,pos.GO_Biological_Process_2021.Term,pos.GO_Biological_Process_2021.Overlap,pos.GO_Biological_Process_2021.P.value,pos.GO_Biological_Process_2021.Adjusted.P.value,pos.GO_Biological_Process_2021.Old.P.value,pos.GO_Biological_Process_2021.Old.Adjusted.P.value,pos.GO_Biological_Process_2021.Odds.Ratio,pos.GO_Biological_Process_2021.Combined.Score,pos.GO_Biological_Process_2021.Genes,pos.log10pval,pos.term,neg.GO_Biological_Process_2021.Term,neg.GO_Biological_Process_2021.Overlap,neg.GO_Biological_Process_2021.P.value,neg.GO_Biological_Process_2021.Adjusted.P.value,neg.GO_Biological_Process_2021.Old.P.value,neg.GO_Biological_Process_2021.Old.Adjusted.P.value,neg.GO_Biological_Process_2021.Odds.Ratio,neg.GO_Biological_Process_2021.Combined.Score,neg.GO_Biological_Process_2021.Genes,neg.log10pval,neg.term
1,regulation of primary metabolic process (GO:0080090),53/130,7.67E-35,2.61E-31,0,0,13.75387759,1080.402517,TM7SF2;PSMD8;PSMD6;PSMD7;PSMD4;SIN3B;PSMD2;PSMD3;PSMD1;HMGCS1;EDF1;LSS;PSMA5;PSMA3;PSMA4;PSMA1;PSMA2;PSME1;PSME2;MVD;IDI1;PSMB11;PSMD12;PSMD11;MVK;PSMD14;PSMD13;HMGCR;OAZ1;PSMA7;PSMB10;PSMB6;PSMB4;PSMB5;PSMB2;PSMB3;PMVK;PSAP;PSMB1;SC5D;LDLR;FDFT1;FDPS;NQO1;PSMB9;SQLE;PSMC5;PSMC3;PSMC4;FASN;PSMC1;PSMC2;DHCR7,34.11495037,regulation of primary metabolic process (GO:0080090),"positive regulation of transcription, DNA-templated (GO:0045893)",132/1183,1.13E-18,4.21E-15,0,0,2.597118391,107.3234192,APP;CCNT2;MAML2;RORA;PRDM2;RBPJ;RPS6KA5;ZMIZ1;EPC1;EP300;BTRC;SOX4;MAP3K5;MEF2A;DDX17;SMARCC1;SLC30A9;FBXW11;DYRK1A;RFX3;MRTFA;SOX11;LMO7;ISL1;RUNX1;KAT6B;KAT6A;PHIP;KMT2E;BEX1;KMT2A;TNKS;KMT2C;GATA3;RLF;GLIS1;NPAS3;RAI1;RREB1;MAP2K5;BPTF;CREBBP;JUN;ZFHX3;JAG1;POU2F1;SMAD3;AUTS2;BCL11B;IGF2;HMGA2;PBX1;SMARCA4;SMAD7;MLLT10;CDK8;BCL9;GDNF;ID2;AGO2;TCF4;BMPR1B;OGT;FGFR2;PICALM;BMPR1A;CDKN1C;KDM5A;DDX3X;BMPR2;THRA;CITED2;CHD8;SIX1;TCF20;RSF1;GLI3;GLI2;RPTOR;PPP3CA;PPP3CB;MED13;NCK2;TEAD1;TEAD2;KDM6B;NCOA2;PARP1;ATRX;ARID1A;TGFBR1;CREB1;TFDP2;TET3;WAC;ITGA6;CREB5;YAP1;HDAC4;NFAT5;KDM3A;PLAG1;MLLT3;NR2C2;LRP6;ATAD2B;SCAF8;NSD1;NRIP1;E2F3;TBL1X;TRIM44;ATF7IP;NPM1;USP22;GRHL2;MEIS2;ACVR2A;VEGFA;HIPK2;ASXL1;REST;MEIS1;KLF5;NFIB;ASXL3;ASXL2;CTNNB1;QRICH1;NAA15;AGRN;SSBP2,17.94680169,"positive regulation of transcription, DNA-templated (GO:0045893)"
2,regulation of cellular amino acid metabolic process (GO:0006521),36/54,3.23E-34,5.49E-31,0,0,39.38174274,3036.985368,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;OAZ1;PSMA7;PSMB10;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;PSMB2;PSMB3;PSMD2;PSMD3;PSMB1;PSMD1;NQO1;PSMB9;PSMA5;BCKDK;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2,33.49130575,regulation of cellular amino acid metabolic process (GO:0006521),positive regulation of transcription by RNA polymerase II (GO:0045944),109/908,8.91E-18,1.23E-14,0,0,2.786745216,109.4064609,APP;CCNT2;MAML2;RORA;PRDM2;RBPJ;RPS6KA5;ZMIZ1;EPC1;EP300;SOX4;MEF2A;DDX17;SLC30A9;MRTFA;RFX3;SOX11;LMO7;ISL1;RUNX1;KAT6B;KAT6A;PHIP;NOTCH3;BEX1;KMT2A;TNKS;KMT2C;GATA3;RLF;GLIS1;RREB1;MAP2K5;BPTF;CREBBP;JUN;ZFHX3;TGFB2;JAG1;POU2F1;SMAD3;AUTS2;BCL11B;IGF2;HMGA2;PBX1;SMARCA4;SMAD7;MLLT10;BCL9;CDK8;GDNF;AGO2;TCF4;CDK12;CDK13;BMPR1B;OGT;FGFR2;BMPR1A;DDX3X;BMPR2;THRA;CITED2;CHD8;SIX1;TCF20;RSF1;GLI3;GLI2;PPP3CA;PPP3CB;MED13;NCK2;TEAD1;KDM6B;NCOA2;PARP1;ATRX;CREB1;TFDP2;TET3;ITGA6;YAP1;HDAC4;NFAT5;PLAG1;NR2C2;LRP6;ATAD2B;NRIP1;E2F3;TBL1X;NPM1;GRHL2;MEIS2;ACVR2A;VEGFA;HIPK2;ASXL1;REST;MEIS1;KLF5;NFIB;ASXL3;ASXL2;CTNNB1;AGRN;SSBP2,17.05022116,positive regulation of transcription by RNA polymerase II (GO:0045944)
3,regulation of cellular amine metabolic process (GO:0033238),35/51,5.44E-34,6.17E-31,0,0,43.03367876,3296.132133,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;OAZ1;PSMA7;PSMB10;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;PSMB2;PSMB3;PSMD2;PSMD3;PSMB1;PSMD1;NQO1;PSMB9;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2,33.26445794,regulation of cellular amine metabolic process (GO:0033238),"negative regulation of transcription, DNA-templated (GO:0045892)",112/948,9.93E-18,1.23E-14,0,0,2.74037674,107.2889754,RB1;RIF1;PRDM5;EHMT1;PRDM2;ENO1;RBPJ;DACH1;RPS6KA5;EPC1;EP300;BTRC;MEF2A;RBFOX2;KDM2A;KDM2B;FBXW11;RFX3;ARID5B;SOX11;DICER1;ISL1;FOXP2;FOXP1;RUNX1;EID1;KAT6B;KAT6A;URI1;L3MBTL3;NEDD4L;GATA3;GLIS1;PHF21A;MBTD1;HMBOX1;ATXN1;RREB1;MAP2K5;BPTF;CREBBP;JUN;ZFHX3;CBX5;POU2F1;SMAD3;SMURF2;ATP8B1;BCL11A;CBX3;IGF2;HMGA2;IRF2BP2;FOXN3;SMARCA4;SMAD7;DLG1;YEATS2;CNOT1;ID2;CNOT2;ID3;GTF2IRD1;RCOR1;FGFR2;EZH2;CDKN1C;THRA;CITED2;CHD8;RSF1;PTPRK;PHF6;GLI3;GLI2;NIPBL;TRPS1;LRRFIP1;JARID2;USP47;KLF12;PARP1;DNMT3A;CBFA2T2;CREB1;NCOR1;TFDP2;LCOR;VGLL4;YAP1;HDAC4;NR2C2;BTAF1;CUX2;CUX1;NSD1;MXI1;NRIP1;TBL1X;FNIP1;JAZF1;ATF7IP;USP9X;ACVR2B;MEIS2;GATAD2B;VEGFA;REST;NR6A1;CTNNB1;BCOR;TRIM33,17.00314022,"negative regulation of transcription, DNA-templated (GO:0045892)"
4,"antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:0002479)",39/73,1.29E-31,1.09E-28,0,0,22.63799963,1610.206123,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;PSMA7;PSMB10;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;PSMB2;PSMB3;PSMD2;PSMD3;PSMB1;PSMD1;B2M;PDIA3;TAP2;TAP1;TAPBP;PSMB9;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2;CALR,30.89069906,"antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:0002479)",regulation of transcription by RNA polymerase II (GO:0006357),199/2206,2.52E-17,2.35E-14,0,0,2.10350353,80.39323894,RB1;APP;MAML2;JMJD1C;ENO1;RBPJ;IKZF2;BACH2;RPS6KA5;ZMIZ1;EPC1;SOX4;SOX5;MEF2A;DDX17;SMARCC1;EBF1;RFX3;MRTFA;SOX11;DICER1;ISL1;RUNX1;EID1;RFX7;ATF7;URI1;BEX1;TSHZ1;TSHZ2;NEDD4L;BAZ2B;GATA3;MED12L;RREB1;CREBBP;JUN;JAG1;BCL11B;BCL11A;PBX3;IGF2;IRF2BP2;PBX1;SMARCA4;MLLT10;ID2;AGO2;ID3;GTF2IRD1;CDK12;CDK13;RCOR1;EZH2;CITED2;TCF20;RSF1;HIF3A;PHF6;GLI3;GLI2;PPP3CA;NIPBL;PPP3CB;MED13;TEAD1;TEAD2;BRD3;NCOA2;PARP1;BAZ1B;NCOR1;TET3;YAP1;CUX2;CUX1;NSD1;TBL1X;NPM1;USP9X;GRHL2;GATAD2B;VEGFA;HIPK2;NR6A1;NFIB;CTNNB1;AGRN;CCNT2;RIF1;PRDM5;ZBTB20;RORA;PRDM2;ARID4B;DACH1;EP300;SLC30A9;KDM2A;KDM2B;ARID5B;LMO7;FOXP2;PIAS2;FOXP1;DMTF1;KAT6B;KAT6A;PHIP;TOX;KMT2A;TNKS;KMT2C;RLF;GLIS1;PHF21A;NPAS3;RAI1;HMBOX1;ATXN1;CAMTA1;RPRD1A;MAP2K5;BPTF;ZFHX3;ZFHX2;POU2F1;SMAD3;CBX5;AUTS2;SMURF2;HMGA2;SMAD7;CDK8;BCL9;DLG1;YEATS2;GDNF;CNOT1;CNOT2;JMY;PHF14;TCF4;BMPR1B;OGT;FGFR2;BMPR1A;KDM5B;DDX3X;BMPR2;THRA;CHD8;SIX1;CHD4;CHD2;TRPS1;NCK2;LRRFIP1;KDM6B;KLF12;ATRX;DNMT3A;ARID1A;CREB1;TFDP2;LCOR;ITGA6;KDM7A;CREB5;HDAC4;NFAT5;KDM3A;PLAG1;NR2C2;LRP6;ATAD2B;MXI1;NRIP1;RBBP8;E2F3;FNIP1;JAZF1;MGA;ARID3B;ACVR2B;MEIS2;ACVR2A;ASXL1;TNRC6C;REST;MEIS1;KLF5;ASXL3;ASXL2;BCOR;SSBP2;TRIM33;TNRC6A;TNRC6B,16.59818467,regulation of transcription by RNA polymerase II (GO:0006357)
5,antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590),40/78,1.83E-31,1.24E-28,0,0,20.79166667,1471.576972,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;IFI30;PSMA7;PSMB10;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;PSMB2;PSMB3;PSMD2;PSMD3;PSMB1;PSMD1;B2M;PDIA3;TAP2;TAP1;TAPBP;PSMB9;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2;CALR,30.73816875,antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590),negative regulation of transcription by RNA polymerase II (GO:0000122),87/684,7.57E-16,5.64E-13,0,0,2.937397833,102.2711128,RB1;RIF1;THRA;CITED2;CHD8;PRDM5;PRDM2;ENO1;RBPJ;PHF6;GLI3;GLI2;NIPBL;DACH1;TRPS1;EPC1;EP300;LRRFIP1;MEF2A;KLF12;PARP1;KDM2B;ATRX;DNMT3A;ARID5B;SOX11;DICER1;ISL1;FOXP2;FOXP1;RUNX1;EID1;NCOR1;LCOR;HDAC4;YAP1;URI1;NEDD4L;GATA3;NR2C2;GLIS1;PHF21A;HMBOX1;ATXN1;CUX2;CUX1;NSD1;MXI1;NRIP1;TBL1X;FNIP1;RREB1;MAP2K5;JAZF1;BPTF;CREBBP;JUN;ZFHX3;CBX5;SMAD3;SMURF2;USP9X;BCL11A;IGF2;IRF2BP2;HMGA2;ACVR2B;MEIS2;GATAD2B;SMARCA4;VEGFA;SMAD7;DLG1;REST;NR6A1;YEATS2;NFIB;CNOT1;CNOT2;ID2;NEDD4;ID3;GTF2IRD1;BCOR;TRIM33;FGFR2;EZH2,15.12079142,negative regulation of transcription by RNA polymerase II (GO:0000122)
6,negative regulation of cell cycle G2/M phase transition (GO:1902750),34/57,5.94E-30,3.37E-27,0,0,29.04032766,1954.278941,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;PSMA7;PSMB10;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;PSMB2;PSMB3;PSMD2;PSMD3;PSMB1;PSMD1;PSMB9;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2;ATF5,29.22599806,negative regulation of cell cycle G2/M phase transition (GO:1902750),negative regulation of cellular macromolecule biosynthetic process (GO:2000113),70/547,4.33E-13,2.69E-10,0,0,2.92286017,83.20500403,RB1;CDKN1C;GSK3B;BMPR2;DDX3X;THRA;CITED2;CHD8;PRDM5;EHMT1;RSF1;ENO1;PTPRK;RBPJ;GLI3;NIPBL;DACH1;RPS6KA5;EPC1;JARID2;BTRC;USP47;RBFOX2;IGFBP5;DAPK1;FBXW11;RFX3;ARID5B;CBFA2T2;FOXP2;FOXP1;EID1;NCOR1;TFDP2;KAT6B;KAT6A;VGLL4;HDAC4;DDX6;L3MBTL3;GATA3;PDS5A;FXR1;MBTD1;HMBOX1;BTAF1;ATXN1;IGF2BP1;IGF2BP3;IGF2BP2;ATF7IP;JUN;CBX5;POU2F1;SMURF2;ATP8B1;CBX3;HMGA2;FOXN3;SMARCA4;REST;YEATS2;CNOT1;ID2;ID3;CTNNB1;BCOR;TRIM33;RCOR1;EZH2,12.36305263,negative regulation of cellular macromolecule biosynthetic process (GO:2000113)
7,aerobic electron transport chain (GO:0019646),37/70,7.83E-30,3.81E-27,0,0,22.0831052,1479.991155,NDUFB9;NDUFB8;NDUFB7;NDUFA11;NDUFB10;NDUFB6;UQCRB;NDUFA12;NDUFB11;NDUFB4;NDUFB2;UQCR10;COX6A1;COX5B;COX7C;COX5A;UQCRFS1;CYC1;NDUFV2;NDUFV1;NDUFA8;NDUFA5;NDUFA3;NDUFA2;NDUFA1;NDUFC1;COX6C;COX6B1;NDUFS8;NDUFS7;UQCRQ;NDUFS5;NDUFAB1;NDUFS3;UQCRC1;NDUFS2;UQCRC2,29.10605127,aerobic electron transport chain (GO:0019646),regulation of cell migration (GO:0030334),58/408,5.94E-13,3.09E-10,0,0,3.280861389,92.36406769,ITGB1;CITED2;ZMYND8;PTPRK;ROBO1;IGF1R;DOCK10;PPP3CA;DACH1;DAG1;EPHB2;ARID2;APPL1;EPHA4;SEMA6A;IGFBP5;LIMCH1;LMO4;ACTN4;MIF;TGFBR1;TIAM1;FRMD5;NUMB;ITGA6;SINHCAF;ROR2;BEX4;KANK1;MACF1;ROCK1;SEMA3C;SEMA3D;PDGFA;PAK1;PDGFC;SRGAP3;SLIT2;SRGAP2;SRGAP1;SCAI;SASH1;MAP4K4;NTNG1;CARMIL1;JAG1;YTHDF3;INSR;LAMB1;SEMA4G;PLET1;PTK2;VEGFA;SMAD7;TJP1;AFDN;APC;NF1,12.22642476,regulation of cell migration (GO:0030334)
