drug_name ADR_name DE LT HO DS CA RI OT Abacavir Abdominal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Abacavir Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Abacavir Deep vein thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Abacavir Drug resistance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Abacavir Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Abacavir Hepatic enzyme increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Abacavir Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Abacavir Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Abacavir Pulmonary embolism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Abacavir Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Abemaciclib Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Balance disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Blood glucose decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Blood magnesium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Cardiac disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Cystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Abemaciclib Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Abemaciclib Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Full blood count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Hypoaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Interstitial lung disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Abemaciclib Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Abemaciclib Neutrophil count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Abemaciclib Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Pancytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Abemaciclib Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Platelet count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Abemaciclib Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Pneumonitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Abemaciclib Pneumothorax 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Pyrexia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Red blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Renal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Renal failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Abemaciclib Sepsis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Abemaciclib Swollen tongue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Abemaciclib Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abemaciclib White blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone Blood urine present 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone Cardiac arrest 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone Cerebrovascular accident 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Abiraterone Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Abiraterone Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone Febrile neutropenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Abiraterone Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone Lower respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone Myocardial infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone Prostate cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Abiraterone Sepsis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone acetate Acute hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Abiraterone acetate Alanine aminotransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Abiraterone acetate Aspartate aminotransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Abiraterone acetate Blood bilirubin increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Abiraterone acetate Cardiac failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone acetate Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone acetate Constipation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Abiraterone acetate Cough 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Abiraterone acetate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Abiraterone acetate Diarrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Abiraterone acetate Dyspepsia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Abiraterone acetate Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone acetate Fracture 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Abiraterone acetate Haematuria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Abiraterone acetate Hot flush 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Abiraterone acetate Hyperglycaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Abiraterone acetate Hypokalaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Abiraterone acetate Infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Abiraterone acetate Nasopharyngitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Abiraterone acetate Nocturia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Abiraterone acetate Oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Abiraterone acetate Pyrexia 1.0 1.0 1.0 1.0 0.0 0.0 0.0 Abiraterone acetate Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Abiraterone acetate Urinary tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Acalabrutinib Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acalabrutinib Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acalabrutinib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Acalabrutinib Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Acalabrutinib Drug resistance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acalabrutinib Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acalabrutinib Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Acarbose Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acarbose Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acarbose Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acarbose Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acarbose Drug-induced liver injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acarbose Hypoglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acarbose Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acarbose Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acarbose Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acebutolol Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acebutolol Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Abdominal pain upper 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Acidosis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Acute generalised exanthematous pustulosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Acute hepatic failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Aggression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Agitation 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Agranulocytosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Alanine aminotransferase increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Amylase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Acetaminophen Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Acetaminophen Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Apnoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Arrhythmia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Aspartate aminotransferase increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Asthenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Atelectasis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Balance disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Blood alkaline phosphatase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Blood bilirubin increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Blood creatine phosphokinase increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Blood creatinine increased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Blood disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Blood lactate dehydrogenase increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Blood pressure decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Body temperature decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Body temperature increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Brain oedema 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Cardiac disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Chills 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acetaminophen Coagulopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Confusional state 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Constipation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Acetaminophen Coordination abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Acetaminophen Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Depressed level of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Dermatitis exfoliative 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Diarrhoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Acetaminophen Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Acetaminophen Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Drug eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Drug hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Acetaminophen Drug interaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Drug-induced liver injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acetaminophen Dyskinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Acetaminophen Dyspepsia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Dysphoria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Dystonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Dysuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Electrolyte imbalance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Encephalopathy 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Eye disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Acetaminophen Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Acetaminophen Gamma-glutamyltransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Gastrointestinal disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Acetaminophen Gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Haematuria 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Haemoglobin decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Haemolytic anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Hallucination 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Acetaminophen Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acetaminophen Hepatic encephalopathy 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Hepatic enzyme increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Hepatic function abnormal 0.0 1.0 1.0 0.0 1.0 0.0 0.0 Acetaminophen Hepatic necrosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Hepatic steatosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Hepatitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Hepatitis acute 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Hepatitis fulminant 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Hepatocellular injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Hepatomegaly 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Hepatotoxicity 1.0 1.0 0.0 0.0 1.0 0.0 0.0 Acetaminophen Hyperglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Hyperreflexia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Acetaminophen Hypertension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Hypoaesthesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Hypoglycaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Hypomagnesaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Hypophosphataemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Hypothermia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Hypoxia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Ill-defined disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acetaminophen Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Acetaminophen Intentional self-injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Irritability 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Jaundice 1.0 1.0 1.0 0.0 1.0 0.0 0.0 Acetaminophen Lactic acidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Lethargy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Leukocytosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Leukopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Lip swelling 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Liver function test abnormal 0.0 1.0 1.0 0.0 1.0 0.0 0.0 Acetaminophen Liver function test increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Liver injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Malaise 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Acetaminophen Maternal drugs affecting foetus 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Acetaminophen Mental disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Mental status changes 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Metabolic acidosis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Muscle spasms 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Acetaminophen Mydriasis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Myoclonus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Nausea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Nervous system disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Neutropenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Nightmare 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acetaminophen Oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Oedema peripheral 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Oliguria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Acetaminophen Pain in extremity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Palpitations 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Pancreatitis acute 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Periorbital oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acetaminophen Peritonitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Pleural effusion 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Pneumothorax 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Premature baby 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Acetaminophen Prothrombin time prolonged 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Pyrexia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Rash generalised 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Rash maculo-papular 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Rash pustular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Renal failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Renal tubular necrosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Respiratory depression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Respiratory failure 1.0 1.0 1.0 0.0 1.0 0.0 0.0 Acetaminophen Seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Sepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Serotonin syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Shock 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Skin disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acetaminophen Somnolence 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Stevens-Johnson syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Suicide attempt 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Tachycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Toxic epidermal necrolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Transaminases increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Tremor 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Acetaminophen Unresponsive to stimuli 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Upper gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetaminophen Urinary retention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Acetaminophen Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Acetaminophen Vision blurred 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Acetaminophen Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acetaminophen Wheezing 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Acetazolamide Ataxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acetazolamide Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acetazolamide Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acetazolamide Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Acetazolamide Metabolic acidosis 0.0 1.0 1.0 0.0 1.0 0.0 0.0 Acetazolamide Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Acetazolamide Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acetylcysteine Anaphylactic reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acetylcysteine Anaphylactic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Acetylcysteine Anaphylactoid reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetylcysteine Bronchospasm 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acetylcysteine Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acetylcysteine Hepatitis fulminant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Acetylcysteine Hepatotoxicity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acetylcysteine Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acetylcysteine Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Acetylcysteine Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acetylcysteine Respiratory distress 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acetylcysteine Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acetylcysteine Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acitretin Abdominal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acitretin Acute myocardial infarction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acitretin Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Acitretin Asthenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acitretin Candida infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Acitretin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Acitretin Diabetes mellitus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Acitretin Dry skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acitretin Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acitretin Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acitretin Febrile neutropenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Acitretin Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Acitretin Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acitretin Hepatic enzyme increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acitretin Hyperlipidaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acitretin Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acitretin Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acitretin Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acitretin Nail disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acitretin Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acitretin Pancreatitis acute 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acitretin Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acitretin Psoriasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acitretin Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acitretin Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Acitretin Squamous cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acitretin Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acitretin Treatment failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aclidinium bromide Cardiac failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aclidinium bromide Diabetes mellitus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aclidinium bromide Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aclidinium bromide Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aclidinium bromide Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aclidinium bromide Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aclidinium bromide Urticaria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aclidinium bromide Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acyclovir Acute kidney injury 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Acyclovir Agitation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Agranulocytosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acyclovir Altered state of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Anaphylactic reaction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acyclovir Angioedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acyclovir Aplastic anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acyclovir Arthralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acyclovir Asthenia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Acyclovir Blister 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acyclovir Blood creatinine increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Body temperature increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acyclovir Bradyphrenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acyclovir Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Chills 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acyclovir Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acyclovir Decreased appetite 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Delirium 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Acyclovir Depressed level of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Dermatitis contact 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acyclovir Discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acyclovir Disseminated intravascular coagulation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Drug eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acyclovir Drug hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Drug resistance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acyclovir Eczema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acyclovir Encephalopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acyclovir Feeling abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acyclovir Gait disturbance 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Gastrointestinal disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Generalised oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Haematuria 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Acyclovir Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acyclovir Hepatitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Acyclovir Herpes simplex 1.0 1.0 0.0 0.0 1.0 0.0 0.0 Acyclovir Herpes zoster 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acyclovir Hyperbilirubinaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Hyperhidrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acyclovir Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Hypokalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acyclovir Jaundice 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Laboratory test abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acyclovir Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Liver function test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acyclovir Lymphadenopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Nasopharyngitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acyclovir Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acyclovir Nervous system disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acyclovir Oliguria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acyclovir Oropharyngeal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acyclovir Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Acyclovir Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acyclovir Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acyclovir Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Posterior reversible encephalopathy syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acyclovir Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Pyrexia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acyclovir Renal failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Renal impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Renal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acyclovir Renal tubular necrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acyclovir Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acyclovir Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Stevens-Johnson syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Stupor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Acyclovir Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Throat irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acyclovir Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Toxic epidermal necrolysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Acyclovir Tremor 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acyclovir Urinary retention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acyclovir Urine analysis abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acyclovir Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Acyclovir Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Adapalene Erythema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Adapalene Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Adapalene Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Adefovir dipivoxil Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Adefovir dipivoxil Blood alkaline phosphatase increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Adefovir dipivoxil Bone pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Adefovir dipivoxil Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Adefovir dipivoxil Drug resistance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Adefovir dipivoxil Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Adefovir dipivoxil Movement disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Adefovir dipivoxil Renal impairment 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Adenosine Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Adenosine Cardiac arrest 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Adenosine Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Adenosine Respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Adenosine Supraventricular tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Adenosine Ventricular fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Adenosine Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Afatinib Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Abdominal pain 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Afatinib Abdominal pain upper 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Afatinib Abscess 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Acne 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Acute hepatic failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Afatinib Acute myocardial infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Acute respiratory distress syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Alanine aminotransferase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Afatinib Alopecia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Altered state of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Afatinib Amnesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Amylase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Afatinib Anaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Afatinib Aphthous ulcer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Afatinib Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Aspartate aminotransferase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Afatinib Asthenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Atrial fibrillation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Back pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Bacterial infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Blood alkaline phosphatase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Blood bilirubin increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Blood count abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Blood creatinine increased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Afatinib Blood potassium decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Blood pressure decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Blood urine present 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Burning sensation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Candida infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Cardiac failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Afatinib Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Cerebral infarction 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Afatinib Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Cholangitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Chromaturia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Clostridium difficile colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Cognitive disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Confusional state 1.0 0.0 1.0 1.0 0.0 0.0 0.0 Afatinib Constipation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Cough 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Afatinib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Decreased appetite 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Deep vein thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Dehydration 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Afatinib Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Depressed level of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Dermatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Diarrhoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Diarrhoea haemorrhagic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Disorientation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Disseminated intravascular coagulation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Dizziness 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Drug eruption 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Afatinib Drug resistance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Afatinib Dry eye 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Afatinib Dry skin 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Dysgeusia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Dyspepsia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Dysphagia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Dysphonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Dyspnoea exertional 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Eating disorder 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Afatinib Eczema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Afatinib Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Afatinib Enterocolitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Epilepsy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Epistaxis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Erythema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Erythema multiforme 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Eye disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Fatigue 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Feeding disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Afatinib Flatulence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Folliculitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Fungal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Gastric haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Gastric ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Gastrointestinal haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Glossodynia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Haematochezia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Haematuria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Haemoptysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Hallucination 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Headache 1.0 0.0 1.0 1.0 0.0 0.0 0.0 Afatinib Hepatic enzyme increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Herpes zoster 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Hip fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Hyperglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Hyperkalaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Afatinib Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Afatinib Hyponatraemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Afatinib Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Hypotension 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Afatinib Hypoxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Inflammation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Afatinib Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Interstitial lung disease 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Afatinib Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Intestinal perforation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Jaundice 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Lip swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Liver disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Afatinib Liver function test increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Localised infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Afatinib Loss of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Lower respiratory tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Lung disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Afatinib Lung infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Lymphadenopathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Afatinib Malaise 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Afatinib Malnutrition 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Melaena 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Afatinib Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Metabolic acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Metastases to central nervous system 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Metastases to liver 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Metastases to lung 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Mouth ulceration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Mucosal inflammation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Muscle spasms 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Afatinib Muscular weakness 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Musculoskeletal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Myocardial infarction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Nail disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Nausea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Afatinib Neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Oesophagitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Oral pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Oropharyngeal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Oxygen saturation decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Afatinib Pancreatitis acute 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Afatinib Pancytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Peripheral swelling 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Platelet count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Pleural effusion 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Afatinib Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Pneumonia bacterial 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Pneumonitis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Afatinib Pneumothorax 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Afatinib Pruritus generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Pulmonary embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Afatinib Pyrexia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Afatinib Rash 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Rash erythematous 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Rash macular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Rash pruritic 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Afatinib Renal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Renal failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Renal impairment 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Afatinib Respiratory distress 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Afatinib Rhinorrhoea 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Afatinib Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Afatinib Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Afatinib Shock haemorrhagic 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Skin exfoliation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Afatinib Skin infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Skin reaction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Skin ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Somnolence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Staphylococcal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Stevens-Johnson syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Afatinib Stomatitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Thrombocytopenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Toxic epidermal necrolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Transaminases increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Transient ischaemic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Treatment failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Afatinib Unevaluable event 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Urosepsis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Vision blurred 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Afatinib Vomiting 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Weight decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Weight increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib Wheezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Afatinib White blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Albendazole Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Albendazole Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Albendazole Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Albiglutide Back pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Albiglutide Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Albiglutide Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Albiglutide Pneumonia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Albuterol Abdominal distension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Albuterol Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Albuterol Angioedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Albuterol Anxiety 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Albuterol Arthralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Albuterol Asthma 0.0 0.0 1.0 0.0 0.0 0.0 1.0 Albuterol Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Albuterol Body temperature increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Albuterol Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Albuterol Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Albuterol Cardiac disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Albuterol Chest discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Albuterol Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Albuterol Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Albuterol Decreased appetite 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Albuterol Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Albuterol Dysgeusia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Albuterol Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Albuterol Ear pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Albuterol Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Albuterol Fluid overload 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Albuterol Flushing 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Albuterol Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Albuterol Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Albuterol Hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Albuterol Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Albuterol Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Albuterol Lactic acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Albuterol Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Albuterol Mental disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Albuterol Metabolic acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Albuterol Migraine 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Albuterol Musculoskeletal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Albuterol Myalgia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Albuterol Mydriasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Albuterol Nasopharyngitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Albuterol Nervous system disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Albuterol Nervousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Albuterol Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Albuterol Otitis media 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Albuterol Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Albuterol Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Albuterol Pulmonary oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Albuterol Restlessness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Albuterol Retching 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Albuterol Supraventricular tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Albuterol Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Albuterol Throat irritation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Albuterol Tinnitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Albuterol Tremor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Albuterol Urinary tract disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Albuterol Urinary tract infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Albuterol Urticaria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Albuterol Wheezing 0.0 0.0 1.0 0.0 0.0 0.0 1.0 Albuterol sulfate Angioedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Albuterol sulfate Arrhythmia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Albuterol sulfate Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Albuterol sulfate Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Albuterol sulfate Bronchospasm 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Albuterol sulfate Chest discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Albuterol sulfate Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Albuterol sulfate Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Albuterol sulfate Flushing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Albuterol sulfate Hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Albuterol sulfate Irritability 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Albuterol sulfate Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Albuterol sulfate Nasal congestion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Albuterol sulfate Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Albuterol sulfate Wheezing 0.0 0.0 1.0 0.0 0.0 0.0 1.0 Alcohol Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alcohol Paraesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alectinib Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alectinib Blood creatine phosphokinase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alectinib Cardiac failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alectinib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alectinib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alectinib Haemolysis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alectinib Liver disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alectinib Metastases to central nervous system 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alectinib Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alectinib Oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alectinib Pneumonitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alectinib hydrochloride Back pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alectinib hydrochloride Blood creatinine increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alectinib hydrochloride Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alectinib hydrochloride Hyperbilirubinaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alectinib hydrochloride Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alectinib hydrochloride Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alectinib hydrochloride Vomiting 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alendronate sodium Abdominal distension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronate sodium Abdominal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronate sodium Alopecia 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Alendronate sodium Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronate sodium Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronate sodium Asthma 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronate sodium Bone pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronate sodium Constipation 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Alendronate sodium Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronate sodium Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronate sodium Dysgeusia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronate sodium Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronate sodium Dysphagia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronate sodium Erythema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronate sodium Femur fracture 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Alendronate sodium Flatulence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronate sodium Gastric ulcer 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronate sodium Gastritis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Alendronate sodium Gastrointestinal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronate sodium Gastrooesophageal reflux disease 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Alendronate sodium Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronate sodium Hypocalcaemia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronate sodium Joint swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronate sodium Malaise 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alendronate sodium Melaena 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alendronate sodium Mouth ulceration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alendronate sodium Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronate sodium Musculoskeletal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronate sodium Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronate sodium Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronate sodium Oesophageal ulcer 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alendronate sodium Oesophagitis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Alendronate sodium Osteonecrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronate sodium Osteonecrosis of jaw 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronate sodium Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronate sodium Pyrexia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronate sodium Rash 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronate sodium Urticaria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronate sodium Vertigo 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronate sodium Vomiting 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Abasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Abdominal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Abdominal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Abdominal pain upper 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Abscess 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alendronic acid Alanine aminotransferase increased 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Alendronic acid Alopecia 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Alendronic acid Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alendronic acid Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alendronic acid Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Arthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Arthropathy 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Aspartate aminotransferase increased 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Alendronic acid Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Asthma 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Atelectasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Atrial fibrillation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Bacterial infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alendronic acid Balance disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Basal cell carcinoma 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Alendronic acid Blister 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Blood cholesterol increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Bone disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Bone pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Bursitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid C-reactive protein increased 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Alendronic acid Cardiac failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alendronic acid Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Chest discomfort 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alendronic acid Chest pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Cholelithiasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Coma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alendronic acid Confusional state 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Conjunctivitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Contusion 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Deafness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alendronic acid Decreased appetite 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Dehydration 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alendronic acid Delirium 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alendronic acid Depressed mood 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Discomfort 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Drug eruption 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Alendronic acid Drug hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Drug interaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Drug intolerance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Dry eye 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Dysphagia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Dysphonia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Dyspnoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Dysuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Ear infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Emotional distress 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Erythema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Eye pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Feeding disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Feeling abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Feeling jittery 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Femur fracture 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Alendronic acid Flank pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Flatulence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Fracture 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Gastritis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alendronic acid Gastrointestinal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Gastrointestinal haemorrhage 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alendronic acid Gastrooesophageal reflux disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alendronic acid Glossodynia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Haematemesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alendronic acid Haematochezia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alendronic acid Haemoglobin decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alendronic acid Haemoptysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alendronic acid Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Hepatic enzyme increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Hepatic steatosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Hypercalcaemia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Alendronic acid Hypersensitivity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Hypertension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Hypoacusis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Hypoaesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Hypocalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alendronic acid Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alendronic acid Hypophosphataemia 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Alendronic acid Ill-defined disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Infection 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Alendronic acid Inflammation 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Alendronic acid Influenza 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Influenza like illness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Interstitial lung disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Irritable bowel syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Joint stiffness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Joint swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Limb discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Lower respiratory tract infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Lung disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alendronic acid Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Melaena 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alendronic acid Mobility decreased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Mouth ulceration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alendronic acid Muscle spasms 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Musculoskeletal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Musculoskeletal stiffness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Myelodysplastic syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alendronic acid Myocardial infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alendronic acid Nail disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Nasopharyngitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Nodule 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Obstructive airways disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alendronic acid Ocular hyperaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Oesophageal ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alendronic acid Oesophagitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alendronic acid Oral pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Oropharyngeal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alendronic acid Osteonecrosis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Alendronic acid Osteonecrosis of jaw 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Alendronic acid Oxygen saturation decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Pain in jaw 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alendronic acid Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alendronic acid Pericarditis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Plasma cell myeloma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alendronic acid Pneumonia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Pneumonia aspiration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alendronic acid Productive cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alendronic acid Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Pulmonary embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alendronic acid Pyrexia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Rash 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Rash erythematous 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Red blood cell count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Red blood cell sedimentation rate increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Respiratory tract congestion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Rheumatoid arthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Rhinorrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Sciatica 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Sinusitis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Skin ulcer 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Alendronic acid Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alendronic acid Spinal fracture 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Stomatitis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Swelling 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Swelling face 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Syncope 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Systemic lupus erythematosus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Tenderness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Tendonitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Treatment failure 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Ulcer 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Upper gastrointestinal haemorrhage 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alendronic acid Urinary tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Urticaria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Vertigo 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alendronic acid Visual acuity reduced 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Alendronic acid Vomiting 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alendronic acid Wheezing 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alfuzosin Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alfuzosin Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alfuzosin Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alfuzosin Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alfuzosin Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alfuzosin Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alfuzosin Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alfuzosin hydrochloride Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aliskiren Abdominal distension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Aliskiren Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aliskiren Acute myocardial infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aliskiren Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aliskiren Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Aliskiren Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aliskiren Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aliskiren Blood pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aliskiren Cardiac failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Aliskiren Cardiac failure congestive 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Aliskiren Cardiomegaly 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aliskiren Cerebrovascular accident 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aliskiren Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aliskiren Chronic kidney disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aliskiren Coronary artery disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aliskiren Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aliskiren Death 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Aliskiren Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aliskiren Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aliskiren Disease progression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aliskiren Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aliskiren Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aliskiren Hepatic function abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aliskiren Hyperkalaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Aliskiren Hypotension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Aliskiren Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aliskiren Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aliskiren Metabolic acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aliskiren Muscular weakness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aliskiren Myocardial ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aliskiren Nausea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aliskiren Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aliskiren Pain in extremity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aliskiren Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Aliskiren Pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aliskiren Pyrexia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Aliskiren Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Aliskiren Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aliskiren Septic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aliskiren Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aliskiren Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aliskiren Ventricular tachycardia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Aliskiren Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Aliskiren hemifumarate Gastrooesophageal reflux disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aliskiren hemifumarate Oedema peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Allopurinol Abdominal distension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Abdominal pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Acute hepatic failure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Acute kidney injury 1.0 1.0 1.0 0.0 0.0 1.0 0.0 Allopurinol Acute respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Agitation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Agranulocytosis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Alanine aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Alopecia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Allopurinol Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Anaphylactic shock 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Angina pectoris 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Allopurinol Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Angiopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Anuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Aplastic anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Arthralgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Allopurinol Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Asthenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Atrial fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Atrioventricular block complete 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Balance disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Blister 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Allopurinol Blood creatine phosphokinase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Blood urea increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Bone marrow failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Bronchospasm 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol C-reactive protein increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Candida infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Cardiac disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Cardiac failure 1.0 1.0 0.0 0.0 1.0 0.0 0.0 Allopurinol Cardiac failure acute 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Cardiac failure congestive 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Cardiogenic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Cardiomegaly 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Cerebral infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Cheilitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Chest pain 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Allopurinol Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Cholecystitis acute 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Cholelithiasis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Chromaturia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Chronic kidney disease 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Circulatory collapse 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Coagulopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Cognitive disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Coma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Confusional state 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Conjunctival hyperaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Conjunctivitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Constipation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Contusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Cough 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Decreased appetite 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Depressed level of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Allopurinol Dermatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Dermatitis bullous 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Dermatitis exfoliative 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Diarrhoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Diarrhoea haemorrhagic 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Disseminated intravascular coagulation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Drug eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Drug hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Allopurinol Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Drug-induced liver injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Dysarthria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Dysgeusia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Dysphagia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Dyspnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Eczema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Encephalitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Encephalopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Eosinophilia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Epistaxis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Allopurinol Erythema 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Erythema multiforme 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Face oedema 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Febrile neutropenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Gastric ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Gastritis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Haematoma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Haemolytic anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Haemorrhage intracranial 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Haemorrhagic stroke 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Hallucination 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Hallucination, visual 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Hepatic enzyme abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Hepatic enzyme increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Hepatic function abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Hepatitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Hepatitis acute 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Hepatitis cholestatic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Hepatocellular injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Hepatomegaly 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Herpes simplex 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Hyperbilirubinaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Hyperglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Hyperhidrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Hyperkalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Hyperpyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Hypersensitivity vasculitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Hyperthermia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Hyperuricaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Hypoaesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Allopurinol Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Hyponatraemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Hypotension 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Hypothyroidism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Hypovolaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Hypoxia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Ileus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Interstitial lung disease 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Ischaemic stroke 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Lactic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Leukocytosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Lipase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Liver disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Liver function test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Liver injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Lung disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Lymphadenopathy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Lymphopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Malaise 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Allopurinol Melaena 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Metabolic acidosis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Metabolic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Mouth ulceration 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Mucosal inflammation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Muscular weakness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Allopurinol Myalgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Allopurinol Myocarditis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Myopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Nausea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Neck pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Necrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Nervous system disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Ocular hyperaemia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Allopurinol Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Oedema peripheral 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Allopurinol Oliguria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Oral disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Oropharyngeal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Oropharyngeal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Orthostatic hypotension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Allopurinol Pain in extremity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Pancreatitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Pancytopenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Pericarditis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Petechiae 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Photosensitivity reaction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Pleural effusion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Pleurisy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Pneumonia aspiration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Pneumonitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Polyneuropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Allopurinol Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Allopurinol Pruritus 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Pruritus generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Pulmonary fibrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Pyelonephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Rash 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Allopurinol Rash erythematous 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Rash generalised 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Allopurinol Rash macular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Rash papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Rash pruritic 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Allopurinol Rash pustular 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Rash vesicular 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Renal impairment 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Renal tubular necrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Respiratory distress 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Rhabdomyolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Rhinorrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Scab 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Skin disorder 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Allopurinol Skin exfoliation 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Allopurinol Skin lesion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Skin ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Somnolence 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Allopurinol Staphylococcal infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Stevens-Johnson syndrome 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Stomatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Stress cardiomyopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Subarachnoid haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Swelling face 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Tachypnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Thrombocytopenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Toxic epidermal necrolysis 1.0 1.0 0.0 0.0 1.0 0.0 0.0 Allopurinol Toxic skin eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Transaminases increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Tubulointerstitial nephritis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Tumour lysis syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Urinary retention 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Vascular purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Visual impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Weight increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Allopurinol Wheezing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Allopurinol White blood cell count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Almotriptan Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alogliptin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alogliptin Diabetes mellitus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alogliptin Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alogliptin Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alogliptin Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alogliptin Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alogliptin Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alogliptin benzoate Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alpelisib Abdominal distension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alpelisib Abdominal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alpelisib Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alpelisib Anaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Alpelisib Anaphylactic reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alpelisib Blood creatinine increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alpelisib Blood glucose increased 0.0 0.0 1.0 0.0 0.0 1.0 0.0 Alpelisib Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alpelisib Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alpelisib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alpelisib Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alpelisib Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alpelisib Diabetic ketoacidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alpelisib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alpelisib Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Alpelisib Feeling abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alpelisib Hyperglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alpelisib Hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alpelisib Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alpelisib Lip swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alpelisib Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alpelisib Metastases to central nervous system 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alpelisib Metastases to liver 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alpelisib Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alpelisib Pleural effusion 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Alpelisib Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Alpelisib Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alpelisib Rash macular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alpelisib Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alpelisib Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alpelisib Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alpelisib Sepsis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Alpelisib Skin exfoliation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alpelisib Skin ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alpelisib Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alpelisib Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Abasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Abdominal pain upper 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Acute coronary syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Acute hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Acute kidney injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Acute respiratory failure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Agitation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Akathisia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Altered state of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Amnesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Anal incontinence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Anger 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Angina pectoris 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alprazolam Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Aphasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Apnoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Asphyxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Ataxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Atrial septal defect 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Alprazolam Atrioventricular block 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Balance disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Blood cholesterol increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Blood creatine phosphokinase increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Blood creatinine increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Blood pressure increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Bone marrow failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Bradyphrenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Brain injury 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Brain oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alprazolam Burning sensation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alprazolam C-reactive protein increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Cardiac disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Cardiac tamponade 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Cardiogenic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Catatonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Cholestasis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Cognitive disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Coma 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Confusional state 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Crying 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Cyanosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alprazolam Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Decreased appetite 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Alprazolam Decubitus ulcer 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Delirium 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Delusion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Depersonalisation/derealisation disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Depressed level of consciousness 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alprazolam Disorientation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Disturbance in attention 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Alprazolam Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Drug withdrawal syndrome 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Alprazolam Dysarthria 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Dyskinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Dysphagia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Dyspnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Ejection fraction decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Electrocardiogram QT prolonged 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Emotional distress 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Encephalopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Eosinophilia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Epilepsy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Erythema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Extrapyramidal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Eye disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alprazolam Face oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Fear 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Feeling abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Feeling jittery 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alprazolam Foetal death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Gait disturbance 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Alprazolam Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Gastrointestinal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Generalised tonic-clonic seizure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alprazolam Haemodynamic instability 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Haemoglobin decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Hallucination 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Hallucination, auditory 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Hallucination, visual 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Heart rate increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Hepatic failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Hepatic function abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Hepatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Hepatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Hepatitis cholestatic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Hepatocellular injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Hepatotoxicity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Hyperkalaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Hypersensitivity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Hypersomnia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Hypertension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Hypoaesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Hypoglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Hypokinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Hyponatraemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Hyporeflexia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Hypothermia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Hypotonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Hypoxia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Infection 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Insomnia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Intentional self-injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Interstitial lung disease 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Irritability 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Lacrimation increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alprazolam Lactic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Leukocytosis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Leukopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Lipase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Loss of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Lung disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Lung infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Mania 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Mental disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Mental impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Metabolic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Miosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Mitral valve incompetence 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Mobility decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alprazolam Motor dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alprazolam Mucosal inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Muscle rigidity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Muscle spasms 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Muscle twitching 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Musculoskeletal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Mydriasis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Myocardial ischaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Myoclonus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Nervous system disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Nightmare 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alprazolam Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Oxygen saturation decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Palpitations 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Pancreatitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Pancytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Panic attack 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Paraesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Paranoia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Peripheral swelling 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Photophobia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Pleural effusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Pneumonia aspiration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Pneumonitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Premature baby 0.0 0.0 1.0 0.0 1.0 0.0 0.0 Alprazolam Psychomotor hyperactivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Psychotic disorder 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Alprazolam Pulmonary congestion 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Pulmonary embolism 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Rales 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Renal failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Renal impairment 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Respiratory depression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Respiratory disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Respiratory distress 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Restlessness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Salivary hypersecretion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alprazolam Sedation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Septic shock 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Serotonin syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Sinus bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Sinus tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Skin disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Sleep disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Sluggishness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Somnolence 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Sopor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Status epilepticus 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Stress 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Suicidal ideation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Suicide attempt 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Thinking abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Throat tightness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alprazolam Tinnitus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Torsade de pointes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Toxic epidermal necrolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Transaminases increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Tremor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Unevaluable event 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Unresponsive to stimuli 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alprazolam Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Vision blurred 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Visual impairment 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Alprazolam Weight decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Alprazolam Withdrawal syndrome 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Alprostadil Angiopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alprostadil Apnoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alprostadil Blood alkaline phosphatase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alprostadil Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alprostadil Cerebrovascular accident 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alprostadil Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alprostadil Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alprostadil Haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Alprostadil Hypokalaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alprostadil Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Alteplase Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Alteplase Haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Alteplase Haemorrhage intracranial 1.0 1.0 0.0 0.0 0.0 1.0 0.0 Alteplase Pulmonary embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Alteplase Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amantadine Acute kidney injury 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine Aggression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine Amnesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine Ataxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amantadine Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amantadine Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine Dehydration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine Delusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine Disorientation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amantadine Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine Dry mouth 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amantadine Dyskinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine Dysphagia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine Hallucination, visual 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine Insomnia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amantadine Leukocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine Neuroleptic malignant syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine Orthostatic hypotension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amantadine Seizure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine Unevaluable event 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine Urinary retention 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine Visual impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine Vomiting 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amantadine hydrochloride Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine hydrochloride Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine hydrochloride Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine hydrochloride Delusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine hydrochloride Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amantadine hydrochloride Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amantadine hydrochloride Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine hydrochloride Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine hydrochloride Neuroleptic malignant syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amantadine hydrochloride Psychotic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine hydrochloride Somnolence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amantadine hydrochloride Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amantadine hydrochloride Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Abasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Abdominal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Abscess 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Acute kidney injury 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Acute myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ambrisentan Acute respiratory distress syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ambrisentan Acute respiratory failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Appendicitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Arrhythmia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Asthma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Atrial flutter 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Bacteraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Bacterial infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Balance disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Basal cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ambrisentan Blindness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ambrisentan Blood bilirubin increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ambrisentan Blood count abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Blood creatinine increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Blood disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Blood glucose decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Blood magnesium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Blood potassium increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Blood pressure abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Blood pressure decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Blood urine present 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Bradycardia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Brain injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ambrisentan Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ambrisentan Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ambrisentan Cardiac disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Cardiac failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Cardiac failure acute 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ambrisentan Cardiogenic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ambrisentan Cardiopulmonary failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ambrisentan Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ambrisentan Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Cerebral haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Cerebrovascular accident 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Cholecystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Cholecystitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Chronic kidney disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ambrisentan Chronic obstructive pulmonary disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Circulatory collapse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ambrisentan Clostridium difficile infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Coma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Contusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Coronary artery disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ambrisentan Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Cyst 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Cystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ambrisentan Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ambrisentan Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Deep vein thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Dementia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ambrisentan Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ambrisentan Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ambrisentan Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Drug hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Drug intolerance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Dyspepsia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Dyspnoea exertional 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Ear infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Epistaxis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Erythema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Eye disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ambrisentan Eye haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ambrisentan Eye swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Facial paralysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Faeces discoloured 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Feeding disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Feeling abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Flank pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Fluid overload 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Fluid retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Flushing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Gallbladder disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Gastric disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Gastric haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Gastroenteritis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Gastroenteritis viral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Gastrooesophageal reflux disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Generalised oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ambrisentan Glossodynia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Gout 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Haematemesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Haematochezia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Haemodynamic instability 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ambrisentan Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Haemoptysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Haemorrhage intracranial 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ambrisentan Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Heart rate decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Heart rate irregular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Hepatic cirrhosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ambrisentan Hepatic encephalopathy 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ambrisentan Hepatic function abnormal 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ambrisentan Hernia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Herpes zoster 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Hip fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Hyperglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Hyperkalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Hypoaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Hypovolaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Hypoxia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Ill-defined disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Influenza like illness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Interstitial lung disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ambrisentan Intervertebral disc protrusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Iron deficiency anaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Joint swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Laboratory test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Laceration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Leukocytosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ambrisentan Liver disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Localised infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 1.0 Ambrisentan Lower respiratory tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ambrisentan Lung disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Lung infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ambrisentan Lymphoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ambrisentan Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Memory impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Mental disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Migraine 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Mobility decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ambrisentan Muscle spasms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Musculoskeletal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Myocardial infarction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Neck pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ambrisentan Nervous system disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Oesophagitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Oropharyngeal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Osteoporosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ambrisentan Otitis media 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ambrisentan Oxygen saturation decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Pain in jaw 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Pancreatic carcinoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ambrisentan Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Panic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Pericardial effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Peritonitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ambrisentan Pharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Platelet count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Pleurisy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ambrisentan Pneumonia bacterial 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Pneumothorax 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Polyuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Productive cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Pulmonary embolism 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Pulmonary fibrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ambrisentan Pulmonary hypertension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Pulmonary mass 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Red blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Renal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Renal failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Renal impairment 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ambrisentan Respiratory disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Respiratory distress 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Respiratory failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Respiratory tract congestion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Retinal detachment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ambrisentan Rheumatoid arthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ambrisentan Rhinitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Rhinorrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Sepsis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ambrisentan Shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ambrisentan Sinusitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Skin infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Skin ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Small intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Speech disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Staphylococcal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Subdural haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ambrisentan Supraventricular tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Swelling face 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Syncope 0.0 0.0 1.0 0.0 0.0 0.0 1.0 Ambrisentan Systemic lupus erythematosus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ambrisentan Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Tachypnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Thrombocytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ambrisentan Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Transient ischaemic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Unevaluable event 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Unresponsive to stimuli 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Upper gastrointestinal haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Upper limb fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Upper respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Urticaria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Ventricular tachycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ambrisentan Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Vision blurred 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Weight increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan Wheezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan White blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ambrisentan White blood cell count increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Anxiety 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amikacin Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Asthenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amikacin Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Cough 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amikacin Decreased appetite 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Drug hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Drug intolerance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Dysgeusia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Dysphonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Fatigue 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Haemoptysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Lung disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Malaise 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Nausea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Productive cough 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Respiratory disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Respiratory failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Sepsis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Throat irritation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amikacin Weight decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiloride hydrochloride Hyperkalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aminophylline Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Abasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Abdominal distension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Abdominal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Abdominal pain upper 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Acute coronary syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Acute hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Acute respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Agitation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Altered state of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Amnesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Anaemia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Amiodarone Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Angina pectoris 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Apnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Arrhythmia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Arthralgia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Amiodarone Asthenia 1.0 1.0 0.0 1.0 0.0 1.0 0.0 Amiodarone Ataxia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amiodarone Atrial fibrillation 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Amiodarone Atrial flutter 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Atrioventricular block 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Atrioventricular block complete 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Atrioventricular block first degree 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Atrioventricular block second degree 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Back pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Balance disorder 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Amiodarone Blindness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Cardiac failure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Cardiac failure acute 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Cardiac failure congestive 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Cardiogenic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Cataract 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Chest pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Chronic kidney disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Chronic obstructive pulmonary disease 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Coagulopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Cognitive disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Confusional state 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Congestive cardiomyopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Coordination abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Cough 1.0 1.0 0.0 1.0 0.0 1.0 0.0 Amiodarone Cyanosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Death 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Decreased appetite 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Dehydration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Depression 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Diplopia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Disturbance in attention 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Drug interaction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Drug-induced liver injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Dyspepsia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Dyspnoea 1.0 1.0 1.0 1.0 0.0 1.0 0.0 Amiodarone Dyspnoea exertional 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Ejection fraction decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Amiodarone Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Erythema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Extrapyramidal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Eye irritation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Eye pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Fatigue 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Fungal skin infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Gait disturbance 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Gastrointestinal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Haemodynamic instability 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Haemoptysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Haemorrhage 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Hallucination, visual 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Heart rate increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Heart rate irregular 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Hepatic cirrhosis 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Hepatic encephalopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Hepatic enzyme increased 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Amiodarone Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Hepatic function abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Hepatic steatosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Hepatitis acute 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Hepatotoxicity 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Hyperkalaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Hyperthyroidism 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Amiodarone Hypoaesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Hypoglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Hypokinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Hypotension 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Hypothermia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Hypothyroidism 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Amiodarone Hypoxia 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Insomnia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Interstitial lung disease 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Irritability 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Jaundice 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Lethargy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Leukocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Liver disorder 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Amiodarone Liver function test abnormal 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Liver function test increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Liver injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Loss of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Lung disorder 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Lung infiltration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Malaise 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Melaena 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Metabolic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Mitral valve incompetence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Nausea 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Nephropathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Nervous system disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Nervousness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Nightmare 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amiodarone Oedema 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Optic neuritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Oxygen saturation decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Palpitations 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Pancytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Parkinsonism 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Pericardial effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Pigmentation disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Pleural effusion 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Amiodarone Pneumonia 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Pneumonitis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Productive cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Pulmonary alveolar haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Pulmonary embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Pulmonary fibrosis 1.0 1.0 0.0 1.0 0.0 1.0 0.0 Amiodarone Pulmonary haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Pulmonary hypertension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Pulmonary mass 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Pulmonary oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Rales 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Rectal haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Renal disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Renal impairment 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Respiratory distress 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Respiratory failure 1.0 1.0 0.0 0.0 0.0 1.0 0.0 Amiodarone Restlessness 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Rhabdomyolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Sinus bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Skin discolouration 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Sleep disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amiodarone Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Swelling 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Syncope 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Tachypnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Torsade de pointes 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Toxic epidermal necrolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Toxic skin eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Transaminases increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Transient ischaemic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Treatment failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Tremor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Urinary tract infection 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Ventricular arrhythmia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Ventricular extrasystoles 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Ventricular fibrillation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Vision blurred 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Visual acuity reduced 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Visual field defect 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Visual impairment 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amiodarone Weight decreased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone Wheezing 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone hydrochloride Abdominal pain 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Alopecia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone hydrochloride Arrhythmia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Asthenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Atrioventricular block 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Cardiac failure congestive 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Coagulopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Confusional state 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Coordination abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone hydrochloride Cough 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amiodarone hydrochloride Delirium 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Disturbance in attention 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone hydrochloride Dyspnoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Fatigue 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Flushing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Gait disturbance 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Haemoptysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Hallucination 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone hydrochloride Hepatic enzyme increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Hepatic function abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Hepatitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Hepatitis cholestatic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Hyperthyroidism 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Hypotension 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Hypothyroidism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Hypoxia 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone hydrochloride Insomnia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone hydrochloride Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Liver disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Liver injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Lung infiltration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Malaise 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amiodarone hydrochloride Oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Palpitations 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Pancytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amiodarone hydrochloride Parkinsonism 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amiodarone hydrochloride Photosensitivity reaction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Pulmonary alveolar haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Pulmonary fibrosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Pyrexia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Renal impairment 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Respiratory disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Respiratory distress 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Restlessness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Syncope 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Thrombocytopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Tremor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone hydrochloride Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Vision blurred 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone hydrochloride Visual impairment 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amiodarone hydrochloride Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amiodarone hydrochloride Wheezing 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amitriptyline Agitation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Arrhythmia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amitriptyline Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Balance disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amitriptyline Circulatory collapse 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amitriptyline Coma 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amitriptyline Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amitriptyline Confusional state 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Constipation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Coordination abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amitriptyline Decreased appetite 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Delusion 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Disorientation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Drug withdrawal syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amitriptyline Dyskinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Dyspepsia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amitriptyline Dyspnoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amitriptyline Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amitriptyline Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amitriptyline Hallucination 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amitriptyline Hypoaesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amitriptyline Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Irritability 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amitriptyline Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amitriptyline Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Mania 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Mental status changes 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amitriptyline Mydriasis 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Amitriptyline Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Neuroleptic malignant syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Nightmare 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amitriptyline Palpitations 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Paraesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Pollakiuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Pruritus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amitriptyline Seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amitriptyline Serotonin syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amitriptyline Sleep disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Somnolence 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Suicide attempt 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amitriptyline Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amitriptyline Tachycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amitriptyline Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Torsade de pointes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amitriptyline Tremor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Urinary retention 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amitriptyline Ventricular fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amitriptyline Ventricular tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amitriptyline Vision blurred 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amitriptyline Vomiting 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Amitriptyline hydrochloride Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amitriptyline hydrochloride Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amitriptyline hydrochloride Hypotension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amitriptyline hydrochloride Serotonin syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amitriptyline hydrochloride Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amlodipine besylate Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amlodipine besylate Affect lability 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Agitation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amlodipine besylate Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Amnesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Angina pectoris 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amlodipine besylate Angioedema 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Amlodipine besylate Angiopathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Apathy 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Arrhythmia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amlodipine besylate Arthralgia 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Amlodipine besylate Arthropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amlodipine besylate Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Atrial fibrillation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amlodipine besylate Back pain 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Amlodipine besylate Bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amlodipine besylate Cardiac disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Cardiac failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Amlodipine besylate Chest pain 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Amlodipine besylate Chills 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Cholestasis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Amlodipine besylate Cold sweat 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amlodipine besylate Decreased appetite 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Diplopia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Discomfort 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Amlodipine besylate Dizziness 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Amlodipine besylate Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Amlodipine besylate Dry skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amlodipine besylate Dysgeusia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Dysphagia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Dyspnoea 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Amlodipine besylate Dysuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Epistaxis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amlodipine besylate Erectile dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Amlodipine besylate Extrasystoles 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Eye pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Amlodipine besylate Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Feeling abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Flushing 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Gastrointestinal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Gynaecomastia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Headache 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Amlodipine besylate Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amlodipine besylate Hepatitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amlodipine besylate Hot flush 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Amlodipine besylate Hyperglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amlodipine besylate Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Hypersensitivity 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amlodipine besylate Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Amlodipine besylate Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amlodipine besylate Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Jaundice 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Amlodipine besylate Leukopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amlodipine besylate Loss of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amlodipine besylate Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Malnutrition 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amlodipine besylate Mental disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Micturition disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amlodipine besylate Migraine 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Amlodipine besylate Mood swings 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Amlodipine besylate Muscle twitching 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amlodipine besylate Muscular weakness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Amlodipine besylate Myocardial infarction 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Nausea 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Amlodipine besylate Nervous system disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amlodipine besylate Nervousness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Neuropathy peripheral 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amlodipine besylate Nocturia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amlodipine besylate Oedema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Oedema peripheral 0.0 0.0 1.0 0.0 0.0 1.0 0.0 Amlodipine besylate Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amlodipine besylate Osteoarthritis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amlodipine besylate Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Palpitations 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Pancreatitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amlodipine besylate Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Peripheral ischaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amlodipine besylate Pollakiuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Amlodipine besylate Rash 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Rash erythematous 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amlodipine besylate Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amlodipine besylate Rhinitis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Shock 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amlodipine besylate Skin discolouration 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Somnolence 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amlodipine besylate Syncope 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amlodipine besylate Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amlodipine besylate Thirst 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amlodipine besylate Thrombocytopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amlodipine besylate Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amlodipine besylate Vasculitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amlodipine besylate Vertigo 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Amlodipine besylate Visual impairment 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Amlodipine besylate Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amlodipine besylate Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amlodipine besylate Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Abdominal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Abdominal distension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Abdominal pain upper 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Acute generalised exanthematous pustulosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Acute hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Acute respiratory distress syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Agranulocytosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Alanine aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Anal incontinence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Amoxicillin Anaphylactic shock 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Anaphylactoid reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Anuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Aphthous ulcer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Arthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Aspartate aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Blister 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Blood alkaline phosphatase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Blood bilirubin increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Blood creatine phosphokinase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Blood creatinine increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Blood pressure decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Bone marrow failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Bone pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Bronchitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Burning sensation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin C-reactive protein increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Candida infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Cardiopulmonary failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Cardiovascular disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Chest discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Chills 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Choking 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Cholecystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Circulatory collapse 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Clostridium difficile colitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Clostridium difficile infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Coagulopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Confusional state 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Conjunctival hyperaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Conjunctivitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Contusion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Crohn's disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Cyanosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Deafness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Delirium 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Depressed mood 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Dermatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Dermatitis allergic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Dermatitis bullous 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Diplopia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Drug abuse 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Drug eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Drug hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Drug intolerance 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Drug resistance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Drug-induced liver injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Dry skin 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Dysarthria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Dysgeusia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Dysphagia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Dysphonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Ecchymosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Eczema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Encephalitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Enteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Enterocolitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Eosinophilia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Eye pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Eye swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Eyelid oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Face oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Feeling abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Feeling hot 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Flank pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Flatulence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Flushing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Foetal growth restriction 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Amoxicillin Gait disturbance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Gamma-glutamyltransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Gastrooesophageal reflux disease 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Generalised oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Haemodynamic instability 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Haemolytic anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Haemorrhoids 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Hallucination 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Heart rate increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Hepatic failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Hepatic function abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Hepatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Hepatitis acute 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Hepatitis cholestatic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Hepatocellular injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Hydronephrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Hyperbilirubinaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Hyperkalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Hypersensitivity vasculitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Hypertension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Hyperthermia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Hypoaesthesia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Amoxicillin Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Hypoxia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Infection 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Influenza 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Amoxicillin Irritability 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Irritable bowel syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Jaundice cholestatic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Joint swelling 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Laryngeal oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Leukocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Leukopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Lip swelling 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Liver disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Liver function test abnormal 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Liver injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Lower respiratory tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Lung infiltration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Lymphadenopathy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Malaise 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Metabolic acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Muscle spasms 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Muscle twitching 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Muscular weakness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Musculoskeletal stiffness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Myoclonus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Nausea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Nephropathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Nervous system disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Nervousness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Obstructive airways disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Ocular hyperaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Oedema peripheral 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Oral discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Oral pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Oropharyngeal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Oxygen saturation decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Pallor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Palpitations 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Pancytopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Panic attack 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Paraesthesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Parosmia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Petechiae 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Pharyngeal oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Pharyngitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Photophobia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Photosensitivity reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Platelet count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Pneumonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Pneumonia bacterial 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Pneumonitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Pneumothorax 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Pollakiuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Amoxicillin Premature delivery 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Presyncope 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Proteinuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Pruritus 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Amoxicillin Pruritus generalised 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Pseudomembranous colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Psychotic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Pulmonary alveolar haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Pulmonary oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Rash 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Amoxicillin Rash erythematous 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Rash generalised 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Rash macular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Rash vesicular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Renal failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Renal impairment 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Renal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Renal tubular necrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Respiratory distress 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Restlessness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Rhinorrhoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Sinusitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Skin burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Skin exfoliation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Skin lesion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Skin reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Sleep disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Sopor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Speech disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Splenomegaly 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Stevens-Johnson syndrome 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Stomatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Stress 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Swelling face 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Swollen tongue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Throat irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Throat tightness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amoxicillin Thrombocytopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Tongue oedema 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Toxic epidermal necrolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Toxic skin eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Transaminases increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Treatment failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Tremor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Tubulointerstitial nephritis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Urinary incontinence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Urinary tract infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Urticaria 0.0 1.0 0.0 0.0 0.0 1.0 1.0 Amoxicillin Vascular purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Vasculitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amoxicillin Vertigo 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Visual impairment 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Amoxicillin Weight decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin Wheezing 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Amoxicillin White blood cell count increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amphetamine Cardiomyopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amphetamine Cerebrovascular accident 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amphetamine Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amphetamine Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amphetamine Metabolic acidosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amphetamine Rhabdomyolysis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Amphetamine Seizure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amphetamine sulfate Rhabdomyolysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Abdominal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Acute kidney injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Acute myeloid leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Alanine aminotransferase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Anaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Aspartate aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Back pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Blood alkaline phosphatase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amphotericin b Blood creatinine increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Blood potassium decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Bone marrow failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Candida infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Chills 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Confusional state 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Depressed level of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Dermatitis exfoliative 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amphotericin b Diarrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Amphotericin b Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amphotericin b Febrile neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Fungal infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Gastrointestinal disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Haemoptysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Hepatic enzyme increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Hepatic function abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Hyperkalaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Hypokalaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Hypoxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Jaundice 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Liver function test abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amphotericin b Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Oxygen saturation decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amphotericin b Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Platelet count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Pruritus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Pyrexia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Rash 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Renal disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Renal impairment 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Respiratory disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Respiratory distress 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Stevens-Johnson syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Tachypnoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Amphotericin b Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Toxic epidermal necrolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Amphotericin b Vomiting 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ampicillin Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ampicillin Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ampicillin Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ampicillin Urticaria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Anagrelide Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Anagrelide Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anagrelide hydrochloride Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Anagrelide hydrochloride Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Anagrelide hydrochloride Dyspnoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Anagrelide hydrochloride Headache 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Anagrelide hydrochloride Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Anagrelide hydrochloride Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Anastrozole Abasia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Abdominal pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Anastrozole Acute hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Anastrozole Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Anastrozole Acute myeloid leukaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Anastrozole Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Anastrozole Amnesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Anastrozole Anger 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Anastrozole Arthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Anastrozole Arthropathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Anastrozole Ascites 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Anastrozole Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Anastrozole Atrial fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Anastrozole Back pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Anastrozole Balance disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Anastrozole Blister 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Anastrozole Blood alkaline phosphatase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Blood creatinine increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Anastrozole Blood pressure decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Anastrozole Bone disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Anastrozole Bone pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Anastrozole Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Breast pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Burning sensation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Anastrozole Cardiac arrest 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Anastrozole Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Anastrozole Cardiomyopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Anastrozole Carpal tunnel syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Anastrozole Cataract 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Anastrozole Cellulitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Anastrozole Cerebral infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Anastrozole Cerebrovascular accident 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Anastrozole Cognitive disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Contusion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Cystitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Anastrozole Death 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Anastrozole Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Anastrozole Deep vein thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Anastrozole Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Anastrozole Depression 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Anastrozole Dermatitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Anastrozole Dermatitis bullous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Diarrhoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Anastrozole Discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Disease recurrence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Drug abuse 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Anastrozole Drug hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Anastrozole Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Drug reaction with eosinophilia and systemic symptoms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Anastrozole Drug resistance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Dry eye 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Anastrozole Dry skin 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Anastrozole Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Dysphagia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Anastrozole Dysphonia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Dysstasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Anastrozole Emotional distress 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Epistaxis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Anastrozole Fear 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Anastrozole Feeling hot 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Anastrozole Femur fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Anastrozole Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Anastrozole Gamma-glutamyltransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Anastrozole Gastrooesophageal reflux disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Haematochezia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Anastrozole Haemorrhage 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Anastrozole Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Hepatic cirrhosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Anastrozole Hepatic enzyme increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Anastrozole Hepatic function abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Anastrozole Hepatic steatosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Hepatotoxicity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Anastrozole Hot flush 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Hypercalcaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Anastrozole Hypercholesterolaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Hyperhidrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Anastrozole Hypoacusis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Anastrozole Infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Inflammation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Anastrozole Interstitial lung disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Anastrozole Ischaemic stroke 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Anastrozole Joint stiffness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Anastrozole Joint swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Anastrozole Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Limb discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Lip swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Liver disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Anastrozole Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Anastrozole Lung neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Malignant neoplasm progression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Memory impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Menopausal symptoms 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Anastrozole Metastases to liver 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Metastases to lung 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Metastatic neoplasm 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Mitral valve incompetence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Anastrozole Mobility decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Anastrozole Mood swings 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Anastrozole Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Anastrozole Musculoskeletal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Musculoskeletal stiffness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Anastrozole Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Anastrozole Myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Anastrozole Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Neoplasm progression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Neuralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Anastrozole Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Anastrozole Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Neutrophil count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Oedema peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Osteoarthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Anastrozole Osteonecrosis of jaw 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Osteoporosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Anastrozole Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Anastrozole Pain in jaw 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Pancytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Anastrozole Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Anastrozole Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Anastrozole Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Anastrozole Pneumonitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Anastrozole Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Anastrozole Pulmonary embolism 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Anastrozole Pulmonary hypertension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Anastrozole Pyrexia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Anastrozole Rash 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Rash erythematous 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Anastrozole Respiratory failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Anastrozole Retinal detachment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Anastrozole Rheumatoid arthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Sciatica 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Skin exfoliation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Anastrozole Skin mass 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Sleep disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Subarachnoid haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Anastrozole Suicidal ideation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Tendonitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Anastrozole Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Anastrozole Thrombophlebitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anastrozole Thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Anastrozole Thrombotic thrombocytopenic purpura 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Anastrozole Transient ischaemic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Anastrozole Urinary incontinence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Anastrozole Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Anastrozole Vaginal discharge 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Anastrozole Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Anastrozole Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Anastrozole Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Anastrozole Weight increased 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Anastrozole White blood cell count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Anidulafungin Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apalutamide Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apalutamide Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apalutamide Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apalutamide Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apalutamide Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apalutamide Cerebral infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apalutamide Cerebrovascular accident 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apalutamide Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apalutamide Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apalutamide Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apalutamide Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apalutamide Dementia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apalutamide Depression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apalutamide Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apalutamide Disease progression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apalutamide Dyspnoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apalutamide Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apalutamide Hip fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apalutamide Hot flush 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apalutamide Interstitial lung disease 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Apalutamide Loss of consciousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apalutamide Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apalutamide Myocardial infarction 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Apalutamide Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apalutamide Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apalutamide Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apalutamide Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Apalutamide Prostate cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apalutamide Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apalutamide Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apalutamide Rash erythematous 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apalutamide Stevens-Johnson syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apalutamide Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apalutamide Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apalutamide Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apalutamide Weight decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apalutamide White blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apixaban Abasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Apixaban Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Acute coronary syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Acute hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Acute kidney injury 1.0 1.0 1.0 0.0 0.0 1.0 0.0 Apixaban Acute myeloid leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Acute myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Acute pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Acute respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apixaban Altered state of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Amnesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Anaemia 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Apixaban Anal incontinence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Angioedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Angiopathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Anxiety 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Aphasia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Apixaban Arrhythmia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apixaban Arthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Arthropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Asphyxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Asthenia 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Apixaban Asthma 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Apixaban Atelectasis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Atrial fibrillation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Atrial flutter 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Atrioventricular block complete 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Bacteraemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Bacterial infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apixaban Basal cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Blindness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apixaban Blood count abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apixaban Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apixaban Blood glucose increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Blood pressure decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apixaban Blood urea increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Blood urine present 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apixaban Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Brain injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Brain oedema 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Apixaban Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Breast disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apixaban Bronchospasm 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apixaban C-reactive protein increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Cachexia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Cardiac disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Cardiac failure acute 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Cardiac failure congestive 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Cardiac tamponade 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Cardiogenic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Cardiopulmonary failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Cardiovascular disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Cerebral haemorrhage 1.0 1.0 0.0 1.0 0.0 1.0 0.0 Apixaban Cerebral infarction 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Apixaban Cerebrovascular accident 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apixaban Chromaturia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Chronic obstructive pulmonary disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Circulatory collapse 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Coagulopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Cognitive disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Apixaban Cold sweat 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Colitis ischaemic 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Colon cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Confusional state 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Apixaban Contusion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Coronary artery disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Deafness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apixaban Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Decubitus ulcer 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Deep vein thrombosis 0.0 0.0 0.0 0.0 0.0 1.0 1.0 Apixaban Dehydration 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Apixaban Delirium 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Dementia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Depressed level of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Depressed mood 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Apixaban Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Apixaban Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Diarrhoea 0.0 0.0 1.0 0.0 0.0 1.0 0.0 Apixaban Discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Disease recurrence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apixaban Disseminated intravascular coagulation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Dizziness 0.0 1.0 1.0 1.0 0.0 1.0 0.0 Apixaban Drug hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Drug-induced liver injury 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Duodenal ulcer 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Apixaban Dysarthria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Dysgeusia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Dysphagia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Apixaban Dyspnoea 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Apixaban Dyspnoea exertional 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apixaban Dysstasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apixaban Ear disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apixaban Embolism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Embolism venous 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Apixaban Emotional distress 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Encephalopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Epilepsy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Epistaxis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Erythema multiforme 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Eye disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Eye haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Eye pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Facial paralysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Faecaloma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apixaban Faeces discoloured 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Apixaban Feeling abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Femur fracture 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Flank pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apixaban Fluid overload 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Fluid retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apixaban Full blood count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apixaban Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Gastric haemorrhage 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Apixaban Gastric ulcer 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Apixaban Gastritis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Apixaban Gastrointestinal haemorrhage 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Apixaban Gastrooesophageal reflux disease 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Generalised oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Generalised tonic-clonic seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Gout 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Haematemesis 1.0 1.0 1.0 0.0 0.0 1.0 0.0 Apixaban Haematochezia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apixaban Haematocrit decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Apixaban Haematoma 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Apixaban Haematuria 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Apixaban Haemodynamic instability 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Haemoglobin decreased 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Apixaban Haemolytic anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apixaban Haemoptysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Haemorrhage 0.0 1.0 0.0 0.0 0.0 1.0 1.0 Apixaban Haemorrhage intracranial 1.0 1.0 0.0 0.0 0.0 1.0 0.0 Apixaban Haemorrhagic stroke 1.0 1.0 0.0 0.0 0.0 1.0 0.0 Apixaban Haemorrhoids 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Hallucination 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Headache 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Apixaban Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apixaban Hemiparesis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Apixaban Hemiplegia 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Apixaban Hepatic cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Hepatic cirrhosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Hepatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Hip fracture 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Hyperbilirubinaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Hyperglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apixaban Hyperkalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Hyperlipidaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Hypertensive crisis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Hyperthyroidism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Hypoacusis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apixaban Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Hypocalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apixaban Hypoglycaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Apixaban Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Apixaban Hypophagia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Hypotension 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Apixaban Hypovolaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apixaban Hypoxia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Ileus 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Immune thrombocytopenic purpura 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Incontinence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Apixaban Inflammation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apixaban Influenza like illness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Intentional self-injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Interstitial lung disease 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Intervertebral disc protrusion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Intestinal obstruction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Intracranial pressure increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Iron deficiency anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Apixaban Irritable bowel syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Ischaemic stroke 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Apixaban Jaundice 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Apixaban Joint swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Laceration 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Apixaban Lactic acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Laryngitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Lethargy 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Apixaban Leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Leukocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Limb discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Liver function test abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Liver injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Localised infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apixaban Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Lung disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Lung infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Lymphoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Malaise 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Apixaban Malignant melanoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Malnutrition 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Apixaban Melaena 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Apixaban Memory impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Meningitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Mental impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Mental status changes 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Metabolic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Metastases to central nervous system 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Metastases to liver 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Metastases to lung 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Metastatic neoplasm 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Mobility decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Movement disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Apixaban Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Musculoskeletal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Musculoskeletal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Musculoskeletal stiffness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Myelodysplastic syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Myocardial ischaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apixaban Nausea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Apixaban Neck pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Nephrolithiasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Nervous system disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Night sweats 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Obstructive airways disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Ocular hyperaemia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Oesophagitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apixaban Osteoarthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Oxygen saturation decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Pallor 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Apixaban Pancreatic carcinoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Pancreatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Pancreatitis acute 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Paralysis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Parkinson's disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Peptic ulcer 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Pericardial effusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Pericarditis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Peripheral coldness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Peripheral ischaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Apixaban Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apixaban Peripheral vascular disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Peritonitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Petechiae 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Plasma cell myeloma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Pleural effusion 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Apixaban Pleurisy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apixaban Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Pneumonia aspiration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Pneumonia bacterial 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Pneumonitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Polyp 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apixaban Productive cough 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Apixaban Prostate cancer 1.0 1.0 0.0 0.0 0.0 0.0 1.0 Apixaban Prostatic disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Proteinuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apixaban Prothrombin time prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Pulmonary alveolar haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Pulmonary congestion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Pulmonary embolism 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Apixaban Pulmonary fibrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Pulmonary haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Pulmonary hypertension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Pulmonary mass 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Apixaban Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Rash macular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apixaban Raynaud's phenomenon 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Rectal haemorrhage 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Apixaban Renal disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Respiratory disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Respiratory distress 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Retinal detachment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Retinal haemorrhage 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apixaban Rhabdomyolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Rheumatoid arthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Shock haemorrhagic 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Sinusitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Skin cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Skin disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Skin necrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Skin ulcer 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Sleep apnoea syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Small intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apixaban Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Speech disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Spinal fracture 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Stress cardiomyopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Subarachnoid haemorrhage 1.0 1.0 0.0 0.0 0.0 1.0 0.0 Apixaban Subdural haematoma 1.0 1.0 0.0 0.0 0.0 1.0 0.0 Apixaban Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Suicidal ideation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Apixaban Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Apixaban Tachypnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apixaban Tendonitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Thrombophlebitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Thrombosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Tooth abscess 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Tooth disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Transient ischaemic attack 0.0 0.0 0.0 0.0 0.0 1.0 1.0 Apixaban Treatment failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Troponin increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Apixaban Ulcer 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Unresponsive to stimuli 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Upper gastrointestinal haemorrhage 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Apixaban Upper limb fracture 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Urinary incontinence 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Apixaban Urinary tract infection 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Apixaban Urosepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apixaban Varicose vein 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Vascular purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apixaban Venous thrombosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Ventricular fibrillation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Ventricular tachycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Apixaban Vertigo 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Apixaban Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apixaban Visual acuity reduced 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apixaban Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apixaban Vomiting 1.0 1.0 1.0 0.0 0.0 1.0 0.0 Apixaban Wheezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apomorphine hydrochloride Asthenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Apomorphine hydrochloride Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apomorphine hydrochloride Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apomorphine hydrochloride Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apomorphine hydrochloride Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apomorphine hydrochloride Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Apomorphine hydrochloride Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apomorphine hydrochloride Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apomorphine hydrochloride Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apomorphine hydrochloride Parkinson's disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apomorphine hydrochloride Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apomorphine hydrochloride Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Apomorphine hydrochloride Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apomorphine hydrochloride Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Abasia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Abdominal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Abdominal distension 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Abdominal pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Abdominal pain upper 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Abnormal dreams 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Acute myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apremilast Agitation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Alanine aminotransferase increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apremilast Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Anger 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Angiopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Appendicitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Arrhythmia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Arthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apremilast Arthropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Aspartate aminotransferase increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apremilast Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Asthma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Atrial flutter 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Back pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Bacterial infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Basal cell carcinoma 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apremilast Blindness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Blood creatinine increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apremilast Blood glucose increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Blood magnesium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Blood pressure abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Blood pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Breast disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Bronchitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Bursitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast C-reactive protein increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apremilast Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apremilast Cardiac disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Cardiac failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Carpal tunnel syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Cerebral haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Cerebral infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Cerebrovascular accident 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Cholecystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Chromaturia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Chronic kidney disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Chronic obstructive pulmonary disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Clostridium difficile infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Cold sweat 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Colon cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apremilast Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apremilast Constipation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Contusion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Coronary artery disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Crying 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Cystitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apremilast Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apremilast Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Dementia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Depressed mood 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Depression 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Apremilast Dermatitis allergic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Diplopia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Disorientation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Disturbance in attention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Diverticulitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Drug eruption 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apremilast Drug hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Drug intolerance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apremilast Dry eye 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Dry skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Dysgeusia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Dyspnoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apremilast Dysuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Ear infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Ear pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Eczema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Emotional disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Eructation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Erythema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apremilast Eye disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Eye haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Eye swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Feeding disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Feeling jittery 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Flatulence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Frequent bowel movements 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Full blood count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Fungal infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Furuncle 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apremilast Gastric disorder 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Gastrointestinal disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Gastrointestinal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Gastrooesophageal reflux disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Haematemesis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Haematochezia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Haemoptysis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Haemorrhagic stroke 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Haemorrhoids 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Hallucination 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Headache 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Heart rate increased 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Hepatic failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Hepatic steatosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Hepatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Herpes zoster 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Hip fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Hot flush 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Hypercalcaemia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apremilast Hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Hyperthyroidism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Hypoacusis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Hypothyroidism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Ill-defined disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Immune system disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apremilast Inflammation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apremilast Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Influenza like illness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Intestinal perforation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Irritability 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Joint stiffness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Joint swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Lacrimation increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Leukopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Limb discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Liver disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Localised infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Loss of consciousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Lung neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Lymphadenopathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Lymphoedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Lymphoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Malignant melanoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Malnutrition 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Mass 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Meningitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Menorrhagia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Mental impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Migraine 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Mobility decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Mood altered 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Mood swings 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apremilast Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apremilast Musculoskeletal stiffness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Myocardial infarction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Apremilast Nasal congestion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Nasopharyngitis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Nausea 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Neoplasm 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Nephropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Nervousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Neuralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apremilast Night sweats 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Nightmare 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Nodule 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Oedema peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apremilast Oral disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Oral pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Oropharyngeal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apremilast Osteoarthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Oxygen saturation decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Pain of skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Pancreatic carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Panic attack 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apremilast Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apremilast Parkinson's disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apremilast Pharyngeal oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Photophobia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Pneumothorax 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Pollakiuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Poor quality sleep 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Presyncope 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Productive cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Prostate cancer 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apremilast Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Pruritus generalised 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Psoriasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Pulmonary embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Rash 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Rash macular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Rash papular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Rash pruritic 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apremilast Rectal haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Red blood cell sedimentation rate increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apremilast Renal disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Renal failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Respiratory disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apremilast Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Apremilast Respiratory tract congestion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Respiratory tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Restlessness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Retching 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Retinal detachment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Rheumatoid arthritis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Rhinorrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Sepsis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Apremilast Septic shock 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Sinus disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Sinusitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Skin cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Skin disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apremilast Skin exfoliation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Skin irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Skin ulcer 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apremilast Sleep disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Sneezing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Somnolence 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Spinal compression fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Squamous cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Staphylococcal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Stomatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Stress 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Apremilast Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Apremilast Supraventricular tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Swelling face 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Swollen tongue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Syncope 