binds to actin monomers.
P2C52_ARATH,Cluster-52034.0,4,Protein phosphatase that acts as negative regulator of abscisic acid (ABA) signaling. Involved in the regulation of root architecture development and drought resistance. Can dephosphorylate SAPK8 and SAPK10 in vitro. Together with PYL10; SAPK8 and SAPK10; may form an ABA signaling module involved in stress response.
KCS4_ARATH,Cluster-2367.0,2,NA
XTH33_ARATH|DDPS6_ARATH,Cluster-44410.0,4,Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers; an essential constituent of the primary cell wall; and thereby participates in cell wall construction of growing tissues.|Catalyzes cis-prenyl chain elongation to produce the polyprenyl backbone of dolichol; a glycosyl carrier-lipid required for the biosynthesis of several classes of glycoprotein.
RBS8_NICPL|RBS3B_ARATH,Cluster-22139.0,2,RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1;5-bisphosphate; the primary event in carbon dioxide fixation; as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.|RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1;5-bisphosphate; the primary event in carbon dioxide fixation; as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.
INV1_DAUCA,Cluster-50614.0,4,NA
PME43_ARATH,Cluster-57052.0,4,Acts in the modification of cell walls via demethylesterification of cell wall pectin.
MAA3_ARATH,Cluster-51311.0,4,NA
DEAHC_ARATH,Cluster-32970.0,5,NA
KNAT2_ARATH|KNAT1_ARATH,Cluster-40815.0,5,May play a role in meristem function; and may be involved in maintaining cells in an undifferentiated; meristematic state. Probably binds to the DNA sequence 5'-TGAC-3'.|
IDD15_ARATH|IDD14_ARATH,Cluster-54469.0,3,Transcription factor involved in inflorescence stems gravitropism; probably by regulating starch accumulation in amyloplasts of graviperceptive cells. Required for stem circumnutation movements. Regulates lateral organ morphogenesis and gravitropic responses (PubMed:24039602). Acts cooperatively with IDD16 to control silique and branche orientation (PubMed:24039602). Involved in the establishment of auxin gradients through the regulation of auxin biosynthesis and transport (PubMed:24039602).|Transcription factor regulating starch metabolism by binding directly to the promoter of QQS (PubMed:21556057). The IDD14beta isoform attenuates the transcription factor activity by competitively forming heterodimers with reduced DNA-binding capacity(PubMed:21556057). Regulates lateral organ morphogenesis and gravitropic responses (PubMed:24039602). Has a redundant role with IDD16 in directing leaf and floral organ morphogenesis (PubMed:24039602). Involved in the establishment of auxin gradients through the regulation of auxin biosynthesis and transport (PubMed:24039602).
MMD1_ARATH,Cluster-27041.0,5,NA
MOB1A_MEDSF,Cluster-15336.0,1,Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1; in complex with its regulatory protein SAV1; phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1; which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation; cell death; and cell migration. Stimulates the kinase activity of STK38 and STK38L. Acts cooperatively with STK3/MST2 to activate STK38.
BSP_BOSSE,Cluster-45067.0,5,Metalloprotease; digests gelatin and azocasein (in vitro).
PMA9_ARATH,Cluster-39840.0,4,The plasma membrane H(+) ATPase of plants and fungi generates a proton gradient that drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.
PBL3_ARATH,Cluster-28273.0,6,May be involved in plant defense signaling.
U83A1_ARATH,Cluster-50893.0,4,NA
ZDH21_ARATH,Cluster-40750.0,4,Palmitoyl acyltransferase.
U73D1_ARATH,Cluster-40108.0,3,NA
BH025_ARATH,Cluster-42560.0,5,NA
BLH4_ARATH|BLH3_ARATH,Cluster-49805.0,2,Transcription factor that establishes leaf shape by repressing growth in specific subdomains of the leaf. Negatively regulates knox homeobox gene KNAT1/BP expression.|Transcription factor that is responsive of the nuclear import of SHOOT MERISTEMLESS (STM).
RPT2_ARATH,Cluster-36106.0,1,May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Signal transducer of the phototropic response and photo-induced movements. Necessary for root phototropism. Involved in hypocotyl phototropism under high rate but not under low rate light. Regulates stomata opening. Seems to be not involved in chloroplast accumulation and translocation.
RPT2_ARATH,Cluster-54984.0,4,May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Signal transducer of the phototropic response and photo-induced movements. Necessary for root phototropism. Involved in hypocotyl phototropism under high rate but not under low rate light. Regulates stomata opening. Seems to be not involved in chloroplast accumulation and translocation.
RIN4_ARATH,Cluster-37749.0,7,Essential regulator of plant defense; which plays a central role in resistance in case of infection by a pathogen. It is a common target for both type III avirulence proteins from P.syringae (AvrB; AvrRpm1 and AvrRpt2) and for the plant Resistance (R) proteins RPM1 and RPS2. In strains carrying the appropriate R gene for avirulence proteins of the pathogen; its association with avirulence proteins triggers a defense system including the hypersensitive response; which limits the spread of disease. In contrast; in plants lacking appropriate R genes; its association with avirulence proteins of the pathogen impairs the defense system and leads to the pathogen multiplication.
PME53_ARATH,Cluster-48545.0,5,Acts in the modification of cell walls via demethylesterification of cell wall pectin.
NLTP6_AMBAR,Cluster-57679.1,5,Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
SAU72_ARATH,Cluster-43657.0,3,Plays a role in the regulation of cell expansion; root meristem patterning and auxin transport.
CCD32_ARATH|CCD33_ARATH,Cluster-22719.2,2,|
AB13B_ARATH,Cluster-30768.0,1,NA
GRF1_ARATH,Cluster-44775.0,2,Transcription activator that plays a role in the regulation of cell expansion in leaf and cotyledons tissues. Component of a network formed by miR396; the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function; at least partially through the control of cell proliferation. microRNA396-GRF1/GRF3 regulatory module acts as a developmental regulator in the reprogramming of root cells during cyst nematode infection; leading to the formation of the syncytium.
CHSY_ANTMA,Cluster-6599.8,2,The primary product of this enzyme is 4;2';4';6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
PME28_ARATH,Cluster-44845.0,4,Acts in the modification of cell walls via demethylesterification of cell wall pectin.
RNHX1_ARATH,Cluster-12689.1,6,Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
PLY56_SOLLC|PLY59_SOLLC,Cluster-40296.0,4,|Might be needed during pollen development and tube growth.
MY106_ARATH|MYB16_ARATH,Cluster-21713.0,2,Functions as a repressor of epidermal cell outgrowth and negatively regulate trichome branch formation (PubMed:18805951; PubMed:21070410). Acts as both a positive and negative regulator of cellular outgrowth. Promotes both trichome expansion and branch formation (PubMed:21070410). Coordinately with WIN1/SHN1; participates in the regulation of cuticle biosynthesis and wax accumulation in reproductive organs and trichomes. Functions in cuticle nanoridge formation in petals and stamens; and in morphogenesis of petal conical cells and trichomes (PubMed:23709630). May play a role in the regulation of cuticle formation in vegetative organs (PubMed:24169067).|Involved in the control of epidermal cell morphogenesis in petals. Promotes unidirectional cell expansion once outgrowth has been initiated (PubMed:17376813). Coordinately with WIN1/SHN1; participates in the regulation of cuticle biosynthesis and wax accumulation in reproductive organs and trichomes. Functions in cuticle nanoridge formation in petals and stamens; and in morphogenesis of petal conical cells and trichomes (PubMed:23709630). Functions as a major regulator of cuticle formation in vegetative organs by regulating the cuticle biosynthesis genes CYP86A8/LCR and CER1 (PubMed:24169067).
HSF2_CHICK|HSFA9_ARATH,Cluster-44277.0,6,DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. HSF2 shows constitutive DNA binding activity; even without heat shock.|Seed-specific transcriptional regulator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE). Seems to be specialized for the developmental expression of heat shock protein (HSP) genes during seed maturation. Activated by ABI3.
P2C14_ARATH,Cluster-19489.0,2,Key component and repressor of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses; such as stomatal closure; seed germination and inhibition of vegetative growth. Confers enhanced sensitivity to drought.
KAT1_ARATH|KAT2_ARATH,Cluster-9088.1,7,Highly selective inward-rectifying potassium channel. This voltage-gated channel could mediate long-term potassium influx into guard cells leading to stomatal opening. Assuming opened or closed conformations in response to the voltage difference across the membrane; the channel is activated by hyperpolarization. The channel activity is enhanced upon external acidification. Also permeable to ammonium ions. Blocked by tetraethylammonium and barium ions.|Highly selective inward-rectifying potassium channel. This voltage-dependent channel could mediate long-term potassium influx into guard cells leading to stomatal opening. Assuming opened or closed conformations in response to the voltage difference across the membrane; the channel is activated by hyperpolarization. The channel activity is enhanced upon external acidification.
CCD51_ORYSJ,Cluster-30892.0,2,NA
Y1130_ARATH|Y1133_ARATH,Cluster-15561.0,7,|
GIL1_ARATH,Cluster-55645.1,1,Required for red (R) and far red (FR) light-induced and phytochrome-mediated deregulation of negative gravitropism leading to randomization of hypocotyl growth orientation.
GIL1_ARATH,Cluster-55645.0,1,Required for red (R) and far red (FR) light-induced and phytochrome-mediated deregulation of negative gravitropism leading to randomization of hypocotyl growth orientation.
STEP1_ARATH,Cluster-38109.0,2,NA
GLR36_ARATH,Cluster-31147.0,1,Glutamate-gated receptor that probably acts as non-selective cation channel. Mediates leaf-to-leaf wound signaling. May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells.
GLR36_ARATH|GLR33_ARATH,Cluster-24906.0,1,Glutamate-gated receptor that probably acts as non-selective cation channel. Mediates leaf-to-leaf wound signaling. May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells.|Glutamate-gated receptor that probably acts as non-selective cation channel; at least in roots and hypocotyls. Can be triggered by Ala; Asn; Cys; Glu; Gly; Ser and glutathione (a tripeptide consisting of Glu-Gly-Cys). Mediates leaf-to-leaf wound signaling. May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells.
RUBR_PYRFU,Cluster-48303.0,1,Rubredoxin is a small nonheme; iron protein lacking acid-labile sulfide. Its single Fe; chelated to 4 Cys; functions as an electron acceptor and may also stabilize the conformation of the molecule.
RUBR_PYRFU,Cluster-48303.1,2,Rubredoxin is a small nonheme; iron protein lacking acid-labile sulfide. Its single Fe; chelated to 4 Cys; functions as an electron acceptor and may also stabilize the conformation of the molecule.
EPHA_MYCTU|HYES_HUMAN,Cluster-45272.0,2,Could be involved in detoxification of extraneous host-cell epoxides. Catalyzes the hydrolysis of epoxide-containing substrates.|Bifunctional enzyme (PubMed:12574510). The C-terminal domain has epoxide hydrolase activity and acts on epoxides (alkene oxides; oxiranes) and arene oxides (PubMed:12869654; PubMed:12574510; PubMed:22798687). Plays a role in xenobiotic metabolism by degrading potentially toxic epoxides (By similarity). Also determines steady-state levels of physiological mediators (PubMed:12869654; PubMed:12574510; PubMed:22798687). The N-terminal domain has lipid phosphatase activity; with the highest activity towards threo-9;10-phosphonooxy-hydroxy-octadecanoic acid; followed by erythro-9;10-phosphonooxy-hydroxy-octadecanoic acid; 12-phosphonooxy-octadec-9Z-enoic acid and 12-phosphonooxy-octadec-9E-enoic acid (PubMed:12574510).
HQGT_RAUSE,Cluster-55152.0,4,Broad spectrum multifunctional glucosyltransferase. In addition to hydroquinone it accept at least 45 natural and synthetic phenols as well as two cinnamyl alcohols as substrates. Hydroquinone was however the best substrate. In contrast to this broad acceptor substrate specificity; only pyrimidine nucleotide activated glucose is tolerated as a donor substrate.
ACT11_SOLTU,Cluster-35132.0,4,Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming; cell shape determination; cell division; organelle movement and extension growth.
COMT1_CATRO|COMT1_POPTM,Cluster-52592.0,4,Catalyzes the conversion of caffeic acid to ferulic acid and of 5-hydroxyferulic acid to sinapic acid. The resulting products may subsequently be converted to the corresponding alcohols that are incorporated into lignins.|
FB119_ARATH,Cluster-50292.0,3,NA
Y1465_ARATH,Cluster-25369.0,5,NA
CSE_ARATH,Cluster-37521.0,5,Esterase involved in the biosynthesis of lignin. Hydrolyzes caffeoylshikimate into caffeate and shikimate. Together with 4-coumarate--CoA ligase (4CL); acts on an alternative reaction for the formation of caffeoyl-CoA and bypasses the second reaction of shikimate O-hydroxycinnamoyltransferase (HST). Accepts also 4-coumaroylshikimate as substrate; but with lower activity. According to PubMed:20345607 and PubMed:22915575; posseses monoacylglycerol O-acyltransferase; monoacylglycerol lipase and lysophospholipase activities in vitro. With the association of ACBP2; may promote the degradation of lysophosphatidylcholine and detoxify the peroxidized membrane in response to cadmium-induced oxidative stress. However these results require additional confirmation in vivo.
SLAH3_ARATH,Cluster-52749.0,5,Slow; weak voltage-dependent S-type anion efflux channel involved in maintenance of anion homeostasis (PubMed:18305482). Binds to the highly selective inward-rectifying potassium channel KAT1 and inhibits its activity. Functions as an essential negative regulator of inward potassium channels in guard cells. Essential for the efficient stomatal closure and opening in guard cells (PubMed:27002025).
CY12_SOLTU,Cluster-31926.0,3,This is the heme-containing component of the cytochrome b-c1 complex; which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain.
HOX27_ORYSI|HAT22_ARATH,Cluster-48228.0,2,Probable transcription factor.|Probable transcription factor.
GDL57_ARATH,Cluster-41778.0,5,NA
DRL4_ARATH,Cluster-52993.1,5,Potential disease resistance protein.
GAOX2_ARATH,Cluster-55069.0,4,Key oxidase enzyme in the biosynthesis of gibberellin that catalyzes the conversion of GA12 and GA53 to GA9 and GA20 respectively; via a three-step oxidation at C-20 of the GA skeleton. GA53 is less effectively oxidized than GA12; and GA25 is also formed as a minor product. Involved in the promotion of the floral transition; fertility and silique elongation; but plays only a minor role in elongation of seedling organs. Acts redundantly with GA20OX1.
NLTL5_ARATH,Cluster-36357.0,7,NA
Y5625_ARATH,Cluster-29506.0,5,NA
NAC31_ARATH,Cluster-2400.0,2,Transcription activator. Involved in molecular mechanisms regulating shoot apical meristem (SAM) formation during embryogenesis and organ separation. Required for axillary meristem initiation and separation of the meristem from the main stem. May act as an inhibitor of cell division.
ATC1_DROME|ATC1_ANOGA,Cluster-22560.0,2,This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.|This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.
HIP32_ARATH,Cluster-55647.7,5,Heavy-metal-binding protein.
STP14_ARATH,Cluster-44754.0,7,Mediates an active uptake of hexoses; probably by sugar/hydrogen symport.
TCP9_ARATH,Cluster-39966.0,4,Component of the chaperonin-containing T-complex (TRiC); a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis.
TBB1_AVESA|TBB2_ELEIN,Cluster-35944.0,3,Tubulin is the major constituent of microtubules. It binds two moles of GTP; one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.|Tubulin is the major constituent of microtubules. It binds two moles of GTP; one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
SWET7_ARATH|SWET5_ARATH,Cluster-57115.1,4,Mediates both low-affinity uptake and efflux of sugar across the plasma membrane.|Mediates both low-affinity uptake and efflux of sugar across the plasma membrane (By similarity). May play roles in nurturing the male gametophyte (PubMed:25988582).
SWET5_ORYSJ|SWET7_ARATH,Cluster-57115.0,4,Mediates both low-affinity uptake and efflux of sugar across the plasma membrane (By similarity). Can transport galactose. Prevents growth but promotes senescence (PubMed:25988582; PubMed:24709840). Involved in regulating the crosstalk between sugar and auxin. Regulates negatively the auxin signaling pathway and translocation (PubMed:24709840).|Mediates both low-affinity uptake and efflux of sugar across the plasma membrane.
SWET5_ORYSJ,Cluster-57115.2,6,Mediates both low-affinity uptake and efflux of sugar across the plasma membrane (By similarity). Can transport galactose. Prevents growth but promotes senescence (PubMed:25988582; PubMed:24709840). Involved in regulating the crosstalk between sugar and auxin. Regulates negatively the auxin signaling pathway and translocation (PubMed:24709840).
LDOX_PETHY,Cluster-52599.0,3,Oxidation of leucoanthocyanidins into anthocyanidins.
SK_SOLLC|SK1_ARATH,Cluster-56889.0,2,Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
Y3209_ORYSJ,Cluster-23948.0,4,NA
TGT3B_ARATH,Cluster-36796.0,1,Probable transcription factor that may play a role in the induction of CAM4 in response to pathogen and salt.
ALD1_ARATH|TCP20_ARATH,Cluster-50537.0,5,Aminotransferase involved in local and systemic acquired resistance (SAR) to the bacterial pathogen P.syringae. Required for salicylic acid (SA) and camalexin accumulation upon pathogen infection. Possesses aminotransferase activity in vitro and may generate amino-acid-derived defense signals in vivo. May be involved in ethylene-induced senescence signaling. Involved in the biosynthesis of pipecolate (Pip); a metabolite that orchestrates defense amplification; positive regulation of SA biosynthesis; and priming to guarantee effective local resistance induction and the establishment of SAR (PubMed:23221596; PubMed:27758894). Converts lysine to alpha-keto-epsilon-aminocaproate; which then can spontaneously cyclize to form delta-(1)-piperideine-2-carboxylate (P2C). P2C is converted to Pip by SARD4 (PubMed:27758894). May produce non-Pip metabolites that play roles in immunity. Involved in the synthesis of distinct metabolite signals that affect basal and early defenses; and later defense responses (PubMed:25372120).|Transcription factor that binds to the site II motif (3'-TGGGCC/T-5') in the promoter of PCNA-2 and to 3'-GCCCG/A-5' elements in the promoters of cyclin CYCB1-1 and ribosomal protein genes.
SMR13_ARATH,Cluster-32934.0,5,Probable cyclin-dependent protein kinase (CDK) inhibitor that functions as a repressor of mitosis in the endoreduplication cell cycle.
PRPX_HORVU,Cluster-49569.0,1,NA
XTH15_ARATH,Cluster-33811.0,4,Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers; an essential constituent of the primary cell wall; and thereby participates in cell wall construction of growing tissues. Has a high XET activity; but little or no XEH activity in vitro. Acceptor preferences are XXXGol > XLLGol = XLFGol > XXLGol > XXFGol.
GLGL1_ARATH,Cluster-31567.0,2,This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor; ADP-glucose from Glc-1-P and ATP.
C83B1_ARATH,Cluster-28269.0,5,Involved in the metabolism of aromatic oximes. Catalyzes the oxime metabolizing step in indole glucosinolate biosynthesis by converting indole-3-acetaldoxime into indole-3-S-alkyl-thiohydroximate. Probably required for glucosinolate activation in response to pathogens. Functions in auxin homeostasis because indole-3-acetaldoxime also serves as a precursor for auxin biosynthesis. Specifically metabolizes (E)-p-hydroxyphenylacetaldoxime into an S-alkyl-thiohydroximate (PubMed:26361733).
PME41_ARATH|PME7_ARATH,Cluster-37255.0,2,Acts in the modification of cell walls via demethylesterification of cell wall pectin.|Acts in the modification of cell walls via demethylesterification of cell wall pectin.
PME2_CITSI|PME17_ARATH,Cluster-33843.0,5,Acts in the modification of cell walls via demethylesterification of cell wall pectin.|Acts in the modification of cell walls via demethylesterification of cell wall pectin.
PP143_ARATH,Cluster-57135.0,2,NA
IQD14_ARATH|IQD31_ARATH,Cluster-46461.0,4,|Guanine nucleotide exchange factor for ARF1 and ARF6 (PubMed:24058294). Guanine nucleotide exchange factor activity is enhanced by lipid binding (PubMed:24058294). Accelerates GTP binding by ARFs of all three classes. Guanine nucleotide exchange protein for ARF6; mediating internalisation of beta-1 integrin.
4CGT_ANTMA,Cluster-36083.3,1,Glycosyltransferase involved in the biosynthesis of aurones; plant flavonoids that provide yellow coloration to flowers.
4CGT_ANTMA,Cluster-36083.18,1,Glycosyltransferase involved in the biosynthesis of aurones; plant flavonoids that provide yellow coloration to flowers.
GDIR_ARATH,Cluster-54030.0,5,Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them; and the subsequent binding of GTP to them.
NUDT8_ARATH,Cluster-54850.0,5,Probably mediates the hydrolysis of some nucleoside diphosphate derivatives (By similarity). May be involved in plant immunity and act as a positive regulator of defense response through salicylic acid (SA) signaling (PubMed:25436909).
AIR3_ARATH,Cluster-35366.0,5,Serine protease. Has a substrate preference for the hydrophobic residues Phe and Ala and the basic residue Asp in the P1 position; and for Asp; Leu or Ala in the P1' position. May play a role in the degradation of structural proteins in the extracellular matrix of cells located above sites of lateral root formation and thus facilitate lateral root emergence.
GUN17_ARATH,Cluster-38603.8,5,Involved in active uptake of glycerol driven by electrogenic proton symport.
BBE18_ARATH|CBDAS_CANSA,Cluster-2971.24,3,|Catalyzes the stereoselective oxidative cyclization of the monoterpene moiety in cannabigerolic acid (CBGA); producing cannabidiolate (CBDA); the major cannabioid in fiber-type Cannabis plants. Can also use cannabinerolic acid as substrate; but not cannabigerol or cannabinerol.
RLA0_SOYBN|RPB1_MOUSE,Cluster-10846.1,2,Ribosomal protein P0 is the functional equivalent of E.coli protein L10.|DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together with the second largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB1 is part of the core element with the central large cleft; the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template. At the start of transcription; a single-stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol II. A bridging helix emanates from RPB1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol II by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition. During transcription elongation; Pol II moves on the template as the transcript elongates (By similarity). Elongation is influenced by the phosphorylation status of the C-terminal domain (CTD) of Pol II largest subunit (RPB1); which serves as a platform for assembly of factors that regulate transcription initiation; elongation; termination and mRNA processing (By similarity). Regulation of gene expression levels depends on the balance between methylation and acetylation levels of tha CTD-lysines (PubMed:26687004). Initiation or early elongation steps of transcription of growth-factors-induced immediate early genes are regulated by the acetylation status of the CTD (PubMed:24207025). Methylation and dimethylation have a repressive effect on target genes expression (PubMed:26687004).
GGT_QUERO|CGT_FRAAN,Cluster-51035.0,2,|Broad spectrum multifunctional glucosyltransferase. Catalyzes the formation of cinnamic acid and p-coumaric acid glucose esters during fruit ripening. Accepted substrates range from derivatives of cinnamic acid and benzoic acid to heterocyclic and aliphatic compounds; resulting in the formation of O- and S-glucose esters and O-glucosides. May also be involved in detoxification of xenobiotics.
FLUG_EMENI,Cluster-27961.0,1,May function as a GSI-related enzyme in synthesizing a small diffusible factor that acts as an extracellular signal directing asexual sporulation and perhaps other aspects of colony growth. May be involved in brlA activation (an early transcriptional regulator for conidiation specific gene).
U7A15_MALDO,Cluster-29300.0,1,Glycosyltransferase that possesses chalcone and flavonol 2'-O-glycosyltransferase activity. Converts phloretin to phlorizin (phloretin 2'-O-glucoside); a potent antioxidant. Possesses glycosyltransferase activity toward; naringenin; naringenin chalcone; eriodictyol; eriodictyol chalcone; apigenin; luteolin; kaempferol; quercetin; isoliquiritigenin; butein and caffeic acid. Can convert phloretin to phloretin 4'-O-glucoside and phloretin 4-O-glucoside.
PKS2_RUBID,Cluster-41441.0,2,Probable polyketide synthase (By similarity). May be involved in the process of cell migration.
RHF2A_ARATH|RHF1A_ARATH,Cluster-29116.0,7,E3 ubiquitin-protein ligase involved in the positive regulation of the gametogenesis progression. Required for the degradation of KRP6; a cyclin-dependent kinase inhibitor which accumulates during meiosis and blocks the progression of subsequent mitoses during gametophytes development. Functions in association with RHF1A.|E3 ubiquitin-protein ligase involved in the positive regulation of the gametogenesis progression. Mediates the proteasomal degradation of KRP6; a cyclin-dependent kinase inhibitor which accumulates during meiosis and blocks the progression of subsequent mitoses during gametophyte development. Functions in association with RHF2A (PubMed:18552199). Possesses E3 ubiquitin-protein ligase activity when associated with the E2 enzyme UBC8 in vitro (PubMed:15644464).
NIK1_ARATH|NIK2_ARATH,Cluster-48893.0,6,Involved in defense response to geminivirus and begomovirus infection via regulation of the nuclear trafficking of RPL10A. Phosphorylates RPL10A in vitro (PubMed:15489295; PubMed:18789471; PubMed:19112492; PubMed:19492062; PubMed:25707794). Activation of NIK1 downregulates cytosolic translation (PubMed:25707794).|Involved in defense response to geminivirus infection (By similarity). Phosphorylates RPL10A in vitro.
PTR27_ARATH,Cluster-48575.0,4,NA
FK172_ARATH,Cluster-32729.0,2,PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
KRP6_ORYSJ,Cluster-40909.0,4,Binds and inhibits CYCD2-1/CDKA-1 complex kinase activity. May target specifically CDKA-1.
ADS3_ARATH,Cluster-41094.2,6,NA
LOX15_SOLTU,Cluster-56181.4,7,Plant lipoxygenases may be involved in a number of diverse aspects of plant physiology including growth and development; pest resistance; and senescence or responses to wounding. May contribute to cell death during the hypersensitive response (HR) by the massive production of free fatty acid hydroperoxides. Catalyzes the hydroperoxidation of lipids containing a cis;cis-1;4-pentadiene structure.
WOX9_ARATH,Cluster-17577.0,2,Homeodomain transcription factor required for meristem growth and early development (PubMed:15753038). Promotes cell proliferation and prevents premature differentiation in meristematic tissues during postembryonic development (PubMed:15753038). Essential for maintaining tissue growth during embryogenesis (PubMed:17706632). May act by repressing TSS to promote meristematic proliferation (PubMed:21185286). Involved in the transcriptional activation of a subset of cytokinin response factors (PubMed:20110319). May act as a negative regulator of cytokinin signaling in the dark (PubMed:21057190).
ABI5_ARATH,Cluster-51373.0,4,Participates in ABA-regulated gene expression during seed development and subsequent vegetative stage by acting as the major mediator of ABA repression of growth. Binds to the embryo specification element and the ABA-responsive element (ABRE) of the Dc3 gene promoter and to the ABRE of the Em1 and Em6 genes promoters. Can also trans-activate its own promoter; suggesting that it is autoregulated. Plays a role in sugar-mediated senescence.
TMN11_ARATH,Cluster-48343.0,5,NA
ROGF3_ARATH|ROGF2_ARATH,Cluster-16591.1,2,Guanine-nucleotide exchange factor (GEF) that acts as an activator of Rop (Rho of plants) GTPases by promoting the exchange of GDP for GTP.|Guanine-nucleotide exchange factor (GEF) that acts as an activator of Rop (Rho of plants) GTPases by promoting the exchange of GDP for GTP.
RADL5_ARATH|RADL6_ARATH,Cluster-32347.0,7,Probable transcription factor.|Probable transcription factor.
PR4_PHAVU,Cluster-25403.0,6,NA
C94A1_VICSA|C86B1_ARATH,Cluster-30150.0,2,Catalyzes the omega-hydroxylation of various fatty acids (FA) from 10 to 18 carbon atoms. The substrate specificity is higher for laurate > palmitate > myristate > linolenate > linoleate > oleate > caprate. May play a minor role in cutin synthesis and could be involved in plant defense.|Involved in very long chain fatty acids (VLCFA) omega-hydroxylation. Required for the synthesis of saturated VLCFA alpha; omega-bifunctional suberin monomers.
BRXL1_ARATH|BRX_ARATH,Cluster-57098.1,1,May act as a regulator of cell proliferation and elongation in the root.|
CLC1_ARATH,Cluster-36123.0,5,Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
DCAM4_ARATH,Cluster-42795.1,5,NA
GDL61_ARATH,Cluster-56291.9,7,NA
PME62_ARATH,Cluster-2140.0,5,Pectinesterase required for cell type-specific pectin degradation to separate microspores.
1A1C_SOYBN|1A11_CUCPE,Cluster-8233.0,5,Catalyzes the formation of 1-aminocyclopropane-1-carboxylate; a direct precursor of ethylene in higher plants.|Catalyzes the formation of 1-aminocyclopropane-1-carboxylate; a direct precursor of ethylene in higher plants.
TM205_MOUSE,Cluster-40277.0,4,Enzyme catalyzing the degradation of lysoplasmalogen. Lysoplasmalogens are formed by the hydrolysis of the abundant membrane glycerophospholipids plasmalogens. May control the respective levels of plasmalogens and lysoplasmalogens in cells and modulate cell membrane properties.
PSAEA_NICSY|PSAE_SPIOL,Cluster-34944.0,2,Stabilizes the interaction between PsaC and the PSI core; assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase.|Stabilizes the interaction between PsaC and the PSI core; assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase.
NLTP2_SOLLC,Cluster-27544.0,1,Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
NLTP_VIGUN,Cluster-29917.0,1,Potential lipid transfer protein.
Y3081_ARATH,Cluster-40829.0,5,NA
HSP72_SOLLC|HSP7C_PETHY,Cluster-29880.0,7,|Molecular chaperone implicated in a wide variety of cellular processes; including protection of the proteome from stress; folding and transport of newly synthesized polypeptides; activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system; ensuring the correct folding of proteins; the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding; ATP hydrolysis and ADP release; mediated by co-chaperones. The co-chaperones have been shown to not only regulate different steps of the ATPase cycle of HSP70; but they also have an individual specificity such that one co-chaperone may promote folding of a substrate while another may promote degradation. The affinity of HSP70 for polypeptides is regulated by its nucleotide bound state. In the ATP-bound form; it has a low affinity for substrate proteins. However; upon hydrolysis of the ATP to ADP; it undergoes a conformational change that increases its affinity for substrate proteins. HSP70 goes through repeated cycles of ATP hydrolysis and nucleotide exchange; which permits cycles of substrate binding and release. The HSP70-associated co-chaperones are of three types: J-domain co-chaperones HSP40s (stimulate ATPase hydrolysis by HSP70); the nucleotide exchange factors (NEF) such as BAG1/2/3 (facilitate conversion of HSP70 from the ADP-bound to the ATP-bound state thereby promoting substrate release); and the TPR domain chaperones such as HOPX and STUB1. Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. Binds bacterial lipopolysaccharide (LPS) and mediates LPS-induced inflammatory response; including TNF secretion. Participates in the ER-associated degradation (ERAD) quality control pathway in conjunction with J domain-containing co-chaperones and the E3 ligase STUB1.
CYCLD_ANTMA,Cluster-53500.0,5,Involved in the dorsovental asymmetry of flowers. Retards growth rate and reduces organ number in the dorsal region of flowers. Binds specifically to the DNA sequence 5'-GGNCCCNC-3'; and is able to bind to the RAD promoter sequence in vivo.