8,regulation of transcription from RNA polymerase II promoter in response to hypoxia (GO:0061418),38/75,1.07E-29,4.56E-27,0,0,20.24481654,1350.43333,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;PSMA7;PSMB10;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;PSMB2;UBB;PSMB3;PSMD2;PSMD3;PSMB1;UBC;PSMD1;ELOB;ELOC;STOX1;PSMB9;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2,28.9696744,regulation of transcription from RNA polymerase II promoter in response to hypoxia (GO:0061418),chromatin remodeling (GO:0006338),27/103,6.64E-13,3.09E-10,0,0,6.909558068,193.7446964,RB1;KDM5A;HDAC4;KDM5B;CHD8;CHD4;RSF1;BAZ2B;CECR2;PAK1;SMARCAD1;JARID2;BPTF;KDM6A;KDM6B;SMARCC1;PBRM1;KDM4B;NPM1;CBX3;ATRX;HMGA2;ARID1A;BAZ1B;GATAD2B;SMARCA4;HNRNPC,12.17766052,chromatin remodeling (GO:0006338)
9,mitochondrial ATP synthesis coupled electron transport (GO:0042775),37/71,1.56E-29,5.89E-27,0,0,21.43247205,1421.635736,NDUFB9;NDUFB8;NDUFB7;NDUFA11;NDUFB10;NDUFB6;UQCRB;NDUFA12;NDUFB11;NDUFB4;NDUFB2;UQCR10;COX6A1;COX5B;COX7C;COX5A;UQCRFS1;CYC1;NDUFV2;NDUFV1;NDUFA8;NDUFA5;NDUFA3;NDUFA2;NDUFA1;NDUFC1;COX6C;COX6B1;NDUFS8;NDUFS7;UQCRQ;NDUFS5;NDUFAB1;NDUFS3;UQCRC1;NDUFS2;UQCRC2,28.80715552,mitochondrial ATP synthesis coupled electron transport (GO:0042775),"regulation of transcription, DNA-templated (GO:0006355)",186/2244,1.17E-12,4.86E-10,0,0,1.881082514,51.67493046,RB1;CCNT2;PRDM5;EHMT1;ZBTB20;JMJD1C;RORA;PRDM2;ARID4B;ENO1;RBPJ;IKZF2;BACH2;DACH1;RPS6KA5;ZMIZ1;EPC1;EP300;BTRC;SOX4;MAP3K5;SOX5;MEF2A;DDX17;SMARCC1;RBFOX2;KDM2A;KDM2B;FBXW11;DYRK1A;EBF1;RFX3;ARID5B;SOX11;ISL1;FOXP2;PIAS2;FOXP1;RUNX1;EID1;DMTF1;RFX7;KAT6B;KAT6A;ATF7;PHIP;TOX;KMT2E;URI1;L3MBTL3;KMT2A;TSHZ1;TSHZ2;BAZ2B;GATA3;NLK;RLF;GLIS1;MED12L;NPAS3;MBTD1;SBNO1;RAI1;HMBOX1;ATXN1;CAMTA1;RREB1;BPTF;CREBBP;JUN;ZFHX3;ZFHX2;POU2F1;SMAD3;CBX5;BCL11B;SMURF2;ATP8B1;BCL11A;CBX3;INSR;PBX3;IGF2;HMGA2;IRF2BP2;FOXN3;PBX1;SMARCA4;SMAD7;YEATS2;ID2;CNOT2;JMY;PHF14;ID3;TCF4;GTF2IRD1;OGT;CDK14;RCOR1;EZH2;PICALM;CDKN1C;KDM5A;SETD5;KDM5B;THRA;CITED2;CHD8;CHD7;SIX1;CHD4;TCF20;RSF1;PTPRK;HIF3A;CHD2;PHF6;GLI3;GLI2;NIPBL;PPP3CB;MED13;TRPS1;HMG20A;ERC1;LRRFIP1;JARID2;TEAD1;TEAD2;BRD3;NCOA2;USP47;KLF12;ATRX;BAZ1B;CBFA2T2;ARID1A;TGFBR1;CREB1;NCOR1;TFDP2;WAC;LCOR;VGLL4;KDM7A;CREB5;YAP1;HDAC4;NFAT5;KDM3A;PLAG1;MLLT3;NR2C2;LRP6;BTAF1;CUX2;CUX1;NSD1;MXI1;RBBP8;E2F3;GPBP1L1;TBL1X;TRIM44;ATF7IP;NPM1;MGA;USP22;ARID3B;ACVR2B;GRHL2;MEIS2;VEGFA;HIPK2;REST;MEIS1;KLF5;NR6A1;NFIB;CTNNB1;QRICH1;NAA15;BCOR;SSBP2;TRIM33,11.93043739,"regulation of transcription, DNA-templated (GO:0006355)"
10,pre-replicative complex assembly (GO:0036388),35/64,5.64E-29,1.74E-26,0,0,23.7264606,1543.308712,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;PSMA7;PSMB10;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;PSMB2;UBB;PSMB3;PSMD2;PSMD3;PSMB1;UBC;PSMD1;PSMB9;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2,28.24907046,pre-replicative complex assembly (GO:0036388),positive regulation of nucleic acid-templated transcription (GO:1903508),66/511,1.36E-12,5.06E-10,0,0,2.94644275,80.51302281,CDKN1C;KDM5A;CITED2;CHD8;SIX1;RORA;RSF1;GLI3;GLI2;PPP3CB;MED13;ZMIZ1;EPC1;EP300;BTRC;TEAD1;TEAD2;SOX4;MAP3K5;SMARCC1;FBXW11;DYRK1A;RFX3;SOX11;ARID1A;TGFBR1;RUNX1;CREB1;KAT6B;KAT6A;WAC;PHIP;CREB5;KMT2E;HDAC4;YAP1;KDM3A;KMT2A;GATA3;MLLT3;RLF;NPAS3;LRP6;RAI1;NSD1;TBL1X;RREB1;TRIM44;ATF7IP;CREBBP;JUN;NPM1;ZFHX3;SMAD3;USP22;HMGA2;HIPK2;SMARCA4;REST;NFIB;ID2;CTNNB1;TCF4;QRICH1;NAA15;PICALM,11.86731408,positive regulation of nucleic acid-templated transcription (GO:1903508)
11,regulation of cellular ketone metabolic process (GO:0010565),35/64,5.64E-29,1.74E-26,0,0,23.7264606,1543.308712,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;OAZ1;PSMA7;PSMB10;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;PSMB2;PSMB3;PSMD2;PSMD3;PSMB1;PSMD1;NQO1;PSMB9;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2,28.24907046,regulation of cellular ketone metabolic process (GO:0010565),protein phosphorylation (GO:0006468),63/496,9.27E-12,3.14E-09,0,0,2.883067428,73.24089243,APP;GSK3B;SMG1;BMPR2;IGF1R;PPP3CB;RPS6KA5;AKT3;TLK2;NEK1;TLK1;ERC1;EPHB2;PRKG1;MAP3K5;PDK1;EPHA4;PRKCH;CAMK1D;CSNK2A1;DAPK1;DYRK1A;LMTK2;BAZ1B;TGFBR1;CREB1;SIK3;TNIK;ROCK1;TNKS;NLK;STK3;PAK1;PRDX4;ABL2;FYN;MAP4K3;MAP2K6;MAP4K4;CDK19;TGFB2;MAP3K1;PLK2;INSR;NEK7;BRAF;ACVR2B;PTK2;ACVR2A;HIPK2;SMAD7;MAPK13;CDK8;CDK6;TEC;TAOK1;PKN2;CDK12;CDK13;BMPR1B;CDK14;FGFR2;BMPR1A,11.03273379,protein phosphorylation (GO:0006468)
12,regulation of transcription from RNA polymerase II promoter in response to stress (GO:0043618),39/87,7.36E-28,2.09E-25,0,0,16.02341311,1001.087567,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;PSMA7;PSMB10;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;PSMB2;UBB;PSMB3;PSMD2;PSMD3;PSMB1;UBC;PSMD1;ELOB;ELOC;STOX1;PSMB9;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2;ATF4,27.13322081,regulation of transcription from RNA polymerase II promoter in response to stress (GO:0043618),axonogenesis (GO:0007409),40/240,1.79E-11,5.56E-09,0,0,3.916666667,96.92340462,APP;NOTCH3;SEMA3C;SEMA3D;DOCK7;EFNA5;IGSF9;GLI2;ROBO1;EFNB2;PPP3CB;RPS6KA5;BSG;DAG1;GRB10;FYN;NCAM1;SLIT3;EMB;SLIT2;EPHB2;SPTAN1;SPTBN1;EPHA5;NTNG1;EPHA4;HSP90AA1;SEMA6A;AUTS2;USP9X;RANBP9;LMTK2;SEMA4G;ISL1;PTK2;ENAH;GDNF;PIK3CA;PARD3;FGFR2,10.74722548,axonogenesis (GO:0007409)
13,NIK/NF-kappaB signaling (GO:0038061),36/74,2.16E-27,5.66E-25,0,0,18.63485477,1144.147146,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;PSMA7;PSMB10;RELB;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;PSMB2;PSMB3;PSMD2;PSMD3;PSMB1;PSMD1;NFKB2;PSMB9;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2;BIRC3,26.66491358,NIK/NF-kappaB signaling (GO:0038061),negative regulation of nucleic acid-templated transcription (GO:1903507),58/464,1.19E-10,3.42E-08,0,0,2.819836215,64.42834461,RB1;CDKN1C;THRA;CITED2;CHD8;PRDM5;EHMT1;RSF1;ENO1;PTPRK;RBPJ;GLI3;NIPBL;DACH1;RPS6KA5;EPC1;JARID2;BTRC;USP47;RBFOX2;FBXW11;RFX3;ARID5B;CBFA2T2;FOXP2;FOXP1;EID1;NCOR1;TFDP2;KAT6B;KAT6A;VGLL4;HDAC4;L3MBTL3;GATA3;MBTD1;HMBOX1;BTAF1;ATXN1;ATF7IP;JUN;CBX5;POU2F1;SMURF2;ATP8B1;CBX3;HMGA2;FOXN3;SMARCA4;REST;YEATS2;ID2;ID3;CTNNB1;BCOR;TRIM33;RCOR1;EZH2,9.922872256,negative regulation of nucleic acid-templated transcription (GO:1903507)
14,negative regulation of G2/M transition of mitotic cell cycle (GO:0010972),33/66,1.03E-25,2.51E-23,0,0,19.61427094,1128.48335,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;PSMA7;PSMB10;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;PSMB2;PSMB3;PSMD2;PSMD3;PSMB1;PSMD1;PSMB9;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2,24.98660763,negative regulation of G2/M transition of mitotic cell cycle (GO:0010972),negative regulation of cell motility (GO:2000146),25/114,3.10E-10,8.25E-08,0,0,5.448285797,119.2898713,KANK1;CITED2;ZMYND8;GATA3;PTPRK;ROBO1;DACH1;SPOCK3;DAG1;SRGAP3;SLIT2;ARID2;SRGAP2;SRGAP1;SCAI;EPHA4;JAG1;IGFBP5;LIMCH1;MIF;SMAD7;AFDN;FRMD5;NF1;SINHCAF,9.508850083,negative regulation of cell motility (GO:2000146)
15,regulation of mRNA catabolic process (GO:0061013),43/122,1.95E-25,4.42E-23,0,0,10.7615174,612.2873657,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;PSMA7;PSMB10;ZFP36L1;PSMD8;PSMB6;PSMD6;ZFP36;PSMB4;PSMD7;EXOSC4;PSMB5;PSMD4;UBB;PSMB2;PSMB3;PSMD2;PSMD3;UBC;PSMB1;PSMD1;EXOSC3;HSPA8;PSMB9;PSMA5;CARHSP1;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;HNRNPD;PSME2;PKP3,24.70962174,regulation of mRNA catabolic process (GO:0061013),phosphorylation (GO:0016310),51/400,8.02E-10,1.99E-07,0,0,2.871975024,60.14978102,APP;GSK3B;BMPR2;PPP3CB;RPS6KA5;AKT3;TLK2;NEK1;TLK1;EPHB2;PRKG1;MAP3K5;PDK1;PRKCH;CSNK2A1;DAPK1;DYRK1A;LMTK2;TGFBR1;CREB1;PIK3CA;SIK3;TNIK;ROCK1;NLK;STK3;PAK1;PGK1;FYN;MAP4K3;MAP4K4;CDK19;TGFB2;MAP3K1;PLK2;INSR;NEK7;BRAF;ACVR2B;ACVR2A;HIPK2;CDK8;CDK6;TEC;TAOK1;PKN2;CDK12;CDK13;BMPR1B;CDK14;BMPR1A,9.095732993,phosphorylation (GO:0016310)
16,interleukin-1-mediated signaling pathway (GO:0070498),38/94,3.65E-25,7.76E-23,0,0,13.36263736,751.9202052,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;PSMA7;PSMB10;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;PSMB2;UBB;PSMB3;PSMD2;PSMD3;PSMB1;UBC;PSMD1;EGR1;PSMB9;PSMA5;NFKBIA;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2;UBE2V1,24.43790003,interleukin-1-mediated signaling pathway (GO:0070498),chromatin organization (GO:0006325),27/142,1.79E-09,4.18E-07,0,0,4.556906028,91.77182313,RB1;KDM5A;HDAC4;KDM5B;SETD5;SETD2;EHMT1;RSF1;BAZ2B;PAK1;SMARCAD1;HMG20A;JARID2;BPTF;KDM6A;KDM6B;SMARCC1;PBRM1;KDM4B;NPM1;CBX3;ATRX;HMGA2;ARID1A;BAZ1B;SMARCA4;EZH2,8.746284461,chromatin organization (GO:0006325)
17,anaphase-promoting complex-dependent catabolic process (GO:0031145),36/84,5.64E-25,1.13E-22,0,0,14.74481328,823.2626011,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;PSMA7;PSMB10;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;PSMB2;UBB;PSMB3;PSMD2;PSMD3;PSMB1;UBC;PSMD1;FBXO31;PSMB9;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2,24.24841862,anaphase-promoting complex-dependent catabolic process (GO:0031145),axon guidance (GO:0007411),33/203,2.02E-09,4.42E-07,0,0,3.779974451,75.67800102,NOTCH3;SEMA3C;SEMA3D;EFNA5;IGSF9;GLI2;ROBO1;EFNB2;RPS6KA5;BSG;CHN1;DAG1;GRB10;FYN;NCAM1;SLIT3;EMB;SLIT2;EPHB2;SPTAN1;SPTBN1;EPHA5;EPHA4;SEMA6A;RANBP9;SEMA4G;PTK2;VEGFA;ENAH;TMEFF1;GDNF;PIK3CA;NFIB,8.694910157,axon guidance (GO:0007411)