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Systemic lupus erythematosus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Tendonitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apremilast Throat irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Tinnitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Tongue disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apremilast Treatment failure 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apremilast Tremor 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Ulcer 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apremilast Unevaluable event 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Upper respiratory tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Urosepsis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Apremilast Urticaria 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Vaginal haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Varicose vein 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Vertigo 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apremilast Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Apremilast Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Vomiting 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Weight decreased 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Apremilast Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Apremilast Wheezing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aprepitant Anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Aprepitant Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aprepitant Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aprepitant Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aprepitant Blood alkaline phosphatase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aprepitant Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aprepitant Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aprepitant Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aprepitant Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aprepitant Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aprepitant Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aprepitant Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aprepitant Flushing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aprepitant Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aprepitant Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aprepitant Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aprepitant Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aprepitant Hyponatraemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aprepitant Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aprepitant Loss of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Aprepitant Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aprepitant Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Aprepitant Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aprepitant Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aprepitant Pulmonary embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aprepitant Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aprepitant Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Aprepitant Respiratory failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aprepitant Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Aprepitant Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aprepitant Toxic epidermal necrolysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Aprepitant Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aprepitant White blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aprepitant White blood cell count increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Arformoterol tartrate Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Arformoterol tartrate Lung disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Argatroban Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Argatroban Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Argatroban Cerebral infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Argatroban Coagulopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Argatroban Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Argatroban Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Argatroban Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Argatroban Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Argatroban Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Argatroban Subarachnoid haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Argatroban Thrombosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Abdominal discomfort 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Abdominal distension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Abdominal pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Abdominal pain lower 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Abdominal pain upper 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Abnormal dreams 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Abnormal faeces 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aripiprazole Accommodation disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aripiprazole Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Acute myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Acute respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Affect lability 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Aggression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Agitation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Agranulocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Akathisia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Aripiprazole Alopecia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Altered state of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Amnesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Anal incontinence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Anger 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Angina pectoris 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Apathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Apnoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aripiprazole Arrhythmia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Arthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Arthropathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Asphyxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Asthma 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Ataxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Atrial fibrillation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Atrioventricular block first degree 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aripiprazole Atrioventricular block second degree 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Balance disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Blister 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Blood albumin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Blood cholesterol increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Blood creatine phosphokinase increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Blood creatinine increased 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Aripiprazole Blood glucose increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aripiprazole Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Blood potassium increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Blood pressure decreased 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Aripiprazole Blood pressure fluctuation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Blood pressure increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Blood urine present 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Body temperature decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aripiprazole Body temperature increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Bone pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aripiprazole Bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Bradyphrenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Brain injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aripiprazole Brain oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aripiprazole Bronchitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Burning sensation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole C-reactive protein increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Cardiac disorder 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Aripiprazole Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Cardiac failure congestive 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Cardiac murmur 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Aripiprazole Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Cardiomegaly 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Cardiomyopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Cardiovascular disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aripiprazole Catatonia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Cerebral ischaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Cerebrovascular accident 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Chest discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Chest pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Chills 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Choking 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Cholecystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Chromaturia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Chronic obstructive pulmonary disease 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Circulatory collapse 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Cognitive disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Cold sweat 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Confusional state 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Aripiprazole Congestive cardiomyopathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Contusion 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Coordination abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Cough 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Crying 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Deafness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Deep vein thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Depressed level of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Depressed mood 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Dermatitis bullous 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Diabetes mellitus 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Aripiprazole Diabetic ketoacidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Diplopia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Discomfort 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Disease recurrence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Disorientation 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Aripiprazole Disseminated intravascular coagulation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Disturbance in sexual arousal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Drug abuse 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Drug dependence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Drug intolerance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Drug reaction with eosinophilia and systemic symptoms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Drug withdrawal syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Dry mouth 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Dry skin 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Dysarthria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Dysgeusia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Dyskinesia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Aripiprazole Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Dysphagia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Dysphonia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Dysphoria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Dyspnoea 0.0 1.0 1.0 1.0 1.0 0.0 0.0 Aripiprazole Dysstasia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Dystonia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Aripiprazole Dysuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Ear pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aripiprazole Eating disorder 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Aripiprazole Ejection fraction decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Electrocardiogram abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Embolism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Embolism venous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aripiprazole Emotional disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Emotional distress 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Encephalitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Encephalopathy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Epistaxis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Erectile dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Eructation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Erythema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Euphoric mood 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Extrapyramidal disorder 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Aripiprazole Extrasystoles 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aripiprazole Eye disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Eye irritation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Eye pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Faecaloma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Fear 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Feeding disorder 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Aripiprazole Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Feeling cold 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Feeling hot 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Flatulence 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Aripiprazole Foetal growth restriction 0.0 0.0 0.0 0.0 1.0 0.0 1.0 Aripiprazole Gait disturbance 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Galactorrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aripiprazole Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Gastroenteritis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Gastrointestinal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Gastrointestinal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Gastrooesophageal reflux disease 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Generalised oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aripiprazole Gout 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Haematemesis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Haematocrit decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Haemodynamic instability 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Haemoglobin decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Hallucination, auditory 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Hallucination, visual 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Headache 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Aripiprazole Heart rate decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Heart rate increased 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Aripiprazole Heart rate irregular 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Hepatic function abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Hepatic steatosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aripiprazole Hepatomegaly 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Hirsutism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Hostility 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aripiprazole Hypercholesterolaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Hyperkalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Hyperlipidaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Hypernatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Hyperpyrexia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Hyperreflexia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Hypersomnia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Hypertension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Hyperthermia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Hyperthyroidism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aripiprazole Hypertonia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Aripiprazole Hypertriglyceridaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Hypoacusis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Hypocalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Hypoglycaemia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Hypokinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Hypothermia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Hypothyroidism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aripiprazole Hypotonia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Hypoxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Ill-defined disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Immune system disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Inappropriate antidiuretic hormone secretion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Increased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Infection 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Influenza like illness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Injection site pain 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Aripiprazole Injury 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Insomnia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Intentional self-injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Intestinal perforation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Irritability 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Ischaemic stroke 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Joint swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Lacrimation increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aripiprazole Lethargy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Leukocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Leukopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Libido decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Libido increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Lipase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Liver disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Liver injury 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Localised infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Loss of consciousness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Lung disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Lymphadenopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Mania 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Menstruation irregular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Mental disorder 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Aripiprazole Mental impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Metabolic acidosis 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Middle insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aripiprazole Migraine 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Mood altered 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Mood swings 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Motor dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Movement disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Multiple fractures 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Muscle contractions involuntary 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Muscle rigidity 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Aripiprazole Muscle spasms 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Muscle tightness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Muscle twitching 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Muscular weakness 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Aripiprazole Musculoskeletal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Musculoskeletal stiffness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Mydriasis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Myocardial ischaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Myoclonus 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Nasal congestion 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Aripiprazole Nasal dryness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Nausea 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Aripiprazole Neck pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Nervous system disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Neuroleptic malignant syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Nightmare 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Nuchal rigidity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Obesity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Ocular hyperaemia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Oral disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Osteoarthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Pain in jaw 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Pallor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Palpitations 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Pancytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Panic attack 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Paraesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Paralysis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Paranoia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Aripiprazole Parkinson's disease 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Parkinsonism 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Parosmia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Personality change 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aripiprazole Personality disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aripiprazole Pharyngeal oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Pharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Phlebitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aripiprazole Photophobia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Photosensitivity reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Pleural effusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Pneumonia aspiration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Pollakiuria 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Poor quality sleep 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Pregnancy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aripiprazole Premature baby 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Aripiprazole Productive cough 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Pruritus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Psoriasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aripiprazole Psychomotor hyperactivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Psychotic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Pulmonary congestion 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Pulmonary embolism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Pyrexia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Aripiprazole Rash 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Rash erythematous 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Rash pruritic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Red blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Renal disorder 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Renal failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Renal impairment 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Respiratory depression 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Respiratory distress 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Aripiprazole Respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Restless legs syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Restlessness 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Aripiprazole Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Rheumatoid arthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aripiprazole Rhinorrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Salivary hypersecretion 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Sciatica 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Sedation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aripiprazole Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Serotonin syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Sexual dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Sinus bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Sinus tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Skin disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Skin exfoliation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Skin irritation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Sleep apnoea syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Sleep disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Sluggishness 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Aripiprazole Somnolence 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Aripiprazole Sopor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Speech disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Status epilepticus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Stress 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Aripiprazole Stupor 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Subarachnoid haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Suicidal ideation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Suicide attempt 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Aripiprazole Supraventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Swelling face 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Swollen tongue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Syncope 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Tachypnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Tardive dyskinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Tendonitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Thinking abnormal 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Aripiprazole Thirst 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Throat irritation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Thrombosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Toothache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Torsade de pointes 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Transaminases increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Transient ischaemic attack 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aripiprazole Tremor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Unevaluable event 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Aripiprazole Unresponsive to stimuli 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Upper limb fracture 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Aripiprazole Urinary incontinence 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Aripiprazole Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Urine output decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Vaginal haemorrhage 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Ventricular arrhythmia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Ventricular fibrillation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole Vision blurred 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Visual acuity reduced 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Visual impairment 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Aripiprazole Vomiting 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Weight decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Weight increased 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Aripiprazole Wheezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole White blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole White blood cell count increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole Withdrawal syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Aripiprazole lauroxil Abnormal dreams 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Aggression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Akathisia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Anger 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Delusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Depression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Disturbance in attention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Dyskinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Emotional disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Euphoric mood 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Hallucination, auditory 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Hallucination, visual 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Hypersomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Injection site pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Mania 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Memory impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Migraine 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Panic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Paranoia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Psychotic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Restlessness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Speech disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Suicidal ideation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Suicide attempt 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Thinking abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aripiprazole lauroxil Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Armodafinil Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Armodafinil Aphasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Armodafinil Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Armodafinil Brain oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Armodafinil Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Armodafinil Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Armodafinil Deep vein thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Armodafinil Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Armodafinil Hemiparesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Armodafinil Hypoaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Armodafinil Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Armodafinil Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Armodafinil Pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Armodafinil Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Armodafinil Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Armodafinil Somnolence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Arsenic trioxide Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Arsenic trioxide Drug resistance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Arsenic trioxide Electrocardiogram QT prolonged 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Arsenic trioxide Pleural effusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Asenapine maleate Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Asenapine maleate Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Asenapine maleate Somnolence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Asenapine maleate Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atazanavir Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atazanavir Depression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Atazanavir sulfate Depression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Atazanavir sulfate Diarrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atazanavir sulfate Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atazanavir sulfate Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atazanavir sulfate Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atenolol Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atenolol Acute myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atenolol Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Atenolol Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atenolol Altered state of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Amnesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atenolol Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atenolol Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atenolol Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atenolol Angina pectoris 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Anuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atenolol Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atenolol Asthenia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Atenolol Atrial flutter 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Atrioventricular block 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atenolol Atrioventricular block complete 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atenolol Atrioventricular block first degree 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atenolol Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atenolol Balance disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Blood pressure decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atenolol Blood pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atenolol Bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atenolol Bradyphrenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Atenolol Cardiac failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atenolol Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Atenolol Cardiogenic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Atenolol Cardiotoxicity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Atenolol Cerebral ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Cerebrovascular accident 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atenolol Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Circulatory collapse 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Atenolol Coma 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atenolol Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Atenolol Confusional state 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atenolol Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atenolol Cough 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atenolol Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Atenolol Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atenolol Depressed level of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Atenolol Depressed mood 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atenolol Diarrhoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atenolol Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Atenolol Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atenolol Drug abuse 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Drug hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atenolol Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atenolol Drug-induced liver injury 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atenolol Dry eye 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atenolol Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atenolol Dry skin 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atenolol Dysgeusia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Dyspnoea exertional 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Electrocardiogram QT prolonged 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Epistaxis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atenolol Erectile dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Atenolol Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atenolol Femur fracture 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atenolol Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atenolol Gastrointestinal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atenolol Haematemesis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atenolol Haemoglobin decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atenolol Heart rate decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atenolol Hepatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atenolol Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Hot flush 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atenolol Hyperglycaemia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atenolol Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Hyperkalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atenolol Hypertension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atenolol Hypertensive crisis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atenolol Hypoglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atenolol Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atenolol Hypokinesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atenolol Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atenolol Hypothermia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atenolol Hypotonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atenolol Hypoxia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atenolol Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atenolol Interstitial lung disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Jaundice cholestatic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Joint swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atenolol Lactic acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atenolol Lethargy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atenolol Libido decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atenolol Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atenolol Loss of libido 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atenolol Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Melaena 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atenolol Metabolic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Atenolol Movement disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Multiple organ dysfunction syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atenolol Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atenolol Musculoskeletal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atenolol Musculoskeletal stiffness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atenolol Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atenolol Myocardial infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atenolol Nightmare 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atenolol Oliguria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Oxygen saturation decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Atenolol Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atenolol Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atenolol Pallor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Palpitations 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atenolol Pancreatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atenolol Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atenolol Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atenolol Pneumonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atenolol Pulmonary embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Pulmonary fibrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Pulmonary oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atenolol Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Rales 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Rash 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atenolol Rash pustular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Renal failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atenolol Respiratory depression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atenolol Respiratory distress 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Atenolol Respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atenolol Rhabdomyolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atenolol Rheumatoid arthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atenolol Shock 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atenolol Sinus bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atenolol Sleep disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atenolol Somnolence 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atenolol Subarachnoid haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Subdural haematoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Atenolol Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atenolol Suicide attempt 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atenolol Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atenolol Toxic epidermal necrolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Toxic skin eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Urinary incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Ventricular tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atenolol Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atenolol Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atomoxetine Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atomoxetine Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atomoxetine Vomiting 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atomoxetine Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atomoxetine hydrochloride Abdominal pain upper 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atomoxetine hydrochloride Aggression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atomoxetine hydrochloride Agitation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atomoxetine hydrochloride Blood pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atomoxetine hydrochloride Chest pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atomoxetine hydrochloride Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Atomoxetine hydrochloride Crying 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atomoxetine hydrochloride Decreased appetite 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atomoxetine hydrochloride Depressed mood 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atomoxetine hydrochloride Depression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atomoxetine hydrochloride Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atomoxetine hydrochloride Erectile dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atomoxetine hydrochloride Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atomoxetine hydrochloride Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atomoxetine hydrochloride Hallucination 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atomoxetine hydrochloride Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atomoxetine hydrochloride Hyperhidrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atomoxetine hydrochloride Hypoaesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atomoxetine hydrochloride Insomnia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atomoxetine hydrochloride Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atomoxetine hydrochloride Mental disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atomoxetine hydrochloride Mood swings 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atomoxetine hydrochloride Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atomoxetine hydrochloride Pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atomoxetine hydrochloride Paraesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atomoxetine hydrochloride Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atomoxetine hydrochloride Raynaud's phenomenon 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atomoxetine hydrochloride Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atomoxetine hydrochloride Sleep disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atomoxetine hydrochloride Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Atomoxetine hydrochloride Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atomoxetine hydrochloride Urinary retention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atomoxetine hydrochloride Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atomoxetine hydrochloride Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Abasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Abdominal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Atorvastatin Abdominal distension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Abdominal pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Abdominal pain upper 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Abnormal dreams 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atorvastatin Acute kidney injury 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Atorvastatin Acute myocardial infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Aggression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atorvastatin Alanine aminotransferase increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Atorvastatin Amnesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Aphasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Arthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Arthropathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Aspartate aminotransferase increased 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Atorvastatin Asthenia 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Atorvastatin Asthma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atorvastatin Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Balance disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Blindness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atorvastatin Blister 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Blood alkaline phosphatase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Blood cholesterol increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Blood creatine phosphokinase increased 0.0 1.0 1.0 1.0 0.0 1.0 0.0 Atorvastatin Blood creatinine increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Blood glucose increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Blood pressure decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Blood triglycerides increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atorvastatin Bone pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Cardiac arrest 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Cardiac disorder 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Atorvastatin Cardiac failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Cardiomyopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Cataract 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Cerebral haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Chest discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Chest pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Chills 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Cholecystitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Chromaturia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Chronic obstructive pulmonary disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Circulatory collapse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Coagulopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Cognitive disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Cold sweat 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Colitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Confusional state 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Contusion 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Atorvastatin Coronary artery disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Cough 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Deafness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Atorvastatin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Decreased appetite 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Delirium 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Dementia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Dermatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Diabetes mellitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Diabetic ketoacidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Diarrhoea 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Atorvastatin Diplopia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Drug hypersensitivity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Drug intolerance 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Atorvastatin Drug-induced liver injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Dysarthria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Dysphagia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Dysphonia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Dyspnoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Dyspnoea exertional 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Dysstasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Epigastric discomfort 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Erectile dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Atorvastatin Eructation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Erythema 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Eye irritation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Eye swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atorvastatin Eyelid oedema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Face oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Faeces discoloured 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Feeling cold 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Feeling hot 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Flatulence 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Atorvastatin Gait disturbance 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Gallbladder disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atorvastatin Gamma-glutamyltransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Gastrointestinal haemorrhage 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Gout 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Haemoglobin decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Haemoptysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Haemorrhage intracranial 1.0 0.0 1.0 1.0 0.0 0.0 0.0 Atorvastatin Hallucination 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Atorvastatin Hallucination, visual 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Headache 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Atorvastatin Heart rate increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Hepatic cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Hepatic cirrhosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Hepatic enzyme increased 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Atorvastatin Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Hepatic function abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Hepatitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Hepatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Hepatitis cholestatic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Hepatocellular injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Hepatomegaly 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Hernia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Hot flush 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Hypercalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Hyperglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Hyperkalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Hypoacusis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Hypoglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Hypokinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Hypotension 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Atorvastatin Hypoxia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Influenza 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Influenza like illness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Interstitial lung disease 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Joint swelling 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Atorvastatin Lacrimation increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atorvastatin Lethargy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Libido decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atorvastatin Limb discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Lip swelling 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Atorvastatin Lipase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Liver disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Liver function test abnormal 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Liver injury 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Local swelling 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Lung disorder 1.0 0.0 1.0 1.0 0.0 0.0 0.0 Atorvastatin Malaise 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Melaena 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Mental disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atorvastatin Mental impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Metabolic acidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Migraine 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Mobility decreased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Movement disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Muscle atrophy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Atorvastatin Muscle twitching 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Muscular weakness 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Atorvastatin Musculoskeletal chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Musculoskeletal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Musculoskeletal stiffness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Myalgia 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Atorvastatin Myocardial infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Myopathy 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Atorvastatin Myositis 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Atorvastatin Nasopharyngitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Nausea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Neck pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Nephropathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Nervous system disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Neuralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Nightmare 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Atorvastatin Oedema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Oropharyngeal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Orthostatic hypotension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Osteoarthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atorvastatin Pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Palpitations 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Pancreatitis acute 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Atorvastatin Pancytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Paralysis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Peripheral coldness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atorvastatin Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Pharyngeal oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Pneumonia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Pollakiuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Polyneuropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atorvastatin Poor quality sleep 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Pulmonary embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Pulmonary fibrosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Rash 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Rash generalised 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Rash macular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atorvastatin Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Rash pruritic 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Red blood cell sedimentation rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Renal failure 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Renal impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Renal tubular necrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Restless legs syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Atorvastatin Sensory loss 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atorvastatin Sepsis 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Skin discolouration 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Skin ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Sleep disorder 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Atorvastatin Somnolence 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Speech disorder 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Atorvastatin Subarachnoid haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Suicidal ideation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atorvastatin Suicide attempt 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Swelling face 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atorvastatin Syncope 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Atorvastatin Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Tendon rupture 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Tendonitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Throat irritation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Thrombocytopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Transaminases increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Transient ischaemic attack 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Tremor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin Urinary tract infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Ventricular fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Visual acuity reduced 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atorvastatin Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Vomiting 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Atorvastatin Weight decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin Weight increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin White blood cell count increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin calcium Abdominal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atorvastatin calcium Abdominal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin calcium Agitation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin calcium Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Amnesia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Atorvastatin calcium Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin calcium Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Arthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Blood creatine phosphokinase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin calcium Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin calcium Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin calcium Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin calcium Chest pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin calcium Cognitive disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Confusional state 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atorvastatin calcium Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Drug interaction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin calcium Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Dysphagia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Eczema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin calcium Erectile dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Atorvastatin calcium Face oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin calcium Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Flatulence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Generalised oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin calcium Glaucoma 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Atorvastatin calcium Headache 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Atorvastatin calcium Hepatic enzyme increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atorvastatin calcium Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin calcium Hepatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin calcium Hyperglycaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atorvastatin calcium Hyperhidrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin calcium Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Hypoglycaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin calcium Infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin calcium Influenza 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin calcium Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Ischaemic stroke 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin calcium Jaundice cholestatic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin calcium Joint swelling 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Atorvastatin calcium Liver function test abnormal 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin calcium Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin calcium Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin calcium Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Atorvastatin calcium Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Mood swings 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atorvastatin calcium Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Musculoskeletal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Musculoskeletal stiffness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Myopathy 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Myositis 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Nasopharyngitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Neck pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Nephrolithiasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atorvastatin calcium Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Atorvastatin calcium Nightmare 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Photosensitivity reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atorvastatin calcium Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin calcium Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin calcium Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin calcium Renal impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin calcium Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin calcium Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin calcium Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin calcium Tendon rupture 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin calcium Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Transaminases increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Atorvastatin calcium Urinary tract infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atorvastatin calcium Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Atorvastatin calcium Vomiting 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Atorvastatin calcium Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Atovaquone Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Atovaquone Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atovaquone Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atovaquone Pyrexia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atracurium Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atracurium Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atracurium besylate Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atracurium besylate Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atracurium besylate Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atracurium besylate Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Atracurium besylate Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atracurium besylate Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atracurium besylate Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atracurium besylate Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atropine Atrial fibrillation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atropine Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Atropine Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atropine sulfate Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atropine sulfate Cardiac arrest 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Atropine sulfate Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atropine sulfate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Atropine sulfate Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Atropine sulfate Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Atropine sulfate Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Auranofin Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Auranofin Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Abdominal distension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Abdominal pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Abdominal pain lower 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Acute coronary syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Acute myocardial infarction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Acute respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Altered state of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Aphasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Appendicitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Asthenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Atrial flutter 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Back pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Blood bilirubin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Blood creatine phosphokinase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Blood potassium increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Blood pressure decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Cardiac disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Axitinib Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Cerebral infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Cerebral ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Cerebrovascular accident 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Cholecystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Chromaturia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Cognitive disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Axitinib Confusional state 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Constipation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Axitinib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Decreased appetite 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Deep vein thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Diabetes mellitus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Axitinib Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Drug hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Dysgeusia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Dysphagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Dysphonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Dyspnoea exertional 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Encephalopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Epilepsy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Fatigue 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Gamma-glutamyltransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Gastric disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Gastrointestinal disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Haematemesis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Haematuria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Haemoglobin decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Haemoptysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Heart rate decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Hemiparesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Hepatic function abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Hepatocellular injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Axitinib Hepatotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Axitinib Hypercalcaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Hypocalcaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Hypophagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Ileus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Interstitial lung disease 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Axitinib Ischaemic stroke 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Jaundice 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Axitinib Joint swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Axitinib Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Axitinib Malaise 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Malnutrition 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Mental disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Mental impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Axitinib Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Mouth ulceration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Muscular weakness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Axitinib Nasopharyngitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Nausea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Nervous system disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Oedema peripheral 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Oral pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Oropharyngeal pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Peritonitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Platelet count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Axitinib Pleural effusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Pneumonia bacterial 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Pneumonitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Pneumothorax 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Posterior reversible encephalopathy syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Axitinib Proteinuria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Pulmonary embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Rash erythematous 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Rash macular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Renal failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Axitinib Respiratory disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Axitinib Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Sepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Axitinib Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Sinusitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Skin disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Axitinib Somnolence 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Speech disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Stomatitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Subarachnoid haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Axitinib Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Thrombosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Transient ischaemic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Upper gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Urinary retention 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Axitinib Urinary tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Urticaria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Vomiting 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Weight decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Axitinib Weight increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Abdominal distension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Abdominal pain 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Abdominal pain upper 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Abscess 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Acute coronary syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Azacitidine Acute kidney injury 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Azacitidine Acute myeloid leukaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Acute myocardial infarction 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Azacitidine Acute pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Acute respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Agranulocytosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Alanine aminotransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Altered state of consciousness 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Azacitidine Anaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Angina pectoris 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Appendicitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Arthritis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Aspartate aminotransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Asthenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Atelectasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Atrial fibrillation 1.0 1.0 1.0 1.0 0.0 0.0 0.0 Azacitidine Back pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Bacteraemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Bacterial infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Azacitidine Blood alkaline phosphatase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Blood bilirubin increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Blood creatinine increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Blood disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Blood lactate dehydrogenase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Blood pressure decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Blood urea increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Bone marrow failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Bone pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Bronchitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Bursitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine C-reactive protein increased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Cachexia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Candida infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Cardiac disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Cardiac failure acute 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Cardiac failure congestive 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Cardiogenic shock 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Azacitidine Cardiopulmonary failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Cardiovascular disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Azacitidine Cellulitis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Cerebral haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Cerebral infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Cerebrovascular accident 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Azacitidine Chest pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Chills 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Cholangitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Cholecystitis 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Azacitidine Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Chronic kidney disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Chronic obstructive pulmonary disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Circulatory collapse 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Clostridium difficile colitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Clostridium difficile infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Colitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Colitis ischaemic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Colon cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Coma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Confusional state 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Constipation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Contusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Cough 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Deep vein thrombosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Dehydration 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Delirium 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Azacitidine Depressed level of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Diarrhoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Disease recurrence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Disseminated intravascular coagulation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Diverticulitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Dizziness 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Drug intolerance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Drug resistance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Azacitidine Dyspnoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Dyspnoea exertional 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Electrocardiogram QT prolonged 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Encephalitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Enteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Enterocolitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Epistaxis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Erythema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Face oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Fatigue 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Febrile neutropenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Femur fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Full blood count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Fungal infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Gamma-glutamyltransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Gastric cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Gastroenteritis 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Azacitidine Gastrointestinal disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Gastrointestinal haemorrhage 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Generalised oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Gingival bleeding 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Haematemesis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Haematuria 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Haemoglobin decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Haemolysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Haemoptysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Haemorrhage intracranial 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Haemorrhagic stroke 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Haemorrhoids 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Headache 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Hepatic cirrhosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Hepatotoxicity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Herpes zoster 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Hip fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Hyperbilirubinaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Hyperkalaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Hypertension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Hypokalaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Hyponatraemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Hypotension 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Hypovolaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Hypoxia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Ileus 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Immune system disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Influenza 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Injection site pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Injection site reaction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Insomnia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Interstitial lung disease 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Intestinal obstruction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Ischaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Ischaemic stroke 1.0 0.0 1.0 1.0 0.0 0.0 0.0 Azacitidine Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Joint swelling 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Large intestine perforation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Left ventricular dysfunction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Leukocytosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Leukopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Liver disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Loss of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Lower respiratory tract infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Lung disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Lung infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Lung infiltration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Malaise 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Melaena 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Azacitidine Metabolic disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Mucosal inflammation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Musculoskeletal disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Musculoskeletal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Myalgia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Myelodysplastic syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Myocardial ischaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Myositis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Nasopharyngitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Nausea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Neck pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Azacitidine Neoplasm 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Nervous system disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Neutrophil count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Night sweats 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Oedema peripheral 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Oesophagitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Osteoarthritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Osteomyelitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Oxygen saturation decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Pancytopenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Pericardial effusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Pericarditis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Pharyngitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Platelet count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Pleural effusion 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Pleurisy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Pneumocystis jirovecii pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Pneumonia bacterial 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Pneumonitis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Pneumothorax 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Proctalgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Productive cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Pruritus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Pseudomembranous colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Pulmonary alveolar haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Pulmonary embolism 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Pulmonary haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Pulmonary oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Pyrexia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Rash 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Rectal haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Red blood cell count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Renal disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Renal failure 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Azacitidine Renal impairment 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Respiratory disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Respiratory distress 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Respiratory tract infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Sinusitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Skin disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Skin exfoliation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Azacitidine Skin infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Skin lesion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Skin necrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Skin reaction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Small intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Splenomegaly 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Staphylococcal infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Stomatitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Subarachnoid haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Subdural haematoma 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Azacitidine Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Supraventricular tachycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Syncope 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Thrombophlebitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Tooth abscess 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Toothache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Transaminases increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Treatment failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Troponin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Tumour lysis syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Unevaluable event 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Upper gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Upper limb fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Upper respiratory tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Urinary incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Urinary tract infection 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Urosepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Urticaria 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Venous thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Vertigo 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Azacitidine Vomiting 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine Weight decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azacitidine White blood cell count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azacitidine White blood cell count increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azathioprine Abdominal distension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Azathioprine Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Azathioprine Abdominal pain lower 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azathioprine Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Azathioprine Acute hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azathioprine Acute kidney injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Azathioprine Acute myeloid leukaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azathioprine Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Azathioprine Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Azathioprine Aphasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azathioprine Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Azathioprine Atrial septal defect 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Azathioprine Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azathioprine Basal cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Azathioprine Bone marrow failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azathioprine C-reactive protein increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azathioprine Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azathioprine Cerebrovascular accident 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azathioprine Chills 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Azathioprine Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azathioprine Clostridium difficile colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azathioprine Colitis ulcerative 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azathioprine Crohn's disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azathioprine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azathioprine Diarrhoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Azathioprine Disease progression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Azathioprine Disease recurrence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Azathioprine Drug hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azathioprine Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Azathioprine Drug reaction with eosinophilia and systemic symptoms 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Azathioprine Febrile neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azathioprine Foetal death 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Azathioprine Gingival bleeding 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azathioprine Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azathioprine Haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Azathioprine Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azathioprine Hepatitis cholestatic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azathioprine Herpes zoster 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Azathioprine Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Azathioprine Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azathioprine Intestinal obstruction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Azathioprine Large intestine perforation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azathioprine Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Azathioprine Lipase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azathioprine Lymphopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Azathioprine Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azathioprine Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azathioprine Myelodysplastic syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azathioprine Myocarditis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Azathioprine Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Azathioprine Night sweats 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azathioprine Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azathioprine Pancytopenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Azathioprine Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Azathioprine Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Azathioprine Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Azathioprine Red blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azathioprine Renal impairment 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azathioprine Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azathioprine Rheumatoid arthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Azathioprine Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azathioprine Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azathioprine Skin cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Azathioprine Speech disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azathioprine Splenomegaly 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azathioprine Squamous cell carcinoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azathioprine Staphylococcal infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azathioprine Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azathioprine Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Azathioprine Treatment failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Azathioprine Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azathioprine Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Azathioprine Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Azathioprine White blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azathioprine White blood cell count increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azelastine hydrochloride Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Azilsartan kamedoxomil Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Azilsartan kamedoxomil Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Azithromycin Abdominal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Azithromycin Acute kidney injury 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Azithromycin Agranulocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azithromycin Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Azithromycin Atrial fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Azithromycin Blister 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Azithromycin Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azithromycin Bradycardia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Azithromycin C-reactive protein increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azithromycin Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azithromycin Chest pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Azithromycin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azithromycin Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Azithromycin Drug interaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Azithromycin Drug reaction with eosinophilia and systemic symptoms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azithromycin Dysphagia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Azithromycin Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Azithromycin Electrocardiogram QT prolonged 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azithromycin Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azithromycin Erythema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azithromycin Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azithromycin Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azithromycin Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azithromycin Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Azithromycin Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Azithromycin Myalgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azithromycin Oral candidiasis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Azithromycin Pyrexia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Azithromycin Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azithromycin Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azithromycin Stevens-Johnson syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Azithromycin Swollen tongue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azithromycin Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Azithromycin Thrombocytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azithromycin Torsade de pointes 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Azithromycin Toxic epidermal necrolysis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Azithromycin Urticaria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azithromycin Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Azithromycin Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Azithromycin dihydrate Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Azithromycin dihydrate Arthralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Azithromycin dihydrate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azithromycin dihydrate Diarrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azithromycin dihydrate Dyspnoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Azithromycin dihydrate Hepatic failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azithromycin dihydrate Hepatic function abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azithromycin dihydrate Seizure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Azithromycin dihydrate Syncope 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Azithromycin dihydrate Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Azithromycin dihydrate Vomiting 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Aztreonam Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Aztreonam Drug hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Aztreonam Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Abasia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Abdominal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Abdominal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Acute respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Aggression 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Agitation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Akathisia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Altered state of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Amnesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Baclofen Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Anuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Aphasia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Apnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Arrhythmia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Baclofen Asphyxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Baclofen Aspiration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Asthenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Atelectasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Back pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Baclofen Bacteraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Bacterial infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Blister 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Baclofen Blood creatine phosphokinase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Blood potassium decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Blood pressure decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Blood pressure increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Blood sodium decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Blood urea increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Baclofen Body temperature decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Body temperature increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Brain injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Brain oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Baclofen Burning sensation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen C-reactive protein increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Cardiac disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Baclofen Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Cardiogenic shock 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Catatonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Cerebrovascular accident 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Chronic obstructive pulmonary disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Baclofen Cognitive disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Baclofen Cold sweat 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Coma 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Baclofen Confusional state 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Constipation 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Baclofen Coordination abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Baclofen Decreased appetite 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Deep vein thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Delirium 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Delusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Depressed level of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Diarrhoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Baclofen Disorientation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Disseminated intravascular coagulation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Disturbance in attention 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Drug abuse 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Drug hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Drug intolerance 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Drug withdrawal syndrome 0.0 1.0 1.0 0.0 0.0 0.0 1.0 Baclofen Dysarthria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Dyskinesia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Dysphagia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Dystonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Emotional distress 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Encephalitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Encephalopathy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Euphoric mood 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Baclofen Eye disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Feeling abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Femur fracture 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Baclofen Gait disturbance 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Baclofen Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Generalised tonic-clonic seizure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Haematoma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Haemodynamic instability 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Haemoglobin decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Hallucination 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Hallucination, auditory 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Hallucination, visual 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Heart rate decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Heart rate increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Baclofen Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Hyperkalaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Hypernatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Hypersomnia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Hypertension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Hypertensive crisis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Hyperthermia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Hypertonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Hypoaesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Baclofen Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Hyporeflexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Hypothermia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Hypotonia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Hypoxia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Insomnia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Intentional self-injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Irritability 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Joint swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Baclofen Lactic acidosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Baclofen Lethargy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Leukocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Loss of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Lung disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Baclofen Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Mania 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Baclofen Memory impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Mental status changes 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Baclofen Metabolic acidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Baclofen Miosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Mobility decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Baclofen Motor dysfunction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Muscle atrophy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Baclofen Muscle rigidity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Muscle spasms 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Baclofen Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Baclofen Musculoskeletal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Baclofen Myalgia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Mydriasis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Myoclonus 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Neck pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Baclofen Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Nervous system disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Neuralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Baclofen Neuropathy peripheral 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Neurotoxicity 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Nightmare 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Nystagmus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Oedema peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Baclofen Osteoarthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Baclofen Osteomyelitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Oxygen saturation decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Baclofen Paraesthesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Paralysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Peripheral ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Peripheral swelling 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Pneumonia aspiration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Poor quality sleep 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Psychotic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Pulmonary embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Baclofen Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Renal failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Respiratory depression 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Respiratory disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Baclofen Respiratory distress 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Respiratory failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Restlessness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Sciatica 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Baclofen Sedation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Seizure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Sepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Sinus bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Sleep apnoea syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Baclofen Sleep disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Somnolence 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Sopor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Speech disorder 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Status epilepticus 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Stress cardiomyopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Stupor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Subarachnoid haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Suicide attempt 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Swelling 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Swelling face 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Tachypnoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Transient ischaemic attack 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Baclofen Treatment failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Baclofen Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Troponin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baclofen Unevaluable event 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Unresponsive to stimuli 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Urinary tract infection 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Urosepsis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Visual impairment 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Baclofen Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Weight decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baclofen Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Baclofen White blood cell count increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baclofen Withdrawal syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baloxavir marboxil Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baloxavir marboxil Acute kidney injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Baloxavir marboxil Altered state of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baloxavir marboxil Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baloxavir marboxil Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baloxavir marboxil Blood creatine phosphokinase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baloxavir marboxil Bronchitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Baloxavir marboxil Cardiac failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baloxavir marboxil Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Baloxavir marboxil Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Baloxavir marboxil Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baloxavir marboxil Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baloxavir marboxil Delirium 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Baloxavir marboxil Diarrhoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baloxavir marboxil Disseminated intravascular coagulation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Baloxavir marboxil Encephalopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baloxavir marboxil Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Baloxavir marboxil Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baloxavir marboxil Hepatic function abnormal 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baloxavir marboxil Hyperkalaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Baloxavir marboxil Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Baloxavir marboxil Influenza 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Baloxavir marboxil Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baloxavir marboxil Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Baloxavir marboxil Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Baloxavir marboxil Pneumonia bacterial 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Baloxavir marboxil Renal impairment 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baloxavir marboxil Restlessness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baloxavir marboxil Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baloxavir marboxil Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baricitinib Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baricitinib Alanine aminotransferase increased 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Baricitinib Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Baricitinib Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baricitinib Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Baricitinib Cerebral infarction 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Baricitinib Chest pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Baricitinib Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baricitinib Death 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Baricitinib Deep vein thrombosis 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Baricitinib Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baricitinib Diverticulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baricitinib Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baricitinib Dyspnoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Baricitinib Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baricitinib Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baricitinib Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baricitinib Herpes zoster 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Baricitinib Hypertension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Baricitinib Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Baricitinib Infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Baricitinib Interstitial lung disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Baricitinib Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baricitinib Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Baricitinib Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baricitinib Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Baricitinib Pulmonary embolism 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Baricitinib Pyrexia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Baricitinib Rheumatoid arthritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baricitinib Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Baricitinib Thrombosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Baricitinib Urinary tract infection 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Baricitinib Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Baricitinib Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Barium sulfate Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Beclomethasone Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Beclomethasone dipropionate Asthma 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Beclomethasone dipropionate Chest discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Beclomethasone dipropionate Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Beclomethasone dipropionate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Beclomethasone dipropionate Dysphonia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Beclomethasone dipropionate Dyspnoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Beclomethasone dipropionate Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Beclomethasone dipropionate Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Beclomethasone dipropionate Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Beclomethasone dipropionate Oropharyngeal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Beclomethasone dipropionate Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Beclomethasone dipropionate Throat tightness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Beclomethasone dipropionate Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bedaquiline Alanine aminotransferase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bedaquiline Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bedaquiline Arthralgia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bedaquiline Aspartate aminotransferase increased 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Bedaquiline Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bedaquiline Chest pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bedaquiline Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bedaquiline Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bedaquiline Diarrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bedaquiline Dizziness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bedaquiline Electrocardiogram QT prolonged 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bedaquiline Electrolyte imbalance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bedaquiline Gastrointestinal disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bedaquiline Haemoptysis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bedaquiline Hepatic enzyme increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bedaquiline Hepatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bedaquiline Hepatotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bedaquiline Hypokalaemia 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Bedaquiline Nausea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bedaquiline Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bedaquiline Treatment failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bedaquiline Vomiting 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bedaquiline fumarate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bedaquiline fumarate Decreased appetite 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bedaquiline fumarate Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bedaquiline fumarate Hepatotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bedaquiline fumarate Nausea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Belinostat Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Belinostat Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Belinostat Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Belinostat Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Belinostat Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Benazepril hydrochloride Angioedema 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Benazepril hydrochloride Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Benazepril hydrochloride Blood urea increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Benazepril hydrochloride Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Benazepril hydrochloride Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Benazepril hydrochloride Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Benazepril hydrochloride Hyperkalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Benazepril hydrochloride Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Benazepril hydrochloride Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Benazepril hydrochloride Shock 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Benazepril hydrochloride Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bendamustine Acute kidney injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bendamustine Anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bendamustine Anaphylactic reaction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bendamustine Asthenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bendamustine Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bendamustine Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bendamustine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bendamustine Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bendamustine Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bendamustine Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bendamustine Dyspnoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bendamustine Febrile neutropenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bendamustine Hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bendamustine Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bendamustine Hypoxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bendamustine Lymphopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bendamustine Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bendamustine Pancytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bendamustine Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bendamustine Pneumocystis jirovecii pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bendamustine Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bendamustine Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bendamustine Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bendamustine Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bendamustine Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bendamustine Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bendamustine Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bendamustine Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bendamustine Tumour lysis syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bendamustine Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Abdominal pain upper 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Asthenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Bone marrow failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Decreased appetite 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Diarrhoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Dyspnoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Erythema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Febrile neutropenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Headache 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Herpes simplex 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Herpes zoster 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Hypokalaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Hypotension 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Mucosal inflammation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Myelodysplastic syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Neutrophil count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Platelet count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Pyrexia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Rash 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Sinusitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Tachycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Tumour lysis syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Upper respiratory tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Urinary tract infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bendamustine hydrochloride Weight decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bendroflumethiazide Drug interaction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bendroflumethiazide Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Benzocaine Cyanosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Benzocaine Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Benzonatate Brain injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Benzonatate Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Benzonatate Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Benzonatate Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Benzonatate Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Benzonatate Metabolic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Benzonatate Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Benzonatate Seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Benzonatate Unresponsive to stimuli 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Benzoyl peroxide Dry skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Benzoyl peroxide Erythema 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Benzoyl peroxide Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Benzoyl peroxide Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Benzoyl peroxide Skin exfoliation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Benztropine Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Benztropine mesylate Hyperthermia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Besifloxacin Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Betaine Brain oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Betaine Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Betamethasone Abdominal distension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Betamethasone Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Betamethasone Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Betamethasone Erythema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Betamethasone Hypertension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Betamethasone Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Betamethasone Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Betamethasone Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Betamethasone Osteonecrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Betamethasone Osteoporosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Betamethasone Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Betamethasone Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Betamethasone Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Betamethasone Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Betamethasone Psychotic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Betamethasone Pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Betamethasone Skin exfoliation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Betamethasone Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Betamethasone Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Betamethasone dipropionate Erythema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Betamethasone dipropionate Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Betamethasone dipropionate Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Betamethasone dipropionate Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Betamethasone valerate Dry skin 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Betamethasone valerate Erythema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bexarotene Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bexarotene Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bexarotene Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bexarotene Hypertriglyceridaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bexarotene Hypothyroidism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bexarotene Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bexarotene Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bicalutamide Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Acute coronary syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bicalutamide Acute hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bicalutamide Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Acute myeloid leukaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bicalutamide Acute myocardial infarction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Acute respiratory distress syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Anaemia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Bicalutamide Angina pectoris 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Arrhythmia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bicalutamide Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Atrial flutter 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Atrioventricular block first degree 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bicalutamide Cardiac failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Cerebrovascular accident 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Chronic obstructive pulmonary disease 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Bicalutamide Confusional state 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bicalutamide Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Dehydration 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bicalutamide Diarrhoea 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Bicalutamide Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bicalutamide Disorientation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bicalutamide Diverticulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Dry skin 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Dyspnoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Bicalutamide Dyspnoea exertional 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bicalutamide Eosinophilia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bicalutamide Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bicalutamide Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bicalutamide Feeling abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bicalutamide Femur fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Gait disturbance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bicalutamide Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Hemiparesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bicalutamide Hip fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Hot flush 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bicalutamide Hyperglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Hyperhidrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bicalutamide Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Hypoglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bicalutamide Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Influenza like illness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Insomnia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Bicalutamide Interstitial lung disease 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bicalutamide Ischaemic stroke 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Lung infiltration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Lung neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bicalutamide Malaise 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bicalutamide Malignant neoplasm progression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bicalutamide Melaena 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Myocardial infarction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Nausea 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Bicalutamide Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Nephrotic syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Osteoporosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bicalutamide Pallor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bicalutamide Pancytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Paraesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bicalutamide Platelet count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Prostate cancer 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Bicalutamide Pulmonary embolism 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Pulmonary fibrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bicalutamide Pulmonary hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Renal impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bicalutamide Sepsis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Somnolence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bicalutamide Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Torsade de pointes 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bicalutamide Unresponsive to stimuli 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Ventricular fibrillation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bicalutamide Weight decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bimatoprost Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bimatoprost Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bimatoprost Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bimatoprost Cataract 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Bimatoprost Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bimatoprost Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bimatoprost Dry eye 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bimatoprost Dyspnoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bimatoprost Eye disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bimatoprost Eye haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bimatoprost Eye irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bimatoprost Eye pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bimatoprost Eye pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bimatoprost Eye swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bimatoprost Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bimatoprost Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bimatoprost Hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bimatoprost Intraocular pressure increased 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Bimatoprost Lacrimation increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bimatoprost Malaise 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bimatoprost Ocular hyperaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bimatoprost Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bimatoprost Visual acuity reduced 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bimatoprost Visual field defect 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bimatoprost Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Bisacodyl Muscle spasms 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bisoprolol Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Abdominal pain upper 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Acute coronary syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Acute generalised exanthematous pustulosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Acute myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Acute pulmonary oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Acute respiratory failure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Agitation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bisoprolol Altered state of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Amnesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Anuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol Appetite disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Arrhythmia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Arthralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bisoprolol Ascites 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Asthenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Atrial fibrillation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Atrial flutter 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Atrial septal defect 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Bisoprolol Atrioventricular block 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Atrioventricular block complete 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Atrioventricular block first degree 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Atrioventricular block second degree 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Back pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Balance disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol Basal cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bisoprolol Blister 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Blood bilirubin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Blood creatinine increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Blood glucose increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Bone pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bisoprolol Bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Bronchospasm 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol C-reactive protein increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Cardiac disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Cardiac failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Cardiac failure congestive 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Cardiogenic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Cerebral haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Chest discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol Chest pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Chronic obstructive pulmonary disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Circulatory collapse 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Cognitive disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol Cold sweat 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Constipation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bisoprolol Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Depressed level of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol Dermatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Dermatitis bullous 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol Discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol Dizziness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Drug abuse 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Drug hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bisoprolol Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bisoprolol Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Drug withdrawal syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Dry eye 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol Dyspnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Dyspnoea exertional 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Dysstasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol Eczema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Ejection fraction decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Electrocardiogram abnormal 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Electrolyte imbalance 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Epistaxis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Erectile dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol Eye pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bisoprolol Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol Feeding disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol Foetal growth restriction 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Bisoprolol Fracture 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Gait disturbance 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Bisoprolol Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Gastrointestinal disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Gastrointestinal haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Haematemesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Haematoma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Haemoptysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol Heart rate decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Heart rate increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol Hepatic failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Hepatic function abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Hepatitis fulminant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Hot flush 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol Hyperkalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Hypersensitivity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol Hypoacusis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bisoprolol Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol Hypocalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Hypoglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Hypomagnesaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Hypoxia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Insomnia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Intentional self-injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Interstitial lung disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Ischaemic stroke 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Jaundice 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Joint swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bisoprolol Laceration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Lactic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Lethargy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol Loss of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Lower respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Lung disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Malaise 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Melaena 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Mental impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bisoprolol Metabolic acidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Mitral valve incompetence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Mobility decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Musculoskeletal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol Neuralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Nightmare 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol Pallor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Pancreatitis acute 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Pancytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol Peripheral coldness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol Pleural effusion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Pneumonia aspiration 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Pneumothorax 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Polyuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 1.0 Bisoprolol Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Pulmonary oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Rash 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Raynaud's phenomenon 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bisoprolol Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Renal failure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Renal impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Respiratory distress 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Respiratory failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Respiratory tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Restlessness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Rhabdomyolysis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Rhinorrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bisoprolol Seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Sensory disturbance 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Septic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Shock haemorrhagic 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Sinus bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Skin disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Sneezing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bisoprolol Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Sopor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Speech disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol Stress 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bisoprolol Stress cardiomyopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Subarachnoid haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Subdural haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Suicidal ideation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Syncope 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Systemic lupus erythematosus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bisoprolol Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Tinnitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bisoprolol Tongue oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Torsade de pointes 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Transient ischaemic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Unresponsive to stimuli 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Urinary incontinence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Ventricular arrhythmia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Ventricular extrasystoles 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Ventricular fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol Vertigo 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Bisoprolol Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bisoprolol Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Weight increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol Wheezing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol fumarate Agranulocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol fumarate Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol fumarate Arrhythmia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol fumarate Arthralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bisoprolol fumarate Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol fumarate Bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol fumarate Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol fumarate Constipation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bisoprolol fumarate Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol fumarate Dyspnoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol fumarate Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol fumarate Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol fumarate Hypoaesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bisoprolol fumarate Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol fumarate Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bisoprolol fumarate Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol fumarate Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bisoprolol fumarate Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol fumarate Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol fumarate Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol fumarate Peripheral coldness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bisoprolol fumarate Psoriasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bisoprolol fumarate Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bisoprolol fumarate Syncope 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol fumarate Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bisoprolol fumarate Tremor 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bisoprolol fumarate Vertigo 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bisoprolol fumarate Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bivalirudin Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bivalirudin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bivalirudin Gastrointestinal haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bivalirudin Haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bivalirudin Thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bleomycin sulfate Chills 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bleomycin sulfate Dyspnoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bleomycin sulfate Erythema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bleomycin sulfate Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bleomycin sulfate Interstitial lung disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bleomycin sulfate Pneumonitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bleomycin sulfate Pulmonary fibrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bleomycin sulfate Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bleomycin sulfate Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Boceprevir Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Boceprevir Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Boceprevir Agitation 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Boceprevir Anaemia 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Boceprevir Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Boceprevir Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Boceprevir Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Boceprevir Dehydration 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Boceprevir Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Boceprevir Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Boceprevir Disturbance in attention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Boceprevir Dysgeusia 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Boceprevir Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Boceprevir Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Boceprevir Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Boceprevir Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Boceprevir Irritability 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Boceprevir Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Boceprevir Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Boceprevir Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Boceprevir Muscle spasms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Boceprevir Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Boceprevir Neutropenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Boceprevir Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Boceprevir Panic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Boceprevir Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Boceprevir Rash 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Boceprevir Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Boceprevir Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Boceprevir Thrombocytopenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Boceprevir Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Boceprevir Visual impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Abasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bortezomib Abdominal distension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Abdominal pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Acidosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Acute coronary syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Acute kidney injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Acute myeloid leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Acute myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Acute pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Acute respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Agranulocytosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Ascites 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Asthenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Asthma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Atelectasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Atrial fibrillation 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Atrial flutter 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Bacteraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Bacterial infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Blepharitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bortezomib Blood creatinine increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Blood lactate dehydrogenase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Blood pressure abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Blood pressure decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Bone marrow failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bortezomib Bone pain 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Bradycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Brain oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib C-reactive protein increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Candida infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Cardiac disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Cardiac failure congestive 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Cardiogenic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Cardiotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bortezomib Cardiovascular disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Cellulitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Cerebral haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Cerebral infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Cerebrovascular accident 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Chronic kidney disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Chronic obstructive pulmonary disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Circulatory collapse 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Clostridium difficile colitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Cognitive disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bortezomib Colitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Confusional state 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Decreased appetite 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Deep vein thrombosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bortezomib Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Delirium 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bortezomib Diarrhoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Bortezomib Disease recurrence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Disseminated intravascular coagulation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Diverticulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Drug intolerance 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Bortezomib Drug resistance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bortezomib Dyspnoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Dyspnoea exertional 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Ejection fraction decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Electrolyte imbalance 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Encephalopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Enteritis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Epilepsy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Epistaxis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Facial paralysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Failure to thrive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Febrile neutropenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Fluid overload 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Fungal infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bortezomib Gastric disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Gastroenteritis viral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Gastrointestinal disorder 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Bortezomib Gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Haematemesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Haemoglobin decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Haemoptysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Haemorrhage intracranial 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Hepatic function abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Hepatotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bortezomib Herpes simplex 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Herpes zoster 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Hypercalcaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Hyperglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Hypersensitivity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bortezomib Hypoalbuminaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Hypocalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Hypoglycaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Hypotension 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Hypoxia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Ileus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Ileus paralytic 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Interstitial lung disease 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Intestinal obstruction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Ischaemic stroke 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Joint swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Laceration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Large intestine perforation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bortezomib Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Leukopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Liver disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bortezomib Liver function test abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Lung disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Lung infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Lung infiltration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Lymphadenopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Lymphopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bortezomib Malignant neoplasm progression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Malnutrition 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Mucosal inflammation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Muscular weakness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Bortezomib Musculoskeletal chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Musculoskeletal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Myelodysplastic syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Nervous system disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Nervousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Bortezomib Neurotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bortezomib Neutropenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Oesophagitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Oliguria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Osteomyelitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Oxygen saturation decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bortezomib Pain in extremity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Bortezomib Pancreatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Pancreatitis acute 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Pericardial effusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Pericarditis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Peripheral sensory neuropathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bortezomib Peritonitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Petechiae 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Plasma cell myeloma 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Bortezomib Platelet count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Pleural effusion 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Pneumonia aspiration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Polyneuropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bortezomib Posterior reversible encephalopathy syndrome 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Bortezomib Productive cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Proteinuria 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Pulmonary alveolar haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Pulmonary embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Pulmonary fibrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bortezomib Rash generalised 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bortezomib Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Renal impairment 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Respiratory disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Respiratory distress 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Respiratory tract infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Sciatica 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Skin disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bortezomib Skin infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Skin lesion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Small intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Somnolence 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Speech disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Staphylococcal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Syncope 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Tachycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Toxic epidermal necrolysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Transaminases increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bortezomib Troponin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Tumour lysis syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Upper respiratory tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Urinary tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bortezomib Urosepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Ventricular tachycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bortezomib Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Abasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Abdominal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Abdominal distension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Bosentan Acute myocardial infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Acute pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bosentan Acute respiratory failure 1.0 1.0 1.0 0.0 1.0 0.0 0.0 Bosentan Agitation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Alanine aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Alopecia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Altered state of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Amnesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Anaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Angina pectoris 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Angiopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Anuria 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Aphasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Apnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Appendicitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Arrhythmia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Arthritis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Bosentan Arthropathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Ascites 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Aspartate aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Aspiration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Asthenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Asthma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Atrial flutter 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bosentan Atrial septal defect 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Atrioventricular block 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Atrioventricular block complete 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Bacteraemia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Bosentan Bacterial infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Balance disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bosentan Blood alkaline phosphatase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Blood bilirubin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Blood count abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Blood creatine phosphokinase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Blood creatinine increased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Bosentan Blood disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Blood glucose decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Blood magnesium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Blood potassium increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Blood pressure abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Blood pressure decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Blood urea increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Bone disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Bradycardia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Brain injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Brain oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Breast cancer 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bosentan Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan C-reactive protein increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Candida infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Cardiac arrest 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Cardiac disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Cardiac failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Bosentan Cardiac failure acute 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Cardiac failure congestive 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Bosentan Cardiac murmur 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bosentan Cardiac tamponade 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bosentan Cardiogenic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bosentan Cardiomegaly 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Cardiomyopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Cardiopulmonary failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bosentan Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Cerebral haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Cerebral infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Cerebrovascular accident 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Chest discomfort 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Choking 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Cholecystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Chromaturia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Chronic kidney disease 1.0 0.0 1.0 1.0 0.0 0.0 0.0 Bosentan Chronic obstructive pulmonary disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Circulatory collapse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bosentan Clostridium difficile colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Clostridium difficile infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Coagulopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Colon cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bosentan Coma 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Confusional state 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Conjunctivitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Contusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Coronary artery disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bosentan Cough 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Crohn's disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Cyanosis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Cyst 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Cystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bosentan Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Decubitus ulcer 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Deep vein thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Dementia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bosentan Depressed level of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Depressed mood 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Depression 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bosentan Diabetes mellitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bosentan Diarrhoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Diarrhoea haemorrhagic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bosentan Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Disturbance in attention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Diverticulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Dizziness postural 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Drug hypersensitivity 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Bosentan Drug intolerance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Dry mouth 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Dry skin 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Dysgeusia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Dyskinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Dyspepsia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Dysphagia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Bosentan Dysphonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Dyspnoea exertional 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Ear infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Electrocardiogram abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Encephalopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bosentan Epilepsy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bosentan Epistaxis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Erythema 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Bosentan Eye swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Faeces discoloured 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Failure to thrive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Fatigue 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Feeding disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Feeling abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Feeling hot 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Femur fracture 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Flatulence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Fluid overload 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Bosentan Fluid retention 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Flushing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Full blood count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Fungal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Gallbladder disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Gamma-glutamyltransferase increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Gastric disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Gastric haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Gastric ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Gastritis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Gastroenteritis viral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Gastrointestinal haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Gastrooesophageal reflux disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Generalised oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Gout 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Bosentan Haematemesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Haematochezia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Bosentan Haematocrit decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Haemoglobin decreased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Bosentan Haemolytic anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Haemoptysis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Haemorrhage intracranial 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Haemorrhoids 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Heart rate decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Heart rate irregular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Hemiparesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Hepatic cancer 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Hepatic cirrhosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bosentan Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bosentan Hepatic function abnormal 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Bosentan Hepatomegaly 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Hernia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Bosentan Herpes zoster 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Hip fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Hypercalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Hyperglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bosentan Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Hyperkalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Hypersensitivity 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Bosentan Hypersomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Hypoacusis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Hypoaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Hypoglycaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bosentan Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Hypotension 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Bosentan Hypoxia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Ileus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bosentan Ill-defined disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Immune system disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Influenza like illness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Interstitial lung disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Intervertebral disc protrusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Intestinal obstruction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Irritability 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Joint swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Laceration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Lethargy 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Liver disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Liver function test abnormal 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Liver function test increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Local swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Localised infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Loss of consciousness 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Lower respiratory tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bosentan Lung disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Lung infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bosentan Lymphadenopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Lymphoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Malaise 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Malnutrition 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bosentan Melaena 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bosentan Memory impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Meningitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Menorrhagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Mental disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bosentan Mental status changes 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Metabolic acidosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bosentan Metastases to liver 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bosentan Metastases to lung 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bosentan Migraine 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Bosentan Mobility decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Movement disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Multiple fractures 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bosentan Muscle spasms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Musculoskeletal chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Musculoskeletal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Musculoskeletal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bosentan Musculoskeletal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Musculoskeletal stiffness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Myalgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Myocardial infarction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Myocardial ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Nasal congestion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Nasal dryness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Nasopharyngitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Neck pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Neoplasm malignant 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Bosentan Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Nervous system disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Nervousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Neuropathy peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Obstructive airways disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Ocular hyperaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Oedema peripheral 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Oesophagitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Oropharyngeal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Osteoarthritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Osteomyelitis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Bosentan Oxygen saturation decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Pain in jaw 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Pallor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Pancytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Panic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Paraesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Pericardial effusion 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Bosentan Peripheral swelling 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Peripheral vascular disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Peritonitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Platelet count decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Pleural effusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Pleurisy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Pneumonia aspiration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Pneumonitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Pneumothorax 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Productive cough 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Pulmonary alveolar haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bosentan Pulmonary congestion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Pulmonary embolism 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Bosentan Pulmonary fibrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bosentan Pulmonary haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Pulmonary hypertension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Pulmonary mass 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bosentan Pulmonary oedema 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Bosentan Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Rash pruritic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Raynaud's phenomenon 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Red blood cell count decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Renal disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Renal failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Renal impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bosentan Respiratory disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Respiratory distress 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Respiratory failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Bosentan Respiratory tract congestion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Respiratory tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Restless legs syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Retching 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Rheumatoid arthritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Rhinorrhoea 0.0 0.0 1.0 0.0 1.0 0.0 0.0 Bosentan Sciatica 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Seizure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Sepsis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Septic shock 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Bosentan Sinus congestion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Sinus disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Sinusitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Skin discolouration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Skin disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Skin infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Skin lesion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Skin ulcer 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Sleep apnoea syndrome 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Sleep disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Small intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Sneezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Somnolence 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Speech disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Spinal compression fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Spinal fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Splenomegaly 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bosentan Staphylococcal infection 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bosentan Stomatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Stress 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Bosentan Subdural haematoma 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bosentan Suicidal ideation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Suicide attempt 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Supraventricular tachycardia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Bosentan Swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Swelling face 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Syncope 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Systemic lupus erythematosus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bosentan Tachypnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Thirst 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Throat irritation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Throat tightness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Thrombocytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bosentan Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Tinnitus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Toothache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Transient ischaemic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Troponin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Unevaluable event 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Unresponsive to stimuli 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Upper limb fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Upper respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Urinary tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Varicose vein 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Ventricular arrhythmia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Ventricular tachycardia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Vision blurred 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Visual impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Vomiting 0.0 0.0 1.0 0.0 1.0 0.0 0.0 Bosentan Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan Weight increased 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Bosentan Wheezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan White blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosentan White blood cell count increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosutinib Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosutinib Cardiac failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosutinib Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosutinib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bosutinib Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bosutinib Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosutinib Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bosutinib Neoplasm progression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bosutinib Pancytopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bosutinib Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bosutinib monohydrate Acute kidney injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bosutinib monohydrate Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosutinib monohydrate Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosutinib monohydrate Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosutinib monohydrate Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosutinib monohydrate Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosutinib monohydrate Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosutinib monohydrate Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosutinib monohydrate Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosutinib monohydrate Fluid retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosutinib monohydrate Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosutinib monohydrate Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosutinib monohydrate Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosutinib monohydrate Neutropenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bosutinib monohydrate Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosutinib monohydrate Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosutinib monohydrate Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosutinib monohydrate Renal failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bosutinib monohydrate Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bosutinib monohydrate Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Brexpiprazole Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Brexpiprazole Blood creatine phosphokinase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Brexpiprazole Blood glucose increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brexpiprazole Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Brexpiprazole Crying 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brexpiprazole Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Brexpiprazole Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Brexpiprazole Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brexpiprazole Dysphagia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brexpiprazole Dyspnoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brexpiprazole Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Brexpiprazole Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Brexpiprazole Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Brexpiprazole Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brexpiprazole Hypertension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Brexpiprazole Mania 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Brexpiprazole Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brexpiprazole Pyrexia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Brexpiprazole Salivary hypersecretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Brexpiprazole Seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brexpiprazole Somnolence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brexpiprazole Suicidal ideation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brexpiprazole Swollen tongue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brexpiprazole Tardive dyskinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Brexpiprazole Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brigatinib Amylase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brigatinib Asthenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Brigatinib Back pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brigatinib Blood creatine phosphokinase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brigatinib Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Brigatinib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Brigatinib Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brigatinib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Brigatinib Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brigatinib Dyspnoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Brigatinib Fatigue 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Brigatinib Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brigatinib Interstitial lung disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Brigatinib Lung disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Brigatinib Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Brigatinib Malignant neoplasm progression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brigatinib Memory impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brigatinib Metastases to central nervous system 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Brigatinib Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Brigatinib Neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Brigatinib Pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Brigatinib Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Brigatinib Photosensitivity reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brigatinib Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Brigatinib Pneumonitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Brigatinib Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Brigatinib Skin exfoliation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brigatinib Sleep disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brigatinib Somnolence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brigatinib Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Brimonidine tartrate Blepharitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brimonidine tartrate Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Brimonidine tartrate Burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brimonidine tartrate Conjunctivitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brimonidine tartrate Dry eye 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brimonidine tartrate Dyspnoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brimonidine tartrate Erythema 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Brimonidine tartrate Eye irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brimonidine tartrate Eye pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brimonidine tartrate Eye pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brimonidine tartrate Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brimonidine tartrate Hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Brimonidine tartrate Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Brimonidine tartrate Hypothermia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Brimonidine tartrate Hypotonia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Brimonidine tartrate Lacrimation increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brimonidine tartrate Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Brimonidine tartrate Ocular hyperaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brimonidine tartrate Respiratory depression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Brimonidine tartrate Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Brimonidine tartrate Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brimonidine tartrate Visual acuity reduced 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Brimonidine tartrate Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brinzolamide Arrhythmia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brinzolamide Asthenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brinzolamide Blindness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brinzolamide Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brinzolamide Chest pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brinzolamide Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brinzolamide Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Brinzolamide Drug hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brinzolamide Dry eye 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brinzolamide Eye pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Brinzolamide Eye pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brinzolamide Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brinzolamide Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brinzolamide Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brinzolamide Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brinzolamide Hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brinzolamide Intraocular pressure increased 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Brinzolamide Muscle spasms 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brinzolamide Ocular hyperaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brinzolamide Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brinzolamide Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brinzolamide Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brinzolamide Visual acuity reduced 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brinzolamide Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Brivaracetam Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brivaracetam Aggression 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Brivaracetam Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brivaracetam Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Brivaracetam Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Brivaracetam Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Brivaracetam Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brivaracetam Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Brivaracetam Insomnia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Brivaracetam Intentional self-injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brivaracetam Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Brivaracetam Migraine 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brivaracetam Mood altered 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brivaracetam Mood swings 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brivaracetam Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brivaracetam Respiratory failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Brivaracetam Seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Brivaracetam Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Brivaracetam Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Brivaracetam Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bromazepam Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bromocriptine mesylate Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bromocriptine mesylate Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Budesonide Abdominal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Budesonide Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Budesonide Angioedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Budesonide Asphyxia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Budesonide Asthma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Budesonide Atrial fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Budesonide Blood pressure decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Budesonide Blood pressure increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Budesonide Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Bronchitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Budesonide Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Budesonide Candida infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Budesonide Cardiac disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Cardiac failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Budesonide Chest discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Budesonide Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Coagulopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Budesonide Colitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Budesonide Colitis ulcerative 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Budesonide Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Contusion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Budesonide Crohn's disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Budesonide Cyanosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Budesonide Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Budesonide Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Budesonide Dermatitis contact 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Budesonide Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Budesonide Diarrhoea haemorrhagic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Budesonide Disseminated intravascular coagulation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Budesonide Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Budesonide Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Budesonide Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Budesonide Dry skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Budesonide Dysphagia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Budesonide Dysphonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Budesonide Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Face oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Budesonide Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Budesonide Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Budesonide Feeling hot 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Fluid retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Budesonide Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Gastrointestinal haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Budesonide Gastrooesophageal reflux disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Budesonide Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Heart rate increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Budesonide Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Budesonide Hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Budesonide Hypoaesthesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Budesonide Hypokalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Budesonide Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Hypoxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Influenza 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Budesonide Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Budesonide Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Lacrimation increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Budesonide Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Migraine 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Budesonide Myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Budesonide Neck pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Nervousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Budesonide Oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Budesonide Oesophageal ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Oral candidiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Oxygen saturation decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Budesonide Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Pain in extremity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Budesonide Palpitations 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Budesonide Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Paraesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Prostate cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Budesonide Rales 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Budesonide Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Rash generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Rash papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Budesonide Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Sinus tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Budesonide Swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Budesonide Swelling face 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Budesonide Tinnitus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Tremor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Budesonide Ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Urticaria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Budesonide Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Budesonide Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Budesonide Weight decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Budesonide Wheezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bumetanide Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bumetanide Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bumetanide Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bumetanide Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bumetanide Cardiac failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bumetanide Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bumetanide Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bumetanide Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bumetanide Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bumetanide Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bumetanide Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bumetanide Fluid overload 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bumetanide Hyperkalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bumetanide Hypokalaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bumetanide Hypomagnesaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bumetanide Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bumetanide