ACCO_ACTDE|ACCO1_PETHY,Cluster-50017.1,5,Serine/threonine-protein kinase with low activity.|
5MAT1_SALSN,Cluster-49321.0,1,Catalyzes the transfer of a malonyl group from malonyl-CoA to the 6'''-hydroxyl group of the 5-glucosyl moiety of anthocyanins. Active towards bisdemalonylsalvianin (pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside) and shisonin; but not towards nodemalonylsalvianin; salvianin; pelargonidin 3;5-diglucoside and delphinidin 3;5-diglucoside.
AB22G_ARATH,Cluster-46779.0,3,NA
AB22G_ARATH,Cluster-29177.0,1,NA
DCTP1_RAT,Cluster-31791.0,5,Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.
GRXC9_ARATH,Cluster-37832.0,6,Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
GT14B_ARATH,Cluster-28431.2,5,Beta-glucuronosyltransferase involved in the biosynthesis of type II arabinogalactan (AG). Modifies both the beta-1;6-linked galactan and beta-1;3-linked galactan present in type II AG.
GT14B_ARATH,Cluster-28431.4,6,Beta-glucuronosyltransferase involved in the biosynthesis of type II arabinogalactan (AG). Modifies both the beta-1;6-linked galactan and beta-1;3-linked galactan present in type II AG.
NAC22_ARATH|NAC98_ARATH,Cluster-37391.0,4,Transcriptional activator that mediates auxin signaling to promote lateral root development. Activates the expression of two downstream auxin-responsive genes; DBP and AIR3.|Transcription activator of STM and KNAT6. Involved in molecular mechanisms regulating shoot apical meristem (SAM) formation during embryogenesis and organ separation. Required for the fusion of septa of gynoecia along the length of the ovaries. Activates the shoot formation in callus in a STM-dependent manner. Controls leaf margin development and required for leaf serration. Involved in axillary meristem initiation and separation of the meristem from the main stem. Regulates the phyllotaxy throughout the plant development. Seems to act as an inhibitor of cell division.
AX10A_SOYBN,Cluster-38260.0,4,Catalyzes the hydrolysis of sphingomyelin. May also act on other phosphatidyl esters. Induces complement-dependent hemolysis and dermonecrosis.
AB1K1_ARATH,Cluster-29537.0,2,Kinase that can phosphorylates the tocopherol cyclase VTE1; a key enzyme of tocopherol (vitamin E) metabolism and involved in the recycling of oxidated alpha-tocopherol quinone; possibly stabilizing it at plastoglobules. Regulates also plastoglobule protein composition (PubMed:24267661). Prevents photodamage of chloroplasts under continuous red light; thus working in opposition to ABC1K3 (PubMed:25882344). Together with ABC1K1; contributes to plastoglobule (PG) function in prenyl-lipid metabolism; stress response; and thylakoid remodeling (PubMed:23673981; PubMed:24267661). Involved in chlorophyll degradation and in the maintenance of the number of chlorophyll-binding photosynthetic thylakoid membranes (PubMed:22447966). Ensures photosynthetic electron transport by regulating the homeostasis of plastoquinone; beta-carotene and xanthophyll lutein; as well as membrane antioxidant tocopherol metabolism (PubMed:24267661). Seems to affect specifically stability or turnover of D1 protein; product of psbA; one of the four core subunits of the photosystem II (PSII) (PubMed:25882344). Required for photooxidative stress responses; including the induction of oxidative stress response genes (e.g. FSD1; CSD1; CAT1; and UTG71C1); to prevent photosystem II core and chlorophyll degradations (PubMed:22447966; PubMed:23673981; PubMed:24267661).
IRX9_ARATH,Cluster-57545.0,4,Involved in the synthesis of the hemicellulose glucuronoxylan; a major component of secondary cell walls. Probably involved in the elongation of glucuronoxylan xylosyl backbone.
DMC1_SOYBN,Cluster-39380.0,4,May participate in meiotic recombination.
UCC1_ARATH|CPC_CUCSA,Cluster-40407.0,2,Catalyzes the hydrolysis of unsaturated hyaluronate and chondroitin disaccharides. Also degrades unsaturated heparin disaccharides. Releases 4-deoxy-4;5-didehydro D-glucuronic acid or 4-deoxy-4;5-didehydro L-iduronic acid from chondroitin disaccharides; hyaluronan disaccharides and heparin disaccharides and cleaves both glycosidic (1->3) and (1->4) bonds. Prefers sulfated glycosaminoglycans compared to unsulfated glycosaminoglycans. Probably required for mammalian cells invasion through the degradation of extracellular sulfated glycosaminoglycans such as chondroitin and hyaluronan.|Involved in the metabolism of ADP-ribose 1';2'-cyclic phosphate which is produced as a consequence of tRNA splicing.
UCC1_ARATH|ENL1_ARATH,Cluster-40407.2,2,Catalyzes the hydrolysis of unsaturated hyaluronate and chondroitin disaccharides. Also degrades unsaturated heparin disaccharides. Releases 4-deoxy-4;5-didehydro D-glucuronic acid or 4-deoxy-4;5-didehydro L-iduronic acid from chondroitin disaccharides; hyaluronan disaccharides and heparin disaccharides and cleaves both glycosidic (1->3) and (1->4) bonds. Prefers sulfated glycosaminoglycans compared to unsulfated glycosaminoglycans. Probably required for mammalian cells invasion through the degradation of extracellular sulfated glycosaminoglycans such as chondroitin and hyaluronan.|Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane; the endolysin can reach the periplasm and break down the peptidoglycan layer.
PRP2_ARATH|PRP4_ARATH,Cluster-54587.1,7,This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the rate-limiting conversions of tyrosine to DOPA; DOPA to DOPA-quinone and possibly 5;6 dihydroxyindole to indole-5'6 quinone.|Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly; and as component of the precatalytic spliceosome (spliceosome B complex).
MACP1_ARATH|SEC14_SCHPO,Cluster-55153.1,1,Negatively controls the salicylic acid (SA)-mediated pathway of programmed cell death in plant immunity.|Required for transport of secretory proteins from the Golgi complex. Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro. Essential for viability and secretion.|Has a direct role in controlling cell septation and in forespore membrane formation.
SAU50_ARATH,Cluster-43511.0,4,Effector of hormonal and environmental signals in plant growth.
PLMT_ARATH,Cluster-42085.0,5,Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis; the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC).
PME2_CITSI|PME54_ARATH,Cluster-39020.0,1,Acts in the modification of cell walls via demethylesterification of cell wall pectin.|Acts in the modification of cell walls via demethylesterification of cell wall pectin.
CAAT5_ARATH,Cluster-19557.0,2,NA
SY112_ARATH,Cluster-19236.0,2,Vesicle trafficking protein that functions in the secretory pathway.
MIZ1_ARATH,Cluster-45393.0,4,NA
ZPR3_ARATH,Cluster-39607.0,5,Competitive inhibitor of the HD-ZIPIII transcription factors in shoot apical meristem (SAM) development. Acts by forming non-functional heterodimers. Part of a negative feedback loop. Involved in SAM development and lateral organ patterning. Essential for proper functioning of stem cells in the SAM.
EDL16_ARATH|ERDL7_ARATH,Cluster-48767.0,1,Sugar transporter.|Sugar transporter.
AB25G_ARATH,Cluster-32465.0,5,Probably involved in redistribution of internalized aluminum. May mediate vacuolar sequestration of a metal complex.
TAR2_ARATH,Cluster-57369.0,5,Involved in auxin production. Both TAA1 and TAR2 are required for maintaining proper auxin levels in roots; while TAA1; TAR1 and TAR2 are required for proper embryo patterning. Involved in the maintenance of the root stem cell niches.
CDF2_ARATH,Cluster-45946.0,4,Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence (By similarity). Regulates a photoperiodic flowering response. Transcriptional repressor of 'CONSTANS' expression. The stability of CDF2 is controlled by 'GIGANTEA' and redundantly by ADO3; ADO2 and/or ADO1.
NRG2_ARATH,Cluster-53700.1,5,Required for nitrate signaling. Regulates expression of the nitrate-responsive genes NIA1; NIR1; NRT2.1 and NPF6.3/NRT1.1.
Y1723_ARATH,Cluster-30975.0,4,NA
5MAT1_SALSN,Cluster-19870.0,2,Catalyzes the transfer of a malonyl group from malonyl-CoA to the 6'''-hydroxyl group of the 5-glucosyl moiety of anthocyanins. Active towards bisdemalonylsalvianin (pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside) and shisonin; but not towards nodemalonylsalvianin; salvianin; pelargonidin 3;5-diglucoside and delphinidin 3;5-diglucoside.
BH144_ARATH|ALL9_OLEEU,Cluster-50881.0,2,|May act as a neurotransmitter or neuromodulator.
C93B1_GLYEC,Cluster-23212.0,2,NA
WRKY7_ARATH,Cluster-36639.2,5,Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'); a frequently occurring elicitor-responsive cis-acting element.
WRKY7_ARATH,Cluster-36639.1,5,Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'); a frequently occurring elicitor-responsive cis-acting element.
MARH8_MOUSE,Cluster-42564.6,4,E3 ubiquitin-protein ligase that mediates ubiquitination of CD86 and MHC class II proteins; such as HLA-DR alpha and beta; and promotes their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. May also promote ubiquitination and endocytosis of TFRC and FAS.
Y4929_FRASN|Y2020_MYCLE,Cluster-44598.0,1,|
PAN_ARATH|TGAL1_ORYSJ,Cluster-30566.1,5,Transcriptional activator involved in the determination of floral organ number. Acts to determine floral organ patterning by establishing floral organ primordia in specific numbers and positions. Plays a role in regulating stem cell fate by directly controlling AG expression. Binds to the 5'-AAGAAT-3' cis-acting element found in AG promoter. Might represent a target for a post-translational modification by GRXC7/ROXY1.|Transcriptional regulator involved in defense response.
Y1648_ARATH,Cluster-43807.0,7,NA
IDN2_ARATH,Cluster-42185.1,5,NA
GT14A_ARATH|GLFT_PICTO,Cluster-47354.0,4,Beta-glucuronosyltransferase involved in the biosynthesis of type II arabinogalactan (AG). Modifies both the beta-1;6-linked galactan and beta-1;3-linked galactan present in type II AG. Transfers glucuronate to beta-1;6-galactooligosaccharides with degrees of polymerization ranging from 3 to 11. Transfers glucuronate to beta-1;3-galactooligosaccharides with degrees of polymerization ranging from 5 to 7. The addition of glucuronate at the O6 position may terminate galactose chain extension. Required for cell elongation during seedling growth.|Catalyzes the transfer of the formyl group from N-formylglutamate to tetrahydrofolate (THF) to yield 5-formyltetrahydrofolate (5-CHO-THF) and glutamate (Glu). The triglutamate form of 5-CHO-THF (5-CHO-THF-Glu3) can also be used as substrate. It can also catalyzes the transfer of the formimino group from N-formiminoglutamate to tetrahydrofolate (THF) to yield 5-formiminotetrahydrofolate (5-NH=CH-THF) and glutamate (Glu). It can replace YgfA to catalyzes the irreversible ATP-dependent transformation of 5-CHO-THF to form 5;10-methenyltetrahydrofolate (5;10-CH=THF).
FTCD_MOUSE|FTCD_PIG,Cluster-47354.1,4,Folate-dependent enzyme; that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool.|Binds and promotes bundling of vimentin filaments originating from the Golgi.|Folate-dependent enzyme; that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool.|Binds and promotes bundling of vimentin filaments originating from the Golgi.
AAE_RAUSE,Cluster-35752.0,4,Deacetylates 17-O-acetylajmaline and 17-O-acetylnorajmaline; but is inactive toward other acetylated alkaloids.
AAE_RAUSE,Cluster-35752.2,4,Deacetylates 17-O-acetylajmaline and 17-O-acetylnorajmaline; but is inactive toward other acetylated alkaloids.
AAE_RAUSE,Cluster-31447.0,3,Deacetylates 17-O-acetylajmaline and 17-O-acetylnorajmaline; but is inactive toward other acetylated alkaloids.
SLK1_ARATH|SEUSS_ARATH,Cluster-31074.0,3,Probable transcription regulator that functions in the development of the carpel margin meristem similarly to SEUSS (SEU). In association with SEU; supports organ development from meristematic regions by facilitating auxin response and thus organ initiation; and by sustaining meristematic potential through the maintenance of PHABULOSA expression (PubMed:20007451). DNA-binding adapter subunit of the SEU-SLK1 transcriptional corepressor of abiotic stress (e.g. salt and osmotic stress) response genes (PubMed:24564815).|DNA-binding adapter subunit of the SEU-LUG transcriptional corepressor of the C class floral homeotic gene AGAMOUS during the early stages of floral meristem development. Is part of the A class cadastral complex that define the boundaries between the A and C class homeotic genes expression and function. Interacts together with APETALA2 and LEUNIG to repress AGAMOUS expression. In association with LUG; regulates petal shape through AGAMOUS-independent mechanisms. Controls cell division during petal development and enable the proper patterning of petal blade vasculature. Required for the proper elaboration of petal polarity along the adaxial/abaxial axis. May act through direct or indirect regulation of PHABULOSA and YAB1 and thus regulate cellular proliferation within the developing petal blade. In association with AINTEGUMENTA (ANT); coordinates patterning cues and cellular proliferation along the three positional axes of the developing gynoecium. Required for the development of the medial ridge and subsequent ovule initiation.
PPA27_ARATH,Cluster-57268.0,1,May dephosphorylate thiamine phosphates.
NLTPC_RICCO,Cluster-22742.0,5,Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
VILI3_ARATH,Cluster-29342.6,4,Binds actin and actin filament bundles in a Ca(2+)-insensitive manner; but severs actin filaments in a calcium-dependent manner; regardless of the presence or not of VLN1 (AC O81643). Acts redundantly with VLN2 (AC O81644) to generate thick actin filament bundles; to regulate directional organ growth (PubMed:22209875) and in sclerenchyma development (PubMed:22563899).
UGT2_GARJA,Cluster-38028.1,3,Iridoid glucosyltransferase acting on genipin and 7-deoxyloganetin. No activity with 7-deoxyloganetic acid. Involved in geniposide biosynthesis.
UGT2_GARJA,Cluster-38028.0,1,Iridoid glucosyltransferase acting on genipin and 7-deoxyloganetin. No activity with 7-deoxyloganetic acid. Involved in geniposide biosynthesis.
UGT2_GARJA,Cluster-38028.2,1,Iridoid glucosyltransferase acting on genipin and 7-deoxyloganetin. No activity with 7-deoxyloganetic acid. Involved in geniposide biosynthesis.
SERC3_HUMAN|SERC3_PONAB,Cluster-52881.0,3,Restriction factor required to restrict infectivity of lentiviruses; such as HIV-1: acts by inhibiting an early step of viral infection. Impairs the penetration of the viral particle into the cytoplasm (PubMed:26416733; PubMed:26416734).|Restriction factor required to restrict infectivity of gammaretroviruses: acts by inhibiting early step of viral infection and impairing the ability of the viral particle to translocate its content to the cytoplasm.
SCP40_ARATH|CBP23_HORVU,Cluster-57552.0,2,Probable carboxypeptidase.|
BBE13_ARATH,Cluster-54899.0,4,Mediates oxidation of cinnamyl alcohol and of p-hydroxylated derivatives of cinnamyl alcohol (i.e. the monolignols p-coumaryl-; coniferyl-; and sinapyl alcohol) to their corresponding aldehydes. Can use cinnamyl alcohol and derivatives; as well as beta-O-glycosylated form of coniferyl alcohol (coniferin) as substrate.
SILD_FORIN,Cluster-29775.2,1,Oxidoreductase involved in lignan biosynthesis. Catalyzes the stereospecific conversion of (-)-secoisolariciresinol to (-)-matairesinol via a lactol intermediate.
ATH1_ARATH,Cluster-38175.3,5,Transcription factor which may be involved in the signal transduction pathway downstream of the COP1 gene. Controls floral competency as a specific activator of FLC expression. Is responsive of the nuclear import of SHOOT MERISTEMLESS (STM).
MYSA_DROME,Cluster-1970.0,2,Muscle contraction.
ACA9_ARATH,Cluster-26967.0,6,This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol out of the cell or into organelles.
U76B1_ARATH|U76C3_ARATH,Cluster-29346.0,2,Glycosylates the amino acid-related molecules isoleucic acid (2-hydroxy-3-methylpentanoic acid) and valic acid (2-hydroxy-3-methylbutyric acid). Acts as a negative regulator of salicylic acid (SA)-dependent plant defense in the absence of pathogens and promotes the jasmonate (JA) response. Negatively influences the onset of senescence.|Possesses low quercetin 7-O-glucosyltransferase activity in vitro.
UFO_ARATH,Cluster-34389.0,5,Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes; which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Considered as a meristem identity factor required for normal growth of the young floral meristem. Acts together with LEAFY to positively regulate the B class floral homeotic genes APETALA3 and PISTILLATA. In this way; operates as a region-specific regulator for petal and stamen development. Alternatively; may play a role as a negative regulator of the C class floral homeotic genes. Interacts together with the SKP1-like protein ASK1 to form a ubiquitin E3 ligase complex and could indirectly promote the ubiquitination and degradation of specific proteins controlling the floral primordia development like repressors of B class floral homeotic genes.
CNGC8_ARATH|CNGC7_ARATH,Cluster-44328.0,5,Putative cyclic nucleotide-gated ion channel.|Putative cyclic nucleotide-gated ion channel.
AVT1H_ARATH,Cluster-40652.0,4,NA
PMA8_ARATH,Cluster-43373.1,7,The plasma membrane H(+) ATPase of plants and fungi generates a proton gradient that drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.
PMA8_ARATH,Cluster-25280.0,4,The plasma membrane H(+) ATPase of plants and fungi generates a proton gradient that drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.
CHSY_ANTMA|PKS1_RUBID,Cluster-6599.9,2,The primary product of this enzyme is 4;2';4';6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.|Polyketide synthase producing naringenin chalcone and slightly p-coumaryltriacetic acid lactone (CTAL). Can use p-coumaryl-CoA as substrate.
BGLC_OLEEU,Cluster-33503.4,2,Major beta-glucosidase activating oleuropein into a potent protein cross-linking agent (PubMed:25697790; PubMed:28483880). No activity with rutin; luteolin or p-nitrophenyl-beta-glucopyranoside as substrates (PubMed:25697790).
BGLC_OLEEU,Cluster-33503.3,3,Major beta-glucosidase activating oleuropein into a potent protein cross-linking agent (PubMed:25697790; PubMed:28483880). No activity with rutin; luteolin or p-nitrophenyl-beta-glucopyranoside as substrates (PubMed:25697790).
APA1_ARATH,Cluster-42491.0,6,Involved in the breakdown of propeptides of storage proteins in protein-storage vacuoles (By similarity). Possesses aspartic protease activity in vitro.
HSBH1_SOYBN|LET6_SOLLC,Cluster-23366.0,5,Possible transcription activator involved in early embryonic development. Probably binds to the DNA sequence 5'-TGAC-3'.|May have a role to play in formative events in ovule and embryo morphogenesis. Probably binds to the DNA sequence 5'-TGAC-3'.
40G3_ORYSJ,Cluster-51740.0,4,Lectin which binds carbohydrates in vitro. Interacts through its lectin domain with glycan structures containing specific motifs.
SNL6_ORYSJ|DFRA_MALDO,Cluster-41096.0,3,Involved in defense response. Required for NPR1/NH1-mediated resistance to the bacterial blight pathogen Xanthomomas oryzae pv. oryzae (Xoo). Required for pathogenesis-related (PR) genes expression. May be involved in lignin biosynthesis.|Bifunctional enzyme involved in flavonoid metabolism. May use dihydroquercetin; dihydrokaempferol; eriodictyol; garbanzol (5-deoxydihydrokaempferol); dihydrofisetin (5-deoxydihydroquercetin); naringenin to a low extent (10%); but not 5-deoxynaringenin or butin (5-deoxyeriodictyol) as substrate.
BON3_ARATH,Cluster-30219.0,5,Negative regulator of cell death and defense responses. Repress a number of R genes and may have effects in promoting growth and development. May function in membrane trafficking and in fusion of vesicles with plasma membrane.
UBC29_ARATH|UBC5A_ORYSJ,Cluster-34959.0,4,Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.|E2 conjugating enzyme that associates with the E3 ubiquitin-protein ligase EL5 to mediates ubiquitination of target proteins.
GATL4_ARATH,Cluster-38849.0,5,May be involved in pectin and/or xylans biosynthesis in cell walls.
EDR2_ARATH,Cluster-53689.0,4,Negative regulator of the salicylic acid- (SA-) mediated resistance to pathogens; including the biotrophic powdery mildew pathogens Golovinomyces cichoracearum and Blumeria graminis; and the downy mildew pathogen Hyaloperonospora parasitica; probably by limiting the initiation of cell death and the establishment of the hypersensitive response (HR). Prevents ethylene-induced senescence. Binds to phosphatidylinositol-4-phosphate (PtdIns(4)P) in vitro.
LRL12_ARATH,Cluster-26714.0,6,NA
CLSY3_ARATH|CLSY4_ARATH,Cluster-20696.0,5,Probable chromatin remodeling factor.|Probable chromatin remodeling factor.
E70A1_ARATH,Cluster-33191.0,5,Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane during regulated or polarized secretion. Involved in polarized cell growth and organ morphogenesis. Involved in polarized cell growth and organ morphogenesis. During cytokinesis; involved in cell plate initiation; cell plate maturation and formation of new primary cell wall. Participates in polarized pectin delivery required for the polarized development of the mucilage-producing volcano cells of the seed coat. Involved in the recycling and localization of auxin efflux carriers PIN1 and PIN2; and thus in polar auxin transport regulation. Functions in vesicle trafficking in tracheary elements to regulate patterned secondary cell wall thickening.
C3H18_ARATH,Cluster-32879.0,6,NA
MLO1_ARATH,Cluster-30347.0,4,May be involved in modulation of pathogen defense and leaf cell death. Activity seems to be regulated by Ca(2+)-dependent calmodulin binding and seems not to require heterotrimeric G proteins.
CM1_ARATH|Y5332_ARATH,Cluster-56416.0,1,|
PLY15_ARATH,Cluster-32677.1,5,NA
FLZ6_ARATH,Cluster-40629.0,5,May act as an adapter to facilitate the interaction of SnRK1 complex with effector proteins; conferring tissue- and stimulus-type specific differences in the SnRK1 regulation pathway (PubMed:24600465). Negatively regulates KIN10 leading to a repression of the SnRK1 signaling pathway (PubMed:29406622).
IQM4_ARATH,Cluster-52880.0,3,May be involved in biotic and abiotic stress responses.
BOR4_ARATH,Cluster-44926.0,5,Efflux-type boron transporter polarly localized in roots. Boron is essential for maintaining the integrity of plants cell walls.
TET15_ARATH,Cluster-7912.0,7,May be involved in the regulation of cell differentiation.
PFPB_RICCO,Cluster-43721.0,7,Catalytic subunit of pyrophosphate--fructose 6-phosphate 1-phosphotransferase. Catalyzes the phosphorylation of D-fructose 6-phosphate; the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs); which renders the reaction reversible; and can thus function both in glycolysis and gluconeogenesis.
C3H49_ARATH,Cluster-26022.0,2,NA
CAR4_ARATH,Cluster-40110.0,1,Mediates the transient calcium-dependent interaction of PYR/PYL/RCAR abscisic acid (ABA) receptors with the plasma membrane and thus regulates ABA sensitivity (PubMed:26719420; PubMed:25465408). Stimulates the GTPase/ATPase activities of YchF1; and regulates its subcellular localization. Promotes tolerance towards salinity stress by limiting the accumulation of reactive oxygen species (ROS) (PubMed:23550829). Promotes resistance to bacterial pathogens (e.g. Xanthomonas oryzae pv. oryzae and P. syringae pv. tomato DC3000) (By similarity). Binds liposomes in the absence of exogenous Ca(2+); but this activity is enhanced in the presence of Ca(2+) and generates membrane curvature (PubMed:26719420).
PLY21_ARATH,Cluster-57729.1,4,NA
PALY_DIGLA,Cluster-49355.0,3,This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton.
TL16_ARATH,Cluster-39696.0,2,NA
GAE2_ARATH,Cluster-25172.0,4,Involved in the synthesis of the negatively charged monosaccharide that forms the backbone of pectic cell wall components.
4CLL7_ARATH,Cluster-56228.0,4,NA
SSL10_ARATH,Cluster-51369.0,1,Catalyzes the stereospecific condensation of tryptamine with secologanin to form strictosidine; the key intermediate of indole alkaloid biosynthesis.
HIP8_ARATH|HIP7_ARATH,Cluster-55693.0,5,Heavy-metal-binding protein.|
MES8_ARATH|PNAE_RAUSE,Cluster-55837.0,2,Methylesterase shown to have carboxylesterase activity in vitro.|
VESTR_MEDSA,Cluster-26767.0,4,Stereospecific enzyme that catalyzes the NADPH-dependent reduction of (3R)-vestitone to (3R;4R)-4'-methoxyisoflavan-2';4;7-triol (DMI). Has no activity with (3S)-vestitone. Catalyzes the penultimate step in the biosynthesis of the phytoalexin medicarpin; and thereby contributes to plant defense reactions.
CA4_ARATH|AGL65_ARATH,Cluster-44352.0,2,The light-harvesting complex (LHC) functions as a light receptor; it captures and delivers excitation energy to photosystems with which it is closely associated.|Probable transcription factor that forms a heterodimer with the MADS-box protein AGL104 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth.
FBL4_ARATH,Cluster-44414.0,3,NA
GRXC8_ARATH,Cluster-50370.0,5,Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity). Involved in flower development.
IBL1_ARATH,Cluster-45227.0,4,Functions redundandly with IBH1/BHLH158 in a regulation node known as the incoherent feed-forward loop (FFL). Acts as transcriptional repressor that negatively regulates cell and organ elongation in response to gibberellin (GA) and brassinosteroid (BR) signaling.
NPC3_ARATH|ATL51_ARATH,Cluster-46295.0,4,Possesses specific phosphatase activity toward lysophosphatidic acid (LPA) in vitro. Does not show phospholipase C activity. May play a role in signal transduction and storage lipid synthesis. May be involved in brassinolide-mediated signaling in root development.|
EPFL2_ARATH,Cluster-49670.0,2,Controls stomatal patterning.
GDPD1_ARATH|GDPD2_ARATH,Cluster-51722.0,2,|Has glycerophosphoinositol inositolphosphodiesterase activity and specifically hydrolyzes glycerophosphoinositol; with no activity for other substrates such as glycerophosphoinositol 4-phosphate; glycerophosphocholine; glycerophosphoethanolamine; and glycerophosphoserine. Accelerates the program of osteoblast differentiation and growth. May play a role in remodeling of the actin cytoskeleton.
TPRL2_ERYCB,Cluster-17130.2,2,Has no tropinone reductase activity.
ALDH_CRAPL|AL3H1_ARATH,Cluster-56548.0,4,|
ALDH_CRAPL,Cluster-55543.0,5,NA
JUGN4_JUGNI|11SB_CUCMA,Cluster-47812.0,4,Seed storage protein.|This is a seed storage protein.
RAD_ANTMA,Cluster-49142.0,5,Involved in the dorsovental asymmetry of flowers. Promotes dorsal identity.
NAC98_ARATH,Cluster-39422.0,5,Transcription activator of STM and KNAT6. Involved in molecular mechanisms regulating shoot apical meristem (SAM) formation during embryogenesis and organ separation. Required for the fusion of septa of gynoecia along the length of the ovaries. Activates the shoot formation in callus in a STM-dependent manner. Controls leaf margin development and required for leaf serration. Involved in axillary meristem initiation and separation of the meristem from the main stem. Regulates the phyllotaxy throughout the plant development. Seems to act as an inhibitor of cell division.
DSP1_ARATH,Cluster-36938.0,5,Possesses phosphotyrosine phosphatase activity in vitro. Hydrolyzes para-nitrophenyl phosphate in vitro (PubMed:21409566; PubMed:18433060). Hydrolyzes O-methylfluorescein phosphate in vitro (PubMed:21409566). Hydrolyzes polyphosphate and ATP in vitro (PubMed:18433060). Dephosphorylates the phosphoinositides PI(3;4;5)P3; PI(3;5)P2; but not PI(3)P; PI(3;4)P2 or PI(4;5)P2 (PubMed:17976645).
DTX54_ARATH,Cluster-23325.0,2,NA
USPAL_ARATH,Cluster-32634.0,4,Required for resistance to DNA-damaging agents.
U89B2_STERE,Cluster-50239.1,3,May glycosylate diterpenes or flavonols in leaves.
C75A2_SOLME|C75A3_PETHY,Cluster-18047.0,2,|Catalyzes the 3'5'-hydroxylation of naringenin and eriodictyol to form 5;7;3;'4';5'-pentahydroxyflavanone and 3';5'-hydroxylation of dihydrokaempferol and dihydroquercetin to form dihydromyricetin.
UBC5_ARATH,Cluster-51719.0,1,Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.
NFD4_ARATH,Cluster-50624.0,1,Required for karyogamy during female gametophyte development; when the two polar nuclei fuse to form the diploid central cell nucleus (PubMed:16698901).
LET12_SOLLC|KNAT4_ARATH,Cluster-31843.0,7,May have a role to play in formative events in ovule and embryo morphogenesis.|
KNAT7_ARATH,Cluster-50439.0,4,May be involved in secondary cell wall biosynthesis.
HIP23_ARATH,Cluster-36133.0,4,Heavy-metal-binding protein.
14KD_DAUCA,Cluster-43063.0,5,NA
MY1R1_SOLTU,Cluster-45460.0,3,Binds selectively to the DNA sequence 5'-[GA]GATAA-3' and may act as a transcription factor involved in the regulation of drought-responsive genes. Enhances stomatal closure in response to abscisic acid (ABA). Confers drought and salt tolerance.
GDL15_ARATH,Cluster-53093.0,4,Involved in the control of the PYK10 complex size and possibly substrate specificity. May be exported from the endoplamic reticulum upon interaction with MVP1.
GLO1_ARATH|GOX_SPIOL,Cluster-47497.0,2,Photorespiratory enzyme that can exert a strong regulation over photosynthesis; possibly through a feed-back inhibition on Rubisco activase. Not required for oxalate accumulation.|
86A22_PETHY,Cluster-42792.0,4,Fatty acyl-CoA omega-hydroxylase essential for the production of omega-hydroxy fatty acids and the biosynthesis of triacylglycerol-/diacylglycerol-based estolide polyesters in the stigma. Substrate preference is 16:0-CoA > 18:1-CoA > 18:0-CoA.
KCS2_ARATH,Cluster-41554.0,2,NA
NO93_SOYBN,Cluster-42860.1,4,Exhibits cGTPase activity; binds and hydrolyzes specifically GTP (PubMed:18801746). May participate in ribosome assembly and stability and thus regulates protein synthesis in chloroplasts. The GTPase activity requires MgCl(2)and the presence of either KCl or (NH(4))(2)SO(4). Involved in the post-transcriptional regulation of the methylerythritol phosphate (MEP) pathway. Involved in chlorophyll-a fluorescence regulation.|May mediate the production or accumulation of nitric oxide (NO) which is a messenger molecule involved in hormonal signaling and defense responses in plant (PubMed:14526079; PubMed:16272429; PubMed:16690168 and PubMed:17351048). Acts as an antisenescence agent. Plays a crucial role in both extracellular calmodulin (ExtCaM)-triggered and salicylic acid (SA)-mediated H(2)O(2)-dependent stomatal closure.