18,"Wnt signaling pathway, planar cell polarity pathway (GO:0060071)",36/85,9.33E-25,1.76E-22,0,0,14.44313659,799.1580364,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;PSMA7;PSMB10;PSMD8;CDC42;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;PSMB2;PSMB3;PSMD2;PSMD3;PSMB1;PSMD1;AP2M1;PSMB9;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2;PFN1,24.03009368,"Wnt signaling pathway, planar cell polarity pathway (GO:0060071)",negative regulation of gene expression (GO:0010629),43/322,4.26E-09,8.81E-07,0,0,3.014958633,58.11254988,RB1;YAP1;APP;DDX6;DDX3X;CITED2;CELF1;ROBO1;FXR1;RPS6KA5;TASOR;CPNE1;IGF2BP1;EPC1;IGF2BP3;IGF2BP2;JARID2;DIS3L2;TGFB2;IGFBP5;DAPK1;DNMT3A;SOX11;DICER1;MIF;ATP2B1;PTBP2;RUNX1;VEGFA;FOXP1;TNRC6C;TWSG1;REST;NCOR1;CNOT1;ID2;AGO2;TNRC6A;EZH2;BMPR1A;PICALM;RBMS3;TNRC6B,8.370914102,negative regulation of gene expression (GO:0010629)
19,regulation of hematopoietic stem cell differentiation (GO:1902036),33/71,2.10E-24,3.76E-22,0,0,17.02895553,928.395536,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;PSMA7;PSMB10;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;PSMB2;PSMB3;PSMD2;PSMD3;PSMB1;PSMD1;PSMB9;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2,23.67714553,regulation of hematopoietic stem cell differentiation (GO:1902036),neuron projection morphogenesis (GO:0048812),26/140,6.01E-09,1.18E-06,0,0,4.422313484,83.71468036,APP;TRIO;ROCK1;CTNND2;DOCK7;KLK8;DOCK10;PAK1;FLRT3;CPNE1;EPHB2;SRGAP2;ATP7A;MAP4K4;MEF2A;NTNG1;FARP1;LMTK2;DICER1;ISL1;PARD3;TAOK1;CTNNB1;TNIK;FGFR2;DBN1,8.22122264,neuron projection morphogenesis (GO:0048812)
20,regulation of establishment of planar polarity (GO:0090175),36/88,4.01E-24,6.82E-22,0,0,13.60772423,733.0916424,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;PSMA7;PSMB10;PSMD8;CDC42;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;PSMB2;PSMB3;PSMD2;PSMD3;PSMB1;PSMD1;AP2M1;PSMB9;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2;PFN1,23.39683328,regulation of establishment of planar polarity (GO:0090175),transmembrane receptor protein tyrosine kinase signaling pathway (GO:0007169),49/404,9.11E-09,1.70E-06,0,0,2.706135869,50.1025131,GSK3B;IRS1;ITSN1;IRS4;PIK3C2A;IGF1R;SPRED2;UBASH3B;GRB14;GRB10;NCK2;EPHB2;APPL1;EPHA5;EPHA4;HSP90AA1;RBFOX2;LMTK2;MTSS1;TIAM1;PIK3CA;KIF16B;PHIP;ROR2;DOCK1;ROCK1;ARHGEF28;PDGFA;EFNA5;CBL;EFNB2;PAK1;ERBB3;FLRT3;PDGFC;CHN1;FYN;SHOC2;MPZL1;TIA1;ANGPT1;SORT1;INSR;IGF2;AP2B1;PTK2;VEGFA;APC;FGFR2,8.040706758,transmembrane receptor protein tyrosine kinase signaling pathway (GO:0007169)
21,SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0031146),36/89,6.42E-24,1.04E-21,0,0,13.3502701,712.9441853,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;PSMA7;PSMB10;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;PSMB2;PSMB3;PSMD2;PSMD3;PSMB1;PSMD1;FBXO6;FBXL15;FBXO31;PSMB9;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2,23.19261882,SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0031146),regulation of canonical Wnt signaling pathway (GO:0060828),36/253,1.47E-08,2.53E-06,0,0,3.232441631,58.29053631,AMER2;KANK1;GSK3B;DDX3X;TNKS;CTNND2;CUL3;CHD8;USP34;MLLT3;LYPD6;GLI3;STK3;LRP6;CDH3;ZNRF3;TNKS2;GPC3;TBL1X;BTRC;SOX4;ANKRD6;TLE4;USP47;SMURF2;IGFBP4;FZD6;MCC;APC;GNAQ;PSME4;CCDC88C;CTNNB1;CDK14;FGFR2;RBMS3,7.831621157,regulation of canonical Wnt signaling pathway (GO:0060828)
22,regulation of hematopoietic progenitor cell differentiation (GO:1901532),33/75,1.88E-23,2.91E-21,0,0,15.40390013,806.0267331,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;PSMA7;PSMB10;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;PSMB2;PSMB3;PSMD2;PSMD3;PSMB1;PSMD1;PSMB9;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2,22.72495663,regulation of hematopoietic progenitor cell differentiation (GO:1901532),regulation of cell differentiation (GO:0045595),27/156,1.49E-08,2.53E-06,0,0,4.059346543,73.14537681,ROCK1;SIX1;GATA3;TRPS1;DAG1;CLASP1;DDX17;CREBBP;ZFHX3;ZFHX2;IGF2;ISL1;PTK2;TGFBR1;RUNX1;SMAD7;TIAM1;REST;CDK6;GDNF;APC;ID2;ST7;NF1;SINHCAF;BMPR1B;FGFR2,7.825553495,regulation of cell differentiation (GO:0045595)
23,cellular response to hypoxia (GO:0071456),42/131,5.02E-23,7.42E-21,0,0,9.315545026,478.320124,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;PSMA7;PSMB10;ZFP36L1;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;UBB;PSMB2;PSMB3;PSMD2;PSMD3;UBC;PSMB1;PSMD1;ELOB;ELOC;STOX1;BNIP3L;PSMB9;PSMA5;PSMA3;PSMC5;RGCC;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2;STUB1,22.2994779,cellular response to hypoxia (GO:0071456),regulation of gene expression (GO:0010468),96/1079,2.38E-08,3.85E-06,0,0,1.946398509,34.16835788,RB1;GSK3B;RPL5;APP;DDX3X;TFRC;CELF1;CITED2;PRDM5;CHD7;JMJD1C;SIX1;RORA;PRDM2;RBPJ;AFF3;AFF4;ROBO1;CDH3;RPS6KA5;CPNE1;EP300;HMG20A;ERC1;CD36;EPHB2;TEAD2;SOX4;KDM6A;KDM6B;NCOA2;ATRX;RFX3;RC3H1;SOX11;DICER1;MIF;PTBP2;TGFBR1;FOXP1;RUNX1;DMTF1;KAT6B;ATF7;RBMS3;YAP1;HDAC4;ROCK1;PLAG1;GATA3;NLK;NR2C2;SBNO1;ATXN1;CUX2;PCBP4;TRA2B;NSD1;IGF2BP1;IGF2BP3;GPBP1L1;IGF2BP2;RREB1;TRIM44;CREBBP;ZFHX3;TGFB2;SMAD3;ANGPT1;SORT1;INSR;IGF2;HMGA2;BRAF;FOXN3;PUM1;ACVR2B;VEGFA;PUM2;CLK1;TNRC6C;AFDN;REST;CDK6;GDNF;ID2;FUBP1;AGO2;UBAP2;GTF2IRD1;SSBP2;TNRC6A;EZH2;PICALM;TNRC6B;BMPR1A,7.623890592,regulation of gene expression (GO:0010468)
24,tumor necrosis factor-mediated signaling pathway (GO:0033209),39/116,2.51E-22,3.56E-20,0,0,9.973336757,496.0384401,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;ILK;PSMA7;PSMB10;PSMD8;PYCARD;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;PSMB2;PSMB3;PSMD2;PSMD3;PSMB1;PSMD1;EIF5A;STAT1;PSMB9;NFKBIA;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2;BIRC3,21.60026906,tumor necrosis factor-mediated signaling pathway (GO:0033209),heart development (GO:0007507),27/164,4.45E-08,6.75E-06,0,0,3.820684016,64.67778203,BMPR2;CITED2;CHD7;ECE1;GLI2;AKAP13;NIPBL;ERBB3;FLRT3;GPC3;PLCE1;SOX4;KDM6A;MEF2A;KDM6B;TGFB2;CXADR;INSR;ISL1;PTK2;TGFBR1;VEGFA;ID2;NF1;TAB2;BCOR;FGF12,7.351878281,heart development (GO:0007507)
25,negative regulation of mitotic cell cycle phase transition (GO:1901991),35/92,3.13E-22,4.26E-20,0,0,12.05354059,596.8303823,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;PSMA7;PSMB10;ZFP36L1;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;PSMB2;PSMB3;PSMD2;PSMD3;PSMB1;PSMD1;PSMB9;PSMA5;PSMA3;PSMC5;PSMA4;RGCC;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2,21.50406677,negative regulation of mitotic cell cycle phase transition (GO:1901991),ventricular septum morphogenesis (GO:0060412),28-Nov,4.53E-08,6.75E-06,0,0,12.41973473,210.0227968,TGFB2;BMPR2;CITED2;SLIT3;SOX11;SLIT2;SOX4;TGFBR1;ROBO1;SMAD7;BMPR1A,7.344097415,ventricular septum morphogenesis (GO:0060412)
26,"mitochondrial electron transport, NADH to ubiquinone (GO:0006120)",24/39,5.59E-22,7.31E-20,0,0,31.12295082,1523.025853,NDUFB9;NDUFA8;NDUFB8;NDUFB7;NDUFA11;NDUFB10;NDUFB6;NDUFA5;NDUFA12;NDUFB11;NDUFB4;NDUFA3;NDUFA2;NDUFB2;NDUFA1;NDUFC1;NDUFS8;NDUFS7;NDUFS5;NDUFAB1;NDUFS3;NDUFS2;NDUFV2;NDUFV1,21.25253892,"mitochondrial electron transport, NADH to ubiquinone (GO:0006120)",negative regulation of cell migration (GO:0030336),25/144,4.76E-08,6.83E-06,0,0,4.068304245,68.59002557,KANK1;CITED2;ZMYND8;PTPRK;ROBO1;DACH1;DAG1;SRGAP3;SLIT2;ARID2;SRGAP2;SRGAP1;SCAI;CLASP1;EPHA4;JAG1;IGFBP5;LIMCH1;MIF;MCC;SMAD7;AFDN;NF1;SINHCAF;BMPR1A,7.322035872,negative regulation of cell migration (GO:0030336)
27,regulation of mRNA stability (GO:0043488),43/146,6.62E-22,8.34E-20,0,0,8.243509754,402.0125524,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;YBX1;PSMA7;PSMB10;ZFP36L1;PSMD8;PSMB6;PSMD6;ZFP36;PSMB4;PSMD7;EXOSC4;PSMB5;PSMD4;UBB;PSMB2;PSMB3;PSMD2;PSMD3;UBC;PSMB1;PSMD1;EXOSC3;HSPA8;PSMB9;PSMA5;CARHSP1;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;HNRNPD;PSME2,21.17930813,regulation of mRNA stability (GO:0043488),cellular protein modification process (GO:0006464),91/1025,6.25E-08,8.62E-06,0,0,1.936389142,32.12192899,GSK3B;APP;BMPR2;PLOD2;PTPRK;LAMC1;HIF3A;PTPRF;PPP3CA;PPP3CB;RPS6KA5;AKT3;TLK2;NEK1;TLK1;UBXN7;MACROD2;BTRC;PRKG1;MAP3K5;PDK1;PRKCH;CSNK2A1;IGFBP5;PARP1;FBXW11;DAPK1;IGFBP4;DYRK1A;UBE2E2;LMTK2;LMO7;FBXO11;TGFBR1;PARP8;DDB1;CREB1;CTDSP2;PSME4;SIK3;TNIK;PHPT1;MTMR3;ROCK1;TNKS;CUL3;PPM1H;TULP4;NLK;FSTL1;LTBP1;STK3;FBXL20;PAK1;TNKS2;GPC3;ABL2;FYN;MAP4K3;MAP4K4;CDK19;TGFB2;MAP3K1;ST8SIA2;PLK2;INSR;NEK7;OGA;LAMB1;BRAF;PTPN12;PTPN13;ACVR2B;PTPN14;ACVR2A;HIPK2;KTN1;PTPRD;CDK8;TEC;CDK6;TAOK1;CALU;PKN2;CDK12;PTPN4;CDK13;BMPR1B;CDK14;FBXL7;BMPR1A,7.204324897,cellular protein modification process (GO:0006464)
28,DNA-dependent DNA replication (GO:0006261),40/129,2.19E-21,2.66E-19,0,0,8.853464419,421.1653325,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;PNKP;PSMA7;PSMB10;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;UBB;PSMB2;PSMB3;PSMD2;PSMD3;UBC;POLD2;PSMB1;PSMD1;RFC3;PSMB9;PSMA5;PSMA3;PSMC5;CDC34;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2;CDK2AP1,20.6596843,DNA-dependent DNA replication (GO:0006261),positive regulation of cell migration (GO:0030335),36/269,7.31E-08,9.72E-06,0,0,3.007906968,49.42555777,ITGB1;BMPR2;SEMA3C;SEMA3D;PDGFA;RTN4;IGF1R;PPP3CA;NIPBL;PAK1;RAB25;PDGFC;EPHB2;RREB1;CLASP1;MAP4K4;CARMIL1;TGFB2;SEMA6A;SMURF2;INSR;LAMB1;ACTN4;SEMA4G;PLET1;PTK2;TGFBR1;VEGFA;TJP1;TIAM1;APC;AGO2;NUMB;ITGA6;ROR2;DOCK1,7.136273572,positive regulation of cell migration (GO:0030335)