Hypotension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Bumetanide Hypovolaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bumetanide Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bumetanide Polyuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bumetanide Renal impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bumetanide Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bumetanide Weight increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupivacaine Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupivacaine Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupivacaine Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupivacaine Cardio-respiratory arrest 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupivacaine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bupivacaine Depressed level of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupivacaine Diplopia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupivacaine Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupivacaine Generalised tonic-clonic seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupivacaine Haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupivacaine Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupivacaine Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupivacaine Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupivacaine Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupivacaine Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupivacaine Osteoarthritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupivacaine Paraesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupivacaine Paralysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupivacaine Respiratory arrest 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupivacaine Respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupivacaine Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupivacaine Sensory loss 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupivacaine Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupivacaine Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupivacaine Tremor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupivacaine Ventricular fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupivacaine Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupivacaine hydrochloride Agitation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupivacaine hydrochloride Anal incontinence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupivacaine hydrochloride Anxiety 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupivacaine hydrochloride Back pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bupivacaine hydrochloride Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupivacaine hydrochloride Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupivacaine hydrochloride Depression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupivacaine hydrochloride Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Bupivacaine hydrochloride Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupivacaine hydrochloride Muscular weakness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bupivacaine hydrochloride Nausea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Bupivacaine hydrochloride Restlessness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Bupivacaine hydrochloride Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupivacaine hydrochloride Urinary incontinence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupivacaine hydrochloride Vomiting 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Buprenorphine Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Buprenorphine Acute kidney injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Buprenorphine Agitation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Buprenorphine Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Buprenorphine Apathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Buprenorphine Arthralgia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Buprenorphine Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Buprenorphine Back pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Buprenorphine Blister 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Buprenorphine Bone pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Buprenorphine Burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Buprenorphine Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Buprenorphine Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Buprenorphine Coma 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Buprenorphine Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Buprenorphine Confusional state 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Buprenorphine Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Buprenorphine Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Buprenorphine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Buprenorphine Delirium 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Buprenorphine Depressed level of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Buprenorphine Depression 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Buprenorphine Dermatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Buprenorphine Dermatitis allergic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Buprenorphine Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Buprenorphine Discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Buprenorphine Disorientation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Buprenorphine Disturbance in attention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Buprenorphine Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Buprenorphine Drug dependence 0.0 0.0 0.0 1.0 1.0 0.0 1.0 Buprenorphine Drug intolerance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Buprenorphine Drug withdrawal syndrome 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Buprenorphine Dysarthria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Buprenorphine Dysphagia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Buprenorphine Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Buprenorphine Dysuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Buprenorphine Emotional disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Buprenorphine Erectile dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Buprenorphine Feeling abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Buprenorphine Feeling cold 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Buprenorphine Feeling hot 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Buprenorphine Gait disturbance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Buprenorphine Hallucination 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Buprenorphine Headache 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Buprenorphine Heart rate increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Buprenorphine Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Buprenorphine Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Buprenorphine Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Buprenorphine Influenza like illness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Buprenorphine Injury 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Buprenorphine Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Buprenorphine Irritability 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Buprenorphine Lethargy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Buprenorphine Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Buprenorphine Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Buprenorphine Maternal drugs affecting foetus 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Buprenorphine Memory impairment 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Buprenorphine Mental impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Buprenorphine Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Buprenorphine Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Buprenorphine Miosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Buprenorphine Mood altered 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Buprenorphine Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Buprenorphine Muscle twitching 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Buprenorphine Myalgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Buprenorphine Mydriasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Buprenorphine Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Buprenorphine Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Buprenorphine Nervous system disorder 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Buprenorphine Nervousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Buprenorphine Pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Buprenorphine Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Buprenorphine Pallor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Buprenorphine Paranoia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Buprenorphine Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Buprenorphine Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Buprenorphine Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Buprenorphine Psychomotor hyperactivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Buprenorphine Psychotic disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Buprenorphine Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Buprenorphine Rash 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Buprenorphine Rash pruritic 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Buprenorphine Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Buprenorphine Respiratory depression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Buprenorphine Respiratory disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Buprenorphine Respiratory distress 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Buprenorphine Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Buprenorphine Sedation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Buprenorphine Skin irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Buprenorphine Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Buprenorphine Staphylococcal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Buprenorphine Suicidal ideation 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Buprenorphine Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Buprenorphine Swelling face 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Buprenorphine Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Buprenorphine Tachycardia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Buprenorphine Tinnitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Buprenorphine Unevaluable event 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Buprenorphine Unresponsive to stimuli 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Buprenorphine Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Buprenorphine Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Buprenorphine Visual impairment 0.0 0.0 0.0 0.0 1.0 0.0 1.0 Buprenorphine Vomiting 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Buprenorphine Withdrawal syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Buprenorphine hydrochloride Abscess 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Buprenorphine hydrochloride Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Buprenorphine hydrochloride Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Buprenorphine hydrochloride Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupropion Abdominal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion Abdominal pain upper 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bupropion Acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Acute generalised exanthematous pustulosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bupropion Acute kidney injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Agitation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Agranulocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bupropion Altered state of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupropion Amnesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Anger 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bupropion Angioedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupropion Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Bupropion Aphasia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Apnoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bupropion Arrhythmia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion Asthma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupropion Atrial septal defect 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Bupropion Blood creatinine increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion Bradycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Brain injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Brain oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bupropion Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bupropion Cardiac arrest 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Bupropion Cardiac disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupropion Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bupropion Cardiogenic shock 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bupropion Cardiomyopathy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bupropion Cardiotoxicity 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Carpal tunnel syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupropion Cerebral infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Cerebrovascular accident 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Chest discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Circulatory collapse 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bupropion Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupropion Congestive cardiomyopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bupropion Constipation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bupropion Crying 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Bupropion Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bupropion Delirium 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Delusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupropion Depressed level of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Depression 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Bupropion Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion Disease recurrence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bupropion Disorientation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bupropion Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bupropion Dyskinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupropion Eczema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupropion Ejection fraction decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Electrocardiogram QT prolonged 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Bupropion Encephalopathy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bupropion Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Bupropion Flank pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion Fluid retention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bupropion Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bupropion Gastrooesophageal reflux disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupropion Generalised tonic-clonic seizure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bupropion Haemoglobin decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion Hallucination 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Hallucination, visual 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Bupropion Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Hyperreflexia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Hypertension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion Hyperthermia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupropion Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Hypoxia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bupropion Infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion Intentional self-injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bupropion Irritability 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Bupropion Lactic acidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bupropion Lethargy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Leukocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Leukopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupropion Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Malaise 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bupropion Maternal drugs affecting foetus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion Mental status changes 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bupropion Metabolic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion Mood altered 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bupropion Muscle rigidity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupropion Mydriasis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bupropion Myocardial infarction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bupropion Myocardial ischaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bupropion Myoclonus 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Bupropion Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion Nervous system disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupropion Neurotoxicity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bupropion Nystagmus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupropion Oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bupropion Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion Pneumonia aspiration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Bupropion Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bupropion Psoriasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bupropion Psychomotor hyperactivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupropion Psychotic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupropion Pulmonary congestion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bupropion Pulmonary haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupropion Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bupropion Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bupropion Respiratory depression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Rhabdomyolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Seizure 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Bupropion Serotonin syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bupropion Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Sinus bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupropion Sinus tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bupropion Somnolence 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Bupropion Status epilepticus 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Bupropion Stevens-Johnson syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupropion Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Suicide attempt 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bupropion Supraventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bupropion Tachypnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupropion Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion Torsade de pointes 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Transaminases increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupropion Transient ischaemic attack 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Tremor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Unresponsive to stimuli 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bupropion Ventricular arrhythmia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Ventricular extrasystoles 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion Ventricular fibrillation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bupropion Ventricular tachycardia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Bupropion Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bupropion Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupropion Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion hydrochloride Abdominal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bupropion hydrochloride Aggression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion hydrochloride Agitation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion hydrochloride Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion hydrochloride Amnesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion hydrochloride Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bupropion hydrochloride Aphasia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion hydrochloride Arrhythmia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion hydrochloride Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion hydrochloride Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion hydrochloride Bronchitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bupropion hydrochloride Cerebrovascular accident 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion hydrochloride Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion hydrochloride Chills 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bupropion hydrochloride Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion hydrochloride Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Bupropion hydrochloride Confusional state 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion hydrochloride Constipation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bupropion hydrochloride Cystitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bupropion hydrochloride Deafness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion hydrochloride Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Bupropion hydrochloride Depression 0.0 1.0 0.0 1.0 0.0 1.0 1.0 Bupropion hydrochloride Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion hydrochloride Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion hydrochloride Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion hydrochloride Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion hydrochloride Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bupropion hydrochloride Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupropion hydrochloride Euphoric mood 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bupropion hydrochloride Haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bupropion hydrochloride Hallucination 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion hydrochloride Headache 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Bupropion hydrochloride Hyperhidrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bupropion hydrochloride Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bupropion hydrochloride Hypoaesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bupropion hydrochloride Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion hydrochloride Infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion hydrochloride Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bupropion hydrochloride Irritability 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Bupropion hydrochloride Lymphadenopathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bupropion hydrochloride Malaise 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Bupropion hydrochloride Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Bupropion hydrochloride Mental disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupropion hydrochloride Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion hydrochloride Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion hydrochloride Mydriasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupropion hydrochloride Myoclonus 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bupropion hydrochloride Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion hydrochloride Pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bupropion hydrochloride Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion hydrochloride Palpitations 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Bupropion hydrochloride Pollakiuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bupropion hydrochloride Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion hydrochloride Pyrexia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion hydrochloride Rhabdomyolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion hydrochloride Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion hydrochloride Sleep disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion hydrochloride Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion hydrochloride Suicidal ideation 0.0 1.0 0.0 0.0 0.0 1.0 1.0 Bupropion hydrochloride Suicide attempt 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Bupropion hydrochloride Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Bupropion hydrochloride Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion hydrochloride Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion hydrochloride Upper respiratory tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Bupropion hydrochloride Urticaria 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Bupropion hydrochloride Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Bupropion hydrochloride Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion hydrochloride Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Bupropion hydrochloride Weight decreased 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Bupropion hydrochloride Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Buspirone hydrochloride Akathisia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Buspirone hydrochloride Anger 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Buspirone hydrochloride Confusional state 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Buspirone hydrochloride Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Buspirone hydrochloride Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Buspirone hydrochloride Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Buspirone hydrochloride Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Buspirone hydrochloride Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Buspirone hydrochloride Muscle rigidity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Buspirone hydrochloride Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Buspirone hydrochloride Serotonin syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Buspirone hydrochloride Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Buspirone hydrochloride Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Buspirone hydrochloride Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Busulfan Acute kidney injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Busulfan Acute myeloid leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Busulfan Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Busulfan Aplastic anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Busulfan Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Busulfan Bacteraemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Busulfan Blood bilirubin increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Busulfan Bone marrow failure 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Busulfan Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Busulfan Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Busulfan Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Busulfan Confusional state 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Busulfan Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Busulfan Diarrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Busulfan Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Busulfan Disease recurrence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Busulfan Drug interaction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Busulfan Dyspnoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Busulfan Epistaxis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Busulfan Erythema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Busulfan Febrile neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Busulfan Fungal infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Busulfan Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Busulfan Generalised oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Busulfan Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Busulfan Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Busulfan Haemorrhage intracranial 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Busulfan Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Busulfan Hepatic necrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Busulfan Hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Busulfan Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Busulfan Hypoxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Busulfan Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Busulfan Interstitial lung disease 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Busulfan Lung disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Busulfan Malaise 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Busulfan Mucosal inflammation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Busulfan Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Busulfan Nephropathy toxic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Busulfan Neutropenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Busulfan Obstructive airways disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Busulfan Oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Busulfan Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Busulfan Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Busulfan Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Busulfan Pulmonary alveolar haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Busulfan Pulmonary hypertension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Busulfan Pulmonary oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Busulfan Pyrexia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Busulfan Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Busulfan Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Busulfan Renal impairment 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Busulfan Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Busulfan Seizure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Busulfan Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Busulfan Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Busulfan Shock haemorrhagic 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Busulfan Staphylococcal infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Busulfan Stomatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Busulfan Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Busulfan Vomiting 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cabazitaxel Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabazitaxel Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabazitaxel Anaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cabazitaxel Asthenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cabazitaxel Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabazitaxel Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cabazitaxel Confusional state 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cabazitaxel Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabazitaxel Cough 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cabazitaxel Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cabazitaxel Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cabazitaxel Deep vein thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabazitaxel Dehydration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabazitaxel Diarrhoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cabazitaxel Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cabazitaxel Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabazitaxel Dyspnoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cabazitaxel Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabazitaxel Enterocolitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabazitaxel Fatigue 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabazitaxel Febrile neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cabazitaxel Haematuria 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabazitaxel Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabazitaxel Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabazitaxel Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cabazitaxel Lacrimation increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabazitaxel Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabazitaxel Leukopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabazitaxel Malaise 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cabazitaxel Neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cabazitaxel Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabazitaxel Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabazitaxel Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cabazitaxel Pyrexia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cabazitaxel Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabazitaxel Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cabazitaxel Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cabazitaxel Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cabazitaxel Tachycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cabazitaxel Thrombocytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cabazitaxel Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabazitaxel Urinary tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabazitaxel Vomiting 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabazitaxel Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabergoline Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cabergoline Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cabergoline Asthenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cabergoline Blindness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cabergoline Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cabergoline Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cabergoline Drug resistance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cabergoline Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cabergoline Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabergoline Irritability 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabergoline Mania 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabergoline Neoplasm progression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cabergoline Posterior reversible encephalopathy syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabergoline Psychotic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabergoline Pulmonary fibrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cabergoline Somnolence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cabergoline Syncope 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cabergoline Weight decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cabozantinib Abdominal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Abdominal distension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cabozantinib Abdominal pain 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Abscess 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Acute myocardial infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Acute respiratory failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Ageusia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Alanine aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Alopecia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Anaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Anxiety 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Aphasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Arthralgia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Ascites 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Aspartate aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Asthenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Ataxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Atrial fibrillation 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Back pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Blister 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Blood alkaline phosphatase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cabozantinib Blood bilirubin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Blood lactate dehydrogenase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Bone pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib C-reactive protein increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cabozantinib Cardiac failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Cerebrovascular accident 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Chest pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Cholecystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Cholecystitis acute 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Cholestasis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Chronic kidney disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Cognitive disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Confusional state 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Constipation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Death 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cabozantinib Decreased appetite 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Decubitus ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Deep vein thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Dehydration 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Diarrhoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Diplopia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Disease progression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cabozantinib Diverticulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Dizziness 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Dry mouth 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Dry skin 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Dysgeusia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Dyspepsia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Dysphagia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Dysphonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Dyspnoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Ear pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Ejection fraction decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Embolism 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Encephalopathy 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Enteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Epistaxis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Erythema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Face oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Failure to thrive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Fatigue 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Flank pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Gamma-glutamyltransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cabozantinib Gastric haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Gastrointestinal haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Gastrooesophageal reflux disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Glossitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cabozantinib Gout 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Haemoptysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Haemorrhage intracranial 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Haemorrhoids 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Headache 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Hepatic encephalopathy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cabozantinib Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Hepatotoxicity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Hyperbilirubinaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Hypercalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Hyperkalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Hypertension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Hyperthyroidism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Hypoaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Hypoalbuminaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cabozantinib Hypocalcaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Hypoglycaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Hypomagnesaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Hyponatraemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Hypothyroidism 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Hypoxia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cabozantinib Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Insomnia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Intestinal obstruction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Intestinal perforation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cabozantinib Large intestine perforation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cabozantinib Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Liver function test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Lower respiratory tract infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cabozantinib Lymphadenopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cabozantinib Lymphocyte count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Malignant neoplasm progression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cabozantinib Memory impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Mental status changes 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Metastases to central nervous system 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Mucosal inflammation 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Cabozantinib Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cabozantinib Muscle spasms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Musculoskeletal chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Musculoskeletal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Myalgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Myocardial infarction 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Nausea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Neck pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Night sweats 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Oesophagitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Oral candidiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Oral pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cabozantinib Pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Pain in extremity 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Pancytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Paraesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Pericardial effusion 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cabozantinib Platelet count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Pleural effusion 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Pneumonia aspiration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Pneumonitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Pneumothorax 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Posterior reversible encephalopathy syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cabozantinib Proctalgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Proteinuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Pulmonary embolism 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Pyrexia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Renal failure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Renal impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cabozantinib Rhinorrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Sepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cabozantinib Skin disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Skin exfoliation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Skin infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Skin ulcer 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cabozantinib Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Stomatitis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Tachycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cabozantinib Thrombocytopenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Transaminases increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Transient ischaemic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Urinary tract infection 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Vasculitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cabozantinib Vomiting 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib Weight decreased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib White blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Abdominal pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Abdominal pain upper 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Alanine aminotransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Alopecia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Aspartate aminotransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Asthenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Blood pressure increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Constipation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Decreased appetite 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Dehydration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Diarrhoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Dizziness 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Dry skin 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Dysgeusia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Dyspepsia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Dysphagia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Dysphonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Erythema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Fatigue 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Glossodynia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Haemorrhoids 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Headache 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Hyperbilirubinaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Hypertension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Hypocalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Hypokalaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Hypomagnesaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Hyponatraemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Hypotension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Mouth ulceration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Mucosal inflammation 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Cabozantinib s-malate Muscle spasms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Musculoskeletal chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Nausea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Neuropathy peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Neutropenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Oral pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Oropharyngeal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Paraesthesia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Posterior reversible encephalopathy syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Proteinuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cabozantinib s-malate Rash 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Stomatitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Thrombocytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Vomiting 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cabozantinib s-malate Weight decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Caffeine Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Caffeine Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Calcitriol Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Calcitriol Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Calcitriol Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Calcitriol Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Calcitriol Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Calcitriol Blood urea increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Calcitriol Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Calcitriol Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Calcitriol Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Calcitriol Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Calcitriol Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Calcitriol Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Calcitriol Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Calcitriol Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Calcitriol Hypercalcaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Calcitriol Hyperkalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Calcitriol Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Calcitriol Hypocalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Calcitriol Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Calcitriol Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Calcitriol Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Calcitriol Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Calcitriol Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Calcitriol Peritonitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Calcitriol Polyuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Calcitriol Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Calcitriol Seizure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Calcitriol Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Calcitriol Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Calcitriol Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Calcium acetate Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Calcium acetate Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Abdominal distension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Canagliflozin Abdominal pain 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Canagliflozin Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Acidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Acute kidney injury 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Canagliflozin Acute myocardial infarction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Angioedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Canagliflozin Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Canagliflozin Asthenia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Canagliflozin Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Back pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Canagliflozin Bacteraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Blood cholesterol increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Canagliflozin Blood creatinine increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Canagliflozin Blood glucose decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Canagliflozin Blood glucose increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Blood potassium increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Canagliflozin Blood pressure decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Canagliflozin Burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Canagliflozin Candida infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Canagliflozin Cardiac disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Canagliflozin Cardiac failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Cardiac failure congestive 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Cellulitis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Canagliflozin Cerebral infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Cerebrovascular accident 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Cholecystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Cholecystitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Chronic kidney disease 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Canagliflozin Chronic obstructive pulmonary disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Circulatory collapse 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Colon cancer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Coma 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Confusional state 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Contusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Canagliflozin Decreased appetite 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Canagliflozin Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Depression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Diabetic ketoacidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Diarrhoea 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Canagliflozin Dizziness postural 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Canagliflozin Drug intolerance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Canagliflozin Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Canagliflozin Dysuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Canagliflozin Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Facial paralysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Canagliflozin Femur fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Fungal infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Canagliflozin Gait disturbance 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Canagliflozin Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Gastroenteritis viral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Glycosuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Haematemesis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Canagliflozin Headache 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Canagliflozin Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Canagliflozin Hyperglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Hyperkalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Hypernatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Canagliflozin Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Canagliflozin Hypoaesthesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Canagliflozin Hypoglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Infection 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Canagliflozin Inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Influenza like illness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Iron deficiency anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Ischaemic stroke 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Lactic acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Lethargy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Leukocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Lip swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Canagliflozin Lipase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Liver disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Localised infection 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Canagliflozin Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Canagliflozin Malaise 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Mental impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Canagliflozin Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Metabolic acidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Canagliflozin Myocardial infarction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Nausea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Necrosis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Canagliflozin Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Canagliflozin Osteomyelitis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Canagliflozin Pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Canagliflozin Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Canagliflozin Pancreatic carcinoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Canagliflozin Pancreatitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Pancreatitis acute 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Pelvic pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Peripheral ischaemia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Canagliflozin Peripheral vascular disorder 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Canagliflozin Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Polyuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Canagliflozin Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Canagliflozin Pulmonary embolism 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Pyelonephritis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Canagliflozin Renal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Canagliflozin Renal failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Canagliflozin Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Canagliflozin Renal tubular necrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Respiratory failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Sepsis 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Canagliflozin Septic shock 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Canagliflozin Shock 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Skin ulcer 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Canagliflozin Somnolence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Canagliflozin Staphylococcal infection 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Canagliflozin Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Canagliflozin Suicidal ideation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Canagliflozin Swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Canagliflozin Swelling face 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Canagliflozin Swollen tongue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Canagliflozin Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Canagliflozin Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Thirst 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Canagliflozin Thrombocytopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Transient ischaemic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Ulcer 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Canagliflozin Unevaluable event 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Urinary tract disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Urosepsis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Canagliflozin Vaginal discharge 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Canagliflozin Weight decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Canagliflozin White blood cell count increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Candesartan Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan Cardiac failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan Diarrhoea 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Candesartan Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Candesartan Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan Hyperkalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Candesartan Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Candesartan Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan Renal impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Candesartan Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Abdominal distension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Candesartan cilexetil Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Angina pectoris 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Atrial septal defect 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Candesartan cilexetil Blood creatine phosphokinase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Blood pressure fluctuation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Candesartan cilexetil Blood pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Candesartan cilexetil Bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Cardiac failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Chronic kidney disease 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Cystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Diarrhoea 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Candesartan cilexetil Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Candesartan cilexetil Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Candesartan cilexetil Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Dyspnoea exertional 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Gastrooesophageal reflux disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Haematochezia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Hyperkalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Candesartan cilexetil Hypoglycaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Liver function test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Malnutrition 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Metabolic acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Candesartan cilexetil Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Pancytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Pneumonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Polyuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Pulmonary embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Renal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Renal failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Renal impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Shock 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Toxic skin eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Transaminases increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Candesartan cilexetil Weight increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cangrelor Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cangrelor Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cannabidiol Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Aspiration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Balance disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cannabidiol Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Crying 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cannabidiol Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cannabidiol Drug hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Dystonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Epilepsy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Feeling abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cannabidiol Femur fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Gastrooesophageal reflux disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Hypersomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Liver function test increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cannabidiol Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Pneumonia aspiration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Respiratory disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Respiratory distress 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Restlessness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Salivary hypersecretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Sepsis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Sleep disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Status epilepticus 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cannabidiol Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cannabidiol Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Abdominal distension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Abdominal pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Abdominal pain lower 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Abscess 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Acidosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Acne 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Acute coronary syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Acute hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Acute myeloid leukaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Acute myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Acute respiratory failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Agranulocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Alanine aminotransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Altered state of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Anaemia 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Anal incontinence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Angioedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Anuria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Aphasia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Arrhythmia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Aspartate aminotransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Asthenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Ataxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Atrial fibrillation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Back pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Bacteraemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Bacterial infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Balance disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Blood creatine phosphokinase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Blood creatinine increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Blood disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Blood glucose increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Blood lactate dehydrogenase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Blood magnesium decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Blood pressure decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Blood urea increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Bone marrow failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Bone pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Brain injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Breast cancer 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Bronchitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine C-reactive protein increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Cachexia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Candida infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Cardiac disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Cardiac failure acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Cardiac failure congestive 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Cardiogenic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Cardiomyopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Cerebral ischaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Cerebrovascular accident 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Chest discomfort 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Chest pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Chills 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Cholelithiasis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Circulatory collapse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Clostridium difficile colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Clostridium difficile infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Coagulopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Colitis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Colitis ulcerative 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Colon cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Confusional state 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Constipation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Contusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Coordination abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Cough 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Decubitus ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Deep vein thrombosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Dehydration 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Depressed level of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Dermatitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Diabetic ketoacidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Diarrhoea 1.0 1.0 1.0 0.0 0.0 1.0 0.0 Capecitabine Diarrhoea haemorrhagic 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Disease recurrence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Disseminated intravascular coagulation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Drug hypersensitivity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Drug intolerance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Dry skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Dysaesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Dyskinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Dysphagia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Dysphonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Dyspnoea exertional 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Electrolyte imbalance 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Embolism 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Encephalopathy 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Enteritis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Enterocolitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Epilepsy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Erythema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Eye pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Faeces discoloured 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Fatigue 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Febrile neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Feeding disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Feeling abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Feeling hot 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Femur fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Fluid retention 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Frequent bowel movements 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Full blood count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Fungal infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Capecitabine Gamma-glutamyltransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Gastric cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Gastric disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Gastric haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Gastritis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Gastroenteritis 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Capecitabine Gastroenteritis viral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Gastrointestinal disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Generalised oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Gingival bleeding 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Granulocytopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Haematemesis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Haematochezia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Haemodynamic instability 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Haemolytic anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Haemoptysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Haemorrhoids 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Hepatic cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Hepatic cirrhosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Hepatic function abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Hepatic necrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Hepatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Hepatotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Hiccups 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Hip fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Hot flush 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Hyperaesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Hyperhidrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Hypertensive crisis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Hypoacusis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Hypoaesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Hypoalbuminaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Hypoglycaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Hypokalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Hypomagnesaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Hypophagia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Hypophosphataemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Hypotension 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Hypothermia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Hypoxia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Ileus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Ileus paralytic 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Immune system disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Incontinence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Inflammation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Injection site pain 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Interstitial lung disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Intestinal obstruction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Intestinal perforation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Ischaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Ischaemic stroke 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Jaundice 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Lacrimation increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Large intestine perforation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Left ventricular dysfunction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Lethargy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Leukocytosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Leukopenia 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Lip swelling 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Liver function test abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Liver injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Lower respiratory tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Lymphadenopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Lymphocyte count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Lymphoedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Lymphopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Malaise 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Malnutrition 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Mass 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Melaena 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Memory impairment 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Capecitabine Mental status changes 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Metabolic acidosis 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Capecitabine Metastases to central nervous system 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Metastases to liver 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Metastases to lung 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Metastatic neoplasm 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Migraine 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Mitral valve incompetence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Mobility decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Mood altered 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Mouth ulceration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Movement disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Mucosal inflammation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Musculoskeletal pain 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Myelodysplastic syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Myocardial ischaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Nail disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Nausea 1.0 0.0 0.0 0.0 0.0 1.0 0.0 Capecitabine Neoplasm 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Nephropathy toxic 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Nervous system disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Neurotoxicity 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Neutrophil count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Night sweats 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Ocular hyperaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Oesophagitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Oral candidiasis 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Capecitabine Oral pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Orthostatic hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Oxygen saturation decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Pain in extremity 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Capecitabine Pain in jaw 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Capecitabine Palpitations 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Pancreatic carcinoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Pancreatitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Paraesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Pericardial effusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Peripheral coldness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Peripheral sensory neuropathy 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Capecitabine Peritonitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Petechiae 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Pharyngeal oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Photophobia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Pigmentation disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Platelet count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Pleural effusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Pneumonia aspiration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Pneumonitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Pneumothorax 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Pollakiuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Polyneuropathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Posterior reversible encephalopathy syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Proctalgia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Productive cough 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Proteinuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Pulmonary embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Pulmonary fibrosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Pulmonary mass 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Pulmonary oedema 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Pyrexia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Rales 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Rash erythematous 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Rash macular 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Rash pruritic 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Rectal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Rectal tenesmus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Renal impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Respiratory distress 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Retinal detachment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Sensory disturbance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Shock haemorrhagic 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Sinusitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Skin burning sensation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Skin lesion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Skin reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Sleep disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Small intestinal obstruction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Somnolence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Speech disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Staphylococcal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Stevens-Johnson syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Stomatitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Stress cardiomyopathy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Swelling face 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Swollen tongue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Syncope 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Tachycardia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Tachypnoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Tenderness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Throat irritation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Throat tightness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Tinnitus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Tongue discolouration 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Tooth disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Toxic epidermal necrolysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Transaminases increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Treatment failure 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Ulcer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Unevaluable event 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Upper gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Upper respiratory tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Urinary incontinence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Urinary tract disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Urinary tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Vaginal haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Ventricular fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Ventricular tachycardia 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Capecitabine Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine Visual acuity reduced 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capecitabine Vomiting 1.0 1.0 0.0 0.0 0.0 1.0 0.0 Capecitabine Weight decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capecitabine Wheezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Capecitabine White blood cell count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Capsaicin Burning sensation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Capsaicin Cough 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Capsaicin Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Capsaicin Throat irritation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Captopril Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Captopril Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Captopril Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Captopril Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Captopril Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Captopril Diarrhoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Captopril Drug reaction with eosinophilia and systemic symptoms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Captopril Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Captopril Eosinophilia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Captopril Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Captopril Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Captopril Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Captopril Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Captopril Respiratory distress 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Captopril Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Captopril Toxic epidermal necrolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Captopril Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Captopril Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Abdominal pain upper 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carbamazepine Acne 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carbamazepine Acute hepatic failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Acute respiratory failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Affect lability 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carbamazepine Aggression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Carbamazepine Agitation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Agranulocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Alanine aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Altered state of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Anxiety 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Carbamazepine Arrhythmia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Arthralgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Carbamazepine Aspartate aminotransferase increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Asphyxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Asthma 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Carbamazepine Ataxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Atrial septal defect 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Carbamazepine Atrioventricular block 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Atrioventricular block complete 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Atrioventricular block second degree 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Balance disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Carbamazepine Blister 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Blood alkaline phosphatase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Blood bilirubin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Blood creatine phosphokinase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Blood glucose decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Blood lactate dehydrogenase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Body temperature decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Body temperature increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Brain injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Brain oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine C-reactive protein increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Cardiac disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Cardiac murmur 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Carbamazepine Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Cerebral haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Cerebral infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Cerebrovascular accident 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Carbamazepine Cheilitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Chills 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Circulatory collapse 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Coagulopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Cognitive disorder 0.0 0.0 1.0 0.0 1.0 0.0 0.0 Carbamazepine Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Coma 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Confusional state 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Carbamazepine Conjunctival hyperaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Conjunctivitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Coordination abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Cough 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carbamazepine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Depressed level of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Carbamazepine Dermatitis allergic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Dermatitis bullous 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Dermatitis exfoliative 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Diabetic ketoacidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Carbamazepine Diplopia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Carbamazepine Disorientation 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Carbamazepine Disturbance in attention 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Carbamazepine Dizziness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Drug abuse 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Drug dependence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Drug eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Drug interaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Drug intolerance 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Dry mouth 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Dry skin 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Carbamazepine Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Dysphagia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Carbamazepine Dyspnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Dysstasia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Dystonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Ear pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Electrocardiogram QT prolonged 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Electrolyte imbalance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Emotional distress 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carbamazepine Encephalopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Epilepsy 0.0 0.0 0.0 0.0 1.0 0.0 1.0 Carbamazepine Epistaxis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Erythema 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Erythema multiforme 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Eye swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Eyelid oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Face oedema 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Facial paralysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Carbamazepine Fear 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Feeding disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carbamazepine Feeling abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Femur fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Fluid retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Gastrointestinal disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Gastrooesophageal reflux disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carbamazepine Generalised oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Generalised tonic-clonic seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carbamazepine Glossodynia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Haematemesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Haematochezia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carbamazepine Haemodynamic instability 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Haemoglobin decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Headache 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Heart rate increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Hemiparesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Hepatic encephalopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Hepatic enzyme increased 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Carbamazepine Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Hepatic function abnormal 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Hepatitis cholestatic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Hepatotoxicity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Hydronephrosis 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Carbamazepine Hyperglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Hyperpyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Hyperthermia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Hypoacusis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Carbamazepine Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Carbamazepine Hypocalcaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Hyporeflexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Hypothermia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Hypoxia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Ileus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Inappropriate antidiuretic hormone secretion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Incontinence 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Carbamazepine Insomnia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Interstitial lung disease 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Ischaemic stroke 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Jaundice cholestatic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Lacrimation increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Lactic acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Lethargy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Leukocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Lip swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Liver disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Liver function test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Liver injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Loss of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Lower respiratory tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carbamazepine Lung infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Lung infiltration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Lymphadenopathy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Lymphopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Maternal drugs affecting foetus 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Carbamazepine Memory impairment 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Carbamazepine Mental impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Carbamazepine Mental status changes 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Metabolic acidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Mobility decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Motor dysfunction 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Carbamazepine Mouth ulceration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Muscle spasms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Carbamazepine Musculoskeletal stiffness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Carbamazepine Mydriasis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Myocarditis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Myoclonus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Nasopharyngitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Nausea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Neck pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carbamazepine Nervous system disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Nervousness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Carbamazepine Neuralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Neuroleptic malignant syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Night sweats 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Nystagmus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Ocular hyperaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Oedema peripheral 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Oliguria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Oral disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Oropharyngeal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Osteoarthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carbamazepine Osteoporosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carbamazepine Oxygen saturation decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Pain in extremity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Pain in jaw 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Pancytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Pericardial effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Peripheral coldness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Peripheral swelling 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Petechiae 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Pharyngeal oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carbamazepine Photophobia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Photosensitivity reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carbamazepine Platelet count decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Pleurisy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Pneumocystis jirovecii pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Pneumonia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Pneumonia aspiration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Poor quality sleep 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Carbamazepine Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Carbamazepine Premature delivery 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carbamazepine Productive cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Pruritus 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Pruritus generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Psychomotor hyperactivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Psychotic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Pulmonary embolism 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Rash 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Rash erythematous 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Rash generalised 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Rash macular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Rash maculo-papular 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Rash papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Rash pruritic 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Renal failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Renal impairment 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Carbamazepine Respiratory depression 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Respiratory disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Respiratory distress 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Respiratory failure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Rhabdomyolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Scab 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Sedation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Seizure 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Carbamazepine Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Septic shock 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Serotonin syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Sinus tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Skin burning sensation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Skin disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Skin exfoliation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Carbamazepine Skin hyperpigmentation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Skin infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Skin lesion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Somnolence 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Sopor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Speech disorder 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Carbamazepine Staphylococcal infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Status epilepticus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Stevens-Johnson syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Stress cardiomyopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Stupor 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Swelling face 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Syncope 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Thirst 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Thrombocytopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Toxic epidermal necrolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Toxic skin eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Transaminases increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Unresponsive to stimuli 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Urine output decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine Ventricular fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Carbamazepine Visual acuity reduced 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carbamazepine Visual impairment 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Carbamazepine Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carbamazepine Weight increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carbamazepine White blood cell count increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Abdominal discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Abdominal distension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Abdominal pain lower 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Abdominal pain upper 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Acute coronary syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Acute hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Acute myeloid leukaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Acute myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Acute respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Aggression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Agranulocytosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Alanine aminotransferase increased 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Carboplatin Alopecia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Altered state of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Anaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Carboplatin Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Angina pectoris 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Anuria 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Anxiety 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Aphthous ulcer 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Carboplatin Ascites 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Asphyxia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Asthenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Ataxia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Carboplatin Atelectasis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Atrial fibrillation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Atrial flutter 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Bacteraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Blindness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Carboplatin Blister 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Blood alkaline phosphatase increased 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Carboplatin Blood bilirubin increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Blood magnesium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Blood pressure decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Blood pressure increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Blood sodium decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Blood urea increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Body temperature increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Bone marrow failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Bradycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Brain oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Cachexia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Candida infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Cardiac disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Cardiac failure acute 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Cardiac failure congestive 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Cardiac tamponade 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Cardiogenic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Cardiotoxicity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Cellulitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Cerebral haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Cerebral infarction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Cerebrovascular accident 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Chest discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Chest pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Chills 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Cholestasis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Chromaturia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Chronic kidney disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Chronic obstructive pulmonary disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Circulatory collapse 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Clostridium difficile colitis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Clostridium difficile infection 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Cognitive disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Carboplatin Cold sweat 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Colitis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Colitis ischaemic 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Confusional state 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Congestive cardiomyopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Cough 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Carboplatin Cyanosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Cystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Deafness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Carboplatin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Decreased appetite 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Dehydration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Dementia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Depressed level of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Depression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Dermatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carboplatin Dermatitis exfoliative 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Diarrhoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Diarrhoea haemorrhagic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Diplopia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Carboplatin Disease recurrence 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Carboplatin Disorientation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Disseminated intravascular coagulation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Disturbance in attention 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Dizziness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Drug eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Drug hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Drug interaction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Drug intolerance 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Drug resistance 1.0 0.0 0.0 0.0 1.0 0.0 1.0 Carboplatin Drug-induced liver injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Dysarthria 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Dysphagia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Dyspnoea 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Carboplatin Dyspnoea exertional 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Eating disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Electrocardiogram QT prolonged 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Electrolyte imbalance 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Embolism venous 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Encephalitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Encephalopathy 1.0 1.0 1.0 1.0 0.0 0.0 0.0 Carboplatin Enteritis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Enterocolitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Epilepsy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Epistaxis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Erythema 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Carboplatin Eye pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Eye swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Face oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Faecaloma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Failure to thrive 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Febrile neutropenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Feeling abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Feeling hot 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Flank pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Flushing 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Carboplatin Frequent bowel movements 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Gait disturbance 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Gastric ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Gastrointestinal disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Generalised oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Generalised tonic-clonic seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Haematemesis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Haematochezia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Haematocrit decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Haematoma 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Carboplatin Haematuria 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Haemoglobin decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Haemolysis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carboplatin Haemolytic anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Haemoptysis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Haemorrhoids 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Heart rate increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Hepatomegaly 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Hepatotoxicity 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Carboplatin Hydronephrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Hyperbilirubinaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Hyperglycaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Hyperkalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Hyperpyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Hypertension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Hypertensive crisis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Hyperthermia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Hyperthyroidism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carboplatin Hyperuricaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Hypoaesthesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Hypocalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Hypoglycaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Hypomagnesaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Hypophagia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Hypophosphataemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Hypovolaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Hypoxia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Ileus 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Immune thrombocytopenic purpura 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Inflammation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Carboplatin Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Interstitial lung disease 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Intestinal obstruction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Intestinal perforation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Ischaemic stroke 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Carboplatin Jaundice 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Laboratory test abnormal 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Carboplatin Lacrimation increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Lactic acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Large intestine perforation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Laryngeal oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carboplatin Left ventricular dysfunction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Lethargy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Leukocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Leukopenia 1.0 1.0 1.0 0.0 1.0 0.0 0.0 Carboplatin Limb discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Liver disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Carboplatin Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Lower respiratory tract infection 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Lung disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Lung infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Lung infiltration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Lymphadenopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Lymphocyte count decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Malaise 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Carboplatin Malnutrition 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Mental status changes 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Metabolic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Metastases to central nervous system 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Metastases to liver 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Metastases to lung 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Carboplatin Metastatic neoplasm 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Motor dysfunction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Mouth ulceration 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Mucosal inflammation 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Muscle spasms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Muscular weakness 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Musculoskeletal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Myalgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Carboplatin Myelodysplastic syndrome 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Carboplatin Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Myositis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Nausea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Neoplasm 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Neoplasm progression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Nephritis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Nephropathy toxic 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Nervous system disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Neuralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Carboplatin Neurological symptom 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Neuropathy peripheral 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Carboplatin Neurotoxicity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Neutrophil count decreased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Oedema peripheral 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Oesophagitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Oral candidiasis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Oral pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Oropharyngeal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Osteonecrosis of jaw 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carboplatin Oxygen saturation decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Pallor 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Pancytopenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Paraesthesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Pelvic pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Pericarditis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Peripheral ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Peritonitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Pharyngeal oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Photosensitivity reaction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Platelet count decreased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Pleural effusion 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Pneumonia aspiration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Pneumonitis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Pneumothorax 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Posterior reversible encephalopathy syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Premature baby 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carboplatin Premature delivery 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carboplatin Presyncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Proctalgia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Productive cough 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Pruritus 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Carboplatin Pulmonary embolism 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Pulmonary fibrosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Pulmonary haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Pulmonary hypertension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Pulmonary mass 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Purpura 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Rales 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Rash erythematous 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Rash macular 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Rash pruritic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Rash vesicular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Renal impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Respiratory disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Respiratory distress 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Respiratory tract infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Restlessness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Retinal haemorrhage 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Carboplatin Seizure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Sensory disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Carboplatin Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Shock haemorrhagic 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Sinus tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Skin burning sensation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Skin exfoliation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Small intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Somnolence 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Squamous cell carcinoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Staphylococcal infection 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Stomatitis 1.0 1.0 1.0 0.0 1.0 0.0 0.0 Carboplatin Supraventricular tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Swollen tongue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Syncope 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Tachypnoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Throat irritation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Throat tightness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Thrombocytosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Thrombosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Carboplatin Toxic epidermal necrolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Transaminases increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Transient ischaemic attack 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Treatment failure 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Carboplatin Tremor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Troponin increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Tubulointerstitial nephritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Carboplatin Tumour lysis syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Unresponsive to stimuli 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Upper respiratory tract infection 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Urinary incontinence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Urinary tract infection 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Urine output decreased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Urosepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Urticaria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Vaginal haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Ventricular extrasystoles 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Ventricular fibrillation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Ventricular tachycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Vision blurred 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboplatin Visual acuity reduced 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carboplatin Vomiting 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Weight increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carboplatin Wheezing 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Carboplatin White blood cell count decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carboplatin White blood cell count increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboprost tromethamine Abdominal pain upper 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carboprost tromethamine Chest discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carboprost tromethamine Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carboprost tromethamine Diarrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carboprost tromethamine Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carboprost tromethamine Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carboprost tromethamine Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carboprost tromethamine Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carboprost tromethamine Vomiting 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carfilzomib Abdominal pain 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Acute coronary syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Acute kidney injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Acute myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Acute pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Acute respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Alanine aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Anaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Angina pectoris 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Carfilzomib Aphasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Arrhythmia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Aspartate aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Asthenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Atelectasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Atrial fibrillation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Atrial flutter 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Atrioventricular block 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Back pain 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Blood bilirubin increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Blood creatinine increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Blood pressure abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Blood pressure decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Bone pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Bradycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Bronchitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib C-reactive protein increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Cardiac disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Cardiac failure acute 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Cardiac failure congestive 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Cardiogenic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Cardiomegaly 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Cardiotoxicity 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Cardiovascular disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carfilzomib Cellulitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Cerebral ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Cerebrovascular accident 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Chest pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Chronic kidney disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Chronic obstructive pulmonary disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Clostridium difficile colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Clostridium difficile infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Confusional state 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Constipation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Contusion 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Carfilzomib Coronary artery disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Decreased appetite 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Decubitus ulcer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Deep vein thrombosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Delirium 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Diarrhoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Diplopia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Disorientation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Disseminated intravascular coagulation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Diverticulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Dysgeusia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carfilzomib Dyspepsia 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Carfilzomib Dyspnoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Ear infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Encephalopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Epistaxis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Extravasation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Fatigue 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Carfilzomib Febrile neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Haemolysis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carfilzomib Haemolytic anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Haemoptysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Haemorrhage intracranial 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Headache 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Heart rate irregular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Hepatic enzyme increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Hepatic function abnormal 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Herpes zoster 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Hypercalcaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Hyperglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Hyperkalaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Hypertension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Hypertensive crisis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Hyperthermia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Hypocalcaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Hypokalaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Hyponatraemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Hypotension 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Hypoxia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Influenza 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Insomnia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Left ventricular dysfunction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Lethargy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Leukopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Liver disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Liver function test abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Localised infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Lower respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Lung disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Lung infection 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Lung infiltration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Lymphocyte count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Lymphopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Mental status changes 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Muscle spasms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Myalgia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Myelodysplastic syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Myocardial ischaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Nasopharyngitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Carfilzomib Nausea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Neuropathy peripheral 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Neutrophil count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Oedema peripheral 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Oral pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Oropharyngeal pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Oxygen saturation decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Carfilzomib Pancytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Phlebitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carfilzomib Plasma cell myeloma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Platelet count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Pleural effusion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Pneumonia aspiration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Pneumonitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Polyneuropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carfilzomib Posterior reversible encephalopathy syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Productive cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Pulmonary congestion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Pulmonary embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Pulmonary hypertension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Pyrexia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Renal disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Renal impairment 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Respiratory distress 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Respiratory tract infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Sinus bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Sinusitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Sleep disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Somnolence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Carfilzomib Stomatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Subarachnoid haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Subdural haematoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Supraventricular tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Swelling face 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Thrombotic thrombocytopenic purpura 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Treatment failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Troponin increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Tumour lysis syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Unevaluable event 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Upper respiratory tract infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carfilzomib Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carfilzomib White blood cell count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carglumic acid Acidosis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Carglumic acid Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carglumic acid Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carglumic acid Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carglumic acid Hypotension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carglumic acid Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carglumic acid Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carglumic acid Metabolic disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Carglumic acid Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carglumic acid Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carglumic acid Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carglumic acid Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carglumic acid Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carglumic acid Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carglumic acid Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carglumic acid Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carglumic acid Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cariprazine Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cariprazine Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cariprazine Delusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cariprazine Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cariprazine Mania 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cariprazine Psychotic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cariprazine Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cariprazine Suicidal ideation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cariprazine Tardive dyskinesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cariprazine Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carisoprodol Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carisoprodol Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carisoprodol Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carisoprodol Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carisoprodol Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carisoprodol Cyanosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carisoprodol Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carisoprodol Depressed level of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carisoprodol Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carisoprodol Drug withdrawal syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carisoprodol Hypotension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carisoprodol Hypoxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carisoprodol Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carisoprodol Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carisoprodol Muscle twitching 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carisoprodol Pneumonia aspiration 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carisoprodol Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carisoprodol Respiratory distress 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carisoprodol Sinus tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carisoprodol Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carisoprodol Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carisoprodol Tachypnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carisoprodol Unresponsive to stimuli 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Carisoprodol Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carmustine Brain oedema 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Carmustine Cerebral haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carmustine Cerebral infarction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Carmustine Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carmustine Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carmustine Encephalopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carmustine Febrile neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carmustine Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carmustine Interstitial lung disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carmustine Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carmustine Speech disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Abdominal discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Acute respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Alanine aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Angina pectoris 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Angioedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carvedilol Arrhythmia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Ascites 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Asthenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Atrial fibrillation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Atrioventricular block 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Atrioventricular block complete 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Atrioventricular block first degree 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Atrioventricular block second degree 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Blood creatinine increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Blood glucose increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Blood potassium increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Blood pressure abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Blood pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carvedilol Bradycardia 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Carvedilol Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Cardiac failure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Cardiogenic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Catatonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Chronic obstructive pulmonary disease 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Circulatory collapse 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Coagulopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Cognitive disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Coma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Depressed level of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Diabetes mellitus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Diarrhoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Dizziness 0.0 0.0 1.0 0.0 0.0 1.0 0.0 Carvedilol Drug abuse 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Drug-induced liver injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Dry mouth 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Fluid retention 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Haemodynamic instability 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Haemorrhage intracranial 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Heart rate decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Hyperkalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Hypokalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Hypotension 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Carvedilol Hypovolaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Hypoxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Intentional self-injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Lethargy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Loss of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Mental impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Mental status changes 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Metabolic acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Mobility decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Muscle spasms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Musculoskeletal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Musculoskeletal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Nausea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Nightmare 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carvedilol Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Pain in extremity 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Palpitations 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Peripheral coldness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Pneumonia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Premature baby 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Carvedilol Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Psoriasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Renal failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Renal impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Sinus bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Carvedilol Syncope 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol Wheezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Carvedilol phosphate Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Caspofungin C-reactive protein increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Caspofungin Drug reaction with eosinophilia and systemic symptoms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Caspofungin Drug resistance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Caspofungin Febrile neutropenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Caspofungin Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Caspofungin Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Caspofungin Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Caspofungin Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Caspofungin acetate Aspartate aminotransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Caspofungin acetate Blood alkaline phosphatase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Caspofungin acetate Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Caspofungin acetate Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Caspofungin acetate Febrile neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Caspofungin acetate Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Caspofungin acetate Hypokalaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Caspofungin acetate Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Caspofungin acetate Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Caspofungin acetate Pyrexia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Caspofungin acetate Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Caspofungin acetate Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Caspofungin acetate Renal impairment 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Caspofungin acetate Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Caspofungin acetate Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Caspofungin acetate Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Caspofungin acetate White blood cell count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefaclor Anaphylactic reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cefaclor Urticaria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefadroxil Drug reaction with eosinophilia and systemic symptoms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefadroxil Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cefazolin Acute generalised exanthematous pustulosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefazolin Acute hepatic failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefazolin Acute kidney injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefazolin Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Cefazolin Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefazolin Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefazolin Cardiac arrest 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefazolin Cardio-respiratory arrest 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefazolin Circulatory collapse 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefazolin Clostridium difficile infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefazolin Coagulopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefazolin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cefazolin Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefazolin Drug-induced liver injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefazolin Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefazolin Erythema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cefazolin Haemolytic anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefazolin Hypotension 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Cefazolin Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefazolin Rash generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefazolin Renal tubular necrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefazolin Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefazolin Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefazolin Urticaria 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Cefazolin sodium Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefazolin sodium Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefazolin sodium Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefazolin sodium Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefdinir Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cefepime hydrochloride Aphasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefepime hydrochloride Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefepime hydrochloride Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefepime hydrochloride Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefepime hydrochloride Myoclonus 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Cefepime hydrochloride Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefepime hydrochloride Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefepime hydrochloride Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefepime hydrochloride Renal impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefepime hydrochloride Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefepime hydrochloride Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefotaxime sodium Agranulocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefotaxime sodium Alanine aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefotaxime sodium Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefotaxime sodium Aspartate aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefotaxime sodium Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefotaxime sodium Blood lactate dehydrogenase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefotaxime sodium Blood urea increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefotaxime sodium Candida infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefotaxime sodium Diarrhoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefotaxime sodium Eosinophilia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cefotaxime sodium Gamma-glutamyltransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefotaxime sodium Leukopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefotaxime sodium Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefotaxime sodium Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefotaxime sodium Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cefotaxime sodium Rash 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cefotaxime sodium Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefotaxime sodium Toxic epidermal necrolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefotaxime sodium Vomiting 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cefpodoxime Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefpodoxime proxetil Asthenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefpodoxime proxetil Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefpodoxime proxetil Leukocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefpodoxime proxetil Pyrexia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefpodoxime proxetil Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefprozil Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefprozil Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftaroline fosamil Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceftaroline fosamil Neutropenia 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Ceftaroline fosamil Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceftaroline fosamil Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceftazidime Chest pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceftazidime Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceftazidime Diarrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceftazidime Dyspnoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftazidime Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftazidime Pyrexia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftazidime Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceftazidime Status epilepticus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Acute generalised exanthematous pustulosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Acute kidney injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Acute respiratory distress syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Agranulocytosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Alanine aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Altered state of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Ceftriaxone Anaphylactic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Aspartate aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Asphyxia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Asthma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Blister 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Blood alkaline phosphatase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Blood pressure decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Bone marrow failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Brain oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone C-reactive protein increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Chest discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Cholecystitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ceftriaxone Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Cholestasis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Circulatory collapse 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Clostridium difficile colitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Coagulopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Cyanosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Death 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Dehydration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Depressed level of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Dermatitis bullous 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Disseminated intravascular coagulation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Drug eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Drug hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Drug interaction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Drug resistance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Drug-induced liver injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ceftriaxone Dyspnoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Electrocardiogram QT prolonged 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ceftriaxone Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Erythema multiforme 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Febrile neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Gamma-glutamyltransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Haematoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Haemodynamic instability 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Haemolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Haemolytic anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Hepatitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Hypersensitivity 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Hypoxia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Leukocytosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Leukopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Lip swelling 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Liver disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Liver function test increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Loss of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Meningitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Mental status changes 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Metabolic acidosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Muscle spasms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Osteomyelitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Oxygen saturation decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Platelet count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Pleural effusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Pneumonia 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Ceftriaxone Premature baby 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Ceftriaxone Premature delivery 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Pruritus generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Pseudomembranous colitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Rash 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Ceftriaxone Rash erythematous 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Rash generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Rash pruritic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Renal impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Respiratory arrest 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Respiratory distress 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Status epilepticus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ceftriaxone Stevens-Johnson syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Stress cardiomyopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Tachypnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Toxic epidermal necrolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Transaminases increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Treatment failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Unresponsive to stimuli 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Urticaria 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Ceftriaxone Ventricular fibrillation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone Wheezing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone sodium Acute generalised exanthematous pustulosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone sodium Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone sodium Agranulocytosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone sodium Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone sodium Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Ceftriaxone sodium Chills 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone sodium Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone sodium Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone sodium Coagulopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone sodium Diarrhoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone sodium Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone sodium Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone sodium Haemolytic anaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone sodium Hyperhidrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ceftriaxone sodium Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone sodium Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone sodium Leukopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone sodium Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone sodium Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone sodium Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone sodium Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone sodium Thrombocytopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ceftriaxone sodium Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceftriaxone sodium Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefuroxime Agranulocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefuroxime Alanine aminotransferase increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cefuroxime Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefuroxime Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cefuroxime Aspartate aminotransferase increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cefuroxime Blood lactate dehydrogenase increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cefuroxime Blood pressure decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime Brain injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefuroxime Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefuroxime Cholestasis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cefuroxime Circulatory collapse 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cefuroxime Delirium 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cefuroxime Diarrhoea 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Cefuroxime Drug hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cefuroxime Drug resistance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cefuroxime Dysgeusia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cefuroxime Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefuroxime Dyspnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cefuroxime Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cefuroxime Flushing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime Haematocrit decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefuroxime Hepatic enzyme increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime Hypersensitivity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cefuroxime Hypersensitivity vasculitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefuroxime Hypoaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefuroxime Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime Jaundice 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cefuroxime Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime Lip swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefuroxime Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime Malaise 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cefuroxime Muscular weakness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cefuroxime Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cefuroxime Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefuroxime Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefuroxime Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cefuroxime Paralysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefuroxime Pneumonia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cefuroxime Pruritus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cefuroxime Pruritus generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefuroxime Rash 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cefuroxime Rash maculo-papular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cefuroxime Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime Respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime Retinal detachment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cefuroxime Shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime Stress cardiomyopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefuroxime Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime Tachypnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefuroxime Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime Toxic epidermal necrolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefuroxime Upper respiratory tract infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime Urticaria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cefuroxime Visual acuity reduced 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cefuroxime Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cefuroxime Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cefuroxime axetil Abdominal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime axetil Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime axetil Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime axetil Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime axetil Chills 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cefuroxime axetil Diarrhoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime axetil Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime axetil Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime axetil Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime axetil Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime axetil Rash 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cefuroxime axetil Stevens-Johnson syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime axetil Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime axetil Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime axetil Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cefuroxime sodium Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime sodium Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime sodium Pyrexia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime sodium Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cefuroxime sodium Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Abasia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Celecoxib Abdominal discomfort 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Celecoxib Abdominal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Abdominal pain lower 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Acute coronary syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Acute hepatic failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Acute myocardial infarction 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Agranulocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Celecoxib Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Arrhythmia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Celecoxib Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Celecoxib Arthropathy 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Celecoxib Ascites 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Asthma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Blood bilirubin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Blood cholesterol increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Blood creatine phosphokinase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Celecoxib Blood creatinine increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Blood potassium increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Blood pressure decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Burning sensation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib C-reactive protein increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Cardiac arrest 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Cardiac disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Cardiovascular disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Carpal tunnel syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Celecoxib Cataract 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Celecoxib Cerebral infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Cerebrovascular accident 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Chest discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Chills 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Cognitive disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Colitis ischaemic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Confusional state 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Contusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Cough 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Crohn's disease 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Cyst 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Celecoxib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Deep vein thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Delirium 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Depressed mood 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Celecoxib Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Celecoxib Diarrhoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Disturbance in attention 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Drug eruption 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Drug hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Celecoxib Drug interaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Celecoxib Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Drug-induced liver injury 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Dry eye 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Dysphagia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Dyspnoea exertional 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Ear pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Emotional distress 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Epistaxis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Erythema 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Eye disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Eye haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Celecoxib Eye pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Eye swelling 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Feeling abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Feeling cold 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Fracture 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Celecoxib Frequent bowel movements 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Celecoxib Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Generalised tonic-clonic seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Glaucoma 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Haematemesis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Haematocrit decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Haemoglobin decreased 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Celecoxib Haemoptysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Haemorrhage intracranial 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Haemorrhagic stroke 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Hallucination 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Celecoxib Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Hemiparesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Hepatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Hepatitis cholestatic 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Hepatocellular injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Herpes simplex 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Herpes zoster 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Hip fracture 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Hyperkalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Hypertension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Influenza 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Influenza like illness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Injection site reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Interstitial lung disease 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Irritable bowel syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Ischaemic stroke 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Jaundice 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Joint stiffness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Joint swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Leukopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Liver disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Localised infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Lymphadenopathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Malaise 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Celecoxib Malignant neoplasm progression 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Celecoxib Malnutrition 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Melaena 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Mental disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Celecoxib Metabolic acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Mobility decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Movement disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Multiple fractures 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Muscle spasms 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Celecoxib Muscular weakness 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Celecoxib Musculoskeletal disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Celecoxib Musculoskeletal pain 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Celecoxib Musculoskeletal stiffness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Celecoxib Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Nausea 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Celecoxib Neck pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Celecoxib Nephrotic syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Celecoxib Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Oedema peripheral 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Oesophagitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Osteoarthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Osteoporosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Celecoxib Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Pharyngeal oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Platelet count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Productive cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Psoriasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Celecoxib Pulmonary embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Rash 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Rash maculo-papular 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Rash papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Rash pustular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Red blood cell count decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Renal failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Renal tubular necrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Retinal haemorrhage 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Rheumatoid arthritis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Celecoxib Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Shock haemorrhagic 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Sinus bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Skin discolouration 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Skin exfoliation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Celecoxib Skin lesion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Sleep disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Sneezing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Celecoxib Speech disorder 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Stomatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Suicidal ideation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Swelling face 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Swollen tongue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Throat tightness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Celecoxib Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Tinnitus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Tongue oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Celecoxib Toxic epidermal necrolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Transaminases increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Celecoxib Tremor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Upper gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Upper limb fracture 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Urinary retention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Celecoxib Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Vasculitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Celecoxib Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Visual acuity reduced 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Visual field defect 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Celecoxib Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Celecoxib Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cephalexin Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cephalexin Acute generalised exanthematous pustulosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cephalexin Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cephalexin Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cephalexin Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cephalexin Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cephalexin Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cephalexin Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cephalexin Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cephalexin Blood creatinine increased 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Cephalexin Clostridium difficile colitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cephalexin Clostridium difficile infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cephalexin Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cephalexin Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cephalexin Diarrhoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cephalexin Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cephalexin Drug hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cephalexin Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cephalexin Drug-induced liver injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cephalexin Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cephalexin Erythema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cephalexin Flatulence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cephalexin Haematochezia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cephalexin Haemolytic anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cephalexin Hallucination 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cephalexin Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cephalexin Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cephalexin Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cephalexin Mania 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cephalexin Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cephalexin Metabolic acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cephalexin Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cephalexin Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cephalexin Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cephalexin Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cephalexin Presyncope 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cephalexin Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cephalexin Rash 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Cephalexin Rash erythematous 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cephalexin Respiratory failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cephalexin Seizure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cephalexin Sepsis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cephalexin Stevens-Johnson syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cephalexin Swelling face 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cephalexin Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cephalexin Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cephalexin Thrombotic thrombocytopenic purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cephalexin Toxic epidermal necrolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cephalexin Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cephalexin Urticaria 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Cephalexin Vomiting 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ceritinib Abdominal discomfort 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceritinib Abdominal pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceritinib Acute hepatic failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Acute kidney injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Alanine aminotransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Altered state of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Appendicitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Aspartate aminotransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Asthenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceritinib Back pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Blood bilirubin increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Blood creatinine increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Blood glucose increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib C-reactive protein increased 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Ceritinib Cardiac tamponade 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceritinib Cerebral infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceritinib Confusional state 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Constipation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Dehydration 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ceritinib Diarrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Dizziness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Drug resistance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Dysphagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Dyspnoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ceritinib Eating disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceritinib Enterocolitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceritinib Epilepsy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Fatigue 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Feeling abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Gait disturbance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Haemoglobin decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Haemoptysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Headache 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Hepatic function abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Hyperglycaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceritinib Hypokalaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Hyponatraemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceritinib Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceritinib Interstitial lung disease 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Intestinal perforation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Large intestine perforation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Liver disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Lung disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceritinib Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Malaise 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Mental disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceritinib Metastases to central nervous system 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Metastases to liver 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Metastases to lung 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ceritinib Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Muscular weakness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Musculoskeletal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ceritinib Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Nausea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Neoplasm 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Ceritinib Pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceritinib Pericardial effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceritinib Pericarditis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceritinib Platelet count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Pleural effusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ceritinib Pulmonary embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Pyrexia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Rash 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Renal disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Renal impairment 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Respiratory distress 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Respiratory failure 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Ceritinib Seizure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Somnolence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Stomatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ceritinib Thrombocytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Transaminases increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ceritinib Urinary tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Vomiting 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib Weight decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib White blood cell count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ceritinib White blood cell count increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cetirizine hydrochloride Abdominal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Acute generalised exanthematous pustulosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Ageusia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Alopecia 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Cetirizine hydrochloride Amnesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cetirizine hydrochloride Angioedema 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Cetirizine hydrochloride Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Cetirizine hydrochloride Arthralgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Ataxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cetirizine hydrochloride Back pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cetirizine hydrochloride Blindness 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Blood bilirubin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cetirizine hydrochloride Bronchospasm 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cetirizine hydrochloride Cardiac failure 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Chest pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Chills 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cetirizine hydrochloride Cholestasis 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cetirizine hydrochloride Confusional state 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Conjunctivitis 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Constipation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cetirizine hydrochloride Coordination abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cetirizine hydrochloride Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cetirizine hydrochloride Cystitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cetirizine hydrochloride Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Depression 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Cetirizine hydrochloride Diarrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cetirizine hydrochloride Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Dry skin 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Dysgeusia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cetirizine hydrochloride Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Dysphonia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cetirizine hydrochloride Dysuria 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Eczema 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Epistaxis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Face oedema 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Cetirizine hydrochloride Flushing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cetirizine hydrochloride Glaucoma 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Hallucination 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Cetirizine hydrochloride Headache 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Cetirizine hydrochloride Hepatitis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Cetirizine hydrochloride Hypertension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cetirizine hydrochloride Injury 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Lymphadenopathy 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Metrorrhagia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cetirizine hydrochloride Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Mouth ulceration 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Muscle twitching 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cetirizine hydrochloride Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Myalgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Nausea 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Cetirizine hydrochloride Nightmare 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Cetirizine hydrochloride Palpitations 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Photosensitivity reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cetirizine hydrochloride Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Cetirizine hydrochloride Purpura 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Pyrexia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Rash 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Cetirizine hydrochloride Rash erythematous 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Rash maculo-papular 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Rectal haemorrhage 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Seizure 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Sleep disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Somnolence 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Cetirizine hydrochloride Suicidal ideation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Syncope 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Tachycardia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Thirst 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cetirizine hydrochloride Tinnitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cetirizine hydrochloride Tongue oedema 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Transaminases increased 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Tremor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cetirizine hydrochloride Upper respiratory tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cetirizine hydrochloride Urinary incontinence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Urinary retention 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Urticaria 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Cetirizine hydrochloride Vertigo 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cetirizine hydrochloride Visual field defect 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Vomiting 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cetirizine hydrochloride Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Chlorambucil Anaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Chlorambucil Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Chlorambucil Herpes zoster 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Chlorambucil Lymphopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Chlorambucil Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Chlorambucil Pyrexia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Chloramphenicol Aplastic anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Chlordiazepoxide Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Chlorhexidine Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Chlorhexidine Arthropathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Chlorhexidine Back pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Chlorhexidine Blister 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Chlorhexidine Diarrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Chlorhexidine Discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Chlorhexidine Erythema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Chlorhexidine Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Chlorhexidine Hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Chlorhexidine Pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Chlorhexidine Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Chlorhexidine Rash 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Chlorhexidine Sinusitis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Chlorhexidine Stomatitis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Chlorhexidine Swelling 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Chlorhexidine Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Chlorhexidine gluconate Dysgeusia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Chlorhexidine gluconate Erythema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Chlorhexidine gluconate Hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Chlorhexidine gluconate Injury 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Chlorhexidine gluconate Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Chlorhexidine gluconate Stomatitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Chlorhexidine gluconate Swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Chloroquine Suicide attempt 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Chloroquine phosphate Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Chloroquine phosphate Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Chloroquine phosphate Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Chloroquine phosphate Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Chlorpheniramine Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Chlorpromazine Catatonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Chlorpromazine Neuroleptic malignant syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Chlorthalidone Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Chlorthalidone Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Chlorthalidone Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Chlorthalidone Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Chlorthalidone Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Chlorthalidone Hypokalaemia 0.0 0.0 1.0 0.0 0.0 1.0 0.0 Chlorthalidone Hyponatraemia 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Chlorthalidone Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Chlorthalidone Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Chlorthalidone Inappropriate antidiuretic hormone secretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Chlorthalidone Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Chlorthalidone Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Chlorthalidone Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Chlorthalidone Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Chlorthalidone Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cholecalciferol Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cholestyramine Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cholic acid Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ciclesonide Arthralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ciclesonide Asthma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ciclesonide Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ciclesonide Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ciclesonide Nasal congestion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ciclesonide Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ciclesonide Oropharyngeal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ciclesonide Pharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ciclesonide Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ciclesonide Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ciclesonide Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ciclesonide Weight increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ciclesonide Wheezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cilostazol Acute myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cilostazol Asthenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cilostazol Cerebral infarction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cilostazol Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cilostazol Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cilostazol Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cilostazol Haematemesis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cilostazol Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cilostazol Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cilostazol Hypotension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cilostazol Melaena 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cilostazol Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cilostazol Nausea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cilostazol Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cilostazol Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cilostazol Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cilostazol Shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cilostazol Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cilostazol Tachycardia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cilostazol Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cimetidine Cardiac arrest 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cimetidine Drug abuse 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cimetidine Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cimetidine Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cimetidine Torsade de pointes 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cimetidine Ventricular tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cinacalcet Cerebrovascular accident 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cinacalcet Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cinacalcet Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cinacalcet hydrochloride Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cinacalcet hydrochloride Arrhythmia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cinacalcet hydrochloride Bone disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cinacalcet hydrochloride Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cinacalcet hydrochloride Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cinacalcet hydrochloride Chronic kidney disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cinacalcet hydrochloride Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cinacalcet hydrochloride Dermatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cinacalcet hydrochloride Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cinacalcet hydrochloride Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cinacalcet hydrochloride Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cinacalcet hydrochloride Gastrointestinal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cinacalcet hydrochloride Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cinacalcet hydrochloride Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cinacalcet hydrochloride Hypocalcaemia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Cinacalcet hydrochloride Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cinacalcet hydrochloride Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cinacalcet hydrochloride Limb discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cinacalcet hydrochloride Metastatic neoplasm 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cinacalcet hydrochloride Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cinacalcet hydrochloride Muscle spasms 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cinacalcet hydrochloride Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cinacalcet hydrochloride Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cinacalcet hydrochloride Seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cinacalcet hydrochloride Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cinacalcet hydrochloride Urticaria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cinacalcet hydrochloride Vomiting 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Abdominal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Abdominal distension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Abdominal pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Abdominal pain lower 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Abdominal pain upper 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Abnormal dreams 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ciprofloxacin Acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ciprofloxacin Acute generalised exanthematous pustulosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Acute kidney injury 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Ciprofloxacin Ageusia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Agitation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Agranulocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Alanine aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Alopecia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ciprofloxacin Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Angina pectoris 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Angioedema 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Angiopathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Anorectal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Anxiety 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Ciprofloxacin Apathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Aphasia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Arrhythmia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Arthralgia 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Ciprofloxacin Arthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Arthropathy 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Aspartate aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Ataxia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Atrial fibrillation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Atrial flutter 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Back pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Bladder pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Blister 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Blood bilirubin increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Blood creatine phosphokinase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Blood creatinine increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Blood glucose increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Blood lactate dehydrogenase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ciprofloxacin Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ciprofloxacin Blood potassium increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Body temperature increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Bone disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Bone marrow failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Bone pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Bradycardia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Breast pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Burning sensation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Candida infection 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Cardiac disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Chest pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Chills 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Circulatory collapse 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Clostridium difficile colitis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ciprofloxacin Coagulopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Confusional state 