MYB73_ARATH,Cluster-48682.0,7,Transcription factor that functions in salt stress response. Acts as negative regulator of NHX7/SOS1 and CBL4/SOS3 induction in response to salt stress (PubMed:23809151). In response to auxin; activates the transcription of the auxin-responsive gene IAA19. The IAA19 transcription activation by MYB73 is enhanced by direct interaction between MYB73 and PYL8 (PubMed:24894996).
GH36_ARATH,Cluster-37957.0,7,Catalyzes the synthesis of indole-3-acetic acid (IAA)-amino acid conjugates; providing a mechanism for the plant to cope with the presence of excess auxin. Strongly reactive with Glu; Gln; Trp; Asp; Ala; Leu; Phe; Gly; Tyr; Met; Ile and Val. Little or no product formation with His; Ser; Thr; Arg; Lys; or Cys. Also active on pyruvic and butyric acid analogs of IAA; PAA and the synthetic auxin naphthaleneacetic acid (NAA). The two chlorinated synthetic auxin herbicides 2;4-D and 3;6-dichloro-o-anisic acid (dicamba) cannot be used as substrates (PubMed:15659623). Involved in auxin signal transduction. Inhibits shoot and hypocotyl cell elongation; and lateral root cell differentiation in light (PubMed:11169197).
MAOC_ORYSJ,Cluster-53904.0,1,The chloroplastic ME isoform decarboxylates malate shuttled from neighboring mesophyll cells. The CO(2) released is then refixed by ribulose-bisphosphate carboxylase. This pathway eliminates the photorespiratory loss of CO(2) that occurs in most plants.
PRE1_ARATH,Cluster-45896.0,7,Atypical and probable non DNA-binding bHLH transcription factor that integrates multiple signaling pathways to regulate cell elongation and plant development. Binds IBH1; forming a pair of antagonistic bHLH transcription factors that function downstream of BZR1 to mediate brassinosteroid regulation of cell elongation. Regulates light responses by binding and inhibiting the activity of the bHLH transcription factor HFR1; a critical regulator of light signaling and shade avoidance. May have a regulatory role in various aspects of gibberellin-dependent growth and development.
AGO1A_ORYSJ|AGO5_ARATH,Cluster-51608.0,4,Probably involved in the RNA silencing pathway. May bind to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs); and represses the translation of mRNAs which are complementary to them.|Involved in RNA-mediated post-transcriptional gene silencing (PTGS). Main component of the RNA-induced silencing complex (RISC) that binds to a short guide RNA such as a microRNA (miRNA) or small interfering RNA (siRNA). RISC uses the mature miRNA or siRNA as a guide for slicer-directed cleavage of homologous mRNAs to repress gene expression. Associates with siRNAs of various sizes; from 21-24 nucleotide in length and preferentially recruits small RNAs with a 5' terminal cytosine. Probably involved in antiviral RNA silencing. Associates with siRNAs derived from cucumber mosaic virus (CMV). Targeted by the turnip yellows virus (TuYV) protein P0 (via F-box-like domain) for probable proteasome degradation and thereby inactivating AGO5 function in RNA silencing.
WRK44_ARATH|WRK46_HORVU,Cluster-35127.0,2,Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'); a frequently occurring elicitor-responsive cis-acting element. Regulates trichome development; production of mucilage and tannin in seed coats; and maybe root hair development.|Transcription factor involved in starch synthesis (PubMed:12953112). Acts as a transcriptional activator in sugar signaling (PubMed:16167901). Interacts specifically with the SURE and W-box elements; but not with the SP8a element (PubMed:12953112).
SUI11_ARATH,Cluster-55048.1,4,Probably involved in translation.
PRK1_ARATH,Cluster-37947.0,7,Receptor-like kinase involved in the control of pollen germination and pollen tube polar growth (PubMed:23024212).
PRK1_PETIN,Cluster-43032.0,4,Dual-specificity kinase with both serine/threonine and tyrosine kinase activities (PubMed:8038606). Required for postmeiotic development of microspores (Ref.2). Involved in embryo sac development at the late stages of megagametogenesis (Ref.3). Involved in the phosphorylation of KIP1 (PubMed:11500547).
MTP4_ORYSJ|MTPC3_ARATH,Cluster-52306.0,4,Involved in sequestration of excess metal in the cytoplasm into vacuoles to maintain metal homeostasis.|Involved in sequestration of excess metal in the cytoplasm into vacuoles to maintain metal homeostasis.
BGL44_ARATH,Cluster-47285.0,5,NA
R144B_HUMAN,Cluster-54765.0,7,E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2; thereby promoting their degradation. Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism. However; its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX; a pro-apoptotic protein; ultimately leading to protection of cell death; But; it is not an anti-apoptotic protein per se.
PUM4_ARATH,Cluster-54624.2,4,Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs. Binds the APUM-binding elements (APBEs) in the 3'-UTR mRNA sequence of CLV1; PNH; WUS and FAS2.
EPFL6_ARATH,Cluster-21948.0,2,Acts primarily as positive regulator of inflorescence growth. Endodermal expression is sufficient for proper inflorescence architecture (PubMed:22474391). Redundantly involved with EPFL4 in procambial development regulation. Acts also as tissue-specific regulator of epidermal pattern. Controls stomatal patterning by repressing stomatal production. TMM (AC Q9SSD1) functions to dampen or block CHAL signaling. Not processed by SDD1 (AC O64495). Acts as growth-regulatory ligand for ERECTA family receptors.
C90D1_ARATH,Cluster-38192.0,7,Involved in brassinosteroid (BR) biosynthesis (PubMed:15703058; PubMed:17138693). May convert teasterone to 3-dehydroteasterone; or 6-deoxoteasterone to 3-dehydro-6-deoxoteasterone (PubMed:15703058). C-23 hydroxylase that converts directly (22S;24R)-22-hydroxy-5-alpha-ergostan-3-one and 3-epi-6-deoxocathasterone to 3-dehydro-6-deoxoteasterone and 6-deoxotyphasterol; respectively (PubMed:17138693). These C-23 hydroxylation shortcuts bypass campestanol; 6-deoxocathasterone; and 6-deoxoteasterone (PubMed:17138693).
C90B1_ARATH,Cluster-51276.0,4,Catalyzes the C22-alpha-hydroxylation step in brassinosteroids biosynthesis. Converts campestanol to 6-deoxocathasterone and 6-oxocampestanol to cathasterone.
NIP1_NICAL,Cluster-2800.0,7,Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
MAVI_CUCPE,Cluster-53750.0,4,Required for innate immune defense against viruses. Acts downstream of DHX33; DDX58/RIG-I and IFIH1/MDA5; which detect intracellular dsRNA produced during viral replication; to coordinate pathways leading to the activation of NF-kappa-B; IRF3 and IRF7; and to the subsequent induction of antiviral cytokines such as IFN-beta and RANTES (CCL5). Peroxisomal and mitochondrial MAVS act sequentially to create an antiviral cellular state. Upon viral infection; peroxisomal MAVS induces the rapid interferon-independent expression of defense factors that provide short-term protection; whereas mitochondrial MAVS activates an interferon-dependent signaling pathway with delayed kinetics; which amplifies and stabilizes the antiviral response. May activate the same pathways following detection of extracellular dsRNA by TLR3. May protect cells from apoptosis.
SRS1_ARATH|SHI_ARATH,Cluster-32251.0,5,Transcription activator that binds DNA on 5'-ACTCTAC-3' and promotes auxin homeostasis-regulating gene expression (e.g. YUC genes); as well as genes affecting stamen development; cell expansion and timing of flowering. Synergistically with other SHI-related proteins; regulates gynoecium; stamen and leaf development in a dose-dependent manner; controlling apical-basal patterning. Promotes style and stigma formation; and influences vascular development during gynoecium development. May also have a role in the formation and/or maintenance of the shoot apical meristem (SAM).|Transcription activator that binds DNA on 5'-ACTCTAC-3' and promotes auxin homeostasis-regulating gene expression (e.g. YUC genes); as well as genes affecting stamen development; cell expansion and timing of flowering. Synergistically with other SHI-related proteins; regulates gynoecium; stamen and leaf development in a dose-dependent manner; controlling apical-basal patterning. Promotes style and stigma formation; and influences vascular development during gynoecium development. May also have a role in the formation and/or maintenance of the shoot apical meristem (SAM). Suppressor of the gibberellin (GA) signal transduction.
WTR13_ARATH|WTR14_ARATH,Cluster-44468.0,4,|
PTR9_ARATH|PTR11_ARATH,Cluster-45875.0,2,Endopeptidase that degrades small peptides of less than 7 kDa; such as glucagon and insulin.|
FLZ6_ARATH|FLZ5_ARATH,Cluster-56041.0,5,May act as an adapter to facilitate the interaction of SnRK1 complex with effector proteins; conferring tissue- and stimulus-type specific differences in the SnRK1 regulation pathway (PubMed:24600465). Negatively regulates KIN10 leading to a repression of the SnRK1 signaling pathway (PubMed:29406622).|May act as an adapter to facilitate the interaction of SnRK1 complex with effector proteins; conferring tissue- and stimulus-type specific differences in the SnRK1 regulation pathway.
BH091_ARATH,Cluster-44397.0,5,NA
IQD1_ARATH|IQD14_ARATH,Cluster-37054.0,4,Modulates expression of glucosinolate pathway genes. May associate with nucleic acids and regulate gene expression at the transcriptional or post-transcriptional level (PubMed:15960618; PubMed:23204523). Recruits KLCR1 and calmodulin proteins to microtubules; thus being a potential scaffold in cellular signaling and trafficking (PubMed:23204523).|
DOF17_ARATH,Cluster-50757.0,5,Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence.
MYB78_ARATH|MYB2_ORYSJ,Cluster-46243.0,5,Transcription factor involved in the negative regulation of flavonol biosynthesis. Represses the early phenylpropanoid genes; phenylalanine ammonia-lyase (PAL); cinnamate 4-hydroxylase (C4H) and 4-coumarate-CoA ligase (4CL); as well as the flavonoid-specific genes; flavonoid 3'-hydroxylase (F3'H) and dihydroflavonol 4-reductase (DFR) (PubMed:24319076). Plays a role in seed germination inhibition. Negatively regulates the expression of the abscisic acid (ABA) signaling transcription factor ABI5 in seeds (PubMed:25053018).|Transcription factor involved in abiotic stress responses. Plays a regulatory role in tolerance to salt; cold; and drought stresses. Regulates positively the expression of genes involved in proline synthesis and transport; and genes involved in reactive oxygen species (ROS) scavenging such as peroxidase; superoxide dismutase and catalase during salt stress. Transactivates stress-related genes; including LEA3; RAB16A and DREB2A during salt stress.
WRK65_ARATH|WRK35_ARATH,Cluster-38945.0,2,Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'); a frequently occurring elicitor-responsive cis-acting element.|Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'); a frequently occurring elicitor-responsive cis-acting element.
Y2608_ARATH,Cluster-43800.0,7,NA
Y5576_ARATH,Cluster-32593.0,4,NA
PNSL2_ARATH,Cluster-44547.0,2,NDH shuttles electrons from NAD(P)H:plastoquinone; via FMN and iron-sulfur (Fe-S) centers; to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation; and thus conserves the redox energy in a proton gradient (Probable). Required for both formation and activity of the chloroplast NAD(P)H dehydrogenase (NDH) complex (PubMed:20430763; PubMed:20460499).
SNP30_ARATH,Cluster-30365.0,4,Vesicle trafficking protein that functions in the secretory pathway.
PIN2_ARATH,Cluster-30434.0,5,Acts as a component of the auxin efflux carrier. Seems to be involved in the root-specific auxin transport; and mediates the root gravitropism. Its particular localization suggest a role in the translocation of auxin towards the elongation zone.
PIN1C_ORYSJ,Cluster-44852.0,6,May act as a component of the auxin efflux carrier.
SPCH_ARATH,Cluster-2206.0,5,Transcription factor acting as an integration node for stomata and brassinosteroid (BR) signaling pathways to control stomatal initiation and development (PubMed:22466366; PubMed:28507175). Activates transcription when in the presence of SCRM/ICE1 (PubMed:28507175). Functions as a dimer with SCRM or SCRM2 during stomatal initiation (PubMed:18641265). Required for the initiation; the spacing and the formation of stomata; by promoting the first asymmetric cell divisions (PubMed:25843888; PubMed:25680231; PubMed:19008449). Together with FMA and MUTE; modulates the stomata formation. Involved in the regulation of growth reduction under osmotic stress (e.g. mannitol); associated with a quick decrease of meristemoid mother cells (MMCs) number lower stomatal index and density (PubMed:25381317).
BH051_ARATH,Cluster-55174.0,1,Transcription factor that plays a positive role in salt stress tolerance. Interacts with TIFY11A/JAZ9 and binds to the promoter of some potassium ion transporter genes to regulate potassium homeostasis during salt stress.
VQ31_ARATH|CDA7L_HUMAN,Cluster-765.0,2,May modulate WRKY transcription factor activities.|Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2; but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.
CP122_ARATH,Cluster-28508.2,2,Acts as a linker essential in the assembly of a core complex of PRK/GAPDH. Coordinates the reversible inactivation of chloroplast enzymes GAPDH and PRK during darkness in photosynthetic tissues.
AKT1_ARATH,Cluster-48236.1,6,Highly selective inward-rectifying potassium channel that mediate potassium uptake by plant roots in response to low K(+) conditions; by a calcium-; CBL-; and CIPK-dependent pathway. Positively regulated by phosphorylation by CIPK23. Negatively regulated by a kinase-independent regulatory mechanism involving a competing direct binding of CBL10. Involved in the stomatal regulation by monitoring the turgor pressure in guard cells. Assuming opened or closed conformations in response to the voltage difference across the membrane; the channel is activated by hyperpolarization. May interact with the cytoskeleton or with regulatory proteins (PubMed:12678562; PubMed:16814720; PubMed:16895985; PubMed:17898163; PubMed:9572739). Is essential with POT5/HAK5 for high-affinity potassium uptake in roots during seedling establishment and postgermination growth under low potassium conditions (PubMed:20413648).
KCS2_ARATH|KCS11_ARATH,Cluster-54693.2,2,|Active on both saturated and mono-unsaturated acyl chains C16 to C20.
KCS11_ARATH,Cluster-54693.0,2,Active on both saturated and mono-unsaturated acyl chains C16 to C20.
RHA2B_ARATH,Cluster-46242.1,1,E3 ubiquitin-protein ligase involved in the positive regulation of abscisic acid (ABA) signaling and responses to salt and osmotic stresses during seed germination and early seedling development. Acts additively with RHA2A in regulating ABA signaling and drought response. Possesses E3 ubiquitin ligase activity in vitro.
PIN2_ARATH,Cluster-56100.0,4,Acts as a component of the auxin efflux carrier. Seems to be involved in the root-specific auxin transport; and mediates the root gravitropism. Its particular localization suggest a role in the translocation of auxin towards the elongation zone.
PIN2_ORYSJ,Cluster-31000.0,5,NA
PIN1C_ORYSJ|PINI_ARATH,Cluster-41687.1,5,May act as a component of the auxin efflux carrier.|Acts as a component of the auxin efflux carrier. Seems to be involved in the basipetal auxin transport. Mediates the formation of auxin gradient which is required to ensure correct organogenesis. Coordinated polar localization of PIN1 is directly regulated by the vesicle trafficking process and apical-basal PIN1 polarity also depends on the phosphorylation of conserved serine residues by PID kinase. The ARF-GEF protein GNOM is required for the correct recycling of PIN1 between the plasma membrane and endosomal compartments.
NLTP_PINTA|NLTP8_HORVU,Cluster-3083.6,3,Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.|Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
NLTP_PINTA|NLTP8_HORVU,Cluster-3083.7,2,Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.|Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
MYBP_MAIZE,Cluster-53928.2,3,NA
MYBP_MAIZE,Cluster-53928.4,3,NA
KCS10_ARATH|KCS15_ARATH,Cluster-19627.0,5,Contributes to cuticular wax and suberin biosynthesis. Prevents the postgenital fusion of epiderm cells in organs in contact; as well as ectopic pollen hydration and germination. Required during ovules formation. May regulate an epidermis-specific developmental program during gynoecial ontogeny.|
DIRL1_ARATH,Cluster-57697.0,5,Putative lipid transfer protein required for systemic acquired resistance (SAR) long distance signaling. May interact with a lipid-derived molecule to promote long distance signaling associated with SAR. Together with AZI1; required for glycerol-3-phosphate- (G3P) and azelaic acid- (AA) induced systemic acquired resistance (SAR). Component of plant systemic immunity involved in priming defenses in a AA-dependent manner; by modulating production and/or translocation of a mobile signal(s) during SAR.
BIC2_ARATH,Cluster-30484.0,4,Regulates the blue-light dependent dimerization of CRY2 and formation of photobodies. Inhibits CRY phosphorylation.
QORL2_NEMVE,Cluster-56957.0,4,NA
YL728_MIMIV,Cluster-8584.0,7,NA
GDL61_ARATH,Cluster-56291.6,4,NA
GDL61_ARATH,Cluster-56291.1,4,NA
FDL11_ARATH|FDL16_ARATH,Cluster-24959.0,5,|
RHD3_ARATH|RHD31_ARATH,Cluster-35245.0,6,Probable GTP-binding protein involved in cell wall expansion. Required for appropriate root and root hair cells enlargement. May inhibit vacuole enlargement during root hair cell expansion. Plays a role in cell wall biosynthesis and actin organization. Seems to act independently from auxin and ethylene pathways. May regulate membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER).|Probable GTP-binding protein that may be involved in cell development.
CYP38_ARATH,Cluster-57630.0,2,Required for the assembly and stabilization of PSII; but has no PPIases activity.
TF2B_ORYSJ|TF2B2_ARATH,Cluster-29999.0,5,General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II.|General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II.
EIF3C_MEDTR,Cluster-35845.0,7,Component of the eukaryotic translation initiation factor 3 (eIF-3) complex; which is involved in protein synthesis of a specialized repertoire of mRNAs and; together with other initiation factors; stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
RUP2_ARATH,Cluster-31025.0,1,Functions in association with RUP1 as repressor of UV-B-induced photomorphogenesis mediated by UVR8 and HY5. Plays a crucial negative feedback regulatory role downstream of UVR8-COP1 to inhibit UVR8 function; balance UV-B-specific responses and ensure normal plant growth. Is involved in the regulation of photoperiodic flowering and vegetative development. May act as negative regulator of photoperiodic flowering by suppressing flowering through the action of CONSTANS (CO) and FLOWERING LOCUS T (FT).
NLTP_VIGUN|NLTP2_APIGA,Cluster-29917.3,1,Potential lipid transfer protein.|Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
OFP8_ARATH,Cluster-35368.0,2,Transcriptional repressor that regulates multiple aspects of plant growth and development through the regulation of BEL1-LIKE (BLH) and KNOX TALE (KNAT) homeodomain transcription factors.
GOLS2_SOLLC,Cluster-30438.0,2,Galactinol synthase involved in the biosynthesis of raffinose family oligosaccharides (RFOs) that function as osmoprotectants. May promote plant stress tolerance.
PRB1_TOBAC,Cluster-27577.0,4,Probably involved in the defense reaction of plants against pathogens.
CCX3_ARATH,Cluster-51095.0,2,Endomembrane-localized H(+)-dependent K(+) and Na(+) transporter. May have a function associated with the pollen vacuole during tube elongation and polarized top growth.
SPSA2_CRAPL,Cluster-47979.0,4,Plays a role in photosynthetic sucrose synthesis by catalyzing the rate-limiting step of sucrose biosynthesis from UDP-glucose and fructose- 6-phosphate. Involved in the regulation of carbon partitioning in the leaves of plants. May regulate the synthesis of sucrose and therefore play a major role as a limiting factor in the export of photoassimilates out of the leaf. Plays a role for sucrose availability that is essential for plant growth and fiber elongation.
EDR2_ARATH,Cluster-38481.0,4,Negative regulator of the salicylic acid- (SA-) mediated resistance to pathogens; including the biotrophic powdery mildew pathogens Golovinomyces cichoracearum and Blumeria graminis; and the downy mildew pathogen Hyaloperonospora parasitica; probably by limiting the initiation of cell death and the establishment of the hypersensitive response (HR). Prevents ethylene-induced senescence. Binds to phosphatidylinositol-4-phosphate (PtdIns(4)P) in vitro.
UXS4_ARATH,Cluster-37492.0,2,Catalyzes the NAD-dependent decarboxylation of UDP-glucuronic acid to UDP-xylose. Necessary for the biosynthesis of the core tetrasaccharide in glycosaminoglycan biosynthesis.
WRK48_ARATH,Cluster-52500.0,4,Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'); a frequently occurring elicitor-responsive cis-acting element.
SYT2_ARATH|SYT1_ARATH,Cluster-39025.0,4,May play an important role in regulating an unconventional protein trafficking from the cytosol to the extracelluar matrix.|Plays an important role in maintaining plasma membrane integrity during freezing and osmotic stresses. May function in membrane resealing during calcium-dependent freezing tolerance. May regulate endocytosis and endosome recycling at the plasma membrane and cell-to-cell trafficking of cabbage leaf curl virus (CaLCuV) and tobacco mosaic virus (TMV) movement proteins via plasmodesmata.
DPOLA_ORYSJ|DPOLA_ARATH,Cluster-42254.3,2,Polymerase alpha in a complex with DNA primase is a replicative polymerase.|
BGLC_OLEEU|BGL11_ORYSJ,Cluster-34068.0,1,Major beta-glucosidase activating oleuropein into a potent protein cross-linking agent (PubMed:25697790; PubMed:28483880). No activity with rutin; luteolin or p-nitrophenyl-beta-glucopyranoside as substrates (PubMed:25697790).|
DOF37_ARATH|DOF46_ARATH,Cluster-40329.0,5,Transcription factor specifically involved in the maternal control of seed germination. Regulates transcription by binding to a 5'-AA[AG]G-3' consensus core sequence. May ensure the inactivity of a component that would be activated to trigger germination as a consequence of red light perception.|Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence.
PX11D_ARATH,Cluster-40511.0,2,Involved in peroxisomal proliferation. Promotes peroxisomal duplication; aggregation or elongation without fission.
RAA5A_ARATH,Cluster-25253.0,6,NA
Y1461_ARATH|Y1960_ARATH,Cluster-53589.0,6,|
NPY3_ARATH,Cluster-18587.0,5,May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). May play an essential role in auxin-mediated organogenesis and in root gravitropic responses.
NPY2_ARATH,Cluster-35717.0,5,May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). May play an essential role in auxin-mediated organogenesis and in root gravitropic responses.
BGAL_BRAOL|BGA15_ARATH,Cluster-4983.0,7,Cleaves beta-linked terminal galactosyl residues from gangliosides; glycoproteins; and glycosaminoglycans.|
CALM3_PETHY,Cluster-39710.0,4,Calmodulin mediates the control of a large number of enzymes; ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
ADHL7_ARATH,Cluster-30320.0,1,NA
PIP28_ARATH,Cluster-46016.0,5,Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
PIP21_ARATH,Cluster-49179.3,1,Water channel required to facilitate the transport of water across cell membrane. Probably involved in root water uptake. Its function is impaired by Hg(2+).
PIP21_ARATH,Cluster-49179.2,1,Water channel required to facilitate the transport of water across cell membrane. Probably involved in root water uptake. Its function is impaired by Hg(2+).
2A5B_ARATH,Cluster-55321.0,4,The B regulatory subunit may modulate substrate selectivity and catalytic activity; and also may direct the localization of the catalytic enzyme to a particular subcellular compartment (By similarity). Required for the formation of the PP2A holoenzyme that positively regulates brassinosteroid signaling by dephosphorylating and activating BZR1 (PubMed:21258370).
PILR1_FORIN,Cluster-50594.0,1,Reductase involved in lignan biosynthesis. Catalyzes the enantioselective sequential conversion of (+)-pinoresinol into (+)-lariciresinol and of (+)-lariciresinol into (-)-secoisolariciresinol. Abstracts the 4R-hydride from the NADPH cofactor during catalysis.
LBD21_ARATH,Cluster-35601.0,5,NA
EPF1_ARATH,Cluster-16562.0,5,Controls stomatal patterning. Regulates asymmetric cell division during guard cell differentiation. Mediates stomatal development inhibition. Not cleaved by the protease CRSP (AC Q9LNU1) (PubMed:25043023). MEPF1: mobile signal controlling stomatal development in a non-cell-autonomous manner (PubMed:22241782). Uses ERL1 as major receptor (PubMed:22241782). May act by competing with somatogen (AC Q9SV72) for the same receptor; TMM (AC Q9SSD1) (PubMed:22027592).
PERK4_ARATH|PERK5_ARATH,Cluster-39730.1,4,|Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
PDF1_ARATH,Cluster-618.0,5,May be involved in the regulation of meristem growth.
CFI_DIACA,Cluster-55610.0,2,Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones. Responsible for the isomerization of 4;2';4';6'-tetrahydroxychalcone (also termed chalcone) into naringenin.
SCL3_ARATH,Cluster-55325.0,4,Probable transcription factor involved in plant development.
KN14K_ORYSJ|KN14C_ORYSJ,Cluster-34574.0,7,|Kinesin that supports microtubule movement in an ATP-dependent manner and that functions as a minus-end directed motor as well as a plus-end tracking protein. During mitosis; is involved in early spindle assembly. Participates in the capture of antiparallel interpolar microtubules and helps in generating force to coalign microtubules.
HMA5_ARATH,Cluster-55292.0,4,Involved in copper import into the cell. May play a role in copper detoxification in roots.
KNOS1_ORYSJ,Cluster-45736.0,1,NA
SBT17_ARATH,Cluster-46820.0,3,NA
ROC5_NICSY,Cluster-55074.1,3,Could be involved in splicing and/or processing of chloroplast RNA's.
IDD10_ARATH,Cluster-41549.0,2,Transcription factor that; together with BIB; regulates tissue boundaries and asymmetric cell division by a rapid up-regulation of 'SCARECROW' (SCR); thus controlling the nuclear localization of 'SHORT-ROOT' (SHR) and restricting its action (PubMed:17785527; PubMed:25829440). Binds DNA via its zinc fingers (PubMed:28211915; PubMed:24821766). Recognizes and binds to SCL3 promoter sequence 5'-AGACAA-3' to promotes its expression when in complex with RGA (PubMed:24821766). Confines CYCD6 expression to the cortex-endodermis initial/daughter (CEI/CEID) tissues (PubMed:25829440). Required for radial patterning and stem cell maintenance (PubMed:17785527). Counteracted by 'MAGPIE' (MGP) (PubMed:17785527). Binds to the SCR and MGP promoter sequences (PubMed:21935722). Controls position-dependent signals that regulate epidermal-cell-type patterning (PubMed:20356954).
P2A01_ARATH,Cluster-56494.0,6,Protein phosphatase that modulates defense response to pathogenic bacteria; conferring resistance and promoting salicylic acid (SA) accumulation.
HIP6_ARATH,Cluster-54645.1,1,Heavy-metal-binding protein. Involved in the maintenance of heavy metal homeostasis and/or in detoxification.
ANK3_MOUSE|ANK2_HUMAN,Cluster-43981.0,2,Membrane-cytoskeleton linker. May participate in the maintenance/targeting of ion channels and cell adhesion molecules at the nodes of Ranvier and axonal initial segments (By similarity). In skeletal muscle; required for costamere localization of DMD and betaDAG1. Regulates KCNA1 channel activity in function of dietary Mg(2+) levels; and thereby contributes to the regulation of renal Mg(2+) reabsorption (PubMed:23903368).|Plays an essential role in the localization and membrane stabilization of ion transporters and ion channels in several cell types; including cardiomyocytes; as well as in striated muscle cells. In skeletal muscle; required for proper localization of DMD and DCTN4 and for the formation and/or stability of a special subset of microtubules associated with costameres and neuromuscular junctions. In cardiomyocytes; required for coordinate assembly of Na/Ca exchanger; SLC8A1/NCX1; Na/K ATPases ATP1A1 and ATP1A2 and inositol 1;4;5-trisphosphate (InsP3) receptors at sarcoplasmic reticulum/sarcolemma sites. Required for expression and targeting of SPTBN1 in neonatal cardiomyocytes and for the regulation of neonatal cardiomyocyte contraction rate (PubMed:12571597). In the inner segment of rod photoreceptors; required for the coordinated expression of the Na/K ATPase; Na/Ca exchanger and beta-2-spectrin (SPTBN1) (By similarity). Plays a role in endocytosis and intracellular protein transport. Associates with phosphatidylinositol 3-phosphate (PI3P)-positive organelles and binds dynactin to promote long-range motility of cells. Recruits RABGAP1L to (PI3P)-positive early endosomes; where RABGAP1L inactivates RAB22A; and promotes polarized trafficking to the leading edge of the migrating cells. Part of the ANK2/RABGAP1L complex which is required for the polarized recycling of fibronectin receptor ITGA5 ITGB1 to the plasma membrane that enables continuous directional cell migration.
CEPR1_ARATH,Cluster-43129.0,4,Receptor kinase involved in the perception of C-terminally encoded plant signaling peptide (CEP) and subsequent regulation of root and shoot development (PubMed:25324386). Required for xylem and phloem cell files morphology and organization; probably by preventing ectopic lignification in phloem cells (PubMed:21853254). Together with CEPR2; mediates systemic nitrogen (N)-demand signaling upon the perception of root-derived peptides (e.g. CEP1) via the up-regulation of genes involved in N uptake and assimilation pathways (PubMed:25324386). Regulates positively lateral root initiation and development; probably repressed by the signaling peptide CEP5 (PubMed:27296247).
LBD27_ARATH,Cluster-22290.0,7,NA
CB26_PETSP|CB23_ORYSJ,Cluster-22947.0,2,The light-harvesting complex (LHC) functions as a light receptor; it captures and delivers excitation energy to photosystems with which it is closely associated.|The light-harvesting complex (LHC) functions as a light receptor; it captures and delivers excitation energy to photosystems with which it is closely associated.
CB2B_SOLLC|CB27_TOBAC,Cluster-20264.0,2,The light-harvesting complex (LHC) functions as a light receptor; it captures and delivers excitation energy to photosystems with which it is closely associated.|
FLZ3_ARATH,Cluster-43903.0,4,May act as an adapter to facilitate the interaction of SnRK1 complex with effector proteins; conferring tissue- and stimulus-type specific differences in the SnRK1 regulation pathway.
TGA1_ARATH,Cluster-52579.0,4,Transcriptional activator that binds specifically to the DNA sequence 5'-TGACG-3'. Recognizes ocs elements like the as-1 motif of the cauliflower mosaic virus 35S promoter. Binding to the as-1-like cis elements mediate auxin- and salicylic acid-inducible transcription. May be involved in the induction of the systemic acquired resistance (SAR) via its interaction with NPR1. Could also bind to the Hex-motif (5'-TGACGTGG-3') another cis-acting element found in plant histone promoters.
KLCR1_ARATH|KIRO_ACTDE,Cluster-48830.1,2,|Plays a significant role in the normal development and function of the glomerular permeability. Signaling protein that needs the presence of TEC kinases to fully trans-activate the transcription factor AP-1.
KLCR1_ARATH,Cluster-48830.2,2,NA
KLCR1_ARATH,Cluster-48830.3,2,NA
KLCR1_ARATH|KIRO_ACTDE,Cluster-48830.6,2,|Plays a significant role in the normal development and function of the glomerular permeability. Signaling protein that needs the presence of TEC kinases to fully trans-activate the transcription factor AP-1.