29,Fc-epsilon receptor signaling pathway (GO:0038095),37/111,4.21E-21,4.94E-19,0,0,9.826583593,461.0338227,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;PIK3R2;BCL10;PSMA7;PSMB10;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;PSMB2;PSMB3;PSMD2;PSMD3;PSMB1;PSMD1;FOS;PSMB9;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2;CALM1,20.37579422,Fc-epsilon receptor signaling pathway (GO:0038095),positive regulation of multicellular organismal process (GO:0051240),42/345,9.42E-08,1.18E-05,0,0,2.705285351,43.76623824,KDM3A;BMPR2;TFRC;RIF1;NUMA1;THRA;ROCK1;EHMT1;SIX1;ENO1;PTN;NR2C2;RTN4;IGF1R;PDGFC;GRB10;CD36;RREB1;SOX5;KDM6B;DYNC1H1;TGFB2;PRKCH;SMAD3;CADM1;SMURF2;RFX3;SOX11;MIF;TGFBR1;VEGFA;TIAM1;REST;GDNF;APC;AGO2;MFAP2;CTNNB1;BMPR1B;OGT;EZH2;BMPR1A,7.026037291,positive regulation of multicellular organismal process (GO:0051240)
30,Fc receptor signaling pathway (GO:0038093),37/112,5.99E-21,6.79E-19,0,0,9.69505019,451.4415072,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;PIK3R2;BCL10;PSMA7;PSMB10;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;PSMB2;PSMB3;PSMD2;PSMD3;PSMB1;PSMD1;FOS;PSMB9;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2;CALM1,20.22254157,Fc receptor signaling pathway (GO:0038093),positive regulation of cellular process (GO:0048522),63/625,9.54E-08,1.18E-05,0,0,2.205862581,35.65847443,DDX3X;NUMA1;TENM4;IRS1;CELF1;CITED2;FAF1;IGF1R;RPTOR;PPP3CA;CDH3;CCND2;CSPP1;CD36;SOX4;EPHA4;USP47;CAMK1D;CSNK2A1;SOX11;DICER1;ACTN4;ISL1;TGFBR1;TIAM1;FRMD5;GAREM1;PARD3;PHIP;SINHCAF;ANKRD17;HDAC4;CUL3;PDGFA;PTN;LRP6;FXR1;DPP4;EFNB2;PAK1;RAB25;ERBB3;PDGFC;DYNC1H1;NPM1;TGFB2;ZFHX3;INSR;IGF2;HMGA2;NAP1L1;MEIS2;PTK2;VEGFA;TJP1;CNOT6;MEIS1;APC;GDNF;CDK13;BMPR1B;FGFR2;EZH2,7.02050926,positive regulation of cellular process (GO:0048522)
31,regulation of G2/M transition of mitotic cell cycle (GO:0010389),42/149,1.28E-20,1.40E-18,0,0,7.741068815,354.5929558,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;DCTN1;CETN2;SSNA1;PSMA7;PSMB10;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;TUBA1A;PSMB5;PSMD4;PSMB2;HAUS7;PSMB3;PSMD2;PSMD3;PSMB1;PSMD1;STOX1;RCC2;TUBG1;TUBB4B;PSMB9;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2,19.89360483,regulation of G2/M transition of mitotic cell cycle (GO:0010389),neuron projection development (GO:0031175),27/171,1.08E-07,1.27E-05,0,0,3.6336074,58.27168754,RB1;APP;GSK3B;TRIO;ROCK1;CTNND2;DOCK7;STMN2;PPP1R9A;KLK8;DOCK10;PAK1;FLRT3;EPHB2;SRGAP2;ATP7A;GPM6B;MAP4K4;EPHA4;ADGRV1;LAMB1;DICER1;GDNF;NEDD4;TAOK1;TNIK;DBN1,6.964723913,neuron projection development (GO:0031175)
32,mitochondrial respiratory chain complex assembly (GO:0033108),33/90,1.90E-20,2.02E-18,0,0,11.34126163,515.004953,NDUFB9;NDUFB8;NDUFB7;NDUFA11;NDUFB10;NDUFB6;NDUFA12;NDUFB11;NDUFB4;COX17;NDUFB2;OMA1;UQCRFS1;NDUFV2;NDUFV1;NDUFA8;NDUFA5;PET100;UQCC2;NDUFA3;NDUFA2;NDUFA1;NDUFC1;NDUFAF8;NDUFS8;NDUFS7;NDUFS5;SDHAF1;NDUFAB1;NDUFS3;NDUFS2;NDUFAF3;COX20,19.72124588,mitochondrial respiratory chain complex assembly (GO:0033108),embryonic organ development (GO:0048568),16/66,1.09E-07,1.27E-05,0,0,6.162601626,98.77603543,TGFB2;KMT2A;PBX3;COBL;PDGFA;GATA3;RBPJ;GLI3;PBX1;GLI2;COL2A1;GDNF;TEAD1;TEAD2;FGFR2;BMPR1A,6.961002793,embryonic organ development (GO:0048568)
33,regulation of stem cell differentiation (GO:2000736),33/91,2.84E-20,2.93E-18,0,0,11.14513426,501.6153588,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;PSMA7;PSMB10;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;PSMB2;PSMB3;PSMD2;PSMD3;PSMB1;PSMD1;PSMB9;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2,19.54653729,regulation of stem cell differentiation (GO:2000736),regulation of Wnt signaling pathway (GO:0030111),21/111,1.23E-07,1.39E-05,0,0,4.506979911,71.70566675,APP;RNF43;MACF1;AMER2;KANK1;ZRANB1;CSNK2A1;CTNND2;NLK;RUNX1;SMARCA4;TIAM1;GNAQ;GRB10;GPC3;CTNNB1;BTRC;CDK14;TRABD2B;FGFR2;VGLL4,6.909588239,regulation of Wnt signaling pathway (GO:0030111)
34,non-canonical Wnt signaling pathway (GO:0035567),38/124,3.50E-20,3.50E-18,0,0,8.687472804,389.1871868,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;PSMA7;PSMB10;PSMD8;CDC42;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;PSMB2;PSMB3;PSMD2;PSMD3;PSMB1;PSMD1;AP2M1;WNT4;PSMB9;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2;PFN1;CALM1,19.45581316,non-canonical Wnt signaling pathway (GO:0035567),regulation of anatomical structure morphogenesis (GO:0022603),22/123,1.75E-07,1.92E-05,0,0,4.209216627,65.48547667,EGLN1;EPHA4;GSK3B;ZRANB1;SPARC;RC3H1;NEDD4L;EFNA5;TANC2;PAK1;GDNF;ZMYM4;NEDD4;CHN1;DAG1;NF1;CTNNB1;PHIP;TNIK;FGFR2;CLASP1;SH3D19,6.756597173,regulation of anatomical structure morphogenesis (GO:0022603)
35,cellular response to tumor necrosis factor (GO:0071356),47/194,6.42E-20,6.24E-18,0,0,6.325110107,279.5180291,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;ILK;CIB1;YBX3;PSMA7;PSMB10;ZFP36L1;PSMD8;PSMB6;PYCARD;PSMD6;PSMB4;ZFP36;PSMD7;PSMB5;PSMD4;PSMB2;PSMB3;PSMD2;GPER1;PSMD3;PSMB1;PSMD1;GBP2;GBP3;CCL25;EIF5A;STAT1;PSMB9;PSMA5;NFKBIA;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2;BIRC3,19.19225683,cellular response to tumor necrosis factor (GO:0071356),ventricular septum development (GO:0003281),Dec-38,1.85E-07,1.97E-05,0,0,8.863593896,137.411242,TGFB2;BMPR2;CITED2;SLIT3;SOX11;GATA3;SLIT2;SOX4;TGFBR1;ROBO1;SMAD7;BMPR1A,6.732815703,ventricular septum development (GO:0003281)
36,cellular response to interleukin-1 (GO:0071347),42/155,6.62E-20,6.25E-18,0,0,7.327710754,323.6073052,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;PSMA7;PSMB10;PSMD8;PYCARD;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;UBB;PSMB2;PSMB3;PSMD2;PSMD3;UBC;PSMB1;PSMD1;GBP2;GBP3;CCL25;EGR1;PSMB9;NFKBIA;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2;UBE2V1,19.17936879,cellular response to interleukin-1 (GO:0071347),histone lysine demethylation (GO:0070076),26-Oct,2.38E-07,2.47E-05,0,0,11.98484848,182.768292,KDM5A;KDM6B;KDM5B;KDM3A;KDM4B;KDM2A;KDM2B;JMJD1C;KDM7A;KDM6A,6.622967388,histone lysine demethylation (GO:0070076)
37,regulation of cell cycle phase transition (GO:1901987),33/95,1.34E-19,1.23E-17,0,0,10.42389165,453.0060626,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;PSMA7;PSMB10;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;PSMB2;PSMB3;PSMD2;PSMD3;PSMB1;PSMD1;PSMB9;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2,18.87376038,regulation of cell cycle phase transition (GO:1901987),regulation of cell-matrix adhesion (GO:0001952),15/65,5.43E-07,5.47E-05,0,0,5.771573604,83.2647192,GSK3B;MACF1;JAG1;ROCK1;LIMCH1;EFNA5;PLET1;PTK2;CDK6;NF1;CD36;UTRN;CLASP1;GPM6B;MAP4K4,6.265433063,regulation of cell-matrix adhesion (GO:0001952)
38,positive regulation of canonical Wnt signaling pathway (GO:0090263),38/130,2.19E-19,1.96E-17,0,0,8.118322336,348.7928212,PSMB11;PSMD12;VCP;PSMD11;PSMD14;PSMD13;ILK;NRARP;EGFR;PSMA7;PSMB10;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;PSMB2;PSMB3;PSMD2;PSMD3;PSMB1;PSMD1;DAPK3;PSMB9;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2,18.65887942,positive regulation of canonical Wnt signaling pathway (GO:0090263),transmembrane receptor protein serine/threonine kinase signaling pathway (GO:0007178),22/133,7.12E-07,6.99E-05,0,0,3.827981356,54.18373424,ITGB1;JUN;TGFB2;SMAD3;BMPR2;SMURF2;ZFYVE9;USP9X;PTPRK;NLK;CBL;ACVR2B;PTK2;TGFBR1;ACVR2A;SMAD7;TWSG1;ZMIZ1;PARD3;BMPR1B;BMPR1A;APPL1,6.147286155,transmembrane receptor protein serine/threonine kinase signaling pathway (GO:0007178)
39,mitochondrial respiratory chain complex I assembly (GO:0032981),26/58,5.19E-19,4.41E-17,0,0,15.82289528,666.1965688,NDUFB9;NDUFB8;NDUFB7;NDUFA11;NDUFB10;NDUFB6;NDUFA12;NDUFB11;NDUFB4;NDUFB2;NDUFV2;NDUFV1;NDUFA8;NDUFA5;NDUFA3;NDUFA2;NDUFA1;NDUFC1;NDUFAF8;NDUFS8;NDUFS7;NDUFS5;NDUFAB1;NDUFS3;NDUFS2;NDUFAF3,18.28524354,mitochondrial respiratory chain complex I assembly (GO:0032981),positive regulation of mRNA catabolic process (GO:0061014),Dec-44,1.09E-06,0.00010395,0,0,7.199392713,98.83392602,FTO;TNRC6C;ROCK1;YTHDF3;CELF1;CNOT1;AGO2;RC3H1;PABPC1;PUM1;TNRC6A;TNRC6B,5.962034634,positive regulation of mRNA catabolic process (GO:0061014)
40,NADH dehydrogenase complex assembly (GO:0010257),26/58,5.19E-19,4.41E-17,0,0,15.82289528,666.1965688,NDUFB9;NDUFB8;NDUFB7;NDUFA11;NDUFB10;NDUFB6;NDUFA12;NDUFB11;NDUFB4;NDUFB2;NDUFV2;NDUFV1;NDUFA8;NDUFA5;NDUFA3;NDUFA2;NDUFA1;NDUFC1;NDUFAF8;NDUFS8;NDUFS7;NDUFS5;NDUFAB1;NDUFS3;NDUFS2;NDUFAF3,18.28524354,NADH dehydrogenase complex assembly (GO:0010257),circulatory system development (GO:0072359),21/126,1.12E-06,0.00010395,0,0,3.860061287,52.90527989,MEF2A;KDM6B;TGFB2;CXADR;CITED2;ECE1;ISL1;TGFBR1;GLI2;AKAP13;PIK3CA;ERBB3;FLRT3;ID2;NF1;PLCE1;TAB2;BCOR;FGF12;SOX4;KDM6A,5.95235915,circulatory system development (GO:0072359)
41,cellular response to lectin (GO:1990858),35/115,1.38E-18,1.12E-16,0,0,8.577720207,352.7620119,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;BCL10;PSMA7;PSMB10;RELB;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;PSMB2;PSMB3;PSMD2;PSMD3;PSMB1;PSMD1;PSMB9;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2,17.86052605,cellular response to lectin (GO:1990858),transforming growth factor beta receptor signaling pathway (GO:0007179),17/89,1.68E-06,0.000152463,0,0,4.54639991,60.45851429,ITGB1;JUN;TGFB2;SMAD3;ZFYVE9;USP9X;PTPRK;CBL;NLK;TGFBR1;PTK2;SMAD7;TWSG1;ZMIZ1;PARD3;APPL1;BMPR1A,5.775294665,transforming growth factor beta receptor signaling pathway (GO:0007179)