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Conjunctivitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Connective tissue disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Coordination abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Cystitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Deafness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Delirium 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Dementia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Depersonalisation/derealisation disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Depression 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Ciprofloxacin Dermatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Dermatitis exfoliative 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Diplopia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Disorientation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Drug interaction 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Drug intolerance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Dry eye 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Dry skin 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Dysaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Dysgeusia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Dysphagia 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Dyspnoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Dysuria 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Ear pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Electrolyte imbalance 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Eosinophilia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ciprofloxacin Epistaxis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Erythema 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Erythema multiforme 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ciprofloxacin Extrasystoles 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Eye disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Eye irritation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Eye pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Eye swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Eyelid oedema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Fatigue 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Ciprofloxacin Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Flushing 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Fungal infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Gait disturbance 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Ciprofloxacin Gastritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Gastrointestinal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Gastrointestinal haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Gastrointestinal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Generalised tonic-clonic seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Haematuria 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Haemoglobin decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Haemorrhage 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Hallucination 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Hallucination, visual 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Headache 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Ciprofloxacin Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Hepatic function abnormal 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Ciprofloxacin Hepatocellular injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ciprofloxacin Hyperaesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Hyperbilirubinaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ciprofloxacin Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Hypertension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Hypoacusis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Hypocalcaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Hypoglycaemia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Hypotension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Ill-defined disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Immune system disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Inflammation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Injury 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Insomnia 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Ciprofloxacin Intestinal perforation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Intracranial pressure increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Irritability 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Irritable bowel syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Jaundice 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Jaundice cholestatic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ciprofloxacin Joint stiffness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Joint swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Lacrimation increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Lethargy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Leukocytosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Leukopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ciprofloxacin Lipase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ciprofloxacin Liver disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Liver function test abnormal 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ciprofloxacin Liver injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ciprofloxacin Loss of consciousness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Lymphadenopathy 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Malaise 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Malnutrition 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Mania 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Melaena 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Memory impairment 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Mental disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Metabolic disorder 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Micturition urgency 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Migraine 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Mouth ulceration 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Muscle twitching 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Muscular weakness 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Ciprofloxacin Musculoskeletal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Myoclonus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Nausea 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Ciprofloxacin Neck pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Necrosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ciprofloxacin Nephrolithiasis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Nephropathy toxic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ciprofloxacin Nervous system disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Nervousness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Neuritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Neuropathy peripheral 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Ciprofloxacin Neutropenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ciprofloxacin Nightmare 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Ocular hyperaemia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Oedema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Oedema peripheral 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Orthostatic hypotension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Osteoarthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Pain 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Ciprofloxacin Pain in extremity 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Ciprofloxacin Pain in jaw 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Palpitations 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Pancreatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ciprofloxacin Pancytopenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Paraesthesia 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Ciprofloxacin Paranoia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Parosmia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Pericarditis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Pharyngitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Photophobia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Photosensitivity reaction 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ciprofloxacin Pollakiuria 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Polyneuropathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Polyuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ciprofloxacin Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ciprofloxacin Proctalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ciprofloxacin Prothrombin time prolonged 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ciprofloxacin Pruritus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Pseudomembranous colitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Psychotic disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Pulmonary embolism 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ciprofloxacin Pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Purpura 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Ciprofloxacin Pyrexia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Ciprofloxacin Rash 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Ciprofloxacin Rash generalised 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Rash maculo-papular 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ciprofloxacin Red blood cell sedimentation rate increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Renal impairment 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Ciprofloxacin Respiratory arrest 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Respiratory distress 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Restlessness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ciprofloxacin Rhinitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Scab 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Seizure 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Sepsis 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Skin disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Sleep disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Somnolence 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Ciprofloxacin Status epilepticus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Stevens-Johnson syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ciprofloxacin Suicidal ideation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Swelling 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Swollen tongue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Syncope 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Tachycardia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Tenderness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Tendon rupture 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Tendonitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Thirst 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Thrombocytopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ciprofloxacin Tinnitus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Torsade de pointes 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Toxic epidermal necrolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Transaminases increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ciprofloxacin Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Tubulointerstitial nephritis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ciprofloxacin Urinary incontinence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ciprofloxacin Urinary tract disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Urticaria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Vascular purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ciprofloxacin Vasculitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Ventricular arrhythmia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ciprofloxacin Ventricular fibrillation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin Vertigo 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Vision blurred 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Visual acuity reduced 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin Vomiting 0.0 1.0 1.0 1.0 0.0 1.0 0.0 Ciprofloxacin Vulvovaginal candidiasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ciprofloxacin White blood cell count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ciprofloxacin hydrochloride Abdominal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Abdominal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Ageusia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Agitation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Anaphylactic reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ciprofloxacin hydrochloride Arthralgia 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Ciprofloxacin hydrochloride Asthenia 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Ciprofloxacin hydrochloride Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Blood creatinine increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Chest pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Chills 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Confusional state 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Deafness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Depersonalisation/derealisation disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Diplopia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Dry eye 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Dysgeusia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Dysphagia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Dyspnoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Eye pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Flatulence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ciprofloxacin hydrochloride Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Gastrointestinal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Haemoglobin decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Hallucination 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Hyperaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Hyperhidrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Hypersensitivity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Hypertension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Hypotension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Injury 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Ciprofloxacin hydrochloride Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Irritability 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Joint stiffness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Lethargy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Lymphadenopathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Muscle twitching 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Muscular weakness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Neck pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Nephrolithiasis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Nervousness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Ciprofloxacin hydrochloride Nightmare 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Pain in extremity 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Ciprofloxacin hydrochloride Palpitations 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Photophobia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Photosensitivity reaction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Psychotic disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Pulmonary embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Pyrexia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Rash 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Renal failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Restlessness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ciprofloxacin hydrochloride Seizure 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Stevens-Johnson syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Syncope 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Tachycardia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Tendon rupture 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Ciprofloxacin hydrochloride Tendonitis 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Ciprofloxacin hydrochloride Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Toxic epidermal necrolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Urticaria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Visual acuity reduced 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ciprofloxacin hydrochloride Vomiting 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cisatracurium besylate Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisatracurium besylate Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisatracurium besylate Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisatracurium besylate Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Abdominal discomfort 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Abdominal distension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Abdominal pain lower 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Abdominal pain upper 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Abdominal tenderness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Abscess 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Acute coronary syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Acute hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Acute kidney injury 1.0 1.0 1.0 0.0 0.0 1.0 0.0 Cisplatin Acute myeloid leukaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Acute myocardial infarction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Acute respiratory failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Ageusia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Agranulocytosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Alanine aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Alopecia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Cisplatin Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Aphasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Aspartate aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Aspiration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Asthenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Atelectasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Atrial fibrillation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Bacteraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Balance disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cisplatin Blood alkaline phosphatase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Blood creatinine increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Blood potassium increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Blood pressure decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Blood pressure increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Blood sodium decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Blood urea increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Blood urine present 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Bone marrow failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin C-reactive protein increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Candida infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Cardiogenic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Cardiomegaly 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Cardiomyopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Cardiopulmonary failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Cardiotoxicity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Cerebral infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Cerebrovascular accident 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Chest pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Choking 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Cholangitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Chronic kidney disease 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Chronic obstructive pulmonary disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Clostridium difficile colitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Colitis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Colitis ischaemic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Coma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Confusional state 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Cyanosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Cystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Deafness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cisplatin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Decreased appetite 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Deep vein thrombosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cisplatin Diarrhoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Disease recurrence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Disorientation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Disseminated intravascular coagulation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Diverticulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Drug intolerance 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Drug resistance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cisplatin Dyspepsia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Dysphagia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Dyspnoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Dyspnoea exertional 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Eating disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Encephalopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Enteritis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Enterocolitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Extravasation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cisplatin Face oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Facial paralysis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cisplatin Failure to thrive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Fatigue 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Febrile neutropenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Feeding disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Flank pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Fungal infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Gastrooesophageal reflux disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Generalised oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Generalised tonic-clonic seizure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Haematemesis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Haematochezia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Haematuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Haemoglobin decreased 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Cisplatin Haemoptysis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Headache 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Hemiparesis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Hemiplegia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Hepatotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cisplatin Hydronephrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Hyperglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Hyperkalaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Hyperthermia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Hypoacusis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cisplatin Hypoaesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cisplatin Hypoalbuminaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Hypocalcaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Hypomagnesaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Hypophosphataemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Hypotension 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Hypothyroidism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cisplatin Hypovolaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Hypoxia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Ileus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Inappropriate antidiuretic hormone secretion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Interstitial lung disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Intestinal obstruction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Intestinal perforation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Ischaemic stroke 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Cisplatin Lactic acidosis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Left ventricular dysfunction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Leukocytosis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Leukopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Liver disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Loss of consciousness 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Lower respiratory tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Lung disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Lymphocyte count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Lymphopenia 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Cisplatin Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Malnutrition 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Melaena 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Metabolic acidosis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Metastases to central nervous system 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Metastases to liver 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Metastases to lung 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Mouth ulceration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Mucosal inflammation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Muscle spasms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Musculoskeletal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Myelodysplastic syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Nausea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Neck pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cisplatin Neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Neutrophil count decreased 1.0 0.0 1.0 1.0 0.0 0.0 0.0 Cisplatin Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Oesophagitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Oliguria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Oral candidiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Oral pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Oropharyngeal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Oxygen saturation decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Pallor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Pancytopenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Paraesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Paralysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Pelvic pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Peripheral ischaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Peripheral sensory neuropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cisplatin Peritonitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Pharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Platelet count decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Pleural effusion 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Pneumocystis jirovecii pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Pneumonia bacterial 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Pneumonitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Pollakiuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Polyuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Posterior reversible encephalopathy syndrome 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Proctalgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Productive cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Pruritus 0.0 0.0 1.0 0.0 0.0 1.0 0.0 Cisplatin Pulmonary alveolar haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Pulmonary congestion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Pulmonary embolism 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Pulmonary hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Pulmonary mass 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Pyelonephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Rash erythematous 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Rash pruritic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Renal failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Renal impairment 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Renal tubular necrosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Respiratory disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Respiratory distress 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Respiratory failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Restlessness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Retching 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Rhinorrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Salivary hypersecretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Seizure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Sinus tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Skin discolouration 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cisplatin Sleep disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cisplatin Small intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Squamous cell carcinoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Staphylococcal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Stomatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Tachycardia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Thrombophlebitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cisplatin Treatment failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Tumour lysis syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Unresponsive to stimuli 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Upper gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Urine output decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Vaginal haemorrhage 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Vertigo 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Visual impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cisplatin Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cisplatin Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cisplatin White blood cell count decreased 1.0 0.0 1.0 1.0 0.0 0.0 0.0 Cisplatin White blood cell count increased 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Abortion spontaneous 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Citalopram hydrobromide Acne 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Acute kidney injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Ageusia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Aggression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Agitation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Akathisia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Alopecia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Amenorrhoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Amnesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Apathy 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Asthma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Citalopram hydrobromide Atrial fibrillation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Back pain 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Citalopram hydrobromide Bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Breast pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Bronchitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Bursitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Citalopram hydrobromide Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Catatonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Cerebrovascular accident 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Chills 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Coagulopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Confusional state 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Coordination abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Decreased appetite 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Delirium 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Delusion 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Depersonalisation/derealisation disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Disturbance in attention 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Dry eye 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Dry mouth 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Citalopram hydrobromide Duodenal ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Dyskinesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Dyspnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Electrocardiogram QT prolonged 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Erectile dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Eructation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Euphoric mood 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Extrapyramidal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Extrasystoles 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Eye pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Flatulence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Citalopram hydrobromide Flushing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Gait disturbance 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Galactorrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Citalopram hydrobromide Gastric ulcer 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Generalised tonic-clonic seizure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Gingival bleeding 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Citalopram hydrobromide Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Hallucination 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Headache 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Citalopram hydrobromide Hepatic enzyme increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Citalopram hydrobromide Hepatitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Hot flush 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Hypersensitivity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Hypertension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Hypoglycaemia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Hypokinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Hypothyroidism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Citalopram hydrobromide Increased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Influenza like illness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Insomnia 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Citalopram hydrobromide Jaundice 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Leukopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Libido decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Micturition disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Citalopram hydrobromide Migraine 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Citalopram hydrobromide Muscle spasms 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Mydriasis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Myocardial ischaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Myoclonus 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Citalopram hydrobromide Nausea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Neuralgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Nightmare 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Citalopram hydrobromide Nystagmus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Obesity 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Oedema peripheral 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Oesophagitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Palpitations 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Paraesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Paranoia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Photophobia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Pollakiuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Priapism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Pruritus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Psoriasis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Psychotic disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Pulmonary embolism 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Pyrexia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Rash 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Rhabdomyolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Rhinitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Salivary hypersecretion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Citalopram hydrobromide Skin discolouration 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Sleep disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Somnolence 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Citalopram hydrobromide Suicide attempt 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Syncope 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Torsade de pointes 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Transient ischaemic attack 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Tremor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Upper respiratory tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Citalopram hydrobromide Urinary incontinence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Urinary retention 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Citalopram hydrobromide Vaginal haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Ventricular arrhythmia 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Vertigo 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Visual impairment 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Citalopram hydrobromide Vomiting 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Weight decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Citalopram hydrobromide Weight increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Citalopram hydrobromide Withdrawal syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cladribine Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cladribine Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cladribine Cystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cladribine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cladribine Dyspnoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cladribine Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cladribine Herpes zoster 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cladribine Hypothyroidism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cladribine Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cladribine Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cladribine Localised infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cladribine Lower respiratory tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cladribine Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cladribine Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cladribine Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cladribine Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cladribine Sepsis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cladribine Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cladribine Swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cladribine Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cladribine Urosepsis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cladribine Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cladribine White blood cell count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Abdominal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Clarithromycin Abdominal distension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Abdominal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Abdominal pain upper 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Clarithromycin Abnormal faeces 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Abortion spontaneous 0.0 0.0 0.0 0.0 1.0 0.0 1.0 Clarithromycin Acne 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Acute coronary syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Acute generalised exanthematous pustulosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Acute hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Acute kidney injury 1.0 1.0 1.0 1.0 0.0 0.0 0.0 Clarithromycin Acute respiratory distress syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Acute respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Ageusia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Aggression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Agitation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Agranulocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Alanine aminotransferase increased 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Amylase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Anaphylactic reaction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Clarithromycin Aphasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Arthralgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Ascites 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Aspartate aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Atrioventricular block complete 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Back pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Clarithromycin Balance disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Blindness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Blister 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Blood creatine phosphokinase increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Blood creatinine increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Blood disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Blood glucose decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Blood potassium increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Bone marrow failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Bronchospasm 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Burning sensation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Candida infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Chest discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Chills 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Choking 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Circulatory collapse 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Clostridium difficile colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Clostridium difficile infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Coagulopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Confusional state 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Conjunctival hyperaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Conjunctivitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Constipation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Contusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Crying 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Cyanosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Deafness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Death 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Delusion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Depersonalisation/derealisation disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Depressed mood 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Depression 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Clarithromycin Dermatitis bullous 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Diplopia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Disease progression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Disorientation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Disseminated intravascular coagulation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Disturbance in attention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Clarithromycin Dizziness postural 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Drug abuse 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Drug eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Drug hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Drug interaction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Drug reaction with eosinophilia and systemic symptoms 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Drug resistance 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Drug-induced liver injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Clarithromycin Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Dysgeusia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Clarithromycin Dyskinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Dysphagia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Eating disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Emotional distress 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Encephalopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Epilepsy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Eructation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Erythema multiforme 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Face oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Clarithromycin Feeding disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Feeling hot 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Flatulence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Flushing 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Frequent bowel movements 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Gastric disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Gastrointestinal disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Gastrooesophageal reflux disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Generalised tonic-clonic seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Gingival bleeding 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Glossodynia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Haematemesis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Haematoma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Haematuria 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Haemodynamic instability 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Haemoglobin decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Haemoptysis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Clarithromycin Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Hallucination 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Hallucination, auditory 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Hallucination, visual 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Headache 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Clarithromycin Heart rate increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Hepatic function abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Hepatitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Hepatocellular injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Hepatomegaly 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Hepatotoxicity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Herpes zoster 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Hot flush 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Hyperkalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Hypoacusis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Hypoaesthesia oral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Hypoglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Ileus paralytic 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Insomnia 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Clarithromycin Intracranial pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Irritability 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Jaundice cholestatic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Joint swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Laryngeal oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Lethargy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Leukocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Leukopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Lip swelling 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Liver disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Liver function test abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Local swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Loss of consciousness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Lower respiratory tract infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Lymphadenopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Mania 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Metabolic acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Mood swings 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Mouth ulceration 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Clarithromycin Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Muscle twitching 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Musculoskeletal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Musculoskeletal stiffness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Mydriasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Myopathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Myositis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Nausea 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Clarithromycin Nephrotic syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Nightmare 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Clarithromycin Ocular hyperaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Oedema 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Oedema peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Oral discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Pain in extremity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Pain of skin 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Pallor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Palpitations 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Clarithromycin Pancreatitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Pancytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Panic attack 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Paraesthesia oral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Parosmia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Pharyngeal oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Photophobia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Pneumonia aspiration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Pneumothorax 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Presyncope 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Productive cough 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Pseudomembranous colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Psychotic disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Purpura 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Pyrexia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Clarithromycin Rales 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Rash 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Rash erythematous 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Rash generalised 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Rash macular 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Rash maculo-papular 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Rash papular 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Rash pruritic 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Rash pustular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Renal impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Respiratory depression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Respiratory failure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Rheumatoid arthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Salivary hypersecretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Seizure 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Sensory disturbance 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Sepsis 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Sinusitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Skin burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Skin disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Skin exfoliation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Skin lesion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Skin ulcer 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Sleep disorder 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Clarithromycin Sopor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Status epilepticus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Stevens-Johnson syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Stomatitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Suicidal ideation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Suicide attempt 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Swelling 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Swelling face 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Swollen tongue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Syncope 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Tendonitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Tension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Thinking abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Throat irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Throat tightness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Thrombocytopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Thrombosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Tongue discolouration 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Torsade de pointes 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Toxic epidermal necrolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Transaminases increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Tremor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Unresponsive to stimuli 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Upper respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Urinary retention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Ventricular fibrillation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clarithromycin Visual acuity reduced 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Visual field defect 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clarithromycin Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin Vomiting 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Clarithromycin Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clarithromycin Wheezing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clarithromycin White blood cell count increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Clemastine fumarate Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clevidipine Hypoxia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clindamycin Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clindamycin Abdominal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clindamycin Abdominal pain upper 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clindamycin Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clindamycin Abscess 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clindamycin Acute generalised exanthematous pustulosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clindamycin Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clindamycin Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clindamycin Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clindamycin Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clindamycin Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clindamycin Asthenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clindamycin Back pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clindamycin Clostridium difficile colitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clindamycin Clostridium difficile infection 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Clindamycin Crohn's disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clindamycin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clindamycin Diarrhoea 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Clindamycin Drug hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clindamycin Drug intolerance 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clindamycin Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clindamycin Dry skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clindamycin Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clindamycin Dyspnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clindamycin Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clindamycin Erythema 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clindamycin Fatigue 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clindamycin Flatulence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clindamycin Haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clindamycin Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clindamycin Inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clindamycin Leukopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clindamycin Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clindamycin Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clindamycin Pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clindamycin Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clindamycin Rash 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clindamycin Rash generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clindamycin Stevens-Johnson syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clindamycin Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clindamycin Swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clindamycin Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clindamycin Toxic epidermal necrolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clindamycin Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clindamycin Vaginal discharge 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clindamycin Vaginal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clindamycin Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clindamycin hydrochloride Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clindamycin hydrochloride Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clindamycin phosphate Blister 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clindamycin phosphate Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clindamycin phosphate Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clindamycin phosphate Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clobazam Aggression 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Clobazam Amnesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clobazam Aspartate aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clobazam Cerebrovascular accident 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clobazam Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clobazam Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clobazam Depressed mood 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clobazam Disturbance in attention 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Clobazam Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clobazam Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clobazam Epilepsy 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Clobazam Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clobazam Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clobazam Hypothermia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clobazam Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clobazam Memory impairment 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Clobazam Mental disorder 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Clobazam Muscular weakness 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Clobazam Nasopharyngitis 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Clobazam Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clobazam Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Clobazam Pneumonia aspiration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clobazam Respiratory disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clobazam Respiratory failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clobazam Salivary hypersecretion 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clobazam Seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clobazam Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clobazam Status epilepticus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clobazam Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clobazam Tremor 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Clobazam Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clobazam Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clobazam Weight decreased 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Clobazam Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clobetasol Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clobetasol Skin exfoliation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clobetasol propionate Erythema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clobetasol propionate Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clobetasol propionate Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clobetasol propionate Skin burning sensation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clobetasol propionate Skin exfoliation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clofarabine Acute kidney injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clofarabine Acute myeloid leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clofarabine Alanine aminotransferase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clofarabine Anaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clofarabine Aspartate aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clofarabine Atrial fibrillation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clofarabine Blood bilirubin increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clofarabine Blood creatinine increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clofarabine Bone marrow failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clofarabine Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clofarabine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clofarabine Diarrhoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clofarabine Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clofarabine Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clofarabine Febrile neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clofarabine Hepatic function abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clofarabine Herpes zoster 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clofarabine Hypotension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clofarabine Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clofarabine Mucosal inflammation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clofarabine Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clofarabine Nausea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clofarabine Nephropathy toxic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clofarabine Neutropenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clofarabine Oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clofarabine Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clofarabine Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clofarabine Pancytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clofarabine Platelet count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clofarabine Pleural effusion 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clofarabine Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clofarabine Rash 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clofarabine Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clofarabine Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clofarabine Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clofarabine Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clofarabine Skin exfoliation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clofarabine Staphylococcal infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clofarabine Stomatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clofarabine Toxic epidermal necrolysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clofarabine Transaminases increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clofarabine Tumour lysis syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clofarabine Vomiting 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clofarabine White blood cell count decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clofazimine Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clofazimine Asthenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clofazimine Constipation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clofazimine Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clofazimine Diarrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clofazimine Headache 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clofazimine Jaundice 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clofazimine Vomiting 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clofazimine Weight decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clomipramine Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clomipramine Body temperature increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clomipramine Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clomipramine Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clomipramine Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clomipramine Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clomipramine Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clomipramine Depressed level of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clomipramine Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clomipramine Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clomipramine Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clomipramine Hypertonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clomipramine Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clomipramine Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clomipramine Mydriasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clomipramine Myoclonus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clomipramine Neuroleptic malignant syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clomipramine Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clomipramine Respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clomipramine Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clomipramine Seizure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clomipramine Serotonin syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clomipramine Sinus tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clomipramine Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clomipramine Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clomipramine Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clomipramine Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clomipramine hydrochloride Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clomipramine hydrochloride Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clomipramine hydrochloride Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Abasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Abdominal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Abdominal distension 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Clonazepam Abdominal pain 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Clonazepam Abdominal pain upper 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Abnormal dreams 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clonazepam Acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Acute respiratory failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Affect lability 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Clonazepam Aggression 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Clonazepam Agitation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Akathisia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Alanine aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Alopecia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Altered state of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Amnesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonazepam Anaphylactic reaction 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Clonazepam Anger 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonazepam Anuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Apathy 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Aphasia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Apnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Arthralgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Aspartate aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Asthma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Ataxia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonazepam Back pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Balance disorder 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Clonazepam Blood alkaline phosphatase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clonazepam Blood bilirubin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Blood creatine phosphokinase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Blood potassium decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonazepam Blood pressure decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Blood pressure increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonazepam Bradyphrenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Brain injury 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Bronchitis 0.0 0.0 1.0 0.0 1.0 0.0 0.0 Clonazepam Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonazepam Cardiac disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Cardiac failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clonazepam Catatonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Cerebrovascular accident 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonazepam Chest discomfort 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Chest pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Chills 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Coagulopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonazepam Cognitive disorder 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Clonazepam Coma 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clonazepam Confusional state 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Constipation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Contusion 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Coordination abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Crying 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Cyanosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clonazepam Decreased appetite 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Deep vein thrombosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clonazepam Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Delirium 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Delusion 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Depersonalisation/derealisation disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Depressed level of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Depressed mood 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Dermatitis contact 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Diplopia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clonazepam Discomfort 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Disorientation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Disturbance in attention 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Clonazepam Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Drug abuse 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Drug dependence 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Drug hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonazepam Drug intolerance 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Drug withdrawal syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Clonazepam Dysarthria 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Dysgeusia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Dyskinesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Dysphagia 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Clonazepam Dysphoria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Dyspnoea 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Clonazepam Dysstasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Dystonia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Ear infection 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Clonazepam Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonazepam Emotional disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Emotional distress 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Encephalopathy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Epilepsy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonazepam Erectile dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Face oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clonazepam Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Fear 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Feeding disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Feeling abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Feeling hot 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Clonazepam Feeling jittery 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Flatulence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonazepam Flushing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clonazepam Foetal growth restriction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Gait disturbance 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Clonazepam Gastric disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Gastrointestinal disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Gastrointestinal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Generalised tonic-clonic seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonazepam Haemorrhage 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Clonazepam Hallucination 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Hallucination, auditory 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Heart rate increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Heart rate irregular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clonazepam Hemiparesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Hyperkalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonazepam Hypertension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Hyperthermia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonazepam Hypertonia 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Clonazepam Hypoaesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Hypoglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Hypokinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Hypothermia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Hypotonia 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Clonazepam Immune system disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Incontinence 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Infection 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Influenza like illness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Insomnia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Intentional self-injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Irritability 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Irritable bowel syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Lethargy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonazepam Leukocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Liver function test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Loss of consciousness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Lung disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Malaise 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Mania 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Memory impairment 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Clonazepam Mental disorder 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Clonazepam Mental impairment 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Metabolic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonazepam Migraine 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Miosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Mood altered 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Mood swings 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Movement disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Multiple fractures 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clonazepam Muscle rigidity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Muscle spasms 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Muscle twitching 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Muscular weakness 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Musculoskeletal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Musculoskeletal stiffness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Myalgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Mydriasis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Myoclonus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Nasopharyngitis 0.0 0.0 1.0 0.0 1.0 0.0 0.0 Clonazepam Nausea 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Clonazepam Nervous system disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Nervousness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Clonazepam Neuroleptic malignant syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Nightmare 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Nystagmus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Obstructive airways disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Oedema peripheral 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonazepam Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Oxygen saturation decreased 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Clonazepam Pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Pallor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Palpitations 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Pancreatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clonazepam Panic attack 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Paraesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Paranoia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Parkinson's disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clonazepam Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Platelet count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonazepam Pneumonia 0.0 1.0 1.0 0.0 1.0 0.0 0.0 Clonazepam Pneumonia aspiration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Pollakiuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Poor quality sleep 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Clonazepam Pruritus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Psychotic disorder 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Clonazepam Pulmonary embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonazepam Pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clonazepam Pyrexia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Clonazepam Rales 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Renal failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonazepam Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonazepam Respiratory depression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonazepam Respiratory distress 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonazepam Respiratory failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Respiratory tract congestion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clonazepam Restless legs syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Restlessness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Rhinitis 0.0 0.0 1.0 0.0 1.0 0.0 0.0 Clonazepam Salivary hypersecretion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonazepam Sedation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonazepam Seizure 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Serotonin syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Sinus bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Sinus tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Skin burning sensation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Skin discolouration 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Sleep disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Sneezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Somnolence 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Sopor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Speech disorder 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Clonazepam Stress 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Clonazepam Suicidal ideation 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Clonazepam Suicide attempt 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Swelling face 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Swollen tongue 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Clonazepam Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Tachycardia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Tachypnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Tension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Thirst 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clonazepam Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonazepam Tinnitus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Toothache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Transaminases increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Treatment failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clonazepam Tremor 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Clonazepam Unevaluable event 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Unresponsive to stimuli 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonazepam Urinary incontinence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Urinary retention 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Urticaria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Ventricular tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clonazepam Vertigo 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Vision blurred 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Visual impairment 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Vomiting 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Clonazepam Weight decreased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam Weight increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clonazepam White blood cell count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clonazepam Withdrawal syndrome 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Clonidine Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonidine Agitation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonidine Apnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonidine Arrhythmia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonidine Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonidine Asthma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clonidine Blood creatine phosphokinase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonidine Bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clonidine Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonidine Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonidine Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonidine Constipation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clonidine Delirium 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonidine Depressed level of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonidine Dizziness 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Clonidine Drug hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clonidine Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonidine Erythema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clonidine Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clonidine Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonidine Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clonidine Hypertension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clonidine Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clonidine Hypotonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonidine Lethargy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonidine Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonidine Mental status changes 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clonidine Metabolic acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonidine Miosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clonidine Nausea 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Clonidine Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonidine Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonidine Pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clonidine Pyrexia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonidine Respiratory depression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonidine Respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonidine Sedation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonidine Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonidine Sinus bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clonidine Somnolence 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clonidine Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clonidine Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonidine Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonidine Upper respiratory tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clonidine Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonidine hydrochloride Asthma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clonidine hydrochloride Bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clonidine hydrochloride Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonidine hydrochloride Constipation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clonidine hydrochloride Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonidine hydrochloride Depression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonidine hydrochloride Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clonidine hydrochloride Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clonidine hydrochloride Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonidine hydrochloride Pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clonidine hydrochloride Sinus bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonidine hydrochloride Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonidine hydrochloride Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clonidine hydrochloride Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clopidogrel bisulfate Acute hepatic failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clopidogrel bisulfate Agranulocytosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clopidogrel bisulfate Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clopidogrel bisulfate Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clopidogrel bisulfate Arthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clopidogrel bisulfate Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clopidogrel bisulfate Blood creatinine increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clopidogrel bisulfate Bronchospasm 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clopidogrel bisulfate Cerebral haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clopidogrel bisulfate Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clopidogrel bisulfate Colitis ulcerative 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clopidogrel bisulfate Confusional state 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Clopidogrel bisulfate Contusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clopidogrel bisulfate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clopidogrel bisulfate Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clopidogrel bisulfate Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clopidogrel bisulfate Duodenal ulcer 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clopidogrel bisulfate Dysgeusia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clopidogrel bisulfate Eczema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clopidogrel bisulfate Epistaxis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clopidogrel bisulfate Eye haemorrhage 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Clopidogrel bisulfate Gastric ulcer 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clopidogrel bisulfate Gastrointestinal haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Clopidogrel bisulfate Haematoma 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clopidogrel bisulfate Haematuria 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clopidogrel bisulfate Haemoglobin decreased 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Clopidogrel bisulfate Haemorrhage 1.0 1.0 0.0 0.0 0.0 1.0 0.0 Clopidogrel bisulfate Haemorrhage intracranial 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clopidogrel bisulfate Haemorrhagic stroke 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clopidogrel bisulfate Hallucination 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clopidogrel bisulfate Headache 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clopidogrel bisulfate Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clopidogrel bisulfate Hypotension 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Clopidogrel bisulfate Interstitial lung disease 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clopidogrel bisulfate Liver function test abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clopidogrel bisulfate Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clopidogrel bisulfate Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clopidogrel bisulfate Pancytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clopidogrel bisulfate Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clopidogrel bisulfate Rash erythematous 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clopidogrel bisulfate Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clopidogrel bisulfate Retinal haemorrhage 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clopidogrel bisulfate Stevens-Johnson syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clopidogrel bisulfate Stomatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clopidogrel bisulfate Thrombotic thrombocytopenic purpura 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clopidogrel bisulfate Toxic epidermal necrolysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clopidogrel bisulfate Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clotrimazole Haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clozapine Abdominal discomfort 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Abdominal distension 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Abdominal tenderness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Abnormal faeces 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clozapine Abscess 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Acute coronary syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Acute myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Acute respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Aggression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Agranulocytosis 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Clozapine Akathisia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Alanine aminotransferase increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Altered state of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Anaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clozapine Anger 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Angina pectoris 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Appendicitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Arthropathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Aspartate aminotransferase increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Asphyxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Aspiration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Asthenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Asthma 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Ataxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Atelectasis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Atrial fibrillation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Atrial flutter 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Atrial septal defect 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Clozapine Atrioventricular block complete 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Bacteraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Bacterial infection 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Blood albumin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Blood alkaline phosphatase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Blood bilirubin increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Blood creatine phosphokinase increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Blood creatinine increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Blood disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clozapine Blood lactate dehydrogenase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Blood pressure abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Blood pressure decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Blood pressure fluctuation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Blood urea increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Blood urine present 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Body temperature decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clozapine Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Bone marrow failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Bradyphrenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Brain injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Brain oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Breast cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Bronchitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Bronchospasm 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine C-reactive protein increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Cachexia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Cardiac disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Cardiac failure acute 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Cardiac failure congestive 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Cardiac tamponade 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Cardiogenic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Cardiomegaly 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Cardiomyopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Cardiopulmonary failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Cardiotoxicity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Cardiovascular disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Catatonia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Cerebrovascular accident 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Chest pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Choking 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Cholangitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Cholecystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Chronic kidney disease 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Chronic obstructive pulmonary disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Circulatory collapse 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Clostridium difficile infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Colitis ischaemic 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Coma 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Congestive cardiomyopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Constipation 1.0 0.0 1.0 0.0 0.0 1.0 0.0 Clozapine Coronary artery disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Cough 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Crohn's disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Decubitus ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Deep vein thrombosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Delirium 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Delusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Dementia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Depressed level of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Depression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Dermatitis contact 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clozapine Diabetic ketoacidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Disease recurrence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Disturbance in attention 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Drug intolerance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Drug resistance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clozapine Drug withdrawal syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Dry mouth 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Dry skin 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Dysarthria 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Dyskinesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clozapine Dysphagia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Dysphonia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clozapine Dyspnoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Dystonia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clozapine Eating disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Ejection fraction decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Electrocardiogram abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Electrolyte imbalance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Embolism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Emotional distress 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Encephalitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Encephalopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Epilepsy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clozapine Euphoric mood 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Extrapyramidal disorder 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Face oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Faecaloma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Failure to thrive 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Fatigue 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Febrile neutropenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Feeling abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Femur fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Flat affect 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Flatulence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Fluid retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Gallbladder disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Gastric cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Gastric disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Gastroenteritis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Gastrointestinal haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Generalised tonic-clonic seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Granulocytopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clozapine Haematemesis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Haemodynamic instability 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Haemoglobin decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clozapine Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Hallucination, auditory 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Hallucination, visual 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Headache 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Hemiparesis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clozapine Hepatic cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Hepatic cirrhosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Hepatic encephalopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Hepatic steatosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Hepatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Hernia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Hip fracture 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Hot flush 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Hydronephrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clozapine Hypercalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Hypercholesterolaemia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clozapine Hyperglycaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Hyperhidrosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Hyperkalaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Hyperlipidaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Hypernatraemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Hyperpyrexia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clozapine Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Hyperthermia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Hyperthyroidism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clozapine Hypertonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Hypertriglyceridaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Hyperventilation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Hypophagia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Hypothermia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Hypothyroidism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Hypotonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Hypoxia 0.0 1.0 1.0 0.0 1.0 0.0 0.0 Clozapine Ileus 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Ileus paralytic 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Ill-defined disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Immune thrombocytopenic purpura 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clozapine Inappropriate antidiuretic hormone secretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Increased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Inflammation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Influenza like illness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Intentional self-injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Intervertebral disc protrusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Intestinal obstruction 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Intestinal perforation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Intracranial pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Irritability 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Ischaemic stroke 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Joint swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Laboratory test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Laceration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Lactic acidosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Large intestine perforation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Left ventricular dysfunction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Leukocytosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clozapine Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Clozapine Liver function test increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Localised infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Loss of consciousness 1.0 1.0 1.0 0.0 1.0 0.0 0.0 Clozapine Lower respiratory tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Lung disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Lung infiltration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Lymphadenopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Lymphocyte count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Lymphopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Malignant melanoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Malignant neoplasm progression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Malnutrition 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Mania 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Menorrhagia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clozapine Mental disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Mental impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Metabolic acidosis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Metabolic disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clozapine Metastases to central nervous system 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Metastases to liver 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Metastases to lung 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Metastatic neoplasm 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Migraine 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Miosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Mood altered 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Mood swings 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Myalgia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Myelodysplastic syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Myocardial ischaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Myocarditis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Myoclonus 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Myopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Myositis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Nasal congestion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Nasopharyngitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Nausea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Neck pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Necrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Neoplasm 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Neuroleptic malignant syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Clozapine Neutrophil count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clozapine Obesity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Oedema peripheral 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Clozapine Oesophagitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Oropharyngeal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Orthostatic hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Osteoarthritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Osteomyelitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Osteoporosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Oxygen saturation decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Pallor 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Palpitations 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Pancreatic carcinoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Pancreatitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Pancreatitis acute 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Pancytopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Paralysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Paranoia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Parkinson's disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Pericardial effusion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Pericarditis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Peripheral swelling 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Peritonitis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Personality change 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clozapine Platelet count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clozapine Pleural effusion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Pleurisy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Pneumonia 1.0 1.0 1.0 0.0 0.0 1.0 0.0 Clozapine Pneumonia aspiration 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Pneumonia bacterial 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Pneumonitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Pneumothorax 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Prostate cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Prothrombin time prolonged 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Psychomotor hyperactivity 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Psychotic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Pulmonary congestion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Pulmonary embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Pulmonary fibrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Pulmonary hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Pulmonary mass 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Pyelonephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Pyrexia 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Clozapine Rales 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Rash 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clozapine Red blood cell sedimentation rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Renal disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Renal failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Renal impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Renal tubular necrosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Respiratory depression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Respiratory disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Respiratory distress 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Respiratory failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Restlessness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Salivary hypersecretion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Sedation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Sepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Serotonin syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Sexual dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clozapine Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Sinus tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Skin ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Sleep apnoea syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Sleep disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Clozapine Small intestinal obstruction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Somnolence 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Sopor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Speech disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Spinal fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Staphylococcal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Status epilepticus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Stress 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Stupor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Subarachnoid haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Subdural haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Suicidal ideation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Suicide attempt 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Supraventricular tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Syncope 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Tachycardia 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Clozapine Tachypnoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Tardive dyskinesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Clozapine Thinking abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Thrombocytopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clozapine Thrombosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Tooth disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clozapine Transaminases increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Treatment failure 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Clozapine Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Troponin increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Tubulointerstitial nephritis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Unresponsive to stimuli 1.0 1.0 1.0 0.0 1.0 0.0 0.0 Clozapine Upper gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Clozapine Upper limb fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Upper respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Urosepsis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Vaginal haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Ventricular extrasystoles 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Clozapine Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Vision blurred 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Clozapine Vomiting 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Clozapine Wheezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Clozapine White blood cell count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Clozapine Withdrawal syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cobimetinib Alopecia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cobimetinib Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cobimetinib Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cobimetinib Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cobimetinib Blood creatine phosphokinase increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cobimetinib Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cobimetinib Cardiac failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cobimetinib Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cobimetinib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cobimetinib Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cobimetinib Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cobimetinib Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cobimetinib Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cobimetinib Myalgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cobimetinib Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cobimetinib Photosensitivity reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cobimetinib Pneumonitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cobimetinib Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cobimetinib Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cobimetinib Rash generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cobimetinib Renal failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cobimetinib Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cobimetinib Stomatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cobimetinib Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cobimetinib Visual field defect 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cobimetinib Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Codeine Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Codeine Confusional state 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Codeine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Codeine Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Codeine Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Codeine Drug hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Codeine Dyspnoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Codeine Hallucination 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Codeine Hyperhidrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Codeine Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Codeine Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Codeine Respiratory depression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Codeine Vomiting 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Colchicine Abdominal pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Colchicine Acute kidney injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Colchicine Acute respiratory distress syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Colchicine Alopecia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Colchicine Asthenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Colchicine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Colchicine Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Colchicine Diarrhoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Colchicine Disseminated intravascular coagulation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Colchicine Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Colchicine Gout 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Colchicine Hepatic function abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Colchicine Hypotension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Colchicine Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Colchicine Myopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Colchicine Nausea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Colchicine Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Colchicine Pancytopenia 1.0 1.0 0.0 0.0 0.0 1.0 0.0 Colchicine Rhabdomyolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Colchicine Shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Colchicine Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Colchicine Vomiting 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Colesevelam hydrochloride Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Colesevelam hydrochloride Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Colesevelam hydrochloride Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Colistimethate sodium Paraesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Copper Anaemia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Copper Back pain 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Copper Dysmenorrhoea 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Copper Haemorrhage 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Copper Metrorrhagia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Copper Muscle spasms 0.0 0.0 0.0 0.0 0.0 1.0 1.0 Copper Pain 0.0 0.0 0.0 0.0 0.0 1.0 1.0 Copper Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Copper Vaginal discharge 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Copper Vaginal infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Corticotropin Acne 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Corticotropin Cardiac disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Corticotropin Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Corticotropin Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Corticotropin Fluid retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Corticotropin Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Corticotropin Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Corticotropin Increased appetite 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Corticotropin Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Corticotropin Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Corticotropin Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Corticotropin Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Corticotropin Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Corticotropin Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cosyntropin Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crisaborole Burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Crisaborole Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Crizotinib Abdominal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Abdominal pain upper 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Abscess 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Acute hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Acute respiratory distress syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Acute respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Alanine aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Amnesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Crizotinib Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Appendicitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Arrhythmia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Aspartate aminotransferase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Asthenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Atelectasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Crizotinib Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Back pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Balance disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Blindness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Crizotinib Blood pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Crizotinib Blood urea increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Crizotinib Bone marrow failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Crizotinib Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Brain oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib C-reactive protein increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Cachexia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Candida infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Cardiac disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Cardiac failure congestive 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Cardiopulmonary failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Cerebral infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Circulatory collapse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Coma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Confusional state 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Constipation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Cough 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Deep vein thrombosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Delirium 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Depressed level of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Depression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Diarrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Disease progression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Diverticulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Dysgeusia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Dysphagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Encephalopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Enterocolitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Erythema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Face oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Fatigue 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Febrile neutropenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Feeding disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Feeling abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Gastric disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Generalised oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Haemoptysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Crizotinib Headache 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Hepatic enzyme increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Hepatic function abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Hepatitis fulminant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Hepatotoxicity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Herpes zoster 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Hyperglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Hyperkalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Hypoalbuminaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Hypocalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Hyponatraemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Hypotension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Hypothyroidism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Crizotinib Hypoxia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Ileus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Interstitial lung disease 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Intestinal obstruction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Intestinal perforation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Ischaemic stroke 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Jaundice 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Large intestine perforation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Liver disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Liver function test abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Liver injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Loss of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Lower respiratory tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Lung disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Lung infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Lymphopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Malaise 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Malnutrition 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Memory impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Mental disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Musculoskeletal stiffness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Nausea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Nervous system disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Neutrophil count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Oedema peripheral 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Oesophagitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Platelet count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Pleural effusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Pneumocystis jirovecii pneumonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Pneumonitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Pneumothorax 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Pulmonary alveolar haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Pulmonary embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Renal disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Crizotinib Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Respiratory disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Rhabdomyolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Sciatica 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Stomatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Swelling 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Crizotinib Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Thrombosis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Urinary tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Vomiting 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib Weight increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Crizotinib White blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Abdominal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Anxiety 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Depressed level of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Depressed mood 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Diarrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclobenzaprine Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Dizziness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Drug hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Dysarthria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Gait disturbance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Loss of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Malaise 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Mental impairment 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Nausea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Paraesthesia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Respiratory depression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Sedation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Serotonin syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Sinus tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Somnolence 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Cyclobenzaprine Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Tachycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Unresponsive to stimuli 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclobenzaprine Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclobenzaprine hydrochloride Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclopentolate Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclopentolate Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclopentolate Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclopentolate hydrochloride Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Agranulocytosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclophosphamide Alopecia 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclophosphamide Amenorrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclophosphamide Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Atrial fibrillation 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Cyclophosphamide Bacterial infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Blood bilirubin increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Body temperature increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Bone marrow failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Bradycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide C-reactive protein increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Cardiac failure congestive 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Cardiogenic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Cardiomyopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Cardiotoxicity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Colitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Confusional state 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Conjunctivitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Constipation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Cystitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclophosphamide Diarrhoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Disseminated intravascular coagulation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Dizziness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Encephalopathy 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Enteritis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Enterocolitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Erythema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Extravasation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Febrile neutropenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Fluid overload 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Fluid retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Foetal death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Haematuria 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Cyclophosphamide Haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Headache 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Hepatic function abnormal 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Cyclophosphamide Hepatitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Hepatomegaly 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Herpes zoster 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Hot flush 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclophosphamide Hyperbilirubinaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Hyperkalaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Hypoacusis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclophosphamide Hypoaesthesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Hypotension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Hypoxia 1.0 1.0 1.0 1.0 0.0 0.0 0.0 Cyclophosphamide Infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Inflammation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Interstitial lung disease 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Jaundice 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Lymphoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Malaise 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Mouth ulceration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Mucosal inflammation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Myalgia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Myelodysplastic syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Myocarditis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Neoplasm 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Nephropathy toxic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclophosphamide Neurotoxicity 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Oropharyngeal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Pancytopenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Pericardial effusion 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Platelet count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Pleural effusion 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Posterior reversible encephalopathy syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Pulmonary embolism 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Pulmonary haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Pulmonary hypertension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Renal impairment 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Respiratory distress 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Respiratory failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Rhinorrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Seizure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Stomatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Swelling face 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Tachycardia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Tenderness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Thrombocytopenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Toxic epidermal necrolysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Toxic skin eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Tremor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Tumour lysis syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Venous thrombosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Ventricular fibrillation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Viral infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclophosphamide Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cyclophosphamide Weight increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Abdominal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cyclosporine Abdominal distension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Abdominal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Abdominal pain upper 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Abscess 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclosporine Acne 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cyclosporine Acute myeloid leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Acute pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclosporine Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Agranulocytosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Alanine aminotransferase increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cyclosporine Alopecia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Altered state of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cyclosporine Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Angioedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Anuria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Anxiety 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Aplastic anaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Appendicitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclosporine Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Cyclosporine Arthropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Ascites 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Aspartate aminotransferase increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cyclosporine Asthenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cyclosporine Atrial fibrillation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cyclosporine Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cyclosporine Bacteraemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Bacterial infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Basal cell carcinoma 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cyclosporine Blindness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cyclosporine Blood bilirubin increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Blood lactate dehydrogenase increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cyclosporine Blood pressure decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Blood pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Blood urea increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Bone marrow failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Brain oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine C-reactive protein increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cyclosporine Candida infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Cardiac failure congestive 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Cardiovascular disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Cellulitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Cerebral infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Cerebrovascular accident 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclosporine Cerebrovascular disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclosporine Cholestasis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Circulatory collapse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Clostridium difficile infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Cognitive disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclosporine Colon cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Coma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Confusional state 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Conjunctivitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Constipation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Contusion 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cyclosporine Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Cystitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Deafness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cyclosporine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Decreased appetite 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cyclosporine Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cyclosporine Depressed level of consciousness 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Cyclosporine Dermatitis exfoliative 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Diarrhoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Disease recurrence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Disorientation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Disseminated intravascular coagulation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Disturbance in attention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Diverticulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclosporine Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Drug eruption 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Cyclosporine Drug hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Cyclosporine Drug intolerance 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Cyclosporine Drug resistance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Dry eye 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Cyclosporine Dry skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Dyskinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclosporine Dyspnoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cyclosporine Ear pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Encephalitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Encephalopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Enteritis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Epilepsy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclosporine Erythema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cyclosporine Eye disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Eye irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Eye pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cyclosporine Faeces discoloured 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Febrile neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Feeding disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Feeling abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Feeling hot 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Fluid retention 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Fungal infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cyclosporine Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclosporine Gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Generalised oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Generalised tonic-clonic seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Haematoma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Haemoptysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Haemorrhage intracranial 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cyclosporine Heart rate increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Hemiparesis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Hepatic enzyme increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Hepatic function abnormal 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Hepatitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclosporine Hernia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Herpes simplex 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Herpes zoster 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Hirsutism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Hyperbilirubinaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Hyperkalaemia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Cyclosporine Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Hypertensive crisis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclosporine Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclosporine Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclosporine Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Hypoxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Ileus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Immune thrombocytopenic purpura 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Inflammation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Insomnia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Interstitial lung disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Intestinal perforation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Intracranial pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclosporine Irritability 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Jaundice 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Lacrimation increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Laryngitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cyclosporine Lethargy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Leukopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Liver disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Liver injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Lung disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Lung infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Lung infiltration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Lymphadenopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Lymphoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Lymphopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Malignant melanoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Malnutrition 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Melaena 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclosporine Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cyclosporine Metabolic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Metastases to lung 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Migraine 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Mobility decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cyclosporine Mouth ulceration 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Mucosal inflammation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Muscle spasms 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cyclosporine Musculoskeletal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Myelodysplastic syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Myocarditis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Nail disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Nasopharyngitis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Cyclosporine Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cyclosporine Neck pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Nephropathy toxic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Nervous system disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Nervousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Ocular hyperaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Oedema peripheral 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cyclosporine Oropharyngeal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Oxygen saturation decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cyclosporine Pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Pain in extremity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclosporine Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclosporine Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cyclosporine Pericardial effusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cyclosporine Photophobia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Pigmentation disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Plasma cell myeloma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Platelet count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Pleural effusion 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Pneumocystis jirovecii pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Pneumonia aspiration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclosporine Pneumonia bacterial 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Pneumonitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Pneumothorax 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Posterior reversible encephalopathy syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 1.0 Cyclosporine Productive cough 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Prostate cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Protein urine present 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Psoriasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Pulmonary embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Pulmonary mass 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Pyrexia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cyclosporine Rash generalised 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Renal tubular necrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclosporine Respiratory disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Respiratory distress 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Respiratory tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclosporine Rheumatoid arthritis 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Shock haemorrhagic 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Sinus congestion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Skin burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Skin cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Skin discolouration 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Skin disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Skin exfoliation 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Skin hyperpigmentation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Skin irritation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cyclosporine Skin mass 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Skin ulcer 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cyclosporine Sleep disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Speech disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cyclosporine Squamous cell carcinoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Staphylococcal infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Stomatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Throat tightness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Thrombotic thrombocytopenic purpura 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Tongue disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cyclosporine Tooth disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Treatment failure 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Cyclosporine Ulcer 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cyclosporine Unresponsive to stimuli 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Urinary tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Urine output decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyclosporine Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cyclosporine Viral infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyclosporine Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cyclosporine Visual acuity reduced 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cyclosporine Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cyclosporine Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cyclosporine White blood cell count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cyproheptadine Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cyproheptadine Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cysteamine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cysteamine Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cysteamine Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cysteamine Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cysteamine Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cysteamine bitartrate Dehydration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cysteamine bitartrate Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cysteamine bitartrate Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cysteamine bitartrate Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cysteamine bitartrate Renal failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cysteamine bitartrate Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Abdominal distension 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Abdominal pain 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Abdominal tenderness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Abscess 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Acidosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Acute myeloid leukaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Acute myocardial infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Acute respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Agitation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Agranulocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Alanine aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Anuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Ascites 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Asthenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Atelectasis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Atrial fibrillation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Atrial flutter 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Back pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Bacteraemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Bacterial infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Blood bilirubin increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Blood count abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Blood creatinine increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Blood pressure decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Bone marrow failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Bone pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Bradycardia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Brain injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Brain oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Candida infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Cardiac disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Cardiac failure acute 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Cardiac failure congestive 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Cardiac tamponade 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Cardio-respiratory arrest 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Cardiogenic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Cardiomyopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Cardiotoxicity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Cellulitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Cerebral haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Cerebral infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Chills 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Cholecystitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Cholestasis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Circulatory collapse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Clostridium difficile colitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Clostridium difficile infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Coagulopathy 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Colitis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Confusional state 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Constipation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Contusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Cough 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Cyanosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Decreased appetite 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Deep vein thrombosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Depressed level of consciousness 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Diarrhoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Disease recurrence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Disseminated intravascular coagulation 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Drug hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cytarabine Drug reaction with eosinophilia and systemic symptoms 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Dysarthria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cytarabine Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Ecchymosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Ejection fraction decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Encephalopathy 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Enteritis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Enterocolitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Epistaxis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Erythema 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Fatigue 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Febrile neutropenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Fluid overload 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Fungal infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Gait disturbance 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Cytarabine Gamma-glutamyltransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Generalised oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Generalised tonic-clonic seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Haematochezia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Haematuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Haemodynamic instability 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Haemoglobin decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Haemoptysis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Haemorrhage intracranial 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Headache 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Hepatotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cytarabine Hyperbilirubinaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Hyperkalaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Hyperpyrexia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cytarabine Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Hypophagia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Hypotension 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Hypoxia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Ileus 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Interstitial lung disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Intestinal obstruction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Intestinal perforation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Jaundice 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Lactic acidosis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Leukocytosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Cytarabine Leukopenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Lipase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Lung infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Lung infiltration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Malaise 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Cytarabine Melaena 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Meningitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Menorrhagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Mental status changes 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Metabolic acidosis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Mouth ulceration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Mucosal inflammation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Muscular weakness 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Cytarabine Myalgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Myelodysplastic syndrome 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Cytarabine Myocardial infarction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Myocarditis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Nasal congestion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Nausea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Neck pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Neoplasm progression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Nephropathy toxic 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Nervous system disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cytarabine Neurotoxicity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Neutropenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Neutrophil count decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Oedema peripheral 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Oropharyngeal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Oxygen saturation decreased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Pain 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Pain in extremity 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Pallor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Pancreatitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Pancytopenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Pericardial effusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Peritonitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Petechiae 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Platelet count decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Pleural effusion 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Pneumonia aspiration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Pneumonia bacterial 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Pneumonitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Pneumothorax 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Pulmonary alveolar haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Pulmonary embolism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Pulmonary haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Pulmonary mass 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Pulmonary oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Rash erythematous 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Rectal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Renal failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Respiratory disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Respiratory distress 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Seizure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Sensory loss 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Cytarabine Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Shock haemorrhagic 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Sinus tachycardia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Sinusitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Skin disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Small intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Somnolence 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Splenomegaly 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Staphylococcal infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Stomatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Subarachnoid haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Subdural haematoma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Supraventricular tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Swelling face 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Tachycardia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Tachypnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Treatment failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Troponin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Tumour lysis syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Unresponsive to stimuli 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Upper gastrointestinal haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Urine output decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Urticaria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Ventricular tachycardia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Viral infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Cytarabine Vision blurred 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine Weight increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine White blood cell count decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Cytarabine White blood cell count increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Cytarabine hydrochloride Febrile neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabigatran Cerebral haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabigatran Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabigatran Drug hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabigatran Gastric haemorrhage 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Dabigatran Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabigatran Gastrointestinal haemorrhage 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Dabigatran Gastrooesophageal reflux disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabigatran Haemorrhage 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Dabigatran Haemorrhage intracranial 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabigatran Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dabigatran Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabigatran etexilate Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabigatran etexilate Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabigatran etexilate Haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dabigatran etexilate mesylate Abdominal pain upper 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dabigatran etexilate mesylate Anaphylactic reaction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabigatran etexilate mesylate Angioedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabigatran etexilate mesylate Diarrhoea 1.0 1.0 1.0 0.0 0.0 1.0 0.0 Dabigatran etexilate mesylate Dyspepsia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabigatran etexilate mesylate Gastrointestinal haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabigatran etexilate mesylate Haemorrhage 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Dabigatran etexilate mesylate Nausea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Dabigatran etexilate mesylate Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabigatran etexilate mesylate Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Abdominal pain upper 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Alanine aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dabrafenib Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Aphasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dabrafenib Arthritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Aspartate aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Asthenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib Atrial fibrillation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Basal cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dabrafenib Blood alkaline phosphatase increased 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dabrafenib Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Blood lactate dehydrogenase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib Cardiac failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib Cerebrovascular accident 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Cholecystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Confusional state 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Constipation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib Disseminated intravascular coagulation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Dysphagia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Dyspnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Electrocardiogram QT prolonged 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dabrafenib Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Febrile neutropenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Gamma-glutamyltransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib Gastric haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Haemorrhage intracranial 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib Hypercalcaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib Hyperglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Hyperkalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib Hypoalbuminaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Hypocalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Hypokalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Influenza like illness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Lower respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Lymphadenopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib Malaise 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Malignant melanoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib Metastases to central nervous system 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib Metastases to lung 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib Mobility decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Muscle spasms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Muscular weakness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Nausea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dabrafenib Night sweats 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Pain in extremity 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dabrafenib Pancreatitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib Paraesthesia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Pleural effusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib Pneumonia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Renal failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Respiratory distress 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib Sepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Skin lesion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib Splenomegaly 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Squamous cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dabrafenib Staphylococcal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib Viral infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib Vision blurred 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Abdominal discomfort 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Abdominal pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Abdominal pain upper 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Alopecia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Arthralgia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Aspartate aminotransferase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Asthenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Back pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Basal cell carcinoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Blood alkaline phosphatase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Chills 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Constipation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Cough 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Deep vein thrombosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Diarrhoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Dizziness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Dry mouth 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Dry skin 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Epistaxis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Erythema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Fatigue 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Folliculitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Gamma-glutamyltransferase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Headache 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Hyperglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Hyperhidrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Hyperkalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Hypertension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Hypoalbuminaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Hypokalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Insomnia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Lymphoedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dabrafenib mesylate Lymphopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Malignant melanoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Myalgia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Nasopharyngitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Nausea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Oedema peripheral 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Oropharyngeal pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Pain in extremity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Pulmonary embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Pyrexia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Rash 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Rash pruritic 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Squamous cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dabrafenib mesylate Stomatitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Urinary tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Vision blurred 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dabrafenib mesylate Vomiting 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dacarbazine Diarrhoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dacarbazine Febrile neutropenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dacarbazine Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dacarbazine Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dacarbazine Neutrophil count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dacarbazine Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dacarbazine Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daclatasvir dihydrochloride Diarrhoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Daclatasvir dihydrochloride Headache 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dactinomycin Acute myeloid leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dactinomycin Anaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dactinomycin Bone marrow failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dactinomycin Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dactinomycin Encephalopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dactinomycin Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dactinomycin Respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dactinomycin Thrombocytopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dactinomycin Vomiting 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dalbavancin Hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalbavancin Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalbavancin Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Abasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Abdominal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Abdominal distension 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Acute myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dalfampridine Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Alanine aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Alopecia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Amnesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Anal incontinence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Aphasia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Arthralgia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Arthritis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Arthropathy 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Aspartate aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Asthenia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Ataxia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Back pain 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Bacteraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Balance disorder 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Basal cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dalfampridine Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Blister 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Blood glucose decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Blood glucose increased 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Blood pressure decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Blood pressure increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Blood urine present 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Bone disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dalfampridine Bronchitis 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Burning sensation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dalfampridine Cardiac disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Cataract 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Dalfampridine Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Cerebral haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Cerebrovascular accident 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Chills 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Choking 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dalfampridine Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Chronic obstructive pulmonary disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Clostridium difficile colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Clostridium difficile infection 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Cognitive disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Cold sweat 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Colitis ulcerative 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dalfampridine Confusional state 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Constipation 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Contusion 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Coordination abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Crying 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Cystitis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dalfampridine Decreased appetite 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Decubitus ulcer 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Deep vein thrombosis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Dementia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Depressed mood 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Depression 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Diabetic ketoacidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Diarrhoea 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Diplopia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Disease progression 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Disorientation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Dizziness 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Drug hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Dysarthria 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Dysgeusia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dalfampridine Dyskinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Dysphagia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Dyspnoea 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Dysstasia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Dysuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Emotional distress 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Eye pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Fatigue 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Feeling cold 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Feeling hot 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Feeling jittery 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Femur fracture 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Flushing 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Gait disturbance 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Gastric disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Gastroenteritis viral 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Gastrointestinal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Generalised tonic-clonic seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Haematocrit decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Hallucination 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Headache 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Hemiparesis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Herpes zoster 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Hip fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dalfampridine Hypersomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Hypertension 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Hypoaesthesia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Hypokinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Hypotension 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Ill-defined disorder 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Immune system disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Incontinence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Influenza like illness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Intervertebral disc protrusion 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Joint swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Laceration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Lethargy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Limb discomfort 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dalfampridine Lymphoedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Malaise 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Malignant melanoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dalfampridine Memory impairment 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Mental disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Mental impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Middle insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Mobility decreased 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Mood altered 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Motor dysfunction 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Movement disorder 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Muscle spasms 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Muscle twitching 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Muscular weakness 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Musculoskeletal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Musculoskeletal stiffness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Myocardial infarction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Nasopharyngitis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Nausea 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Neck pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dalfampridine Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dalfampridine Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Neuralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Oedema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Oedema peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Optic neuritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Osteoarthritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Osteoporosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Pain 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Pain in extremity 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Pain in jaw 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dalfampridine Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Panic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Paraesthesia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Peripheral swelling 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Pneumonia aspiration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Pollakiuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Pruritus 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Pruritus generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Pulmonary embolism 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Pyelonephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Pyrexia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Rectal haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dalfampridine Red blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Renal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Renal failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dalfampridine Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dalfampridine Respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dalfampridine Sensory disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Sepsis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dalfampridine Sinusitis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Skin discolouration 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dalfampridine Skin disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Skin ulcer 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Sleep disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Small intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Somnolence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Speech disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Staphylococcal infection 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Stress 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Subdural haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Suicidal ideation 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Dalfampridine Swelling 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dalfampridine Syncope 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Thinking abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Toothache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Transient ischaemic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Troponin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Upper limb fracture 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Urinary incontinence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Urinary retention 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Urinary tract disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Urinary tract infection 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Urosepsis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Urticaria 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Vaginal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Vertigo 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalfampridine Visual acuity reduced 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine Vomiting 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Weight decreased 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dalfampridine Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dalfampridine White blood cell count increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalteparin Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dalteparin Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Abdominal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dapagliflozin Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Angina pectoris 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Asthenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dapagliflozin Back pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Dapagliflozin Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Blood pressure decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dapagliflozin Candida infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dapagliflozin Cellulitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Cerebrovascular accident 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dapagliflozin Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Confusional state 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Dapagliflozin Cystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dapagliflozin Decreased appetite 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dapagliflozin Dehydration 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Dapagliflozin Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dapagliflozin Diabetic ketoacidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Dapagliflozin Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dapagliflozin Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dapagliflozin Dysuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dapagliflozin Flank pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Gastroenteritis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Gastrointestinal disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dapagliflozin Glycosuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dapagliflozin Headache 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dapagliflozin Hyperglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dapagliflozin Hyperkalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dapagliflozin Hypernatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Hypoglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Hypomagnesaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Hypophagia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Hypotension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Dapagliflozin Hypovolaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Lactic acidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Loss of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Malaise 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Metabolic acidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dapagliflozin Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dapagliflozin Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Pancreatic carcinoma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dapagliflozin Pancreatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dapagliflozin Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Pneumonia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Pollakiuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dapagliflozin Polyuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dapagliflozin Proteinuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dapagliflozin Pyelonephritis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Renal disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dapagliflozin Renal failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dapagliflozin Renal impairment 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Dapagliflozin Rhabdomyolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dapagliflozin Sepsis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Septic shock 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Dapagliflozin Somnolence 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Dapagliflozin Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dapagliflozin Tachypnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Thirst 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Dapagliflozin Tremor 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dapagliflozin Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Urinary tract infection 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Urosepsis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dapagliflozin Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin propanediol Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dapagliflozin propanediol Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin propanediol Hypovolaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin propanediol Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin propanediol Nausea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin propanediol Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dapagliflozin propanediol Pyelonephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapagliflozin propanediol Urinary tract infection 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dapsone Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Dapsone Agranulocytosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dapsone Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dapsone Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapsone Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapsone Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapsone Drug hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dapsone Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dapsone Drug-induced liver injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dapsone Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapsone Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dapsone Haemolytic anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dapsone Hepatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dapsone Hypoxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapsone Jaundice 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dapsone Liver injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapsone Lymphadenopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dapsone Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dapsone Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapsone Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapsone Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapsone Pyrexia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dapsone Rash erythematous 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dapsone Rash maculo-papular 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dapsone Renal failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dapsone Respiratory failure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dapsone Sepsis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dapsone Skin exfoliation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dapsone Toxic epidermal necrolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dapsone Ventricular arrhythmia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dapsone Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Acute generalised exanthematous pustulosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Acute respiratory distress syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Acute respiratory failure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Agranulocytosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Alanine aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Aspartate aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Bacteraemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Blood creatine phosphokinase increased 0.0 0.0 1.0 0.0 0.0 1.0 0.0 Daptomycin Blood creatinine increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Blood lactate dehydrogenase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Cardiac failure acute 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Clostridium difficile colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Cough 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Disseminated intravascular coagulation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Drug interaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Drug resistance 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Dyspnoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Eczema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Encephalopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Eosinophilia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Erythema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Fungal infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Generalised oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Haemodynamic instability 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Haemoptysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Hepatic function abnormal 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Hepatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Hepatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Hepatocellular injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Hyperkalaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Hypersensitivity vasculitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Interstitial lung disease 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Lactic acidosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Daptomycin Leukopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Liver function test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Lung disorder 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Lung infiltration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Myalgia 0.0 0.0 1.0 0.0 0.0 1.0 0.0 Daptomycin Myocarditis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Daptomycin Neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Night sweats 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Oral candidiasis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Pancytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Platelet count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Pleural effusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Pneumonitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Pruritus 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Pulmonary embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Rash 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Rash generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Rash maculo-papular 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Rash pruritic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Renal impairment 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Respiratory distress 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Daptomycin Seizure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Skin exfoliation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Staphylococcal infection 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Daptomycin Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Tachypnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Throat tightness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Daptomycin Thrombocytopenia 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Daptomycin Toxic epidermal necrolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Toxic skin eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Transaminases increased 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Daptomycin Treatment failure 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Daptomycin Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Urticaria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Vasculitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daptomycin White blood cell count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Daptomycin White blood cell count increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Darunavir Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Darunavir Acute generalised exanthematous pustulosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Darunavir Angina pectoris 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Darunavir Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Darunavir Drug resistance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Darunavir Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Darunavir Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Darunavir Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Darunavir Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Darunavir Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Darunavir Respiratory failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Darunavir Treatment failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Darunavir ethanolate Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Darunavir ethanolate Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Darunavir ethanolate Stevens-Johnson syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Darunavir