KIRO_ACTDE,Cluster-48830.0,2,Plays a significant role in the normal development and function of the glomerular permeability. Signaling protein that needs the presence of TEC kinases to fully trans-activate the transcription factor AP-1.
DRP3A_ARATH,Cluster-21328.0,5,Involved in the control of mitochondrial and peroxisomal division and morphology. In association with PEX11C; PEX11D; PEX11E and FIS1B; is involved in cell cycle-associated constitutive self-replication of preexisting peroxisomes.
DSEL_ARATH,Cluster-3078.0,5,Acylhydrolase that catalyzes the hydrolysis of 1;3-diacylglycerol (1;3-DAG) and 1-monoacylglycerol (1-MAG) at the sn-1 position. High activity toward 1;3-DAG and 1-MAG; but low activity toward 1;2-diacylglycerol (1;2-DAG) and 1-lysophosphatidylcholine (1-LPC); and no activity toward phosphatidylcholine (PC); monogalactosyldiacylglycerol (MGDG); digalactosyldiacylglycerol (DGDG); triacylglycerol (TAG) and 2-monoacylglycerol (2-MAG). May be involved in the negative regulation of seedling establishment by inhibiting the breakdown; beta-oxidation and mobilization of seed storage oils.
C90C1_ARATH,Cluster-49128.0,4,Involved in brassinosteroid (BR) biosynthesis (PubMed:15703058; PubMed:17138693). Converts typhasterol to castasterone and 6-deoxotyphasterol to 6-deoxocastasterone (PubMed:15703058). C-23 hydroxylase that converts directly (22S;24R)-22-hydroxy-5-alpha-ergostan-3-one and 3-epi-6-deoxocathasterone to 3-dehydro-6-deoxoteasterone and 6-deoxotyphasterol; respectively (PubMed:17138693). These C-23 hydroxylation shortcuts bypass campestanol; 6-deoxocathasterone; and 6-deoxoteasterone (PubMed:17138693). Required for the regulation of polar elongation of leaf cells (PubMed:9694802; PubMed:10430960). Required for the longitudinal elongation of floral organs (PubMed:10430960).
GINT1_ARATH,Cluster-37020.1,5,Glycosyltransferase that mediates the glycosylation of glycosylinositol phosphorylceramides (GIPCs); the major sphingolipids in the plasma membrane; acts as a HexN(Ac)-specific GIPC sugar transferase. Responsible for the glycosylation of a subgroup of GIPCs found in seeds and pollen that contain GlcNAc and GlcN (GlcN(Ac)). Maybe involved in the maintenance of cell-cell adhesion.
GINT1_ARATH,Cluster-37020.0,4,Glycosyltransferase that mediates the glycosylation of glycosylinositol phosphorylceramides (GIPCs); the major sphingolipids in the plasma membrane; acts as a HexN(Ac)-specific GIPC sugar transferase. Responsible for the glycosylation of a subgroup of GIPCs found in seeds and pollen that contain GlcNAc and GlcN (GlcN(Ac)). Maybe involved in the maintenance of cell-cell adhesion.
PME51_ARATH,Cluster-34495.0,4,Acts in the modification of cell walls via demethylesterification of cell wall pectin.
BBX32_ARATH|COLX_ARATH,Cluster-33757.0,5,Repressor of light-mediated regulation of seedling development. Functions by suppressing the activities of positive cofactors like BBX21 and HY5 involved in modulating light-regulated gene expression and growth.|Seems to play an essential role in plague transmission by mediating flea blockage in a temperature-dependent fashion. Fibrinolytic activity prevails at 37 degrees Celsius whereas coagulase expression predominates at lower temperatures (<30 degrees Celsius). Activates plasminogen by cleaving it.
PSAO_ARATH,Cluster-22889.1,2,Involved in the balancing of excitation energy between the two photosystems I (PSI) and II (PSII).
PSAO_ARATH,Cluster-22889.0,2,Involved in the balancing of excitation energy between the two photosystems I (PSI) and II (PSII).
MYO12_ARATH,Cluster-55986.0,1,Myosin heavy chain that is required for the cell cycle-regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments; thereby transporting its cargo along polarized actin cables.
IQM1_ARATH|IQM4_ARATH,Cluster-46355.0,5,Involved in the modulation of stomatal movement. Promotes stomatal opening. May play a role in the regulation of chitin signaling. May be involved in biotic and abiotic stress responses.|May be involved in biotic and abiotic stress responses.
UBC25_ARATH,Cluster-53297.0,5,Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.
NRAM3_ORYSJ|NRAM1_ARATH,Cluster-57166.0,4,Probable metal transporter.|High affinity manganese (Mn) transporter involved in Mn acquisition from the soil. Required for Mn uptake into the root in conditions of low Mn availability. Can transport iron (Fe); cadmium (Cd) and cobalt (Co).
AB39G_ARATH|PDR2_NICPL,Cluster-35626.0,6,May be a general defense protein.|May be a general defense protein.
PDCB3_ARATH,Cluster-40177.0,5,Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding; inhibits T-cell effector functions in an antigen-specific manner. Possible cell death inducer; in association with other factors.
C7A29_PANGI,Cluster-34869.0,3,Probable heme-thiolate monooxygenase.
GPAT6_ARATH,Cluster-28612.1,4,Esterifies acyl-group from acyl-ACP to the sn-2 position of glycerol-3-phosphate; a step in cutin biosynthesis.
WDR44_BOVIN|WDR44_XENLA,Cluster-54543.0,5,Downstream effector for RAB11. May be involved in vesicle recycling.|Downstream effector for rab11. May be involved in vesicle recycling.
1433_MESCR|14334_SOLLC,Cluster-1145.0,5,|
PROCF_OLEEU,Cluster-56584.0,4,Binds to actin and affects the structure of the cytoskeleton. At high concentrations; profilin prevents the polymerization of actin; whereas it enhances it at low concentrations.
CHX18_ARATH,Cluster-49240.0,7,May operate as a cation/H(+) antiporter.
ABP20_PRUPE,Cluster-46502.0,2,Probable receptor for the plant growth-promoting hormone auxin.
DAD2_PETHY,Cluster-34831.0,1,Involved in strigolactone signaling pathway. May function downstream of strigolactone synthesis; as a component of hormone signaling or as an enzyme that participates in the conversion of strigolactones to the bioactive form. Can hydrolyze the synthetic strigolactone analog GR24 in vitro. Strigolactones are hormones that inhibit tillering and shoot branching through the MAX-dependent pathway; contribute to the regulation of shoot architectural response to phosphate-limiting conditions and function as rhizosphere signal that stimulates hyphal branching of arbuscular mycorrhizal fungi and trigger seed germination of root parasitic weeds.
TIC32_ARATH,Cluster-41075.1,4,Involved in protein precursor import into chloroplasts. Part of the redox regulon consisting of TIC32; TIC 55 and TIC62.
ACR10_ARATH,Cluster-51645.0,3,May bind amino acids.
OTU_ARATH,Cluster-57305.1,4,Essential for female fertility; germ cell division and differentiation.
FB60_ARATH,Cluster-47708.0,3,NA
LRP1_ARATH|SRS5_ARATH,Cluster-48587.0,5,Transcription activator that binds DNA on 5'-ACTCTAC-3' and promotes auxin homeostasis-regulating gene expression (e.g. YUC genes); as well as genes affecting stamen development; cell expansion and timing of flowering. Synergistically with other SHI-related proteins; regulates gynoecium; stamen and leaf development in a dose-dependent manner; controlling apical-basal patterning. Promotes style and stigma formation; and influence vascular development during gynoecium development. May also have a role in the formation and/or maintenance of the shoot apical meristem (SAM). Modulates root growth.|Transcription activator that binds DNA on 5'-ACTCTAC-3' and promotes auxin homeostasis-regulating gene expression (e.g. YUC genes); as well as genes affecting stamen development; cell expansion and timing of flowering. Synergistically with other SHI-related proteins; regulates gynoecium; stamen and leaf development in a dose-dependent manner; controlling apical-basal patterning. Promotes style and stigma formation; and influences vascular development during gynoecium development. May also have a role in the formation and/or maintenance of the shoot apical meristem (SAM).
PI5K9_ARATH,Cluster-43630.1,1,NA
FH11_ARATH,Cluster-46054.0,5,NA
STP8_ARATH|MST4_ORYSJ,Cluster-53125.0,4,Mediates an active uptake of hexoses; probably by sugar/hydrogen symport.|
ASPA_ARATH,Cluster-50498.0,1,NA
GRXC6_ARATH,Cluster-33837.0,4,Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
TCP22_ARATH|TCP8_ARATH,Cluster-34496.1,2,Plays a pivotal role in the control of morphogenesis of shoot organs by negatively regulating the expression of boundary-specific genes such as CUC genes; probably through the induction of miRNA (e.g. miR164). In association with ABAP1; exerts a negative role in cell proliferation in leaves; possibly by inhibiting mitotic DNA replication. Participates in ovule develpment (PubMed:25378179).|
MB101_ARATH|MYB97_ARATH,Cluster-48341.0,5,Transcription activator (PubMed:24278028; PubMed:25268707). Binds to 5'-CAACTGTC-3' and/or 5'-TAACAAA-3' motif in target gene promoter (e.g. alpha-amylase) to promote their expression (PubMed:11743113). Positive regulator of abscisic acid (ABA) responses leading to growth arrest during seed germination (PubMed:17217461). Promotes the expression of aleurone-related genes (e.g. CP1; CP; GASA1; BXL1 and BXL2) in seeds. Together with MYB33 and MYB65; promotes the programmed cell death (PCD) leading to vacuolation of protein storage vacuoles (PSVs) in the aleurone layers during seed germination (PubMed:20699403). Maybe involved in the regulation of leaves lamina morphogenesis (PubMed:25268707). Involved in pollen grain development (PubMed:22101548). Together with MYB97 and MYB120; functions as a male factor that controls pollen tube-synergid interaction in fertilization. Required for pollen tube growth arrest and sperm cell release in the female gametophyte; probably via the regulation of pollen tube-specific gene expression (PubMed:24278028; PubMed:23791732).|Transcription activator (PubMed:24278028). Binds to 5'-CAACTGTC-3' and/or 5'-TAACAAA-3' motif in target gene promoter to promote their expression (By similarity). Together with MYB101 and MYB120; functions as a male factor that controls pollen tube-synergid interaction in fertilization. Required for pollen tube growth arrest and sperm cell release in the female gametophyte; probably via the regulation of pollen tube-specific gene expression (PubMed:24278028; PubMed:23791732).
FMDA_METME,Cluster-43462.0,5,Hydrolyzes formamide with the production of ammonia which can be used as a source of nitrogen for growth. Also acts; more slowly; on acetamide; propanamide and butanamide.
COL10_ARATH,Cluster-53276.0,4,Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment.
STP8_ARATH|STP6_ARATH,Cluster-2880.0,5,Mediates an active uptake of hexoses; probably by sugar/hydrogen symport.|Mediates an active uptake of hexoses; probably by sugar/hydrogen symport. Can transport glucose; 3-O-methylglucose; mannose; fructose and galactose; and; to a lower extent; xylose and ribulose.
PUB35_ARATH,Cluster-56786.0,1,Functions as an E3 ubiquitin ligase.
PUB52_ARATH,Cluster-42306.0,1,Functions as an E3 ubiquitin ligase.
LAZY1_ARATH,Cluster-51221.0,5,NA
PABP7_ARATH|CHUP1_ARATH,Cluster-29213.0,6,Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis; stability and translation.|Required for the positioning and movement of chloroplasts. Interacts with profilin and actin independent of its polymerization status. Regulates chloroplast localization by anchoring chloroplasts to the plasma membrane and forming a bridge to the actin cytoskeleton.
CRR7_ARATH,Cluster-19413.1,2,Required for both formation and activity of the chloroplast NAD(P)H dehydrogenase (NDH) complex of the photosynthetic electron transport chain. May function in assembly or stabilization of the NDH complex (PubMed:16359395; PubMed:20444231). Required for the accumulation of NDH subcomplex A; which is a core part of NDH. May be involved in post-translational steps during the biogenesis of subcomplex A (PubMed:20444231).
FADX_VERFO,Cluster-56382.0,6,Converts linoleic acid to alpha-eleostearic acid (18:3(9Z;11E;13E)) and alpha-linolenic acid to alpha-parinaric acid (18:4(9Z;11E;13E;15Z)). Converts a single cis double bond at carbon 12 to two conjugated trans bonds at positions 11 and 13. Can also act as a 12(E) desaturase when acting on the monounsaturated fatty acids oleate and palmitoleate; stereoselectively introducing a trans double bond.
5GT_VERHY,Cluster-32510.0,3,Catalyzes the glucosylation at the O-5 position of anthocyanidin 3-glucosides to form anthocyanidin 3;5-di-O-glucosides using UDP-glucose as sugar donor. Anthocyanidin 3;5-di-O-glucosides are molecules that are responsible for pigmentation. Also acts on anthocyanidin 3-O-(6-O-malonylglucoside). Much less active with hydroxycinnamoylglucose derivatives. No activity in the absence of the 3-O-glucoside group.
VESTR_MEDSA,Cluster-2916.0,5,Stereospecific enzyme that catalyzes the NADPH-dependent reduction of (3R)-vestitone to (3R;4R)-4'-methoxyisoflavan-2';4;7-triol (DMI). Has no activity with (3S)-vestitone. Catalyzes the penultimate step in the biosynthesis of the phytoalexin medicarpin; and thereby contributes to plant defense reactions.
BRXL4_ARATH|BRXL2_ARATH,Cluster-43662.0,4,|
PUM7_ARATH|PUM8_ARATH,Cluster-39388.0,6,Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs.|Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs.
UGT9_GARJA,Cluster-46265.0,4,Glucosyltransferase catalyzing the beta 1-6 glucosylation of the sugar moiety of crocetin glucosyl esters to produce crocetin gentiobiosyl esters. Weak activity toward curcumin glucosides; but no activity with flavonoid glucosides; coumarin glucosides; 4-nitrophenyl glucoside or crocetin. Involved with UGT75L6 in sequential glycosylation of crocetin to crocin (bis(beta-D-gentiobiosyl) crocetin).
PRE6_ARATH,Cluster-37324.1,1,Atypical and probable non DNA-binding bHLH transcription factor that regulates light-mediated responses in day light conditions by binding and inhibiting the activity of the bHLH transcription factor HFR1; a critical regulator of light signaling and shade avoidance. Forms non-functional heterodimers with HFR1; causing liberation and activation of PIF4 from the transcriptionally inactive HFR1-PIF4 complex.
CBBY_ARATH,Cluster-44050.0,2,NA
GUN4C_ARATH,Cluster-52796.0,2,NA
ASPG2_ARATH,Cluster-34233.0,5,NA
TLPH_ORYSJ,Cluster-49119.0,7,NA
REN1_ARATH,Cluster-42148.0,4,Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Maintains the global inactivation of ARAC11/ROP1 at the apex in pollen tubes in order to regulate the polar cell growth.
AP21_ORYSI|AP23_ORYSJ,Cluster-49018.0,2,Probable transcription factor (By similarity). Involved in spikelet transition. Regulator of starch biosynthesis especially during seed development (e.g. endosperm starch granules); represses the expression of type I starch synthesis genes. Prevents lemma and palea elongation as well as grain growth.|Probable transcription factor (By similarity). Involved in spikelet transition (Probable). Together with IDS1; controls synergistically inflorescence architecture and floral meristem establishment via the regulation of spatio-temporal expression of B- and E-function floral organ identity genes in the lodicules and of spikelet meristem genes (PubMed:22003982). Prevents lemma and palea elongation as well as grain growth (PubMed:28066457). Regulates the transition from spikelet meristem to floral meristem; spikelet meristem determinancy and the floral organ development (PubMed:17144896).
4CGT_ANTMA,Cluster-28922.0,5,Glycosyltransferase involved in the biosynthesis of aurones; plant flavonoids that provide yellow coloration to flowers.
4CGT_ANTMA,Cluster-36083.17,1,Glycosyltransferase involved in the biosynthesis of aurones; plant flavonoids that provide yellow coloration to flowers.
4CGT_ANTMA,Cluster-36083.2,1,Glycosyltransferase involved in the biosynthesis of aurones; plant flavonoids that provide yellow coloration to flowers.
DREB3_ARATH,Cluster-53734.0,4,Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways.
DREB3_ARATH,Cluster-28903.0,2,Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways.
PIN6_ARATH,Cluster-55215.4,5,Component of the intracellular auxin-transport pathway (PubMed:19506555). Regulates auxin transport and auxin homeostasis (PubMed:23922907). Directly involved in the regulation of nectar production (PubMed:23551385). Involved in unfolded protein response (UPR) activation (PubMed:24180465). Involved in the control of vein patterning (PubMed:23437008; PubMed:24304505). Redundantly with PIN8; inhibits the vein-formation-promoting functions of PIN5 (PubMed:26560462). PIN5; PIN6; and PIN8 control vein network geometry; but they are expressed in mutually exclusive domains of leaf vascular cells (PubMed:26560462).
UNC13_ARATH,Cluster-32173.0,4,NA
SWT7B_ORYSI,Cluster-5250.0,5,Mediates both low-affinity uptake and efflux of sugar across the plasma membrane.
CAR4_ARATH|CAR3_ARATH,Cluster-46099.0,1,Mediates the transient calcium-dependent interaction of PYR/PYL/RCAR abscisic acid (ABA) receptors with the plasma membrane and thus regulates ABA sensitivity (PubMed:26719420; PubMed:25465408). Stimulates the GTPase/ATPase activities of YchF1; and regulates its subcellular localization. Promotes tolerance towards salinity stress by limiting the accumulation of reactive oxygen species (ROS) (PubMed:23550829). Promotes resistance to bacterial pathogens (e.g. Xanthomonas oryzae pv. oryzae and P. syringae pv. tomato DC3000) (By similarity). Binds liposomes in the absence of exogenous Ca(2+); but this activity is enhanced in the presence of Ca(2+) and generates membrane curvature (PubMed:26719420).|Stimulates the GTPase/ATPase activities of Obg-like ATPases (By similarity). Mediates the transient calcium-dependent interaction of PYR/PYL/RCAR abscisic acid (ABA) receptors with the plasma membrane and thus regulates ABA sensitivity.
PGLR_VITVI,Cluster-35287.0,4,Dual specificity glycosyltransferase that catalyzes the transfer of glucose and xylose from UDP-glucose and UDP-xylose; respectively; to a serine residue found in the consensus sequence of C-X-S-X-P-C. Specifically targets extracellular EGF repeats of protein such as CRB2; F7; F9 and NOTCH2 (By similarity). Acts as a positive regulator of Notch signaling by mediating O-glucosylation of Notch; leading to regulate muscle development (By similarity). Notch glucosylation does not affect Notch ligand binding (By similarity). Required during early development to promote gastrulation: acts by mediating O-glucosylation of CRB2; which is required for CRB2 localization to the cell membrane.
C94A1_VICSA|C94A2_VICSA,Cluster-28503.1,5,Catalyzes the omega-hydroxylation of various fatty acids (FA) from 10 to 18 carbon atoms. The substrate specificity is higher for laurate > palmitate > myristate > linolenate > linoleate > oleate > caprate. May play a minor role in cutin synthesis and could be involved in plant defense.|Catalyzes the omega-hydroxylation of various fatty acids (FA). The substrate specificity is higher for myristate > laurate = palmitate (C14>C16=C12).
ERG3_ORYSJ,Cluster-35659.0,4,NA
PP330_ARATH,Cluster-56710.1,5,NA
NLTP_LACSA|NLTP1_HORVU,Cluster-29557.0,5,Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.|Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
OPT6_ARATH,Cluster-30637.0,5,Involved in the translocation of tetra- and pentapeptides across the cellular membrane in an energy-dependent manner. Also involved in transport of glutathione derivatives and metal complexes; and may be involved in stress resistance.
COL1_ARATH,Cluster-38654.0,5,Putative transcription factor that may be involved in the light input to the circadian clock but does not affect flowering time.
LHT1_ARATH,Cluster-57505.0,7,Amino acid-proton symporter. Transporter with a broad specificity for histidine; lysine; glutamic acid; alanine; serine; proline and glycine. Involved in both apoplastic transport of amino acids in leaves and their uptake by roots.
LHT1_ARATH,Cluster-23382.0,7,Amino acid-proton symporter. Transporter with a broad specificity for histidine; lysine; glutamic acid; alanine; serine; proline and glycine. Involved in both apoplastic transport of amino acids in leaves and their uptake by roots.
CDPKW_ARATH,Cluster-27665.0,4,May play a role in signal transduction pathways that involve calcium as a second messenger. Involved in maintaining Ca2+ homeostasis in pollen tube tips by regulating CNGC18 (PubMed:24121288). Functions as regulator of the calcium-mediated abscisic acid (ABA) signaling pathway (PubMed:16299177). Phosphorylates ABA-responsive transcription factor ABF4 in vitro (PubMed:16299177).
LEA1_CICAR,Cluster-42920.0,4,Plays a positive role in the effector-triggered immunity (ETI) response (PubMed:19199050; PubMed:24006883). Involved in salicylic acid (SA)-mediated processes occurring in ETI response; but is not involved in the autophagy process (PubMed:24006883). Promotes systemic rather than local immunity (PubMed:24755512). Essential for systemic acquired resistance (SAR); but not necessary for immune signaling downstream of SA (PubMed:24755512). May act in parallel with SA (PubMed:24755512).
LEA1_CICAR,Cluster-29634.0,7,Plays a positive role in the effector-triggered immunity (ETI) response (PubMed:19199050; PubMed:24006883). Involved in salicylic acid (SA)-mediated processes occurring in ETI response; but is not involved in the autophagy process (PubMed:24006883). Promotes systemic rather than local immunity (PubMed:24755512). Essential for systemic acquired resistance (SAR); but not necessary for immune signaling downstream of SA (PubMed:24755512). May act in parallel with SA (PubMed:24755512).
CSPL1_PANGI|CSPL8_SOYBN,Cluster-16830.1,6,|
PSAF_FLATR|PSAF_SPIOL,Cluster-9042.0,2,Probably participates in efficiency of electron transfer from plastocyanin to P700 (or cytochrome c553 in algae and cyanobacteria). This plastocyanin-docking protein contributes to the specific association of plastocyanin to PSI.|Probably participates in efficiency of electron transfer from plastocyanin to P700 (or cytochrome c553 in algae and cyanobacteria). This plastocyanin-docking protein contributes to the specific association of plastocyanin to PSI.
DNJ20_ARATH,Cluster-34782.0,1,Have a continuous role in plant development probably in the structural organization of compartments.
GP107_MOUSE|GP108_HUMAN,Cluster-2741.5,5,Involved in Golgi-to-ER retrograde transport.|
ASPGB_ARATH,Cluster-29707.0,6,Acts in asparagine catabolism and also in the final steps of protein degradation via hydrolysis of a range of isoaspartyl dipeptides.
UCC1_ARATH|ENL2_ARATH,Cluster-49366.2,2,Catalyzes the hydrolysis of unsaturated hyaluronate and chondroitin disaccharides. Also degrades unsaturated heparin disaccharides. Releases 4-deoxy-4;5-didehydro D-glucuronic acid or 4-deoxy-4;5-didehydro L-iduronic acid from chondroitin disaccharides; hyaluronan disaccharides and heparin disaccharides and cleaves both glycosidic (1->3) and (1->4) bonds. Prefers sulfated glycosaminoglycans compared to unsulfated glycosaminoglycans. Probably required for mammalian cells invasion through the degradation of extracellular sulfated glycosaminoglycans such as chondroitin and hyaluronan.|
HTH_ARATH,Cluster-57681.0,5,Probable FAD-dependent enzyme. Involved in regulating post-genital organ fusion. Required to limit cellular interactions between contacting epidermal cells during floral development.
MY113_ARATH,Cluster-39915.0,3,Transcription activator; when associated with BHLH002/EGL3/MYC146; BHLH012/MYC1; or BHLH042/TT8.
LHW_ARATH,Cluster-50000.0,5,Transcription activator that regulates root development; promotes the production of stele cells in roots. Coordinately controls the number of all vascular cell types by regulating the size of the pool of cells from which they arise.
KNAT6_ARATH,Cluster-36835.0,4,NA
KNAT6_ARATH,Cluster-36835.2,6,NA
LOR15_ARATH,Cluster-56748.0,4,Might be related to the phospholipid scramblase and tubby-like superfamily of membrane tethered transcription factors.
AAP3_ARATH,Cluster-57082.0,4,NA
G3OX_PEA,Cluster-8078.0,5,Converts the inactive gibbberellin (GA) precursors GA9 and GA20 in the bioactives gibberellins GA4 and GA1. Has a small activity on GA29; producing GA8. Unable to convert GA20 to GA5; GA5 to GA3 or GA12 to GA14. Involved in the production of bioactive GA for vegetative growth and development; but not for the 3-beta-hydroxylation of GA in developing seeds.
RGP1_ORYSJ|RGP1_ARATH,Cluster-46730.0,4,UDP-L-arabinose mutase involved in the biosynthesis of cell wall non-cellulosic polysaccharides. Catalyzes the interconvertion of UDP-L-arabinopyranose (UDP-Arap) and UDP-L-arabinofuranose (UDP-Araf). Preferentially catalyzes the formation of UDP-Arap from UDP-Araf. At thermodynamic equilibrium in vitro the ratio of the pyranose form over the furanose form is 90:10. Is probably active as heteromer in vivo.|UDP-L-arabinose mutase involved in the biosynthesis of cell wall non-cellulosic polysaccharides. Catalyzes the interconvertion of UDP-L-arabinopyranose (UDP-Arap) and UDP-L-arabinofuranose (UDP-Araf) in vitro. Preferentially catalyzes the formation of UDP-Arap from UDP-Araf. At thermodynamic equilibrium in vitro the ratio of the pyranose form over the furanose form is 95:5. Is not active on other UDP-sugars (UDP-Gal; UDP-Xyl; UDP-Glc; GDP-Man and GDP-Fuc) (PubMed:21478444). Functions redundantly with RGP2 and is essential for proper cell walls and pollen development. Probably involved in the formation of the pectocellulosic cell wall layer intine. Is probably active as heteromer in vivo (PubMed:17071651).
RGP1_PEA,Cluster-49883.0,4,Probable UDP-L-arabinose mutase involved in the biosynthesis of cell wall non-cellulosic polysaccharides (By similarity). Was initially shown to possess an autoglycosylating activity which is dependent on the presence of UDP-glucose and manganese (PubMed:9207152).
GALS3_ARATH|GALS2_ARATH,Cluster-40621.0,4,Involved in the biosynthesis of beta-1;4-galactan. Beta-1;4-galactans are abundant polysaccharides in plant cell walls and are found as side-chain of rhamnogalacturonan I; which is a major component of pectin.|Involved in the biosynthesis of beta-1;4-galactan. Beta-1;4-galactans are abundant polysaccharides in plant cell walls and are found as side-chain of rhamnogalacturonan I; which is a major component of pectin.
M3K17_ARATH,Cluster-34838.0,4,Component of the abscisic acid (ABA) signaling pathway that may act as ABA signal transducer in the context of abiotic stresses. Triggers MPK7 activation in a MKK3-dependent manner. Mediates the ABA-dependent activation of the MKK3-MPK7 module.
TBL25_ARATH,Cluster-50261.0,4,May be involved in the O-acetylation of mannan (PubMed:22086088). May act as a bridging protein that binds pectin and other cell wall polysaccharides. Probably involved in maintaining esterification of pectins.
GDL44_ARATH,Cluster-31196.0,4,NA
DNJ20_ARATH,Cluster-54594.0,2,Have a continuous role in plant development probably in the structural organization of compartments.
PIRL3_ARATH,Cluster-35029.0,6,Leucine-rich repeat protein that likely mediates protein interactions; possibly in the context of signal transduction.
P2C43_ORYSJ,Cluster-31661.0,2,NA
RABEK_HUMAN|RABEK_BOVIN,Cluster-53459.0,7,|Rab9 effector required for endosome to trans-Golgi network (TGN) transport.
PDI22_ORYSJ,Cluster-49127.1,4,Acts as a protein-folding catalyst that interacts with nascent polypeptides to catalyze the formation; isomerization; and reduction or oxidation of disulfide bonds. May play a role in storage protein biogenesis.
NRAM5_ORYSJ,Cluster-35479.0,5,Probable metal transporter.
P4KG1_ARATH,Cluster-38706.0,4,The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4;5-bisphosphate (PIP2); a precursor of the second messenger inositol 1;4;5-trisphosphate (InsP3).
IRX10_ARATH,Cluster-56195.0,4,Involved in the synthesis of the hemicellulose glucuronoxylan; a major component of secondary cell walls. Probably involved in the elongation of glucuronoxylan xylosyl backbone; especially in the formation of GlcUA side chain of xylans.
Y4345_ARATH,Cluster-47388.0,3,NA
GASA6_ARATH|GASA4_ARATH,Cluster-57485.0,4,Gibberellin-regulated protein that may function in hormonal controlled steps of development such as seed germination; flowering and seed maturation.|Gibberellin-regulated protein involved in the regulation of floral meristem and floral organ identity; and promotion of seed size and weight. May play a role in the promotion of gibberellin responses such as regulation of flowering under short-day conditions; seed germination and inhibition of gibberellin oxidase. Possesses redox activity in E.coli and may function in redox regulation in planta.
GASA6_ARATH,Cluster-57485.1,6,Gibberellin-regulated protein that may function in hormonal controlled steps of development such as seed germination; flowering and seed maturation.
DFRA_ANTMA,Cluster-57035.0,1,Bifunctional enzyme involved in flavonoid metabolism.
CML46_ARATH,Cluster-26881.0,5,Potential calcium sensor.
MYBP_MAIZE,Cluster-53928.1,2,NA
EXOL2_ARATH,Cluster-40398.7,6,May play a role in a brassinosteroid-dependent regulation of growth and development.
BH030_ARATH,Cluster-47322.1,5,NA
NLTP3_ARATH,Cluster-36060.0,4,Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
CAHC_SPIOL|CAHC_TOBAC,Cluster-52276.0,4,Reversible hydration of carbon dioxide.|Reversible hydration of carbon dioxide.
GALE2_CYATE,Cluster-40981.0,5,NA
JAL3_ARATH,Cluster-33043.0,4,NA
C71A1_PERAE|C76C4_ARATH,Cluster-34818.0,5,Involved in the metabolism of compounds associated with the development of flavor in the ripening fruit process; possibly by acting as trans-cinnamic acid 4-hydrolase.|
PME34_ARATH,Cluster-47249.0,4,Acts in the modification of cell walls via demethylesterification of cell wall pectin.
CER1_ARATH|GLO15_ORYSI,Cluster-21091.4,4,|Aldehyde decarbonylase involved in the conversion of aldehydes to alkanes. Core component of a very-long-chain alkane synthesis complex.
COPA1_ARATH,Cluster-45253.3,4,The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles; which further mediate biosynthetic protein transport from the ER; via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes; and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
PNAE_RAUSE,Cluster-42679.0,1,NA
WAK3_ARATH,Cluster-55664.0,6,Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component. Binding to pectin may have significance in the control of cell expansion; morphogenesis and development.