42,stimulatory C-type lectin receptor signaling pathway (GO:0002223),35/115,1.38E-18,1.12E-16,0,0,8.577720207,352.7620119,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;BCL10;PSMA7;PSMB10;RELB;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;PSMB2;PSMB3;PSMD2;PSMD3;PSMB1;PSMD1;PSMB9;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2,17.86052605,stimulatory C-type lectin receptor signaling pathway (GO:0002223),neuron development (GO:0048666),22/143,2.50E-06,0.000221731,0,0,3.509760178,45.27403032,RB1;EPHA5;APP;GSK3B;TGFB2;TENM3;TENM4;ROCK1;DOCK7;STMN2;PBX3;LAMB1;THOC2;PPP1R9A;PBX1;RUNX1;GLI2;GDNF;FLRT3;NEDD4;ATP7A;GPM6B,5.602166685,neuron development (GO:0048666)
43,regulation of mitotic cell cycle phase transition (GO:1901990),44/188,4.12E-18,3.26E-16,0,0,6.026731753,241.2564487,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;DCTN1;CETN2;SSNA1;PSMA7;PSMB10;ZFP36L1;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;TUBA1A;PSMB5;PSMD4;UBB;PSMB2;HAUS7;PSMB3;PSMD2;PSMD3;UBC;PSMB1;PSMD1;TUBG1;TUBB4B;PSMB9;PSMA5;PSMA3;PSMC5;RGCC;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2,17.38526762,regulation of mitotic cell cycle phase transition (GO:1901990),post-transcriptional gene silencing by RNA (GO:0035194),20-Aug,2.79E-06,0.000236384,0,0,12.76075269,163.1902667,TNRC6C;CNOT6;CELF1;CNOT1;AGO2;HELZ;TNRC6A;TNRC6B,5.553953915,post-transcriptional gene silencing by RNA (GO:0035194)
44,innate immune response activating cell surface receptor signaling pathway (GO:0002220),35/119,4.68E-18,3.62E-16,0,0,8.167530225,325.9106883,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;BCL10;PSMA7;PSMB10;RELB;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;PSMB2;PSMB3;PSMD2;PSMD3;PSMB1;PSMD1;PSMB9;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2,17.32974469,innate immune response activating cell surface receptor signaling pathway (GO:0002220),positive regulation of ossification (GO:0045778),Nov-40,2.80E-06,0.000236384,0,0,7.275931802,93.01849361,TGFB2;BMPR2;ADGRV1;SOX11;PTN;ATP2B1;BMPR1B;ACVR2B;GPM6B;ACVR2A;BMPR1A,5.552198618,positive regulation of ossification (GO:0045778)
45,mitochondrial translational elongation (GO:0070125),30/89,1.61E-17,1.19E-15,0,0,9.928883453,383.9463965,MRPS16;MRPS35;MRPS36;MRPS11;MRPS34;MRPL38;MRPL16;MRPL39;MRPL17;MRPL14;MRPL58;MRPL15;MRPL12;MRPL57;MRPL41;MRPL20;MRPL2;MRPL40;MRPS28;GADD45GIP1;MRPS24;MRPS23;MRPS18A;MRPS21;MRPL28;MRPS7;MRPL43;MRPS18C;MRPL22;MRPL51,16.79401336,mitochondrial translational elongation (GO:0070125),positive regulation of cell population proliferation (GO:0008284),48/474,2.85E-06,0.000236384,0,0,2.198366671,28.06540664,HDAC4;YAP1;IRS1;CUL3;PDGFA;PTN;LAMC1;RBPJ;IGF1R;DPP4;EFNB2;PAK1;CCND2;RAB25;ERBB3;PDGFC;SOX4;NPM1;TGFB2;PRKCH;CSNK2A1;INSR;IGF2;HMGA2;SOX11;LAMB1;NAP1L1;MIF;MEIS2;PTK2;TGFBR1;FOXP1;VEGFA;TJP1;TIAM1;CNOT6;MEIS1;CDK6;GAREM1;GDNF;ID2;PHIP;SINHCAF;CDK13;TOX;FGFR2;EZH2;BMPR1A,5.544412314,positive regulation of cell population proliferation (GO:0008284)
46,mitochondrial translational termination (GO:0070126),30/89,1.61E-17,1.19E-15,0,0,9.928883453,383.9463965,MRPS16;MRPS35;MRPS36;MRPS11;MRPS34;MRPL38;MRPL16;MRPL39;MRPL17;MRPL14;MRPL58;MRPL15;MRPL12;MRPL57;MRPL41;MRPL20;MRPL2;MRPL40;MRPS28;GADD45GIP1;MRPS24;MRPS23;MRPS18A;MRPS21;MRPL28;MRPS7;MRPL43;MRPS18C;MRPL22;MRPL51,16.79401336,mitochondrial translational termination (GO:0070126),stress granule assembly (GO:0034063),21-Aug,4.31E-06,0.000349424,0,0,11.77853598,145.5081935,DDX6;DYNC1H1;ATXN2;DDX3X;YTHDF3;CSDE1;PRRC2C;UBAP2L,5.365132441,stress granule assembly (GO:0034063)
47,protein modification by small protein removal (GO:0070646),53/276,1.76E-17,1.27E-15,0,0,4.712455192,181.8002646,PSMD8;BABAM1;PSMD6;PSMD7;PSMD4;PSMD2;PSMD3;PSMD1;DDX58;ACTR5;PSMA5;PSMA3;PSMA4;RNF128;PSMA1;PSMA2;PSME1;PSME2;BIRC3;PSMB11;INO80E;PSMD12;VCP;PSMD11;PSMD14;PSMD13;GPS1;NEDD8;PSMA7;PSMB10;SNX3;PSMB6;PSMB4;PSMB5;PSMB2;STAMBPL1;UBB;PSMB3;PSMB1;UBC;MCRS1;TAF10;ADRM1;PSMB9;NFKBIA;PSMC5;COPS6;COPS5;PSMC3;TNIP1;PSMC4;PSMC1;PSMC2,16.7545045,protein modification by small protein removal (GO:0070646),regulation of BMP signaling pathway (GO:0030510),15/76,4.44E-06,0.000352044,0,0,4.728051926,58.27181331,BMPR2;NUMA1;SMURF2;CRIM1;SOX11;RBPJ;FSTL1;ACVR2B;ACVR2A;HIPK2;SMAD7;TWSG1;BMPR1B;TRIM33;BMPR1A,5.352548442,regulation of BMP signaling pathway (GO:0030510)
48,protein deubiquitination (GO:0016579),52/267,1.89E-17,1.34E-15,0,0,4.792562065,184.5377126,PSMD8;BABAM1;PSMD6;PSMD7;PSMD4;PSMD2;PSMD3;PSMD1;DDX58;ACTR5;PSMA5;PSMA3;PSMA4;RNF128;PSMA1;PSMA2;PSME1;PSME2;BIRC3;PSMB11;ENY2;INO80E;PSMD12;VCP;PSMD11;PSMD14;PSMD13;NEDD8;PSMA7;PSMB10;SNX3;PSMB6;PSMB4;PSMB5;PSMB2;STAMBPL1;UBB;PSMB3;PSMB1;UBC;MCRS1;TAF10;ADRM1;PSMB9;NFKBIA;PSMC5;COPS5;PSMC3;TNIP1;PSMC4;PSMC1;PSMC2,16.72251902,protein deubiquitination (GO:0016579),sympathetic nervous system development (GO:0048485),16-Jul,5.88E-06,0.000442874,0,0,14.87490209,179.1544689,FZD3;GDNF;NF1;CTNNB1;SOX11;GATA3;SOX4,5.23067626,sympathetic nervous system development (GO:0048485)
49,cytokine-mediated signaling pathway (GO:0019221),84/621,6.34E-17,4.40E-15,0,0,3.152911615,117.5935949,IFITM3;CIITA;IFITM1;ILK;IFI35;IFI30;IL18BP;ICAM1;PSMD8;PYCARD;PSMD6;PSMD7;PSMD4;PSMD2;CASP3;PSMD3;CFL1;PSMD1;TRIM25;TRIM26;JUNB;JAK3;B2M;IL13RA1;EIF5A;IL15RA;IFNGR2;TALDO1;FOS;PSMA5;PSMA3;PSMA4;PSMA1;IFI27;PSMA2;IRF1;CSNK2B;PSME1;PSME2;IRF8;UBE2V1;PPIA;CD44;BIRC3;PSMB11;PSMD12;CTF1;PSMD11;PSMD14;PSMD13;PSMA7;PSMB10;PSMB6;CDC42;SOCS3;PSMB4;PSMB5;SOCS1;PSMB2;UBB;PSMB3;PSMB1;UBC;GBP2;MCL1;CCL25;EGR1;HSPA8;VCAM1;STAT1;STAT3;ISG15;SOD2;PSMB9;ISG20;NFKBIA;CXCL10;PSMC5;CXCL12;PSMC3;PSMC4;PSMC1;PSMC2;XAF1,16.19780559,cytokine-mediated signaling pathway (GO:0019221),mesenchymal cell differentiation (GO:0048762),Dec-51,5.94E-06,0.000442874,0,0,5.905014014,71.05676113,DDX17;GSK3B;TGFB2;ROCK1;FBXL17;HMGA2;CTNNB1;RBPJ;ISL1;TGFBR1;FGFR2;LRP6,5.225992552,mesenchymal cell differentiation (GO:0048762)
50,positive regulation of Wnt signaling pathway (GO:0030177),38/153,9.56E-17,6.50E-15,0,0,6.486757661,239.2712512,PSMB11;PSMD12;VCP;PSMD11;PSMD14;PSMD13;ILK;NRARP;EGFR;PSMA7;PSMB10;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;PSMB2;PSMB3;PSMD2;PSMD3;PSMB1;PSMD1;DAPK3;PSMB9;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2,16.01943367,positive regulation of Wnt signaling pathway (GO:0030177),regulation of epithelial cell migration (GO:0010632),Dec-51,5.94E-06,0.000442874,0,0,5.905014014,71.05676113,MACF1;TGFB2;BMPR2;RAB25;PTN;MCC;DOCK1;RREB1;RTN4;CLASP1;SASH1;PTK2,5.225992552,regulation of epithelial cell migration (GO:0010632)
51,translational termination (GO:0006415),30/96,1.76E-16,1.17E-14,0,0,8.872539831,321.8801778,MRPS16;MRPS35;MRPS36;MRPS11;MRPS34;MRPL38;MRPL16;MRPL39;MRPL17;MRPL14;MRPL58;MRPL15;MRPL12;MRPL57;MRPL41;MRPL20;MRPL2;MRPL40;MRPS28;GADD45GIP1;MRPS24;MRPS23;MRPS18A;MRPS21;MRPL28;MRPS7;MRPL43;MRPS18C;MRPL22;MRPL51,15.75544181,translational termination (GO:0006415),"Wnt signaling pathway, calcium modulating pathway (GO:0007223)",Oct-36,7.22E-06,0.000527407,0,0,7.371406371,87.26862845,TNRC6C;PPP3CA;PPP3CB;FZD3;FZD6;AGO2;CTNNB1;NLK;TNRC6A;TNRC6B,5.14152685,"Wnt signaling pathway, calcium modulating pathway (GO:0007223)"
52,translational elongation (GO:0006414),31/104,2.48E-16,1.62E-14,0,0,8.294626574,298.0411171,MRPS16;MRPS35;MRPS36;MRPS11;MRPS34;MRPL16;MRPL38;MRPL17;MRPL39;MRPL14;MRPL58;MRPL15;MRPL12;MRPL57;MRPL41;MRPL20;MRPL2;MRPL40;MRPS28;GADD45GIP1;MRPS24;MRPS23;MRPS18A;MRPL28;MRPS21;MRPS7;MRPL43;MRPS18C;MRPL22;MRPL51;EEF1D,15.60499576,translational elongation (GO:0006414),glycolytic process (GO:0006096),29-Sep,7.62E-06,0.000545738,0,0,8.618567104,101.5717005,LDHA;PFKL;TPI1;PKM;PGAM1;PGK1;ENO1;ALDOA;HK2,5.118255565,glycolytic process (GO:0006096)
53,protein-DNA complex assembly (GO:0065004),36/143,3.88E-16,2.49E-14,0,0,6.593903905,233.9869152,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;CETN2;PSMA7;PSMB10;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;UBB;PSMB2;PSMB3;PSMD2;PSMD3;UBC;PSMB1;PSMD1;PSMB9;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2,15.4110869,protein-DNA complex assembly (GO:0065004),positive regulation of signal transduction (GO:0009967),30/252,9.84E-06,0.000691518,0,0,2.616049039,30.16152789,YAP1;MACF1;KANK1;MAML2;CITED2;IRS1;GATA3;RBPJ;ROBO1;CUX2;CDH3;ZMIZ1;GRB10;EP300;SASH1;TRIM44;CREBBP;ZRANB1;MBD5;TGFB2;JAG1;CSNK2A1;LMO3;IGF2;TGFBR1;SMARCA4;ASXL1;ASXL2;PHIP;FGFR2,5.00716345,positive regulation of signal transduction (GO:0009967)
54,negative regulation of canonical Wnt signaling pathway (GO:0090090),38/165,1.41E-15,8.87E-14,0,0,5.870103295,200.7359386,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;TMEM131L;PSMA7;PSMB10;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;PSMB2;PSMB3;PSMD2;PSMD3;PSMB1;PSMD1;IGFBP2;KREMEN2;TLE5;PSMB9;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2;SNAI2,14.85127366,negative regulation of canonical Wnt signaling pathway (GO:0090090),cellular response to organic substance (GO:0071310),19/123,1.12E-05,0.000773454,0,0,3.519015134,40.11237514,NCOA2;NFAT5;URI1;SMAD3;BMPR2;IGFBP5;PTPN12;PTPN13;ACVR2B;PTPN14;TGFBR1;ACVR2A;CTNNB1;SLIT3;SLIT2;BMPR1B;PTPN4;MAP2K5;BMPR1A,4.950414396,cellular response to organic substance (GO:0071310)