ethanolate Vomiting 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dasabuvir Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasabuvir Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Abdominal discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Abdominal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dasatinib Acute kidney injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Acute myeloid leukaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Acute respiratory distress syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Acute respiratory failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dasatinib Arthropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dasatinib Atrial fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Back pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Blindness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dasatinib Blister 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dasatinib Blood cholesterol increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dasatinib Blood creatinine increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Blood pressure decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Blood pressure increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Bone marrow failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Bone pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dasatinib Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Cardiac disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Cardiac failure acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Cardiotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dasatinib Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dasatinib Cerebral haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Chest discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dasatinib Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Chronic obstructive pulmonary disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Clostridium difficile infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Colitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Colitis ulcerative 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dasatinib Colon cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dasatinib Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Decreased appetite 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Diplopia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Disease progression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dasatinib Disseminated intravascular coagulation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dasatinib Drug resistance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dasatinib Dry eye 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dasatinib Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Electrocardiogram abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Enterocolitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dasatinib Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Eye irritation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Eye pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Faeces discoloured 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Febrile neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Feeling abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Fluid retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Full blood count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Gait disturbance 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Gastrooesophageal reflux disease 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Generalised oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Haemoglobin decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dasatinib Heart rate decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Heart rate irregular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dasatinib Hepatotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dasatinib Hernia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dasatinib Hyperaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Hypoaesthesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Hypocalcaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Hypokalaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Hypothyroidism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dasatinib Hypoxia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Ill-defined disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Infection 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Inflammation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Insomnia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Interstitial lung disease 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Lacrimation increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dasatinib Leukaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Liver injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dasatinib Localised infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Lymphoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dasatinib Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Mental disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Migraine 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Muscle spasms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Neoplasm 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dasatinib Nephrotic syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dasatinib Nervousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dasatinib Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Neutrophil count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Night sweats 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Ocular hyperaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dasatinib Oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Oxygen saturation decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Pain in extremity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dasatinib Pancytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Pericardial effusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Platelet count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Pleural effusion 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Dasatinib Pneumocystis jirovecii pneumonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Pneumonitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Dasatinib Premature delivery 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dasatinib Prostate cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dasatinib Pulmonary hypertension 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Dasatinib Pulmonary oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dasatinib Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Renal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Renal impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Skin cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dasatinib Splenomegaly 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Subdural haematoma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Swelling 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Tinnitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dasatinib Treatment failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Tumour lysis syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dasatinib Unevaluable event 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Dasatinib Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dasatinib White blood cell count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Daunorubicin Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daunorubicin Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daunorubicin Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daunorubicin Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daunorubicin Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Daunorubicin Cardiac failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daunorubicin Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daunorubicin Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daunorubicin Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daunorubicin Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daunorubicin Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daunorubicin Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daunorubicin Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daunorubicin Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daunorubicin Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Daunorubicin Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daunorubicin Febrile neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daunorubicin Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daunorubicin Hepatomegaly 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daunorubicin Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daunorubicin Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daunorubicin Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daunorubicin Neutropenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Daunorubicin Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daunorubicin Pancytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daunorubicin Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daunorubicin Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daunorubicin Tachycardia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Daunorubicin Thrombocytopenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Daunorubicin Viral infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Daunorubicin Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Daunorubicin hydrochloride Bone marrow failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Daunorubicin hydrochloride Pyrexia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Decitabine Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Decitabine Acute myeloid leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Decitabine Acute respiratory distress syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Decitabine Anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Decitabine Asthenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Decitabine Bacteraemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Decitabine Bone marrow failure 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Decitabine Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Decitabine Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Decitabine Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Decitabine Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Decitabine Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Decitabine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Decitabine Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Decitabine Diarrhoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Decitabine Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Decitabine Drug resistance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Decitabine Drug-induced liver injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Decitabine Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Decitabine Extravasation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Decitabine Fatigue 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Decitabine Febrile neutropenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Decitabine Haemorrhage intracranial 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Decitabine Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Decitabine Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Decitabine Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Decitabine Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Decitabine Hypoxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Decitabine Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Decitabine Leukocytosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Decitabine Liver injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Decitabine Lung infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Decitabine Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Decitabine Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Decitabine Mucosal inflammation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Decitabine Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Decitabine Nausea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Decitabine Neutropenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Decitabine Pancytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Decitabine Pericardial effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Decitabine Phlebitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Decitabine Platelet count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Decitabine Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Decitabine Pneumonitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Decitabine Pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Decitabine Pyrexia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Decitabine Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Decitabine Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Decitabine Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Decitabine Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Decitabine Staphylococcal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Decitabine Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Decitabine Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Decitabine Vomiting 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Abasia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Abdominal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Abdominal distension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Abdominal tenderness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Deferasirox Acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Acute hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Acute kidney injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Acute myeloid leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Aggression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Deferasirox Alanine aminotransferase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Alopecia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Altered state of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Amnesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Anaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Angina pectoris 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Anorectal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Anuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Anxiety 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Aphasia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Aplastic anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Appendicitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Arthralgia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Arthritis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Aspartate aminotransferase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Asthenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Atrial fibrillation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Back pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Bacteraemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Bacterial infection 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Blister 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Blood alkaline phosphatase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Blood bilirubin increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Blood count abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Blood creatinine increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Blood glucose increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Blood lactate dehydrogenase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Blood magnesium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Blood potassium increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Deferasirox Blood pressure decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Blood urea increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Body temperature increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Bone disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Bone marrow failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Bone pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Breast cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Bronchitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox C-reactive protein increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Cardiac disorder 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Cardiac failure congestive 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Cardiomegaly 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Cardiovascular disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Cellulitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Cerebrovascular accident 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Chest pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Chills 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Cholecystitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Clostridium difficile infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Colitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Colitis ischaemic 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Confusional state 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Contusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Cyanosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Cystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Deafness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Deferasirox Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Decreased appetite 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Depressed level of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Depression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Diabetes mellitus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Diarrhoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Disease progression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Disease recurrence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Diverticulitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Dizziness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Drug hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Drug-induced liver injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Dry skin 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Duodenal ulcer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Dysphonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Dyspnoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Dyspnoea exertional 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Dysstasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Eating disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Encephalopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Epistaxis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Faeces discoloured 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Fatigue 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Febrile neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Feeling abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Femur fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Fluid retention 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Full blood count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Fungal infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Gait disturbance 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Gamma-glutamyltransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Gastric haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Gastric ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Gastrointestinal pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Generalised oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Gingival bleeding 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Haematemesis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Haematocrit decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Haemoglobin decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Haemolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Haemoptysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Haemorrhage intracranial 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Haemorrhoids 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Headache 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Hemiplegia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Hepatic cirrhosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Hepatic encephalopathy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Hepatic function abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Hepatitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Hepatocellular injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Hepatomegaly 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Hip fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Hyperglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Hyperpyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Hypersomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Hyperthermia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Hypoacusis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Hypoaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Hypoalbuminaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Hypoglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Hypokalaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Hypokinesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Hypophagia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Hypophosphataemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Hypoxia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Ill-defined disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Immune system disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Infection 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Inflammation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Intestinal obstruction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Intestinal perforation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Ischaemic stroke 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Jaundice 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Jaundice cholestatic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Laboratory test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Lactic acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Lethargy 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Deferasirox Leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Leukocytosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Leukopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Deferasirox Lipase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Liver disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Liver function test abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Localised infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Loss of consciousness 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Lung disorder 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Lung infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Lymphadenopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Lymphoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Malaise 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Mass 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Memory impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Meningitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Mental status changes 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Metabolic acidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Movement disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Muscular weakness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Musculoskeletal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Myelodysplastic syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Neck pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Nervous system disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Nervousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Neutrophil count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Ocular hyperaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Oedema peripheral 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Oropharyngeal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Osteoarthritis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Oxygen saturation decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Pain in extremity 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Pallor 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Pharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Plasma cell myeloma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Platelet count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Pleural effusion 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Pollakiuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Productive cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Proteinuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Pulmonary embolism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Pulmonary hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Pulmonary oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Pyrexia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Rash generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Rash macular 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Rectal haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Red blood cell count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Renal disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Renal impairment 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Renal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Respiratory distress 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Respiratory tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Retching 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Sinusitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Skin discolouration 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Skin exfoliation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Sleep disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Somnolence 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Speech disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Splenomegaly 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Staphylococcal infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Stomatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Subdural haematoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Swelling 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Throat irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Deferasirox Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Toothache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Transaminases increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Tremor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Unevaluable event 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Urinary retention 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Urine output decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Deferasirox Venous thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Vertigo 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Visual impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Weight decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox Weight increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferasirox White blood cell count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferasirox White blood cell count increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferiprone Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferiprone Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferiprone Agranulocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferiprone Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Deferiprone Arthritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferiprone Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferiprone Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferiprone Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferiprone Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferiprone Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferiprone Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferiprone Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferiprone Epistaxis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferiprone Febrile neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferiprone Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferiprone Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferiprone Leukopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Deferiprone Lymphopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferiprone Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deferiprone Neutropenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Deferiprone Neutrophil count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Deferiprone Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferiprone Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Deferiprone Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferiprone Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferoxamine mesylate Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferoxamine mesylate Diarrhoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Deferoxamine mesylate Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferoxamine mesylate Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deferoxamine mesylate Vomiting 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deflazacort Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deflazacort Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deflazacort Aggression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deflazacort Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deflazacort Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Deflazacort Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deflazacort Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deflazacort Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deflazacort Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deflazacort Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deflazacort Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deflazacort Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deflazacort Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deflazacort Fracture 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Deflazacort Gastroenteritis viral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deflazacort Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deflazacort Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deflazacort Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deflazacort Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deflazacort Osteoporosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Deflazacort Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deflazacort Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deflazacort Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deflazacort Seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Deflazacort Sepsis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deflazacort Spinal compression fracture 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Deflazacort Spinal fracture 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Deflazacort Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deflazacort Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deflazacort Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Degarelix Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Degarelix Anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Degarelix Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Degarelix Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Degarelix Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Degarelix Cardiac failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Degarelix Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Degarelix Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Degarelix Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Degarelix Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Degarelix Hyperglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Degarelix Inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Degarelix Injection site reaction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Degarelix Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Degarelix Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Degarelix Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Degarelix Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Degarelix Renal failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Degarelix Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Degarelix acetate Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Degarelix acetate Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Degarelix acetate Injection site pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Degarelix acetate Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Degarelix acetate Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deoxycholic acid Swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desflurane Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Desflurane Eye irritation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Desloratadine Abdominal pain upper 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Desloratadine Arrhythmia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Desloratadine Bronchitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Desloratadine Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desloratadine Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Desloratadine Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Desloratadine Electrocardiogram QT prolonged 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Desloratadine Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Desloratadine Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Desloratadine Hallucination, auditory 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Desloratadine Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Desloratadine Heart rate increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Desloratadine Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desloratadine Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Desloratadine Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desloratadine Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Desloratadine Intentional self-injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desloratadine Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Desloratadine Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Desloratadine Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Desloratadine Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Desloratadine Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desloratadine Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desloratadine Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desloratadine Sopor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desloratadine Suicidal ideation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Desloratadine Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Desloratadine Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Desloratadine Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desloratadine Vomiting 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Desmopressin Affect lability 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desmopressin Asthenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Desmopressin Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desmopressin Brain injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desmopressin Cognitive disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desmopressin Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desmopressin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Desmopressin Depressed level of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desmopressin Disturbance in attention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desmopressin Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desmopressin Fluid retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desmopressin Hypernatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desmopressin Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desmopressin Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desmopressin Inappropriate antidiuretic hormone secretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desmopressin Insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desmopressin Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desmopressin Mental disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desmopressin Mood swings 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desmopressin Muscle spasms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desmopressin Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desmopressin Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desmopressin Restlessness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desmopressin Sluggishness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desmopressin Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desmopressin Thinking abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desmopressin Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desmopressin acetate Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desmopressin acetate Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desmopressin acetate Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Desogestrel Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Desogestrel Vomiting 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Desvenlafaxine Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Desvenlafaxine Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Desvenlafaxine Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Desvenlafaxine Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Desvenlafaxine Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Desvenlafaxine Suicidal ideation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Desvenlafaxine Withdrawal syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Desvenlafaxine succinate Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Desvenlafaxine succinate Blood pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Desvenlafaxine succinate Decreased appetite 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Desvenlafaxine succinate Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Desvenlafaxine succinate Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Desvenlafaxine succinate Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Desvenlafaxine succinate Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Desvenlafaxine succinate Hallucination 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Desvenlafaxine succinate Headache 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Desvenlafaxine succinate Hyperhidrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Desvenlafaxine succinate Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Desvenlafaxine succinate Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Desvenlafaxine succinate Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Desvenlafaxine succinate Nausea 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Desvenlafaxine succinate Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Desvenlafaxine succinate Somnolence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Desvenlafaxine succinate Tachycardia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Desvenlafaxine succinate Tremor 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Desvenlafaxine succinate Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Desvenlafaxine succinate Weight decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Desvenlafaxine succinate Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Deutetrabenazine Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deutetrabenazine Balance disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Deutetrabenazine Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deutetrabenazine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Deutetrabenazine Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Deutetrabenazine Dyskinesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Deutetrabenazine Feeling abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Deutetrabenazine Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Deutetrabenazine Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Deutetrabenazine Somnolence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Deutetrabenazine Suicidal ideation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Deutetrabenazine Tardive dyskinesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Deutetrabenazine Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Abasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Abdominal distension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Abdominal pain lower 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Abscess 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Acne 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexamethasone Acute coronary syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Acute hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Acute myeloid leukaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Acute myocardial infarction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Acute pulmonary oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Acute respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Anaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Anuria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Aphasia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dexamethasone Appendicitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Ascites 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Aspartate aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Ataxia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Atelectasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Atrial fibrillation 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Atrioventricular block complete 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Bacteraemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Bacterial infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Balance disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Basal cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexamethasone Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Blood alkaline phosphatase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Blood cholesterol increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Blood creatine phosphokinase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Blood creatinine increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Blood glucose decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Blood pressure decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Blood pressure increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Blood triglycerides increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Blood urea increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Bone marrow failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Bone pain 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Bradycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Brain injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Brain oedema 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Bronchitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone C-reactive protein increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Candida infection 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Cardiac failure 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Cardiac failure congestive 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Cardiogenic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Cardiomegaly 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Dexamethasone Cardiotoxicity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Cataract 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Dexamethasone Catatonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Cerebral infarction 1.0 1.0 1.0 1.0 0.0 0.0 0.0 Dexamethasone Cerebral ischaemia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Cerebrovascular accident 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Chills 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Chronic obstructive pulmonary disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Circulatory collapse 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Clostridium difficile colitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Coagulopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Cognitive disorder 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Dexamethasone Colitis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Confusional state 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Conjunctivitis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Cough 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Crying 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexamethasone Cyanosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexamethasone Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexamethasone Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Deep vein thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Dehydration 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Delusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Depressed level of consciousness 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Diabetes mellitus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Diabetic ketoacidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexamethasone Disease recurrence 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexamethasone Disorientation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Disseminated intravascular coagulation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Diverticulitis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Dizziness 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dexamethasone Drug dependence 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Drug hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Drug intolerance 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Drug resistance 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Drug withdrawal syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexamethasone Dysarthria 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Dysgeusia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Dyspepsia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Dysphagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Dyspnoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Ecchymosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Electrolyte imbalance 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Emotional distress 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexamethasone Encephalitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Encephalopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Enterocolitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Epilepsy 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Epistaxis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Erythema 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Eye haemorrhage 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Eye irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexamethasone Eye pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Dexamethasone Facial paralysis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dexamethasone Faecaloma 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Failure to thrive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Febrile neutropenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Femur fracture 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Fluid overload 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Fluid retention 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Foetal death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Foetal growth restriction 1.0 0.0 0.0 0.0 1.0 0.0 1.0 Dexamethasone Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Fungal infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Gait disturbance 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dexamethasone Gamma-glutamyltransferase increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Gastritis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Generalised tonic-clonic seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Glaucoma 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Dexamethasone Haematochezia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Haematuria 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Haemodynamic instability 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Haemoptysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Haemorrhage intracranial 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Hallucination 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Heart rate increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Hemiparesis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dexamethasone Hemiplegia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Hepatic enzyme increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Hepatic function abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Hepatic steatosis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Hepatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Hepatocellular injury 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Hepatomegaly 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Hepatotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexamethasone Herpes simplex 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Hiccups 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Hip fracture 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Hyperbilirubinaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Hypercalcaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Hyperglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Hyperkalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Hyperlipidaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexamethasone Hypernatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Hyperthermia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Hyperuricaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Hypocalcaemia 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Hypoglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Hypotension 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Hypoxia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Ileus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Infection 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Influenza 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Interstitial lung disease 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Intestinal obstruction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Intestinal perforation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Intraocular pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexamethasone Irritability 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Ischaemic stroke 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Jaundice 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Lacrimation increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Lactic acidosis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Lethargy 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Leukocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Liver function test abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Liver function test increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Loss of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Lower respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Lung disorder 1.0 0.0 1.0 1.0 0.0 0.0 0.0 Dexamethasone Lung infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Lung infiltration 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Dexamethasone Lung neoplasm malignant 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Lymphadenopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Lymphopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Malaise 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Mania 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Maternal drugs affecting foetus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexamethasone Memory impairment 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Dexamethasone Meningitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Mental disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Mental status changes 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Metabolic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Metastases to central nervous system 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Migraine 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexamethasone Mobility decreased 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Movement disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Mucosal inflammation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Muscle atrophy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexamethasone Muscular weakness 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Dexamethasone Musculoskeletal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Musculoskeletal stiffness 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Myalgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Myelodysplastic syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Myocardial ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Myopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Necrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Nervous system disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Neurological symptom 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexamethasone Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Neutrophil count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Ocular hyperaemia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Oedema peripheral 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Oesophagitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Oral candidiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Oral pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Oropharyngeal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Orthostatic hypotension 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dexamethasone Osteomyelitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Osteonecrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Oxygen saturation decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Pain 1.0 1.0 1.0 1.0 0.0 0.0 0.0 Dexamethasone Pain in extremity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Palpitations 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Pancreatitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Pancreatitis acute 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Peripheral sensory neuropathy 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Peripheral swelling 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Peritonitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Petechiae 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Pharyngeal oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Photophobia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexamethasone Plasma cell myeloma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Platelet count decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Pleural effusion 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Pneumocystis jirovecii pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Pneumonia aspiration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Pneumonia bacterial 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Pneumonitis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Pneumothorax 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Polyneuropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexamethasone Polyuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Posterior reversible encephalopathy syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 1.0 Dexamethasone Premature delivery 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexamethasone Presyncope 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dexamethasone Productive cough 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Pruritus 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Psychotic disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Pulmonary alveolar haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Pulmonary congestion 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Pulmonary embolism 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Pulmonary haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Pulmonary mass 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Pyrexia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Rash generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Rash macular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Rash pruritic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Renal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Renal impairment 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Respiratory distress 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Respiratory tract infection 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Retinal detachment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Retinal haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexamethasone Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Rhinitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexamethasone Sciatica 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Sensory disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Shock haemorrhagic 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Sinus tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Skin disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexamethasone Skin infection 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Skin ulcer 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Speech disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Staphylococcal infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Status epilepticus 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Stevens-Johnson syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Stomatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Stress cardiomyopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Subdural haematoma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Tachycardia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Tachypnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Throat irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexamethasone Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Thrombophlebitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Thrombosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Tinnitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexamethasone Transaminases increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Treatment failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Tremor 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Tumour lysis syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Unresponsive to stimuli 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Upper gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Urinary incontinence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Urinary tract infection 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Vasculitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Ventricular extrasystoles 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone Vision blurred 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Visual acuity reduced 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Dexamethasone Visual field defect 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexamethasone Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone Vomiting 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Weight decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dexamethasone White blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexamethasone Withdrawal syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexamethasone sodium phosphate Hypoglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexamethasone sodium phosphate Large intestine perforation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexlansoprazole Abdominal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexlansoprazole Abdominal pain upper 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Dexlansoprazole Acute kidney injury 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexlansoprazole Anaphylactic reaction 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Dexlansoprazole Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexlansoprazole Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dexlansoprazole Asthenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexlansoprazole Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexlansoprazole Chronic kidney disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexlansoprazole Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexlansoprazole Constipation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexlansoprazole Crohn's disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexlansoprazole Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexlansoprazole Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexlansoprazole Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexlansoprazole Diabetes mellitus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexlansoprazole Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dexlansoprazole Dizziness 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Dexlansoprazole Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexlansoprazole Dysphagia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexlansoprazole Dyspnoea 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Dexlansoprazole Flatulence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexlansoprazole Gastrooesophageal reflux disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexlansoprazole Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Dexlansoprazole Hypersensitivity 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Dexlansoprazole Hypomagnesaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexlansoprazole Inflammation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dexlansoprazole Muscle spasms 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexlansoprazole Muscular weakness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexlansoprazole Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexlansoprazole Nasopharyngitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexlansoprazole Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dexlansoprazole Oropharyngeal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexlansoprazole Pain in extremity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexlansoprazole Peripheral swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexlansoprazole Pharyngeal oedema 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Dexlansoprazole Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexlansoprazole Pruritus 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Dexlansoprazole Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexlansoprazole Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexlansoprazole Somnolence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexlansoprazole Swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dexlansoprazole Tachycardia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexlansoprazole Throat tightness 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Dexlansoprazole Tremor 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexlansoprazole Urticaria 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Dexlansoprazole Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexmedetomidine Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexmedetomidine Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexmedetomidine Cardiac arrest 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexmedetomidine Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexmedetomidine Electrocardiogram QT prolonged 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexmedetomidine Hyperthermia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexmedetomidine Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexmedetomidine Laryngospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexmedetomidine Polyuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexmedetomidine Withdrawal syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dexmedetomidine hydrochloride Agitation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexmedetomidine hydrochloride Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexmedetomidine hydrochloride Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexmedetomidine hydrochloride Hyperpyrexia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexmedetomidine hydrochloride Hyperthermia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexmedetomidine hydrochloride Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexmedetomidine hydrochloride Hypoxia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexmedetomidine hydrochloride Pyrexia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexmedetomidine hydrochloride Respiratory depression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexmedetomidine hydrochloride Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dexmethylphenidate hydrochloride Aggression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexmethylphenidate hydrochloride Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexmethylphenidate hydrochloride Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexmethylphenidate hydrochloride Irritability 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexmethylphenidate hydrochloride Mood swings 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dexrazoxane Aspartate aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexrazoxane Bone marrow failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexrazoxane Febrile neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexrazoxane Insomnia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexrazoxane Pneumonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dexrazoxane Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dextroamphetamine Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dextroamphetamine Agitation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dextroamphetamine Metabolic acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dextroamphetamine Rhabdomyolysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dextroamphetamine Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dextromethorphan Confusional state 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dextromethorphan Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dextromethorphan Diarrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dextromethorphan Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dextromethorphan Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dextromethorphan Feeling abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dextromethorphan Hallucination 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dextromethorphan Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dextromethorphan Serotonin syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dextrose Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diazepam Abdominal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Abdominal pain upper 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diazepam Acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Acute hepatic failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diazepam Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Acute respiratory failure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diazepam Aggression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diazepam Agitation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diazepam Agranulocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Akathisia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Altered state of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diazepam Amnesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diazepam Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Anger 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diazepam Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Apathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diazepam Aphasia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Apnoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diazepam Arrhythmia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Arthralgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Asphyxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diazepam Aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diazepam Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diazepam Ataxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Atrial fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Atrioventricular block 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Balance disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Blister 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diazepam Blood creatine phosphokinase increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diazepam Blood creatinine increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Blood potassium increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Blood pressure decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diazepam Blood pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diazepam Bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diazepam Bradyphrenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Brain oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Cardiac disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diazepam Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diazepam Cardiogenic shock 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diazepam Cardiomyopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Cardiotoxicity 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diazepam Catatonia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diazepam Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Choking 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Cholecystitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Circulatory collapse 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Cognitive disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diazepam Coma 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diazepam Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diazepam Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Constipation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Coordination abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diazepam Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Crying 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diazepam Cyanosis 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diazepam Decreased appetite 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Delirium 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diazepam Depersonalisation/derealisation disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Depressed level of consciousness 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Diazepam Depressed mood 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diazepam Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Disorientation 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Diazepam Disturbance in attention 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diazepam Drug dependence 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Drug hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diazepam Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Drug withdrawal syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Drug-induced liver injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diazepam Dysarthria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diazepam Dyskinesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Dysphagia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Dysphoria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Dyspnoea 1.0 1.0 0.0 0.0 1.0 0.0 0.0 Diazepam Dystonia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Electrocardiogram QT prolonged 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diazepam Electrocardiogram abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Encephalopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Erythema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Extrapyramidal disorder 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Diazepam Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Feeling abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Foetal death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diazepam Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Gait disturbance 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Gamma-glutamyltransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Gastric disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diazepam Generalised tonic-clonic seizure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diazepam Haemorrhage intracranial 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Hallucination 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diazepam Hallucination, auditory 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diazepam Hallucination, visual 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Heart rate decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Heart rate increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Hepatic encephalopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Hepatic failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Hepatic function abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diazepam Hepatic necrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diazepam Hepatic steatosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diazepam Hepatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Hepatotoxicity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Hot flush 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diazepam Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Hyperkalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Hypernatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diazepam Hypersomnia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diazepam Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Hypertensive crisis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Hyperthermia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diazepam Hypertonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Hypoaesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Hypoglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diazepam Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diazepam Hypokinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diazepam Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Hypotension 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Diazepam Hypothermia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diazepam Hypotonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Hypoxia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diazepam Ill-defined disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diazepam Incontinence 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diazepam Insomnia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Intentional self-injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Intestinal obstruction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Irritability 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Jaundice cholestatic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Joint swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diazepam Lactic acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Lethargy 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Diazepam Loss of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Lung disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Mania 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diazepam Mental disorder 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Diazepam Mental impairment 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diazepam Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Metabolic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Miosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diazepam Mobility decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Mood swings 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Diazepam Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Muscle rigidity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Muscle spasms 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Muscle tightness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diazepam Musculoskeletal stiffness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diazepam Mydriasis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diazepam Myoclonus 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diazepam Nausea 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Diazepam Nervous system disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diazepam Nervousness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diazepam Neuroleptic malignant syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Nightmare 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Nystagmus 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Diazepam Obstructive airways disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Oral discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Oxygen saturation decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diazepam Pallor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Palpitations 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Panic attack 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Diazepam Paraesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Peripheral ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Pneumonia aspiration 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Diazepam Polyuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Premature baby 0.0 0.0 1.0 0.0 1.0 0.0 0.0 Diazepam Pruritus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Psychotic disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Pulmonary congestion 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Pulmonary embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diazepam Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Renal impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Respiratory depression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Respiratory disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diazepam Respiratory distress 0.0 1.0 1.0 0.0 1.0 0.0 0.0 Diazepam Respiratory failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Diazepam Restlessness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diazepam Sedation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Sensory loss 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diazepam Serotonin syndrome 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Diazepam Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Sinus tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diazepam Skin discolouration 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Sleep apnoea syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diazepam Sleep disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Somnolence 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diazepam Sopor 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diazepam Speech disorder 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Diazepam Status epilepticus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Stress 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diazepam Stupor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diazepam Suicidal ideation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Suicide attempt 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diazepam Supraventricular tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Swelling face 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diazepam Tachypnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Tension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Tinnitus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Toxic skin eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazepam Tremor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Unevaluable event 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diazepam Unresponsive to stimuli 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazepam Urinary retention 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Vertigo 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diazepam Vision blurred 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Visual impairment 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazepam Vomiting 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Diazepam Weight decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diazepam Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Diazepam Withdrawal syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diazoxide Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazoxide Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diazoxide Cardiac failure congestive 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diazoxide Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diazoxide Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazoxide Hyperglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazoxide Oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diazoxide Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazoxide Pulmonary hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diazoxide Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dichlorphenamide Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dichlorphenamide Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dichlorphenamide Metabolic acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dichlorphenamide Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dichlorphenamide Paraesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dichlorphenamide Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dichlorphenamide Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Abdominal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Abdominal distension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Abdominal pain upper 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Abdominal tenderness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac Acute coronary syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Acute generalised exanthematous pustulosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Acute hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Acute myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Agitation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Agranulocytosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Amnesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Anal incontinence 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Angina pectoris 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Diclofenac Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Arrhythmia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac Arthralgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Arthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac Asthenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Asthma 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Back pain 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Diclofenac Bacterial infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Balance disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Blindness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac Blister 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Blood bilirubin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Blood cholesterol increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Blood creatine phosphokinase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Blood creatinine increased 0.0 1.0 1.0 0.0 1.0 0.0 0.0 Diclofenac Blood urea increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Body temperature increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac Burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac C-reactive protein increased 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Diclofenac Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Cardiac disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Cardiac failure 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Cerebral infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Chest discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Chest pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Choking 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Chronic kidney disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac Chronic obstructive pulmonary disease 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Circulatory collapse 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Cold sweat 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Colitis ulcerative 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Confusional state 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Conjunctival hyperaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac Contusion 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Coronary artery disease 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Cyanosis 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Diclofenac Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Decreased appetite 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Depressed level of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Depression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Dermatitis exfoliative 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Diplopia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Disease recurrence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac Disorientation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Diverticulitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac Dizziness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Drug abuse 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Drug dependence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac Drug hypersensitivity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Drug intolerance 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Diclofenac Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Drug-induced liver injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Dry eye 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Duodenal ulcer 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Dysaesthesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Dysgeusia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac Dysphagia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Dysphonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Dyspnoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Dyspnoea exertional 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Dysuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Eczema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Electrocardiogram abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Encephalopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Enteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Epistaxis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Eructation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Eye disorder 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac Eye irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac Eye pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Eye pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac Eye swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac Face oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Faeces discoloured 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Diclofenac Feeling abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Feeling hot 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac Flank pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Flatulence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Fluid retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Flushing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Gait disturbance 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Gastric ulcer 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Gastrointestinal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Gastrointestinal haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Haematemesis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Haematochezia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Haematocrit decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Haematoma 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Haematuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Haemoglobin decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Haemolytic anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Heart rate increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Hepatic enzyme increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Hepatic function abnormal 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Hepatic steatosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Hepatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Hepatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Hepatotoxicity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Hot flush 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Hyperkalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Hypersensitivity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Hypertension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Hypoaesthesia 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Diclofenac Hypokalaemia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Diclofenac Hypokinesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Ill-defined disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Inflammation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Insomnia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Intentional self-injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Iron deficiency anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Irritability 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Jaundice 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Joint swelling 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Diclofenac Large intestine perforation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Laryngeal oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac Leukocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Leukopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Limb discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Lip swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac Liver function test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Liver injury 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Melaena 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Memory impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Metabolic acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Mobility decreased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Muscle spasms 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Musculoskeletal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Musculoskeletal stiffness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Diclofenac Myalgia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Nasal congestion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac Nasopharyngitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Nausea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Nephropathy toxic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Nephrotic syndrome 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Diclofenac Nervousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Nodule 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Ocular hyperaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac Oedema 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Oliguria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Oropharyngeal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac Oropharyngeal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Osteoarthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Oxygen saturation decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Pain 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Diclofenac Pain in extremity 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Diclofenac Pallor 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Palpitations 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Paraesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac Paraesthesia oral 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Pericarditis 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Diclofenac Periorbital oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac Peripheral swelling 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Peritonitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Petechiae 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Pharyngeal oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Photosensitivity reaction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Platelet count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Pneumonia aspiration 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Pneumothorax 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Polyuria 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Diclofenac Premature baby 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Diclofenac Presyncope 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Proteinuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Prothrombin time prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Pruritus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Pruritus generalised 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Pulmonary embolism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Pyrexia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Rash 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Diclofenac Rash erythematous 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Rash generalised 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Rectal haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Red blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Red blood cell sedimentation rate increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Renal failure 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Diclofenac Renal impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Renal tubular necrosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Respiratory depression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Restlessness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Rhabdomyolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Rheumatoid arthritis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Diclofenac Sedation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Shock haemorrhagic 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Skin discolouration 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Skin disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Skin exfoliation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Skin lesion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Stevens-Johnson syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Stomatitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Suicide attempt 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Swelling 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Swelling face 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Swollen tongue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Throat tightness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Thrombotic thrombocytopenic purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Tinnitus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Tongue oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Toxic epidermal necrolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Transaminases increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Tremor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Unresponsive to stimuli 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Upper gastrointestinal haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Urinary incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Urticaria 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Vertigo 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac Visual impairment 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diclofenac Wheezing 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diclofenac White blood cell count decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diclofenac White blood cell count increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac potassium Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac potassium Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac potassium Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diclofenac potassium Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac potassium Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac potassium Erythema multiforme 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac potassium Haematemesis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac potassium Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac potassium Hypotension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac potassium Infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac potassium Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diclofenac potassium Melaena 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac potassium Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac potassium Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac potassium Pyrexia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac potassium Rash 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Diclofenac potassium Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac potassium Seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac potassium Stomatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac potassium Tremor 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac potassium Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac potassium Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac sodium Abdominal pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diclofenac sodium Alopecia 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Diclofenac sodium Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diclofenac sodium Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac sodium Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Diclofenac sodium Anxiety 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Diclofenac sodium Arrhythmia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Diclofenac sodium Asthenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diclofenac sodium Asthma 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Diclofenac sodium Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac sodium Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac sodium Confusional state 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diclofenac sodium Constipation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac sodium Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diclofenac sodium Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diclofenac sodium Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diclofenac sodium Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diclofenac sodium Dry mouth 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac sodium Duodenal ulcer 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diclofenac sodium Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Diclofenac sodium Dyspnoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diclofenac sodium Gastric ulcer 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac sodium Gastrointestinal haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac sodium Haematemesis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diclofenac sodium Hallucination 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac sodium Headache 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Diclofenac sodium Hepatic enzyme increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diclofenac sodium Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac sodium Hypertension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diclofenac sodium Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac sodium Infection 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diclofenac sodium Insomnia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Diclofenac sodium Jaundice 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diclofenac sodium Malaise 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diclofenac sodium Melaena 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac sodium Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac sodium Nausea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diclofenac sodium Nervousness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diclofenac sodium Oedema 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diclofenac sodium Oliguria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac sodium Palpitations 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac sodium Pancreatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac sodium Paraesthesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac sodium Photosensitivity reaction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac sodium Pneumonia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Diclofenac sodium Pruritus 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Diclofenac sodium Purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac sodium Pyrexia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diclofenac sodium Rash 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Diclofenac sodium Rectal haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac sodium Renal failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac sodium Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac sodium Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac sodium Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac sodium Stomatitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diclofenac sodium Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac sodium Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac sodium Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diclofenac sodium Toxic epidermal necrolysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diclofenac sodium Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diclofenac sodium Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diclofenac sodium Vision blurred 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diclofenac sodium Vomiting 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Dicloxacillin Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dicloxacillin sodium Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dicyclomine hydrochloride Mydriasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Didanosine Anaemia 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Didanosine Aspartate aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Difluprednate Blindness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Difluprednate Eye pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Difluprednate Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Difluprednate Intraocular pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Difluprednate Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Difluprednate Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Digoxin Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Digoxin Acute respiratory failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Digoxin Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Atrial fibrillation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Digoxin Atrial flutter 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Digoxin Atrioventricular block 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Atrioventricular block complete 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Digoxin Atrioventricular block second degree 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Digoxin Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Digoxin Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Digoxin Cardiac failure congestive 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Digoxin Cardiac murmur 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Digoxin Cardiogenic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Digoxin Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Chronic kidney disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Circulatory collapse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Digoxin Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Digoxin Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Digoxin Confusional state 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Digoxin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Digoxin Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Depressed level of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Digoxin Diarrhoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Digoxin Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Drug interaction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Digoxin Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Dyspnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Digoxin Ejection fraction decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Electrocardiogram abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Encephalopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Extrasystoles 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Fatigue 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Digoxin Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Digoxin Hallucination, visual 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Heart rate increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Digoxin Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Hyperkalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Digoxin Hyperthyroidism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Digoxin Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Hypokalaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Digoxin Hyponatraemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Digoxin Hypoxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Digoxin Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Melaena 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Digoxin Metabolic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Digoxin Myoclonus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Digoxin Nausea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Digoxin Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Premature baby 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Digoxin Premature delivery 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Digoxin Pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Renal failure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Digoxin Renal impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Digoxin Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Digoxin Respiratory depression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Digoxin Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Digoxin Shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Digoxin Sinus tachycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Digoxin Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Sopor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Status epilepticus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Syncope 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Digoxin Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Thrombocytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Digoxin Torsade de pointes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Ventricular arrhythmia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Digoxin Ventricular extrasystoles 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Ventricular fibrillation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Digoxin Ventricular tachycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Digoxin Vision blurred 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Digoxin Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Digoxin Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Acidosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diltiazem Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Anuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Arrhythmia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diltiazem Arthropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diltiazem Asthenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Atrial fibrillation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Atrioventricular block 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diltiazem Atrioventricular block complete 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Atrioventricular block first degree 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diltiazem Atrioventricular block second degree 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Blood pressure increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diltiazem Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Bradycardia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Cardiac arrest 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Cardiogenic shock 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Coagulopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diltiazem Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diltiazem Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Contusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Cystitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diltiazem Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diltiazem Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diltiazem Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diltiazem Drug hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diltiazem Ear pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diltiazem Epistaxis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Face oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Heart rate decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diltiazem Hepatotoxicity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diltiazem Hyperglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diltiazem Hyperkalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Hypotension 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Hypoxia 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Diltiazem Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Influenza like illness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Lactic acidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Lymphadenopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Metabolic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diltiazem Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diltiazem Musculoskeletal stiffness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diltiazem Myopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Nausea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Oxygen saturation decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diltiazem Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Paraesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Peripheral ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Diltiazem Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Pulmonary oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diltiazem Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Renal failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diltiazem Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diltiazem Rhabdomyolysis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Diltiazem Seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diltiazem Shock 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Sinus bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Sinus tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diltiazem Somnolence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diltiazem Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diltiazem Syncope 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diltiazem Tachycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diltiazem Unresponsive to stimuli 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diltiazem Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diltiazem hydrochloride Atrioventricular block first degree 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diltiazem hydrochloride Bradycardia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Diltiazem hydrochloride Cardiac failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem hydrochloride Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem hydrochloride Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem hydrochloride Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diltiazem hydrochloride Hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem hydrochloride Myopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem hydrochloride Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem hydrochloride Paraesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem hydrochloride Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem hydrochloride Tinnitus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diltiazem hydrochloride Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Abasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Abdominal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Abdominal pain lower 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Abdominal tenderness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Abnormal faeces 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dimethyl fumarate Abscess 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Acute myocardial infarction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Acute respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Aggression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Agitation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dimethyl fumarate Alopecia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Amenorrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Amnesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Anal incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Angina pectoris 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Angiopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Aphasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Appendicitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Arrhythmia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Arthritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Arthropathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Ascites 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Aspiration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Asthma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Ataxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Atrial flutter 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Atrial septal defect 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Dimethyl fumarate Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Bacteraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Bacterial infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Balance disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Basal cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dimethyl fumarate Blindness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dimethyl fumarate Blister 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Blood cholesterol increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Blood count abnormal 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Blood creatine phosphokinase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dimethyl fumarate Blood disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Blood glucose decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Blood magnesium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Blood pressure abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Blood pressure decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Blood urine present 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Body temperature decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Bone disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Brain oedema 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dimethyl fumarate Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Burning sensation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Bursitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate C-reactive protein increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Cardiac arrest 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Cardiac disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Cardiac failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Cerebral haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Cerebral infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Cerebrovascular accident 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Chest discomfort 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Choking 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Cholecystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Chronic obstructive pulmonary disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Clostridium difficile colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Clostridium difficile infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Coagulopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Cognitive disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Colitis ischaemic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Colitis ulcerative 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dimethyl fumarate Colon cancer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Coma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Contusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Coordination abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Coronary artery disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Crying 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Cyst 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Cystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dimethyl fumarate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Decubitus ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Deep vein thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Dementia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Depressed level of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Depressed mood 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Depression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Dermatitis allergic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dimethyl fumarate Diabetic ketoacidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Diarrhoea haemorrhagic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dimethyl fumarate Diplopia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Diverticulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Drug eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Drug hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Drug intolerance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Dry eye 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Dry mouth 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Duodenal ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Dysaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Dysgeusia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Dyskinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Dyspepsia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Dysphonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Dysstasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Ear infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Ear pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Eating disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Emotional disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Emotional distress 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Encephalopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Epilepsy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dimethyl fumarate Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dimethyl fumarate Erythema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Eye disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Eye haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dimethyl fumarate Eye pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Eye pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Eye swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Faecaloma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Failure to thrive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Fear 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Feeding disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Feeling abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Feeling cold 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Feeling hot 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Feeling jittery 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Femur fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Fluid retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Flushing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Frequent bowel movements 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Fungal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Furuncle 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Gallbladder disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Gamma-glutamyltransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dimethyl fumarate Gastric disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Gastric haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Gastric ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Gastroenteritis viral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Gastrooesophageal reflux disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Generalised tonic-clonic seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Haematemesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Haematochezia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Haemoptysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Haemorrhagic stroke 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Haemorrhoids 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Hallucination, auditory 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Heart rate decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Heart rate irregular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Hemiparesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Hepatic function abnormal 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dimethyl fumarate Hepatic steatosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Hepatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dimethyl fumarate Hepatomegaly 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Hernia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Herpes zoster 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Hip fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Hot flush 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Hydronephrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Hypersomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Hypertensive crisis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Hyperthyroidism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Hypoacusis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Hypoaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Hypoaesthesia oral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Hypokinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Hypotonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Hypoxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Ill-defined disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Immune thrombocytopenic purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Influenza like illness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Intervertebral disc protrusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Intestinal perforation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Iron deficiency anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Irritability 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Irritable bowel syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Ischaemic stroke 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Joint swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Laboratory test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Leukocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Libido decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Limb discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Liver disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Liver function test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Liver function test increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Liver injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Local swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Localised infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Lower respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Lung disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Lymphadenopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Lymphoedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Lymphopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Malignant melanoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dimethyl fumarate Malnutrition 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Mania 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Memory impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Meningitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Menopausal symptoms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Menorrhagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Menstrual disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Mental disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Mental impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Metabolic acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Metastases to liver 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Middle insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Migraine 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Mobility decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Mood swings 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Motor dysfunction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Mouth ulceration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Muscle atrophy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Muscle spasms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Muscle tightness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Muscle twitching 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Musculoskeletal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Musculoskeletal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Musculoskeletal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Musculoskeletal stiffness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Myalgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Myocardial infarction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Neck pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dimethyl fumarate Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Nephropathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Nephropathy toxic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Nervous system disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Neuralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Neurological symptom 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Neuropathy peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Neutrophil count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dimethyl fumarate Night sweats 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Nightmare 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Obesity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Optic neuritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Oropharyngeal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Osteoarthritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Osteomyelitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Osteoporosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Oxygen saturation decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Pain in jaw 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Pain of skin 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Pallor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Pancytopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dimethyl fumarate Panic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Paraesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Parkinson's disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Pelvic pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Pericardial effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Peripheral coldness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Peritonitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Pharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Plasma cell myeloma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dimethyl fumarate Platelet count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Pleural effusion 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Dimethyl fumarate Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Pneumonia aspiration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Pneumonia bacterial 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Pneumonitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Pneumothorax 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Pollakiuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Poor quality sleep 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Dimethyl fumarate Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Prostate cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dimethyl fumarate Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Psychotic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Pulmonary embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Pulmonary mass 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Pyelonephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Rash erythematous 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Rash generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Rash macular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Rash vesicular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Renal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Renal failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Renal impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Renal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Respiratory arrest 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Respiratory disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Respiratory distress 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Respiratory failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Restless legs syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Restlessness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Retching 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Rhinitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dimethyl fumarate Rhinorrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Sciatica 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Seizure 0.0 0.0 1.0 0.0 0.0 0.0 1.0 Dimethyl fumarate Sensory disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Sepsis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Septic shock 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Sinusitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Skin burning sensation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Skin cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dimethyl fumarate Skin disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Skin irritation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Skin lesion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Skin mass 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Skin odour abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Skin ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Sleep apnoea syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Sleep disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Sluggishness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Small intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Sneezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Speech disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Spinal compression fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Spinal fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Splenomegaly 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Squamous cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dimethyl fumarate Staphylococcal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Stress 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Stress cardiomyopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Subarachnoid haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Subdural haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Suicidal ideation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dimethyl fumarate Suicide attempt 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Systemic lupus erythematosus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dimethyl fumarate Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Tendon rupture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Tendonitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Thinking abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Tongue disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Toxic skin eruption 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dimethyl fumarate Transient ischaemic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Treatment failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Troponin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Unresponsive to stimuli 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Upper limb fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Upper respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Urinary incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Urinary tract disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Urosepsis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Urticaria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Vaginal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Vaginal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Vasculitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Ventricular fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Ventricular tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Vision blurred 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Visual acuity reduced 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Visual impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Weight increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate Wheezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate White blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dimethyl fumarate White blood cell count increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dinoprostone Disseminated intravascular coagulation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dinoprostone Foetal death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Acute hepatic failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diphenhydramine Acute kidney injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Acute respiratory distress syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Aggression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diphenhydramine Agitation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Blood creatine phosphokinase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diphenhydramine Bradycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Brain oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Cardiogenic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Circulatory collapse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diphenhydramine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diphenhydramine Delirium 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Depressed level of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diphenhydramine Disseminated intravascular coagulation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Drug hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diphenhydramine Drug withdrawal syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diphenhydramine Electrocardiogram QT prolonged 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diphenhydramine Foetal death 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diphenhydramine Generalised tonic-clonic seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Hallucination, visual 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diphenhydramine Hepatotoxicity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diphenhydramine Hyperreflexia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diphenhydramine Hypoglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Hypoxia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Lactic acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Lethargy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Leukocytosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Mental status changes 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diphenhydramine Metabolic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Mydriasis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diphenhydramine Pneumonia aspiration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diphenhydramine Pulmonary congestion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Pyrexia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diphenhydramine Renal impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diphenhydramine Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Respiratory depression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Rhabdomyolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Salivary hypersecretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diphenhydramine Seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Sinus tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diphenhydramine Status epilepticus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Stupor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diphenhydramine Suicide attempt 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Diphenhydramine Tachycardia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Diphenhydramine Tachypnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diphenhydramine Torsade de pointes 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Tremor 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Unresponsive to stimuli 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diphenhydramine Ventricular arrhythmia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine Vomiting 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine hydrochloride Agitation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine hydrochloride Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Diphenhydramine hydrochloride Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine hydrochloride Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diphenhydramine hydrochloride Seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Diphenhydramine hydrochloride Tachycardia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Diphenhydramine hydrochloride Throat tightness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Diphenhydramine hydrochloride Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dipyridamole Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dipyridamole Atrioventricular block second degree 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dipyridamole Cardiac arrest 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dipyridamole Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dipyridamole Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dipyridamole Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dipyridamole Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dipyridamole Unevaluable event 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Disopyramide phosphate Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Disulfiram Alanine aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Disulfiram Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Disulfiram Drug-induced liver injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Disulfiram Hepatic failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Disulfiram Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Disulfiram Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Disulfiram Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Disulfiram Metabolic acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Disulfiram Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Disulfiram Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Disulfiram Peripheral sensory neuropathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Disulfiram Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Disulfiram Suicide attempt 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Divalproex sodium Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Divalproex sodium Aggression 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Divalproex sodium Agitation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Divalproex sodium Alopecia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Divalproex sodium Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Divalproex sodium Anxiety 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Divalproex sodium Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Divalproex sodium Chest pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Divalproex sodium Coma 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Divalproex sodium Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Divalproex sodium Coordination abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Divalproex sodium Deafness 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Divalproex sodium Dementia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Divalproex sodium Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Divalproex sodium Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Divalproex sodium Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Divalproex sodium Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Divalproex sodium Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Divalproex sodium Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Divalproex sodium Dyspnoea 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Divalproex sodium Emotional disorder 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Divalproex sodium Emotional distress 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Divalproex sodium Encephalopathy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Divalproex sodium Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Divalproex sodium Gait disturbance 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Divalproex sodium Hallucination 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Divalproex sodium Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Divalproex sodium Hepatotoxicity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Divalproex sodium Hyperglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Divalproex sodium Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Divalproex sodium Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Divalproex sodium Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Divalproex sodium Hypothermia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Divalproex sodium Inappropriate antidiuretic hormone secretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Divalproex sodium Injury 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Divalproex sodium Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Divalproex sodium Liver function test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Divalproex sodium Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Divalproex sodium Muscle spasms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Divalproex sodium Musculoskeletal stiffness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Divalproex sodium Nausea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Divalproex sodium Nervousness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Divalproex sodium Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Divalproex sodium Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Divalproex sodium Pain 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Divalproex sodium Pancreatitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Divalproex sodium Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Divalproex sodium Pancytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Divalproex sodium Paraesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Divalproex sodium Parkinsonism 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Divalproex sodium Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Divalproex sodium Psychotic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Divalproex sodium Pyrexia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Divalproex sodium Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Divalproex sodium Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Divalproex sodium Speech disorder 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Divalproex sodium Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Divalproex sodium Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Divalproex sodium Toxic epidermal necrolysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Divalproex sodium Transaminases increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Divalproex sodium Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Divalproex sodium Urinary incontinence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Divalproex sodium Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Divalproex sodium Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Divalproex sodium Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Divalproex sodium Weight increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Abdominal pain 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Abdominal pain lower 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Abdominal pain upper 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Acute myeloid leukaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Acute respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Ageusia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Agranulocytosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Alanine aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Docetaxel Altered state of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Anaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Docetaxel Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Ascites 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Aspartate aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Atelectasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Atrial fibrillation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Back pain 1.0 0.0 0.0 0.0 0.0 1.0 0.0 Docetaxel Balance disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Blister 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Blood alkaline phosphatase increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Blood bilirubin increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Blood creatine phosphokinase increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Blood pressure decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Blood pressure increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Body temperature increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Bone disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Docetaxel Bone marrow failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Bone pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Burning sensation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Candida infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Cardiac disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Cardiac failure congestive 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Cardiotoxicity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Cerebrovascular accident 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Chest discomfort 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Chills 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Chronic obstructive pulmonary disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Coagulopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Cognitive disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Cold sweat 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Colitis 1.0 1.0 1.0 1.0 0.0 0.0 0.0 Docetaxel Colitis ischaemic 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Congestive cardiomyopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Conjunctivitis 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Cough 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Deafness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Decreased appetite 1.0 1.0 1.0 1.0 0.0 0.0 0.0 Docetaxel Deep vein thrombosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Dehydration 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Docetaxel Depressed level of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Dermatitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Dermatitis bullous 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Diarrhoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Diarrhoea haemorrhagic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Docetaxel Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Disseminated intravascular coagulation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Drug interaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Dry eye 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Duodenal ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Dysgeusia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Dyspepsia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Dysphagia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Dyspnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Dyspnoea exertional 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Embolism 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Emotional distress 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Docetaxel Encephalopathy 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Enteritis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Enterocolitis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Epistaxis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Eye irritation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Faeces discoloured 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Fatigue 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Febrile neutropenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Feeling hot 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Fluid retention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Flushing 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Docetaxel Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Gastric haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Gastrointestinal disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Gastrooesophageal reflux disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Haemoglobin decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Haemoptysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Headache 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Docetaxel Heart rate decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Hepatobiliary disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Hepatocellular injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Hepatotoxicity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Hot flush 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Hyperglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Hyperkalaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Hypoacusis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Hypocalcaemia 1.0 0.0 1.0 1.0 0.0 0.0 0.0 Docetaxel Hyponatraemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Hypophagia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Docetaxel Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Hypoxia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Ileus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Inappropriate antidiuretic hormone secretion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Inflammation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Influenza like illness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Interstitial lung disease 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Intestinal obstruction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Lacrimation increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Large intestine perforation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Left ventricular dysfunction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Lethargy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Leukopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Liver disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Loss of consciousness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Lower respiratory tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Lung disorder 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Lung neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Docetaxel Lymphoedema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Malaise 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Docetaxel Melaena 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Menopausal symptoms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Mental disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Docetaxel Mental impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Docetaxel Metastases to liver 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Docetaxel Metastatic neoplasm 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Docetaxel Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Mouth ulceration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Mucosal inflammation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Muscular weakness 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Docetaxel Musculoskeletal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Musculoskeletal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Myalgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Myelodysplastic syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Myositis 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Docetaxel Nail disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Nausea 1.0 1.0 1.0 1.0 0.0 1.0 0.0 Docetaxel Neuralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Docetaxel Neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Neutrophil count decreased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Oedema peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Oesophagitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Oliguria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Oral candidiasis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Oropharyngeal pain 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Docetaxel Osteomyelitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Osteonecrosis of jaw 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Oxygen saturation decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Docetaxel Pain in extremity 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Docetaxel Pain of skin 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Palpitations 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Pericardial effusion 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Peripheral sensory neuropathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Pharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Photosensitivity reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Platelet count decreased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Pleural effusion 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Pneumonia 1.0 1.0 1.0 1.0 0.0 0.0 0.0 Docetaxel Pneumonia aspiration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Pneumonitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Pneumothorax 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Polyneuropathy 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Presyncope 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Docetaxel Productive cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Prostate cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Docetaxel Pruritus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Pulmonary embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Pulmonary hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Pyrexia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Rales 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Rash 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Rash generalised 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Rash maculo-papular 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Rectal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Renal impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Renal tubular necrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Respiratory disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Respiratory distress 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Rhabdomyolysis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Rhinorrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Sepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Septic shock 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Sinus tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Skin discolouration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Skin disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Skin exfoliation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Skin hyperpigmentation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Docetaxel Skin reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Docetaxel Somnolence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Speech disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Docetaxel Stevens-Johnson syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Stomatitis 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Docetaxel Supraventricular tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Docetaxel Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Toxic epidermal necrolysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Toxic skin eruption 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Tremor 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Vertigo 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Vision blurred 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Vomiting 1.0 1.0 1.0 1.0 0.0 0.0 0.0 Docetaxel Weight decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Docetaxel Wheezing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Docetaxel White blood cell count decreased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Angina pectoris 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Dofetilide Cardiac disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dofetilide Cardiac failure congestive 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dofetilide Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Chronic obstructive pulmonary disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dofetilide Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dofetilide Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Drug intolerance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dofetilide Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Feeling abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Heart rate decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Heart rate irregular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Hernia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Migraine 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Paraesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dofetilide Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Renal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dofetilide Respiratory failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Sepsis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Suicide attempt 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Torsade de pointes 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Dofetilide Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dofetilide Ventricular extrasystoles 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dofetilide Ventricular fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dofetilide Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Dofetilide Weight increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dolutegravir sodium Alanine aminotransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dolutegravir sodium Asthenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dolutegravir sodium Blood creatinine increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dolutegravir sodium Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dolutegravir sodium Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dolutegravir sodium Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dolutegravir sodium Hyperglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dolutegravir sodium Insomnia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dolutegravir sodium Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dolutegravir sodium Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dolutegravir sodium Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dolutegravir sodium Rash 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dolutegravir sodium Renal impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dolutegravir sodium Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Donepezil Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Donepezil Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Abnormal dreams 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Donepezil Acute kidney injury 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Donepezil Affect lability 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Aggression 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Agitation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Donepezil Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Anal incontinence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Donepezil Anger 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Donepezil Angioedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Donepezil Aphasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Donepezil Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Donepezil Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Atrioventricular block 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Atrioventricular block complete 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Donepezil Atrioventricular block first degree 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Donepezil Balance disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Donepezil Blood creatine phosphokinase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Blood pressure decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Cardiac arrest 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Donepezil Cardio-respiratory arrest 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Donepezil Cerebral haemorrhage 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Donepezil Cerebrovascular accident 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Donepezil Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Circulatory collapse 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Donepezil Cognitive disorder 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Donepezil Cold sweat 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Confusional state 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Donepezil Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Donepezil Contusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Donepezil Crying 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Donepezil Decreased appetite 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Donepezil Deep vein thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Donepezil Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Donepezil Delirium 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Donepezil Depressed level of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Donepezil Diarrhoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Donepezil Discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Disorientation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Donepezil Dizziness 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Donepezil Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Donepezil Duodenal ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Dyskinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Donepezil Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Dysphonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Donepezil Electrocardiogram QT prolonged 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Donepezil Epilepsy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Donepezil Extrapyramidal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Flatulence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Gastric ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Gastritis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Donepezil Gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Donepezil Generalised tonic-clonic seizure 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Donepezil Haematemesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Haematoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Donepezil Haemodynamic instability 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Hallucination 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Donepezil Hallucination, visual 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Donepezil Heart rate decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Hepatic function abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Donepezil Hepatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Donepezil Hiccups 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Hyperhidrosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Donepezil Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Hypertonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Donepezil Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Hypophagia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Donepezil Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Donepezil Ileus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Inappropriate antidiuretic hormone secretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Injury 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Donepezil Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Donepezil Irritability 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Donepezil Jaundice 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Donepezil Joint swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Liver function test abnormal 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Donepezil Loss of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Donepezil Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Donepezil Mania 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Melaena 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Mental disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Donepezil Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Miosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Mobility decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Donepezil Muscle atrophy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Donepezil Muscle contractions involuntary 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Muscle rigidity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Donepezil Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Myoclonus 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Donepezil Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Neuroleptic malignant syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Donepezil Nightmare 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Donepezil Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Oesophagitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Donepezil Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Donepezil Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Panic attack 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Donepezil Peritonitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Donepezil Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Pollakiuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Donepezil Psychomotor hyperactivity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Donepezil Psychotic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Rash pruritic 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Donepezil Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Donepezil Renal impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Restlessness 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Retinal detachment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Rhinorrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Seizure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Donepezil Sepsis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Shock haemorrhagic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Sinus bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Donepezil Skin discolouration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Sleep disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Donepezil Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Donepezil Sopor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Speech disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Donepezil Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Donepezil Suicidal ideation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Donepezil Suicide attempt 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Syncope 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Donepezil Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Torsade de pointes 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Donepezil Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Unresponsive to stimuli 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Donepezil Upper gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil Urinary incontinence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Donepezil Urinary retention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Donepezil Ventricular tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Donepezil Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Aggression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Anal incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Cerebral infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Confusional state 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Donepezil hydrochloride Decreased appetite 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Dehydration 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Diarrhoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Duodenal ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Gastric ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Generalised tonic-clonic seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Hallucination 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Neuroleptic malignant syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Restlessness 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Urinary incontinence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Donepezil hydrochloride Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Donepezil hydrochloride Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Dorzolamide hydrochloride Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dorzolamide hydrochloride Dyspnoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dorzolamide hydrochloride Eye irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dorzolamide hydrochloride Eye pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dorzolamide hydrochloride Hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxazosin mesylate Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxazosin mesylate Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Doxazosin mesylate Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxazosin mesylate Constipation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxazosin mesylate Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxazosin mesylate Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxazosin mesylate Dyspnoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxazosin mesylate Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxazosin mesylate Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxazosin mesylate Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxazosin mesylate Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxazosin mesylate Muscular weakness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxazosin mesylate Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxazosin mesylate Pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxazosin mesylate Palpitations 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxazosin mesylate Pollakiuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxazosin mesylate Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxazosin mesylate Syncope 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Doxazosin mesylate Tachycardia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxazosin mesylate Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxazosin mesylate Tremor 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxazosin mesylate Urinary incontinence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxepin Acute kidney injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxepin Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxepin Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxepin Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxepin Cardiac arrest 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxepin Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxepin Coma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxepin Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxepin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxepin Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxepin Depressed level of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxepin Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxepin Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxepin Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxepin Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxepin Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxepin Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxepin Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxepin Pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxepin Respiratory depression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxepin Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxepin Suicidal ideation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxepin Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxepin hydrochloride Hypotension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Abdominal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Abdominal pain lower 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Abdominal pain upper 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Abscess 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Acute hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Acute kidney injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Acute myeloid leukaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Acute myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Acute pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Acute respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Agranulocytosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Alopecia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Anaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Angina pectoris 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Anxiety 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Asthenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Atrial fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Bacteraemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Blood bilirubin increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Blood creatinine increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Blood uric acid increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Bone marrow failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Bone pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Brain oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxorubicin Candida infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Cardiac disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Cardiac failure acute 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Cardiac failure congestive 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Cardiogenic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Cardiomyopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Cardiopulmonary failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Cardiotoxicity 1.0 1.0 0.0 0.0 1.0 0.0 0.0 Doxorubicin Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Chest pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Chills 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Chronic kidney disease 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Cognitive disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxorubicin Colitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Confusional state 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Congestive cardiomyopathy 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Doxorubicin Constipation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Cough 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxorubicin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Decreased appetite 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Deep vein thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Dehydration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Depression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Dermatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxorubicin Diarrhoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Disease recurrence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Disseminated intravascular coagulation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxorubicin Dyskinesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Dyspepsia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Dysphagia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Dyspnoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Dyspnoea exertional 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Ejection fraction decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Encephalopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Enterocolitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Epilepsy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Epistaxis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Extravasation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxorubicin Fatigue 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Febrile neutropenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Feeling hot 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Fungal infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Gastric ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Gastrointestinal disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Haematemesis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Haematuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Haemoglobin decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Headache 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Hepatic function abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Hepatic necrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Hepatitis 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxorubicin Hepatomegaly 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Hepatotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxorubicin Herpes simplex 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Herpes zoster 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Hyperbilirubinaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Hypercalcaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Hyperglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Hypokalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Hyponatraemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Hypothyroidism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxorubicin Hypoxia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Influenza 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Insomnia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Interstitial lung disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxorubicin Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Intestinal perforation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Ischaemic stroke 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Jaundice 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Left ventricular dysfunction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Leukopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Liver disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxorubicin Lung disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Lung infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Lung infiltration 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxorubicin Lymphadenopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Lymphocyte count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Lymphopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Malaise 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Malignant neoplasm progression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Melaena 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Metastases to liver 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxorubicin Metastases to lung 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Mitral valve incompetence 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Mucosal inflammation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Myalgia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Myelodysplastic syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Myocarditis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Nausea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Neoplasm 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxorubicin Neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Nephropathy toxic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxorubicin Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxorubicin Neurotoxicity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Neutrophil count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Oedema peripheral 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Oliguria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Oropharyngeal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Osteonecrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxorubicin Osteoporosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Pain in extremity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Peripheral sensory neuropathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Plasma cell myeloma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Platelet count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Pleural effusion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Pneumocystis jirovecii pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Pneumonitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Pneumothorax 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Polyneuropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxorubicin Premature baby 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxorubicin Productive cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Pulmonary alveolar haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Pulmonary embolism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Pulmonary fibrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Pyrexia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Respiratory disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Respiratory distress 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Respiratory tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Sinus tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Sinusitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Skin infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Staphylococcal infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Stomatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Supraventricular tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Tachypnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Treatment failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Tumour lysis syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Upper respiratory tract infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Urinary tract infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Ventricular arrhythmia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Ventricular fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin Ventricular tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin Vomiting 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin White blood cell count increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Acute myeloid leukaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Alanine aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxorubicin hydrochloride Anaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Asthenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Back pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Cardiomyopathy 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Doxorubicin hydrochloride Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Chills 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Congestive cardiomyopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Constipation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Decreased appetite 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Deep vein thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Depression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Diarrhoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Dry skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxorubicin hydrochloride Dyspepsia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Dysphagia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Dyspnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Headache 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Hepatitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Herpes simplex 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Herpes zoster 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Hyperbilirubinaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Hypercalcaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Hypokalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Hyponatraemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Hypotension 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Ileus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Neuropathy peripheral 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxorubicin hydrochloride Neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Paraesthesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Pharyngitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Pulmonary embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Rhinitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Sinusitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Skin discolouration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Stomatitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Thrombosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Urinary tract infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxorubicin hydrochloride Vomiting 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxycycline Abdominal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Doxycycline Abdominal distension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline Abdominal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline Abdominal pain upper 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline Acute kidney injury 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Doxycycline Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxycycline Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxycycline Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline Blood pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxycycline Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxycycline Bronchospasm 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxycycline Chest pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline Clostridium difficile infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxycycline Confusional state 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Doxycycline Conjunctivitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxycycline Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxycycline Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline Discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxycycline Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Doxycycline Drug eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxycycline Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxycycline Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxycycline Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Doxycycline Dysphagia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxycycline Dyspnoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Doxycycline Ear infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxycycline Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxycycline Feeling abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxycycline Flushing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxycycline Haemolytic anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxycycline Hallucination 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxycycline Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline Hepatitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline Hypertension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxycycline Inflammation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline Insomnia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Doxycycline Intracranial pressure increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline Leukopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxycycline Liver function test abnormal 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline Malaise 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Doxycycline Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxycycline Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline Nasopharyngitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxycycline Nausea 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Doxycycline Neck pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxycycline Oedema peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline Oesophageal ulcer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxycycline Oral pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxycycline Pancreatitis acute 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Doxycycline Panic attack 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Doxycycline Photosensitivity reaction 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Doxycycline Platelet count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxycycline Rash 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxycycline Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxycycline Sinusitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxycycline Somnolence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline Stevens-Johnson syndrome 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Doxycycline Swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxycycline Thrombocytopenia 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline Thrombocytopenic purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxycycline Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline Tongue discolouration 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline Tooth disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Doxycycline Toxic epidermal necrolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxycycline Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Doxycycline Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline Vomiting 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline hyclate Abdominal pain upper 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline hyclate Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline hyclate Decreased appetite 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Doxycycline hyclate Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline hyclate Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline hyclate Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline hyclate Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline hyclate Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Doxycycline hyclate Thrombocytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxycycline hyclate Vomiting 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Doxylamine Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Doxylamine Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dronabinol Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dronabinol Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dronabinol Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dronabinol Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dronedarone Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dronedarone Acute kidney injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dronedarone Atrial fibrillation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dronedarone Cardiac arrest 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dronedarone Cardiac disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dronedarone Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dronedarone Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dronedarone Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dronedarone Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dronedarone Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dronedarone Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dronedarone Electrocardiogram QT prolonged 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dronedarone Epistaxis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dronedarone Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dronedarone Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dronedarone Jaundice 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dronedarone Liver function test abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dronedarone Nervousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dronedarone Oxygen saturation decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dronedarone Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dronedarone Pulmonary fibrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dronedarone Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dronedarone Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dronedarone Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dronedarone Vomiting 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Droperidol Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Droperidol Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Droxidopa Abasia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Droxidopa Acute kidney injury 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Acute respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Droxidopa Aggression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Angina pectoris 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Droxidopa Aphasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Droxidopa Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Blood pressure abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Blood pressure decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Droxidopa Cardiac disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Droxidopa Cardiac failure congestive 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Droxidopa Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Droxidopa Cerebrovascular accident 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Choking 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Droxidopa Chronic obstructive pulmonary disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Droxidopa Clostridium difficile infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Coma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Droxidopa Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Cystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Droxidopa Decubitus ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Deep vein thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Dementia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Droxidopa Diabetic ketoacidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Droxidopa Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Droxidopa Drug hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Dysphagia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Failure to thrive 