GDL15_ARATH|GDL82_ARATH,Cluster-37259.0,5,Involved in the control of the PYK10 complex size and possibly substrate specificity. May be exported from the endoplamic reticulum upon interaction with MVP1.|
NIP11_ORYSJ,Cluster-38185.0,1,Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
NAC83_ARATH,Cluster-42432.0,4,Transcriptional repressor that negatively regulates the expression of genes involved in xylem vessel formation. Represses the transcriptional activation activity of NAC030/VND7; which regulates protoxylem vessel differentiation by promoting immature xylem vessel-specific genes expression (PubMed:20388856). Transcriptional activator that regulates the COLD-REGULATED (COR15A and COR15B) and RESPONSIVE TO DEHYDRATION (LTI78/RD29A and LTI65/RD29B) genes by binding directly to their promoters. Mediates signaling crosstalk between salt stress response and leaf aging process (PubMed:21673078). May play a role in DNA replication of mungbean yellow mosaic virus (PubMed:24442717).
PRP8A_ARATH,Cluster-1894.0,2,Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs. Required for the assembly of the U4/U6-U5 tri-snRNP complex (By similarity). Required for embryo development (Ref.3). Required for splicing efficiency of COOLAIR introns and usage of the proximal poly(A) site. COOLAIR is a set of long non-coding antisense transcripts produced at the FLOWERING LOCUS C (FLC). COOLAIR initiates just downstream of the major sense transcript poly(A) site and terminates either early or extends into the FLC promoter region. Splicing of COOLAIR by PRP8A is functionally important for FLC regulation (PubMed:24725596).
PIP12_ARATH|PIP15_ARATH,Cluster-36657.4,4,Water channel required to facilitate the transport of water across cell membrane. Essential for the water permeability of the plasma membrane and for the morphology of the root system. Its function is impaired by Hg(2+). Inhibited by cytosolic acidosis which occurs during anoxia in roots.|Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
ATB51_ARATH,Cluster-25337.0,5,Putative transcription factor.
DRMH4_ARATH,Cluster-43906.0,4,NA
MYB06_ANTMA,Cluster-36005.0,1,Transcription factor.
MLO5_ARATH,Cluster-34655.0,4,May be involved in modulation of pathogen defense and leaf cell death. Activity seems to be regulated by Ca(2+)-dependent calmodulin binding and seems not to require heterotrimeric G proteins.
AHL20_ARATH,Cluster-22677.0,2,Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs) (By similarity). Negatively regulates plant innate immunity (PTI) to pathogens through the down-regulation of the PAMP-triggered NHO1 and FRK1 expression (PubMed:20738724).
TIP13_ARATH,Cluster-28679.0,4,Potential aquaporin; which may facilitate the transport of water and small neutral solutes across cell membranes.
EC14_ARATH,Cluster-38643.0,7,Involved in the regulation of gamete interactions during the double fertilization and to prevent multiple-pollen tube attraction; mediates the redistribution of the gamete fusogen HAP2/GCS1 to the cell surface after secretion upon sperm arrival.
SCP40_ARATH,Cluster-33261.0,6,Probable carboxypeptidase.
VINSY_RAUSE|BAHD1_ARATH,Cluster-39837.0,4,Acetyltransferase that catalyzes the formation of vinorine; a precursor of the antiarrhythmic monoterpenoid indole alkaloid ajmaline. Acts on gardneral; but not on polyneuridine aldehyde or N-methylgardneral.|
PROD2_ARATH,Cluster-35306.0,4,Converts proline to delta-1-pyrroline-5-carboxylate.
Y3351_ARATH,Cluster-8157.0,7,NA
SUT34_ARATH,Cluster-57164.0,6,H(+)/sulfate cotransporter that may play a role in the regulation of sulfate assimilation.
AHL29_ARATH,Cluster-32477.0,2,Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs) (By similarity). Acts redundantly with AHL18; AHL22 and AHL27 in the regulation of flowering and regulation of the hypocotyl elongation (PubMed:19517252). Acts redundantly with AHL27/ESC to modulate hypocotyl growth inhibition in response to light (PubMed:18088311).
CIP7_ARATH,Cluster-47625.0,1,Exhibits transcriptional activation activity. Positive regulator of light-regulated genes; probably being a direct downstream target of COP1 for mediating light control of gene expression.
STC_RICCO|STP1_ARATH,Cluster-4262.0,5,Involved in modulation of glucose-regulated gene expression. Together with MTH1; represses the hexose transporter (HXT) genes in conditions of low glucose. Stimulates the SNF1 kinase by an interaction with the catalytic domain that antagonizes autoinhibition and promotes an active conformation of the kinase.|Major hexose transporter. Mediates an active uptake of hexoses; by sugar/hydrogen symport. Can transport glucose; 3-O-methylglucose; fructose; xylose; mannose; galactose; fucose; 2-deoxyglucose and arabinose. Confers sensitivity to galactose in seedlings.
JGB_ARATH,Cluster-24553.0,5,Negative regulator of pollen germination (PubMed:27468890). Prevents pollination in moist environments by inhibiting jasmonic acid synthesis (PubMed:27468890). Stabilizes pollen tube growth (PubMed:27468890).
DTX35_ARATH,Cluster-5439.4,2,NA
DTX34_ARATH|DTX20_ARATH,Cluster-5439.3,2,|Dual specificity phosphatase able to dephosphorylate phosphotyrosine; phosphoserine and phosphothreonine residues; with a preference for phosphotyrosine as a substrate.
HPSE2_ARATH,Cluster-41245.0,5,Endoglycosidase which is a cell surface and extracellular matrix-degrading enzyme. Cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans.
PLY12_ARATH,Cluster-24157.0,4,NA
AS1_ANTMA,Cluster-25354.2,1,Involved in the biosynthesis of aurones; plant flavonoids that provide yellow coloration to flowers. Can use tetrahydroxychalcone (THC); pentahydroxychalcone (PHC); THC 4'-glucoside and PHC 4'-glucoside as substrates; but not 2'-hydroxychalcone; 4-hydroxychalcone; PHC 3-glucoside; 2';6'-dihydroxy-4;4'-dimethoxychalcone; naringenin; eriodictyol and 4;4';6-trihydroxyaurone. Can also produce bracteatin from PHC.
RAC2A_ARATH,Cluster-56692.0,4,Intracellular vesicle trafficking and protein transport.
CSPLC_POPTR,Cluster-52182.0,4,NA
TKPR1_ARATH,Cluster-31030.1,4,Involved in the biosynthesis of hydroxylated tetraketide compounds that serve as sporopollenin precursors (the main constituents of exine). Is essential for pollen wall development. Acts on tetraketide alpha-pyrones and reduces the carbonyl function on the tetraketide alkyl chain to a secondary alcohol function.
FER1_SOLLC,Cluster-36815.1,2,Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
JGB_ARATH,Cluster-7185.0,2,Negative regulator of pollen germination (PubMed:27468890). Prevents pollination in moist environments by inhibiting jasmonic acid synthesis (PubMed:27468890). Stabilizes pollen tube growth (PubMed:27468890).
SWT6B_ORYSJ|SWET7_ARATH,Cluster-4294.0,5,Mediates both low-affinity uptake and efflux of sugar across the plasma membrane.|Mediates both low-affinity uptake and efflux of sugar across the plasma membrane.
TMVRN_NICGU|TAO1_ARATH,Cluster-20543.0,3,Disease resistance protein. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via a direct or indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response; which restricts the pathogen growth.|TIR-NB-LRR receptor-like protein that contributes to disease resistance induced by the Pseudomonas syringae type III effector AvrB. Acts additively with RPM1 to generate a full disease resistance response to P.syringae expressing this type III effector.
C71A9_SOYBN,Cluster-49412.13,1,NA
C71A9_SOYBN,Cluster-49412.9,3,NA
LAT52_SOLLC,Cluster-30658.0,4,May play a role during germination or early tube growth.
PST2_PETHY,Cluster-35323.0,2,May be a component of the oxygen-evolving complex.
AATP9_ARATH,Cluster-29462.0,4,Has aromatic amino acid transaminase activity.
CEPR2_ARATH,Cluster-46479.0,1,Receptor kinase involved in the perception of C-terminally encoded plant signaling peptide (CEP) and subsequent regulation of root and shoot development. Together with CEPR1; mediates systemic nitrogen (N)-demand signaling upon the perception of root-derived peptides (e.g. CEP1) via the up-regulation of genes involved in N uptake and assimilation pathways.
XERIC_ARATH,Cluster-41055.0,5,Function on abscisic acid homeostasis at post-translational level; probably through ubiquitin/proteasome-dependent substrate-specific degradation.
GH310_ARATH,Cluster-42567.0,1,Catalyzes the synthesis of indole-3-acetic acid (IAA)-amino acid conjugates; providing a mechanism for the plant to cope with the presence of excess auxin (By similarity). Involved in red light-specific hypocotyl elongation. May act downstream of a red light signal transduction and determine the degree of hypocotyl elongation (PubMed:14581632).
TIL_ARATH,Cluster-37545.0,2,Involved in basal (BT) and acquired thermotolerance (AT); probably by preventing plasma membrane lipids peroxidation induced by severe heat-shock (HS) (PubMed:19302169; PubMed:23837879). Lipocalin that confers protection against oxidative stress caused by heat; freezing; paraquat and light (PubMed:18671872; PubMed:19302169). Confers resistance to high salt (NaCl) levels; probably by protecting chloroplasts from ion toxicity via ion homeostasis maintenance (PubMed:20959419; PubMed:24028869). Required for seed longevity by insuring polyunsaturated lipids integrity (PubMed:23837879).
CANB1_NAEGR,Cluster-51797.0,1,Regulatory subunit of calcineurin; a calcium-dependent; calmodulin stimulated protein phosphatase. Confers calcium sensitivity.
CAHC_TOBAC|BCA4_ARATH,Cluster-27314.0,2,Reversible hydration of carbon dioxide.|Reversible hydration of carbon dioxide. Together with BCA1; involved in the CO(2) signaling pathway which controls gas-exchange between plants and the atmosphere by modulating stomatal development and movements. Promotes water use efficiency.
LIN1_LOTJA|LIN_MEDTR,Cluster-55118.0,4,Putative E3 ubiquitin-protein ligase involved in the rhizobial infection process. Plays an important role in the early steps of infection thread formation and in growth and differentiation of nodules.|Putative E3 ubiquitin ligase involved in the rhizobial infection process. Plays an important role in the early steps of infection thread formation and in growth and differentiation of nodules.
BAD1_ARATH|Y5262_ARATH,Cluster-44922.0,5,Involved in plant defense. Required for basal resistance against Pseudomonas syringae pv. tomato DC3000. Required for resistance against nonpathogenic bacteria. May be involved in signaling components that function downstream of SNC2 and upstream of NPR1 and WRKY70 to regulate defense responses.|
TCP2_ARATH,Cluster-50976.1,6,NA
HMDH2_GOSHI,Cluster-54298.0,6,Catalyzes the synthesis of mevalonate. The specific precursor of all isoprenoid compounds present in plants.
NAC22_ARATH,Cluster-30023.0,3,Transcriptional activator that mediates auxin signaling to promote lateral root development. Activates the expression of two downstream auxin-responsive genes; DBP and AIR3.
ADS3_ARATH,Cluster-5155.3,4,NA
ADS3_ARATH,Cluster-5155.2,6,NA
ADS3_ARATH,Cluster-5155.7,4,NA
ADS3_ARATH,Cluster-5155.6,4,NA
CAS1_PANGI|OXSC_CUCPE,Cluster-40122.1,4,Oxidosqualene cyclase converting oxidosqualene to cycloartenol.|May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function.
XYL1_ARATH,Cluster-34227.0,2,Glycoside hydrolase releasing xylosyl residues from xyloglucan oligosaccharides at the non-reducing end. Has alpha-xylosidase activity against xylan oligosaccharides. Also has alpha-glucosidase activity against p-nitrophenyl-alpha-D-glucopyranoside. No activity against p-nitrophenyl-D-xyloside.
GAPN_NICPL,Cluster-53519.0,2,Important as a means of generating NADPH for biosynthetic reactions.
FRO7_ARATH,Cluster-49466.0,1,Ferric chelate reductase involved in iron mobilization from the cytosol into the chloroplast. May participate in the transport of electrons to a Fe(3+) ion via FAD and heme intermediates. Might be involved iron homeostasis in trichomes.
SRG1_ARATH,Cluster-26136.0,4,NA
AIL1_ARATH,Cluster-37454.0,5,Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways.
C96AF_ARATH,Cluster-48314.0,1,Involved in the formation of secondary alcohols and ketones in stem cuticular wax. Catalyzes the hydroxylation of a methylene unit in the middle of alkane molecules to form secondary alcohols and possibly also a second hydroxylation leading to the corresponding ketones.
C96AF_ARATH,Cluster-48314.2,2,Involved in the formation of secondary alcohols and ketones in stem cuticular wax. Catalyzes the hydroxylation of a methylene unit in the middle of alkane molecules to form secondary alcohols and possibly also a second hydroxylation leading to the corresponding ketones.
ZN257_HUMAN|PRD15_HUMAN,Cluster-37681.0,4,May be involved in transcriptional regulation.|Sequence-specific DNA-binding transcriptional regulator. Plays a role as a molecular node in a transcriptional network regulating embryonic development and cell fate decision. Stimulates the expression of upstream key transcriptional activators and repressors of the Wnt/beta-catenin and MAPK/ERK pathways; respectively; that are essential for naive pluripotency and self-renewal maintenance of embryonic stem cells (ESCs). Specifically promotes SPRY1 and RSPO1 transcription activation through recognition and direct binding of a specific DNA sequence in their promoter regions. Involved in early embryo development (By similarity). Plays also a role in induced pluripotent stem cells (iPSCs) reprogramming (PubMed:28740264).
BDG3_ARATH,Cluster-29636.0,4,Involved in cuticle development and morphogenesis.
PLY5_ARATH|PLY22_ARATH,Cluster-33496.2,4,Pectinolytic enzyme consist of four classes of enzymes: pectin lyase; polygalacturonase; pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes; pectin lyase is the most important in depolymerization of pectin; since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate; the anion; over pectin; the methyl ester.|
PLY_ZINVI,Cluster-33496.1,4,Involved in the degradation of pectin. May assist in the removal and modification of an existing pectin matrix in order to allow the deposition of newly synthesized walls polymers for a specialized function or to create an architecture that is extensible.
SUP_ARATH,Cluster-36290.0,2,Probable transcriptional regulator considered as cadastral protein that acts indirectly to prevent the B class homeotic proteins APETALA3 and perhaps PISTILLATA from acting in the gynoecial whorl. Principal function is to balance cell proliferation in the third and fourth whorls of developing flowers thereby maintaining the boundary between stamens and carpels. May fulfill this role by repressing genes implicated in cell division. Plays equally a role in the determinacy of the floral meristem. Is also required for normal ovule development.
CVIF1_ARATH,Cluster-53102.1,4,NA
CVIF1_ARATH,Cluster-53102.0,4,NA
NCL1_ORYSJ,Cluster-48221.1,3,May function as a sodium/calcium exchanger (NCX) and participate in the maintenance of calcium homeostasis. May play a role abiotic stress responses.
ASOL_BRANA,Cluster-34809.0,4,NA
RPP13_ARATH,Cluster-41171.0,5,Disease resistance protein. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response; which restricts the pathogen growth. In contrast to other resistance proteins; it works independently of ESD1 and NSD1 proteins and does not require the accumulation of salicylic acid; suggesting the existence of an independent signaling pathway. The specificity to avirulence proteins differs in the different cultivars.
MDHP_MEDSA,Cluster-54374.0,3,The chloroplastic; NADP-dependent form is essential for the photosynthesis C4 cycle; which allows plants to circumvent the problem of photorespiration. In C4 plants; NADP-MDH activity acts to convert oxaloacetate to malate in chloroplasts of mesophyll cells for transport to the bundle sheath cells.
CSD_STAAN,Cluster-26338.1,2,Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine; L-cystine; L-selenocysteine; and L-selenocystine to produce L-alanine.
CNGC2_ARATH,Cluster-40899.1,4,Acts as cyclic nucleotide-gated ion channel. Permeable to potassium and calcium in a cyclic nucleotide-dependent fashion (cAMP or cGMP). Could also transport lithium; cesium and rubium and displays a strong selectivity against sodium. Seems to directly participate in pathogen-induced calcium influx. May function in homeostasis; re-establishing ionic balance after defense action and/or other stimuli. Could mediate the initiation of the developmentally regulated cell death programs.
CNGC2_ARATH,Cluster-40899.2,4,Acts as cyclic nucleotide-gated ion channel. Permeable to potassium and calcium in a cyclic nucleotide-dependent fashion (cAMP or cGMP). Could also transport lithium; cesium and rubium and displays a strong selectivity against sodium. Seems to directly participate in pathogen-induced calcium influx. May function in homeostasis; re-establishing ionic balance after defense action and/or other stimuli. Could mediate the initiation of the developmentally regulated cell death programs.
NAC56_ARATH,Cluster-50317.0,7,Transcription factor of the NAC family (Probable). Together with NAC018/NARS2; regulates embryogenesis by regulating the development and degeneration of ovule integuments; a process required for intertissue communication between the embryo and the maternal integument (PubMed:18849494).
PBL19_ARATH,Cluster-38323.0,5,May be involved in plant defense signaling.
ANTR1_ARATH,Cluster-49783.0,2,Specific for inorganic phosphate transport across the thylakoid membrane in a sodium dependent manner. Binds glutamate but cannot transport it. May act as an ascorbate transporter at the thylakoid membrane.
CLCB_ARATH,Cluster-55905.0,4,Voltage-gated chloride channel.
CAP4_ARATH,Cluster-46470.0,4,NA
PM19L_ORYSJ,Cluster-52426.0,4,May be involved in abiotic stress response through abscisic acid-dependent signaling.
STSYN_PEA,Cluster-25277.0,2,Catalyzes stachyose synthesis by transfer of a galactosyl moiety from galactinol to raffinose. Also catalyzes verbascose synthesis by galactosyl transfer from galactinol to stachyose or from one stachyose molecule to another. Oligosaccharides of the raffinose family play a protective role in maturation drying of seeds. They may act as cryoprotectants in frost-hardy plants.
HAT5_ARATH,Cluster-41579.0,1,Probable transcription activator involved in leaf development. Binds to the DNA sequence 5'-CAAT[AT]ATTG-3'.
PTR16_ARATH|PTR19_ARATH,Cluster-16404.1,4,|Low-affinity proton-dependent nitrate transporter. Involved in constitutive nitrate uptake. Not involved in histidine or dipeptides transport. Involved in (+)-abscisic acid (ABA) transport; but not in gibberellin; indole-3-acetic acid or jasmonic acid import. Mediates cellular ABA uptake. Nitrate does not compete with abscisic acid as a substrate of NPF4.6 (PubMed:24084651).
2MMP_ARATH,Cluster-54980.0,4,Matrix metalloproteinases (MMPs) or matrixins may play a role in the degradation and remodeling of the extracellular matrix (ECM) during development or in response to stresses (By similarity). Required for plant growth; morphogenesis; and development with particular relevance for flowering and senescence (PubMed:11726650). Active on McaPLGLDpaAR-NH(2) (QF24) and myelin basic protein (MBP) and; to some extent; on beta-casein (PubMed:24156403).
CCH_ARATH|ATOX1_ARATH,Cluster-47768.0,4,Involved in copper homeostasis. Can complement the yeast mutants atx1 and sod1.|Plays an important role in copper homeostasis by conferring tolerance to excess of copper and subclinical copper deficiency during vegetative stage. Can complement the yeast mutants atx1 and sod1.
LRK64_ARATH,Cluster-37899.0,4,Involved in negative regulation of abscisic acid response in seed germination.
TKTC_SOLTU|TKTC_MAIZE,Cluster-36342.0,2,|Catalyzes the reversible transfer of a two-carbon ketol group from fructose-6-phosphate or sedoheptulose-7-phosphate to glyceraldehyde-3-phosphate to yield xylulose-5-phosphate and erythrose-4-phosphate or ribose-5-phosphate; respectively.
RGLG2_ARATH,Cluster-2578.0,5,E3 ubiquitin-protein ligase that mediates the formation of 'Lys-63'-linked ubiquitin chains. Regulates apical dominance by acting on the auxin transport proteins abundance (PubMed:17586653). Mediates ubiquitination and subsequent proteasomal degradation of ERF053 in response to drought stress. Acts as a negative regulator of drought stress response (PubMed:22095047).
ATAD1_RAT|YJNA_SCHPO,Cluster-34063.0,5,ATPase that plays a critical role in regulating the surface expression of AMPA receptors (AMPAR); thereby regulating synaptic plasticity and learning and memory. Required for NMDA-stimulated AMPAR internalization and inhibition of GRIA1 and GRIA2 recycling back to the plasma membrane; these activities are ATPase-dependent.|
C96AF_ARATH,Cluster-41008.2,1,Involved in the formation of secondary alcohols and ketones in stem cuticular wax. Catalyzes the hydroxylation of a methylene unit in the middle of alkane molecules to form secondary alcohols and possibly also a second hydroxylation leading to the corresponding ketones.
DTX27_ARATH,Cluster-35672.0,7,NA
PTR14_ARATH,Cluster-37581.0,7,Low-affinity proton-dependent bidirectional nitrate transporter. Involved in nitrate loading into xylem and not in nitrate uptake. Not involved in histidine or dipeptides transport.
PV42A_ARATH,Cluster-48630.2,4,Plays redundant role with PV42b in regulating male gametogenesis and pollen tube guidance.
C82A1_PEA|C82A3_SOYBN,Cluster-43104.0,1,Involved in the biosynthetic pathway to 4-hydroxyindole-3-carbonyl nitrile (4-OH-ICN); a cyanogenic metabolite required for inducible pathogen defense. Converts indole-3-carbonyl nitrile (ICN) into 4-OH-ICN (PubMed:26352477). Can hydroxylate xanthotoxin (8-methoxypsoralen) to form 5-hydroxyxanthotoxin (5-hydroxy-8-methoxypsoralen) in vivo and in vitro (PubMed:18291319).|
ALN_ARATH|TSJT1_TOBAC,Cluster-44233.0,5,Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoate by hydrolytic cleavage of the five-member hydantoin ring. Catalyzes the first step of the ureide allantoin degradation followed by the sequential activity of AAH; UGLYAH and UAH which allows a complete purine breakdown without the intermediate generation of urea.|
ALN_ARATH|TSJT1_TOBAC,Cluster-44233.3,5,Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoate by hydrolytic cleavage of the five-member hydantoin ring. Catalyzes the first step of the ureide allantoin degradation followed by the sequential activity of AAH; UGLYAH and UAH which allows a complete purine breakdown without the intermediate generation of urea.|
TSJT1_TOBAC|ALN_ARATH,Cluster-44233.1,5,|Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoate by hydrolytic cleavage of the five-member hydantoin ring. Catalyzes the first step of the ureide allantoin degradation followed by the sequential activity of AAH; UGLYAH and UAH which allows a complete purine breakdown without the intermediate generation of urea.
ALN_ARATH|TSJT1_TOBAC,Cluster-44233.2,5,Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoate by hydrolytic cleavage of the five-member hydantoin ring. Catalyzes the first step of the ureide allantoin degradation followed by the sequential activity of AAH; UGLYAH and UAH which allows a complete purine breakdown without the intermediate generation of urea.|
ENL1_ARATH,Cluster-3354.0,7,Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane; the endolysin can reach the periplasm and break down the peptidoglycan layer.
CK1_ARATH,Cluster-37411.0,4,NA
ATL5_ARATH,Cluster-39779.0,2,May play a role in modulation of fibrillin microfibrils in the extracellular matrix (ECM).
KLH17_HUMAN|KLHL2_HUMAN,Cluster-44354.0,2,Substrate-recognition component of some cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex. The BCR(KLHL17) mediates the ubiquitination and subsequenct degradation of GLUR6. May play a role in the actin-based neuronal function.|Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins; such as NPTXR; leading most often to their proteasomal degradation (By similarity). Responsible for degradative ubiquitination of the WNK kinases WNK1; WNK3 and WNK4. Plays a role in the reorganization of the actin cytoskeleton. Promotes growth of cell projections in oligodendrocyte precursors.
RMA1_CAPAN,Cluster-47554.1,4,E3 ubiquitin-protein ligase required for aquaporin levels regulation.
C76A2_SOLME,Cluster-33649.0,6,NA
ACR2_ARATH|GLYT6_ARATH,Cluster-37321.0,5,May bind amino acids.|May be involved in cell wall biosynthesis.
GIL1_ARATH,Cluster-42773.0,5,Required for red (R) and far red (FR) light-induced and phytochrome-mediated deregulation of negative gravitropism leading to randomization of hypocotyl growth orientation.
SAU50_HELAN,Cluster-48888.0,5,Effector of hormonal and environmental signals in plant growth (By similarity). Involved in heliotropism (PubMed:27493185).
DOF18_ARATH|DOF46_ARATH,Cluster-48055.0,4,Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence.|Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence.
ADRC3_ARATH,Cluster-52359.2,2,Aldehyde reductase that catalyzes the reduction of the aldehyde carbonyl groups on saturated and alpha;beta-unsaturated aldehydes with more than 5 carbons.
RGP1_ORYSJ|RGP1_PEA,Cluster-741.13,5,UDP-L-arabinose mutase involved in the biosynthesis of cell wall non-cellulosic polysaccharides. Catalyzes the interconvertion of UDP-L-arabinopyranose (UDP-Arap) and UDP-L-arabinofuranose (UDP-Araf). Preferentially catalyzes the formation of UDP-Arap from UDP-Araf. At thermodynamic equilibrium in vitro the ratio of the pyranose form over the furanose form is 90:10. Is probably active as heteromer in vivo.|Probable UDP-L-arabinose mutase involved in the biosynthesis of cell wall non-cellulosic polysaccharides (By similarity). Was initially shown to possess an autoglycosylating activity which is dependent on the presence of UDP-glucose and manganese (PubMed:9207152).
GLPT1_ARATH,Cluster-46654.0,1,Responsible for glycerol-3-phosphate uptake.
IAA7_ARATH|IAA14_ARATH,Cluster-36174.0,4,Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs); proteins that bind to the auxin-responsive promoter element (AuxRE). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression.|Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs); proteins that bind to the auxin-responsive promoter element (AuxRE). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression.
SNL6_ORYSJ,Cluster-45338.0,2,Involved in defense response. Required for NPR1/NH1-mediated resistance to the bacterial blight pathogen Xanthomomas oryzae pv. oryzae (Xoo). Required for pathogenesis-related (PR) genes expression. May be involved in lignin biosynthesis.
ATL16_ARATH,Cluster-46403.0,4,May be involved in the early steps of the plant defense signaling pathway.
SAU50_ARATH,Cluster-32945.0,6,Effector of hormonal and environmental signals in plant growth.
LSH3_ARATH,Cluster-30852.0,5,Probable transcription regulator that acts as a developmental regulator by promoting cell growth in response to light (By similarity). Required for the maintenance of the shoot apical meristem and for the formation of lateral organs. Promotes petal formation and growth; but may suppress organ differentiation in the boundary region.
GDU2_ARATH|GDU3_ARATH,Cluster-43192.1,1,Probable subunit of an amino acid transporter involved in the regulation of the amino acid metabolism. Stimulates amino acid export by activating nonselective amino acid facilitators.|Probable subunit of an amino acid transporter involved in the regulation of the amino acid metabolism. Stimulates amino acid export by activating nonselective amino acid facilitators. Acts upstream genes involved in the salicylic acid (SA) pathway and in the geminivirus-host interaction.
MYB40_ANTMA|MYB05_ANTMA,Cluster-43087.0,4,Transcription factor.|
C3H18_ORYSJ,Cluster-44399.0,2,Plays a central role in integrating RNA silencing and chromatin signals in 21 nt siRNA-dependent DNA methylation on cytosine pathway leading to transcriptional gene silencing of specific sequences. Involved in a chromatin-based RNA silencing pathway that encompasses both post-transcriptional gene silencing (PTGS) (e.g. RDR1; RDR6 and AGO2) and transcriptional gene silencing (TGS) (e.g. siRNA-dependent DNA methylation and histone H3) components. Mediates siRNA accumulation at specific chromatin loci. Binds H3K4me0 through its PHD to enforce low levels of H3K4 methylation and gene silencing at a subset of genomic loci.
NLTP2_PRUAR,Cluster-29917.1,1,Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
PMA8_ARATH,Cluster-23290.0,7,The plasma membrane H(+) ATPase of plants and fungi generates a proton gradient that drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.
PRS2_SOLTU,Cluster-52454.0,4,Selectively cleaves synthetic peptide substrates of trypsin. Activates the epithelial sodium channel ENaC.
PRS2_SOLTU,Cluster-48154.0,5,Selectively cleaves synthetic peptide substrates of trypsin. Activates the epithelial sodium channel ENaC.
POR_DAUCA,Cluster-36826.0,2,Phototransformation of protochlorophyllide (Pchlide) to chlorophyllide (Chlide).
UGT2_GARJA,Cluster-7572.1,7,Iridoid glucosyltransferase acting on genipin and 7-deoxyloganetin. No activity with 7-deoxyloganetic acid. Involved in geniposide biosynthesis.
TCP13_ARATH,Cluster-53121.0,4,Plays a pivotal role in the control of morphogenesis of shoot organs by negatively regulating the expression of boundary-specific genes such as CUC genes; probably through the induction of miRNA (e.g. miR164). Binds to the 3'-ACC-5' repeats in the light-responsive promoter (LRP) of psbD; and activates its transcription. Participates in ovule develpment (PubMed:25378179).
GGPPS_CAPAN,Cluster-29319.0,3,Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate.
ABIL2_ARATH,Cluster-32065.1,3,Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex.
AB29G_ARATH,Cluster-54138.0,5,NA
BAMT_ANTMA,Cluster-44630.1,3,Converts benzoic acid into the volatile ester methyl benzoates. This scent; mostly produced in a rhythmical; diurnal manner; attracts the pollinators.
BAMT_ANTMA,Cluster-44630.0,3,Converts benzoic acid into the volatile ester methyl benzoates. This scent; mostly produced in a rhythmical; diurnal manner; attracts the pollinators.
CAMT3_ARATH|CHR28_ARATH,Cluster-56864.0,2,Methylates caffeoyl-CoA to feruloyl-CoA and 5-hydroxyferuloyl-CoA to sinapoyl-CoA. Plays a role in the synthesis of feruloylated polysaccharides. Involved in the reinforcement of the plant cell wall. Also involved in the responding to wounding or pathogen challenge by the increased formation of cell wall-bound ferulic acid polymers.|
CAMT3_ARATH|CAMT1_ARATH,Cluster-34263.0,2,Methylates caffeoyl-CoA to feruloyl-CoA and 5-hydroxyferuloyl-CoA to sinapoyl-CoA. Plays a role in the synthesis of feruloylated polysaccharides. Involved in the reinforcement of the plant cell wall. Also involved in the responding to wounding or pathogen challenge by the increased formation of cell wall-bound ferulic acid polymers.|Methylates caffeoyl-CoA to feruloyl-CoA and 5-hydroxyferuloyl-CoA to sinapoyl-CoA. Plays a role in the synthesis of feruloylated polysaccharides. Involved in the reinforcement of the plant cell wall. Also involved in the responding to wounding or pathogen challenge by the increased formation of cell wall-bound ferulic acid polymers.
U74F2_ARATH,Cluster-47797.1,6,Glycosyltransferase that glucosylates benzoic acid and derivatives. Substrate preference is benzoic acid > salicylic acid (SA) > 3-hydroxybenzoic acid > 4-hydroxybenzoic acid. Catalyzes the formation of both SA 2-O-beta-D-glucoside (SAG) and SA glucose ester (SGE). Has high affinity for the tryptophan precursor anthranilate. Catalyzes the formation of anthranilate glucose ester. Is the major source of this activity in the plant.