55,T cell receptor signaling pathway (GO:0050852),37/158,1.88E-15,1.16E-13,0,0,5.994722072,203.2605683,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;PIK3R2;BCL10;PSMA7;PSMB10;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;PSMB2;PSMB3;PSMD2;PSMD3;PSMB1;PSMD1;EIF2B4;PSMB9;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2;RBCK1,14.72544384,T cell receptor signaling pathway (GO:0050852),ephrin receptor signaling pathway (GO:0048013),15/82,1.18E-05,0.000790736,0,0,4.303280552,48.84206594,EPHA5;EPHA4;ROCK1;ARHGEF28;ITSN1;AP2B1;EFNA5;PTK2;EFNB2;TIAM1;PAK1;CHN1;NCK2;FYN;EPHB2,4.929225383,ephrin receptor signaling pathway (GO:0048013)
56,mitochondrial translation (GO:0032543),30/105,2.73E-15,1.66E-13,0,0,7.804123711,261.7207556,MRPS16;MRPS35;MRPS36;MRPS11;MRPS34;MRPL16;MRPL38;MRPL17;MRPL39;MRPL14;MRPL58;MRPL15;MRPL12;MRPL57;MRPL41;MRPL20;MRPL2;MRPL40;MRPS28;GADD45GIP1;MRPS24;MRPS23;MRPS18A;MRPL28;MRPS21;MRPS7;MRPL43;MRPS18C;MRPL22;MRPL51,14.56459228,mitochondrial translation (GO:0032543),positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway (GO:0090100),16/92,1.19E-05,0.000790736,0,0,4.048780488,45.9143266,CDKN1C;CREBBP;TGFB2;BMPR2;NUMA1;CITED2;SOX11;RBPJ;ACVR2B;TGFBR1;ACVR2A;HIPK2;TWSG1;EP300;BMPR1B;BMPR1A,4.92502341,positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway (GO:0090100)
57,proteasomal ubiquitin-independent protein catabolic process (GO:0010499),15/22,3.38E-15,2.02E-13,0,0,41.31907179,1376.794367,PSMB11;PSMA7;PSMB10;PSMB9;PSMA5;PSMB6;PSMA3;PSMB4;PSMA4;PSMB5;PSMA1;PSMB2;PSMA2;PSMB3;PSMB1,14.47114299,proteasomal ubiquitin-independent protein catabolic process (GO:0010499),insulin receptor signaling pathway (GO:0008286),14/73,1.30E-05,0.000850276,0,0,4.558290645,51.27445289,GSK3B;C2CD5;IRS1;INSR;IRS4;IGF2;PIK3C2A;IGF1R;GRB14;PIK3CA;APC;GRB10;PHIP;APPL1,4.885211077,insulin receptor signaling pathway (GO:0008286)
58,proteasomal protein catabolic process (GO:0010498),42/205,3.77E-15,2.21E-13,0,0,5.066498457,168.2693959,PSMB11;PSMD12;VCP;PSMD11;PSMD14;PSMD13;UBE2D3;PSMA7;PSMB10;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;PSMB2;PSMB3;PSMD2;PSMD3;PSMB1;PSMD1;UBE2A;PSMB9;PSMA5;SPSB2;NSFL1C;PSMA3;PSMC5;CDC34;PSMA4;IFI27;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2;STUB1;RBCK1,14.42386112,proteasomal protein catabolic process (GO:0010498),canonical glycolysis (GO:0061621),24-Aug,1.36E-05,0.000850276,0,0,9.568548387,107.1965038,PFKL;TPI1;PKM;PGAM1;PGK1;ENO1;ALDOA;HK2,4.865403631,canonical glycolysis (GO:0061621)
59,cholesterol biosynthetic process (GO:0006695),18/35,6.65E-15,3.83E-13,0,0,20.46807236,668.1633878,IDI1;FDPS;MVK;HMGCS1;INSIG1;MSMO1;HMGCR;LSS;ACAT2;TM7SF2;ACLY;SQLE;NSDHL;PMVK;SC5D;MVD;DHCR7;FDFT1,14.17718617,cholesterol biosynthetic process (GO:0006695),glucose catabolic process to pyruvate (GO:0061718),24-Aug,1.36E-05,0.000850276,0,0,9.568548387,107.1965038,PFKL;TPI1;PKM;PGAM1;PGK1;ENO1;ALDOA;HK2,4.865403631,glucose catabolic process to pyruvate (GO:0061718)
60,negative regulation of Wnt signaling pathway (GO:0030178),39/191,4.09E-14,2.32E-12,0,0,5.032258065,155.1269162,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;TMEM131L;PSMA7;PSMB10;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;RNF213;PSMB5;PSMD4;PSMB2;PSMB3;PSMD2;PSMD3;PSMB1;PSMD1;IGFBP2;KREMEN2;TLE5;PSMB9;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2;SNAI2,13.38777996,negative regulation of Wnt signaling pathway (GO:0030178),cellular response to transforming growth factor beta stimulus (GO:0071560),18/114,1.39E-05,0.000850276,0,0,3.609470468,40.36169852,ITGB1;JUN;TGFB2;SMAD3;ZFYVE9;USP9X;PTPRK;NLK;CBL;PTK2;TGFBR1;SMAD7;TWSG1;ZMIZ1;PARD3;SOX5;BMPR1A;APPL1,4.856353058,cellular response to transforming growth factor beta stimulus (GO:0071560)
61,sterol biosynthetic process (GO:0016126),18/38,4.27E-14,2.38E-12,0,0,17.39511202,535.5158929,IDI1;FDPS;MVK;HMGCS1;INSIG1;MSMO1;HMGCR;LSS;ACAT2;TM7SF2;ACLY;SQLE;NSDHL;PMVK;SC5D;MVD;DHCR7;FDFT1,13.36993962,sterol biosynthetic process (GO:0016126),histone modification (GO:0016570),18/114,1.39E-05,0.000850276,0,0,3.609470468,40.36169852,HDAC4;CREBBP;EYA1;USP3;USP22;PRDM5;EYA4;HUWE1;EHMT1;BAZ1B;RPS6KA5;KAT6B;KAT6A;NSD1;EP300;TBL1X;RCOR1;EZH2,4.856353058,histone modification (GO:0016570)
62,proteasome-mediated ubiquitin-dependent protein catabolic process (GO:0043161),52/321,5.27E-14,2.89E-12,0,0,3.819475162,116.7737075,UBE2D3;PSMD8;PSMD6;PSMD7;PSMD4;PSMD2;PSMD3;PSMD1;TRIM25;FBXO6;SEC61B;PSMA5;PSMA3;CDC34;PSMA4;IFI27;PSMA1;SELENOS;PSMA2;PSME1;PSME2;RBCK1;PSMB11;PSMD12;VCP;PSMD11;PSMD14;PSMD13;DERL2;PSMA7;PSMB10;PSMB6;PSMB4;PSMB5;PSMB2;UBB;PSMB3;PSMB1;UBC;HSPA5;FBXL15;UBE2A;PSMB9;FBXO31;SPSB2;NSFL1C;PSMC5;PSMC3;PSMC4;PSMC1;PSMC2;STUB1,13.27778677,proteasome-mediated ubiquitin-dependent protein catabolic process (GO:0043161),nervous system development (GO:0007399),44/447,1.50E-05,0.000900448,0,0,2.123892978,23.59342335,HDAC4;YAP1;CNTFR;CHD7;SLC2A1;PTN;EFNA5;NR2C2;ROBO1;ATXN1;ERBB3;FLRT3;PDGFC;ADAM23;IGF2BP1;EP300;MBP;IGF2BP3;IGF2BP2;JARID2;EPHB2;ASIC2;TEAD1;GPM6B;FARP1;MBD5;RBFOX2;JAG1;SEMA6A;ADGRV1;ST8SIA2;DYRK1A;FBXL17;CRIM1;GRHL2;TGFBR1;VEGFA;APC;GDNF;SCN8A;NF1;WDPCP;APBA2;FGF12,4.8243926,nervous system development (GO:0007399)
63,ubiquitin-dependent protein catabolic process (GO:0006511),55/354,5.89E-14,3.18E-12,0,0,3.640193945,110.8903869,PPP1R11;UBE2D3;UBE2L6;UBE2L3;PSMD8;PSMD6;PSMD7;PSMD4;PSMD2;PSMD3;PSMD1;TRIM25;ELOC;KCTD6;PSMA5;PSMA3;CDC34;PSMA4;IFI27;RNF128;PSMA1;PSMA2;PSME1;PSME2;RBCK1;PSMB11;PSMD12;VCP;PSMD11;PSMD14;PSMD13;NEDD8;PSMA7;PSMB10;PSMB6;PSMB4;RNF213;PSMB5;PSMB2;PSMB3;PSMB1;MVB12A;XBP1;UBE2I;ADRM1;UBE2A;PSMB9;SPSB2;NSFL1C;PSMC5;PSMC3;PSMC4;PSMC1;PSMC2;STUB1,13.22981244,ubiquitin-dependent protein catabolic process (GO:0006511),commissural neuron axon guidance (GO:0071679),8-May,1.53E-05,0.00090296,0,0,31.82077052,352.885618,GDNF;NFIB;NCAM1;EPHB2;VEGFA,4.816233993,commissural neuron axon guidance (GO:0071679)
64,secondary alcohol biosynthetic process (GO:1902653),17/34,6.97E-14,3.70E-12,0,0,19.31129196,585.0392713,IDI1;FDPS;MVK;HMGCS1;INSIG1;MSMO1;HMGCR;LSS;ACAT2;TM7SF2;ACLY;SQLE;NSDHL;PMVK;MVD;DHCR7;FDFT1,13.15703412,secondary alcohol biosynthetic process (GO:1902653),positive regulation of cell differentiation (GO:0045597),30/258,1.56E-05,0.000909387,0,0,2.546391753,28.18078299,YAP1;BMPR2;PTN;CPNE1;CD36;CDON;SOX5;MEF2A;TGFB2;PRKCH;SMAD3;LMO3;SUCO;SOX11;NPNT;ISL1;ACVR2B;TGFBR1;ACVR2A;TIAM1;REST;CREB1;GDNF;ID2;ASXL2;CTNNB1;TCF4;BMPR1B;EZH2;BMPR1A,4.806314087,positive regulation of cell differentiation (GO:0045597)
65,antigen receptor-mediated signaling pathway (GO:0050851),38/185,7.13E-14,3.73E-12,0,0,5.066075495,153.3617279,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;PIK3R2;BCL10;PSMA7;PSMB10;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;PSMB2;PSMB3;PSMD2;PSMD3;PSMB1;PSMD1;EIF2B4;PSMB9;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2;RBCK1;SPG21,13.14709033,antigen receptor-mediated signaling pathway (GO:0050851),sensory organ development (GO:0007423),Dec-56,1.66E-05,0.0009513,0,0,5.232609496,57.59210921,SMCHD1;TGFB2;MEIS1;CHD7;PBX3;ECE1;GATA3;BMPR1B;MEIS2;FREM2;PBX1;HIPK2,4.780011819,sensory organ development (GO:0007423)
66,post-translational protein modification (GO:0043687),54/345,7.34E-14,3.78E-12,0,0,3.669950524,110.9882714,TNC;PSMD8;PSMD6;PSMD7;PSMD4;PSMD2;PSMD3;PSMD1;FBXO6;ELOB;ELOC;WSB2;APLP2;IGFBP3;KCTD6;PSMA5;PTP4A2;PSMA3;PSMA4;PSMA1;PSMA2;PSME1;PSME2;GAS6;PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;GPS1;NEDD8;PSMA7;PSMB10;PSMB6;SOCS3;PSMB4;PSMB5;PSMB2;PSMB3;PSMB1;RBBP7;FBXL15;PSMB9;FBXO31;SPSB2;PSMC5;COPS6;COPS5;PSMC3;PSMC4;PSMC1;PSMC2;PNPLA2;UBE2M,13.13412633,post-translational protein modification (GO:0043687),positive regulation of cell motility (GO:2000147),27/221,1.69E-05,0.00095322,0,0,2.689958784,29.56022709,ITGB1;SEMA3C;SEMA3D;PDGFA;IGF1R;PPP3CA;PAK1;PDGFC;EPHB2;MAP4K4;CARMIL1;SEMA6A;INSR;LAMB1;ACTN4;SEMA4G;PLET1;PTK2;TGFBR1;VEGFA;TJP1;TIAM1;APC;NUMB;ITGA6;ROR2;PHPT1,4.772505656,positive regulation of cell motility (GO:2000147)
67,regulation of canonical Wnt signaling pathway (GO:0060828),44/253,3.81E-13,1.93E-11,0,0,4.138075314,118.3308821,PSMB11;PSMD12;VCP;PSMD11;PSMD14;PSMD13;ILK;NRARP;TMEM131L;EGFR;PSMA7;PSMB10;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;PSMB2;PSMB3;PSMD2;PSMD3;PSMB1;PSMD1;DAPK3;IGFBP2;KREMEN2;PPP1CA;PSMB9;TLE5;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2;SNAI2,12.41892552,regulation of canonical Wnt signaling pathway (GO:0060828),positive regulation of protein catabolic process (GO:0045732),15/85,1.85E-05,0.000997536,0,0,4.118201595,44.88791245,GSK3B;HSP90AA1;CSNK2A1;SMURF2;FAF1;PLK2;HUWE1;NEDD4L;DDB1;ITCH;APC;NEDD4;GPC3;VGLL4;SH3D19,4.733758712,positive regulation of protein catabolic process (GO:0045732)
68,regulation of mitotic cell cycle (GO:0007346),36/178,5.30E-13,2.65E-11,0,0,4.959441295,140.186637,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;SRA1;PSMA7;PSMB10;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;PSMB5;PSMD4;PSMB2;PSMB3;PSMD2;PSMD3;PSMB1;PSMD1;DAPK3;ASNS;PSMB9;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2,12.27603661,regulation of mitotic cell cycle (GO:0007346),gene silencing by miRNA (GO:0035195),Sep-32,1.86E-05,0.000997536,0,0,7.493221603,81.60801934,TNRC6C;CNOT6;CNOT1;AGO2;DICER1;PUM1;TNRC6A;PUM2;TNRC6B,4.729863116,gene silencing by miRNA (GO:0035195)