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Droxidopa Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Droxidopa Feeling hot 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Droxidopa Fluid retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Droxidopa Gastrooesophageal reflux disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Haemorrhagic stroke 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Droxidopa Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Droxidopa Hip fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Hypersomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Droxidopa Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Hypoxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Influenza like illness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Irritability 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Droxidopa Localised infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Loss of consciousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Droxidopa Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Droxidopa Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Mental disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Mental impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Droxidopa Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Droxidopa Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Droxidopa Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Droxidopa Nasopharyngitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Droxidopa Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Droxidopa Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Oxygen saturation decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Parkinson's disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Droxidopa Pleural effusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Pneumonia aspiration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Presyncope 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Droxidopa Pulmonary embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Renal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Droxidopa Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Droxidopa Respiratory disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Droxidopa Sepsis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Septic shock 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Spinal fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Staphylococcal infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Stress cardiomyopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Subdural haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Suicidal ideation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Droxidopa Supraventricular tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Transient ischaemic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Unevaluable event 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Unresponsive to stimuli 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Urosepsis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Droxidopa Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Droxidopa Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duloxetine Abdominal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Abdominal distension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Abdominal pain 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Duloxetine Abdominal pain upper 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Abnormal dreams 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine Acute kidney injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Affect lability 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Aggression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Agitation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine Amnesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Duloxetine Anger 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Apathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Ataxia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Atrial fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Atrial septal defect 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Duloxetine Balance disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Blood creatine phosphokinase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Blood creatinine increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Blood pressure increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Burning sensation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Chest pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Chills 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Cognitive disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Confusional state 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Contusion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duloxetine Crying 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Decreased appetite 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Dehydration 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Delirium 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Delusion 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Depressed level of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Depressed mood 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Dermatitis allergic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duloxetine Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Disorientation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Duloxetine Disturbance in attention 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Drug abuse 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Drug dependence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine Drug interaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine Drug withdrawal syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Dyskinesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Dysphonia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine Dysphoria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duloxetine Dyspnoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Dyspnoea exertional 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duloxetine Dystonia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Dysuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Emotional disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Emotional distress 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Encephalopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duloxetine Epistaxis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Extrapyramidal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duloxetine Extrasystoles 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duloxetine Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Fear 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine Feeding disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Feeling abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Gait disturbance 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Gastrointestinal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Generalised tonic-clonic seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Haematemesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duloxetine Haematochezia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Duloxetine Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duloxetine Hallucination 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Hallucination, visual 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Heart rate increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Hepatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duloxetine Hot flush 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Hyperreflexia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Hypersomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Hypertension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Hyperthermia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Hyperventilation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Hypoglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Hypokalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Duloxetine Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Hypothermia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duloxetine Hypotonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Inappropriate antidiuretic hormone secretion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Influenza like illness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Insomnia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Intentional self-injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duloxetine Interstitial lung disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine Irritability 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duloxetine Lethargy 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Limb discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine Liver disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duloxetine Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Loss of libido 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine Malaise 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Mania 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Mental impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine Metabolic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Mood swings 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Muscle spasms 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Muscle twitching 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Musculoskeletal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duloxetine Musculoskeletal stiffness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Mydriasis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Myoclonus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Neck pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine Nephrolithiasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine Nervousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Night sweats 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Nightmare 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Duloxetine Nystagmus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duloxetine Oropharyngeal pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Oxygen saturation decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Pallor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duloxetine Palpitations 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Pancreatitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Panic attack 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Paraesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Paranoia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Peripheral swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine Personality change 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Pneumonia 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Duloxetine Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Poor quality sleep 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Duloxetine Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Psychomotor hyperactivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Pulmonary embolism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine Pyrexia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Respiratory distress 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duloxetine Respiratory failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duloxetine Restless legs syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Restlessness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Rhabdomyolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Rheumatoid arthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine Sedation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine Seizure 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Serotonin syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Sinus tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Duloxetine Sleep disorder 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Somnolence 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Duloxetine Sopor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duloxetine Suicidal ideation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Swollen tongue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duloxetine Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Tachypnoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Tardive dyskinesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Thinking abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Treatment failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine Tremor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Unresponsive to stimuli 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Urinary retention 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine Ventricular fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine Ventricular tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duloxetine Vertigo 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Vision blurred 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Vomiting 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine Weight decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine White blood cell count increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duloxetine Withdrawal syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Abdominal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Abdominal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Abdominal pain upper 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Abnormal dreams 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Affect lability 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Aggression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Agitation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Alanine aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine hydrochloride Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Duloxetine hydrochloride Anaphylactic reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Anger 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Duloxetine hydrochloride Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Apathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Arthralgia 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Duloxetine hydrochloride Aspartate aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine hydrochloride Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Blood cholesterol increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Blood creatine phosphokinase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine hydrochloride Blood glucose increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine hydrochloride Blood pressure increased 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Duloxetine hydrochloride Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Duloxetine hydrochloride Chest pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Chills 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Cold sweat 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Duloxetine hydrochloride Confusional state 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Coordination abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Cough 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Decreased appetite 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Dehydration 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine hydrochloride Diabetes mellitus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine hydrochloride Diarrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Diplopia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine hydrochloride Disorientation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Duloxetine hydrochloride Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Drug withdrawal syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Dry eye 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Dysarthria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine hydrochloride Dysgeusia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Dyskinesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Dysphagia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Dysuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Ecchymosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duloxetine hydrochloride Erectile dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine hydrochloride Extrapyramidal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duloxetine hydrochloride Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Feeding disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Feeling abnormal 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Duloxetine hydrochloride Feeling cold 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Feeling jittery 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Gastrointestinal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Haematochezia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Hallucination 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Duloxetine hydrochloride Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Hepatic failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine hydrochloride Hepatic steatosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Duloxetine hydrochloride Hot flush 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Duloxetine hydrochloride Hyperhidrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine hydrochloride Hypersomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Hypertension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Hypoaesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duloxetine hydrochloride Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Duloxetine hydrochloride Inappropriate antidiuretic hormone secretion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Duloxetine hydrochloride Increased appetite 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine hydrochloride Influenza 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Influenza like illness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Irritability 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Irritable bowel syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Jaundice 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine hydrochloride Lethargy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Libido decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine hydrochloride Loss of libido 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Malaise 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Malnutrition 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duloxetine hydrochloride Mania 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Melaena 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duloxetine hydrochloride Mental disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Migraine 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Duloxetine hydrochloride Mood swings 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Muscle spasms 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Muscle twitching 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Musculoskeletal stiffness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Myalgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Nasopharyngitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Neck pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Nervous system disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Nervousness 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Duloxetine hydrochloride Night sweats 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Nightmare 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Oedema peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Orthostatic hypotension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Osteoarthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Pain 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Duloxetine hydrochloride Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Duloxetine hydrochloride Palpitations 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Paraesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Paraesthesia oral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Peripheral coldness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Pharyngeal oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine hydrochloride Photosensitivity reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Pollakiuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Polyuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duloxetine hydrochloride Poor quality sleep 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Pruritus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Rash 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Duloxetine hydrochloride Renal failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine hydrochloride Renal impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Restless legs syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Restlessness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Duloxetine hydrochloride Seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Serotonin syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine hydrochloride Sexual dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine hydrochloride Sleep disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Sluggishness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Somnolence 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Duloxetine hydrochloride Stomatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Suicidal ideation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Syncope 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duloxetine hydrochloride Tension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Tinnitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Tremor 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Duloxetine hydrochloride Urinary retention 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Urinary tract infection 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Duloxetine hydrochloride Urticaria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Vertigo 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Vision blurred 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Duloxetine hydrochloride Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Duloxetine hydrochloride Vomiting 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Duloxetine hydrochloride Weight decreased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Duloxetine hydrochloride Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Dutasteride Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dutasteride Arrhythmia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dutasteride Breast cancer 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dutasteride Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Dutasteride Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dutasteride Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dutasteride Erectile dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dutasteride Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dutasteride Gynaecomastia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dutasteride Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dutasteride Jaundice cholestatic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dutasteride Libido decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dutasteride Loss of libido 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dutasteride Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Dutasteride Pollakiuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dutasteride Prostate cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dutasteride Sopor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Dutasteride Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Dutasteride Urinary retention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Dutasteride Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Duvelisib Abdominal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duvelisib Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duvelisib Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duvelisib Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duvelisib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Duvelisib Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duvelisib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Duvelisib Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duvelisib Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duvelisib Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duvelisib Malignant neoplasm progression 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Duvelisib Nausea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Duvelisib Neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duvelisib Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Duvelisib Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duvelisib Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duvelisib Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Duvelisib Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duvelisib Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duvelisib Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Duvelisib White blood cell count increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ecallantide Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ecallantide Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ecallantide Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ecallantide Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ecallantide Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ecallantide Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Edaravone Aphasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Edaravone Asthenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Edaravone Cerebral infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Edaravone Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Edaravone Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Edaravone Deep vein thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Edaravone Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Edaravone Dyspnoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Edaravone Feeling abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Edaravone Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Edaravone Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Edaravone Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Edaravone Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Edaravone Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Edaravone Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Edaravone Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Edoxaban Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Edoxaban Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Edoxaban Cardiac failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Edoxaban Haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Edoxaban tosylate Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Edoxaban tosylate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Edoxaban tosylate Epistaxis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Edoxaban tosylate Gastric haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Edoxaban tosylate Gastrointestinal haemorrhage 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Edoxaban tosylate Haematuria 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Edoxaban tosylate Haemoglobin decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Edoxaban tosylate Haemorrhage 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Edoxaban tosylate Haemorrhage intracranial 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Edoxaban tosylate Haemorrhagic stroke 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Edoxaban tosylate Interstitial lung disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Edoxaban tosylate Ischaemic stroke 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Edoxaban tosylate Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Edoxaban tosylate Subarachnoid haemorrhage 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Efavirenz Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Efavirenz Abortion spontaneous 0.0 0.0 0.0 0.0 1.0 0.0 1.0 Efavirenz Acute hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Efavirenz Anaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Efavirenz Ataxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Efavirenz Confusional state 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Efavirenz Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Efavirenz Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Efavirenz Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Efavirenz Depression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Efavirenz Diarrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Efavirenz Diplopia 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Efavirenz Disturbance in attention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Efavirenz Drug resistance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Efavirenz Drug-induced liver injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Efavirenz Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Efavirenz Foetal death 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Efavirenz Generalised tonic-clonic seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Efavirenz Gynaecomastia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Efavirenz Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Efavirenz Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Efavirenz Hepatotoxicity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Efavirenz Hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Efavirenz Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Efavirenz Jaundice 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Efavirenz Lactic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Efavirenz Liver disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Efavirenz Metabolic disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Efavirenz Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Efavirenz Nephropathy toxic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Efavirenz Nervous system disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Efavirenz Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Efavirenz Neurotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Efavirenz Nightmare 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Efavirenz Oral candidiasis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Efavirenz Pancytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Efavirenz Photosensitivity reaction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Efavirenz Platelet count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Efavirenz Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Efavirenz Pregnancy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Efavirenz Premature baby 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Efavirenz Premature delivery 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Efavirenz Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Efavirenz Rash maculo-papular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Efavirenz Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Efavirenz Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Efavirenz Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Efavirenz Sleep disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Efavirenz Suicidal ideation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Efavirenz Treatment failure 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Efavirenz Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eletriptan hydrobromide Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Eletriptan hydrobromide Back pain 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Eletriptan hydrobromide Cerebrovascular disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Eletriptan hydrobromide Confusional state 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Eletriptan hydrobromide Diplopia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Eletriptan hydrobromide Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Eletriptan hydrobromide Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Eletriptan hydrobromide Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Eletriptan hydrobromide Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Eletriptan hydrobromide Vomiting 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Eletriptan hydrobromide Weight decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Eltrombopag Abdominal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Abdominal distension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Abdominal pain upper 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Eltrombopag Acute kidney injury 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Eltrombopag Acute myeloid leukaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Acute myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Alanine aminotransferase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Alopecia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Eltrombopag Amnesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Anxiety 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Aplastic anaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Arthralgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Eltrombopag Aspartate aminotransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Asthenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Back pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Balance disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Eltrombopag Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Eltrombopag Blood bilirubin increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Blood disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Blood glucose increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Blood pressure decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Blood pressure increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Blood triglycerides increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Bone marrow failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Bone pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Eltrombopag Bronchitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Cataract 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Cerebral haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Cerebral infarction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Eltrombopag Cerebrovascular accident 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Chest pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Confusional state 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Constipation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Contusion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Cough 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Decreased appetite 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Deep vein thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Depression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Diarrhoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Dizziness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Drug hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Drug intolerance 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Dyspepsia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Dyspnoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Epistaxis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Erythema 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Febrile neutropenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Feeding disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Feeling abnormal 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Gait disturbance 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Eltrombopag Gastrointestinal disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Gastrointestinal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Gingival bleeding 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Haematochezia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Haemoglobin decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Haemoptysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Haemorrhage intracranial 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Headache 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Hepatic enzyme increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Hepatotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Eltrombopag Hyperbilirubinaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Eltrombopag Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Hypoacusis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Hypoaesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Eltrombopag Hypotension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Ill-defined disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Immune thrombocytopenic purpura 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Infection 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Influenza 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Insomnia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Eltrombopag Intervertebral disc protrusion 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Eltrombopag Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Jaundice 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Joint swelling 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Eltrombopag Leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Limb discomfort 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Eltrombopag Liver disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Liver function test abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Eltrombopag Loss of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Lymphoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Malaise 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Memory impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Migraine 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Eltrombopag Muscle spasms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Muscular weakness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Eltrombopag Musculoskeletal chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Musculoskeletal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Myelodysplastic syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Nasopharyngitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Nausea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Neck pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Eltrombopag Neutrophil count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Oedema peripheral 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Oropharyngeal pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Eltrombopag Pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Pain in extremity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Pallor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Paraesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Eltrombopag Peripheral swelling 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Eltrombopag Petechiae 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Plasma cell myeloma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Platelet count decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Premature baby 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Eltrombopag Pruritus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Eltrombopag Pulmonary embolism 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Rectal haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Red blood cell count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Renal disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Seizure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Sepsis 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Eltrombopag Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Sinusitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Skin discolouration 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Eltrombopag Skin exfoliation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Eltrombopag Somnolence 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Eltrombopag Speech disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Splenomegaly 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Stress 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Swelling 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Swelling face 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Eltrombopag Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Transaminases increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Tremor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Urinary tract infection 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Urticaria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Viral infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Vision blurred 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag Visual impairment 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag Weight decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag White blood cell count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag White blood cell count increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag olamine Alopecia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Eltrombopag olamine Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag olamine Asthenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag olamine Back pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag olamine Cataract 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Eltrombopag olamine Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag olamine Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag olamine Decreased appetite 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag olamine Diarrhoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag olamine Fatigue 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag olamine Haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag olamine Headache 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag olamine Influenza 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Eltrombopag olamine Insomnia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Eltrombopag olamine Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag olamine Oedema peripheral 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag olamine Oropharyngeal pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Eltrombopag olamine Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Eltrombopag olamine Pruritus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Eltrombopag olamine Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag olamine Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eltrombopag olamine Urinary tract infection 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eltrombopag olamine Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eluxadoline Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eluxadoline Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eluxadoline Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eluxadoline Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eluxadoline Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eluxadoline Gastrooesophageal reflux disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eluxadoline Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eluxadoline Liver function test increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eluxadoline Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eluxadoline Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eluxadoline Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eluxadoline Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eluxadoline Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Abdominal discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Empagliflozin Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Abdominal pain upper 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Abscess 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Empagliflozin Acidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Acute kidney injury 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Empagliflozin Acute myocardial infarction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Empagliflozin Altered state of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Anaemia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Empagliflozin Angina pectoris 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Anuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Arrhythmia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Empagliflozin Asthenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Atrial fibrillation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Back pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Blindness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Empagliflozin Blood cholesterol increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Empagliflozin Blood creatinine increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Blood glucose decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Blood glucose increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Blood potassium increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Blood pressure decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Blood urea increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Brain oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Empagliflozin Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin C-reactive protein increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Empagliflozin Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Empagliflozin Cardiac disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Cardiac failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Empagliflozin Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Cerebral infarction 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Empagliflozin Chest discomfort 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Chest pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Chills 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Cholecystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Cholecystitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Chronic kidney disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Empagliflozin Confusional state 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Empagliflozin Constipation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Empagliflozin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Empagliflozin Decreased appetite 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Delirium 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Empagliflozin Dementia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Empagliflozin Depressed level of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Depression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Empagliflozin Dermatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Diabetes mellitus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Diabetic ketoacidosis 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Empagliflozin Diarrhoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Disturbance in attention 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Empagliflozin Dizziness 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Empagliflozin Dry mouth 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Empagliflozin Dyspnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Dyspnoea exertional 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Dysuria 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Empagliflozin Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Erythema 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Empagliflozin Fatigue 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Empagliflozin Femur fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Flank pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Fungal infection 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Empagliflozin Gastric disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Gastroenteritis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Glycosuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Headache 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Empagliflozin Hepatic cirrhosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Empagliflozin Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Empagliflozin Hepatic function abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Hypercalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Hyperglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Hyperkalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Hypernatraemia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Empagliflozin Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Empagliflozin Hyperventilation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Empagliflozin Hypoglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Hypophagia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Hypotension 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Empagliflozin Hypovolaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Ill-defined disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Infarction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Empagliflozin Infection 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Influenza like illness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Empagliflozin Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Lactic acidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Leukocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Empagliflozin Localised infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Loss of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Empagliflozin Malaise 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Metabolic acidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Micturition urgency 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Empagliflozin Muscular weakness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Empagliflozin Myalgia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Empagliflozin Myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Empagliflozin Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Nausea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Empagliflozin Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Neuropathy peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Nocturia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Empagliflozin Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Osteomyelitis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Empagliflozin Oxygen saturation decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Empagliflozin Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Empagliflozin Palpitations 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Empagliflozin Pancreatic carcinoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Empagliflozin Pancreatitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Pancreatitis acute 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Peripheral ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Peripheral swelling 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Peripheral vascular disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Empagliflozin Pleural effusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Empagliflozin Pneumonia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Pollakiuria 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Empagliflozin Polyuria 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Empagliflozin Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Empagliflozin Pulmonary embolism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Empagliflozin Pulmonary oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Empagliflozin Pyelonephritis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Rash 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Empagliflozin Renal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Renal failure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Renal impairment 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Empagliflozin Renal tubular necrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Empagliflozin Respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Sepsis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Septic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Empagliflozin Skin ulcer 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Empagliflozin Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Empagliflozin Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Empagliflozin Suicidal ideation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Empagliflozin Swollen tongue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Empagliflozin Tachypnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Thirst 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Empagliflozin Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Upper respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Urinary incontinence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Empagliflozin Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Urinary tract infection 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Empagliflozin Urosepsis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Empagliflozin Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Empagliflozin Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Weight decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin Weight increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Empagliflozin White blood cell count increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Emtricitabine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Emtricitabine Renal failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enalapril Abdominal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enalapril Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enalapril Anaphylactic reaction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enalapril Angioedema 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Enalapril Asthenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Enalapril Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enalapril Blood pressure decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enalapril Blood pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enalapril Cardiac failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Enalapril Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enalapril Coronary artery disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enalapril Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Enalapril Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enalapril Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enalapril Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enalapril Dizziness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Enalapril Dyspnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Enalapril Erythema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enalapril Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enalapril Hyperkalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Enalapril Hypertensive crisis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enalapril Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Enalapril Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Enalapril Nausea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Enalapril Pancreatitis acute 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Enalapril Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enalapril Respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Enalapril Swollen tongue 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Enalapril Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enalapril Tongue oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Enalapril Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Enalapril maleate Angioedema 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Enalapril maleate Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enalapril maleate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enalapril maleate Drug interaction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Enalapril maleate Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enalapril maleate Hyperkalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enalapril maleate Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enalapril maleate Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enalapril maleate Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enalapril maleate Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enalapril maleate Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enalapril maleate Toxic epidermal necrolysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enalapril maleate Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enalapril maleate Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enasidenib Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enasidenib Acute myeloid leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enasidenib Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enasidenib Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enasidenib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enasidenib Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enasidenib Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enasidenib Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enasidenib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enasidenib Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enasidenib Epistaxis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Enasidenib Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enasidenib Febrile neutropenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Enasidenib Leukocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enasidenib Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enasidenib Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enasidenib Pancytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enasidenib Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enasidenib Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Enasidenib Pyrexia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Enasidenib Renal failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enasidenib Sepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Enasidenib Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Enasidenib Tumour lysis syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin Abdominal pain 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin Anaemia 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Enoxaparin Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin Blood creatinine increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Enoxaparin Cardiac failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Enoxaparin Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin Cerebral haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Enoxaparin Cerebrovascular accident 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin Contusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enoxaparin Deep vein thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin Dyspnoea 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Enoxaparin Epistaxis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin Gastric haemorrhage 0.0 0.0 1.0 0.0 0.0 1.0 0.0 Enoxaparin Gastric ulcer 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Enoxaparin Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 1.0 0.0 Enoxaparin Haematemesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin Haematochezia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin Haematocrit decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin Haematoma 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Enoxaparin Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin Haemoglobin decreased 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Enoxaparin Haemoptysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin Haemorrhage 0.0 0.0 1.0 0.0 0.0 1.0 0.0 Enoxaparin Haemorrhage intracranial 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enoxaparin Hypoaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin Hypotension 1.0 1.0 0.0 0.0 0.0 1.0 0.0 Enoxaparin Melaena 0.0 0.0 1.0 0.0 0.0 1.0 0.0 Enoxaparin Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enoxaparin Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin Premature baby 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enoxaparin Pulmonary embolism 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin Renal failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Enoxaparin Respiratory failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin Shock haemorrhagic 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enoxaparin Subarachnoid haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Enoxaparin Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Enoxaparin Unresponsive to stimuli 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Enoxaparin Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin sodium Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin sodium Atrial fibrillation 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Enoxaparin sodium Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Enoxaparin sodium Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin sodium Dyspnoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin sodium Ecchymosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin sodium Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Enoxaparin sodium Haematoma 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin sodium Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin sodium Haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Enoxaparin sodium Hyperkalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Enoxaparin sodium Inflammation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Enoxaparin sodium Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin sodium Nervous system disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin sodium Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin sodium Oedema peripheral 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin sodium Pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Enoxaparin sodium Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enoxaparin sodium Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin sodium Pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enoxaparin sodium Purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin sodium Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin sodium Skin necrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enoxaparin sodium Thrombocytopenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Enoxaparin sodium Urticaria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Entacapone Acute respiratory failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Entacapone Blood creatine phosphokinase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Entacapone Cardiac failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Entacapone Chromaturia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Entacapone Cognitive disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Entacapone Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Entacapone Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Entacapone Decubitus ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Entacapone Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Entacapone Delusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Entacapone Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Entacapone Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Entacapone Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Entacapone Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Entacapone Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Entacapone Feeling abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Entacapone Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Entacapone Haematemesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Entacapone Hallucination 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Entacapone Hallucination, visual 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Entacapone Hyperkinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Entacapone Hypokinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Entacapone Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Entacapone Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Entacapone Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Entacapone Neuroleptic malignant syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Entacapone Nocturia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Entacapone Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Entacapone Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Entacapone Pneumonia aspiration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Entacapone Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Entacapone Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Entacapone Sleep disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Entacapone Somnolence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Entacapone White blood cell count increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Entecavir Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Entecavir Acute hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Entecavir Alanine aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Entecavir Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Entecavir Anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Entecavir Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Entecavir Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Entecavir Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Entecavir Drug resistance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Entecavir Dysphagia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Entecavir Dyspnoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Entecavir Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Entecavir Hepatic cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Entecavir Hepatic cirrhosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Entecavir Hepatic encephalopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Entecavir Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Entecavir Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Entecavir Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Entecavir Interstitial lung disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Entecavir Jaundice 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Entecavir Liver disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Entecavir Lung neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Entecavir Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Entecavir Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Entecavir Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Entecavir Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Entecavir Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Entecavir Premature baby 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Entecavir Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Entecavir Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Entecavir Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Entecavir Rhabdomyolysis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Entecavir Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Entecavir Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Abasia 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Enzalutamide Abdominal discomfort 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Abdominal distension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Abdominal pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Abdominal pain lower 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Abnormal dreams 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Acute coronary syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Acute kidney injury 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Acute myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Acute respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Aggression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Agitation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Alanine aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Amnesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Anaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Anger 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Angina pectoris 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Angioedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Aphasia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Arthralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Arthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Aspartate aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Asthenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Back pain 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Balance disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Basal cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Blindness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Blood bilirubin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Blood glucose decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Blood glucose increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Blood pressure decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Blood pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Blood triglycerides increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Blood urine present 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Bone marrow failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Bone pain 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Bradyphrenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide C-reactive protein increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Cachexia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Cardiac disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Cardiac failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Cardiac failure acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Cardiac failure congestive 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Cardiovascular disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Cerebral infarction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Choking 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Chronic kidney disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Chronic obstructive pulmonary disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Circulatory collapse 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Clostridium difficile infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Coma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Confusional state 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Constipation 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Contusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Coronary artery disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Cough 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Cystitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Decubitus ulcer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Dehydration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Dementia 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Depressed level of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Diarrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Diplopia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Disorientation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Disseminated intravascular coagulation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Dizziness 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Drug intolerance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Drug resistance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Dry eye 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Dry skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Dysgeusia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Dysphagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Dysphonia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Dyspnoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Eating disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Emotional disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Encephalopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Epilepsy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Epistaxis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Eye haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Eye irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Eye pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Failure to thrive 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Fatigue 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Febrile neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Feeding disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Feeling abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Feeling jittery 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Femur fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Flank pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Flatulence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Fluid overload 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Full blood count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Gallbladder disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Gastritis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Gastrointestinal disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Generalised oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Gynaecomastia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Haematocrit decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Haemoglobin decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Haemorrhagic stroke 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Hallucination 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Hepatic cirrhosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Hepatic encephalopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Hepatic function abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Hip fracture 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Hot flush 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Hydronephrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Hypercalcaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Hyperhidrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Hypersomnia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Hypoacusis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Hypoaesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Hypoglycaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Hypokalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Hypophagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Hypotension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Hypothyroidism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Ileus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Ill-defined disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Inappropriate antidiuretic hormone secretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Incontinence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Interstitial lung disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Intestinal obstruction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Irritability 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Ischaemic stroke 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Enzalutamide Joint swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Lacrimation increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Lethargy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Libido decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Localised infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Loss of consciousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Lung infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Lymphadenopathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Lymphoedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Malaise 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Malnutrition 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Memory impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Metastases to central nervous system 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Metastases to liver 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Metastatic neoplasm 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Middle insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Mitral valve incompetence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Mobility decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Mood swings 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Movement disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Muscle spasms 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Muscular weakness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Musculoskeletal chest pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Musculoskeletal stiffness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Nasopharyngitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Nausea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Neoplasm 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Neuralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Night sweats 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Ocular hyperaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Oedema peripheral 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Osteoarthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Osteonecrosis of jaw 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Pain in extremity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Pancytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Paraesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Parkinsonism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Peripheral swelling 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Platelet count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Pleural effusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Pollakiuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Posterior reversible encephalopathy syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Prostate cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Psychotic disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Pulmonary embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Pulmonary fibrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Pyrexia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Rash generalised 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Renal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Respiratory disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Restless legs syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Enzalutamide Restlessness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Rhinorrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Salivary hypersecretion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Sepsis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Sleep disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Small intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Sneezing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Somnolence 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Speech disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Staphylococcal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Stevens-Johnson syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Subarachnoid haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Subdural haematoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Swelling 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Tinnitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Toothache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Transient ischaemic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Unevaluable event 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Unresponsive to stimuli 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Urinary retention 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Urinary tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Urosepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Enzalutamide Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Visual acuity reduced 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Vomiting 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Enzalutamide Weight decreased 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Enzalutamide White blood cell count increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epinephrine Acute kidney injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Acute myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Acute pulmonary oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Agitation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Anaphylactic reaction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Anaphylactic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Arrhythmia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Asthma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Blood pressure decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Blood pressure increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Cardiogenic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Cardiomyopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Chest discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Circulatory collapse 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Cyanosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Death 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Drug hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Ejection fraction decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Electrocardiogram abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epinephrine Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Feeling abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Haemodynamic instability 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Headache 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Heart rate decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Epinephrine Heart rate increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Hyperhidrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Epinephrine Hypersensitivity 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Hypertensive crisis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Hypoaesthesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Hypoxia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Intraocular pressure increased 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Epinephrine Left ventricular dysfunction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Malaise 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Epinephrine Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Muscle spasms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Myocardial ischaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Oxygen saturation decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Pain in extremity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Pallor 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Epinephrine Pruritus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Pulmonary oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Renal failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epinephrine Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Respiratory distress 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Seizure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Septic shock 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Epinephrine Sinus tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Skin discolouration 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Epinephrine Stress cardiomyopathy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Epinephrine Suicide attempt 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epinephrine Swelling 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Epinephrine Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Tachypnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Throat tightness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Treatment failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Tremor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Troponin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epinephrine Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Ventricular extrasystoles 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Ventricular fibrillation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epinephrine Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epinephrine Visual acuity reduced 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Epinephrine Vomiting 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Epinephrine Wheezing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epirubicin Abdominal pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epirubicin Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epirubicin Acute kidney injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Epirubicin Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epirubicin Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epirubicin Bone marrow failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epirubicin Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Epirubicin Cardiac failure 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Epirubicin Cardiomyopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epirubicin Chills 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epirubicin Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epirubicin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Epirubicin Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epirubicin Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epirubicin Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Epirubicin Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Epirubicin Dyspepsia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epirubicin Dyspnoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Epirubicin Ejection fraction decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Epirubicin Extravasation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epirubicin Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Epirubicin Febrile neutropenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Epirubicin Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Epirubicin Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epirubicin Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Epirubicin Leukopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Epirubicin Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epirubicin Malaise 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Epirubicin Mucosal inflammation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Epirubicin Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Epirubicin Neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Epirubicin Pancytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epirubicin Platelet count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Epirubicin Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Epirubicin Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epirubicin Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Epirubicin Respiratory distress 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epirubicin Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Epirubicin Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Epirubicin Thrombocytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Epirubicin White blood cell count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Epirubicin hydrochloride Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epirubicin hydrochloride Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epirubicin hydrochloride Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Epirubicin hydrochloride Aspartate aminotransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Epirubicin hydrochloride Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Epirubicin hydrochloride Bone marrow failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Epirubicin hydrochloride Cardiomyopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epirubicin hydrochloride Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epirubicin hydrochloride Chills 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epirubicin hydrochloride Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epirubicin hydrochloride Diarrhoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epirubicin hydrochloride Dysgeusia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Epirubicin hydrochloride Dyspepsia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epirubicin hydrochloride Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epirubicin hydrochloride Dyspnoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Epirubicin hydrochloride Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Epirubicin hydrochloride Febrile neutropenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epirubicin hydrochloride Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epirubicin hydrochloride Hot flush 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Epirubicin hydrochloride Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epirubicin hydrochloride Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epirubicin hydrochloride Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Epirubicin hydrochloride Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epirubicin hydrochloride Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epirubicin hydrochloride Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Epirubicin hydrochloride Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epirubicin hydrochloride Neuropathy peripheral 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Epirubicin hydrochloride Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Epirubicin hydrochloride Pain in extremity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Epirubicin hydrochloride Pancytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epirubicin hydrochloride Paraesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Epirubicin hydrochloride Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Epirubicin hydrochloride Polyneuropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Epirubicin hydrochloride Pulmonary embolism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epirubicin hydrochloride Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Epirubicin hydrochloride Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Epirubicin hydrochloride Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epirubicin hydrochloride Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eplerenone Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eplerenone Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eplerenone Alanine aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eplerenone Aspartate aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eplerenone Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eplerenone Atrial fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eplerenone Cardiac failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eplerenone Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eplerenone Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eplerenone Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Eplerenone Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eplerenone Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Eplerenone Dyspnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eplerenone Gamma-glutamyltransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eplerenone Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eplerenone Hyperkalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eplerenone Hypokalaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Eplerenone Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eplerenone Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eplerenone Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Eplerenone Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eplerenone Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eplerenone Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eplerenone Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eplerenone Pneumonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eplerenone Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eplerenone Pulmonary oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eplerenone Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Abdominal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Abdominal distension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Abdominal pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Abdominal pain lower 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Acute respiratory failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Agitation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Alopecia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Anaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Anal incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Angina pectoris 0.0 0.0 1.0 0.0 1.0 0.0 0.0 Epoprostenol Anuria 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Epoprostenol Anxiety 0.0 0.0 1.0 0.0 1.0 0.0 0.0 Epoprostenol Appetite disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Arrhythmia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Arthritis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Ascites 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Asthenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Asthma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Atrial fibrillation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Bacteraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Bacterial infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Blister 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Blood count abnormal 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Blood creatinine increased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Blood disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Blood glucose decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Blood pressure abnormal 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Blood pressure decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Blood sodium decreased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Blood urine present 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Bone pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Bradycardia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Burning sensation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol C-reactive protein increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Cardiac arrest 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Cardiac disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Cardiac failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Cardiac failure acute 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Cardiac failure congestive 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Cardio-respiratory arrest 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Cardiogenic shock 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Cardiomegaly 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Cardiopulmonary failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Epoprostenol Cataract 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Cerebrovascular accident 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Chills 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Cholecystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Chronic obstructive pulmonary disease 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Circulatory collapse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Epoprostenol Clostridium difficile infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Colon cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Epoprostenol Confusional state 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Connective tissue disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epoprostenol Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Contusion 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Crying 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Cyanosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Cystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Death 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Decreased appetite 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Deep vein thrombosis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Dehydration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Delirium 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Depressed level of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Depressed mood 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Depression 0.0 0.0 1.0 0.0 1.0 0.0 0.0 Epoprostenol Dermatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Dermatitis contact 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Diabetes mellitus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Diarrhoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Disease progression 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Disorientation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Diverticulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Dizziness postural 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Drug hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Drug intolerance 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Dry mouth 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Dry skin 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Dysgeusia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Dyspepsia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Dysphagia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Dyspnoea exertional 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Ear infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Ear pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Embolism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epoprostenol Encephalopathy 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Eosinophilia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Epoprostenol Epistaxis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Erythema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Faeces discoloured 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Fatigue 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Feeling abnormal 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Feeling cold 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Feeling hot 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Flatulence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Fluid overload 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Fluid retention 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Flushing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Fungal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Gastric disorder 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Epoprostenol Gastric haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Gastroenteritis viral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Gastrointestinal haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Generalised oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Gout 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Haematemesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Haematochezia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Haematoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Epoprostenol Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Haemodynamic instability 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Haemoglobin decreased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Haemoptysis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Heart rate irregular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Hepatic cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Epoprostenol Hepatic cirrhosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Epoprostenol Herpes zoster 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Hip fracture 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Hot flush 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Hypercalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Hyperkalaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Hypertension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Hyperthyroidism 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Hypoaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Hyponatraemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Hypotension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Hypoxia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Ill-defined disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Influenza like illness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Injection site pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Interstitial lung disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Joint swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Laceration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Lacrimation increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Lethargy 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Limb discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Liver disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Liver function test abnormal 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Epoprostenol Local swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Localised infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Loss of consciousness 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Lower respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Lung disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Lung infiltration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Epoprostenol Lymphadenopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Malaise 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Malnutrition 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Epoprostenol Mass 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Melaena 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Memory impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Mental disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Mental status changes 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Migraine 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Epoprostenol Muscle spasms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Muscular weakness 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Musculoskeletal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Musculoskeletal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Myalgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Myocardial infarction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Nasal congestion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Nausea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Neck pain 0.0 0.0 1.0 0.0 1.0 0.0 0.0 Epoprostenol Neoplasm malignant 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Nervousness 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Neuralgia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Neuropathy peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Night sweats 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Oedema peripheral 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Oropharyngeal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Oxygen saturation decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Pain in jaw 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Pain of skin 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Pallor 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Pancytopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Panic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Paraesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Pericardial effusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Peripheral swelling 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Pharyngeal oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Pharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Photophobia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Platelet count decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Pleural effusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Pneumothorax 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Polyuria 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Premature delivery 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Productive cough 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Pulmonary embolism 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Pulmonary haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Pulmonary hypertension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Pulmonary oedema 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Rash erythematous 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Rash generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Rash macular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Rash papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Rash pruritic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Red blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Renal disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Renal failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Renal impairment 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Epoprostenol Respiratory disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Respiratory distress 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Respiratory failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Retching 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Rhinorrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Seizure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Sepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Septic shock 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Epoprostenol Shock haemorrhagic 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Epoprostenol Sinus disorder 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Sinusitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Skin discolouration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Skin disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Skin exfoliation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Skin infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Skin irritation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Skin reaction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Skin ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Splenomegaly 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Staphylococcal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Epoprostenol Suicidal ideation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Supraventricular tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Swelling face 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Syncope 1.0 0.0 1.0 0.0 1.0 0.0 0.0 Epoprostenol Systemic lupus erythematosus 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Throat irritation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Thrombocytopenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Transient ischaemic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Troponin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Unevaluable event 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Unresponsive to stimuli 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Upper respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Urinary incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Urinary tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Urine output decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Urticaria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Vaginal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Vision blurred 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Vomiting 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Weight decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Weight increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol Wheezing 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol White blood cell count decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol White blood cell count increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol sodium Abdominal pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol sodium Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol sodium Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol sodium Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol sodium Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol sodium Bradycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Epoprostenol sodium Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol sodium Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol sodium Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol sodium Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol sodium Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol sodium Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol sodium Flushing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol sodium Haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol sodium Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol sodium Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol sodium Hypotension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol sodium Hypoxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Epoprostenol sodium Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol sodium Musculoskeletal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol sodium Myalgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol sodium Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol sodium Oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol sodium Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol sodium Pain in jaw 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol sodium Pallor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol sodium Pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Epoprostenol sodium Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol sodium Sepsis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol sodium Tachycardia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol sodium Urticaria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Epoprostenol sodium Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eptifibatide Myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eptifibatide Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Erdafitinib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erdafitinib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erdafitinib Mucosal inflammation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erdafitinib Stomatitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ergocalciferol Abdominal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ergocalciferol Asthenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ergocalciferol Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ergocalciferol Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ergocalciferol Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ergocalciferol Hypercalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ergocalciferol Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ergocalciferol Influenza 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ergocalciferol Malnutrition 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ergocalciferol Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ergocalciferol Pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ergocalciferol Pain in extremity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ergocalciferol Polyuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ergocalciferol Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ergocalciferol Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Alanine aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Aspartate aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eribulin Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Bone pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Cardiac failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Febrile neutropenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eribulin Hepatic failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eribulin Hyperglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Hypotension 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Eribulin Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Influenza like illness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Interstitial lung disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Leukopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Lung infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Lymphopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Eribulin Mucosal inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Multiple organ dysfunction syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eribulin Nausea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eribulin Neuropathy peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eribulin Neutrophil count decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Pericardial effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Pleural effusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Pneumonitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Pneumothorax 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Pulmonary embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eribulin Renal failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Respiratory failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Eribulin Sepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Eribulin Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Eribulin Stomatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Thrombocytopenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin White blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin mesylate Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin mesylate Alopecia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin mesylate Anaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Eribulin mesylate Asthenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eribulin mesylate Bone pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin mesylate Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin mesylate Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin mesylate Decreased appetite 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Eribulin mesylate Diarrhoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eribulin mesylate Dizziness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eribulin mesylate Dysgeusia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin mesylate Dyspnoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Eribulin mesylate Fatigue 1.0 1.0 1.0 1.0 0.0 0.0 0.0 Eribulin mesylate Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin mesylate Mucosal inflammation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin mesylate Muscular weakness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Eribulin mesylate Myalgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin mesylate Nausea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Eribulin mesylate Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Eribulin mesylate Neutropenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin mesylate Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin mesylate Pyrexia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin mesylate Stomatitis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Eribulin mesylate Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eribulin mesylate Vomiting 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Erlotinib Abasia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Abdominal discomfort 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Abdominal distension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Abdominal pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Abdominal pain upper 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Acne 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Acute kidney injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Acute myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Acute respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Alanine aminotransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Erlotinib Alopecia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Amnesia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Amylase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Erlotinib Anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Anxiety 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Aphasia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Arrhythmia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Erlotinib Arthralgia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Arthritis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Aspartate aminotransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Erlotinib Asthenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Back pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Blood glucose decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Erlotinib Blood urine present 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Erlotinib Bone marrow failure 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Erlotinib Bone pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Bronchitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Cachexia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Cardiac disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Cardiac failure congestive 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Cardiomyopathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Erlotinib Cellulitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Chest discomfort 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Chest pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Chills 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Cholelithiasis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Chronic obstructive pulmonary disease 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Clostridium difficile infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Cognitive disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Colitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Colitis ischaemic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Erlotinib Coma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Confusional state 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Conjunctivitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Constipation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Cough 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Deafness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Deep vein thrombosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Dehydration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Erlotinib Dementia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Depression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Dermatitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Diarrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Discomfort 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Dizziness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Drug eruption 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Drug intolerance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Drug resistance 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Erlotinib Dry eye 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Erlotinib Dry mouth 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Dry skin 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Erlotinib Dysgeusia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Dyspepsia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Dysphagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Dysphonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Dyspnoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Dyspnoea exertional 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Dysuria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Eating disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Epistaxis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Erythema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Eye disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Erlotinib Eye irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Erlotinib Eye pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Erlotinib Fatigue 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Feeding disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Feeling abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Flatulence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Gait disturbance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Gastric disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Gastrointestinal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Erlotinib Gastrooesophageal reflux disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Haematemesis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Haemoglobin decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Haemoptysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Headache 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Hepatic enzyme increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Hepatic function abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Hepatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Erlotinib Hepatotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Erlotinib Herpes zoster 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Hip fracture 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Hyperhidrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Hypersensitivity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Erlotinib Hypoacusis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Hypoaesthesia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Hypokalaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Hypophagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Hypoxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Ileus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Erlotinib Ill-defined disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Insomnia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Interstitial lung disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Intestinal obstruction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Jaundice 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Lethargy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Liver disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Liver function test abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Loss of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Lung disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Lung infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Malaise 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Mass 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Mental status changes 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Metastases to central nervous system 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Metastases to liver 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Metastases to lung 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Metastatic neoplasm 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Mouth ulceration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Mucosal inflammation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Muscle spasms 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Muscular weakness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Musculoskeletal chest pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Musculoskeletal discomfort 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Musculoskeletal pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Myalgia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Nausea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Neck pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Neoplasm 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Erlotinib Nervous system disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Erlotinib Neuropathy peripheral 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Neutropenia 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Erlotinib Ocular hyperaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Erlotinib Oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Oedema peripheral 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Oesophagitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Oropharyngeal pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Orthostatic hypotension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Pain in extremity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Pain of skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Erlotinib Pancreatic carcinoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Erlotinib Pancreatitis acute 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Paraesthesia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Pericardial effusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Peripheral swelling 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Platelet count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Pleural effusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Pneumonitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Pneumothorax 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Productive cough 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Protein urine present 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Proteinuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Erlotinib Pruritus 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Erlotinib Pulmonary embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Pulmonary haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Pulmonary mass 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Pyrexia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Rash 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Rash erythematous 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Respiratory disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Seizure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Skin disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Skin exfoliation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Skin reaction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Small intestinal obstruction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Somnolence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Stomatitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Swelling 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Syncope 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Tachycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Tenderness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Thrombocytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Thrombosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Treatment failure 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Erlotinib Tremor 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Ulcer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Urinary tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Vomiting 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib Weight decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib hydrochloride Abdominal pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib hydrochloride Alopecia 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Erlotinib hydrochloride Anxiety 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib hydrochloride Bone pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Erlotinib hydrochloride Constipation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib hydrochloride Cough 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Erlotinib hydrochloride Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib hydrochloride Depression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib hydrochloride Diarrhoea 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Erlotinib hydrochloride Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Erlotinib hydrochloride Dry skin 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Erlotinib hydrochloride Dyspepsia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib hydrochloride Dyspnoea 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Erlotinib hydrochloride Fatigue 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib hydrochloride Flatulence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Erlotinib hydrochloride Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Erlotinib hydrochloride Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Erlotinib hydrochloride Insomnia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib hydrochloride Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Erlotinib hydrochloride Nausea 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Erlotinib hydrochloride Neuropathy peripheral 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Erlotinib hydrochloride Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Erlotinib hydrochloride Pyrexia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Erlotinib hydrochloride Rash 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Erlotinib hydrochloride Vomiting 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Erlotinib hydrochloride Weight decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ertapenem Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ertapenem Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ertapenem Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ertapenem Hallucination, visual 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ertapenem Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ertapenem Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ertapenem Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ertapenem sodium Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ertapenem sodium Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ertapenem sodium Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ertapenem sodium Clostridium difficile colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ertapenem sodium Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ertapenem sodium Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ertapenem sodium Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ertapenem sodium Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ertapenem sodium Dyskinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ertapenem sodium Dyspnoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ertapenem sodium Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ertapenem sodium Hallucination 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Ertapenem sodium Insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ertapenem sodium Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ertapenem sodium Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ertapenem sodium Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ertapenem sodium Myoclonus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ertapenem sodium Pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ertapenem sodium Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ertapenem sodium Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ertapenem sodium Skin lesion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ertapenem sodium Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Erythromycin Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Erythromycin Drug hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Erythromycin Malaise 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Erythromycin Premature baby 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Erythromycin Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Erythromycin Stevens-Johnson syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Erythromycin Torsade de pointes 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Erythromycin Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Escitalopram oxalate Abdominal pain 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Abnormal dreams 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Escitalopram oxalate Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Aggression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Agitation 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Agranulocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Akathisia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Amnesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Anger 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Apathy 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Escitalopram oxalate Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Atrial fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Bradycardia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Cerebrovascular accident 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Chest pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Confusional state 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Decreased appetite 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Deep vein thrombosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Escitalopram oxalate Delusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Depersonalisation/derealisation disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Depression 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Escitalopram oxalate Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Escitalopram oxalate Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Diplopia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Escitalopram oxalate Disorientation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Dysarthria 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Dyskinesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Dyspnoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Dystonia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Dysuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Escitalopram oxalate Electrocardiogram QT prolonged 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Erectile dysfunction 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Flatulence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Gait disturbance 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Gastrointestinal haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Generalised tonic-clonic seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Escitalopram oxalate Hallucination, auditory 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Hallucination, visual 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Heart rate decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Hepatic enzyme increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Escitalopram oxalate Hepatic failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Hepatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Hypertension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Inappropriate antidiuretic hormone secretion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Influenza like illness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Insomnia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Intentional self-injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Irritability 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Leukopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Libido decreased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Malaise 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Mood swings 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Muscle spasms 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Muscular weakness 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Musculoskeletal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Escitalopram oxalate Musculoskeletal stiffness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Mydriasis 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Myoclonus 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Nasal congestion 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Nausea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Neck pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Escitalopram oxalate Nervousness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Nightmare 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Nystagmus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Oedema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Pain in extremity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Palpitations 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Paranoia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Photosensitivity reaction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Pollakiuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Priapism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Pulmonary embolism 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Pyrexia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Rash 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Restless legs syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Restlessness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Seizure 0.0 1.0 1.0 0.0 1.0 0.0 0.0 Escitalopram oxalate Somnolence 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Suicidal ideation 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Escitalopram oxalate Suicide attempt 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Syncope 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Tinnitus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Torsade de pointes 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Toxic epidermal necrolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Tremor 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Escitalopram oxalate Urinary retention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Urinary tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Escitalopram oxalate Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Vertigo 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Visual impairment 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Escitalopram oxalate Weight decreased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Escitalopram oxalate Weight increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Esketamine Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esketamine Blood pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esketamine Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Esketamine Crying 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esketamine Depression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esketamine Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esketamine Dysgeusia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esketamine Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esketamine Feeling abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esketamine Hallucination 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esketamine Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esketamine Hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esketamine Hypoaesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esketamine Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esketamine Malaise 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esketamine Mental disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esketamine Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esketamine Panic attack 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esketamine Sedation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esketamine Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Esketamine Throat irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esketamine Tremor 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esketamine Vomiting 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Eslicarbazepine acetate Amnesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Eslicarbazepine acetate Balance disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Eslicarbazepine acetate Chills 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eslicarbazepine acetate Confusional state 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eslicarbazepine acetate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Eslicarbazepine acetate Decreased appetite 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Eslicarbazepine acetate Disorientation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Eslicarbazepine acetate Disturbance in attention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Eslicarbazepine acetate Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Eslicarbazepine acetate Dysarthria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eslicarbazepine acetate Feeling abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Eslicarbazepine acetate Generalised tonic-clonic seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eslicarbazepine acetate Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Eslicarbazepine acetate Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eslicarbazepine acetate Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Eslicarbazepine acetate Memory impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Eslicarbazepine acetate Seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Eslicarbazepine acetate Somnolence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Eslicarbazepine acetate Suicidal ideation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Eslicarbazepine acetate Vertigo 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Eslicarbazepine acetate Weight decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esomeprazole Abdominal distension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Esomeprazole Abdominal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Esomeprazole Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Agranulocytosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Alanine aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Esomeprazole Aspartate aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Back pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esomeprazole Blood alkaline phosphatase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Burning sensation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Chills 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esomeprazole Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Deep vein thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Diarrhoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esomeprazole Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Epistaxis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Face oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Esomeprazole Feeling abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Esomeprazole Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Haematuria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Esomeprazole Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Esomeprazole Hepatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Hypocalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Hypoglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Hypomagnesaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esomeprazole Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Leukopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Esomeprazole Lymphadenopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esomeprazole Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Pancytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Paraesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Esomeprazole Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Renal failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Restlessness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esomeprazole Rhabdomyolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Esomeprazole Shock 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Somnolence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Esomeprazole Stevens-Johnson syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Esomeprazole Syncope 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Esomeprazole Tachycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Esomeprazole Thrombocytopenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Toxic epidermal necrolysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Esomeprazole Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Esomeprazole Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Abdominal pain upper 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Esomeprazole magnesium Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Agranulocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Alanine aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Esomeprazole magnesium Arthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Esomeprazole magnesium Arthropathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Esomeprazole magnesium Aspartate aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Esomeprazole magnesium Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Esomeprazole magnesium Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Candida infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esomeprazole magnesium Chest pain 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Esomeprazole magnesium Chills 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Esomeprazole magnesium Confusional state 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Esomeprazole magnesium Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Esomeprazole magnesium Diarrhoea 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Esomeprazole magnesium Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esomeprazole magnesium Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esomeprazole magnesium Dysphagia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Dysuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esomeprazole magnesium Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esomeprazole magnesium Face oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Esomeprazole magnesium Fluid retention 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Flushing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esomeprazole magnesium Gastritis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Gastrointestinal disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esomeprazole magnesium Gastrointestinal haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Generalised oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Haematuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esomeprazole magnesium Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Esomeprazole magnesium Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Hepatic function abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Hyperbilirubinaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Hypertension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Esomeprazole magnesium Hypocalcaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Hypomagnesaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Esomeprazole magnesium Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Esomeprazole magnesium Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Esomeprazole magnesium Muscular weakness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Esomeprazole magnesium Musculoskeletal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Esomeprazole magnesium Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Esomeprazole magnesium Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Esomeprazole magnesium Osteoarthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Esomeprazole magnesium Pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esomeprazole magnesium Pancreatitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Esomeprazole magnesium Pancytopenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Esomeprazole magnesium Photosensitivity reaction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Platelet count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Pollakiuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esomeprazole magnesium Polyp 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Esomeprazole magnesium Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Rhinitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esomeprazole magnesium Shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Sinusitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Esomeprazole magnesium Sleep disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Esomeprazole magnesium Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Toxic epidermal necrolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Tremor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Tubulointerstitial nephritis 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Esomeprazole magnesium Urine abnormality 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esomeprazole magnesium Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Esomeprazole magnesium Visual field defect 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole magnesium Weight decreased 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Esomeprazole magnesium Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Esomeprazole magnesium White blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole sodium Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole sodium Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Esomeprazole sodium Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Esomeprazole sodium Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Esomeprazole sodium Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Estradiol Abdominal distension 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Estradiol Abdominal pain upper 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Aggression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Estradiol Agitation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Alopecia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Estradiol Amnesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Estradiol Angioedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Estradiol Aphasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Estradiol Arthralgia 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Estradiol Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Estradiol Asthma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Back pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Estradiol Balance disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Estradiol Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Estradiol Blister 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Blood pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Breast cancer 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Estradiol Breast enlargement 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Estradiol Breast pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Estradiol Burning sensation 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Estradiol Candida infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Cardiac disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Estradiol Cerebrovascular accident 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Estradiol Chest pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Estradiol Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Cystitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Estradiol Deep vein thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Estradiol Dementia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Depressed mood 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Estradiol Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Estradiol Discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Estradiol Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Estradiol Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Estradiol Drug interaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Estradiol Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Dry eye 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Dry skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Dysarthria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Estradiol Dyskinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Estradiol Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Estradiol Eczema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Embolism venous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Epilepsy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Estradiol Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Estradiol Feeling abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Estradiol Fluid retention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Flushing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Fungal infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Estradiol Gastrointestinal disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Gastrooesophageal reflux disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Hallucination, visual 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Estradiol Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Estradiol Hemiparesis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Estradiol Hot flush 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Estradiol Hyperhidrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Estradiol Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Estradiol Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Estradiol Ill-defined disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Estradiol Irritability 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Joint swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Limb discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Liver function test increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Lymphadenopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Estradiol Malaise 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Estradiol Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Estradiol Menopausal symptoms 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Estradiol Mental impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Migraine 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Estradiol Mood altered 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Estradiol Movement disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Estradiol Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Estradiol Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Estradiol Myalgia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Estradiol Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Estradiol Neck pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Estradiol Neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Nervous system disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Estradiol Nervousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Night sweats 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Oedema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Estradiol Osteoarthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Estradiol Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Estradiol Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Pancreatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Estradiol Panic attack 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Estradiol Peripheral swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Phlebitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Estradiol Photosensitivity reaction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Estradiol Pollakiuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Estradiol Poor quality sleep 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Estradiol Pulmonary embolism 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Estradiol Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Rash erythematous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Rash pruritic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Seizure 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Estradiol Skin burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Skin discolouration 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Skin disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Skin reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Sleep disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Estradiol Somnolence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Speech disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Estradiol Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Estradiol Swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Thrombocytopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Estradiol Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Estradiol Urinary incontinence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Urinary tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Vaginal haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Vaginal infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Estradiol Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Estradiol Vulvovaginal mycotic infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Estradiol Weight decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Estradiol Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Eszopiclone Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Eszopiclone Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Eszopiclone Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eszopiclone Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Eszopiclone Delirium 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Eszopiclone Feeling abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eszopiclone Paranoia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Eszopiclone Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etelcalcetide Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Etelcalcetide Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Etelcalcetide Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Etelcalcetide Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ethambutol hydrochloride Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ethosuximide Systemic lupus erythematosus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Etodolac Gastric haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Etonogestrel Abdominal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etonogestrel Abdominal distension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Abdominal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Abdominal pain lower 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Abdominal pain upper 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Abortion spontaneous 0.0 0.0 0.0 0.0 1.0 0.0 1.0 Etonogestrel Acne 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Affect lability 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etonogestrel Aggression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etonogestrel Agitation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Alopecia 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Amenorrhoea 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Etonogestrel Amnesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Anaemia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Anger 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Anxiety 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Arthralgia 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Asthenia 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Back pain 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Balance disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etonogestrel Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Blood pressure increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Breast cancer 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Etonogestrel Breast pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etonogestrel Cardiac disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Cellulitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etonogestrel Cerebrovascular accident 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Chest discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Chest pain 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Chills 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Contusion 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Crying 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Cyst 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Etonogestrel Decreased appetite 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Deep vein thrombosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Depressed mood 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Depression 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etonogestrel Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Dizziness 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Dysmenorrhoea 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Etonogestrel Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Dyspnoea 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Eating disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etonogestrel Emotional disorder 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Emotional distress 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Epilepsy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etonogestrel Erythema 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Fatigue 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Fear 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Feeling abnormal 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Feeling hot 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etonogestrel Foetal death 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etonogestrel Fungal infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Gallbladder disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Gastrointestinal disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etonogestrel Gastrooesophageal reflux disease 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Haemorrhage 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Headache 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Heart rate increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Hot flush 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Hyperhidrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Hypertension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Etonogestrel Hypokinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Increased appetite 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etonogestrel Infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etonogestrel Influenza like illness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Insomnia 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Irritability 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Lethargy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etonogestrel Libido decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Limb discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etonogestrel Loss of consciousness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Loss of libido 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Malaise 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Menorrhagia 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Menstrual disorder 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Etonogestrel Menstruation irregular 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Etonogestrel Mental disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Metrorrhagia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Etonogestrel Migraine 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Mood altered 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Mood swings 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Motor dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Movement disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Muscle spasms 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Etonogestrel Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Musculoskeletal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Nausea 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Neck pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Nephrolithiasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etonogestrel Nervous system disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Nervousness 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Neuralgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etonogestrel Night sweats 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etonogestrel Nightmare 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Obesity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Oropharyngeal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etonogestrel Pain 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Pain in extremity 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Etonogestrel Pallor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Palpitations 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Panic attack 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Paraesthesia 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Etonogestrel Paranoia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Pelvic pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Peripheral swelling 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Pneumothorax 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Pollakiuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etonogestrel Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etonogestrel Pulmonary embolism 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Pyrexia 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Rash 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Etonogestrel Seizure 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Etonogestrel Skin disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etonogestrel Sleep disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Somnolence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Speech disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Staphylococcal infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etonogestrel Stress 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Suicidal ideation 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Suicide attempt 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Syncope 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Systemic lupus erythematosus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etonogestrel Tachycardia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Thrombosis 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Tremor 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Urinary tract infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Urticaria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Vaginal discharge 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Etonogestrel Vaginal haemorrhage 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Etonogestrel Vaginal infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Vertigo 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Vision blurred 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Etonogestrel Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Vomiting 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Weight decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Etonogestrel Weight increased 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Etoposide Abdominal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Etoposide Acute coronary syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Etoposide Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Etoposide Acute myeloid leukaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Agranulocytosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Etoposide Alanine aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etoposide Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Angioedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Etoposide Ascites 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Aspartate aminotransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etoposide Asthenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Atrial fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Back pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Blood albumin decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Blood creatinine increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Blood pressure decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Body temperature increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Etoposide Bone marrow failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Brain oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Etoposide Candida infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Etoposide Cardiotoxicity 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Etoposide Cellulitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Etoposide Chest discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Chills 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Cholestasis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Circulatory collapse 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Clostridium difficile colitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Colitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Confusional state 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Etoposide Congestive cardiomyopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Etoposide Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Cyanosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Etoposide Decreased appetite 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Etoposide Diarrhoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Disease progression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Disseminated intravascular coagulation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Drug resistance 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Etoposide Dyspnoea 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Etoposide Encephalitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etoposide Encephalopathy 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Etoposide Epistaxis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Etoposide Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Face oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Febrile neutropenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Etoposide Flushing 0.0 1.0 0.0 0.0 0.0 1.0 1.0 Etoposide Gastrointestinal disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etoposide Gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Haemodynamic instability 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Haemoglobin decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Etoposide Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Etoposide Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Hepatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etoposide Hepatotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etoposide Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Hypocalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Etoposide Hypokalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Hyponatraemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Etoposide Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Inappropriate antidiuretic hormone secretion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etoposide Infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Etoposide Interstitial lung disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Etoposide Intestinal perforation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Etoposide Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Etoposide Leukopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Lip swelling 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Liver disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etoposide Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Lymphopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Malignant neoplasm progression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Metabolic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Metastases to lung 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etoposide Mouth ulceration 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Mucosal inflammation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Myelodysplastic syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Etoposide Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Etoposide Nephropathy toxic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etoposide Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etoposide Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Etoposide Oesophagitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Etoposide Oxygen saturation decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Etoposide Pancreatitis acute 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Etoposide Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Pericarditis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Etoposide Platelet count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Pleural effusion 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Pneumonitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Etoposide Pulmonary embolism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Pulmonary fibrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Etoposide Pulmonary haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Etoposide Pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Etoposide Pyrexia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Etoposide Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Red blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Etoposide Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Renal impairment 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Etoposide Respiratory distress 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Etoposide Somnolence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Etoposide Stomatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Swelling 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Etoposide Swelling face 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Syncope 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etoposide Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Treatment failure 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Etoposide Tumour lysis syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Urinary tract infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Urine output decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Etoposide Urosepsis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Etoposide Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide phosphate Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide phosphate Bone marrow failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoposide phosphate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Etoposide phosphate Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etoricoxib Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Etoricoxib Atrial fibrillation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etoricoxib Gamma-glutamyltransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Etoricoxib Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Etoricoxib Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Etoricoxib Renal failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Etoricoxib Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Etravirine Acute kidney injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Etravirine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Etravirine Drug resistance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Etravirine Myocardial infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Etravirine Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Etravirine Premature baby 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Etravirine Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Etravirine Treatment failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Abasia 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Everolimus Abdominal discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Abdominal distension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Abdominal pain 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Abdominal pain lower 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Abdominal pain upper 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Abnormal faeces 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Abscess 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Acne 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Everolimus Acute coronary syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Acute hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Acute myocardial infarction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Acute pulmonary oedema 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Acute respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Ageusia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Everolimus Agitation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Alanine aminotransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Everolimus Altered state of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Amenorrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Everolimus Amnesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Anaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Anal incontinence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Anger 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Everolimus Angina pectoris 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Anuria 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Anxiety 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Aphasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Everolimus Aplastic anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Appendicitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Arrhythmia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Ascites 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Aspartate aminotransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Asthenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Atelectasis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Atrial fibrillation 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Back pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Bacteraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Bacterial infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Blindness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Everolimus Blood albumin decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Blood alkaline phosphatase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Blood bilirubin increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Blood cholesterol increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Everolimus Blood creatine phosphokinase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Blood creatinine increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Blood lactate dehydrogenase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Blood potassium decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Blood pressure decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Blood sodium decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Blood urea increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Blood uric acid increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Body temperature decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Body temperature increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Everolimus Bone marrow failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Brain oedema 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Everolimus Breast cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Burning sensation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Everolimus C-reactive protein increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Cachexia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Cardiac disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Cardiac failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Cardiac failure acute 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Cardiac failure congestive 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Cardiogenic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Cardiopulmonary failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Cardiovascular disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Everolimus Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Cerebral haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Cerebral infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Cerebral ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Cerebrovascular accident 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Chest pain 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Choking 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Cholangitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Cholecystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Cholecystitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Cholestasis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Chromaturia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Chronic kidney disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Chronic obstructive pulmonary disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Circulatory collapse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Clostridium difficile colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Clostridium difficile infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Coagulopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Cognitive disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Everolimus Colitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Coma 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Everolimus Confusional state 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Congestive cardiomyopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Conjunctivitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Constipation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Coronary artery disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Cough 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Cyanosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Everolimus Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Decreased appetite 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Decubitus ulcer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Deep vein thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Dehydration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Delirium 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Dementia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Depressed level of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Depressed mood 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Depression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Dermatitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Diabetic ketoacidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Diarrhoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Diplopia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Disease recurrence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Disorientation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Disseminated intravascular coagulation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Diverticulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Dizziness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Drug eruption 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Everolimus Drug intolerance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Dysarthria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Dysmenorrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Everolimus Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Everolimus Dysphagia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Dysphonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Dyspnoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Dyspnoea exertional 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Dysstasia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Dysuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Ear pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Eating disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Eczema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Ejection fraction decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Electrocardiogram abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Electrolyte imbalance 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Enteritis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Enterocolitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Epistaxis 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Everolimus Erythema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Everolimus Facial paralysis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Everolimus Faeces discoloured 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Fatigue 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Fear 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Febrile neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Feeling abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Femur fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Flank pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Fluid overload 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Fluid retention 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Folliculitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Everolimus Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Full blood count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Fungal infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Gait disturbance 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Gallbladder disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Gamma-glutamyltransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Gastric disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Gastric haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Gastric ulcer 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Gastritis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Gastrointestinal haemorrhage 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Generalised oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Gout 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Haematemesis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Haematochezia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Haematocrit decreased 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Everolimus Haematoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Haematuria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Haemodynamic instability 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Haemoglobin decreased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Haemoptysis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Haemorrhage intracranial 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Haemorrhoids 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Headache 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Heart rate decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Hemiparesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Hepatic cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Hepatic cirrhosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Hepatic encephalopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Hepatic enzyme abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Hepatic function abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Hepatitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Hepatocellular injury 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Everolimus Hepatomegaly 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Hernia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Herpes zoster 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Hip fracture 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Everolimus Hydronephrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Hyperbilirubinaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Hypercalcaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Hyperglycaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Hyperkalaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Hyperlipidaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Hypernatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Hypertensive crisis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Hyperthermia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Hyperthyroidism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Everolimus Hypertriglyceridaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Hyperuricaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Hypoaesthesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Hypoalbuminaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Hypocalcaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Hypoglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Hypokalaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Hypokinesia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Hypomagnesaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Hyponatraemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Hypophagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Hypophosphataemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Hypotension 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Hypothyroidism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Hypovolaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Hypoxia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Ileus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Incontinence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Infection 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Inflammation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Influenza 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Interstitial lung disease 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Intestinal perforation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Iron deficiency anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Ischaemic stroke 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Jaundice 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Everolimus Jaundice cholestatic 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Joint swelling 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Large intestine perforation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Left ventricular dysfunction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Lethargy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Leukocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Lipase increased 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Everolimus Liver disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Liver function test abnormal 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Everolimus Liver injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Loss of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Lower respiratory tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Lung disorder 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Lung infection 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Lung infiltration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Lymphadenopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Lymphocyte count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Lymphoedema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Everolimus Lymphoma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Lymphopenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Everolimus Malaise 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Malnutrition 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Melaena 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Menorrhagia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Everolimus Menstruation irregular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Everolimus Mental disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Mental status changes 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Metabolic acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Metabolic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Metastases to central nervous system 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Metastases to liver 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Metastases to lung 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Metastatic neoplasm 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Metrorrhagia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Everolimus Migraine 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Everolimus Mitral valve incompetence 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Mobility decreased 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Everolimus Mood altered 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Mucosal inflammation 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Everolimus Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Muscle spasms 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Everolimus Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Musculoskeletal chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Myelodysplastic syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Nail disorder 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Everolimus Nasopharyngitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Everolimus Nausea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Neoplasm 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Everolimus Neoplasm progression 1.0 1.0 0.0 0.0 0.0 0.0 1.0 Everolimus Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Nervous system disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Everolimus Neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Obstructive airways disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Oedema 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Everolimus Oedema peripheral 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Oesophageal ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Oesophagitis 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Everolimus Oral candidiasis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Oral discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Osteonecrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Everolimus Osteonecrosis of jaw 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Everolimus Oxygen saturation decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Pain in jaw 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Everolimus Pallor 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Palpitations 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Everolimus Pancreatic carcinoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Pericardial effusion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Periorbital oedema 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Everolimus Peripheral sensory neuropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Everolimus Peripheral swelling 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Peritonitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Petechiae 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Pharyngitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Phlebitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Photophobia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Pigmentation disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Plasma cell myeloma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Platelet count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Pleural effusion 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Pleurisy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Pneumocystis jirovecii pneumonia 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Everolimus Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Pneumonia aspiration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Pneumonia bacterial 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Pneumonitis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Pneumothorax 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Polyneuropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Everolimus Polyuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Productive cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Protein urine present 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Everolimus Psychotic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Pulmonary alveolar haemorrhage 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Everolimus Pulmonary congestion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Pulmonary embolism 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Pulmonary fibrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Everolimus Pulmonary haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Pulmonary hypertension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Pulmonary oedema 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Pyelonephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Pyrexia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Rales 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Rash generalised 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Rash maculo-papular 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Everolimus Rash pruritic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Everolimus Red blood cell count decreased 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Everolimus Renal disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Renal failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Renal impairment 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Renal tubular necrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Respiratory disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Respiratory distress 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Respiratory tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Restlessness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Rhabdomyolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Rhinorrhoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Everolimus Sepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Sinus congestion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Everolimus Sinus tachycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Sinusitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Everolimus Skin discolouration 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Skin disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Skin reaction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Skin ulcer 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Everolimus Small intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Somnolence 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Everolimus Speech disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Everolimus Squamous cell carcinoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Staphylococcal infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Stomatitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Stress 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Subarachnoid haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Swelling face 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Swollen tongue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Syncope 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Tachycardia 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Everolimus Tachypnoea 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Everolimus Thirst 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Throat irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Everolimus Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Tinnitus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Tongue oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Treatment failure 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Everolimus Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Tubulointerstitial nephritis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Tumour lysis syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Unevaluable event 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Unresponsive to stimuli 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Upper gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Urinary retention 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Urinary tract infection 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Urine output decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Urosepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Urticaria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Everolimus Ventricular extrasystoles 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Ventricular fibrillation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Everolimus Vision blurred 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Visual acuity reduced 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Everolimus Vomiting 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Everolimus Weight decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Weight increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus Wheezing 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Everolimus White blood cell count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Everolimus White blood cell count increased 1.0 0.0 1.0 1.0 0.0 0.0 0.0 Exemestane Abdominal pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Exemestane Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Exemestane Anaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Exemestane Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Exemestane Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Exemestane Asthenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Exemestane Atrial fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Exemestane Breast cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Exemestane Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Exemestane Cerebral infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Exemestane Cholelithiasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Exemestane Chronic obstructive pulmonary disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Exemestane Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Exemestane Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Exemestane Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Exemestane Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Exemestane Dehydration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Exemestane Dementia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Exemestane Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Exemestane Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Exemestane Disturbance in attention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Exemestane Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Exemestane Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Exemestane Dyspepsia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Exemestane Dysphagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Exemestane Dyspnoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Exemestane Erythema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Exemestane Gamma-glutamyltransferase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Exemestane Haemoptysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Exemestane Hepatitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Exemestane Herpes zoster 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Exemestane Hypercholesterolaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Exemestane Hyperhidrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Exemestane Hypotension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Exemestane Hypothyroidism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Exemestane Influenza like illness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Exemestane Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Exemestane Lymphoedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Exemestane Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Exemestane Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Exemestane Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Exemestane Muscle spasms 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Exemestane Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Exemestane Neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Exemestane Neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Exemestane Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Exemestane Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Exemestane Oropharyngeal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Exemestane Osteonecrosis of jaw 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Exemestane Osteoporosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Exemestane Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Exemestane Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Exemestane Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Exemestane Platelet count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Exemestane Pleural effusion 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Exemestane Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Exemestane Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Exemestane Pulmonary embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Exemestane Pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Exemestane Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Exemestane Rash 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Exemestane Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Exemestane Sepsis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Exemestane Sinusitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Exemestane Somnolence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Exemestane Stomatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Exemestane Thrombocytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Exemestane Transaminases increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Exemestane Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Exemestane Vaginal haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Exemestane Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Exemestane Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Exemestane Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Exenatide Abdominal distension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Exenatide Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Exenatide Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Exenatide Asthenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Exenatide Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Exenatide Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Exenatide Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Exenatide Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Exenatide Hypoglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Exenatide Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Exenatide Pancreatitis acute 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Exenatide Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Exenatide Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ezetimibe Abasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ezetimibe Abdominal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ezetimibe Abdominal distension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ezetimibe Abdominal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ezetimibe Abdominal pain upper 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ezetimibe Acute myocardial infarction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ezetimibe Anaphylactic reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ezetimibe Angina pectoris 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ezetimibe Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ezetimibe Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ezetimibe Arthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ezetimibe Aspartate aminotransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ezetimibe Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ezetimibe Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ezetimibe Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ezetimibe Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ezetimibe Cardiac disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ezetimibe Cerebrovascular accident 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ezetimibe Cholecystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ezetimibe Chromaturia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ezetimibe Constipation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ezetimibe Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ezetimibe Death 1.0 0.0 0.0 1.0 1.0 0.0 0.0 Ezetimibe Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ezetimibe Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ezetimibe Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ezetimibe Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ezetimibe Drug-induced liver injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ezetimibe Dry mouth 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ezetimibe Dysphagia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ezetimibe Dyspnoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ezetimibe Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ezetimibe Erythema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ezetimibe Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ezetimibe Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ezetimibe Flatulence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ezetimibe Gait disturbance 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ezetimibe Gamma-glutamyltransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ezetimibe Gastrooesophageal reflux disease 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ezetimibe Gingival bleeding 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ezetimibe Glossodynia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ezetimibe Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ezetimibe Hepatic function abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ezetimibe Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ezetimibe Immune thrombocytopenic purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ezetimibe Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ezetimibe Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ezetimibe Interstitial lung disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ezetimibe Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ezetimibe Liver function test abnormal 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ezetimibe Loss of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ezetimibe Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ezetimibe Movement disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ezetimibe Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ezetimibe Muscle twitching 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ezetimibe Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ezetimibe Musculoskeletal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ezetimibe Musculoskeletal stiffness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ezetimibe Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ezetimibe Myocardial infarction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ezetimibe Myopathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ezetimibe Myositis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ezetimibe Nasopharyngitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ezetimibe Nausea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ezetimibe Neck pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ezetimibe Neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ezetimibe Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ezetimibe Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ezetimibe Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ezetimibe Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Ezetimibe Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ezetimibe Pneumonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ezetimibe Pruritus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ezetimibe Rash 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ezetimibe Renal failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ezetimibe Restlessness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ezetimibe Rhabdomyolysis 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Ezetimibe Suicidal ideation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ezetimibe Swollen tongue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ezetimibe Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ezetimibe Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ezetimibe Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ezetimibe Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ezetimibe Vomiting 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ezetimibe Weight decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Famciclovir Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Famotidine Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Famotidine Acute myocardial infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Famotidine Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Famotidine Atrioventricular block first degree 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Famotidine Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Famotidine Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Famotidine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Famotidine Depression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Famotidine Drug abuse 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Famotidine Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Famotidine Erythema multiforme 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Famotidine Fatigue 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Famotidine Feeling abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Famotidine Hypocalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Famotidine Hypomagnesaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Famotidine Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Famotidine Malaise 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Famotidine Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Famotidine Ventricular tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Famotidine Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Febuxostat Acute kidney injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Febuxostat Acute myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Febuxostat Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Febuxostat Atrial fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Febuxostat Blood creatinine increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Febuxostat Cardiac disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Febuxostat Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Febuxostat Cardiac failure congestive 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Febuxostat Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Febuxostat Chronic kidney disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Febuxostat Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Febuxostat Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Febuxostat Drug eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Febuxostat Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Febuxostat Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Febuxostat Erythema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Febuxostat Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Febuxostat Gout 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Febuxostat Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Febuxostat Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Febuxostat Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Febuxostat Myocardial infarction 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Febuxostat Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Febuxostat Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Febuxostat Pancytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Febuxostat Platelet count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Febuxostat Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Febuxostat Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Febuxostat Renal failure 1.0 0.0 0.0 0.0 0.0 1.0 0.0 Febuxostat Skin disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Febuxostat Stevens-Johnson syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Febuxostat Stomatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Febuxostat Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Febuxostat Transient ischaemic attack 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Febuxostat Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Febuxostat Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Felodipine Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Felodipine Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Felodipine Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Felodipine Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Felodipine Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Felodipine Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fenofibrate Abdominal pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fenofibrate Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Fenofibrate Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fenofibrate Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fenofibrate Arthralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fenofibrate Asthenia 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Fenofibrate Atrial fibrillation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fenofibrate Blister 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fenofibrate Cholecystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fenofibrate Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fenofibrate Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fenofibrate Chromaturia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fenofibrate Chronic kidney disease 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fenofibrate Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fenofibrate Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fenofibrate Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fenofibrate Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fenofibrate Drug intolerance 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fenofibrate Drug reaction with eosinophilia and systemic symptoms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fenofibrate Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fenofibrate Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fenofibrate Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fenofibrate Eosinophilia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fenofibrate Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fenofibrate Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fenofibrate Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fenofibrate Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fenofibrate Hepatic function abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fenofibrate Hepatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fenofibrate Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fenofibrate Hepatotoxicity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fenofibrate Herpes zoster 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fenofibrate Hyperglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fenofibrate Hypernatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fenofibrate Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fenofibrate Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fenofibrate Immune thrombocytopenic purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fenofibrate Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fenofibrate Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fenofibrate Jaundice cholestatic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fenofibrate Liver disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fenofibrate Liver function test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fenofibrate Loss of consciousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fenofibrate Lung disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fenofibrate Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fenofibrate Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fenofibrate Myalgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fenofibrate Myocardial infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fenofibrate Myositis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fenofibrate Nausea 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Fenofibrate Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fenofibrate Pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fenofibrate Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fenofibrate Pancreatic carcinoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fenofibrate Pancreatitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Fenofibrate Pancreatitis acute 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Fenofibrate Pruritus 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fenofibrate Pulmonary embolism 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fenofibrate Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fenofibrate Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fenofibrate Rash erythematous 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fenofibrate Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fenofibrate Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fenofibrate Renal failure 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Fenofibrate Renal impairment 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fenofibrate Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fenofibrate Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fenofibrate Septic shock 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fenofibrate Somnolence 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Fenofibrate Suicide attempt 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fenofibrate Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fenofibrate Visual impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fenofibrate Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Abdominal distension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Abdominal pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Abdominal pain upper 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Acidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Acute kidney injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Aggression 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Agitation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fentanyl Altered state of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Amnesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fentanyl Anaemia 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Fentanyl Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Angina pectoris 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Anuria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Apnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fentanyl Arthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fentanyl Arthropathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Aspartate aminotransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Atrial fibrillation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fentanyl Balance disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fentanyl Blood glucose increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Blood pressure decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Bone disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fentanyl Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Brain injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Brain oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Burning sensation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fentanyl Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Cardiac disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Cerebral ischaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Cerebrovascular accident 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fentanyl Cheilitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Chest discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fentanyl Chest pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Chronic obstructive pulmonary disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Circulatory collapse 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fentanyl Cognitive disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fentanyl Colon cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Confusional state 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Constipation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Cyanosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Cyst 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Decubitus ulcer 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fentanyl Deep vein thrombosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fentanyl Dehydration 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Depressed level of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fentanyl Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Disorientation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Disturbance in attention 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Drug dependence 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Fentanyl Drug hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fentanyl Drug interaction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Drug intolerance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Dry eye 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Dry mouth 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Dysarthria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Dysgeusia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fentanyl Dysphagia 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Fentanyl Dyspnoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Ecchymosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Electrocardiogram QT prolonged 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Emotional distress 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fentanyl Erythema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fentanyl Extrasystoles 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Eye disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Faecaloma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Feeling cold 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fentanyl Feeling hot 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fentanyl Fungal infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fentanyl Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Gastrooesophageal reflux disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Generalised tonic-clonic seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Glossitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Haemoptysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fentanyl Heart rate increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Hyperaesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fentanyl Hypercalcaemia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fentanyl Hyperglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Hypoglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Hypothermia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Hypoxia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Ileus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fentanyl Infection 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Fentanyl Inflammation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Influenza 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fentanyl Insomnia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Intestinal obstruction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Irritability 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Laryngospasm 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Leukocytosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Libido decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fentanyl Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Lung disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Malnutrition 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Mania 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fentanyl Mental disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Mental status changes 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Metabolic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Metastatic neoplasm 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Miosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Mucosal inflammation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Muscle rigidity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Muscle spasms 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fentanyl Muscular weakness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fentanyl Musculoskeletal stiffness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fentanyl Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Myocardial ischaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Myoclonus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Neck pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Nervousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fentanyl Neurotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fentanyl Ocular hyperaemia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fentanyl Oral candidiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Osteoarthritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Oxygen saturation decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Palpitations 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Pancreatic carcinoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Pancytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Panic attack 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fentanyl Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fentanyl Paranoia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fentanyl Platelet count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Pleural effusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Pneumonia aspiration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fentanyl Psychotic disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Pulmonary alveolar haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Pulmonary congestion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Pulmonary haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Pyrexia 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Fentanyl Rash 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fentanyl Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Respiratory depression 1.0 1.0 0.0 0.0 0.0 1.0 0.0 Fentanyl Respiratory disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Respiratory distress 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Respiratory failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Restlessness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Rhabdomyolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Serotonin syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Shock 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Sinus tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Skin lesion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Somnolence 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Speech disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fentanyl Subdural haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Suicidal ideation 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Fentanyl Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Tachycardia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fentanyl Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Thrombophlebitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fentanyl Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fentanyl Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Unresponsive to stimuli 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Upper respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Urinary retention 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl Weight decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fentanyl citrate Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl citrate Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl citrate Acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl citrate Anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl citrate Apnoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fentanyl citrate Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl citrate Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl citrate Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl citrate Chest pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl citrate Constipation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl citrate Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl citrate Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl citrate Dizziness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl citrate Drug hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fentanyl citrate Dry mouth 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl citrate Dyspnoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl citrate Euphoric mood 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fentanyl citrate Gait disturbance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fentanyl citrate Haemoptysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl citrate Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fentanyl citrate Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl citrate Malaise 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl citrate Mucosal inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl citrate Muscle rigidity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl citrate Muscular weakness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fentanyl citrate Nausea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl citrate Neck pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl citrate Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl citrate Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl citrate Pneumothorax 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl citrate Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fentanyl citrate Pyrexia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl citrate Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl citrate Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fentanyl citrate Respiratory depression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl citrate Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl citrate Restlessness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl citrate Seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl citrate Sepsis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl citrate Somnolence 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl citrate Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fentanyl citrate Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fentanyl citrate Vomiting 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ferric carboxymaltose Abasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Abdominal pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ferric carboxymaltose Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ferric carboxymaltose Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Arthralgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Back pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Blood pressure decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ferric carboxymaltose Blood pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ferric carboxymaltose Bone pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Chest discomfort 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Chest pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Chills 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Cold sweat 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ferric carboxymaltose Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ferric carboxymaltose Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ferric carboxymaltose Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Dyspnoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Emotional distress 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ferric carboxymaltose Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Feeling abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Feeling hot 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ferric carboxymaltose Flushing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ferric carboxymaltose Gait disturbance 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ferric carboxymaltose Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ferric carboxymaltose Hypertension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Hypoaesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Hypophosphataemia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ferric carboxymaltose Ill-defined disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Influenza like illness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Injection site pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ferric carboxymaltose Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ferric carboxymaltose Malaise 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Migraine 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Muscle spasms 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Muscle tightness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Muscular weakness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Myalgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Nausea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Oedema peripheral 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Oxygen saturation decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ferric carboxymaltose Pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Pain in extremity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Palpitations 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Paraesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Phlebitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ferric carboxymaltose Presyncope 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Pruritus 0.0 1.0 0.0 0.0 0.0 1.0 1.0 Ferric carboxymaltose Pruritus generalised 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ferric carboxymaltose Rash 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Ferric carboxymaltose Rash generalised 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ferric carboxymaltose Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ferric carboxymaltose Skin discolouration 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Ferric carboxymaltose Swelling 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Syncope 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Tachycardia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Throat tightness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ferric carboxymaltose Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Tremor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ferric carboxymaltose Vertigo 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Vision blurred 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Vomiting 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ferric carboxymaltose Wheezing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ferrous sulfate Acute hepatic failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ferrous sulfate Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ferrous sulfate Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fesoterodine fumarate Abdominal pain upper 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fesoterodine fumarate Back pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fesoterodine fumarate Dry eye 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fesoterodine fumarate Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fesoterodine fumarate Dysuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fesoterodine fumarate Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fesoterodine fumarate Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fexofenadine hydrochloride Back pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fexofenadine hydrochloride Diarrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fexofenadine hydrochloride Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fexofenadine hydrochloride Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Fexofenadine hydrochloride Headache 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Fexofenadine hydrochloride Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fexofenadine hydrochloride Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fexofenadine hydrochloride Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fexofenadine hydrochloride Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fexofenadine hydrochloride Nervousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fexofenadine hydrochloride Nightmare 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fexofenadine hydrochloride Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fexofenadine hydrochloride Sleep disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fexofenadine hydrochloride Somnolence 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Fidaxomicin Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fidaxomicin Clostridium difficile infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fidaxomicin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fidaxomicin Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fidaxomicin Dysphagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fidaxomicin Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fidaxomicin Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Finasteride Abdominal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Abdominal distension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Abdominal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Abdominal pain lower 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Abdominal pain upper 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Abnormal faeces 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Acne 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Acute kidney injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Finasteride Aggression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Finasteride Agitation 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Alanine aminotransferase increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Amnesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Finasteride Anaemia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Anaphylactic shock 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Anger 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Angina pectoris 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Angioedema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Angiopathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Apathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Aphasia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Finasteride Arrhythmia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Finasteride Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Arthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Arthropathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Aspartate aminotransferase increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Finasteride Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Asthma 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Atrial fibrillation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Finasteride Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Bacterial infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Balance disorder 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Basal cell carcinoma 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Blepharitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Blood alkaline phosphatase increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Finasteride Blood bilirubin increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Finasteride Blood cholesterol increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Blood creatine phosphokinase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Finasteride Blood creatinine increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Blood glucose increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Blood pressure decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Finasteride Blood pressure increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Blood triglycerides increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Blood urine present 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Body temperature decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Bone disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Finasteride Bone pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Bradyphrenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Brain injury 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Finasteride Breast enlargement 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Breast pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Finasteride Bronchitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Burning sensation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Candida infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Cardiac disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Cardiac failure congestive 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Cardiac murmur 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Carpal tunnel syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Cataract 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Cellulitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Finasteride Cerebral infarction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Cerebrovascular accident 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Chest discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Chest pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Chills 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Cholelithiasis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Chronic obstructive pulmonary disease 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Cognitive disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Cold sweat 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Finasteride Colitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Completed suicide 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Finasteride Confusional state 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Conjunctivitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Finasteride Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Contusion 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Finasteride Coordination abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Coronary artery disease 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Cough 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Crying 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Finasteride Cyst 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Deafness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Finasteride Decreased appetite 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Finasteride Dehydration 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Depressed level of consciousness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Depressed mood 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Depression 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Finasteride Dermatitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Dermatitis contact 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Diabetes mellitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Diplopia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Finasteride Discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Disorientation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Disturbance in sexual arousal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Diverticulitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Drug abuse 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Drug dependence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Drug hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Drug intolerance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Drug withdrawal syndrome 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Dry eye 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Dry skin 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Dysarthria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Dyskinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Dysphagia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Dysphonia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Dyspnoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Dyspnoea exertional 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Dysstasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Finasteride Dysuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Ear pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Eating disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Eczema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Emotional disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Finasteride Emotional distress 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Endocrine disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Epistaxis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Erectile dysfunction 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Finasteride Erythema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Eye disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Eye pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Face oedema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Fear 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Feeling abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Finasteride Feeling cold 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Feeling hot 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Flank pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Flat affect 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Flatulence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Fluid retention 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Flushing 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Folliculitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Fracture 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Finasteride Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Gamma-glutamyltransferase increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Gastric disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Gastric ulcer 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Gastritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Gastroenteritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Gastrointestinal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Gastrooesophageal reflux disease 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Generalised tonic-clonic seizure 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Finasteride Gout 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Gynaecomastia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Haematochezia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Finasteride Haematuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Haemorrhoids 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Heart rate increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Heart rate irregular 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Hepatic enzyme increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Hepatic function abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Finasteride Hepatic steatosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Hepatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Finasteride Hepatomegaly 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Hernia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Herpes simplex 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Hot flush 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Hypercholesterolaemia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Hyperglycaemia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Hyperhidrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Hyperlipidaemia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Hypersomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Hypertension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Hypertriglyceridaemia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Hypoacusis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Hypotension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Hypothyroidism 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Hypotonia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Immune system disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Infection 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Finasteride Inflammation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Influenza 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Injury 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Intervertebral disc protrusion 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Irritability 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Irritable bowel syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Finasteride Joint stiffness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Joint swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Laceration 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Laryngitis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Finasteride Lethargy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Libido decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Libido increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Liver function test abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Loss of consciousness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Loss of libido 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Lymphadenopathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Mass 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Mental disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Mental impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Mental status changes 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Metabolic disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Micturition urgency 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Middle insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Mood altered 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Finasteride Mood swings 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Muscle atrophy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Muscle tightness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Muscle twitching 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Finasteride Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Musculoskeletal chest pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Musculoskeletal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Musculoskeletal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Musculoskeletal stiffness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Myocardial infarction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Myopathy 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Finasteride Myositis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Nasal congestion 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Nasopharyngitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Neck pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Necrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Neoplasm malignant 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Nephrolithiasis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Nervous system disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Nervousness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Finasteride Neuralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Neuritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Night sweats 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Finasteride Nightmare 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Nocturia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Obesity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Ocular hyperaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Finasteride Oedema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Oedema peripheral 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Finasteride Oral candidiasis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Oropharyngeal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Osteoarthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Osteoporosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Otitis media 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Palpitations 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Pancreatitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Finasteride Panic attack 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Paranoia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Pelvic pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Peripheral coldness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Peripheral sensory neuropathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Peripheral vascular disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Personality change 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Finasteride Personality disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Pharyngitis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Finasteride Photophobia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Pneumonia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Finasteride Pollakiuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Polyuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Poor quality sleep 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Presyncope 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Proctalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Productive cough 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Prostate cancer 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Prostatic disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Protein urine present 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Psoriasis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Psychotic disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Finasteride Pulmonary embolism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Finasteride Pulmonary mass 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Pyrexia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Finasteride Rash 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Rectal haemorrhage 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Renal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Renal failure 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Restless legs syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Restlessness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Rheumatoid arthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Rhinitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Rhinorrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Sciatica 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Seborrhoeic dermatitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Sedation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Seizure 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Finasteride Sensory disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Sensory loss 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Sexual dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Sinus bradycardia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Sinus congestion 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Sinus disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Sinusitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Skin burning sensation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Skin disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Skin exfoliation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Skin irritation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Skin lesion 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Sleep apnoea syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Sleep disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Somnolence 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Finasteride Speech disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Splenomegaly 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Finasteride Squamous cell carcinoma 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Staphylococcal infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Stress 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Suicidal ideation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Finasteride Suicide attempt 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Finasteride Supraventricular extrasystoles 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Supraventricular tachycardia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Finasteride Swelling face 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Finasteride Tachycardia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Tendon rupture 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Tendonitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Thinking abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Thirst 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Thrombosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Tinnitus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Finasteride Tongue discolouration 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Finasteride Transient ischaemic attack 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Finasteride Treatment failure 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Unevaluable event 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Upper limb fracture 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Upper respiratory tract infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Urinary incontinence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Urinary retention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Urinary tract disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Urinary tract infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Urticaria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Varicose vein 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Ventricular extrasystoles 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Finasteride Vertigo 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Viral infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Visual acuity reduced 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Vomiting 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Weight decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride Wheezing 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Finasteride White blood cell count decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fingolimod Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fingolimod Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fingolimod Disease recurrence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod Dysphagia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fingolimod Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fingolimod Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fingolimod Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fingolimod Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fingolimod Muscular weakness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod Myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fingolimod Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fingolimod Nervous system disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fingolimod Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fingolimod Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fingolimod Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fingolimod Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fingolimod Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fingolimod Urosepsis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fingolimod Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fingolimod hydrochloride Alanine aminotransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod hydrochloride Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod hydrochloride Angiopathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod hydrochloride Aspartate aminotransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod hydrochloride Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Fingolimod hydrochloride Atrioventricular block 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod hydrochloride Atrioventricular block complete 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fingolimod hydrochloride Atrioventricular block second degree 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fingolimod hydrochloride Back pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod hydrochloride Blood disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod hydrochloride Blood triglycerides increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod hydrochloride Bradycardia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod hydrochloride Bronchitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod hydrochloride Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fingolimod hydrochloride Cardiac disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fingolimod hydrochloride Cerebral haemorrhage 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fingolimod hydrochloride Cerebrovascular accident 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fingolimod hydrochloride Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod hydrochloride Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fingolimod hydrochloride Depressed mood 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Fingolimod hydrochloride Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod hydrochloride Diarrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod hydrochloride Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod hydrochloride Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fingolimod hydrochloride Eczema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod hydrochloride Eye disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod hydrochloride Eye pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod hydrochloride Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod hydrochloride Gamma-glutamyltransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod hydrochloride Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod hydrochloride Hepatic enzyme increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod hydrochloride Herpes zoster 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod hydrochloride Hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod hydrochloride Hypotension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod hydrochloride Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fingolimod hydrochloride Influenza 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod hydrochloride Ischaemic stroke 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Fingolimod hydrochloride Leukopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod hydrochloride Liver function test abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod hydrochloride Liver injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fingolimod hydrochloride Lower respiratory tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod hydrochloride Lymphopenia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Fingolimod hydrochloride Mental disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fingolimod hydrochloride Migraine 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod hydrochloride Nervous system disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fingolimod hydrochloride Neutrophil count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod hydrochloride Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod hydrochloride Paraesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod hydrochloride Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fingolimod hydrochloride Posterior reversible encephalopathy syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fingolimod hydrochloride Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod hydrochloride Sinusitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod hydrochloride Skin disorder 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Fingolimod hydrochloride Viral infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fingolimod hydrochloride Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Fingolimod hydrochloride Visual acuity reduced 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Fingolimod hydrochloride Weight decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Flecainide Acute kidney injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Flecainide Arrhythmia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Flecainide Asthenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Flecainide Ataxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Flecainide Atrial fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Flecainide Atrial flutter 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Flecainide Atrioventricular block 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Flecainide Atrioventricular block first degree 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Flecainide Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Flecainide Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Flecainide Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Flecainide Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Flecainide Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Flecainide Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Flecainide Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Flecainide Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Flecainide Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Flecainide Electrocardiogram abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Flecainide Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Flecainide Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Flecainide Interstitial lung disease 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Flecainide Lethargy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Flecainide Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Flecainide Metabolic acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Flecainide Myalgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Flecainide Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Flecainide Pulmonary alveolar haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Flecainide Pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Flecainide Renal failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Flecainide Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Flecainide Shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Flecainide Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Flecainide Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Flecainide Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Flecainide Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Flecainide Torsade de pointes 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Flecainide Unresponsive to stimuli 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Flecainide Ventricular fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Flecainide Ventricular tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Flecainide Vomiting 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Flecainide acetate Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Flecainide acetate Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Flecainide acetate Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Abdominal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluconazole Abdominal pain lower 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluconazole Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluconazole Acute generalised exanthematous pustulosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluconazole Acute hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluconazole Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Alanine aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluconazole Altered state of consciousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluconazole Anaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluconazole Arrhythmia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Arthralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluconazole Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluconazole Ataxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluconazole Atrial fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Atrial septal defect 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Fluconazole Balance disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluconazole Blister 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluconazole Blood alkaline phosphatase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluconazole Blood pressure increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Body temperature decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluconazole Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole C-reactive protein increased 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluconazole Candida infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Cardiac failure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluconazole Cerebral infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Chest pain 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluconazole Coma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Confusional state 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Constipation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluconazole Cough 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluconazole Cyanosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Decreased appetite 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluconazole Dermatitis contact 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluconazole Diarrhoea 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluconazole Disease progression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluconazole Drug eruption 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluconazole Drug hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluconazole Drug interaction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluconazole Drug reaction with eosinophilia and systemic symptoms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluconazole Drug resistance 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Drug-induced liver injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Dysphagia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Dyspnoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fluconazole Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Eosinophilia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluconazole Eye swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluconazole Face oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluconazole Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluconazole Febrile neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluconazole Flushing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluconazole Fungal infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluconazole Haemoptysis 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluconazole Haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Hepatic encephalopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Hepatitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluconazole Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluconazole Hepatotoxicity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Hypercalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluconazole Hypercholesterolaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluconazole Hyperkalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluconazole Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluconazole Hypokalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Hypomagnesaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluconazole Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Hypoxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Insomnia 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluconazole Jaundice 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluconazole Lethargy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Lip swelling 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Fluconazole Liver function test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluconazole Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Lymphadenopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluconazole Malnutrition 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Metrorrhagia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluconazole Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Nervous system disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Oral pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluconazole Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluconazole Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluconazole Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluconazole Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Paraesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fluconazole Pericarditis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluconazole Peripheral sensory neuropathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluconazole Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluconazole Pigmentation disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluconazole Platelet count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluconazole Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluconazole Pruritus generalised 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluconazole Pulmonary alveolar haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Pulmonary embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluconazole Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Rash generalised 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Fluconazole Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluconazole Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluconazole Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluconazole Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Skin burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluconazole Somnolence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluconazole Stevens-Johnson syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluconazole Swelling face 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Swollen tongue 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Fluconazole Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Tinnitus 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluconazole Torsade de pointes 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Toxic epidermal necrolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Treatment failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Urinary incontinence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Urinary tract infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluconazole Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Vascular purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluconazole Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluconazole Visual impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluconazole Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Acute myeloid leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Acute respiratory distress syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fludarabine phosphate Bone marrow failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Cardiac failure congestive 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Coma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Confusional state 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Depression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Diarrhoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Dyspnoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Haemoglobin decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Headache 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Herpes zoster 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fludarabine phosphate Hypoxia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Interstitial lung disease 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Leukopenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Mucosal inflammation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Myelodysplastic syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Neuropathy peripheral 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Neurotoxicity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Platelet count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Pulmonary haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Pyrexia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Respiratory distress 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fludarabine phosphate Sinusitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fludarabine phosphate Tumour lysis syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Flumazenil Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluocinolone acetonide Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluocinolone acetonide Intraocular pressure increased 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Fluocinolone acetonide Visual acuity reduced 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluocinolone acetonide Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluorescein sodium Anaphylactic reaction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorescein sodium Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fluorescein sodium Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorescein sodium Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorescein sodium Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorescein sodium Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorescein sodium Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Abdominal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Abdominal distension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Abdominal pain lower 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Abdominal tenderness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Acute coronary syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Acute hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Acute myeloid leukaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Acute myocardial infarction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Acute pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Acute respiratory failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Agranulocytosis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Angina pectoris 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Aphasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Aphthous ulcer 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluorouracil Arrhythmia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Ascites 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Aspartate aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Asthenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Ataxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Atrial fibrillation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Blepharitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluorouracil Blood alkaline phosphatase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Blood urea increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Bone marrow failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluorouracil Bronchospasm 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Burning sensation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Cardiac failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Cardiac failure acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Cardiogenic shock 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Cardiomyopathy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Cardiotoxicity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Cerebral ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Cerebrovascular accident 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Chest discomfort 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Chest pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Chills 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Clostridium difficile colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Colitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Congestive cardiomyopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Crohn's disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluorouracil Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Decreased appetite 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Deep vein thrombosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Dermatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluorouracil Diarrhoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Diplopia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Disseminated intravascular coagulation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Drug intolerance 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Fluorouracil Drug resistance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluorouracil Drug-induced liver injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluorouracil Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluorouracil Dysaesthesia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Dyspnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Dyspnoea exertional 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Ejection fraction decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Encephalopathy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Enteritis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Enterocolitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Eructation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Extravasation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluorouracil Eye irritation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Febrile neutropenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Flatulence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Gastric ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Haemoglobin decreased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Haemorrhoids 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Headache 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Hiccups 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Hyperthermia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Hypoaesthesia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Hypotension 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Hypoxia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Ileus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Interstitial lung disease 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Intestinal perforation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Ischaemic stroke 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Jaundice 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Lacrimation increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Lactic acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Laryngeal oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Left ventricular dysfunction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Leukocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Fluorouracil Liver injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluorouracil Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Lung disorder 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Malaise 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Melaena 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Metabolic acidosis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Metastases to liver 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluorouracil Metastases to lung 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Mouth ulceration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Mucosal inflammation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Muscular weakness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Myocardial ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Myocarditis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Neck pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Neoplasm progression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Neuralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluorouracil Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluorouracil Neurotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluorouracil Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Fluorouracil Neutrophil count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Oedema peripheral 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Oesophagitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Oropharyngeal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Osteonecrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Oxygen saturation decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Pancytopenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Paraesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluorouracil Peripheral sensory neuropathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluorouracil Photosensitivity reaction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Pigmentation disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluorouracil Platelet count decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Pleural effusion 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Pneumonitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Posterior reversible encephalopathy syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Pulmonary alveolar haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Pulmonary embolism 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Pulmonary fibrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Pulmonary oedema 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluorouracil Rash pustular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluorouracil Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Renal failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Renal tubular necrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Respiratory distress 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Sepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Skin reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluorouracil Small intestinal obstruction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Squamous cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluorouracil Staphylococcal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Stomatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Stress cardiomyopathy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Supraventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Syncope 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Tachycardia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Tenderness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Thrombophlebitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Treatment failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Tremor 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluorouracil Tumour lysis syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Upper respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Urinary tract infection 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Varicose vein 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Ventricular fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluorouracil Ventricular tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluorouracil Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil White blood cell count decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluorouracil White blood cell count increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluoxetine hydrochloride Abnormal dreams 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Fluoxetine hydrochloride Aggression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Agitation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Akathisia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Alopecia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Arrhythmia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluoxetine hydrochloride Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Ataxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fluoxetine hydrochloride Atrial fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluoxetine hydrochloride Balance disorder 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Cardiac arrest 1.0 1.0 0.0 0.0 1.0 0.0 0.0 Fluoxetine hydrochloride Cataract 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Cerebrovascular accident 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Fluoxetine hydrochloride Chills 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Cognitive disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Constipation 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Fluoxetine hydrochloride Decreased appetite 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Fluoxetine hydrochloride Delusion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluoxetine hydrochloride Depersonalisation/derealisation disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Diarrhoea 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Fluoxetine hydrochloride Diarrhoea haemorrhagic 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluoxetine hydrochloride Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluoxetine hydrochloride Duodenal ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluoxetine hydrochloride Dyskinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Dyspepsia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Dysphagia 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Fluoxetine hydrochloride Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluoxetine hydrochloride Ecchymosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluoxetine hydrochloride Electrocardiogram QT prolonged 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluoxetine hydrochloride Epistaxis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluoxetine hydrochloride Erectile dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Euphoric mood 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Flatulence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluoxetine hydrochloride Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fluoxetine hydrochloride Gynaecomastia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluoxetine hydrochloride Haematemesis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluoxetine hydrochloride Headache 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Fluoxetine hydrochloride Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Hypersensitivity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Hypoglycaemia 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Fluoxetine hydrochloride Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluoxetine hydrochloride Hypotension 0.0 1.0 1.0 0.0 1.0 0.0 0.0 Fluoxetine hydrochloride Insomnia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Libido decreased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Melaena 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluoxetine hydrochloride Memory impairment 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Mydriasis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluoxetine hydrochloride Myoclonus 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluoxetine hydrochloride Nausea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Nervousness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Palpitations 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Pancreatitis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Pancytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluoxetine hydrochloride Paranoia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Pharyngitis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Photosensitivity reaction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluoxetine hydrochloride Pollakiuria 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Pulmonary hypertension 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Fluoxetine hydrochloride Pyrexia 0.0 1.0 1.0 1.0 1.0 0.0 0.0 Fluoxetine hydrochloride Renal failure 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Fluoxetine hydrochloride Seizure 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Fluoxetine hydrochloride Serotonin syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fluoxetine hydrochloride Sexual dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Sinusitis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Somnolence 0.0 1.0 1.0 0.0 1.0 0.0 0.0 Fluoxetine hydrochloride Stevens-Johnson syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluoxetine hydrochloride Suicidal ideation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Suicide attempt 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Thinking abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluoxetine hydrochloride Tremor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluoxetine hydrochloride Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Vomiting 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Fluoxetine hydrochloride Weight decreased 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Fluphenazine Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fluphenazine Neuroleptic malignant syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Flurbiprofen Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Flurbiprofen Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Flurbiprofen Dyspnoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Flurbiprofen Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluticasone Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone Dyspnoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluticasone Epistaxis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone Sinusitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone furoate Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluticasone furoate Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone furoate Chronic obstructive pulmonary disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluticasone furoate Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone furoate Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone furoate Dysphonia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone furoate Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluticasone furoate Epistaxis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone furoate Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluticasone furoate Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone furoate Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone furoate Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone furoate Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone propionate Abdominal distension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone propionate Ageusia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluticasone propionate Agitation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone propionate Anaphylactic reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone propionate Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluticasone propionate Arrhythmia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone propionate Asthma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluticasone propionate Blindness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone propionate Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluticasone propionate Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone propionate Choking 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone propionate Chronic obstructive pulmonary disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluticasone propionate Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone propionate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fluticasone propionate Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluticasone propionate Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone propionate Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluticasone propionate Drug hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone propionate Dysgeusia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fluticasone propionate Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone propionate Dysphonia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone propionate Dyspnoea 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Fluticasone propionate Ear pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone propionate Epistaxis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Fluticasone propionate Erythema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone propionate Eye pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone propionate Eye swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone propionate Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fluticasone propionate Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluticasone propionate Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone propionate Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluticasone propionate Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone propionate Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluticasone propionate Irritability 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone propionate Lower respiratory tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone propionate Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluticasone propionate Nasal congestion 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluticasone propionate Nasal dryness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone propionate Nausea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fluticasone propionate Ocular hyperaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone propionate Oropharyngeal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone propionate Oxygen saturation decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluticasone propionate Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluticasone propionate Parosmia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluticasone propionate Rash 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluticasone propionate Respiratory tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone propionate Rhinorrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone propionate Sinus disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone propionate Sinusitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluticasone propionate Swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone propionate Throat irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone propionate Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluticasone propionate Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluticasone propionate Vomiting 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluticasone propionate Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluticasone propionate Wheezing 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fluvastatin sodium Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluvastatin sodium Acute kidney injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluvastatin sodium Anxiety 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluvastatin sodium Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluvastatin sodium Atrial fibrillation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fluvastatin sodium Blood alkaline phosphatase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluvastatin sodium Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluvastatin sodium Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluvastatin sodium Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluvastatin sodium Gamma-glutamyltransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluvastatin sodium Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluvastatin sodium Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluvastatin sodium Hypoaesthesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluvastatin sodium Insomnia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluvastatin sodium Muscle spasms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluvastatin sodium Muscular weakness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluvastatin sodium Myalgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Fluvastatin sodium Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluvastatin sodium Oedema peripheral 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluvastatin sodium Paraesthesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluvastatin sodium Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluvastatin sodium Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluvastatin sodium Red blood cell sedimentation rate increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluvastatin sodium Rhabdomyolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluvastatin sodium Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluvastatin sodium Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluvoxamine Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluvoxamine Cardiac arrest 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluvoxamine Drug interaction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fluvoxamine Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluvoxamine Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fluvoxamine maleate Somnolence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fluvoxamine maleate Suicide attempt 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Folic acid Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Folic acid Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Folic acid Cerebrovascular accident 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Folic acid Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Folic acid Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Folic acid Diarrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Folic acid Dyspnoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Folic acid Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Folic acid Hepatic necrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Folic acid Joint swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Folic acid Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Folic acid Pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Folic acid Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Folic acid Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Folic acid Renal tubular necrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Folic acid Rheumatoid arthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fondaparinux Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fondaparinux Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fondaparinux Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fondaparinux Cerebral haemorrhage 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Fondaparinux Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fondaparinux Deep vein thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fondaparinux Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fondaparinux Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fondaparinux Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fondaparinux Haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fondaparinux Haemorrhage intracranial 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fondaparinux Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fondaparinux Hemiplegia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fondaparinux Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fondaparinux Melaena 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fondaparinux Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fondaparinux Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fondaparinux Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fondaparinux Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fondaparinux Shock haemorrhagic 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fondaparinux Subdural haematoma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fondaparinux Thrombosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fondaparinux sodium Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fondaparinux sodium Anaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fondaparinux sodium Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fondaparinux sodium Cerebral haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fondaparinux sodium Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fondaparinux sodium Drug interaction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fondaparinux sodium Haematoma 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Fondaparinux sodium Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fondaparinux sodium Haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fondaparinux sodium Haemorrhage intracranial 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fondaparinux sodium Haemorrhagic stroke 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fondaparinux sodium Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fondaparinux sodium Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fondaparinux sodium Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fondaparinux sodium Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fondaparinux sodium Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Formoterol Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Formoterol fumarate Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Formoterol fumarate Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Formoterol fumarate Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Formoterol fumarate Malaise 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Fosaprepitant dimeglumine Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fosaprepitant dimeglumine Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fosaprepitant dimeglumine Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fosaprepitant dimeglumine Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fosaprepitant dimeglumine Dyspnoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fosaprepitant dimeglumine Febrile neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fosaprepitant dimeglumine Flushing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fosaprepitant dimeglumine Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fosaprepitant dimeglumine Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Foscarnet sodium Acute kidney injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Foscarnet sodium Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Foscarnet sodium Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Foscarnet sodium Diarrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Foscarnet sodium Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Foscarnet sodium Hypocalcaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Foscarnet sodium Hypokalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Foscarnet sodium Hypophosphataemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Foscarnet sodium Hypotension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Foscarnet sodium Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Foscarnet sodium Nephropathy toxic 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Foscarnet sodium Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Foscarnet sodium Paraesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Foscarnet sodium Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Foscarnet sodium Pyrexia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Foscarnet sodium Renal impairment 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Foscarnet sodium Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Foscarnet sodium Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Foscarnet sodium Thrombocytopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Foscarnet sodium Vomiting 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fosfomycin tromethamine Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fosinopril Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fosinopril Angioedema 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Fosinopril Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fosinopril Hypertensive crisis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fosinopril Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fosinopril Paraesthesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fosinopril Swollen tongue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fosphenytoin Status epilepticus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fosphenytoin sodium Bradycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fosphenytoin sodium Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fosphenytoin sodium Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fosphenytoin sodium Encephalopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fosphenytoin sodium Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fosphenytoin sodium Hypoxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fostamatinib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fostamatinib Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fostamatinib Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fostamatinib Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fostamatinib Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fostamatinib Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fostamatinib Platelet count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fostamatinib Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fulvestrant Abdominal pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Acute kidney injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Alanine aminotransferase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Arthralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Aspartate aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Asthenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Atrial fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Back pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Blood bilirubin increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Blood pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Bone marrow failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Bone pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Cellulitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Fulvestrant Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fulvestrant Confusional state 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Constipation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Dehydration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Fulvestrant Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fulvestrant Drug hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Drug resistance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Dysgeusia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Dysphagia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Ejection fraction decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Erythema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Flushing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Fracture 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Gamma-glutamyltransferase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Gastrooesophageal reflux disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Haematemesis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Haemoglobin decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Hepatic cirrhosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Hepatic enzyme increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Hepatic function abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Herpes zoster 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Hip fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fulvestrant Hot flush 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Hydronephrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fulvestrant Hyperglycaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Hyperhidrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fulvestrant Hypokalaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fulvestrant Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fulvestrant Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Inflammation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Injection site pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Insomnia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Jaundice 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Lacrimation increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Leukopenia 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Liver disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Loss of consciousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Lymphoedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Metastases to central nervous system 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Metastases to liver 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Metastases to lung 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Mobility decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Musculoskeletal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Musculoskeletal pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Nausea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fulvestrant Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Pain in extremity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Fulvestrant Pleural effusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Pneumonitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Pneumothorax 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fulvestrant Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Pulmonary congestion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fulvestrant Pulmonary embolism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Fulvestrant Rash 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Renal failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Sciatica 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Swelling face 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Throat tightness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Urinary tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Fulvestrant Vomiting 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Fulvestrant Weight decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Fulvestrant White blood cell count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Abdominal discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Abscess 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Acidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Acute generalised exanthematous pustulosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Acute hepatic failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Acute kidney injury 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Furosemide Acute myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Acute pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Acute respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Agranulocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Alanine aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Furosemide Altered state of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Anaemia 0.0 1.0 1.0 0.0 1.0 0.0 0.0 Furosemide Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Anuria 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Apathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Aphasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Arthralgia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Ascites 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Asphyxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Furosemide Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Asthma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Ataxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Atrial fibrillation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Atrioventricular block 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Atrioventricular block complete 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Furosemide Bacteraemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Furosemide Balance disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Blister 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Blood albumin decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Furosemide Blood alkaline phosphatase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Blood bilirubin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Blood cholesterol increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Furosemide Blood creatine phosphokinase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Blood creatinine increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Blood glucose increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Blood lactate dehydrogenase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Furosemide Blood potassium decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Blood potassium increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Blood urea increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Blood urine present 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Body temperature decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Bone marrow failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Furosemide Bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Bradyphrenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Brain injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Furosemide Burning sensation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide C-reactive protein increased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Cardiac disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Cardiac failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Cardiac failure acute 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Cardiac failure congestive 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Cardiogenic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Cardiomyopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Furosemide Cerebral infarction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Furosemide Chest pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Chills 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Furosemide Cholecystitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Furosemide Cholestasis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Chronic kidney disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Chronic obstructive pulmonary disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Circulatory collapse 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Coagulopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Cognitive disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Colon cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Furosemide Coma 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Confusional state 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Contusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Cyanosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Deafness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Furosemide Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Furosemide Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Deep vein thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Dehydration 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Furosemide Delirium 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Depressed level of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Depression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Dermatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Furosemide Dermatitis bullous 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Dermatitis exfoliative 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Diarrhoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Disease recurrence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Disorientation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Disturbance in attention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Diverticulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Dizziness 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Furosemide Drug abuse 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Drug dependence 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Drug hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Drug interaction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Drug resistance 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Drug withdrawal syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Drug-induced liver injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Dysarthria 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Dysphonia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Furosemide Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Dyspnoea exertional 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Eczema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Ejection fraction decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Electrocardiogram abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Electrolyte imbalance 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Encephalopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Epilepsy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Epistaxis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Erythema 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Erythema multiforme 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Extrasystoles 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Furosemide Fatigue 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Febrile neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Feeling cold 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Fluid overload 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Fluid retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Foetal growth restriction 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Furosemide Gait disturbance 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Gamma-glutamyltransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Gastric haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Gastric ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Gastrooesophageal reflux disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Generalised oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Generalised tonic-clonic seizure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Granulocytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Furosemide Haematemesis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Furosemide Haematoma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Haemodynamic instability 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Haemolysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Furosemide Haemoptysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Furosemide Haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Hallucination, visual 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Headache 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Heart rate decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Hepatic encephalopathy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Hepatic enzyme increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Furosemide Hepatic function abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Hepatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Hepatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Hepatitis cholestatic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Hepatotoxicity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Hyperbilirubinaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Hypercalcaemia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Furosemide Hyperglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Hyperkalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Hypernatraemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Furosemide Hypersensitivity vasculitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Hypertensive crisis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Furosemide Hyperthermia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Hyperthyroidism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Furosemide Hyperuricaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Hypoacusis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Furosemide Hypoalbuminaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Hypocalcaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Hypokalaemia 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Furosemide Hypokinesia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Furosemide Hypomagnesaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Hyporeflexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Hypotension 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Furosemide Hypothermia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Hypotonia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Hypovolaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Hypoxia 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Furosemide Ileus paralytic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Immune thrombocytopenic purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Inappropriate antidiuretic hormone secretion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Injection site pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Intentional self-injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Interstitial lung disease 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Iron deficiency anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Irritability 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Ischaemic stroke 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Furosemide Jaundice 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Lactic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Left ventricular dysfunction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Leukocytosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Furosemide Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Liver function test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Liver injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Loss of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Lower respiratory tract infection 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Lung disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Lung infiltration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Lymphadenopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Furosemide Malnutrition 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Melaena 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Memory impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Mental impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Metabolic acidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Mitral valve incompetence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Mobility decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Musculoskeletal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Furosemide Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Furosemide Myocardial ischaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Furosemide Myoclonus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Myopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Neoplasm malignant 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Nephrolithiasis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Nephropathy toxic 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Nephrotic syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Nervous system disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Neutropenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Nocturia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Nystagmus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Oliguria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Oropharyngeal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Furosemide Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Osteoporosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Oxygen saturation decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Pain in extremity 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Palpitations 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Pancreatitis acute 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Pancytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Furosemide Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Furosemide Paralysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Parkinsonism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Platelet count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Pleural effusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Pneumonia aspiration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Pneumonitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Polyuria 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 1.0 Furosemide Premature delivery 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Proteinuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Pulmonary congestion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Pulmonary embolism 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Furosemide Pulmonary haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Pulmonary hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Pulmonary oedema 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Pyrexia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Rales 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Rash 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Rash erythematous 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Rash macular 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Furosemide Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Rash papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Rectal haemorrhage 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Red blood cell sedimentation rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Renal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Renal failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Renal impairment 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Respiratory disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Furosemide Respiratory distress 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Respiratory failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Respiratory tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Restlessness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Furosemide Retching 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Furosemide Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Seizure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Sepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Shock haemorrhagic 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Sinus bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Skin discolouration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Skin exfoliation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Furosemide Skin lesion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Furosemide Sleep disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Sluggishness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Somnolence 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Sopor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Speech disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Staphylococcal infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Status epilepticus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Furosemide Stevens-Johnson syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Furosemide Stomatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Subdural haematoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Furosemide Supraventricular extrasystoles 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Supraventricular tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Swelling face 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Throat irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Furosemide Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Tinnitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Furosemide Torsade de pointes 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Toxic epidermal necrolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Toxic skin eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Transient ischaemic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Troponin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Unresponsive to stimuli 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Urinary incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Urine output decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Vascular purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Ventricular extrasystoles 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Ventricular fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Furosemide Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Furosemide Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Weight increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Furosemide Wheezing 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Furosemide White blood cell count increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Abasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Abdominal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Abdominal distension 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Abdominal pain upper 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Abnormal dreams 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Abnormal faeces 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Acne 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Acute hepatic failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Acute respiratory failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Affect lability 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Ageusia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Aggression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Agitation 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Gabapentin Akathisia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Alopecia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Altered state of consciousness 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Amnesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Anal incontinence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Anger 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Angioedema 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Gabapentin Anorectal disorder 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Gabapentin Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Aphasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Arthralgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Arthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Arthropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Aspartate aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Asphyxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Asthenia 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Gabapentin Asthma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Ataxia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Atrial fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Atrial septal defect 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Gabapentin Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Balance disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Blindness 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Gabapentin Blood alkaline phosphatase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Blood bilirubin increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Blood creatine phosphokinase increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Blood potassium decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Blood potassium increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Blood pressure decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Bone pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Bradyphrenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Breast cancer 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Breast enlargement 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Bronchitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Burning sensation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Bursitis 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin C-reactive protein increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Candida infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Cardiac disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Cardiac failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Cardiac failure acute 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Cardiac failure congestive 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Cardiac murmur 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Cardiomyopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Carpal tunnel syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Catatonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Cerebrovascular accident 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Chest discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Chills 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Choking 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Cholecystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Chronic kidney disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Chronic obstructive pulmonary disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Circulatory collapse 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Coagulopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Cognitive disorder 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Gabapentin Colitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Confusional state 0.0 1.0 1.0 1.0 0.0 1.0 0.0 Gabapentin Coordination abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Cough 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Crying 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Gabapentin Cyanosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Cyst 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Cystitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Deafness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Deep vein thrombosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Delusion 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Dental caries 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Depressed level of consciousness 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Depressed mood 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Depression 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Gabapentin Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Diarrhoea 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Gabapentin Diplopia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Disease progression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Disease recurrence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Disorientation 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Disturbance in attention 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Drug dependence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Drug eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Drug hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Drug interaction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Drug withdrawal syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Drug-induced liver injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Dry eye 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Dry mouth 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Dry throat 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Dysarthria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Dysgeusia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Dyskinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Dysmenorrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Dysphagia 0.0 0.0 1.0 1.0 1.0 0.0 0.0 Gabapentin Dyspnoea 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Gabapentin Dysstasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Dystonia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Ear infection 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Gabapentin Ear pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Eczema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Electrocardiogram QT prolonged 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Emotional disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Emotional distress 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Encephalopathy 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Epilepsy 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Gabapentin Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Euphoric mood 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Extrapyramidal disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Eye disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Eye pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Eye pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Eye swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Facial paralysis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Gabapentin Fear 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Feeding disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Gabapentin Feeling cold 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Fluid overload 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Fluid retention 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Gabapentin Flushing 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Foetal growth restriction 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Gabapentin Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Frequent bowel movements 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Gallbladder disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Gastric haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Gastrointestinal haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Gastrointestinal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Gastrooesophageal reflux disease 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Gabapentin Generalised tonic-clonic seizure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Gingivitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Gout 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Gynaecomastia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Haematemesis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Gabapentin Haemoglobin decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Haemoptysis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Haemorrhage 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Hallucination 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Hallucination, visual 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Heart rate decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Heart rate increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Heart rate irregular 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Hepatic cirrhosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Hepatic steatosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Hepatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Hepatocellular injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Hepatotoxicity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Hernia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Herpes zoster 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Hip fracture 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Hyperbilirubinaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Hyperhidrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Hyperkalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Hyperpyrexia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Hypersomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Hyperthermia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Hyperventilation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Hypoacusis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Gabapentin Hypoaesthesia oral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Hypoglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Hypokalaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Hypokinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Hyponatraemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Hypothermia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Hypothyroidism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Hypotonia 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Gabapentin Hypoxia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Ileus paralytic 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Inappropriate antidiuretic hormone secretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Increased appetite 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Influenza like illness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Insomnia 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Gabapentin Intentional self-injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Intervertebral disc protrusion 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Irritability 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Ischaemic stroke 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Joint stiffness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Joint swelling 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Lactic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Leukocytosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Leukopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Libido decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Limb discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Liver function test abnormal 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Gabapentin Localised infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Loss of consciousness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Lower respiratory tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Lung disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Lung neoplasm malignant 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Lymphadenopathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Malignant neoplasm progression 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Mania 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Melaena 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Menorrhagia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Mental disorder 0.0 1.0 1.0 0.0 1.0 0.0 0.0 Gabapentin Mental impairment 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Gabapentin Mental status changes 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Metabolic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Metabolic disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Micturition urgency 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Middle insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Migraine 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Gabapentin Miosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Mobility decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Mood altered 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Gabapentin Mood swings 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Motor dysfunction 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Gabapentin Mouth ulceration 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Movement disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Mucosal inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Muscle atrophy 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Gabapentin Muscle contractions involuntary 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Muscle rigidity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Muscle tightness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Gabapentin Muscle twitching 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Musculoskeletal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Musculoskeletal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Musculoskeletal stiffness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Gabapentin Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Mydriasis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Myocardial ischaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Myoclonus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Nasal dryness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Nasopharyngitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Nausea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Neck pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Nephrolithiasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Nervousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Neuralgia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Neuroleptic malignant syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Gabapentin Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Night sweats 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Nightmare 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Gabapentin Nocturia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Oedema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Oral discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Oral pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Oropharyngeal pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Orthostatic hypotension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Osteoarthritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Osteoporosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Oxygen saturation decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Gabapentin Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Pallor 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Palpitations 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Pancytopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Panic attack 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Paralysis 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Paranoia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Parkinson's disease 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Peripheral coldness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Peripheral sensory neuropathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Gabapentin Personality change 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Personality disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Pharyngeal oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Phlebitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Photophobia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Photosensitivity reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Platelet count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Pleural effusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Pollakiuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Polyneuropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Poor quality sleep 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Gabapentin Prothrombin time prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Psychotic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Pulmonary congestion 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Pulmonary embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Rash 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Rash macular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Rash pruritic 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Rectal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Renal impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Renal tubular necrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Respiratory depression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Respiratory disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Respiratory distress 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Gabapentin Respiratory failure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Restless legs syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Restlessness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Rheumatoid arthritis 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Rhinorrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Scab 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Sedation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Seizure 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Gabapentin Sensory disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Sensory loss 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Sepsis 1.0 1.0 0.0 0.0 1.0 0.0 0.0 Gabapentin Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Serotonin syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Sexual dysfunction 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Sinus tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Sinusitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Skin burning sensation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Skin cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Skin discolouration 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Skin disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Skin exfoliation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Skin lesion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Skin ulcer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Sleep apnoea syndrome 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Sleep disorder 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Gabapentin Sluggishness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Somnolence 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Sopor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Speech disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Status epilepticus 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Stomatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Stress 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Stupor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Subdural haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Suicidal ideation 0.0 1.0 0.0 1.0 0.0 1.0 1.0 Gabapentin Suicide attempt 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Gabapentin Swelling 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Swelling face 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Swollen tongue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Tachypnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Tardive dyskinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Tendon rupture 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Thinking abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Thirst 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Throat tightness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Tooth disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Toxic epidermal necrolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Toxic skin eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Transient ischaemic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Tremor 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Gabapentin Troponin increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Unresponsive to stimuli 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Urinary incontinence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Urinary tract infection 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Gabapentin Urine abnormality 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Vaginal haemorrhage 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Ventricular arrhythmia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gabapentin Vertigo 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Vision blurred 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Visual acuity reduced 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Visual field defect 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Visual impairment 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Vomiting 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Gabapentin Weight decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gabapentin Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Gabapentin Wheezing 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gabapentin Withdrawal syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gabapentin enacarbil Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin enacarbil Coma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin enacarbil Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin enacarbil Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin enacarbil Depressed level of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin enacarbil Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gabapentin enacarbil Dyskinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gabapentin enacarbil Respiratory depression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gadobenate dimeglumine Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gadobenate dimeglumine Anaphylactic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gadobenate dimeglumine Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gadobenate dimeglumine Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Gadobenate dimeglumine Asthenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gadobenate dimeglumine Burning sensation 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Gadobenate dimeglumine Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gadobenate dimeglumine Confusional state 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gadobenate dimeglumine Cyanosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gadobenate dimeglumine Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gadobenate dimeglumine Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gadobenate dimeglumine Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gadobenate dimeglumine Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadobenate dimeglumine Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadobenate dimeglumine Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gadobenate dimeglumine Hypoaesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gadobenate dimeglumine Inflammation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gadobenate dimeglumine Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gadobenate dimeglumine Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gadobenate dimeglumine Muscle spasms 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gadobenate dimeglumine Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadobenate dimeglumine Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gadobenate dimeglumine Pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Gadobenate dimeglumine Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadobenate dimeglumine Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Gadobenate dimeglumine Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadobenate dimeglumine Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gadobenate dimeglumine Tinnitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gadobenate dimeglumine Tremor 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gadobenate dimeglumine Urine analysis abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gadobenate dimeglumine Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gadobenate dimeglumine Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadobenate dimeglumine Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gadobutrol Abdominal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadobutrol Anaphylactic shock 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Gadobutrol Burning sensation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gadobutrol Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gadobutrol Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gadobutrol Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gadobutrol Cyanosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gadobutrol Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gadobutrol Dysgeusia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gadobutrol Dyspnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Gadobutrol Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gadobutrol Feeling hot 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gadobutrol Flushing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gadobutrol Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gadobutrol Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gadobutrol Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gadobutrol Hypoaesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gadobutrol Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Gadobutrol Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadobutrol Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gadobutrol Malaise 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gadobutrol Nausea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gadobutrol Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadobutrol Pallor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gadobutrol Palpitations 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadobutrol Paraesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gadobutrol Pruritus 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Gadobutrol Rash 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gadobutrol Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gadobutrol Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gadobutrol Sneezing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gadobutrol Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Gadobutrol Urticaria 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Gadobutrol Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadobutrol Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gadodiamide Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadodiamide Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gadodiamide Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadodiamide Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadodiamide Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadodiamide Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadodiamide Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadodiamide Rash 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadodiamide Skin disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadodiamide Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadolinium Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadolinium Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadolinium Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadolinium Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadolinium Burning sensation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadolinium Confusional state 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadolinium Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadolinium Dysphagia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadolinium Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gadolinium Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadolinium Feeling abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gadolinium Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadolinium Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadolinium Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gadolinium Inflammation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadolinium Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadolinium Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadolinium Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadolinium Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadolinium Nausea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gadolinium Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadolinium Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadolinium Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadolinium Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadolinium Rash 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadolinium Seizure 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadolinium Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadolinium Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadolinium Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadolinium Vomiting 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadoteridol Anaphylactic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gadoteridol Cardiac arrest 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gadoteridol Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadoteridol Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gadoteridol Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadoteridol Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gadoteridol Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadoteridol Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadoteridol Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gadoteridol Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadoteridol Urticaria 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Gadoversetamide Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gadoversetamide Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadoversetamide Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gadoversetamide Pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Galantamine Abdominal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Galantamine Aphasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Galantamine Asthenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Galantamine Blood creatine phosphokinase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Galantamine Bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Galantamine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Galantamine Decreased appetite 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Galantamine Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Galantamine Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Galantamine Dyspnoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Galantamine Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Galantamine Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Galantamine Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Galantamine Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Galantamine Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Galantamine Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Galantamine Mania 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Galantamine Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Galantamine Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Galantamine Renal failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Galantamine Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Galantamine Sinus bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Galantamine Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Galantamine Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Galantamine Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Galantamine hydrobromide Renal failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ganciclovir Acute kidney injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ganciclovir Agranulocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ganciclovir Anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ganciclovir Bone marrow failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ganciclovir Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ganciclovir Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ganciclovir Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ganciclovir Hyperkalaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ganciclovir Hypotension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ganciclovir Leukopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ganciclovir Liver function test abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ganciclovir Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ganciclovir Nephropathy toxic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ganciclovir Neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ganciclovir Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ganciclovir Pneumocystis jirovecii pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ganciclovir Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ganciclovir Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ganciclovir Renal impairment 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ganciclovir Seizure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ganciclovir Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ganciclovir Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ganciclovir Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ganirelix acetate Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gefitinib Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gefitinib Acute respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Asthenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gefitinib Cerebral infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Coma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gefitinib Constipation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Decreased appetite 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Deep vein thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gefitinib Dehydration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Diarrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Disease progression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gefitinib Drug interaction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Drug resistance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gefitinib Dry eye 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gefitinib Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gefitinib Dry skin 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Duodenal ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gefitinib Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gefitinib Dysphagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Dyspnoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Fatigue 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Febrile neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gefitinib Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gefitinib Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Headache 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Hepatic function abnormal 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gefitinib Hypophagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Hypoxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gefitinib Infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Gefitinib Interstitial lung disease 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Lung disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Malaise 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Gefitinib Metastases to central nervous system 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Gefitinib Metastases to liver 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Gefitinib Metastases to lung 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Gefitinib Mouth ulceration 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gefitinib Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Nail disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gefitinib Nausea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Neoplasm progression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gefitinib Oxygen saturation decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gefitinib Pericardial effusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Peritonitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Pleural effusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gefitinib Pulmonary embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Pyrexia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Rash 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Stomatitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Treatment failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gefitinib Vomiting 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gefitinib Weight decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Acute hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Acute myeloid leukaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Agranulocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gemcitabine Anaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Arrhythmia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Ascites 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Asthenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Atelectasis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Blister 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Blood bilirubin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Bone marrow failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine C-reactive protein increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Candida infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Clostridium difficile colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Colitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Confusional state 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Congestive cardiomyopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Cough 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Deep vein thrombosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gemcitabine Dehydration 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Gemcitabine Disease recurrence 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Gemcitabine Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Drug intolerance 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Drug resistance 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Gemcitabine Dyspnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Dyspnoea exertional 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Ejection fraction decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Encephalopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Epistaxis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Febrile neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Flank pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Gastric haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Generalised oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Haematemesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Haematochezia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Haematuria 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Haemolytic anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Haemoptysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Hepatotoxicity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Hypoalbuminaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Ischaemic stroke 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Jaundice 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Leukopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gemcitabine Lung disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Lung infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Gemcitabine Metastases to liver 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gemcitabine Metastases to lung 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Musculoskeletal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Myositis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Necrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Neuralgia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gemcitabine Neurotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gemcitabine Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Gemcitabine Neutrophil count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Oxygen saturation decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Pallor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Pancreatic carcinoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Pancytopenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Pericardial effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Pleural effusion 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Pneumonitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Pollakiuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Polyneuropathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Proteinuria 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Pulmonary embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Pulmonary fibrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Renal tubular necrosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Sepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Septic shock 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Stress cardiomyopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Syncope 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Transaminases increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gemcitabine Treatment failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Tumour lysis syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Urosepsis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Agranulocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Alanine aminotransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Anaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Aspartate aminotransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Asthenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Blood alkaline phosphatase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Blood bilirubin increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Blood creatinine increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Cardiac failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Cardiac failure congestive 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Cardiotoxicity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Cellulitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Cough 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Decreased appetite 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Diarrhoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Drug interaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Dyspnoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Erythema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Febrile neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Gastrointestinal disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Generalised oedema 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Haematuria 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Hepatotoxicity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Hyperbilirubinaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Hypertension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Hypotension 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Hypoxia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Insomnia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Interstitial lung disease 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Liver function test increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Lung infiltration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Malaise 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gemcitabine hydrochloride Neurotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gemcitabine hydrochloride Neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Pancytopenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Pleural effusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Posterior reversible encephalopathy syndrome 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Proteinuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Pulmonary fibrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Renal impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Thrombocytosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Gemcitabine hydrochloride Toxic epidermal necrolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Vasculitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gemcitabine hydrochloride Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Gemfibrozil Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemfibrozil Acute kidney injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gemfibrozil Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gemfibrozil Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Gentamicin Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Gentamicin Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gentamicin Anuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gentamicin Balance disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gentamicin Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gentamicin Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gentamicin Candida infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gentamicin Deafness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gentamicin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gentamicin Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gentamicin Dehydration 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Gentamicin Diarrhoea 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Gentamicin Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gentamicin Drug reaction with eosinophilia and systemic symptoms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gentamicin Dysphagia 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Gentamicin Dyspnoea 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Gentamicin Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gentamicin Malaise 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Gentamicin Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gentamicin Muscular weakness 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Gentamicin Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gentamicin Pneumonia 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Gentamicin Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gentamicin Pyrexia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Gentamicin Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gentamicin Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gentamicin Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gentamicin Renal impairment 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gentamicin Renal tubular necrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gentamicin Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gentamicin Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gentamicin Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gentamicin Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gentamicin Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Gentamicin Vomiting 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Gilteritinib Acute kidney injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gilteritinib Acute myeloid leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gilteritinib Anaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gilteritinib Blood lactate dehydrogenase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gilteritinib Bone marrow failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gilteritinib Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gilteritinib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gilteritinib Diarrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gilteritinib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gilteritinib Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gilteritinib Electrocardiogram QT prolonged 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gilteritinib Febrile neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gilteritinib Gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gilteritinib Hepatic function abnormal 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gilteritinib Herpes zoster 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gilteritinib Hypokalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Gilteritinib Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gilteritinib Liver disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gilteritinib Lung disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Gilteritinib Malaise 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gilteritinib Melaena 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gilteritinib Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gilteritinib Neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gilteritinib Neutrophil count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gilteritinib Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gilteritinib Platelet count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gilteritinib Pleural effusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gilteritinib Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gilteritinib Pyrexia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gilteritinib Rash 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Gilteritinib Renal impairment 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gilteritinib Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gilteritinib Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gilteritinib Tumour lysis syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Gilteritinib White blood cell count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Glatiramer Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glatiramer Cerebrovascular accident 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glatiramer Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glatiramer Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Glatiramer Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glatiramer Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glatiramer Injection site pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer Injection site reaction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glatiramer Muscle spasms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glatiramer Myocardial infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glatiramer Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glatiramer Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glatiramer Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glatiramer Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glatiramer Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glatiramer acetate Abdominal distension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Glatiramer acetate Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Arthralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Asthenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glatiramer acetate Back pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Glatiramer acetate Blindness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Cardiac disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glatiramer acetate Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glatiramer acetate Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Cerebrovascular accident 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glatiramer acetate Chest pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Chills 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glatiramer acetate Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Cystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glatiramer acetate Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Depressed level of consciousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Diarrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Diplopia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Dysgeusia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Dysphonia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Dyspnoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Dysuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Ear pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Erythema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Eye disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Facial paralysis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Feeling abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Flushing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Glatiramer acetate Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Hyperhidrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Hypoaesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glatiramer acetate Ill-defined disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glatiramer acetate Injection site pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Injection site reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Liver injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Loss of consciousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Malaise 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Memory impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Micturition urgency 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Migraine 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Muscle spasms 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Muscle twitching 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Muscular weakness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Musculoskeletal stiffness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Neck pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glatiramer acetate Nervousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Optic neuritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Paraesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Pericardial effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glatiramer acetate Photophobia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glatiramer acetate Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Pulmonary embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Glatiramer acetate Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glatiramer acetate Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Renal failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Glatiramer acetate Rheumatoid arthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Sepsis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glatiramer acetate Shock 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Sinusitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Skin disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Skin exfoliation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Skin necrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Somnolence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Speech disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Syncope 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Systemic lupus erythematosus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Tachycardia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Thinking abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glatiramer acetate Tinnitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Tremor 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Urinary incontinence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Glatiramer acetate Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glatiramer acetate Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Vertigo 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Vomiting 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Weight decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glatiramer acetate Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Gliclazide Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Altered state of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Anuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Aphasia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Blood creatine phosphokinase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Blood creatinine increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Blood glucose decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Glimepiride Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Glimepiride