C76A2_SOLME|C76A1_SOLME,Cluster-37108.0,2,|Converts L-DOPA to cyclo-DOPA in the betalain pathway. Provides the cyclo-DOPA moiety of all red betacyanins.
SBT54_ARATH,Cluster-25640.0,5,NA
BGL06_ORYSJ|BGL34_ORYSJ,Cluster-36653.0,1,|Hydrolyzes sinigrin and; with lower efficiency; p-nitrophenyl beta-D-glucoside.
HAK5_ORYSJ,Cluster-33474.0,4,High-affinity potassium transporter.
STY13_ARATH,Cluster-52808.0,1,Serine/threonine protein kinase that phosphorylates proteins on serine; threonine and tyrosine residues.
TCP19_ARATH,Cluster-34153.0,4,Mediates uptake of L-cystine; the oxidized form of L-cysteine.
IQD31_ARATH,Cluster-46664.0,5,Guanine nucleotide exchange factor for ARF1 and ARF6 (PubMed:24058294). Guanine nucleotide exchange factor activity is enhanced by lipid binding (PubMed:24058294). Accelerates GTP binding by ARFs of all three classes. Guanine nucleotide exchange protein for ARF6; mediating internalisation of beta-1 integrin.
ARG7_VIGRR|SAU21_ARATH,Cluster-55085.1,1,|Functions as positive effectors of cell expansion through modulation of auxin transport.
ORR9_ORYSJ|ORR4_ORYSJ,Cluster-34076.0,5,Functions as response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Type-A response regulators seem to act as negative regulators of the cytokinin signaling.|Functions as response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Type-A response regulators seem to act as negative regulators of the cytokinin signaling.
KPPR_WHEAT,Cluster-16623.0,2,NA
GPPL1_ARATH,Cluster-33886.0,2,Catalyzes the SAM-dependent methylation of geranyl diphosphate (GPP) to yield (E)-2-methylgeranyl diphosphate (2-MeGPP).
TNG2_MOUSE,Cluster-57253.0,4,NA
TNG2_BOVIN,Cluster-57253.1,4,May play a role in Golgi organization.
PTL_ARATH,Cluster-42340.0,6,Transcription factor that prevents growth. Regulates perianth architecture in flower; mostly in the second whorl; probably by suppressing growth between initiating sepals; ensuring that they remain separate; and by modulating organ shapes. Required for the establishment of auxin flux.
ERDL5_ARATH|ESL1_ARATH,Cluster-20765.4,1,Sugar transporter.|Sugar transporter. Transports monosaccharides across the vacuolar membrane independently from a proton gradient. May function coordinately with the vacuolar invertase to regulate osmotic pressure by affecting the accumulation of sugar in the cells under abiotic stress conditions.
ERDL5_ARATH|ESL1_ARATH,Cluster-20765.3,3,Sugar transporter.|Sugar transporter. Transports monosaccharides across the vacuolar membrane independently from a proton gradient. May function coordinately with the vacuolar invertase to regulate osmotic pressure by affecting the accumulation of sugar in the cells under abiotic stress conditions.
MF14B_HUMAN|MF14A_HUMAN,Cluster-29595.0,4,|
CRTS1_ONCHC|CRTSO_DAUCA,Cluster-34255.0,1,Carotene cis-trans-isomerase that converts 7;9;9'-tri-cis-neurosporene to 9'-cis-neurosporene and 7;9;9';7'-tetra-cis-lycopene (also known as prolycopene) into all-trans-lycopene. Isomerization requires redox-active components; suggesting that isomerization is achieved by a reversible redox reaction acting at specific double bonds. Isomerizes adjacent cis-double bonds at C7 and C9 pairwise into the trans-configuration; but is incapable of isomerizing single cis-double bonds at C9 and C9'.|Carotene cis-trans-isomerase that converts 7;9;9'-tri-cis-neurosporene to 9'-cis-neurosporene and 7;9;9';7'-tetra-cis-lycopene (also known as prolycopene) into all-trans-lycopene. Isomerization requires redox-active components; suggesting that isomerization is achieved by a reversible redox reaction acting at specific double bonds. Isomerizes adjacent cis-double bonds at C7 and C9 pairwise into the trans-configuration; but is incapable of isomerizing single cis-double bonds at C9 and C9'.
C71DF_MENPI|C7D55_HYOMU,Cluster-52300.0,4,Hydroxylates (-)-(4S)-limonene to (-)-trans-isopiperitenol; a precursor of (-)-menthol; responsible for the cooling sensation of peppermint. Fluorinated substrate analogs are hydroxylated with the same regio- and stereochemistry.|Involved in the biosynthesis of solavetivone; a potent antifungal phytoalexin. Catalyzes the successive and independent hydroxylations of premnaspirodiene and solavetivol. The first hydroxylation step is 3-fold more efficient than the second hydroxylation reaction.
FAO4A_ARATH,Cluster-50416.0,5,Long-chain fatty alcohol oxidase involved in the omega-oxidation pathway of lipid degradation.
ERG3_ORYSJ,Cluster-35872.0,4,NA
LFG5_ARATH,Cluster-28965.1,4,Part of the flagellar gene cluster Flag-2. However; the Flag-2 flagellar system could be inactive in strain 042 due to a frameshift in lfgC.
F3PH_ARATH|C71A1_PERAE,Cluster-38705.0,3,|Involved in the metabolism of compounds associated with the development of flavor in the ripening fruit process; possibly by acting as trans-cinnamic acid 4-hydrolase.
CAB6_ARATH|CB11_SOLLC,Cluster-44825.0,2,The light-harvesting complex (LHC) functions as a light receptor; it captures and delivers excitation energy to photosystems with which it is closely associated.|
LOB_ARATH|LBD25_ARATH,Cluster-43884.0,6,Not known; ectopic expression of LOB leads to alterations in the size and shape of leaves and floral organs and causes male and female sterility.|
SMO11_ARATH,Cluster-37120.0,4,Non-heme iron oxygenase involved in sterols biosynthesis. 4;4-dimethyl-9-beta;19-cyclopropylsterols such as 24-methylenecycloartanol are the preferred substrates.
AKT2_ARATH,Cluster-27699.0,1,Highly selective and weak inward-rectifying potassium channel. Plays a role in both loading and unloading potassium into/from the phloem sap. Seems to control sugar loading into phloem via a voltage-dependent process. Blocked by physiological concentrations of external calcium and by external acidification. May interact with the cytoskeleton or with regulatory proteins. Dephosphorylation by PP2CA not only leads to the inhibition of potassium currents but also to an increase of the voltage-dependence of the channel. Regulated by the CBL4/CIPK6 calcium sensor/protein kinase complex via a kinase interaction-dependent but phosphorylation-independent translocation of the channel to the plasma membrane.
NIP61_ARATH,Cluster-26144.1,4,Transports glycerol; urea and formamide; in Xenopus laevis oocytes. Very low water transport activity.
NIP61_ARATH,Cluster-26144.0,4,Transports glycerol; urea and formamide; in Xenopus laevis oocytes. Very low water transport activity.
NIP61_ARATH,Cluster-26144.3,4,Transports glycerol; urea and formamide; in Xenopus laevis oocytes. Very low water transport activity.
CSPLD_VITVI|IDM1_ARATH,Cluster-38161.2,5,|Histone H3 acetyltransferase that binds methylated DNA at chromatin sites lacking histone H3K4 di- or trimethylation and catalyzes H3K18 and H3K23 acetylation (PubMed:22733760; PubMed:22700931). Prevents the transcriptional silencing of transgenes and of some endogenous genes (PubMed:22733760; PubMed:22700931). Requires the presence of IDM2 for efficient H3K18 acetylation; but not for H3K23 acetylation (PubMed:25002145).
SCP50_ARATH,Cluster-42858.0,1,Probable carboxypeptidase.
BH151_ARATH,Cluster-28015.0,4,Transcription factor that modulates the balance between cellular proliferation and differentiation in root growth. Does not act through cytokinin and auxin signaling; but by repressing peroxidase expression in the elongation zone.
ORP1C_ARATH|ORP1A_ARATH,Cluster-43996.0,1,May be involved in the transport of sterols.|May be involved in the transport of sterols.
CB24_TOBAC,Cluster-21980.0,2,The light-harvesting complex (LHC) functions as a light receptor; it captures and delivers excitation energy to photosystems with which it is closely associated.
CB2G_SOLLC,Cluster-1406.14,2,The light-harvesting complex (LHC) functions as a light receptor; it captures and delivers excitation energy to photosystems with which it is closely associated.
CB23_SOLLC,Cluster-8861.1,2,The light-harvesting complex (LHC) functions as a light receptor; it captures and delivers excitation energy to photosystems with which it is closely associated.
YUC6_ARATH|MS5L2_ARATH,Cluster-44595.0,5,Involved in auxin biosynthesis via the indole-3-pyruvic acid (IPA) pathway. Also able to convert in vitro phenyl pyruvate (PPA) to phenyl acetic acid (PAA). Required for the formation of floral organs and vascular tissues. Belongs to the set of redundant YUCCA genes probably responsible for auxin biosynthesis in shoots.|Probably involved in the regulation of cell division.
SALR_PAPBR|NU5M_WHEAT,Cluster-34052.1,1,Involved in biosynthesis of morphinan-type benzylisoquinoline alkaloids. Catalyzes the stereospecific conversion of salutaridine to salutaridinol.|Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
TIP41_ARATH,Cluster-26059.0,7,Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. Transports urea in yeast cells in a pH-independent manner.
CB13_SOLLC|LHCA3_ARATH,Cluster-41771.0,2,The light-harvesting complex (LHC) functions as a light receptor; it captures and delivers excitation energy to photosystems with which it is closely associated.|The light-harvesting complex (LHC) functions as a light receptor; it captures and delivers excitation energy to photosystems with which it is closely associated; here photosystem I.
PP159_ARATH|CML3_ARATH,Cluster-30568.0,5,|Potential calcium sensor.
BGA14_ARATH,Cluster-49855.0,4,NA
AL2C4_ARATH,Cluster-33142.0,2,Involved in ferulic acid and sinapic acid biosynthesis by oxidation of conyferylaldehyde and sinapaldehyde; respectively. Can oxidize L-lactaldehyde. Possesses activity on acetaldehyde and glycolaldehyde in vitro.
C71DA_SOYBN,Cluster-50950.0,1,NA
AGD14_ARATH,Cluster-39420.0,4,GTPase-activating protein (GAP) for ADP ribosylation factor (ARF).
CSLE6_ORYSJ,Cluster-54796.0,4,Thought to be a Golgi-localized beta-glycan synthase that polymerize the backbones of noncellulosic polysaccharides (hemicelluloses) of plant cell wall.
USPAL_ARATH,Cluster-39620.0,5,Required for resistance to DNA-damaging agents.
PIP12_ARATH|PIP15_ARATH,Cluster-36657.3,4,Water channel required to facilitate the transport of water across cell membrane. Essential for the water permeability of the plasma membrane and for the morphology of the root system. Its function is impaired by Hg(2+). Inhibited by cytosolic acidosis which occurs during anoxia in roots.|Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
ZFP10_ARATH,Cluster-10515.0,2,NA
CCD31_ARATH|CCD32_ARATH,Cluster-42264.0,5,|
CAAT1_ARATH,Cluster-36337.0,5,NA
BRG3_ARATH,Cluster-52261.0,5,Probable E3 ubiquitin-protein ligase. Has no effect on the stability of the DELLA proteins.
MY106_ARATH,Cluster-2119.0,5,Functions as a repressor of epidermal cell outgrowth and negatively regulate trichome branch formation (PubMed:18805951; PubMed:21070410). Acts as both a positive and negative regulator of cellular outgrowth. Promotes both trichome expansion and branch formation (PubMed:21070410). Coordinately with WIN1/SHN1; participates in the regulation of cuticle biosynthesis and wax accumulation in reproductive organs and trichomes. Functions in cuticle nanoridge formation in petals and stamens; and in morphogenesis of petal conical cells and trichomes (PubMed:23709630). May play a role in the regulation of cuticle formation in vegetative organs (PubMed:24169067).
UNE10_ARATH,Cluster-27027.0,1,Required during the fertilization of ovules by pollen.
GAT22_ARATH|GAT21_ARATH,Cluster-49590.0,2,Transcriptional regulator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters (PubMed:22102866; PubMed:25077795). Involved in the modulation of chloroplast development; growth and division in a cytokinin-dependent manner (PubMed:22102866; PubMed:22811435). Repressor of the gibberellic acid (GA) signaling pathway that regulates flowering and modulates greening; in a SOC1-dependent manner (PubMed:20844019; PubMed:23739688; PubMed:25077795). Prevents the accumulation of SOC1 during flowering (PubMed:23739688). Promotes chlorophyll biosynthesis throughout the plant; by regulating chlorophyll biosynthetic genes (e.g. HEMA1 and GUN4) and chloroplast localized glutamate synthase (e.g. GLU1) (PubMed:18417639; PubMed:20844019; PubMed:21453984; PubMed:22102866; PubMed:23878229; PubMed:25077795). Involved in the regulation of sugar-sensing genes (e.g. HXK1; HXK2; STP13 and PLT6) (PubMed:18417639). Regulator of germination; senescence; elongation growth and flowering time (PubMed:20844019; PubMed:22102866; PubMed:23878229). Influences also leaf starch content (PubMed:22102866).|Transcriptional regulator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters (PubMed:22102866; PubMed:25077795). Involved in the modulation of chloroplast development; growth and division in a cytokinin-dependent manner (PubMed:22102866; PubMed:22811435). Repressor of the gibberellic acid (GA) signaling pathway that represses flowering and modulates greening; in a SOC1-dependent manner (PubMed:20844019; PubMed:23739688; PubMed:25077795). Prevents the accumulation of SOC1 during flowering (PubMed:23739688). Promotes chlorophyll biosynthesis throughout the plant; by regulating chlorophyll biosynthetic genes (e.g. HEMA1 and GUN4) and chloroplast localized glutamate synthase (e.g. GLU1) (PubMed:18417639; PubMed:20844019; PubMed:22102866; PubMed:23878229; PubMed:25077795). Involved in the regulation of sugar-sensing genes (e.g. HXK1; HXK2; STP13 and PLT6) (PubMed:18417639). Regulator of germination; senescence; elongation growth and flowering time (PubMed:20844019; PubMed:22102866; PubMed:23878229). Influences also leaf starch content (PubMed:22102866).
GAT22_ARATH,Cluster-24286.0,5,Transcriptional regulator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters (PubMed:22102866; PubMed:25077795). Involved in the modulation of chloroplast development; growth and division in a cytokinin-dependent manner (PubMed:22102866; PubMed:22811435). Repressor of the gibberellic acid (GA) signaling pathway that regulates flowering and modulates greening; in a SOC1-dependent manner (PubMed:20844019; PubMed:23739688; PubMed:25077795). Prevents the accumulation of SOC1 during flowering (PubMed:23739688). Promotes chlorophyll biosynthesis throughout the plant; by regulating chlorophyll biosynthetic genes (e.g. HEMA1 and GUN4) and chloroplast localized glutamate synthase (e.g. GLU1) (PubMed:18417639; PubMed:20844019; PubMed:21453984; PubMed:22102866; PubMed:23878229; PubMed:25077795). Involved in the regulation of sugar-sensing genes (e.g. HXK1; HXK2; STP13 and PLT6) (PubMed:18417639). Regulator of germination; senescence; elongation growth and flowering time (PubMed:20844019; PubMed:22102866; PubMed:23878229). Influences also leaf starch content (PubMed:22102866).
CCD51_ARATH|CCD52_ORYSJ,Cluster-44740.0,2,Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.|
PSKR1_DAUCA,Cluster-49688.0,2,Phytosulfokine receptor with a serine/threonine-protein kinase activity. Regulates; in response to phytosulfokine binding; a signaling cascade involved in plant cell differentiation; organogenesis and somatic embryogenesis.
C83B1_ARATH,Cluster-38996.0,1,Involved in the metabolism of aromatic oximes. Catalyzes the oxime metabolizing step in indole glucosinolate biosynthesis by converting indole-3-acetaldoxime into indole-3-S-alkyl-thiohydroximate. Probably required for glucosinolate activation in response to pathogens. Functions in auxin homeostasis because indole-3-acetaldoxime also serves as a precursor for auxin biosynthesis. Specifically metabolizes (E)-p-hydroxyphenylacetaldoxime into an S-alkyl-thiohydroximate (PubMed:26361733).
C83B1_ARATH|C71BX_ARATH,Cluster-31154.0,3,Involved in the metabolism of aromatic oximes. Catalyzes the oxime metabolizing step in indole glucosinolate biosynthesis by converting indole-3-acetaldoxime into indole-3-S-alkyl-thiohydroximate. Probably required for glucosinolate activation in response to pathogens. Functions in auxin homeostasis because indole-3-acetaldoxime also serves as a precursor for auxin biosynthesis. Specifically metabolizes (E)-p-hydroxyphenylacetaldoxime into an S-alkyl-thiohydroximate (PubMed:26361733).|
BOR6_ARATH|BOR4_ARATH,Cluster-23942.0,7,Probable boron transporter. Boron is essential for maintaining the integrity of plants cell walls.|Efflux-type boron transporter polarly localized in roots. Boron is essential for maintaining the integrity of plants cell walls.
CSPLC_POPTR,Cluster-44687.0,7,NA
ICR2_ARATH,Cluster-27225.1,1,Acts as a scaffold; mediating interaction of ROPs with different proteins.
HEX6_RICCO,Cluster-40395.0,1,Active uptake of hexoses. Probable glucose/hydrogen symport.
ZWIP5_ARATH,Cluster-48394.0,2,Probable transcriptional regulator.
RAD_ANTMA,Cluster-2971.21,1,Involved in the dorsovental asymmetry of flowers. Promotes dorsal identity.
HMA6_ARATH|FLZ8_ARATH,Cluster-38960.6,1,Mediates copper transfer across the plastid envelope. Required for the delivery of copper into the plastid stroma; which is essential for the function of copper proteins. Seems to be selective for monovalent copper Cu(+) transport. Plays also a role in glucose signaling-mediated cell proliferation of root meristem in non-green tissues.|May act as an adapter to facilitate the interaction of SnRK1 complex with effector proteins; conferring tissue- and stimulus-type specific differences in the SnRK1 regulation pathway.
MAOC_FLAPR,Cluster-16193.2,1,NA
PMTR_ARATH,Cluster-26479.0,7,May be involved in the synthesis of homogalacturonan. Required for normal cell adhesion and plant development.
DIR19_ARATH,Cluster-34462.0,1,Dirigent proteins impart stereoselectivity on the phenoxy radical-coupling reaction; yielding optically active lignans from two molecules of coniferyl alcohol in the biosynthesis of lignans; flavonolignans; and alkaloids and thus plays a central role in plant secondary metabolism.
D14_ORYSJ|KAI2_ARATH,Cluster-28871.0,1,|Involved in seed germination and seedling development. Essential for plant responses to karrikins; a class of butenolide compounds; structurally similar to strigolactones; released from burning vegetation that stimulate seed germination and enhance seedling photomorphogenesis. KAI2 is not required for strigolactone-mediated responses; but MAX2 is necessary for responses to karrikins and strigolactones (PubMed:20864454; PubMed:22357928; PubMed:23142794; PubMed:23301669). Lacks detectable hydrolase activity against karrikin (PubMed:23613584). Karrikin binding induces a conformational change (PubMed:23613584).
ACT_MANSE,Cluster-8600.0,7,Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
UXS2_ARATH,Cluster-39218.0,4,Catalyzes the NAD-dependent decarboxylation of UDP-glucuronic acid to UDP-xylose. Necessary for the biosynthesis of the core tetrasaccharide in glycosaminoglycan biosynthesis.
GDI_ARATH,Cluster-53112.0,7,Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them; and the subsequent binding of GTP.
PITC_DICDI|PDR16_YEAST,Cluster-35862.0,6,Has phosphatidylinositol transfer activity.|
LRK10_WHEAT|LRL12_ARATH,Cluster-49091.0,3,Involved in resistance response to the pathogenic fungus Alternaria brassicicola.|
WOX1_ARATH,Cluster-53455.0,5,Transcription factor which may be involved in developmental processes.
MPK15_ARATH,Cluster-24940.0,4,NA
RNP1_ARATH,Cluster-54099.0,7,Involved with pre-mRNA processing. Forms complexes (ribonucleosomes) with at least 20 other different hnRNP and heterogeneous nuclear RNA in the nucleus.|Involved in the packaging of pre-mRNA into hnRNP particles; transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection.
WTR45_ARATH,Cluster-33627.0,5,NA
MYOB6_ARATH,Cluster-55556.0,4,Probable membrane-anchored myosin receptors.
PSS1_ARATH|PSS2_ORYSJ,Cluster-43440.0,3,Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. Is essential for phosphatidylserine (PS) biosynthesis and PE seems to be the most plausible substrate. Plays an important role in microspore maturation.|Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine.
MSL8_ARATH,Cluster-41736.3,5,Mechanosensitive channel that opens in response to stretch forces in the membrane lipid bilayer. Exhibits a 6.3-fold preference for chloride over sodium. Regulates osmotic forces during pollen hydration and germination.
AAE_RAUSE|GDL74_ARATH,Cluster-45080.0,4,Deacetylates 17-O-acetylajmaline and 17-O-acetylnorajmaline; but is inactive toward other acetylated alkaloids.|
GLUD1_ORYSJ,Cluster-27393.0,7,Seed storage protein.
RNHX1_ARATH,Cluster-46982.3,2,Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
RNHX1_ARATH,Cluster-46982.7,2,Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
FAD12_PUNGR,Cluster-47904.0,4,Delta(12)-fatty acid desaturase producing in a heterologous system linoleic acid (18:2(9Z;12Z)) and to a lower extent hexadecadienoic acid (16:2(9Z;12Z)).
CCD33_ARATH,Cluster-22719.3,2,NA
GG3_ARATH,Cluster-54739.0,2,Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity; for replacement of GDP by GTP; and for G protein-effector interaction.
E70A1_ARATH,Cluster-55554.0,4,Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane during regulated or polarized secretion. Involved in polarized cell growth and organ morphogenesis. Involved in polarized cell growth and organ morphogenesis. During cytokinesis; involved in cell plate initiation; cell plate maturation and formation of new primary cell wall. Participates in polarized pectin delivery required for the polarized development of the mucilage-producing volcano cells of the seed coat. Involved in the recycling and localization of auxin efflux carriers PIN1 and PIN2; and thus in polar auxin transport regulation. Functions in vesicle trafficking in tracheary elements to regulate patterned secondary cell wall thickening.
AVT1A_ARATH,Cluster-31972.0,4,Required for the vacuolar uptake of large neutral amino acids including tyrosine; glutamine; asparagine; isoleucine and leucine. Requires ATP for function.
SKOR_ARATH|KOR1_ORYSJ,Cluster-47122.0,4,Highly selective outward-rectifying potassium channel. Involved in potassium release into the xylem sap toward the shoots. Assuming opened or closed conformations in response to the voltage difference across the membrane; the channel is activated by depolarization. The voltage-dependence of the channel is abolished by internal or external acidification. May interact with the cytoskeleton or with regulatory proteins.|Probable outward-rectifying potassium channel.
FLOT1_MEDTR,Cluster-32766.0,7,May act as a scaffolding protein within caveolar membranes; functionally participating in formation of caveolae or caveolae-like vesicles (By similarity). May be involved in nodule formation.
RNHX1_ARATH,Cluster-5243.0,5,Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
CLSY3_ARATH,Cluster-30156.0,2,Probable chromatin remodeling factor.
CLSY3_ARATH,Cluster-33487.0,2,Probable chromatin remodeling factor.
TL29_SOLLC,Cluster-41139.0,2,NA
NRAM6_ARATH|NRAM3_ORYSJ,Cluster-37151.3,4,Probable intracellular cadmium (Cd) transporter that participates in the distribution or availability of Cd within the cell.|Probable metal transporter.
NRAM6_ARATH,Cluster-37151.0,4,Probable intracellular cadmium (Cd) transporter that participates in the distribution or availability of Cd within the cell.
NRAM6_ARATH|NRAM3_ORYSJ,Cluster-37151.2,4,Probable intracellular cadmium (Cd) transporter that participates in the distribution or availability of Cd within the cell.|Probable metal transporter.
CDSP_ARATH,Cluster-37748.0,2,Probable thiol-disulfide oxidoreductase involved in resistance to oxidative stress. May participate in the reduction of alkyl hydroperoxides derived from oxidative stress by acting as a physiological electron donor to the BAS1 peroxiredoxin. May regenerate methionine sulfoxide reductase B1 (MSRB1) activity through sulfenic acid reduction.
SY124_ARATH,Cluster-23930.0,4,Vesicle trafficking protein that functions in the secretory pathway.
Y1133_ARATH,Cluster-52488.0,4,NA
SUI1_MAIZE,Cluster-40971.0,4,NA
DOT3_ARATH|RPT3_ARATH,Cluster-3209.1,2,May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Involved in leaf vasculature patterning (PubMed:18643975).|May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Signal transducer of the phototropic response and photo-induced movements. Involved in the phot1 pathway under low blue light (LBL) fluence rate and in the phot2 pathway under higher fluence rate of blue light (HBL). Necessary for root and hypocotyl phototropisms; but not for the regulation of stomata opening. Not involved in chloroplast accumulation and translocation.
IRT1_ARATH|ZIP10_ARATH,Cluster-45605.0,2,High-affinity iron transporter that plays a key role in the uptake of iron from the rhizosphere across the plasma membrane in the root epidermal layer. Acts as the principal regulator of iron homeostasis in planta. Also mediates the heavy metals uptake under iron-deficiency by its ability to transport cobalt; cadmium; manganese and/or zinc ions.|Probably mediates zinc uptake from the rhizosphere.
RPB2_SOLLC,Cluster-16169.0,5,DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB2 is part of the core element with the central large cleft; the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template.
PERQ_SUASA,Cluster-27873.0,2,Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols; respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
BCAT2_ARATH,Cluster-30743.0,5,Converts 2-oxo acids to branched-chain amino acids. Shows activity with L-Leu; L-Ile and L-Val as amino donors and 2-oxoglutarate as an amino acceptor; but no activity for D-isomers of Leu; Ile; Val; Asp; Glu or Ala.
HD3A_ORYSJ,Cluster-28186.0,4,NA
PLP6_ARATH,Cluster-39760.0,3,Possesses non-specific lipolytic acyl hydrolase (LAH) activity. Hydrolyzes phospholipids as well as galactolipids. May play a role in disease resistance.
BGL13_ORYSJ|BGL12_ORYSI,Cluster-28599.0,4,|
BGL11_ORYSJ,Cluster-35407.0,4,NA
BGL12_ORYSJ|BGL12_ORYSI,Cluster-25143.0,4,Hydrolyzes p-nitrophenyl beta-D-glucoside; p-nitrophenyl beta-D-galactoside; p-nitrophenyl beta-D-xyloside; p-nitrophenyl beta-D-fucoside; p-nitrophenyl beta-L-arabinoside; cello-oligosaccharides and laminaribiose.|
PGIP_PYRCO,Cluster-23372.0,2,Inhibitor of fungal polygalacturonase. It is an important factor for plant resistance to phytopathogenic fungi.
PAO1_ARATH,Cluster-30348.0,5,Flavoenzyme involved in polyamine back-conversion (PubMed:16778015; PubMed:20532512; PubMed:21081665; PubMed:26973665). Catalyzes the oxidation of the secondary amino group of polyamines; such as spermine and its acetyl derivatives (PubMed:16778015; PubMed:20532512; PubMed:21081665). Substrate preference is thermospermine > norspermine > spermine > N(1)-acetylspermine (PubMed:16778015; PubMed:21081665). No activity detected when putrescine; spermidine or N(1)-acetylspermidine are used as substrates (PubMed:16778015). Plays an important role in the regulation of polyamine intracellular concentration (Probable) (PubMed:26973665). Involved in the production of hydrogen peroxide in response to salt and cold stresses (PubMed:26973665).
ADH3_SOLTU|ADH1_MAIZE,Cluster-15213.3,4,|
PLCD2_ARATH|PLCD4_ARATH,Cluster-36699.0,4,The production of the second messenger molecules diacylglycerol (DAG) and inositol 1;4;5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. At physiological calcium concentration; the preferred substrate is phosphatidylinositol 4;5-bisphosphate versus phosphatidylinositol.|The production of the second messenger molecules diacylglycerol (DAG) and inositol 1;4;5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
POLN_ABPVR,Cluster-57713.0,1,Replicase polyprotein contains helicase; VPg; protease and RNA-directed RNA polymerase functions.|RNA-directed RNA polymerase replicates genomic and antigenomic RNA and transcribes the vial genome.|The protease generates mature viral proteins from the precursor polyprotein.|VPg is covalently linked to the 5'-end of genomic RNA.
PNSL4_ARATH,Cluster-49030.0,3,NDH shuttles electrons from NAD(P)H:plastoquinone; via FMN and iron-sulfur (Fe-S) centers; to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation; and thus conserves the redox energy in a proton gradient (Probable). PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity). Seems to be essential for stabilizing the NDH subcomplex A (PubMed:19903870).
AB42G_ORYSJ|AB36G_ARATH,Cluster-33994.0,5,May be a general defense protein.|Key factor that controls the extent of cell death in the defense response. Necessary for both callose deposition and glucosinolate activation in response to pathogens. Required for limiting invasion by nonadapted powdery mildews. Confers resistance to cadmium (Cd) and lead (Pb); probably as an efflux pump of Cd2+ or Cd conjugates; and possibly; of chemicals that mediate pathogen resistance.
CCD22_ORYSJ|CCD21_ORYSJ,Cluster-49193.0,5,|Involved in regulation of NF-kappa-B signaling. Promotes ubiquitination of I-kappa-B-kinase subunit IKBKB and its subsequent proteasomal degradation leading to NF-kappa-B activation; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. May down-regulate NF-kappa-B activity via association with COMMD1 and involving a CUL2-dependent E3 ubiquitin ligase complex. Regulates the cellular localization of COMM domain-containing proteins; such as COMMD1 and COMMD10. Plays a role in copper ion homeostasis. Involved in copper-dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery; the function is proposed to depend on its association within the CCC complex and cooperation with the WASH complex on early endosomes.
CWPX_ARATH,Cluster-22036.2,4,NA
CCR1_ARATH,Cluster-31030.0,4,NA
GALE2_CYATE,Cluster-34349.0,5,NA
GALE2_CYATE,Cluster-27758.3,4,NA
SR43C_ARATH,Cluster-14621.0,2,Component of the chloroplast signal recognition particle pathway. Required for post-translational targeting of proteins into the thylakoid membrane but seems to be dispensable for co-translational targeting with a translating ribosome present. May be able to function independently of cpFTSY and FFC/cpSRP54 in targeting LHCPs to the thylakoids. Acts as a highly specific chaperone for LHCPs; preventing aggregation and being able to dissolve aggregates.
KN14F_ARATH,Cluster-52352.0,5,NA
ODBA2_ARATH|ODBA1_ARATH,Cluster-52206.0,5,The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1); lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).|The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1); lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). Required during sugar starvation.
LOR6_ARATH,Cluster-24130.0,3,Might be related to the phospholipid scramblase and tubby-like superfamily of membrane tethered transcription factors.
WRK48_ARATH,Cluster-36087.0,6,Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'); a frequently occurring elicitor-responsive cis-acting element.
IQM6_ARATH|IQM2_ARATH,Cluster-41582.0,5,May be involved in biotic and abiotic stress responses.|May be involved in biotic and abiotic stress responses.