69,protein polyubiquitination (GO:0000209),48/314,4.39E-12,2.16E-10,0,0,3.551020408,92.865796,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;UBE2D3;UBE2L6;PSMA7;PSMB10;UBE2L3;PSMD8;PSMB6;PSMD6;PSMB4;PSMD7;RNF213;PSMB5;PSMD4;PSMB2;UBB;PSMB3;PSMD2;PSMD3;PSMB1;UBC;PSMD1;FBXO6;FBXL15;UBE2A;PSMB9;FBXO31;PSMA5;PSMA3;PSMC5;CDC34;PSMA4;IFI27;PSMA1;PSMC3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2;STUB1;RBCK1;UBE2V1,11.3576094,protein polyubiquitination (GO:0000209),regulation of cell morphogenesis (GO:0022604),Sep-32,1.86E-05,0.000997536,0,0,7.493221603,81.60801934,NTNG1;MACF1;ZRANB1;SPARC;ZMYM4;PHIP;EFNA5;MYO9A;SH3D19,4.729863116,regulation of cell morphogenesis (GO:0022604)
70,MAPK cascade (GO:0000165),45/303,5.55E-11,2.70E-09,0,0,3.422987946,80.83063505,PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;PIK3R2;EGFR;PSMA7;PSMB10;ZFP36L1;PSMD8;PSMB6;PSMD6;PSMB4;ZFP36;PSMD7;PSMB5;PSMD4;PSMB2;FNTA;UBB;PSMB3;PSMD2;PSMD3;PSMB1;UBC;PSMD1;NRTN;JAK3;MAP2K2;PSMB9;PSMA5;PSMA3;PSMC5;PSMA4;PSMA1;PSMC3;TAOK3;PSMA2;PSMC4;PSMC1;PSMC2;PSME1;PSME2;CALM1,10.25545498,MAPK cascade (GO:0000165),glycolytic process through glucose-6-phosphate (GO:0061620),25-Aug,1.92E-05,0.000997536,0,0,9.005218216,97.81495938,PFKL;TPI1;PKM;PGAM1;PGK1;ENO1;ALDOA;HK2,4.717320123,glycolytic process through glucose-6-phosphate (GO:0061620)
71,protein ubiquitination (GO:0016567),57/525,3.17E-08,1.52E-06,0,0,2.393534002,41.3313497,UBE2D3;UBE2L6;UBE2L3;PSMD8;PSMD6;PSMD7;PSMD4;PSMD2;PSMD3;PSMD1;TRIM25;ELOB;FBXO6;TRIM26;ELOC;PSMA5;PSMA3;PSMA4;CDC34;PSMA1;SELENOS;PSMA2;PSME1;PSME2;RBCK1;UBE2V1;PSMB11;PSMD12;VCP;PSMD11;PSMD14;PSMD13;NEDD8;BCL10;PSMA7;PSMB10;PSMB6;PSMB4;RNF213;PSMB5;PSMB2;UBB;PSMB3;PSMB1;UBC;FBXL15;ISG15;UBE2A;PSMB9;FBXO31;SPSB2;PSMC5;PSMC3;PSMC4;PSMC1;PSMC2;STUB1,7.49936165,protein ubiquitination (GO:0016567),cardiac right ventricle morphogenesis (GO:0003215),13-Jun,1.95E-05,0.000997536,0,0,16.37798218,177.6187517,TGFB2;JAG1;GATA3;ISL1;SOX4;BMPR1A,4.709911324,cardiac right ventricle morphogenesis (GO:0003215)
72,cholesterol metabolic process (GO:0008203),18/77,3.26E-08,1.54E-06,0,0,5.884531741,101.4396786,IDI1;FDPS;MVK;HMGCS1;INSIG1;MSMO1;HMGCR;LSS;ACAT2;TM7SF2;ACLY;SQLE;NSDHL;SNX17;PMVK;MVD;DHCR7;FDFT1,7.486524778,cholesterol metabolic process (GO:0008203),positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213),13-Jun,1.95E-05,0.000997536,0,0,16.37798218,177.6187517,TNRC6C;CNOT1;AGO2;PABPC1;TNRC6A;TNRC6B,4.709911324,positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)
73,mitochondrial gene expression (GO:0140053),13/42,7.44E-08,3.47E-06,0,0,8.616252664,141.4227136,MRPS28;MRPS16;MRPS24;MRPS11;MRPS34;MRPL16;MRPS18A;MRPS21;MRPL12;MRPS7;MRPL57;MRPL2;MRPL51,7.128284944,mitochondrial gene expression (GO:0140053),ERBB signaling pathway (GO:0038127),13/66,1.95E-05,0.000997536,0,0,4.708589016,51.05454274,HSP90AA1;BRAF;PTPN12;PIK3C2A;CBL;PTK2;RPS6KA5;GAREM1;PIK3CA;ERBB3;KIF16B;NCK2;PLCE1,4.708991614,ERBB signaling pathway (GO:0038127)
74,"mitochondrial electron transport, ubiquinol to cytochrome c (GO:0006122)",12-Jul,4.86E-07,2.23E-05,0,0,26.78046324,389.3212736,UQCRB;UQCRQ;UQCRC1;UQCRFS1;CYC1;UQCR10;UQCRC2,6.313560721,"mitochondrial electron transport, ubiquinol to cytochrome c (GO:0006122)",positive regulation of cell projection organization (GO:0031346),18/117,2.00E-05,0.001009309,0,0,3.499537123,37.85629496,CARMIL1;TENM3;CAMK1D;STMN2;PTN;CBFA2T2;ROBO1;PTPRD;GRIP1;TIAM1;CUX2;CUX1;EP300;ABL2;ITGA6;ROR2;SLIT2;TOX,4.697987027,positive regulation of cell projection organization (GO:0031346)
75,regulation of lipid metabolic process (GO:0019216),18/92,5.76E-07,2.61E-05,0,0,4.688005725,67.35165087,IDI1;FDPS;MVK;HMGCS1;EDF1;HMGCR;LSS;TM7SF2;SQLE;SIN3B;FASN;PMVK;PSAP;SC5D;MVD;THRSP;DHCR7;FDFT1,6.23942291,regulation of lipid metabolic process (GO:0019216),enzyme linked receptor protein signaling pathway (GO:0007167),20/140,2.18E-05,0.001081725,0,0,3.210884354,34.46820327,EPHA5;EPHA4;TRIO;BMPR2;INSR;LMTK2;PTN;ACVR2B;PTK2;PTPRF;MTSS1;ACVR2A;IGF1R;PTPRD;ERBB3;FYN;ROR2;EPHB2;FGFR2;MPZL1,4.662064663,enzyme linked receptor protein signaling pathway (GO:0007167)
76,cellular respiration (GO:0045333),Dec-42,6.28E-07,2.81E-05,0,0,7.680161943,109.6814566,NDUFS8;UQCRB;NDUFA5;NDUFS7;MDH2;UQCRC1;UQCRFS1;ETFA;UQCR10;UQCRC2;MTLN;SDHB,6.202219654,cellular respiration (GO:0045333),positive regulation of developmental process (GO:0051094),23/177,2.61E-05,0.001281373,0,0,2.88092358,30.40002616,BMPR2;RIF1;TFRC;SMURF2;NUMA1;INSR;BNIP3;COBL;PTN;NR2C2;ISL1;RTN4;VEGFA;GRIP1;REST;GDNF;AGO2;DAG1;BMPR1B;RREB1;CLASP1;SOX5;BMPR1A,4.582753844,positive regulation of developmental process (GO:0051094)
77,antigen processing and presentation of peptide antigen via MHC class I (GO:0002474),Oct-33,3.01E-06,0.000133144,0,0,8.334211682,105.9453336,PDIA3;SEC13;ERAP1;TAP2;TAP1;TAPBPL;CALR;IFI30;B2M;TAPBP,5.52079495,antigen processing and presentation of peptide antigen via MHC class I (GO:0002474),positive regulation of phosphorylation (GO:0042327),29/253,2.82E-05,0.00136242,0,0,2.503420627,26.23028563,APP;TFRC;ZBTB20;EFNA5;IGF1R;FXR1;PAK1;CCND2;ERBB3;RB1CC1;EPHB2;FNIP1;EPHA5;EPHA4;HSP90AA1;ANGPT1;LIMCH1;LMO4;INSR;IGF2;LMTK2;MIF;PTK2;ACVR2A;VEGFA;ITGA6;ROR2;TNIK;FGFR2,4.550441179,positive regulation of phosphorylation (GO:0042327)
78,negative regulation of programmed cell death (GO:0043069),41/381,3.40E-06,0.00014824,0,0,2.346377967,29.54510519,RPL10;GSTP1;CIB1;PARK7;PHB2;EGFR;PRDX3;MIEN1;GRK5;UBB;PDCD10;ARHGDIA;CASP3;CFL1;BAG1;UBC;MCL1;CD74;BNIP3L;XBP1;HSPA5;GPX4;ANXA4;ANXA5;NME2;ASNS;PA2G4;NFKBIA;DNAJA1;PSMC5;KRT18;COPS5;BCL3;NAA38;TMBIM6;CIAPIN1;ATF5;GAS6;FXN;CD44;BIRC3,5.468546129,negative regulation of programmed cell death (GO:0043069),ATP-dependent chromatin remodeling (GO:0043044),Oct-42,3.18E-05,0.001518903,0,0,5.987373737,62.00613106,CECR2;PBRM1;SMARCC1;CHD8;SMARCAD1;CHD4;HNRNPC;ARID1A;GATAD2B;SMARCA4,4.497618112,ATP-dependent chromatin remodeling (GO:0043044)
79,aerobic respiration (GO:0009060),21-Aug,4.31E-06,0.000185715,0,0,11.77853598,145.5081935,NDUFS8;UQCRB;NDUFS7;MDH2;UQCRC1;UQCR10;UQCRC2;SDHB,5.365132441,aerobic respiration (GO:0009060),embryonic digestive tract development (GO:0048566),20-Jul,3.34E-05,0.001575194,0,0,10.29584011,106.1194284,TGFB2;NIPBL;ID2;SOX11;GLI3;FGFR2;GLI2,4.476281846,embryonic digestive tract development (GO:0048566)
80,cellular protein modification process (GO:0006464),84/1025,5.24E-06,0.000222846,0,0,1.759899577,21.39831801,UBE2D3;TNC;ILK;UBE2L6;PARK7;UBE2L3;PSMD8;PSMD6;PSMD7;DUSP10;SERP1;PSMD4;PSMD2;PSMD3;CDK20;PSMD1;FBXO6;ELOB;ELOC;JAK3;PARP3;WSB2;IGFBP3;APLP2;DAPK3;PARP9;DDOST;NRBP1;KCTD6;PSMA5;PTP4A2;PSMA3;PSMA4;CDC34;PSMA1;PSMA2;ADPRH;PSME1;PSME2;SGK3;GAS6;PSMB11;PSMD12;PSMD11;PSMD14;PSMD13;GPS1;NEDD8;PSMA7;PSMB10;PSMB6;SOCS3;PSMB4;PSMB5;PSMB2;GRK5;PSMB3;MKNK1;PSMB1;RBBP7;UBL4A;UBE2I;MCRS1;ISG15;FBXL15;PARP14;CLK3;PSMB9;FBXO31;PPP1CA;BCKDK;SPSB2;PSMC5;COPS6;COPS5;PSMC3;TAOK3;UBLCP1;PSMC4;PSMC1;CTH;PSMC2;PNPLA2;UBE2M,5.28051234,cellular protein modification process (GO:0006464),positive regulation of BMP signaling pathway (GO:0030513),27-Aug,3.60E-05,0.00167635,0,0,8.056451613,82.43522647,BMPR2;NUMA1;SOX11;RBPJ;BMPR1B;ACVR2B;ACVR2A;BMPR1A,4.44378812,positive regulation of BMP signaling pathway (GO:0030513)
81,regulation of apoptotic process (GO:0042981),64/742,1.51E-05,0.000635905,0,0,1.847767441,20.50622299,MTCH2;SRA1;CIB1;PARK7;PHB2;PYCARD;ARHGDIA;CASP3;GPER1;CFL1;JAK3;PHLDA3;BOK;BNIP3L;ACTN3;ANXA4;IGFBP3;DAPK3;ANXA5;ARHGEF16;NME2;NME1;BIN1;TMBIM6;NAA38;ATF5;GAS6;FXN;PPIA;CD44;ATF4;BIRC3;VCP;RPL10;GSTP1;BCL10;OMA1;EGFR;PRDX3;MIEN1;GRK5;UBB;PDCD10;BAG1;UBC;SAP18;BAK1;MCL1;CD74;XBP1;GADD45B;HSPA5;STAT1;GZMA;ASNS;PA2G4;DNAJA1;NFKBIA;CXCL10;COPS5;KRT18;BCL3;CIAPIN1;CALR,4.819729633,regulation of apoptotic process (GO:0042981),negative regulation of translation (GO:0017148),15/90,3.72E-05,0.001691496,0,0,3.842639594,39.18921171,FTO;DDX6;DDX3X;IGFBP5;ROCK1;YTHDF3;CELF1;DAPK1;PUM1;FXR1;CNOT1;AGO2;IGF2BP1;IGF2BP3;IGF2BP2,4.42915813,negative regulation of translation (GO:0017148)
82,negative regulation of apoptotic process (GO:0043066),46/485,2.48E-05,0.001027583,0,0,2.038667068,21.62139276,BEX3;BHLHB9;RPL10;GSTP1;MAZ;CIB1;PARK7;PHB2;EGFR;PRDX3;RNF213;MIEN1;GRK5;UBB;PDCD10;ARHGDIA;CASP3;CFL1;BAG1;UBC;SFN;MCL1;BNIP3L;CD74;XBP1;HSPA5;ANXA4;ANXA5;NME2;ASNS;PA2G4;SOD2;DNAJA1;NFKBIA;COPS5;KRT18;BCL3;SNAI2;TMBIM6;NAA38;CIAPIN1;ATF5;GAS6;FXN;CD44;BIRC3,4.605975991,negative regulation of apoptotic process (GO:0043066),"regulation of mRNA splicing, via spliceosome (GO:0048024)",15/90,3.72E-05,0.001691496,0,0,3.842639594,39.18921171,DDX17;RBM39;TIA1;RBFOX2;KHDRBS3;CELF1;CELF2;PRDX6;FXR1;REST;FAM172A;PCBP4;TRA2B;TRA2A;RBM5,4.42915813,"regulation of mRNA splicing, via spliceosome (GO:0048024)"
83,translation (GO:0006412),26/214,2.65E-05,0.001085406,0,0,2.671108393,28.15023846,MRPS16;RPL10;MRPS36;MRPS11;MRPS34;MRPL16;MRPL57;MRPL41;MRPL2;RPL35;RPL38;RPS2;MRPS28;MRPS24;MRPS18A;MRPL28;MRPS21;MRPS7;MRPL43;MRPS18C;MRPL51;COPS5;TNIP1;PPA1;EEF1D;RPL22L1,4.5769364,translation (GO:0006412),regulation of cell-cell adhesion (GO:0022407),Oct-43,3.96E-05,0.00176407,0,0,5.805632078,58.85128863,DPP4;MAGI1;AFDN;TENM3;JAG1;CITED2;EFNA5;MDGA1;PTK2;SMAD7,4.40241296,regulation of cell-cell adhesion (GO:0022407)