BH137_ARATH,Cluster-5935.0,2,NA
BH137_ARATH,Cluster-6626.0,2,NA
ZOG_PHALU,Cluster-36908.0,1,May regulate active VS. Storage forms of cytokinins and could have an impact on seed growth. Can also use UDP-xylose to catalyzes the formation of O-xylosylzeatin but at much lower affinity.
PPH_ARATH|Y2734_MYCBO,Cluster-39160.0,1,Alpha/beta hydrolase dephytylating specifically the Mg-free chlorophyll pigment (pheophytin); yielding pheophorbide. No activity on chlorophyll. Belongs to the chlorophyll catabolic enzymes (CCEs).|May play a role in the intracellular transport of hydrophobic ligands.
RAV1_ARATH,Cluster-44982.0,2,Binds specifically to bipartite recognition sequences composed of two unrelated motifs; 5'-CAACA-3' and 5'-CACCTG-3'. May function as negative regulator of plant growth and development.
PUB33_ARATH|PUB36_ARATH,Cluster-51149.0,4,Functions as an E3 ubiquitin ligase.|Functions as an E3 ubiquitin ligase.
RTNLE_ARATH|RTNLA_ARATH,Cluster-46970.0,6,Component of the spliceosomal U1 snRNP; which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.|Plays a role in the Agrobacterium-mediated plant transformation via its interaction with VirB2; the major component of the T-pilus.
HIP39_ARATH,Cluster-37893.0,7,Probable heavy-metal-binding protein.
THA1_ARATH,Cluster-43831.0,6,Threonine aldolase involved in threonine degradation to glycine. May play a role in the removal of L-allo-threonine.
PME31_ARATH,Cluster-35370.0,4,Acts in the modification of cell walls via demethylesterification of cell wall pectin (By similarity). Acts in a blockwise manner; resulting in a cell wall rigidification.
XYL2_MEDSV|XYL1_MEDSV,Cluster-3965.0,4,A bifunctional beta-xylosidase/alpha-L-arabinosidase; exo-enzyme that acts synergistically with endohydrolases. Releases xylose and arabinose from cell walls.|A bifunctional beta-xylosidase/alpha-L-arabinosidase; exo-enzyme that acts synergistically with endohydrolases. Releases xylose and arabinose from cell walls. Does not cleave xylan from oat spelts although xylan from oat spelts was degraded to xylose when this enzyme was used in combination with xylanase. Also releases xylose and arabinose from aryl glycosides; xylo-oligosaccharides; arabinan from sugar beet and arabino-oligosaccharides; arabinan from sugar beet and arabinoxylan from wheat.
LRK10_WHEAT|AT21A_ARATH,Cluster-42733.0,1,Involved in resistance response to the pathogenic fungus Alternaria brassicicola.|Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation.
CAMT3_ARATH,Cluster-29586.0,4,Methylates caffeoyl-CoA to feruloyl-CoA and 5-hydroxyferuloyl-CoA to sinapoyl-CoA. Plays a role in the synthesis of feruloylated polysaccharides. Involved in the reinforcement of the plant cell wall. Also involved in the responding to wounding or pathogen challenge by the increased formation of cell wall-bound ferulic acid polymers.
PSBS_SPIOL,Cluster-55294.2,2,Seems to be involved in non-photochemical quenching; a process maintains the balance between dissipation and utilization of light energy to minimize generation of oxidizing molecules; thereby protecting the plant against photo-oxidative damage.
C77A3_SOYBN,Cluster-3030.1,2,NA
FBK22_ARATH,Cluster-51214.0,6,NA
TRL11_ORYSJ,Cluster-55036.0,3,Probable thiol-disulfide oxidoreductase that may participate in various redox reactions.
Y2416_ARATH,Cluster-40526.0,4,NA
RAA1F_ARATH,Cluster-49811.0,4,Intracellular vesicle trafficking and protein transport.
ACR11_ARATH,Cluster-51492.0,1,May be involved in feedback regulation of amino acid metabolism. May be involved in the regulation of glutamine metabolism.
COBL7_ARATH,Cluster-7830.0,5,Involved in determining the orientation of cell expansion; probably by playing an important role in cellulose deposition. May act by recruiting cellulose synthesizing complexes to discrete positions on the cell surface.
14312_ARATH,Cluster-38402.0,4,Is associated with a DNA binding complex that binds to the G box; a well-characterized cis-acting DNA regulatory element found in plant genes.
CSA_ORYSJ,Cluster-2776.0,5,Transcription factor required for sugar partitioning from leaves to anthers during male reproductive development. Required for the production of functional pollen grains. Binds to the promoter of the anther-specific sugar transporter MST8 and regulates its expression. Regulates the expression of genes involved in sugar partitioning in flower; such as the sugar transporter SUT3; the invertase INV4; the UDP-glucose pyrophosphorylase UGP2 and the starch synthase WAXY.
PHT17_ARATH,Cluster-42504.0,4,High-affinity transporter for external inorganic phosphate.
PTRB_MORLA,Cluster-25002.0,5,Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues.
C7A52_PANGI|C7A15_VITVI,Cluster-44509.1,4,Catalyzes the carboxylation of beta-amyrin at the C-28 position to form oleanolic acid during ginsenoside biosynthesis; a class of tetracyclic triterpenoid saponins.|
AGL18_ARATH,Cluster-7900.1,5,Probable transcription factor involved in the negative regulation of flowering; probably through the photoperiodic pathway. Prevents premature flowering. Downstream regulator of a subset of the MIKC* MADS-controlled genes required during pollen maturation.
EF2_ARATH,Cluster-29989.0,4,Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step; the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites; respectively. Catalyzes the coordinated movement of the two tRNA molecules; the mRNA and conformational changes in the ribosome (By similarity). Involved in cold responses leading to freezing tolerance via the induction of cold-responsive genes (PubMed:9401119; PubMed:12032361).
PMTI_ARATH,Cluster-44704.0,4,NA
ZWIP4_ARATH,Cluster-41485.0,6,Probable transcriptional regulator.
GRXC9_ARATH,Cluster-36564.0,3,Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
CB4A_ARATH|CB4B_ARATH,Cluster-34164.0,2,The light-harvesting complex (LHC) functions as a light receptor; it captures and delivers excitation energy to photosystems with which it is closely associated.|
ERF81_ARATH,Cluster-41734.1,5,Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways. Transcription factor that binds to the GCC-box pathogenesis-related promoter element. Acts as a transcriptional inhibitor and may regulate other AtERFs.
C71DA_SOYBN,Cluster-39352.0,4,NA
TET8_ARATH,Cluster-47859.0,4,May be involved in the regulation of cell differentiation.
DLO2_ARATH|FL3H3_ORYSJ,Cluster-34369.0,1,Converts salicylic acid (SA) to 2;3-dihydroxybenzoic acid (2;3-DHBA) (By similarity). Negative regulator of defense against Hyaloperonospora arabidopsidis (PubMed:25376907).|(Microbial infection) Confers susceptibility to the downy mildew pathogen Hyaloperonospora arabidopsidis.|Catalyzes the 3-beta-hydroxylation of 2S-flavanones to 2R;3R-dihydroflavonols which are intermediates in the biosynthesis of flavonols; anthocyanidins; catechins and proanthocyanidins in plants (PubMed:18413994; PubMed:18726614). Converts (2S)-eriodictyol to (+)-taxifolin and (2S)-naringenin to (+)-(2R/3R)-dihydrokaempferol in vitro (PubMed:18413994).
C734A_ARATH,Cluster-39177.0,6,Cytochrome P450 involved in brassinosteroids (BRs) inactivation and regulation of BRs homeostasis. Inactivates the BRs castasterone and brassinolide through carbon 26 hydroxylation. Acts in association with CYP72C1 to inactivate BRs and modulate photomorphogenesis.
CIPK5_ORYSJ,Cluster-28430.0,4,CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner.
TPS1_PHYDL|TPS5_PHYDL,Cluster-33169.0,4,Sesquiterpene synthase converting farnesyl diphosphate to alpha copaene and delta-cadinene as the major products.|Sesquiterpene synthase converting farnesyl diphosphate to bicyclogermacrene as the major product.
MSL7_ARATH|MSL8_ARATH,Cluster-31349.0,5,Mechanosensitive channel that opens in response to stretch forces in the membrane lipid bilayer.|Mechanosensitive channel that opens in response to stretch forces in the membrane lipid bilayer. Exhibits a 6.3-fold preference for chloride over sodium. Regulates osmotic forces during pollen hydration and germination.
PDR1_TOBAC|PDR1_NICPL,Cluster-30995.0,4,|Excretes secondary metabolites such as terpenes. Involved in both constitutive and jasmonic acid-dependent induced defense. Confers some resistance to sclareol and B.cinerea.
TRXH2_ARATH,Cluster-32903.2,4,Thiol-disulfide oxidoreductase probably involved in the redox regulation of a number of cytosolic enzymes. Possesses insulin disulfide bonds reducing activity.
FDH_SOLTU,Cluster-48191.0,1,Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide (PubMed:8278546). Involved in the cell stress response. Involved in formate-dependent oxygen uptake coupled to ATP synthesis (PubMed:9490763).
TIC32_PEA,Cluster-33187.0,1,Involved in protein precursor import into chloroplasts. Part of the redox regulon consisting of TIC32; TIC 55 and TIC62. Has a NADPH-dependent dehydrogenase activity; but only after preincubation with lipids.
ARFC_ARATH,Cluster-37842.4,1,Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Could act as transcriptional activator or repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Involved in the establishment or elaboration of tissue patterning during gynoecial development.
HAT22_ARATH|HAT9_ARATH,Cluster-39322.0,4,Probable transcription factor.|Probable transcription factor.
GDL67_ARATH|GDL79_ARATH,Cluster-47810.0,1,|
C71DA_SOYBN,Cluster-30616.0,6,NA
BGL12_ORYSI|BGL12_ORYSJ,Cluster-43244.2,1,|Hydrolyzes p-nitrophenyl beta-D-glucoside; p-nitrophenyl beta-D-galactoside; p-nitrophenyl beta-D-xyloside; p-nitrophenyl beta-D-fucoside; p-nitrophenyl beta-L-arabinoside; cello-oligosaccharides and laminaribiose.
YLS3_ARATH,Cluster-49050.0,1,NA
SDL5A_SOYBN|DRP1A_ARATH,Cluster-38699.0,4,Microtubule-associated force-producing protein.|Microtubule-associated force-producing protein that is targeted to the forming cell plate during cytokinesis. Plays also a major role in plasma membrane maintenance and cell wall integrity with implications in vesicular trafficking; polar cell expansion; vascular formation; and other aspects of plant growth and development. Has a GTPase activity.
Y3475_ARATH|EFR_ARATH,Cluster-31509.2,1,|
GPT2_ARATH,Cluster-50288.0,5,NA
HQGT_RAUSE,Cluster-37290.0,1,Broad spectrum multifunctional glucosyltransferase. In addition to hydroquinone it accept at least 45 natural and synthetic phenols as well as two cinnamyl alcohols as substrates. Hydroquinone was however the best substrate. In contrast to this broad acceptor substrate specificity; only pyrimidine nucleotide activated glucose is tolerated as a donor substrate.
PDR3_TOBAC,Cluster-49771.1,4,May be a general defense protein.
SGR_CAPAN,Cluster-55703.2,4,Required to trigger chlorophyll degradation during leaf senescence and fruit ripening.
RSS3_ORYSJ,Cluster-52973.0,6,NA
GUN8_ARATH,Cluster-39391.0,2,NA
AO1_ARATH,Cluster-50460.0,3,Oxidizes preferentially the aliphatic diamine putrescine with production of the corresponding aldehyde; ammonia and hydrogen peroxide. May be involved in the regulation of developmental programmed cell death (PCD) in both vascular tissue and the root cap (PubMed:9681017). Required for jasmonic acid-(MeJA) mediated early protoxylem differentiation associated with putrescine levels reduction and H(2)O(2) accumulation in roots (PubMed:25883242).
PYRG2_XENLA|PYRG_DICDI,Cluster-57576.0,7,Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides.|Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.
PXL2C_ARATH,Cluster-48697.0,3,May regulate positively ERK1/2 signaling and AKT1 activation leading to HIF1A up-regulation with an increased expression of glycolysis genes and enhanced glycolysis.
DHEB_NICPL,Cluster-47833.0,4,NA
RLGP1_ORYSJ|TLPH_ARATH,Cluster-39298.0,4,May play an important role in plant growth and development.|
MLP28_ARATH,Cluster-20489.0,1,Can bind steroids (in vitro); and may also bind other types of hydrophobic ligands.
4OMT2_PAPSO,Cluster-22041.1,2,Involved in the biosynthesis of benzylisoquinoline alkaloids (PubMed:16034588; PubMed:22725256; PubMed:23738019). Catalyzes the transfer of the methyl group to the 4'-hydroxyl group of 3'-hydroxy-N-methylcoclaurine to form reticuline (PubMed:16034588). Can also use laudanosoline and; with a lower activity; 6-O-methylnorlaudanosoline and norlaudanosoline as substrates (PubMed:16034588). Also involved in the papaverine biosynthesis (PubMed:22725256; PubMed:23738019).
RADL6_ARATH,Cluster-36270.0,4,Probable transcription factor.
RADL3_ARATH,Cluster-41744.0,4,Probable transcription factor.
IF2AH_ARATH,Cluster-2195.0,5,Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit; followed by mRNA binding to form a 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation; the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
B2_DAUCA,Cluster-38657.0,5,Binds double-strand RNA (dsRNA) with high affinity. Suppresses the host RNA silencing-based antiviral response.
FB322_ARATH,Cluster-33037.0,5,NA
CUL1_ARATH,Cluster-43279.0,3,Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Regulator of mitotic processes which plays a role during gametogenesis and embryogenesis. Together with SKP1; RBX1 and a F-box protein; it forms a SCF complex. The functional specificity of this complex depends of the type of F-box protein. SCF(UFO) is implicated in floral organ development. SCF(TIR1) is involved in auxin signaling pathway. SCF(COI1) regulates responses to jasmonates. SCF(EID1) and SCF(AFR) are implicated in phytochrome A light signaling. SCF(ADO1/ZTL); SCF(ADO2/LKP2); SCF(ADO3/FKF1) are related to the circadian clock. SCF(ORE9) seems to be involved in senescence. SCF(EBF1/EBF2) may regulate ethylene signaling.
ERF61_ARATH,Cluster-17828.0,5,Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways.
RBK1_ARATH,Cluster-57081.0,4,Catalyzes the phosphorylation of ribose 1;5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).
YSL7_ARATH,Cluster-32707.0,4,May be involved in the transport of nicotianamine-chelated metals.
PP240_ARATH,Cluster-40531.0,5,May play a role in embryogenesis.
LOR17_ARATH|LOR8_ARATH,Cluster-45958.0,5,Might be related to the phospholipid scramblase and tubby-like superfamily of membrane tethered transcription factors.|Might be related to the phospholipid scramblase and tubby-like superfamily of membrane tethered transcription factors.
FDP_ARATH|AI5L2_ARATH,Cluster-57112.0,5,Transcription factor required for the transition to flowering promoted by FT.|Binds to the embryo specification element and the ABA-responsive element (ABRE) of the Dc3 gene promoter. Could participate in abscisic acid-regulated gene expression during seed development.
FIMB5_ARATH,Cluster-35197.0,5,Cross-links actin filaments (F-actin) in a calcium independent manner. Induces the formation of actin bundles. Stabilizes and prevents F-actin depolymerization mediated by latrunculin B (LatB).
PBL28_ARATH,Cluster-55233.0,4,May be involved in plant defense signaling.
PER12_ARATH,Cluster-53657.0,4,Removal of H(2)O(2); oxidation of toxic reductants; biosynthesis and degradation of lignin; suberization; auxin catabolism; response to environmental stresses such as wounding; pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.|Exhibits a Ca(2+)-pectate binding affinity which could be interpreted in vivo as a specificity to interact with the pectic structure of the cell wall.
PER12_ARATH,Cluster-53657.5,4,Removal of H(2)O(2); oxidation of toxic reductants; biosynthesis and degradation of lignin; suberization; auxin catabolism; response to environmental stresses such as wounding; pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.|Exhibits a Ca(2+)-pectate binding affinity which could be interpreted in vivo as a specificity to interact with the pectic structure of the cell wall.
BZP44_ARATH,Cluster-48111.0,5,Transcription factor that binds to the DNA G-box motif 5'-CACGTG-3' of MAN7 promoter. Involved in the positive regulation of seed germination through MAN7 gene activation. MAN7 is required for both; loosening of the micropylar endosperm; and rupture of the seed coat in germinating seeds.
CP41A_ARATH,Cluster-23467.0,2,Binds and cleaves RNA; particularly in stem-loops. Associates with pre-ribosomal particles in chloroplasts; and participates in chloroplast ribosomal RNA metabolism; probably during the final steps of 23S rRNA maturation. May enhance transcription by the plastid-encoded polymerase and translation in plastid via the stabilization of ribosome assembly intermediates. Required for chloroplast integrity. Involved in the regulation of the circadian system.
GDL79_ARATH,Cluster-43086.0,5,NA
SBP1_ANTMA,Cluster-24089.0,5,Probable transcriptional factor. Binds to the promoter of the SQUAMOSA gene.
GEDH1_OCIBA,Cluster-32808.0,3,Involved in the production of citral; a mixture of geranial and neral with a strong lemony scent. Reversibly oxidizes geraniol and nerol in equal efficiency. Also active; although at a lower efficiency; with cinnamyl alcohol.
10HGO_CATRO,Cluster-24712.10,7,NA
UFC_ARATH,Cluster-29162.0,5,Part of a three-gene cluster containing FLC; UFC and DFC; which is coordinately regulated in response to vernalization. Also regulated by FLX.
NCL1_ORYSJ|NCL_ARATH,Cluster-38073.0,1,May function as a sodium/calcium exchanger (NCX) and participate in the maintenance of calcium homeostasis. May play a role abiotic stress responses.|Possesses sodium/calcium exchanger (NCX) activity when expressed in a heterologous mammalian CHO-K1 cell system (PubMed:23148213). Does not possess cation/proton exchanger (CAX) or sodium/proton (NHX) activity when expressed in a heterologous yeast cell system. Has the ability to bind calcium in vitro. Participates in the maintenance of calcium homeostasis (PubMed:23148213; PubMed:26296956). May play a role in auxin response; diurnal rhythm and flowering time (PubMed:26296956). Involved in salt stress response (PubMed:23148213).
ADF5_ARATH,Cluster-54804.0,4,Actin-depolymerizing protein. Severs actin filaments (F-actin) and binds to actin monomers.
CSLG3_ARATH,Cluster-26727.0,2,Thought to be a Golgi-localized beta-glycan synthase that polymerize the backbones of noncellulosic polysaccharides (hemicelluloses) of plant cell wall.
PLP6_ARATH,Cluster-44361.0,5,Possesses non-specific lipolytic acyl hydrolase (LAH) activity. Hydrolyzes phospholipids as well as galactolipids. May play a role in disease resistance.
KAO1_ARATH,Cluster-52563.0,5,Catalyzes three successive oxidations of ent-kaurenoic acid giving gibberellin 12 (GA12); a key step in gibberellins (GAs) biosynthesis. GAs; which are involved many processes; including stem elongation; play a central role in plant development.
LSH4_ARATH|LSH6_ARATH,Cluster-23486.0,5,Probable transcription regulator that acts as a developmental regulator by promoting cell growth in response to light (By similarity). May suppress organ differentiation in the boundary region.|Probable transcription regulator that acts as a developmental regulator by promoting cell growth in response to light.
PUX2_ARATH,Cluster-30898.0,6,Facilitates the interaction of SYP31 and CDC48A; thereby regulating an CDC48A membrane-associated function (Ref.8). Appears to act as a negative regulator mediating the powdery mildew-plant interaction (PubMed:19176722; PubMed:23301616).
DJB13_MOUSE|DNJB4_PONAB,Cluster-56156.0,1,Plays a role in the formation of the central complex of ciliary and flagellar axonemes.|Probable chaperone. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro).
XTH32_ARATH,Cluster-45501.1,2,Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers; an essential constituent of the primary cell wall; and thereby participates in cell wall construction of growing tissues.
XTH32_ARATH,Cluster-45501.0,2,Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers; an essential constituent of the primary cell wall; and thereby participates in cell wall construction of growing tissues.
INV1_DAUCA,Cluster-50870.0,7,NA
AB22G_ARATH,Cluster-56532.0,1,NA
AB22G_ARATH,Cluster-24068.0,1,NA
AB22G_ARATH,Cluster-55230.3,1,NA
Y5848_ARATH,Cluster-9995.2,2,Binds to DNA and alters its conformation. May be involved in regulation of gene expression; nucleoid organization and DNA protection.
PLY15_ARATH,Cluster-32677.5,5,NA
OLEO1_ARATH,Cluster-25113.0,2,May have a structural role to stabilize the lipid body during desiccation of the seed by preventing coalescence of the oil. Probably interacts with both lipid and phospholipid moieties of lipid bodies. May also provide recognition signals for specific lipase anchorage in lipolysis during seedling growth.
YAB5_ARATH,Cluster-48539.0,1,NA
NAC26_ARATH|NAC7_ARATH,Cluster-41606.0,4,Transcription activator that binds to the secondary wall NAC binding element (SNBE); 5'-(T/A)NN(C/T)(T/C/G)TNNNNNNNA(A/C)GN(A/C/T)(A/T)-3'; in the promoter of target genes (By similarity). Involved in xylem formation by promoting the expression of secondary wall-associated transcription factors and of genes involved in secondary wall biosynthesis and programmed cell death; genes driven by the secondary wall NAC binding element (SNBE). Triggers thickening of secondary walls (PubMed:25148240).|
Y4729_ARATH|SD11_ARATH,Cluster-8747.0,2,|Involved in the regulation of cellular expansion and differentiation.
PARP3_SOYBN|PARP3_MEDTR,Cluster-17625.0,5,Involved in the base excision repair (BER) pathway; by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.|Involved in the base excision repair (BER) pathway; by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
BH025_ARATH,Cluster-56834.0,1,NA
CLE16_ARATH,Cluster-47252.0,2,Extracellular signal peptide that regulates cell fate. Represses root apical meristem maintenance.
ACA11_ARATH,Cluster-26300.0,4,This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol out of the cell or into organelles.
86A22_PETHY,Cluster-14681.1,4,Fatty acyl-CoA omega-hydroxylase essential for the production of omega-hydroxy fatty acids and the biosynthesis of triacylglycerol-/diacylglycerol-based estolide polyesters in the stigma. Substrate preference is 16:0-CoA > 18:1-CoA > 18:0-CoA.
PIP27_ARATH,Cluster-27024.0,5,Water channel required to facilitate the transport of water across cell membrane. May be involved in the osmoregulation in plants under high osmotic stress such as under a high salt condition.
PIP27_ARATH,Cluster-27024.3,5,Water channel required to facilitate the transport of water across cell membrane. May be involved in the osmoregulation in plants under high osmotic stress such as under a high salt condition.
LAT52_SOLLC,Cluster-49377.0,4,May play a role during germination or early tube growth.
LAT52_SOLLC,Cluster-30770.0,4,May play a role during germination or early tube growth.
EXPA1_ARATH,Cluster-53173.0,4,NA
FLO_ANTMA,Cluster-23362.0,2,NA
PDC2_TOBAC,Cluster-20205.0,7,NA
PMA9_ARATH|PMA6_ARATH,Cluster-45293.0,5,The plasma membrane H(+) ATPase of plants and fungi generates a proton gradient that drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.|
CDF1_ARATH,Cluster-50133.0,1,Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence. A flanking TGT sequence contributes to the specificity of binding. Regulates a photoperiodic flowering response. Transcriptional repressor of 'CONSTANS' expression. The DNA-binding ability is not modulated by 'GIGANTEA' but the stability of CDF1 is controlled by the proteasome-dependent pathway. Ubiquitinated by the SCF(ADO3) E3 ubiquitin ligase complex. Binds to the FT promoter in the morning.
WAKLQ_ARATH,Cluster-53137.0,4,Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component.
EF114_ARATH,Cluster-40138.0,7,Transcriptional regulator of cell proliferation and axillary bud outgrowth. Involved in maintaining the structure of the shoot apical meristem as well as plastochron and phyllotaxy. Activates several genes involved in cell cycle regulation and dormancy breaking; including CYCD3-3; DPA; and BARD1. Strongly down-regulates DRM1; DRMH1; MARD1 and several genes encoding different types of cell wall-remodeling proteins.
PAE11_ARATH,Cluster-53434.0,4,Hydrolyzes acetyl esters in homogalacturonan regions of pectin. In type I primary cell wall; galacturonic acid residues of pectin can be acetylated at the O-2 and O-3 positions. Decreasing the degree of acetylation of pectin gels in vitro alters their physical properties.
GSTUI_ARATH,Cluster-55736.3,2,May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.
GSTUI_ARATH,Cluster-55736.0,1,May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.
U86A1_ARATH,Cluster-57407.0,6,Possesses low quercetin 3-O-glucosyltransferase; 7-O-glucosyltransferase; 3'-O-glucosyltransferase and 4'-O-glucosyltransferase activities in vitro.
ZWIP2_ARATH,Cluster-51020.0,2,Transcriptional regulator required for normal differentiation of the ovary transmitting tract cells and pollen tube growth. In Arabidopsis; the transmitting tract facilitates the transport of pollen tubes to the ovules for fertilization (PubMed:17600712). May play a role in the regulation of AGL8/FUL; which is required for normal pattern of cell division; expansion and differentiation during morphogenesis of the silique (PubMed:23515580). Plays a role in replum development by the activation of the homeobox protein KNAT1 (PubMed:25039392).
ZWIP2_ARATH,Cluster-51020.6,2,Transcriptional regulator required for normal differentiation of the ovary transmitting tract cells and pollen tube growth. In Arabidopsis; the transmitting tract facilitates the transport of pollen tubes to the ovules for fertilization (PubMed:17600712). May play a role in the regulation of AGL8/FUL; which is required for normal pattern of cell division; expansion and differentiation during morphogenesis of the silique (PubMed:23515580). Plays a role in replum development by the activation of the homeobox protein KNAT1 (PubMed:25039392).
ZWIP2_ARATH,Cluster-53656.0,4,Transcriptional regulator required for normal differentiation of the ovary transmitting tract cells and pollen tube growth. In Arabidopsis; the transmitting tract facilitates the transport of pollen tubes to the ovules for fertilization (PubMed:17600712). May play a role in the regulation of AGL8/FUL; which is required for normal pattern of cell division; expansion and differentiation during morphogenesis of the silique (PubMed:23515580). Plays a role in replum development by the activation of the homeobox protein KNAT1 (PubMed:25039392).
AGAL1_ARATH,Cluster-35181.0,2,May regulate leaf (and possibly other organ) development by functioning in cell wall loosening and cell wall expansion.
HST_TOBAC|RAS_PLESU,Cluster-2964.2,5,Acyltransferase involved in the biosynthesis of lignin. The affinity for shikimate as acceptor is 100-fold higher than for quinate. The most efficient donors are caffeoyl-CoA > p-coumaroyl-CoA > feruloyl-CoA >> sinapoyl-CoA.|Involved in the biosynthesis of rosmarinic acid; a compound with antiviral; antimicrobial and anti-inflammatory activities. Can use 4-coumaroyl- and caffeoyl-CoA as hydroxycinnamoyl donors and 4-Hydroxyphenyllactate and 3.4-Dihydroxyphenyllactate; but not shikimate or quinate; as hydroxycinnamoyl acceptors. Can also putatively catalyze amide formation with D-amino acids as acceptors.
CCX3_ARATH,Cluster-55425.0,6,Endomembrane-localized H(+)-dependent K(+) and Na(+) transporter. May have a function associated with the pollen vacuole during tube elongation and polarized top growth.
AHK4_ARATH,Cluster-49171.0,2,Cytokinins (CK) receptor related to bacterial two-component regulators. Binds also the synthetic urea-type cytokinin thiadiazuron; a potent defoliant and herbicide. Functions as a histidine kinase and transmits the stress signal to a downstream MAPK cascade. This protein undergoes an ATP-dependent autophosphorylation at a conserved histidine residue in the kinase core; and a phosphoryl group is then transferred to a conserved aspartate residue in the receiver domain. In the presence of cytokinin; feeds phosphate to phosphorelay-integrating histidine phosphotransfer protein (HPt) and activates subsequent cascade. In the absence of cytokinin; removes phosphate from HPt proteins; decreasing the system phosphoload. Involved in meristems establishment in seedlings. Acts as a redundant negative regulator of drought and salt stress responses; and abscisic acid (ABA) signaling in a cytokinin-dependent manner. Required to set vascular asymmetric cell divisions that establish phloem and procambium cell lines. Redundant positive regulator of cytokinin signaling that regulates many developmental processes including seed germination; cell division; seed size; chlorophyll retention during leaf senescence; root repression and shoot promotion. Can interact with isoprenoid-type cytokinins trans-zeatin (tZ and tZR); isopentenyladenine (iP); and isopentenyladenosine (iPR); the meta hydroxylated derivative of benzyladenine m-topolin; buta-2;3-dienyladenine (HA-8); penta-2;3-dienyladenine (HA-1); 4-methyl-penta-2;3-dienyladenine (HA-10); 4-hydroxy-2-butynyladenine (RM1); 2-butynyladenine (RM6); and to a lower extent; with cis-zeatin (cZ); zeatin riboside and dihydrozeatin (DZ). Together with AHK3; involved in the cytokinin-dependent responses to Pi starvation and sucrose stresses. Required for the formation of auxin-transporting vascular tissues in the hypocotyl; and primary and lateral roots; but not in adventitious roots; thus leading to auxin basipetal transport that regulates root development and branching. Involved in alkamides (e.g. N-isobutyl decanamide) and N-acylethanolamides (NAE) signaling that control meristematic activity and differentiation processes during plant development. Prevents the uptake of sulfate by mediating cytokinin-dependent down-regulation of high-affinity sulfate transporters (e.g. SULTR1;1 and SULTR1;2) expression in roots. Together with AHK2; required for growth and reproduction promotion stimulated by the endophytic fungus Piriformospora indica in a trans-zeatin-dependent manner. Required to trigger the phytotoxic effect of the snapdragon (Antirrhinum majus) flowers volatile organic compound (VOC) methyl benzoate (MB). Plays a role in the cytokinin-mediated repression of the iron uptake pathway.
FAD2_VERFO|FAD2B_CALOF,Cluster-50016.2,5,Catalyzes the desaturation of oleic acid (18:1(9Z)) to linoleic acid (18:2(9Z;12Z)).|Converts linoleic acid into a conjugated octadecatrienoic acid; probably calendic acid.
PER64_ARATH,Cluster-51952.0,1,Removal of H(2)O(2); oxidation of toxic reductants; biosynthesis and degradation of lignin; suberization; auxin catabolism; response to environmental stresses such as wounding; pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.
GSO1_ARATH,Cluster-37061.0,7,Together with GSO2; receptor-like serine/threonine-kinase required during the development of the epidermal surface in embryos and cotyledons (PubMed:18088309). In coordination with GSO2; regulates root growth through control of cell division and cell fate specification. Controls seedling root growth by modulating sucrose response after germination (PubMed:24123341). Receptor of the peptide hormones CIF1 and CIF2 required for contiguous Casparian strip diffusion barrier formation in roots (PubMed:28104889). Required for localizing CASP proteins into the Casparian strip following an uninterrupted; ring-like domain; to trigger endodermal differentiation and thus regulate potassium ion (K) homeostasis. Involved in the maintenance of water transport and root pressure. May also be involved in the regulation of suberin accumulation in the endodermis (PubMed:25233277).
REM16_ARATH,Cluster-53704.0,2,NA
BGLC_OLEEU|BGL16_ORYSJ,Cluster-19860.15,2,Major beta-glucosidase activating oleuropein into a potent protein cross-linking agent (PubMed:25697790; PubMed:28483880). No activity with rutin; luteolin or p-nitrophenyl-beta-glucopyranoside as substrates (PubMed:25697790).|
DOGL3_ARATH,Cluster-27642.1,3,NA
SAU32_ARATH,Cluster-25138.0,7,May play a role in the apical hook development (Ref.6).
ROGF8_ARATH,Cluster-36372.0,4,NA
ADO3_ARATH,Cluster-42966.1,4,Component of an E3 ubiquitin ligase complex that plays a central role in blue light-dependent circadian cycles. Acts as a blue light photoreceptor; due to the presence of FMN; that mediates light-regulated protein degradation of critical clock components by targeting them to the proteasome complex. The SCF(ADO3) E3 ubiquitin ligase complex is involved in the regulation of circadian clock-dependent processes including transition to flowering time; hypocotyl elongation; cotyledons and leaf movement rhythms. Forms a complex with 'GIGANTEA' (GI) to regulate 'CONSTANS' (CO) expression. Promotes CO expression during the light period of long days by decreasing the stability of CDF1 and CDF2 and by interacting directly with the CO protein and stabilizing it. ADO3 function is mainly GI dependent. Does not act as a regulator of CDF1 transcription. The interactions of ADO1/ZTL and ADO2 with ADO3 prevent its interaction with CDF1.
WAVH1_ARATH|WAVH2_ARATH,Cluster-48742.0,2,E3 ubiquitin-protein ligase involved in the regulation of root growth. Acts as positive regulator of root gravitropism. Possesses E3 protein ligase activity in vitro.|Probable E3 ubiquitin-protein ligase involved in the regulation of root growth. Acts as positive regulator of root gravitropism.
FBK23_ARATH,Cluster-51590.0,3,NA
PPR85_ARATH,Cluster-35034.0,3,NA
MT1_ERYGU,Cluster-42265.0,4,Metallothioneins have a high content of cysteine residues that bind various heavy metals.
HIP22_ARATH,Cluster-56469.0,5,Heavy-metal-binding protein. Binds cadmium. May be involved in cadmium transport and play a role in cadmium detoxification.
CSLD1_ARATH|CTF18_XENLA,Cluster-47445.0,5,Thought to be a Golgi-localized beta-glycan synthase that polymerize the backbones of noncellulosic polysaccharides (hemicelluloses) of plant cell wall.|Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear antigen loader complexes; CTF18-replication factor C (CTF18-RFC); which consists of ctf18; ctf8; dcc1; rfc2; rfc3; rfc4 and rfc5. The CTF18-RFC complex binds to single-stranded and primed DNAs and has weak ATPase activity that is stimulated by the presence of primed DNA; replication protein A (RPA) and by proliferating cell nuclear antigen (pcna). The CTF18-RFC complex catalyzes the ATP-dependent loading of pcna onto primed and gapped DNA.
PPA22_ARATH,Cluster-38200.1,1,NA
DICH_ANTMA,Cluster-44827.0,6,Transcription regulator involved in the dorsovental asymmetry of flowers. Promotes dorsal identity.
Y231_RICCO,Cluster-37541.0,4,NA
RACD_PYRHO|RACX_BACSU,Cluster-46859.0,4,|Probable aspartate or glutamate racemase involved in peptidoglycan modification during cortex synthesis.
LSH4_ARATH|LSH3_ARATH,Cluster-44262.0,3,Probable transcription regulator that acts as a developmental regulator by promoting cell growth in response to light (By similarity). May suppress organ differentiation in the boundary region.|Probable transcription regulator that acts as a developmental regulator by promoting cell growth in response to light (By similarity). Required for the maintenance of the shoot apical meristem and for the formation of lateral organs. Promotes petal formation and growth; but may suppress organ differentiation in the boundary region.
LSH10_ARATH,Cluster-11524.0,2,NA
U74F2_ARATH|U74E2_ARATH,Cluster-32203.2,1,Glycosyltransferase that glucosylates benzoic acid and derivatives. Substrate preference is benzoic acid > salicylic acid (SA) > 3-hydroxybenzoic acid > 4-hydroxybenzoic acid. Catalyzes the formation of both SA 2-O-beta-D-glucoside (SAG) and SA glucose ester (SGE). Has high affinity for the tryptophan precursor anthranilate. Catalyzes the formation of anthranilate glucose ester. Is the major source of this activity in the plant.|
BGAL3_ARATH,Cluster-51249.0,1,Preferentially hydrolyzes para-nitrophenyl-beta-D-galactoside. Can hydrolyze para-nitrophenyl-beta-D-fucoside with 5 time less efficiency.
BGAL3_ARATH,Cluster-51249.1,1,Preferentially hydrolyzes para-nitrophenyl-beta-D-galactoside. Can hydrolyze para-nitrophenyl-beta-D-fucoside with 5 time less efficiency.
OPT5_ARATH,Cluster-25264.0,1,Involved in the translocation of tetra- and pentapeptides across the cellular membrane in an energy-dependent manner.
RAA5A_ARATH,Cluster-34463.1,1,NA
AHP1_ARATH,Cluster-631.1,5,Functions as two-component phosphorelay mediators between cytokinin sensor histidine kinases and response regulators (B-type ARRs). Plays an important role in propagating cytokinin signal transduction through the multistep His-to-Asp phosphorelay.
AHP1_ARATH,Cluster-631.0,5,Functions as two-component phosphorelay mediators between cytokinin sensor histidine kinases and response regulators (B-type ARRs). Plays an important role in propagating cytokinin signal transduction through the multistep His-to-Asp phosphorelay.
MCA1_ARATH,Cluster-49117.0,4,Cysteine protease that cleaves specifically after arginine or lysine residues. Does not cleave caspase-specific substrates. Acts as a positive regulator of cell death. Required for both oxidative stress cell death response and hypersensitive cell death response mediated by immune response.
AVT1J_ARATH,Cluster-46846.0,1,NA
CB2D_SOLLC|CB21_RAPSA,Cluster-1406.25,2,The light-harvesting complex (LHC) functions as a light receptor; it captures and delivers excitation energy to photosystems with which it is closely associated.|The light-harvesting complex (LHC) functions as a light receptor; it captures and delivers excitation energy to photosystems with which it is closely associated.
GDL66_ARATH,Cluster-53340.0,4,NA
CK1_ARATH,Cluster-31912.1,4,NA
PMI11_ARATH,Cluster-55151.1,7,Pectin methylesterase (PME) inhibitor involved in the maintenance of cell wall integrity in response to necrotrophic pathogens. Modulates PME activity and pectin methylesterification during infection by Botrytis cinerea and contributes to resistance against the pathogen.
ACR4_ARATH,Cluster-35384.0,5,May bind amino acids.
GLOX_VITPS,Cluster-44443.0,5,Catalyzes the oxidation of aldehydes to the corresponding carboxylate by coupling the reaction to the reduction of dioxygen to hydrogen peroxide. Substrates include glyoxal and other aldehydes (By similarity). Involved in disease resistance against the grapevine powdery mildew E.necator. Is sufficient to confer disease resistance to E.necator (PubMed:20512385; PubMed:23090239). Can produce hydrogen peroxide in response to E.necator infection; and this may directly play a role in the defense mechanism during plant-pathogen interactions (PubMed:23090239).
AP180_ARATH,Cluster-29882.0,5,Adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins; leading to their selection and concentration. Binding of AP180 to clathrin triskelia promotes their assembly into 70-90 nm coats cages.
AG_PANGI|AGL1_ARATH,Cluster-57088.0,5,Probable transcription factor involved in regulating genes that determines stamen and carpel development in wild-type flowers.|Probable transcription factor. Interacts genetically with TT16/AGL32 in a partially antagonistic manner during flower development. Is essential for the coordination of cell divisions in ovule; seed coat development and endosperm formation (PubMed:27776173).
PLY15_ARATH|PLY10_ARATH,Cluster-57078.1,1,|Susceptibility factor required for infection by most powdery mildews; but not by unrelated pathogens. Exact function not known; but clearly affects cell wall composition.
PLY15_ARATH|PLY10_ARATH,Cluster-57078.0,1,|Susceptibility factor required for infection by most powdery mildews; but not by unrelated pathogens. Exact function not known; but clearly affects cell wall composition.
SINA2_ARATH,Cluster-42778.0,5,E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. It probably triggers the ubiquitin-mediated degradation of different substrates (Probable). Mediates the proteasomal-dependent degradation of ATG6; a component of the autophagosome complex. Requires TRAF1A/MUSE14 and TRAF1B/MUSE13 to target ATG6 for ubiquitination and subsequent regulation of autophagosome assembly (PubMed:28351989).
Y1869_ARATH,Cluster-2422.0,5,NA
ORR26_ORYSJ,Cluster-37825.0,7,Transcriptional activator that binds specific DNA sequence. Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. May directly activate some type-A response regulators in response to cytokinins.
PBL26_ARATH|PBL25_ARATH,Cluster-31680.1,4,May be involved in plant defense signaling.|May be involved in plant defense signaling.
Y8219_ORYSJ,Cluster-51889.0,4,NA
ACD6_ARATH|Y5262_ARATH,Cluster-54530.0,4,Dose-dependent activator of the defense response against virulent pathogens; including bacteria; fungi and oomycetes; that acts in a positive feedback loop with the defense signal salicylic acid (SA) (PubMed:14507999; PubMed:20520716; PubMed:10488236; PubMed:16297071; PubMed:19144005). Regulates the salicylic acid (SA) signaling pathway leading to cell death and modulating cell fate (e.g. cell enlargement and/or cell division) (PubMed:14507999; PubMed:10488236; PubMed:11722764). In response to SA signaling; triggers the accumulation of FLS2 at the plasma membrane; thus priming defenses (PubMed:24923602). Involved in SA-dependent freezing signaling and tolerance (PubMed:19959255).|
FB248_ARATH,Cluster-57055.0,5,NA
ADHL1_ARATH|ADH1_ARATH,Cluster-32058.0,6,|
UGT9_GARJA,Cluster-30943.0,2,Glucosyltransferase catalyzing the beta 1-6 glucosylation of the sugar moiety of crocetin glucosyl esters to produce crocetin gentiobiosyl esters. Weak activity toward curcumin glucosides; but no activity with flavonoid glucosides; coumarin glucosides; 4-nitrophenyl glucoside or crocetin. Involved with UGT75L6 in sequential glycosylation of crocetin to crocin (bis(beta-D-gentiobiosyl) crocetin).
NAC42_ARATH,Cluster-55919.0,5,Transcription factor that binds to the 5'- RRYGCCGT-3' consensus core sequence. Central longevity regulator. Negative regulator of leaf senescence. Modulates cellular H(2)O(2) levels and enhances tolerance to various abiotic stresses through the regulation of DREB2A.
CB24_TOBAC,Cluster-20836.0,2,The light-harvesting complex (LHC) functions as a light receptor; it captures and delivers excitation energy to photosystems with which it is closely associated.
PSAL_ARATH,Cluster-48194.0,2,NA
ALDO4_ARATH,Cluster-33984.0,5,NA
TDT_ARATH,Cluster-33493.0,4,Putative carrier protein indirectly involved in the uptake of malate and fumarate to the vacuole; probably by regulating the energization across the tonoplast. Uptake of malate to vacuoles is inhibited by citrate and by the uncoupler carbonyl-cyanide m-chlorophenylhydrazone; but seems to be not affected by sodium. Critical for pH homeostasis.
CBL10_ARATH,Cluster-48976.0,7,NA
AAE_RAUSE,Cluster-45497.2,7,Deacetylates 17-O-acetylajmaline and 17-O-acetylnorajmaline; but is inactive toward other acetylated alkaloids.
DOF34_ARATH|DOF58_ARATH,Cluster-25266.0,5,|Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence.
DHAS_BACSU,Cluster-3513.0,5,Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
DHAS_BACSU,Cluster-3513.1,5,Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
WSD1_ARATH,Cluster-25163.2,5,Bifunctional wax ester synthase/diacylglycerol acyltransferase. Involved in cuticular wax biosynthesis.
WSD1_ARATH,Cluster-25163.1,5,Bifunctional wax ester synthase/diacylglycerol acyltransferase. Involved in cuticular wax biosynthesis.
WIN1_ARATH,Cluster-54620.0,1,Promotes cuticle formation by inducing the expression of enzymes involved in wax biosynthesis (PubMed:15070782; PubMed:15319479). Confers drought resistance (PubMed:15319479). Acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways.
SPG1_SCHPO,Cluster-31908.0,4,NA
EXPB2_ARATH|EXB15_ORYSJ,Cluster-39382.0,4,May cause loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found.|May cause loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found. May be required for rapid internodal elongation in deepwater rice during submergence.
SWT16_ORYSJ,Cluster-26969.1,1,Mediates both low-affinity uptake and efflux of sugar across the plasma membrane.
LHT2_ARATH|LHT1_ARATH,Cluster-5292.0,5,Amino acid-proton symporter. Transporter with a broad specificity for neutral and acidic amino acids. Basic amino acids are only marginally transported. Involved in import of amino acids into the tapetum cells for synthesis of compounds important for microspore structure.|Amino acid-proton symporter. Transporter with a broad specificity for histidine; lysine; glutamic acid; alanine; serine; proline and glycine. Involved in both apoplastic transport of amino acids in leaves and their uptake by roots.
INVB_ARATH,Cluster-41851.0,7,Invertase that cleaves sucrose into glucose and fructose.
RCE1_ARATH,Cluster-23285.0,4,Accepts the ubiquitin-like protein NEDD8/RUB1 from the ECR1-AXR1 E1 complex and catalyzes its covalent attachment to other proteins.
KASC1_ARATH,Cluster-43519.0,4,NA
KASC1_ARATH,Cluster-45715.0,4,NA
PNSB4_ARATH,Cluster-1460.2,2,NDH shuttles electrons from NAD(P)H:plastoquinone; via FMN and iron-sulfur (Fe-S) centers; to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation; and thus conserves the redox energy in a proton gradient.
PP151_ARATH,Cluster-47666.0,5,Promotes the splicing of group II introns in chloroplasts. Required for the splicing of intron 2 of plastid ycf3 transcripts; a factor required for the assembly of photosystem I (PSI). Involved in the splicing of several other group-IIa introns. May be involved in the splicing of precursor forms of trnL; trnG; trnI; and trnA. Required for the assembly of PSI and PSII.
P5CS_SOLLC|P5CS1_ORYSJ,Cluster-40554.0,7,P5CS plays a key role in proline biosynthesis; leading to osmoregulation in plants.|P5CS plays a key role in proline biosynthesis; leading to osmoregulation in plants. Involved in abiotic stress tolerance.
ADT1_SOLTU|ADT2_SOLTU,Cluster-26223.0,4,Catalyzes the exchange of ADP and ATP across the mitochondrial inner membrane.|Catalyzes the exchange of ADP and ATP across the mitochondrial inner membrane.
ZAT9_ARATH,Cluster-37209.0,4,Probable transcription factor that may be involved in stress responses.
SEC_ARATH|CYTB_HELAN,Cluster-23404.0,5,O-linked N-acetylglucosamine transferase (OGT) that mediates O-glycosylation of capsid protein (CP) of virus in case of infection by Plum pox virus. OGTs catalyze the addition of nucleotide-activated sugars directly onto the polypeptide through O-glycosidic linkage with the hydroxyl of serine or threonine. Probably acts by adding O-linked sugars to yet unknown proteins. Its OGT activity has been proved in vitro but not in vivo. Required with SPY for gamete and seed development.|Strong inhibitor of papain; ficin and cathepsin H; B and L.
SGO2_ARATH|SGO1_MAIZE,Cluster-41340.1,5,Dispensable for both meiotic and mitotic cell cycle progression (PubMed:24206843; PubMed:23884434). Required with SGO1 for full protection of centromeric cohesion during anaphase I (PubMed:24206843). Required to prevent precocious release of pericentromeric cohesins during meiosis (PubMed:24206843). Acts redundantly to SGO1 (PubMed:24506176).|Plays a central role in chromosome cohesion during meiosis I by preventing premature dissociation of cohesin complex from centromeres after prophase; when most of cohesin complex dissociates from chromosomes arms. Required for maintenance of centromeric cohesion before prophase II and correct segregation of chromatids during meiosis II. Has apparently no function in mitosis.
PP2B8_ARATH,Cluster-20188.1,5,NA
DTX24_ARATH,Cluster-27295.4,1,NA
GLGS_BRANA|GLGS_BETVU,Cluster-38115.4,5,This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor; ADP-glucose from Glc-1-P and ATP.|This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor; ADP-glucose from Glc-1-P and ATP.
DSP8_ARATH,Cluster-52985.1,3,May possess phosphatase activity.
SCP25_ARATH|SCP24_ARATH,Cluster-47140.0,4,Probable carboxypeptidase.|Active serine carboxypeptidase with broad substrate preference; including basic and hydrophilic groups. Processes a protein involved in an early event in the brassinosteroid signaling pathway.
BSP_BOSSE,Cluster-3848.0,5,Metalloprotease; digests gelatin and azocasein (in vitro).
DR100_ARATH,Cluster-48008.1,4,NA
PPR68_ARATH,Cluster-6963.2,2,NA
S17P_WHEAT|S17P_SPIOL,Cluster-37396.0,2,|
YSL1_ARATH|YSL3_ARATH,Cluster-26899.0,4,Involved in iron loading of the seeds. Acts probably as a transporter of iron- and metal-nicotianamine chelates.|May be involved in the lateral transport of nicotianamine-chelated metals in the vasculature.
BGLC_OLEEU,Cluster-19860.10,2,Major beta-glucosidase activating oleuropein into a potent protein cross-linking agent (PubMed:25697790; PubMed:28483880). No activity with rutin; luteolin or p-nitrophenyl-beta-glucopyranoside as substrates (PubMed:25697790).
RAC7_ARATH|PLST2_ARATH,Cluster-27758.8,5,|May be involved in the efflux of glucose towards the cytosol.
LIGV1_LIGVU,Cluster-55388.0,4,NA
SWT17_ARATH,Cluster-49011.0,2,Acts as a vacuolar hexose transporter (PubMed:25988582). Regulates fructose (Fru) homeostasis in leaves and roots by exporting/importing Fru through the tonoplast regarding metabolic demand (PubMed:23583552; PubMed:24381066).
LEA47_ARATH,Cluster-50834.0,4,LEA proteins are late embryonic proteins abundant in higher plant seed embryos. The function of those proteins is not known.
FDL25_ARATH,Cluster-2736.0,5,NA
NLTP2_TOBAC|NLTP2_BRANA,Cluster-47722.0,1,Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.|Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
CYSP_PEA,Cluster-18170.0,1,NA
TBB8_ARATH|TBB2_ORYSJ,Cluster-35944.3,3,Tubulin is the major constituent of microtubules. It binds two moles of GTP; one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.|Tubulin is the major constituent of microtubules. It binds two moles of GTP; one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
MYO11_ARATH|MYO9_ARATH,Cluster-53259.0,6,Myosin heavy chain that is required for the cell cycle-regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments; thereby transporting its cargo along polarized actin cables. Involved in trafficking of Golgi stacks; mitochondria and peroxisomes.|Myosin heavy chain that is required for the cell cycle-regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments; thereby transporting its cargo along polarized actin cables. Involved in trafficking of Golgi stacks and mitochondria.
Y3G1_ENCCU,Cluster-25666.0,3,NA
COPT5_ARATH,Cluster-38277.0,2,Involved in the transport of copper.
GLR32_ARATH,Cluster-42787.0,5,Glutamate-gated receptor that probably acts as non-selective cation channel. May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells. Could play a role in calcium unloading from xylem.
RBOHA_SOLTU,Cluster-29665.0,4,Calcium-dependent NADPH oxidase that generates superoxide. Involved in the rapid and transient phase I oxidative burst induced by pathogen infection.
C7A52_PANGI,Cluster-33077.0,4,Catalyzes the carboxylation of beta-amyrin at the C-28 position to form oleanolic acid during ginsenoside biosynthesis; a class of tetracyclic triterpenoid saponins.
NDB4_ARATH,Cluster-26957.0,4,Alternative NADH-ubiquinone oxidoreductase which catalyzes the oxidation of mitochondrial NADH does not translocate protons across the inner mitochondrial membrane (By similarity). NAD(P)H dehydrogenase; more efficient on NADH.
PPA17_ARATH,Cluster-39774.0,4,NA
PPA17_ARATH|PPA3_ARATH,Cluster-44044.0,4,|May dephosphorylate thiamine phosphates.
CONG1_LUPAN,Cluster-55605.3,4,Sulfur-rich seed storage protein that remains undegraded at germination.
IQD31_ARATH,Cluster-44175.0,6,Guanine nucleotide exchange factor for ARF1 and ARF6 (PubMed:24058294). Guanine nucleotide exchange factor activity is enhanced by lipid binding (PubMed:24058294). Accelerates GTP binding by ARFs of all three classes. Guanine nucleotide exchange protein for ARF6; mediating internalisation of beta-1 integrin.
PERQ_SEDLI,Cluster-23110.0,2,NA
AP2L1_ARATH,Cluster-49973.0,4,Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways.
LEA65_ARATH,Cluster-29266.0,4,NA
PATL4_ARATH,Cluster-51894.0,5,Carrier protein that may be involved in membrane-trafficking events associated with cell plate formation during cytokinesis. Binds to some hydrophobic molecules such as phosphoinositides and promotes their transfer between the different cellular sites.
WRK35_ARATH,Cluster-28852.0,5,Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'); a frequently occurring elicitor-responsive cis-acting element.
AIL6_ARATH,Cluster-43828.0,5,Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways.
CCD31_ARATH|CCD32_ARATH,Cluster-35179.0,5,|
PUM12_ARATH,Cluster-38973.0,5,Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs.
PLDA1_TOBAC,Cluster-39820.0,1,Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond. Plays an important role in various cellular processes.
FLZ8_ARATH,Cluster-28704.1,5,May act as an adapter to facilitate the interaction of SnRK1 complex with effector proteins; conferring tissue- and stimulus-type specific differences in the SnRK1 regulation pathway.
OFT23_ARATH,Cluster-24319.0,4,Has myotropic activity targeting the genital tract.
KINX_DICDI,Cluster-21500.1,4,Catalyzes the transfer of the gamma-phospho group of ATP to thymidine to generate dTMP in the salvage pathway of pyrimidine synthesis. The dTMP serves as a substrate for DNA polymerase during viral DNA replication. Allows the virus to be reactivated and to grow in non-proliferative cells lacking a high concentration of phosphorylated nucleic acid precursors.
HBP1A_WHEAT,Cluster-25860.0,5,Binds to the hexamer motif 5'-ACGTCA-3' of histone gene promoters.
CLE27_ARATH,Cluster-27078.0,4,Extracellular signal peptide that regulates cell fate. Represses root apical meristem maintenance.
Y3795_ARATH,Cluster-29874.0,5,NA
LGUL_SHIFL,Cluster-34523.0,3,Catalyzes the conversion of hemimercaptal; formed from methylglyoxal and glutathione; to S-lactoylglutathione.
TCP8_ARATH,Cluster-34955.0,2,NA
FLA21_ARATH,Cluster-36429.0,5,May be a cell surface adhesion protein.
CYSG1_CROS8,Cluster-38845.0,6,Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally; it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
NA,Cluster-38666.0,4,NA
NA,Cluster-53216.0,1,NA
NA,Cluster-24624.0,4,NA
NA,Cluster-32193.0,4,NA
NA,Cluster-46341.0,2,NA
NA,Cluster-55180.0,1,NA
NA,Cluster-23734.0,5,NA
NA,Cluster-55650.3,1,NA
NA,Cluster-34670.0,4,NA
NA,Cluster-25590.0,4,NA
NA,Cluster-29075.0,4,NA
NA,Cluster-42710.0,6,NA
NA,Cluster-26226.1,1,NA
NA,Cluster-57437.1,6,NA
NA,Cluster-55778.1,4,NA
NA,Cluster-55187.0,5,NA
NA,Cluster-50321.0,5,NA
NA,Cluster-27414.0,4,NA
NA,Cluster-36918.0,3,NA
NA,Cluster-20778.0,3,NA
NA,Cluster-42303.0,1,NA
NA,Cluster-27002.0,4,NA
NA,Cluster-50650.1,2,NA
NA,Cluster-50650.0,2,NA
NA,Cluster-54202.1,5,NA
NA,Cluster-33314.0,2,NA
NA,Cluster-2601.0,5,NA
NA,Cluster-40664.0,1,NA
NA,Cluster-49027.0,4,NA
NA,Cluster-53635.0,3,NA
NA,Cluster-42138.0,2,NA
NA,Cluster-42564.8,4,NA
NA,Cluster-49787.0,4,NA
NA,Cluster-50974.0,1,NA
NA,Cluster-818.0,2,NA
NA,Cluster-40368.0,1,NA
NA,Cluster-34186.0,5,NA
NA,Cluster-43563.0,4,NA
NA,Cluster-39652.0,6,NA
NA,Cluster-23795.0,4,NA
NA,Cluster-44379.0,4,NA
NA,Cluster-34359.0,6,NA
NA,Cluster-52435.0,2,NA
NA,Cluster-37564.0,6,NA
NA,Cluster-3752.0,2,NA
NA,Cluster-35916.0,2,NA
NA,Cluster-42621.0,1,NA
NA,Cluster-18942.0,2,NA
NA,Cluster-28776.0,5,NA
NA,Cluster-28351.0,5,NA
NA,Cluster-46992.0,4,NA
NA,Cluster-42291.0,4,NA
NA,Cluster-27210.0,2,NA
NA,Cluster-51900.0,4,NA
NA,Cluster-26752.0,5,NA
NA,Cluster-618.4,5,NA
NA,Cluster-49735.0,5,NA
NA,Cluster-48255.0,1,NA
NA,Cluster-27760.0,5,NA
NA,Cluster-42669.0,6,NA
NA,Cluster-35006.0,2,NA
NA,Cluster-31023.0,4,NA
NA,Cluster-49838.0,1,NA
NA,Cluster-36358.0,4,NA
NA,Cluster-55638.0,7,NA
NA,Cluster-51653.0,2,NA
NA,Cluster-56265.4,4,NA
NA,Cluster-39054.0,1,NA
NA,Cluster-45806.3,1,NA
NA,Cluster-32702.0,7,NA
NA,Cluster-54559.0,7,NA
NA,Cluster-35841.0,7,NA
NA,Cluster-38418.0,7,NA
NA,Cluster-53424.0,5,NA
NA,Cluster-44294.0,5,NA
NA,Cluster-32109.0,4,NA
NA,Cluster-50805.0,1,NA
NA,Cluster-35565.0,5,NA
NA,Cluster-22818.0,2,NA
NA,Cluster-38012.0,2,NA
NA,Cluster-44484.1,5,NA
NA,Cluster-24565.0,2,NA
NA,Cluster-49796.4,5,NA
NA,Cluster-14177.1,5,NA
NA,Cluster-50634.0,1,NA
NA,Cluster-31897.0,1,NA
NA,Cluster-29378.0,2,NA
NA,Cluster-41197.0,4,NA
NA,Cluster-31702.0,1,NA
NA,Cluster-45226.0,5,NA
NA,Cluster-32603.0,2,NA
NA,Cluster-40299.0,6,NA
NA,Cluster-54299.2,1,NA
NA,Cluster-56598.0,4,NA
NA,Cluster-55390.0,4,NA
NA,Cluster-50976.0,6,NA
NA,Cluster-38615.0,5,NA
NA,Cluster-28682.0,1,NA
NA,Cluster-50069.0,1,NA
NA,Cluster-50069.1,1,NA
NA,Cluster-36494.0,4,NA
NA,Cluster-1500.0,2,NA
NA,Cluster-40244.0,3,NA
NA,Cluster-44388.0,6,NA
NA,Cluster-29943.0,1,NA
NA,Cluster-28659.0,5,NA
NA,Cluster-27350.2,4,NA
NA,Cluster-52077.0,2,NA
NA,Cluster-36681.0,3,NA
NA,Cluster-37427.0,5,NA
NA,Cluster-2293.0,2,NA
NA,Cluster-35698.0,5,NA
NA,Cluster-51661.1,4,NA
NA,Cluster-47011.0,7,NA
NA,Cluster-45415.0,3,NA
NA,Cluster-47227.0,5,NA
NA,Cluster-54875.0,2,NA
NA,Cluster-21500.6,4,NA
NA,Cluster-21500.5,4,NA
NA,Cluster-26660.1,3,NA
NA,Cluster-42184.0,2,NA
NA,Cluster-32753.1,7,NA
NA,Cluster-36945.0,5,NA
NA,Cluster-53661.1,5,NA
NA,Cluster-56207.1,2,NA
NA,Cluster-56207.0,3,NA
NA,Cluster-24328.0,5,NA
NA,Cluster-53273.0,5,NA
NA,Cluster-50283.0,5,NA
NA,Cluster-52445.1,3,NA
NA,Cluster-17250.1,4,NA
NA,Cluster-36343.1,2,NA
NA,Cluster-57356.0,4,NA
NA,Cluster-28629.1,5,NA
NA,Cluster-44496.0,5,NA
NA,Cluster-36029.0,4,NA
NA,Cluster-54689.0,5,NA
NA,Cluster-49852.0,4,NA
NA,Cluster-34251.0,5,NA
NA,Cluster-32029.0,2,NA
NA,Cluster-40103.0,4,NA
NA,Cluster-23835.0,4,NA
NA,Cluster-8383.2,1,NA
NA,Cluster-35993.0,4,NA
NA,Cluster-57325.0,4,NA
NA,Cluster-24752.0,5,NA
NA,Cluster-34242.0,4,NA
NA,Cluster-28226.1,5,NA
NA,Cluster-45430.0,1,NA
NA,Cluster-56607.0,4,NA
NA,Cluster-46636.0,4,NA
NA,Cluster-26931.0,4,NA
NA,Cluster-24704.0,2,NA
NA,Cluster-26589.0,1,NA
NA,Cluster-43477.0,1,NA
NA,Cluster-45310.1,5,NA
NA,Cluster-50424.0,4,NA
NA,Cluster-42946.0,7,NA
NA,Cluster-1791.0,2,NA
NA,Cluster-41968.0,1,NA
NA,Cluster-48617.0,1,NA
NA,Cluster-34674.3,1,NA
NA,Cluster-34674.2,1,NA
NA,Cluster-49450.1,4,NA
NA,Cluster-20823.0,2,NA
NA,Cluster-42925.0,4,NA
NA,Cluster-45112.0,1,NA
NA,Cluster-51481.0,4,NA
NA,Cluster-46059.0,3,NA
NA,Cluster-16431.0,7,NA
NA,Cluster-19681.0,5,NA
NA,Cluster-24398.0,5,NA
NA,Cluster-31115.0,6,NA
NA,Cluster-38997.0,1,NA
NA,Cluster-41390.0,1,NA
NA,Cluster-44139.0,1,NA
NA,Cluster-44181.0,4,NA
NA,Cluster-49799.0,3,NA
NA,Cluster-52771.0,4,NA
NA,Cluster-54781.0,4,NA
NA,Cluster-56526.0,4,NA
NA,Cluster-5760.0,7,NA
NA,Cluster-618.3,5,NA