84,interferon-gamma-mediated signaling pathway (GO:0060333),13/68,2.73E-05,0.001106457,0,0,4.536888643,47.67181231,CIITA;VCAM1;STAT1;IFNGR2;IFI30;ICAM1;IRF1;TRIM25;IRF8;TRIM26;GBP2;B2M;CD44,4.563392813,interferon-gamma-mediated signaling pathway (GO:0060333),negative regulation of macromolecule metabolic process (GO:0010605),24/194,3.98E-05,0.00176407,0,0,2.723722276,27.59785762,RB1;YAP1;APP;TGFB2;CITED2;CELF1;SOX11;DICER1;MIF;RUNX1;ROBO1;VEGFA;FOXP1;TNRC6C;ATXN2;REST;ID2;AGO2;CPNE1;TNRC6A;BMPR1A;PICALM;RBMS3;TNRC6B,4.400447647,negative regulation of macromolecule metabolic process (GO:0010605)
85,isopentenyl diphosphate biosynthetic process (GO:0009240),5-Apr,2.98E-05,0.001193648,0,0,76.30120482,795.0520127,IDI1;MVK;PMVK;MVD,4.525311268,isopentenyl diphosphate biosynthetic process (GO:0009240),negative regulation of BMP signaling pathway (GO:0030514),Nov-52,4.22E-05,0.001834565,0,0,5.143135466,51.80132734,BMPR2;SMURF2;CRIM1;BMPR1B;FSTL1;ACVR2B;ACVR2A;TRIM33;HIPK2;SMAD7;BMPR1A,4.374185897,negative regulation of BMP signaling pathway (GO:0030514)
86,regulation of response to interferon-gamma (GO:0060330),14-Jun,3.27E-05,0.00129255,0,0,14.32997988,148.0088508,SOCS3;SOCS1;STAT1;IFNGR2;CDC37;PARP9,4.485660671,regulation of response to interferon-gamma (GO:0060330),protein ubiquitination (GO:0016567),48/525,4.23E-05,0.001834565,0,0,1.957930342,19.71575338,UHRF2;UBE3C;TNKS;CUL3;RNF38;MYCBP2;NEDD4L;UBR2;UBE3A;HIF3A;CBL;SH3RF1;FBXL20;NPEPPS;ZNRF1;ZNRF3;TNKS2;TRIM24;ARIH1;BTRC;TRIM44;SASH1;RNF43;SMURF2;USP9X;FBXW11;USP22;FBXL17;HUWE1;RC3H1;UBE2E2;UBE2G1;LMO7;UBE4B;KLHL24;FBXO11;MIB1;DDB1;ITCH;KLHL7;NEDD4;PSME4;WAC;CTNNB1;TRIP12;DZIP3;TRIM33;FBXL7,4.373211199,protein ubiquitination (GO:0016567)
87,negative regulation of viral life cycle (GO:1903901),20-Jul,3.34E-05,0.001305586,0,0,10.29584011,106.1194284,IFITM3;SNX3;CIITA;IFITM1;TRIM26;PPIA;LY6E,4.476281846,negative regulation of viral life cycle (GO:1903901),regulation of cell-substrate junction assembly (GO:0090109),21-Jul,4.79E-05,0.002053151,0,0,9.559919436,95.07877309,MACF1;ROCK1;LIMCH1;EFNA5;PTK2;CLASP1;GPM6B,4.31930277,regulation of cell-substrate junction assembly (GO:0090109)
88,acetyl-CoA metabolic process (GO:0006084),15-Jun,5.22E-05,0.002016241,0,0,12.7370892,125.6005414,ACLY;MVK;HMGCS1;PMVK;MVD;ACAT1,4.282581459,acetyl-CoA metabolic process (GO:0006084),cardiac ventricle morphogenesis (GO:0003208),Oct-44,4.90E-05,0.002072911,0,0,5.634581105,55.920711,TGFB2;JAG1;SOX11;GATA3;RBPJ;ISL1;SOX4;FGFR2;SMAD7;BMPR1A,4.310179542,cardiac ventricle morphogenesis (GO:0003208)
89,negative regulation of intrinsic apoptotic signaling pathway (GO:2001243),Dec-64,6.75E-05,0.002580418,0,0,4.425724073,42.50019455,DNAJA1;XBP1;CXCL12;SELENOS;NDUFS3;SNAI2;TMBIM6;PARK7;SOD2;YBX3;PPIA;MCL1,4.1705266,negative regulation of intrinsic apoptotic signaling pathway (GO:2001243),regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211),15-Jun,5.22E-05,0.002137284,0,0,12.7370892,125.6005414,TNRC6C;CNOT1;AGO2;PABPC1;TNRC6A;TNRC6B,4.282581459,regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)
90,modification-dependent protein catabolic process (GO:0019941),24/201,7.05E-05,0.002663358,0,0,2.615031953,25.00018338,XBP1;PSMD11;UBE2I;PPP1R11;PSMD14;PSMD13;ADRM1;UBE2L6;NEDD8;ISG15;UBE2A;KCTD6;UBE2L3;SPSB2;CDC34;RNF213;RNF128;UBB;PSMD3;PSMC2;UBC;TRIM25;STUB1;ELOC,4.151934616,modification-dependent protein catabolic process (GO:0019941),embryonic limb morphogenesis (GO:0030326),Sep-36,5.22E-05,0.002137284,0,0,6.381769257,62.92711891,NIPBL;CREBBP;TGFB2;CTNNB1;ECE1;WDPCP;AFF3;GLI3;LRP6,4.282339177,embryonic limb morphogenesis (GO:0030326)
91,postreplication repair (GO:0006301),Oct-46,7.34E-05,0.002744936,0,0,5.320987654,50.65028417,VCP;RFC3;UBB;POLD2;UBC;TRIM25;UBE2L6;ISG15;UBE2A;UBE2V1,4.134033069,postreplication repair (GO:0006301),positive regulation of bone mineralization (GO:0030501),Sep-36,5.22E-05,0.002137284,0,0,6.381769257,62.92711891,BMPR2;ADGRV1;PTN;ATP2B1;BMPR1B;ACVR2B;GPM6B;ACVR2A;BMPR1A,4.282339177,positive regulation of bone mineralization (GO:0030501)
92,cellular response to type I interferon (GO:0071357),Dec-65,7.91E-05,0.00289244,0,0,4.341990681,41.00958129,IFITM3;ISG20;EGR1;IFITM1;IFI27;STAT1;IRF1;IRF8;ISG15;IFI35;GBP2;XAF1,4.101859302,cellular response to type I interferon (GO:0071357),positive regulation of intracellular signal transduction (GO:1902533),49/546,5.65E-05,0.002290031,0,0,1.918232846,18.76126085,ITGB1;APP;DDX3X;TFRC;IRS1;IGF1R;RPS15;RPTOR;AKAP13;CPNE1;EP300;HSP90AA1;ADGRV1;TNFRSF19;SOX11;ACTN4;MIF;TGFBR1;PIK3CA;RRAGD;ROR2;ANKRD17;NFAT5;ROCK1;PDGFA;GATA3;ATP2C1;CBL;RTN4;ERBB3;TSPAN6;PDGFC;FYN;FNIP1;TRIM44;SASH1;OSBPL8;TGFB2;ANGPT1;PLK2;INSR;IGF2;PUM1;PTK2;PUM2;VEGFA;NEDD4;TAB2;FGFR2,4.247613671,positive regulation of intracellular signal transduction (GO:1902533)
93,type I interferon signaling pathway (GO:0060337),Dec-65,7.91E-05,0.00289244,0,0,4.341990681,41.00958129,IFITM3;ISG20;EGR1;IFITM1;IFI27;STAT1;IRF1;IRF8;ISG15;IFI35;GBP2;XAF1,4.101859302,type I interferon signaling pathway (GO:0060337),regulation of osteoblast differentiation (GO:0045667),14/83,5.85E-05,0.002345056,0,0,3.895611018,37.96637896,YAP1;BMPR2;CRIM1;SUCO;SOX11;NPNT;ACVR2B;ACVR2A;PTK2;REST;CDK6;BMPR1B;FGFR2;BMPR1A,4.232606593,regulation of osteoblast differentiation (GO:0045667)
94,ATP synthesis coupled electron transport (GO:0042773),6-Apr,8.59E-05,0.003055927,0,0,38.14859438,357.1427907,NDUFB6;NDUFA12;NDUFS2;NDUFV1,4.065815419,ATP synthesis coupled electron transport (GO:0042773),regulation of nucleic acid-templated transcription (GO:1903506),41/430,5.99E-05,0.002372532,0,0,2.045433466,19.8889631,RB1;PLAG1;CHD7;JMJD1C;SIX1;RORA;PRDM2;NLK;NR2C2;SBNO1;ATXN1;RPS6KA5;ZMIZ1;NSD1;EP300;HMG20A;GPBP1L1;ERC1;RREB1;TEAD2;SOX4;NCOA2;CREBBP;ZFHX3;INSR;ATRX;IGF2;RFX3;HMGA2;SOX11;FOXN3;ACTN4;ACVR2B;TGFBR1;REST;DMTF1;KAT6B;ATF7;GTF2IRD1;SSBP2;EZH2,4.222902905,regulation of nucleic acid-templated transcription (GO:1903506)
95,vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane (GO:1990668),6-Apr,8.59E-05,0.003055927,0,0,38.14859438,357.1427907,TAP2;TAP1;CALR;TAPBP,4.065815419,vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane (GO:1990668),protein dephosphorylation (GO:0006470),19/139,6.43E-05,0.002520208,0,0,3.047230717,29.413783,MTMR3;EYA1;FBXW11;EYA4;PPM1H;PTPRK;PTPN12;PTPN13;PTPN14;PTPRF;PTPRD;PPP3CA;PPP3CB;UBASH3B;CTDSP2;RPRD1A;BTRC;PHPT1;PTPN4,4.192082857,protein dephosphorylation (GO:0006470)
96,neutrophil degranulation (GO:0043312),44/481,8.63E-05,0.003055927,0,0,1.9550664,18.2958026,CSTB;PSMD12;VCP;PSMD11;PSMD14;PSMD13;GSTP1;STXBP2;PYCARD;ALAD;PSMD6;SYNGR1;PSMD7;PSMD2;FTH1;NAPRT;PSMD3;PSMB1;LAMP2;PSAP;PSMD1;CAPN1;B2M;S100A11;GSDMD;CAP1;HSPA8;HGSNAT;DBNL;IDH1;NME2;PA2G4;TUBB4B;DDOST;PSMA5;ACLY;FABP5;PSMC3;PSMA2;PSMC2;CSNK2B;PPIA;CD44;VCL,4.064192456,neutrophil degranulation (GO:0043312),regulation of cell population proliferation (GO:0042127),63/764,6.73E-05,0.002611648,0,0,1.755134074,16.86072376,APP;COL18A1;BMPR2;TFRC;IRS1;CELF1;SIX1;PTPRK;IGF1R;CCND2;NCK2;ARID2;SOX4;RBM5;DIS3L2;PBRM1;RBFOX2;CSNK2A1;SOX11;TGFBR1;RUNX1;TIAM1;GAREM1;PHIP;SINHCAF;ROR2;HDAC4;BEX4;YAP1;CUL3;PDGFA;GATA3;PTN;DPP4;EFNB2;PAK1;RAB25;ERBB3;PDGFC;JUN;NPM1;TGFB2;JAG1;INSR;IGF2;NAP1L1;PTPN14;MEIS2;PTK2;VEGFA;TJP1;CNOT6;MEIS1;REST;CDK6;APC;GDNF;ID2;CTNNB1;CDK13;FGFR2;EZH2;BMPR1A,4.172056937,regulation of cell population proliferation (GO:0042127)
97,regulation of interferon-gamma-mediated signaling pathway (GO:0060334),23-Jul,9.26E-05,0.003245574,0,0,8.364048338,77.68174291,SOCS3;SOCS1;STAT1;IFNGR2;CDC37;PARP14;PARP9,4.033543438,regulation of interferon-gamma-mediated signaling pathway (GO:0060334),regulation of protein phosphorylation (GO:0001932),29/266,7.05E-05,0.002706428,0,0,2.36446397,22.60547036,APP;TFRC;PDGFA;HSPB1;EFNA5;LRP6;FXR1;PAK1;CCND2;NSD1;RB1CC1;PLCE1;FYN;SLIT2;EPHB2;FNIP1;NPM1;HSP90AA1;ANGPT1;LIMCH1;INSR;IGF2;PTPN13;PTK2;ACVR2A;VEGFA;CCDC88C;PHIP;TNIK,4.152074704,regulation of protein phosphorylation (GO:0001932)
98,cellular protein-containing complex assembly (GO:0034622),21/168,0.000101781,0.003532219,0,0,2.751057931,25.28961238,PSMD11;GPX4;PSMD13;SGIP1;STXBP1;POMP;ADRM1;TBCC;CLTA;COX7A2;OMA1;FKBP1A;EID2;PSMD4;BIN1;CSNK2B;CHMP2A;RPL38;SNX9;STXBP6;AP2M1,3.992332907,cellular protein-containing complex assembly (GO:0034622),pyruvate metabolic process (GO:0006090),Nov-55,7.30E-05,0.002773904,0,0,4.791708797,45.64400897,LDHA;PFKL;TPI1;PKM;PGAM1;BSG;PGK1;ENO1;ALDOA;SLC16A3;HK2,4.136925274,pyruvate metabolic process (GO:0006090)
99,neutrophil activation involved in immune response (GO:0002283),44/485,0.00010425,0.00358137,0,0,1.93691591,17.75902946,CSTB;PSMD12;VCP;PSMD11;PSMD14;PSMD13;GSTP1;STXBP2;PYCARD;ALAD;PSMD6;SYNGR1;PSMD7;PSMD2;FTH1;NAPRT;PSMD3;PSMB1;LAMP2;PSAP;PSMD1;CAPN1;B2M;S100A11;GSDMD;CAP1;HSPA8;HGSNAT;DBNL;IDH1;NME2;PA2G4;TUBB4B;DDOST;PSMA5;ACLY;FABP5;PSMC3;PSMA2;PSMC2;CSNK2B;PPIA;CD44;VCL,3.981922219,neutrophil activation involved in immune response (GO:0002283),mRNA destabilization (GO:0061157),Sep-38,8.26E-05,0.003093026,0,0,5.941020912,55.8545483,FTO;ROCK1;YTHDF3;CELF1;CNOT1;TUT4;RC3H1;PUM1;DIS3L2,4.083022509,mRNA destabilization (GO:0061157)
100,cellular response to interferon-gamma (GO:0071346),17/121,0.000108816,0.003700839,0,0,3.1421864,28.67512295,CCL25;CIITA;GBP7;VCAM1;STAT1;IFNGR2;DAPK3;IFI30;ICAM1;IRF1;TRIM25;IRF8;TRIM26;GBP2;B2M;CD44;GBP3,3.963306462,cellular response to interferon-gamma (GO:0071346),artery morphogenesis (GO:0048844),30-Aug,8.30E-05,0.003093026,0,0,6.956744868,65.3692318,TGFB2;BMPR2;JAG1;NF1;TGFBR1;SMAD7;VEGFA;BMPR1A,4.080859252,artery morphogenesis (GO:0048844)