C-reactive protein increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Glimepiride Cerebrovascular accident 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glimepiride Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Circulatory collapse 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Coma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Glimepiride Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Glimepiride Cyanosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Glimepiride Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Diarrhoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Disturbance in attention 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Glimepiride Drug abuse 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Glimepiride Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Glimepiride Gait disturbance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glimepiride Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Hyperkalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Glimepiride Hypoglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Incontinence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Glimepiride Interstitial lung disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Lactic acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Glimepiride Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Glimepiride Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glimepiride Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Glimepiride Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Paresis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Glimepiride Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Rash pruritic 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Glimepiride Renal failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Glimepiride Renal impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Glimepiride Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Sopor 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Unresponsive to stimuli 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Glimepiride Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Glimepiride Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glipizide Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glipizide Blood glucose increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glipizide Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Glipizide Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Glipizide Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Glipizide Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glipizide Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Glipizide Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glipizide Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glipizide Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glipizide Encephalopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glipizide Hypoglycaemia 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Glipizide Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glipizide Hypothermia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glipizide Hypotonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glipizide Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glipizide Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Glipizide Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Glipizide Unresponsive to stimuli 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glucagon Hypoglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Glucagon Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glutamine Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glutamine Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glutamine Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glutamine Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glutamine Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glutamine Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glutamine Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glutamine Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glutamine Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glutamine Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glutamine Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glutamine Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glyburide Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glyburide Brain oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Glyburide Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Glyburide Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glyburide Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glyburide Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glyburide Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glyburide Hypoglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Glyburide Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glyburide Lactic acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glyburide Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glyburide Unresponsive to stimuli 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycerol phenylbutyrate Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycerol phenylbutyrate Aggression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycerol phenylbutyrate Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycerol phenylbutyrate Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycerol phenylbutyrate Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycerol phenylbutyrate Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycerol phenylbutyrate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Glycerol phenylbutyrate Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycerol phenylbutyrate Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycerol phenylbutyrate Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycerol phenylbutyrate Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycerol phenylbutyrate Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycerol phenylbutyrate Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycerol phenylbutyrate Gastroenteritis viral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycerol phenylbutyrate Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycerol phenylbutyrate Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycerol phenylbutyrate Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycerol phenylbutyrate Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycerol phenylbutyrate Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycerol phenylbutyrate Irritability 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycerol phenylbutyrate Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycerol phenylbutyrate Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycerol phenylbutyrate Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycerol phenylbutyrate Metabolic acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycerol phenylbutyrate Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycerol phenylbutyrate Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycerol phenylbutyrate Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycerol phenylbutyrate Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycerol phenylbutyrate Respiratory failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycerol phenylbutyrate Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycerol phenylbutyrate Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycerol phenylbutyrate Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycerol phenylbutyrate Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycerol phenylbutyrate Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycopyrrolate Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycopyrrolate Anaphylactic reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glycopyrrolate Asthenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Glycopyrrolate Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Glycopyrrolate Cardiac disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Glycopyrrolate Electrocardiogram QT prolonged 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycopyrrolate Epistaxis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Glycopyrrolate Erythema 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Glycopyrrolate Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Glycopyrrolate Feeling abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Glycopyrrolate Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Glycopyrrolate Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Glycopyrrolate Hypersensitivity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Glycopyrrolate Hypoaesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Glycopyrrolate Nasal congestion 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Glycopyrrolate Nasopharyngitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Glycopyrrolate Nervousness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Glycopyrrolate Pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Glycopyrrolate Pain in extremity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Glycopyrrolate Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glycopyrrolate Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycopyrrolate Productive cough 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Glycopyrrolate Pruritus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Glycopyrrolate Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Glycopyrrolate Rhinitis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Glycopyrrolate Seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glycopyrrolate Sinus congestion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glycopyrrolate Sinusitis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Glycopyrrolate Throat irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glycopyrrolate Upper respiratory tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glycopyrrolate Urinary retention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glycopyrrolate Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Glycopyrronium Chronic obstructive pulmonary disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Glycopyrronium Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Goserelin Anaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Goserelin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Goserelin Malignant neoplasm progression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Goserelin acetate Abdominal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Goserelin acetate Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Goserelin acetate Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Goserelin acetate Asthenia 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Goserelin acetate Back pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Goserelin acetate Bone pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Goserelin acetate Cardiac failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Goserelin acetate Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Goserelin acetate Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Goserelin acetate Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Goserelin acetate Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Goserelin acetate Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Goserelin acetate Hot flush 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Goserelin acetate Hyperhidrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Goserelin acetate Hypertension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Goserelin acetate Lethargy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Goserelin acetate Oedema peripheral 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Goserelin acetate Pain 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Goserelin acetate Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Goserelin acetate Pulmonary embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Goserelin acetate Somnolence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Goserelin acetate Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Goserelin acetate Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Granisetron Aspartate aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Granisetron Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Granisetron Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Granisetron Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Granisetron Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Granisetron Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Granisetron Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Granisetron Serotonin syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Granisetron Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Granisetron Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Griseofulvin Drug reaction with eosinophilia and systemic symptoms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Guaifenesin Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Guaifenesin Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Guaifenesin Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Guanfacine Aggression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Guanfacine Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Guanfacine Disturbance in attention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Guanfacine Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Guanfacine Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Guanfacine Irritability 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Guanfacine Psychomotor hyperactivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Guanfacine Sinus bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Guanfacine Suicidal ideation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Guanfacine Suicide attempt 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Guanfacine Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Guanfacine hydrochloride Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Guanfacine hydrochloride Chest pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Guanfacine hydrochloride Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Guanfacine hydrochloride Malaise 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Guanfacine hydrochloride Somnolence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Haloperidol Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Aggression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Agitation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Agranulocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Altered state of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Anaphylactic reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Haloperidol Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Anxiety 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Arrhythmia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Ataxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Blood creatine phosphokinase increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Body temperature increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Catatonia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Chronic obstructive pulmonary disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Confusional state 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Death 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Delirium 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Depressed level of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Depression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Haloperidol Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Disturbance in attention 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Haloperidol Drug abuse 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Dry mouth 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Dyskinesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Haloperidol Dysphagia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Dyspnoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Haloperidol Dystonia 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Haloperidol Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Embolism venous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Haloperidol Extrapyramidal disorder 0.0 0.0 1.0 0.0 0.0 1.0 0.0 Haloperidol Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Haloperidol Gait disturbance 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Haloperidol Generalised tonic-clonic seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Hallucination, visual 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Hyperhidrosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Hyperreflexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Hypertonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Hypoglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Hypokalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Hypothermia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Insomnia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Haloperidol Intentional self-injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Haloperidol Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Leukocytosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Malnutrition 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Muscle rigidity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Muscle spasms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Musculoskeletal stiffness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Haloperidol Myalgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Myoclonus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Neuroleptic malignant syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Haloperidol Parkinsonism 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Haloperidol Pneumonia 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Haloperidol Pneumonia aspiration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Psychomotor hyperactivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Psychotic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Pulmonary embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Pyrexia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Renal failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Respiratory depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Haloperidol Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Salivary hypersecretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Sexual dysfunction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Sinus bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Sluggishness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Haloperidol Somnolence 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Sopor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Speech disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Haloperidol Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Swollen tongue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Haloperidol Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Tardive dyskinesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Haloperidol Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Haloperidol Torsade de pointes 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Tremor 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Haloperidol Urinary retention 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Ventricular arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Ventricular fibrillation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Haloperidol Visual impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Haloperidol Weight decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Haloperidol Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Haloperidol decanoate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Haloperidol decanoate Euphoric mood 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Haloperidol decanoate Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Haloperidol decanoate Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Haloperidol decanoate Neuroleptic malignant syndrome 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Haloperidol decanoate Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Haloperidol decanoate Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Haloperidol lactate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Haloperidol lactate Extrapyramidal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Haloperidol lactate Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Heparin sodium Anaphylactoid reaction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Heparin sodium Chills 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Heparin sodium Haematoma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Heparin sodium Haemorrhage 1.0 1.0 0.0 0.0 0.0 1.0 0.0 Heparin sodium Headache 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Heparin sodium Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Heparin sodium Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Heparin sodium Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Heparin sodium Skin necrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Heparin sodium Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Heparin sodium Thrombosis 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Heparin sodium Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydralazine hydrochloride Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydralazine hydrochloride Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydralazine hydrochloride Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydralazine hydrochloride Hepatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydralazine hydrochloride Hypoaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydralazine hydrochloride Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydralazine hydrochloride Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydralazine hydrochloride Paraesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydralazine hydrochloride Purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydralazine hydrochloride Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Acute generalised exanthematous pustulosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Acute respiratory distress syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Angina pectoris 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Angioedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Aphasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Ascites 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Asthenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Ataxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Atrioventricular block first degree 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrochlorothiazide Balance disorder 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Hydrochlorothiazide Basal cell carcinoma 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Hydrochlorothiazide Blood creatinine increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Blood potassium decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Blood pressure decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Blood pressure increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Blood urea increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide C-reactive protein increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Cerebrovascular accident 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrochlorothiazide Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Chest pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Chills 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Chronic kidney disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Confusional state 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Deafness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrochlorothiazide Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Delirium 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Dermatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Diarrhoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Disturbance in attention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Diverticulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Dizziness 0.0 0.0 1.0 1.0 0.0 1.0 0.0 Hydrochlorothiazide Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Dyspnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Eczema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Electrolyte imbalance 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Encephalopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Epistaxis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Gastrointestinal disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Gout 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Hepatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Hypercalcaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Hyperglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Hyperkalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Hypernatraemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Hypertension 0.0 0.0 1.0 0.0 0.0 1.0 0.0 Hydrochlorothiazide Hypertriglyceridaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrochlorothiazide Hypocalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Hypokalaemia 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Hydrochlorothiazide Hypomagnesaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Hyponatraemia 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Hydrochlorothiazide Hypophagia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Hypovolaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Hypoxia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Inappropriate antidiuretic hormone secretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Lactic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Leukocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Loss of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Memory impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Metabolic acidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Musculoskeletal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrochlorothiazide Nausea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Nocturia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Oedema peripheral 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Osteoporosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydrochlorothiazide Oxygen saturation decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Pain in extremity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Pallor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Pancreatitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrochlorothiazide Platelet count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Pollakiuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Polyuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Hydrochlorothiazide Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Pruritus 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Pulmonary oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Rash generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Renal failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Renal impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Renal tubular necrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Respiratory distress 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Restlessness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Seizure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Septic shock 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Sinus bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Sinus tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Skin cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydrochlorothiazide Skin lesion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Somnolence 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Squamous cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydrochlorothiazide Stevens-Johnson syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Suicide attempt 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Swelling face 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Tension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Torsade de pointes 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Toxic epidermal necrolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Unresponsive to stimuli 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Urinary tract disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Urinary tract infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Vascular purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Ventricular fibrillation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrochlorothiazide Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Weight increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrochlorothiazide Wheezing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrocodone Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydrocodone Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydrocortisone Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrocortisone Abdominal pain upper 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrocortisone Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Anaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrocortisone Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrocortisone Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrocortisone Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrocortisone Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Asthma 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Burning sensation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrocortisone Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrocortisone Chronic obstructive pulmonary disease 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrocortisone Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydrocortisone Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrocortisone Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Dermatitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Diarrhoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydrocortisone Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrocortisone Drug dependence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Drug hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrocortisone Drug withdrawal syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Dry skin 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrocortisone Eczema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Erythema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Feeling abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydrocortisone Herpes zoster 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrocortisone Hyperhidrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydrocortisone Hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrocortisone Hypokalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrocortisone Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrocortisone Increased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Inflammation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Leukocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrocortisone Loss of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrocortisone Malaise 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Myopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrocortisone Nausea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydrocortisone Oedema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Oesophagitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrocortisone Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydrocortisone Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Pyrexia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Rash 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrocortisone Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrocortisone Skin burning sensation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Skin disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Skin exfoliation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Skin hyperpigmentation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Skin infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrocortisone Swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrocortisone Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrocortisone Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydrocortisone Urinary tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydrocortisone Urticaria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Viral infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydrocortisone Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Visual acuity reduced 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydrocortisone Weight decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone acetate Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone butyrate Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydrocortisone sodium succinate Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydrocortisone sodium succinate Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydromorphone Abdominal pain 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydromorphone Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydromorphone Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydromorphone Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydromorphone Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydromorphone Blood pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydromorphone Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydromorphone Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydromorphone Cardiac disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydromorphone Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydromorphone Confusional state 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydromorphone Constipation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydromorphone Contusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydromorphone Death 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Hydromorphone Depression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydromorphone Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydromorphone Drug dependence 1.0 0.0 0.0 1.0 1.0 0.0 0.0 Hydromorphone Drug hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydromorphone Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydromorphone Drug withdrawal syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydromorphone Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydromorphone Emotional distress 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydromorphone Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydromorphone Gait disturbance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydromorphone Hyperaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydromorphone Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydromorphone Hypertensive crisis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydromorphone Hyponatraemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydromorphone Hypoxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydromorphone Injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydromorphone Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydromorphone Intracranial pressure increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydromorphone Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydromorphone Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydromorphone Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydromorphone Mental disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydromorphone Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydromorphone Miosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydromorphone Myalgia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydromorphone Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydromorphone Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydromorphone Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydromorphone Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydromorphone Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydromorphone Respiratory depression 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Hydromorphone Respiratory failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydromorphone Sedation 0.0 0.0 1.0 0.0 0.0 1.0 0.0 Hydromorphone Somnolence 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Hydromorphone Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydromorphone Unresponsive to stimuli 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Hydromorphone Vomiting 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydromorphone Weight decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydromorphone Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxychloroquine Abdominal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Hydroxychloroquine Abdominal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Abdominal pain upper 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxychloroquine Acute generalised exanthematous pustulosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxychloroquine Acute hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Acute kidney injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Agitation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Alanine aminotransferase increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Hydroxychloroquine Arrhythmia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Hydroxychloroquine Aspartate aminotransferase increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine Atrial fibrillation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Atrioventricular block complete 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine Blister 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine Blood creatine phosphokinase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Blood pressure increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Bone marrow failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxychloroquine Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxychloroquine Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Cardiac failure congestive 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Cardiomyopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Cardiotoxicity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxychloroquine Cerebral haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Cerebrovascular accident 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxychloroquine Chest discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Chest pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine Chills 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Confusional state 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine Contusion 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxychloroquine Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Diverticulitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxychloroquine Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine Drug eruption 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Hydroxychloroquine Drug hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Hydroxychloroquine Drug intolerance 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Hydroxychloroquine Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Drug-induced liver injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxychloroquine Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Dyspnoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine Ejection fraction decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Erythema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine Eye disorder 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Hydroxychloroquine Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine Gastrointestinal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine Hepatic encephalopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Hepatic enzyme increased 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Hydroxychloroquine Hepatic steatosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Hepatotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxychloroquine Herpes zoster 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Hydroxychloroquine Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Hypoxia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Ill-defined disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxychloroquine Inflammation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine Influenza like illness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxychloroquine Interstitial lung disease 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Joint swelling 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Hydroxychloroquine Left ventricular dysfunction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Lethargy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Liver disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxychloroquine Liver function test abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Loss of consciousness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine Lower respiratory tract infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine Lung disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxychloroquine Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Mental status changes 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Mouth ulceration 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxychloroquine Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Muscular weakness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Musculoskeletal stiffness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Hydroxychloroquine Myalgia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Myopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxychloroquine Neutropenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxychloroquine Oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxychloroquine Pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Hydroxychloroquine Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Hydroxychloroquine Palpitations 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Pancytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Posterior reversible encephalopathy syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 1.0 Hydroxychloroquine Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine Psoriasis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Rash 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine Rash erythematous 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Rash pruritic 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Rheumatoid arthritis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Hydroxychloroquine Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Sinus tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Sinusitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine Skin exfoliation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Skin ulcer 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Stevens-Johnson syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Stress 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxychloroquine Suicide attempt 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Swelling 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Hydroxychloroquine Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Systemic lupus erythematosus 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Hydroxychloroquine Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Tinnitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxychloroquine Torsade de pointes 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Toxic epidermal necrolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Treatment failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxychloroquine Unevaluable event 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxychloroquine Urinary tract infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxychloroquine Ventricular fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine Visual acuity reduced 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxychloroquine Visual field defect 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Hydroxychloroquine Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxychloroquine Weight decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine White blood cell count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxychloroquine sulfate Agranulocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxychloroquine sulfate Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Hydroxychloroquine sulfate Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Hydroxychloroquine sulfate Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine sulfate Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Hydroxychloroquine sulfate Headache 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Hydroxychloroquine sulfate Leukopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxychloroquine sulfate Nausea 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Hydroxychloroquine sulfate Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxychloroquine sulfate Purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxychloroquine sulfate Rash 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Hydroxychloroquine sulfate Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxychloroquine sulfate Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine sulfate Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxychloroquine sulfate Vertigo 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxychloroquine sulfate Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine sulfate Visual acuity reduced 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydroxychloroquine sulfate Visual field defect 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxychloroquine sulfate Vomiting 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Hydroxyprogesterone caproate Abdominal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxyprogesterone caproate Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxyprogesterone caproate Abortion spontaneous 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydroxyprogesterone caproate Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxyprogesterone caproate Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxyprogesterone caproate Asthma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxyprogesterone caproate Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxyprogesterone caproate Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxyprogesterone caproate Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxyprogesterone caproate Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxyprogesterone caproate Dyspepsia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxyprogesterone caproate Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxyprogesterone caproate Foetal death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydroxyprogesterone caproate Foetal growth restriction 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Hydroxyprogesterone caproate Haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxyprogesterone caproate Hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxyprogesterone caproate Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxyprogesterone caproate Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxyprogesterone caproate Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxyprogesterone caproate Insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxyprogesterone caproate Loss of consciousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxyprogesterone caproate Maternal drugs affecting foetus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydroxyprogesterone caproate Muscle spasms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxyprogesterone caproate Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxyprogesterone caproate Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxyprogesterone caproate Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxyprogesterone caproate Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxyprogesterone caproate Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxyprogesterone caproate Premature baby 0.0 0.0 1.0 0.0 1.0 0.0 1.0 Hydroxyprogesterone caproate Premature delivery 0.0 0.0 1.0 0.0 0.0 0.0 1.0 Hydroxyprogesterone caproate Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxyprogesterone caproate Syncope 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxyprogesterone caproate Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxyprogesterone caproate Vaginal discharge 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxyprogesterone caproate Vaginal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxyprogesterone caproate Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxyurea Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxyurea Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydroxyurea Acute myeloid leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydroxyurea Acute respiratory distress syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydroxyurea Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxyurea Back pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxyurea Blood creatinine increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxyurea Bone marrow failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxyurea Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxyurea Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydroxyurea Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxyurea Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydroxyurea Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxyurea Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxyurea Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydroxyurea Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydroxyurea Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxyurea Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxyurea Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydroxyurea Febrile neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxyurea Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxyurea Gastric cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxyurea Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydroxyurea Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxyurea Infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxyurea Lung neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxyurea Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydroxyurea Memory impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxyurea Mouth ulceration 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxyurea Myelodysplastic syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydroxyurea Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxyurea Night sweats 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxyurea Oropharyngeal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxyurea Pancytopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydroxyurea Premature baby 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxyurea Premature delivery 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Hydroxyurea Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydroxyurea Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hydroxyurea Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxyurea Skin ulcer 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hydroxyurea Stomatitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydroxyurea Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxyurea Tumour lysis syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxyurea Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxyurea Weight decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Hydroxyzine hydrochloride Respiratory depression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Hydroxyzine hydrochloride Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hydroxyzine hydrochloride Tremor 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Hyoscyamine Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hyoscyamine Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Hyoscyamine Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hyoscyamine Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Hyoscyamine sulfate Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibandronate sodium Abdominal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibandronate sodium Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibandronate sodium Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibandronate sodium Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibandronate sodium Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibandronate sodium Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibandronate sodium Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibandronate sodium Influenza 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibandronate sodium Influenza like illness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibandronate sodium Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibandronate sodium Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibandronate sodium Musculoskeletal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibandronate sodium Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibandronate sodium Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibandronate sodium Osteonecrosis of jaw 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Ibandronate sodium Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibandronic acid Abdominal pain upper 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibandronic acid Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibandronic acid Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibandronic acid Cardiac disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibandronic acid Dysphagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibandronic acid Femur fracture 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibandronic acid Hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibandronic acid Inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibandronic acid Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibandronic acid Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibandronic acid Osteoarthritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibandronic acid Osteonecrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibandronic acid Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibandronic acid Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibandronic acid Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibandronic acid Swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibandronic acid Vomiting 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibritumomab tiuxetan Anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibritumomab tiuxetan Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibritumomab tiuxetan Leukopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibritumomab tiuxetan Neutropenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibritumomab tiuxetan Thrombocytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Abasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Abdominal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Abdominal pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Abscess 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Acute coronary syndrome 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Acute myeloid leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Acute myocardial infarction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Acute pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Acute respiratory distress syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Acute respiratory failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Aggression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibrutinib Anaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Angina pectoris 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Aphasia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Appendicitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Arrhythmia supraventricular 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Arthralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibrutinib Arthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibrutinib Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Aspartate aminotransferase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Aspiration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Atelectasis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Atrial flutter 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Atrioventricular block complete 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Atrioventricular block second degree 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Bacteraemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Bacterial infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Balance disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Basal cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibrutinib Blindness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Ibrutinib Blister 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Blood alkaline phosphatase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Blood bilirubin increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Blood count abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Blood disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Blood glucose decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Blood lactate dehydrogenase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Blood potassium increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Blood pressure abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Blood pressure decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Blood uric acid increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Bone marrow failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Bone pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibrutinib Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Brain injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Burning sensation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib C-reactive protein increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Cachexia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Candida infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Cardiac disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Cardiac failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Cardiac failure acute 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Ibrutinib Cardiac failure congestive 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Cardiac tamponade 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Cardiogenic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Cardiomyopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Cardiotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibrutinib Cardiovascular disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibrutinib Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Cerebral haemorrhage 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Cerebral infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Cerebral ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Cerebrovascular accident 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Choking 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Cholecystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Chronic obstructive pulmonary disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Circulatory collapse 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Clostridium difficile colitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Clostridium difficile infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Coagulopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Cognitive disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Colitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Colon cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Coma 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Confusional state 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Congestive cardiomyopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Contusion 0.0 0.0 1.0 0.0 0.0 0.0 1.0 Ibrutinib Coronary artery disease 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Cystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibrutinib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Decubitus ulcer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Deep vein thrombosis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Delirium 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Dementia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Disseminated intravascular coagulation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Diverticulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Drug eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Drug intolerance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Drug resistance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Drug-induced liver injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Dry eye 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibrutinib Dry mouth 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Dry skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibrutinib Dysarthria 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Dysphagia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Dysphonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Dyspnoea exertional 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Eating disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Ecchymosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Ejection fraction decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Electrolyte imbalance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Encephalitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Encephalopathy 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Epilepsy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Epistaxis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibrutinib Eructation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Erythema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Erythema multiforme 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Eye disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibrutinib Eye haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibrutinib Faeces discoloured 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Failure to thrive 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Febrile neutropenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Feeding disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Feeling abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Feeling hot 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Femur fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Flank pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Fluid overload 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Fluid retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Flushing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Folliculitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Fracture 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Furuncle 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Gastric disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Gastric haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Gastric ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Gastroenteritis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Gastroenteritis viral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Gastrointestinal haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Gastrooesophageal reflux disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Generalised oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibrutinib Gout 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Haematemesis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Haematocrit decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Haemolytic anaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Haemoptysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibrutinib Haemorrhage intracranial 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Haemorrhagic stroke 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Ibrutinib Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Heart rate decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Heart rate irregular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Hemiparesis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ibrutinib Hepatic cirrhosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Hepatic enzyme increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Hernia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibrutinib Herpes simplex 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Herpes zoster 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Hip fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Hydronephrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Hypercalcaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Hyperglycaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Hyperkalaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Hyperpyrexia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Hypersensitivity vasculitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibrutinib Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Hypertensive crisis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Hyperuricaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Hypoacusis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibrutinib Hypoaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Hypocalcaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Hyponatraemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Hypotension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Hypoxia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Ileus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Ill-defined disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Immune system disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Inappropriate antidiuretic hormone secretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Interstitial lung disease 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Intestinal perforation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Ischaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibrutinib Ischaemic stroke 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Joint swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Laboratory test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Laceration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Lactic acidosis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Left ventricular dysfunction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Leukocytosis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Limb discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Liver function test abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Liver injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Local swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Localised infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Lower respiratory tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Lung disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Lung infection 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Lung infiltration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Lymphadenopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Lymphoedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Lymphoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Lymphopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Malignant melanoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibrutinib Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Malnutrition 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Melaena 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Meningitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Mental disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Mental status changes 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Metabolic acidosis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Metastases to liver 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Micturition urgency 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Mitral valve incompetence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Mobility decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Mucosal inflammation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Muscle spasms 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibrutinib Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Musculoskeletal chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Musculoskeletal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibrutinib Myelodysplastic syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Myocardial infarction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Myocardial ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Nail disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibrutinib Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Neck pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Neoplasm 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Neutrophil count decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Night sweats 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Oesophageal ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Oesophagitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Oral candidiasis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Osteomyelitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Osteoporosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibrutinib Oxygen saturation decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Pancreatic carcinoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Pancytopenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Paralysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Pericardial effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Pericarditis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Platelet count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Pleural effusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Pleurisy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Pneumocystis jirovecii pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Pneumonia aspiration 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Pneumonia bacterial 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Pneumonitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Pneumothorax 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Posterior reversible encephalopathy syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Proctalgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Productive cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Psoriasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibrutinib Pulmonary congestion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Pulmonary embolism 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Pulmonary haemorrhage 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Pulmonary hypertension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Pulmonary oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Purpura 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibrutinib Pyelonephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Pyrexia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Rash erythematous 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Rash generalised 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Rash maculo-papular 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Rash papular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibrutinib Rash pruritic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Red blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Renal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Renal failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Renal impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Renal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Respiratory disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Respiratory distress 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Respiratory failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Respiratory tract infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Restlessness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Retinal detachment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibrutinib Retinal haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibrutinib Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Sensory loss 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Sepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Sinus bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Sinus tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Sinusitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibrutinib Skin burning sensation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Skin cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibrutinib Skin discolouration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Skin infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Skin reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibrutinib Skin ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Small intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Speech disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Spinal fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Splenomegaly 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Staphylococcal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Stomatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Stress cardiomyopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Subarachnoid haemorrhage 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Subdural haematoma 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Supraventricular tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Swelling face 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Throat irritation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Tinnitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibrutinib Torsade de pointes 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Transaminases increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Transient ischaemic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Treatment failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibrutinib Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Troponin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Tumour lysis syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Unevaluable event 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Unresponsive to stimuli 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Upper gastrointestinal haemorrhage 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Upper limb fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Urinary incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Urosepsis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Urticaria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Ventricular arrhythmia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibrutinib Ventricular fibrillation 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Ventricular tachycardia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibrutinib Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib Weight increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib White blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibrutinib White blood cell count increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Abdominal distension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibuprofen Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Acidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Acute coronary syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Acute hepatic failure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Acute kidney injury 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Ibuprofen Acute myocardial infarction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Aggression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Agitation 0.0 1.0 1.0 0.0 1.0 0.0 0.0 Ibuprofen Agranulocytosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Alopecia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ibuprofen Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Ibuprofen Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Anaphylactoid reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Angioedema 0.0 1.0 0.0 0.0 0.0 1.0 1.0 Ibuprofen Anuria 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Anxiety 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Ibuprofen Aplastic anaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Apnoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Appendicitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Arrhythmia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Arthralgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ibuprofen Arthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibuprofen Aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Asthenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Asthma 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Ibuprofen Ataxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Atelectasis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Azotaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Bacteraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Blood bilirubin increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Blood creatinine increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Blood disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Blood lactate dehydrogenase increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Blood pressure increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Blood urea increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Brain injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Bronchitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Cardiac failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Cardiomyopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Cerebral haemorrhage 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Ibuprofen Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Chills 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ibuprofen Choking 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibuprofen Cholestasis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Chromaturia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Circulatory collapse 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Coagulopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Cognitive disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ibuprofen Colitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Confusional state 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Conjunctivitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Constipation 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Ibuprofen Contusion 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ibuprofen Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Deafness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibuprofen Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Decreased appetite 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Depressed level of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Depression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Dermatitis bullous 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Diarrhoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Diplopia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibuprofen Discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibuprofen Disorientation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Dizziness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Drug eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Drug hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Ibuprofen Drug intolerance 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Ibuprofen Drug-induced liver injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Dry eye 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibuprofen Duodenal ulcer 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Dysarthria 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Ibuprofen Dysphagia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Ecchymosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Encephalitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Encephalopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Epistaxis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Erectile dysfunction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Erythema multiforme 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Eye pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Eye swelling 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Eyelid oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibuprofen Fatigue 0.0 1.0 1.0 1.0 1.0 0.0 0.0 Ibuprofen Feeling abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Gastric ulcer 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Gastrointestinal haemorrhage 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Gastrointestinal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Haematemesis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Haematochezia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Haematocrit decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Haemoglobin decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Haemolytic anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Haemorrhage intracranial 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Ibuprofen Hallucination 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibuprofen Headache 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Ibuprofen Hepatic enzyme increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Hepatic function abnormal 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Ibuprofen Hepatitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Hepatocellular injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Hyperbilirubinaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Hyperhidrosis 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Ibuprofen Hyperkinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Ibuprofen Hypertension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Hypertensive crisis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibuprofen Hypertonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Hypoacusis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ibuprofen Hypoalbuminaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Hypocalcaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Hypoglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Hypothermia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Ibuprofen Hypotonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Hypoxia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Ill-defined disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Inflammation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ibuprofen Influenza 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibuprofen Injection site reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibuprofen Insomnia 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Ibuprofen Intestinal perforation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Jaundice 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Lacrimation increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Lactic acidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Lethargy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Leukopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Lip swelling 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Liver disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Liver function test abnormal 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Liver injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Loss of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Lymphadenopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Malaise 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ibuprofen Melaena 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Mental disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Mental status changes 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Metabolic acidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Mood swings 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Mouth ulceration 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Muscle spasms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Musculoskeletal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibuprofen Musculoskeletal stiffness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Myalgia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Myocardial infarction 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Ibuprofen Nasal congestion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibuprofen Nausea 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Ibuprofen Neuralgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ibuprofen Neuropathy peripheral 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Neutropenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Oedema 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Oedema peripheral 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Oesophagitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Oliguria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Optic neuritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibuprofen Pain 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Ibuprofen Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibuprofen Pallor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Palpitations 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Ibuprofen Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Pancytopenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Paraesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ibuprofen Paraesthesia oral 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Peptic ulcer 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Pharyngitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Platelet count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Pleural effusion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Pneumonia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Pneumonia bacterial 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Polyuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Proteinuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Prothrombin time prolonged 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Ibuprofen Pruritus generalised 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Ibuprofen Pulmonary alveolar haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Pulmonary congestion 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Pulmonary haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Pulmonary hypertension 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Ibuprofen Purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Rash 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ibuprofen Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Rash pustular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Rectal haemorrhage 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Ibuprofen Renal failure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Renal impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Renal tubular necrosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Respiratory depression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Respiratory disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Respiratory distress 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Respiratory failure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Restlessness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Rhinitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibuprofen Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Sinus bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Sinus tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Sinusitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Skin discolouration 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibuprofen Skin exfoliation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ibuprofen Skin lesion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Somnolence 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Speech disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Stevens-Johnson syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Suicide attempt 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Swelling 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ibuprofen Swelling face 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ibuprofen Swollen tongue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibuprofen Syncope 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Systemic lupus erythematosus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibuprofen Tachycardia 0.0 1.0 1.0 0.0 1.0 0.0 0.0 Ibuprofen Throat irritation 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Ibuprofen Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Thrombocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Ibuprofen Tinnitus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ibuprofen Toxic epidermal necrolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Tremor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ibuprofen Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Ulcer 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Ibuprofen Upper gastrointestinal haemorrhage 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Urinary incontinence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Urinary tract infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Urticaria 0.0 1.0 0.0 0.0 0.0 1.0 1.0 Ibuprofen Vascular purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Vertigo 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Ibuprofen Viral infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibuprofen Visual acuity reduced 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ibuprofen Visual field defect 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ibuprofen Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibuprofen Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ibuprofen Weight decreased 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Ibuprofen Wheezing 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Ibuprofen White blood cell count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen lysine Abdominal distension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibuprofen lysine Anaemia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibuprofen lysine Blood creatinine increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibuprofen lysine Renal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ibuprofen lysine Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ibuprofen lysine Urine output decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Icatibant acetate Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Icatibant acetate Headache 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Icatibant acetate Hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Icosapent ethyl Abdominal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Icosapent ethyl Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Icosapent ethyl Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Icosapent ethyl Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Idarubicin Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idarubicin Febrile neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Idarubicin Pancytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Idarubicin Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Idarubicin hydrochloride Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Idarubicin hydrochloride Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Abasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Abdominal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Acute respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Aphthous ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Aspartate aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Bacteraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib C-reactive protein increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Cardiac disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Colitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Colitis ulcerative 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Confusional state 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Dementia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Idelalisib Dermatitis exfoliative 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Idelalisib Diarrhoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Idelalisib Drug reaction with eosinophilia and systemic symptoms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Drug-induced liver injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Dyspnoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Electrolyte imbalance 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Enteritis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Enterocolitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Febrile neutropenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Fungal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Haemoglobin decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Herpes zoster 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Hypercalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Hypertension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Hyponatraemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Hypotension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Hypoxia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Interstitial lung disease 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Ischaemic stroke 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Jaundice 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Leukopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Liver disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Localised infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Lower respiratory tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Lung disorder 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Lung infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Lymphoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Myocardial infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Pancytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Pneumocystis jirovecii pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Pneumonia bacterial 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Pneumonitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Pulmonary embolism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Rash macular 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Idelalisib Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Renal impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Respiratory tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Sinusitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Skin cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Idelalisib Stevens-Johnson syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Thrombocytopenia 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Idelalisib Transaminases increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Idelalisib Unevaluable event 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Idelalisib White blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ifosfamide Acute kidney injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ifosfamide Acute myeloid leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ifosfamide Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ifosfamide Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ifosfamide Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ifosfamide Bone marrow failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ifosfamide Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ifosfamide Confusional state 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ifosfamide Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ifosfamide Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ifosfamide Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ifosfamide Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ifosfamide Encephalopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ifosfamide Febrile neutropenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ifosfamide Hypophosphataemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ifosfamide Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ifosfamide Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ifosfamide Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ifosfamide Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Ifosfamide Mucosal inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ifosfamide Myelodysplastic syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ifosfamide Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ifosfamide Neutropenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ifosfamide Neutrophil count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ifosfamide Platelet count decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ifosfamide Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ifosfamide Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ifosfamide Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ifosfamide Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ifosfamide Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ifosfamide Treatment failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ifosfamide Tubulointerstitial nephritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ifosfamide Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ifosfamide White blood cell count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iloprost Abdominal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Abdominal distension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Abdominal pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Acute kidney injury 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Acute respiratory failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Iloprost Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iloprost Asphyxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iloprost Asthenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Asthma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Atrial fibrillation 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Iloprost Atrial flutter 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Bacteraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Balance disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Blister 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Blood potassium increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Blood pressure decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Brain injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iloprost Cardiac disorder 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Iloprost Cardiac failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Cardiac failure congestive 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iloprost Cardiomegaly 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Cardiopulmonary failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iloprost Cellulitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iloprost Cerebrovascular accident 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Chest discomfort 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Choking 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iloprost Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Chronic obstructive pulmonary disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Circulatory collapse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iloprost Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Coma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iloprost Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Contusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Cough 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Cyanosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iloprost Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iloprost Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iloprost Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Depression 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Diabetes mellitus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Diarrhoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iloprost Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Drug interaction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iloprost Drug intolerance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Dysgeusia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Dyspnoea exertional 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Iloprost Eating disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Epistaxis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Erythema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iloprost Fatigue 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Fluid overload 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Fluid retention 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Flushing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Gait disturbance 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Gastric disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Gastrointestinal haemorrhage 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Iloprost Generalised oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Glossodynia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Gout 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Haematochezia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Haemoptysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iloprost Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iloprost Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Heart rate decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Heart rate increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Hepatic cirrhosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iloprost Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iloprost Hip fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Hyperhidrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iloprost Hyperkalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Hypersomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Hypoaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Hypoxia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Inflammation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Influenza 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Interstitial lung disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iloprost Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Jaundice 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iloprost Joint swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Localised infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Loss of consciousness 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Iloprost Lung disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Lung infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iloprost Malaise 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Memory impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Migraine 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iloprost Muscle spasms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iloprost Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Myalgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Iloprost Nasopharyngitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Nausea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iloprost Oedema 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Iloprost Oedema peripheral 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Oral pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Oxygen saturation decreased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Iloprost Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Pain in extremity 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Pericardial effusion 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Iloprost Peripheral swelling 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Pleural effusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Productive cough 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iloprost Pulmonary embolism 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Pulmonary fibrosis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Pulmonary haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iloprost Pulmonary hypertension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Pulmonary oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Pyrexia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Rash 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iloprost Renal disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Renal failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Renal impairment 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iloprost Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iloprost Respiratory disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iloprost Respiratory distress 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Iloprost Respiratory tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iloprost Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iloprost Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iloprost Sinusitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Skin discolouration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Sleep apnoea syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iloprost Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Speech disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iloprost Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iloprost Swelling 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Syncope 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Tinnitus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Unevaluable event 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Upper respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Urine output decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Vomiting 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Weight decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Weight increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iloprost Wheezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Imatinib Acute kidney injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib Acute myeloid leukaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib Acute respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib Alanine aminotransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Imatinib Asthenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib Blister 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Imatinib Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib Cardiac disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Imatinib Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib Cerebral infarction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Imatinib Colon cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Imatinib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib Disease recurrence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib Diverticulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Imatinib Drug interaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib Drug resistance 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib Electrocardiogram QT prolonged 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib Embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib Erythema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib Eyelid oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib Face oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Imatinib Feeling abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib Haematemesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Imatinib Haematochezia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Imatinib Hepatic failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib Hyperbilirubinaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Imatinib Hypotension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib Ischaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib Jaundice 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib Joint swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Imatinib Liver disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib Lung disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib Lymphadenopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib Metastases to liver 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib Muscle spasms 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib Myelodysplastic syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib Neoplasm 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib Pain in extremity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib Pancytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib Periorbital oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib Premature baby 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib Prostate cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib Pulmonary hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib Skin exfoliation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib Splenomegaly 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib Treatment failure 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib Urinary retention 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib Weight increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib White blood cell count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib mesylate Abdominal distension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Abdominal pain 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Abdominal pain upper 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Acute kidney injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Acute respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Agranulocytosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Alanine aminotransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Alopecia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Amylase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib mesylate Anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Angina pectoris 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib mesylate Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Aspartate aminotransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Asthenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Atrial fibrillation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Imatinib mesylate Back pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Blood alkaline phosphatase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Blood bilirubin increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Blood creatine phosphokinase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib mesylate Blood creatinine increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Blood lactate dehydrogenase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Bone marrow failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Brain oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Cachexia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Imatinib mesylate Cardiac tamponade 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Imatinib mesylate Colitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Confusional state 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib mesylate Decreased appetite 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Imatinib mesylate Dehydration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Imatinib mesylate Diarrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Dysgeusia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Imatinib mesylate Dyspepsia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Dysphagia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Dyspnoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Dyspnoea exertional 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Ecchymosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib mesylate Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Imatinib mesylate Epistaxis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Eye irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib mesylate Eye pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Eyelid oedema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Imatinib mesylate Febrile neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Flushing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib mesylate Fungal infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Gastrointestinal disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Generalised oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Gynaecomastia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Imatinib mesylate Haematemesis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Haematuria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Haemoglobin decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Headache 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Hepatitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Hepatotoxicity 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Herpes zoster 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Imatinib mesylate Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Hyperkalaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Imatinib mesylate Hypocalcaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Hypokalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Hypophosphataemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib mesylate Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Ileus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Imatinib mesylate Increased appetite 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib mesylate Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Imatinib mesylate Insomnia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Interstitial lung disease 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Intestinal obstruction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Intracranial pressure increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Jaundice 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Joint swelling 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Imatinib mesylate Lacrimation increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Imatinib mesylate Lethargy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Leukopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Lower respiratory tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Lymphadenopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Malaise 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Melaena 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Mouth ulceration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Imatinib mesylate Muscular weakness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Musculoskeletal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib mesylate Musculoskeletal stiffness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Imatinib mesylate Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Nephropathy toxic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib mesylate Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Imatinib mesylate Neurotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib mesylate Neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Neutrophil count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Night sweats 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Oesophagitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib mesylate Optic neuritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib mesylate Osteonecrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib mesylate Pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Pain in extremity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Imatinib mesylate Pancytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Imatinib mesylate Pericardial effusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Periorbital oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib mesylate Platelet count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Pleural effusion 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Imatinib mesylate Pulmonary haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Purpura 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib mesylate Pyrexia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Imatinib mesylate Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imatinib mesylate Retinal haemorrhage 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Imatinib mesylate Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Skin exfoliation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Stomatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Tachycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Thrombocytosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Thrombosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Transaminases increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Imatinib mesylate Upper respiratory tract infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Imatinib mesylate Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Imatinib mesylate Vomiting 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Imatinib mesylate Weight decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate Weight increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imatinib mesylate White blood cell count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Imipramine Arrhythmia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Imipramine Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Imipramine Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Imipramine Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Imipramine Mydriasis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Imipramine Tachycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Imiquimod Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Imiquimod Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Imiquimod Diarrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imiquimod Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Imiquimod Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Imiquimod Haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imiquimod Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Imiquimod Influenza like illness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Imiquimod Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Imiquimod Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Imiquimod Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Imiquimod Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Imiquimod Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Imiquimod Scab 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Imiquimod Stevens-Johnson syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Imiquimod Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Imiquimod Toxic epidermal necrolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Imiquimod Weight decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Indacaterol Angina pectoris 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Indacaterol Cardiac disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Indacaterol Chest discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Indacaterol Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Indacaterol Chronic obstructive pulmonary disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Indacaterol Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Indacaterol Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Indacaterol Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Indacaterol Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Indacaterol Nasopharyngitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Indacaterol Oropharyngeal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Indacaterol Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Indacaterol Throat irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Indapamide Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Indapamide Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Indapamide Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Indapamide Asthenia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Indapamide Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Indapamide Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Indapamide Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Indapamide Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Indapamide Cardiac arrest 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Indapamide Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Indapamide Confusional state 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Indapamide Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Indapamide Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Indapamide Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Indapamide Diarrhoea 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Indapamide Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Indapamide Drug interaction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Indapamide Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Indapamide Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Indapamide Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Indapamide Feeling abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Indapamide Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Indapamide Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Indapamide Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Indapamide Hypercalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Indapamide Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Indapamide Hypomagnesaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Indapamide Hyponatraemia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Indapamide Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Indapamide Hypotonia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Indapamide Inappropriate antidiuretic hormone secretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Indapamide Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Indapamide Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Indapamide Malaise 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Indapamide Muscle spasms 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Indapamide Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Indapamide Nausea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Indapamide Oedema peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Indapamide Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Indapamide Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Indapamide Paraesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Indapamide Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Indapamide Pollakiuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Indapamide Polyuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Indapamide Purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Indapamide Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Indapamide Renal impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Indapamide Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Indapamide Seizure 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Indapamide Somnolence 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Indapamide Swollen tongue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Indapamide Syncope 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Indapamide Torsade de pointes 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Indapamide Urinary tract infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Indapamide Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Indapamide Vertigo 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Indapamide Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Indapamide Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Indomethacin Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Indomethacin Drug hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Indomethacin Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Indomethacin Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Indomethacin Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Indomethacin Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Indomethacin Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Indomethacin Pulmonary hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Indomethacin Renal failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ingenol mebutate Basal cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ingenol mebutate Blister 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ingenol mebutate Dyspnoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ingenol mebutate Erythema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ingenol mebutate Eye irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ingenol mebutate Eye pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ingenol mebutate Eye swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ingenol mebutate Eyelid oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ingenol mebutate Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ingenol mebutate Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ingenol mebutate Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ingenol mebutate Periorbital oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ingenol mebutate Squamous cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ingenol mebutate Swelling face 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Insulin aspart Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Insulin aspart Asthenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Insulin aspart Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin aspart Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin aspart Diabetic ketoacidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin aspart Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin aspart Dyspepsia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin aspart Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Insulin aspart Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Insulin aspart Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Insulin aspart Hypoglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Insulin aspart Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin aspart Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin aspart Nausea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Insulin aspart Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Insulin aspart Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin aspart Oedema peripheral 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Insulin aspart Palpitations 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Insulin aspart Pneumothorax 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin aspart Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin aspart Sinusitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Insulin aspart Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin aspart Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin aspart Urticaria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin aspart Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin aspart Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Insulin degludec Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin degludec Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin degludec Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Insulin degludec Weight increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Insulin detemir Abdominal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin detemir Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin detemir Cardiac disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Insulin detemir Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin detemir Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin detemir Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Insulin detemir Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin detemir Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin detemir Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin detemir Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Insulin detemir Eye disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Insulin detemir Eye haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Insulin detemir Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin detemir Hypoglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Insulin detemir Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin detemir Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin detemir Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Insulin detemir Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin detemir Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Insulin detemir Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin detemir Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin detemir Rheumatoid arthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Insulin detemir Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin detemir Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin detemir Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin detemir Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin detemir Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Insulin detemir Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin glargine Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin glargine Acute coronary syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin glargine Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Insulin glargine Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Insulin glargine Blindness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Insulin glargine Bronchitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Insulin glargine Cardiac failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin glargine Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Insulin glargine Cerebrovascular accident 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Insulin glargine Coma 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Insulin glargine Cough 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Insulin glargine Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Insulin glargine Diabetes mellitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Insulin glargine Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Insulin glargine Dysgeusia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Insulin glargine Eczema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin glargine Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Insulin glargine Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin glargine Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin glargine Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Insulin glargine Herpes zoster 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Insulin glargine Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Insulin glargine Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin glargine Hypoglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Insulin glargine Hypotension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin glargine Infection 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Insulin glargine Inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin glargine Influenza 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Insulin glargine Injection site pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Insulin glargine Injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin glargine Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Insulin glargine Malnutrition 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Insulin glargine Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Insulin glargine Neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Insulin glargine Nervous system disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Insulin glargine Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Insulin glargine Oedema peripheral 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Insulin glargine Pain 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Insulin glargine Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Insulin glargine Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Insulin glargine Rash 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Insulin glargine Swelling 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Insulin glargine Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin glargine Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Insulin glargine Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Insulin glargine Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Insulin glulisine Headache 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Insulin glulisine Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin glulisine Hypoglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Insulin glulisine Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin glulisine Influenza 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Insulin glulisine Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Insulin glulisine Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Insulin lispro Abdominal pain 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Insulin lispro Anaphylactic reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Insulin lispro Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin lispro Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin lispro Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Insulin lispro Diabetes mellitus 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Insulin lispro Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin lispro Dyspnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Insulin lispro Erythema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin lispro Headache 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Insulin lispro Hypersensitivity 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Insulin lispro Hypoglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Insulin lispro Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin lispro Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin lispro Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin lispro Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin lispro Loss of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Insulin lispro Musculoskeletal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin lispro Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin lispro Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Insulin lispro Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin lispro Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin lispro Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Insulin lispro Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin lispro Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin lispro Swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Insulin lispro Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Interferon alfa-2b Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Interferon alfa-2b Aspartate aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Interferon alfa-2b Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Interferon alfa-2b Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Interferon alfa-2b Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Interferon alfa-2b Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Interferon alfa-2b Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Interferon alfa-2b Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Interferon alfa-2b Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Interferon alfa-2b Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Interferon alfa-2b Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Interferon alfa-2b Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Interferon alfa-2b Hyperglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Interferon alfa-2b Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Interferon alfa-2b Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Interferon alfa-2b Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Interferon alfa-2b Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Interferon alfa-2b Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Interferon alfa-2b Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Interferon alfa-2b Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Interferon alfa-2b Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Interferon alfa-2b Suicidal ideation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Interferon alfa-2b Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Interferon alfa-2b Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Interferon alfa-2b Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iodixanol Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iodixanol Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Iodixanol Anaphylactic reaction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Iodixanol Anaphylactic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Iodixanol Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iodixanol Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iodixanol Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Iodixanol Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Iodixanol Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iodixanol Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iodixanol Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iodixanol Face oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iodixanol Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iodixanol Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iodixanol Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iodixanol Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iodixanol Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iodixanol Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iodixanol Rash erythematous 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iodixanol Renal failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iodixanol Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Iodixanol Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iohexol Anaphylactic shock 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Iohexol Anaphylactoid reaction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iohexol Angioedema 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Iohexol Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iohexol Asthenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iohexol Bradycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Iohexol Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iohexol Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Iohexol Chills 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iohexol Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iohexol Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iohexol Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iohexol Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iohexol Dyspnoea 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Iohexol Erythema 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Iohexol Extravasation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iohexol Feeling hot 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iohexol Flushing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iohexol Headache 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iohexol Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iohexol Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iohexol Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iohexol Hyperthyroidism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iohexol Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iohexol Laryngeal oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iohexol Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iohexol Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iohexol Nasal congestion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Iohexol Nausea 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Iohexol Pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Iohexol Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iohexol Pruritus 0.0 1.0 0.0 0.0 0.0 1.0 1.0 Iohexol Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Iohexol Pyrexia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iohexol Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iohexol Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iohexol Seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Iohexol Shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iohexol Speech disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iohexol Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iohexol Tremor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iohexol Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Iohexol Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iohexol Vomiting 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopamidol Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iopamidol Anaphylactic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopamidol Anaphylactoid reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopamidol Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iopamidol Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopamidol Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopamidol Cyanosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopamidol Depressed level of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iopamidol Dyspnoea 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Iopamidol Flushing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopamidol Hypoaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iopamidol Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopamidol Loss of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopamidol Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopamidol Neurotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Iopamidol Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iopamidol Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iopamidol Urticaria 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Iopamidol Ventricular fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopamidol Visual impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iopamidol Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iopromide Asthenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Brain oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iopromide Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iopromide Chest discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Chest pain 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Chills 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Coma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iopromide Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Cyanosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iopromide Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Dysphagia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Iopromide Dysphonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Dyspnoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Face oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Flushing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Hypotonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iopromide Laryngeal oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Lip swelling 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Loss of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iopromide Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Nervous system disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iopromide Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iopromide Palpitations 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iopromide Pyrexia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iopromide Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Respiratory disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iopromide Respiratory distress 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iopromide Seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Sepsis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iopromide Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Sneezing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Tremor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iopromide Ventricular fibrillation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iopromide Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ioversol Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ioversol Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ioversol Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ioversol Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ioversol Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ioversol Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ioversol Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ioversol Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ioversol Cyanosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ioversol Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ioversol Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ioversol Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ioversol Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ioversol Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ioversol Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ioversol Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ioversol Laryngeal oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ioversol Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ioversol Nasal congestion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ioversol Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ioversol Paraesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ioversol Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ioversol Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ioversol Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ioversol Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ipratropium Asthma 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ipratropium Blood count abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ipratropium Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ipratropium Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ipratropium Cough 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ipratropium Dysphonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ipratropium Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ipratropium Emotional distress 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ipratropium Productive cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ipratropium Wheezing 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ipratropium bromide Asthma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ipratropium bromide Chronic obstructive pulmonary disease 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ipratropium bromide Constipation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ipratropium bromide Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ipratropium bromide Diarrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ipratropium bromide Dizziness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ipratropium bromide Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ipratropium bromide Nasal congestion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ipratropium bromide Sneezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ipratropium bromide Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ipratropium bromide Wheezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Acute pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Affect lability 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Irbesartan Agranulocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Irbesartan Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Irbesartan Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Irbesartan Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Irbesartan Apathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Arrhythmia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Irbesartan Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Irbesartan Asthenia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Irbesartan Atrioventricular block complete 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Atrioventricular block first degree 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Irbesartan Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Blood potassium increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Blood pressure abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Irbesartan Blood pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Irbesartan Blood urea increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Cardiogenic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Irbesartan Cerebrovascular accident 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Irbesartan Chest pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Irbesartan Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Cognitive disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Confusional state 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Irbesartan Coordination abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Irbesartan Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irbesartan Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Depressed mood 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Irbesartan Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Irbesartan Diarrhoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Disturbance in attention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Dizziness 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Irbesartan Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irbesartan Drug interaction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Irbesartan Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Irbesartan Dysphagia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Irbesartan Dyspnoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Irbesartan Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Epistaxis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Irbesartan Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Irbesartan Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Gamma-glutamyltransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Irbesartan Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Hepatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Hot flush 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Hyperbilirubinaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Hyperkalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Hypertensive crisis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Irbesartan Hyperuricaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Hypoaesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Irbesartan Hypocalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Hypothermia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Irbesartan Interstitial lung disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Lactic acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Irbesartan Limb discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Lip swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Irbesartan Loss of consciousness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Irbesartan Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Muscular weakness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Irbesartan Musculoskeletal chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Musculoskeletal stiffness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Nausea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Irbesartan Oedema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Irbesartan Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Orthostatic hypotension 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Irbesartan Pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Irbesartan Palpitations 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Irbesartan Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Paraesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Irbesartan Pharyngeal oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Irbesartan Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Irbesartan Rash erythematous 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Renal failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Renal impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Irbesartan Respiratory distress 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Irbesartan Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Sensory loss 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Irbesartan Sinus bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Somnolence 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Suicidal ideation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Irbesartan Swollen tongue 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Tinnitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Irbesartan Transaminases increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Urinary retention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Irbesartan Vascular purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Irbesartan Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Irbesartan Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Irbesartan Wheezing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Irbesartan White blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irinotecan Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irinotecan Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irinotecan Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Irinotecan Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Irinotecan Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Blood alkaline phosphatase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Blood pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Irinotecan Bone marrow failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irinotecan Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irinotecan Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Deep vein thrombosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Dehydration 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Irinotecan Diarrhoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Irinotecan Disseminated intravascular coagulation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Irinotecan Dyspnoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Enteritis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Irinotecan Fatigue 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Febrile neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Hypokalaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Ileus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Interstitial lung disease 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Leukopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Irinotecan Metastases to liver 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Metastases to lung 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 1.0 Irinotecan Neutrophil count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Irinotecan Oxygen saturation decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irinotecan Pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Pancreatic carcinoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Pancytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Paraesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Irinotecan Paraesthesia oral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irinotecan Platelet count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Pulmonary embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Pyrexia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Irinotecan Rash 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Rhinitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Irinotecan Seizure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Stomatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irinotecan Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Irinotecan Transient ischaemic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irinotecan Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Irinotecan Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Irinotecan White blood cell count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Abdominal pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Asthenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Cerebral infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Cerebrovascular accident 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Dermatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Irinotecan hydrochloride Diarrhoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Dyspnoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Fatigue 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Febrile neutropenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Headache 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Hyperbilirubinaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Irinotecan hydrochloride Hypokalaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Ileus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Intestinal obstruction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Intestinal perforation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Leukopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Liver disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Lung disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Mucosal inflammation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Neutropenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Pulmonary embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Salivary hypersecretion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Skin reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Irinotecan hydrochloride Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Thrombocytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Transaminases increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Irinotecan hydrochloride Weight decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Iron dextran Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron dextran Cardiac arrest 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iron dextran Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iron dextran Dyspnoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Iron dextran Flushing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Iron sucrose Abdominal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iron sucrose Abdominal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iron sucrose Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Iron sucrose Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Anxiety 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Arthralgia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iron sucrose Atrial fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Back pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Blood pressure decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iron sucrose Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iron sucrose Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iron sucrose Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Burning sensation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Chest discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Chills 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iron sucrose Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Cyanosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Death 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Diarrhoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Iron sucrose Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Drug hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Feeling hot 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Fluid overload 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iron sucrose Flushing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iron sucrose Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iron sucrose Haemolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iron sucrose Haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iron sucrose Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Iron sucrose Heart rate increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Hypoaesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Iron sucrose Hypotension 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Iron sucrose Hypoxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iron sucrose Injection site pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Iron sucrose Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Metabolic acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iron sucrose Myocardial infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iron sucrose Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iron sucrose Oxygen saturation decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Iron sucrose Pallor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Iron sucrose Paraesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Iron sucrose Peripheral coldness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Iron sucrose Peritonitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iron sucrose Phlebitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iron sucrose Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iron sucrose Pruritus 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Iron sucrose Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iron sucrose Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Respiratory distress 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Respiratory failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iron sucrose Seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Iron sucrose Swollen tongue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iron sucrose Tremor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Unresponsive to stimuli 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iron sucrose Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Venous thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iron sucrose Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Iron sucrose Weight increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Iron sucrose Wheezing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Isavuconazonium sulfate Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isavuconazonium sulfate Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isavuconazonium sulfate Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isavuconazonium sulfate Transaminases increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Isavuconazonium sulfate Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isoflurane Hyperkalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Isoflurane Hypotension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isoniazid Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isoniazid Acute hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Isoniazid Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isoniazid Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isoniazid Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isoniazid Coagulopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Isoniazid Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isoniazid Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Isoniazid Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isoniazid Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isoniazid Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Isoniazid Drug resistance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isoniazid Drug-induced liver injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Isoniazid Encephalopathy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Isoniazid Generalised tonic-clonic seizure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Isoniazid Hepatic encephalopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Isoniazid Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isoniazid Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Isoniazid Hepatic necrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isoniazid Hepatitis fulminant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Isoniazid Hepatotoxicity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Isoniazid Hyperkalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isoniazid Jaundice 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Isoniazid Lactic acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Isoniazid Liver function test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isoniazid Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isoniazid Metabolic acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isoniazid Pancreatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Isoniazid Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isoniazid Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Isoniazid Rash maculo-papular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isoniazid Renal impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isoniazid Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Isoniazid Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Isoniazid Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Isoniazid Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isoniazid Status epilepticus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isoniazid Stevens-Johnson syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Isoniazid Suicide attempt 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Isoniazid Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isoniazid Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isoniazid Thrombocytopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isoniazid Toxic epidermal necrolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Isoniazid Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isoniazid Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isosorbide mononitrate Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isosorbide mononitrate Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isosorbide mononitrate Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Isosorbide mononitrate Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isosorbide mononitrate Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isosorbide mononitrate Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isosorbide mononitrate Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isosorbide mononitrate Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isotretinoin Abdominal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Abdominal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Abdominal pain upper 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Abscess 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isotretinoin Acne 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isotretinoin Acute myocardial infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isotretinoin Affect lability 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Aggression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Agitation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Alanine aminotransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Amenorrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Amnesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Anger 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Isotretinoin Apathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Isotretinoin Arthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Aspartate aminotransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Back pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Isotretinoin Blood cholesterol increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Blood triglycerides increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Bone pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Cheilitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Chest pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Colitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Colitis ulcerative 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Isotretinoin Confusional state 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Conjunctivitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Constipation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Crohn's disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Crying 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Deafness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Isotretinoin Decreased appetite 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Dehydration 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Depersonalisation/derealisation disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Depressed mood 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Depression 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Isotretinoin Dermatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Diabetic ketoacidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isotretinoin Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Diarrhoea haemorrhagic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Isotretinoin Drug interaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Dry eye 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Isotretinoin Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Dry skin 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Isotretinoin Dysphagia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Isotretinoin Eczema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Emotional disorder 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Isotretinoin Emotional distress 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Isotretinoin Encephalitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isotretinoin Epistaxis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Isotretinoin Erectile dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Erythema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Eye irritation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Eye pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Isotretinoin Fear 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Isotretinoin Fracture 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Gastrointestinal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Haematochezia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Isotretinoin Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isotretinoin Haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Haemorrhoids 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Hallucination 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Hallucination, visual 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Headache 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Isotretinoin Hyperhidrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Hyperkalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Isotretinoin Hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Hypoacusis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Hypoaesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Influenza 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Isotretinoin Intentional self-injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Intracranial pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Irritability 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Irritable bowel syndrome 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Isotretinoin Joint stiffness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Leukopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Libido decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Lip swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Liver function test increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Loss of consciousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Loss of libido 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Malaise 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Mental disorder 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Isotretinoin Migraine 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Isotretinoin Mood altered 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Mood swings 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Muscle atrophy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Musculoskeletal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Isotretinoin Nasal dryness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Nasopharyngitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Nausea 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Isotretinoin Neck pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Neutropenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Nightmare 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Pain 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Isotretinoin Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Pallor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isotretinoin Panic attack 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Paranoia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Personality change 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Photosensitivity reaction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Poor quality sleep 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Proctalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Psychotic disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Pulmonary embolism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Isotretinoin Pyrexia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Rectal haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Rheumatoid arthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Scab 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Sexual dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Skin exfoliation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Sleep disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Somnolence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Staphylococcal infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Stress 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Isotretinoin Suicidal ideation 0.0 1.0 0.0 0.0 0.0 1.0 1.0 Isotretinoin Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Isotretinoin Swelling face 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Thinking abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isotretinoin Unevaluable event 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Vaginal haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Vasculitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Isotretinoin Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Isotretinoin Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin Vomiting 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Weight decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Isotretinoin Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Isotretinoin White blood cell count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Istradefylline Agitation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Istradefylline Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Istradefylline Constipation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Istradefylline Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Istradefylline Decreased appetite 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Istradefylline Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Istradefylline Dyskinesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Istradefylline Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Istradefylline Hallucination 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Istradefylline Hallucination, visual 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Istradefylline Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Istradefylline Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Istradefylline Malaise 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Istradefylline Movement disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Istradefylline Muscular weakness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Istradefylline Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Istradefylline Nightmare 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Istradefylline Parkinson's disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Istradefylline Sleep disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Istradefylline Somnolence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Istradefylline Tremor 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Itraconazole Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Itraconazole Acute kidney injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Itraconazole Alanine aminotransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Itraconazole Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Itraconazole Blood lactate dehydrogenase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Itraconazole Candida infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Itraconazole Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Itraconazole Cardiac failure 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Itraconazole Cardiotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Itraconazole Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Itraconazole Coagulopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Itraconazole Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Itraconazole Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Itraconazole Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Itraconazole Dermatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Itraconazole Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Itraconazole Drug interaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Itraconazole Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Itraconazole Drug resistance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Itraconazole Drug-induced liver injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Itraconazole Dyspnoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Itraconazole Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Itraconazole Erythema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Itraconazole Febrile neutropenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Itraconazole Gastrointestinal disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Itraconazole Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Itraconazole Hallucination 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Itraconazole Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Itraconazole Hepatic enzyme increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Itraconazole Hepatic failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Itraconazole Hepatotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Itraconazole Hyperkalaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Itraconazole Hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Itraconazole Jaundice 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Itraconazole Left ventricular dysfunction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Itraconazole Liver disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Itraconazole Liver function test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Itraconazole Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Itraconazole Muscle spasms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Itraconazole Myopathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Itraconazole Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Itraconazole Neutropenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Itraconazole Oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Itraconazole Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Itraconazole Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Itraconazole Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Itraconazole Pollakiuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Itraconazole Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Itraconazole Pulmonary oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Itraconazole Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Itraconazole Rhabdomyolysis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Itraconazole Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Itraconazole Skin exfoliation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Itraconazole Subdural haematoma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Itraconazole Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Itraconazole Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Itraconazole Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivabradine Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ivabradine Atrioventricular block second degree 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivabradine Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ivabradine Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ivabradine Cardiac failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivabradine Cardiogenic shock 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivabradine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ivabradine Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivabradine Diplopia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ivabradine Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ivabradine Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ivabradine Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ivabradine Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ivabradine Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ivabradine Photophobia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ivabradine Sinus bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivabradine Suicide attempt 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivabradine Torsade de pointes 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ivabradine Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ivabradine Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ivabradine Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ivabradine hydrochloride Atrial fibrillation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ivacaftor Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Alanine aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Asthma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Bacterial infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ivacaftor Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Depression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Ear infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Epilepsy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Epistaxis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Fungal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Gastroenteritis viral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Haemoptysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Hernia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Influenza like illness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Liver function test increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Lower respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Lung disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Lung infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Mental disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Nasal congestion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Oropharyngeal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Pneumothorax 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Productive cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Pulmonary function test decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Pulmonary haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Respiratory disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Respiratory failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Sinus disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Sinusitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Staphylococcal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivacaftor Wheezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivermectin Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivermectin Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivermectin Coma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivermectin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ivermectin Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivermectin Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ivermectin Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivermectin Dysstasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivermectin Eczema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivermectin Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ivermectin Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ivermectin Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivermectin Oedema peripheral 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ivermectin Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivermectin Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivermectin Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivermectin Respiratory distress 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivermectin Stevens-Johnson syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ivermectin Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivosidenib Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivosidenib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ivosidenib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ivosidenib Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivosidenib Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivosidenib Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivosidenib Nausea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ivosidenib Platelet count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivosidenib Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivosidenib Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ivosidenib Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixabepilone Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixabepilone Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixabepilone Pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ixabepilone Vomiting 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ixazomib Abdominal pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Acute kidney injury 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Anaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Asthenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Balance disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Blood count abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Bone marrow failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ixazomib Bone pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ixazomib Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Cardiac failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ixazomib Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Chronic obstructive pulmonary disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Clostridium difficile infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Cognitive disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ixazomib Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Confusional state 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ixazomib Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Dementia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ixazomib Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ixazomib Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Encephalopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Epistaxis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ixazomib Erythema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Erythema multiforme 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Febrile neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Flatulence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ixazomib Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Full blood count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ixazomib Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ixazomib Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Herpes zoster 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Hypocalcaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ixazomib Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Influenza like illness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Intestinal obstruction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ixazomib Joint swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Lip swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Lower respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Lung disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Lung infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Ixazomib Memory impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Myelodysplastic syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ixazomib Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ixazomib Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Nervous system disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Oropharyngeal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ixazomib Pancytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ixazomib Paraesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ixazomib Pericardial effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Plasma cell myeloma 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Ixazomib Platelet count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Pleural effusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Pneumonia aspiration 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Pulmonary embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ixazomib Pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ixazomib Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Rash erythematous 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ixazomib Rash generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Rash pruritic 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ixazomib Red blood cell count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ixazomib Renal disorder 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ixazomib Renal impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ixazomib Respiratory distress 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ixazomib Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ixazomib Respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Sepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Sinusitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Thrombocytopenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Tumour lysis syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ixazomib Upper limb fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Upper respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Visual impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ixazomib White blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketamine Acute kidney injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ketamine Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketamine Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketamine Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ketamine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ketamine Drug abuse 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketamine Hydronephrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ketamine Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketamine Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketamine Urinary tract disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketamine hydrochloride Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ketamine hydrochloride Hypotension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ketamine hydrochloride Respiratory depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ketoconazole Burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ketoconazole Dyspnoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ketoconazole Erythema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ketoconazole Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ketoconazole Hepatotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ketoconazole Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ketoconazole Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ketoconazole Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoconazole Skin exfoliation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ketoprofen Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ketoprofen Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ketoprofen Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ketoprofen Cardiac arrest 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Coma 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Drug abuse 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Drug reaction with eosinophilia and systemic symptoms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Erythema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Gastric ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Generalised tonic-clonic seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Haematemesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Hepatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Hepatitis cholestatic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Hepatocellular injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ketoprofen Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ketoprofen Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ketoprofen Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Liver injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Melaena 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Metabolic acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Pallor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Paraesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Septic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ketoprofen Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Sopor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Suicide attempt 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Vascular purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketoprofen Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketorolac tromethamine Abdominal pain upper 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ketorolac tromethamine Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketorolac tromethamine Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ketorolac tromethamine Confusional state 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ketorolac tromethamine Discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ketorolac tromethamine Eye pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ketorolac tromethamine Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ketorolac tromethamine Gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ketorolac tromethamine Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ketorolac tromethamine Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ketorolac tromethamine Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketorolac tromethamine Loss of consciousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ketorolac tromethamine Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ketorolac tromethamine Oropharyngeal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketorolac tromethamine Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ketorolac tromethamine Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ketorolac tromethamine Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketorolac tromethamine Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ketorolac tromethamine Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ketorolac tromethamine Visual impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ketorolac tromethamine Weight increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Labetalol hydrochloride Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Labetalol hydrochloride Hypotension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lacosamide Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lacosamide Acute kidney injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lacosamide Aggression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lacosamide Altered state of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lacosamide Amnesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lacosamide Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lacosamide Aphasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lacosamide Arrhythmia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lacosamide Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lacosamide Atrial septal defect 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Lacosamide Atrioventricular block 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lacosamide Atrioventricular block complete 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lacosamide Blindness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lacosamide Blood creatine phosphokinase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lacosamide Blood lactate dehydrogenase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lacosamide Blood pressure decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lacosamide Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lacosamide Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lacosamide Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lacosamide Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lacosamide Cerebral infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lacosamide Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lacosamide Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lacosamide Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lacosamide Crying 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lacosamide Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lacosamide Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lacosamide Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lacosamide Disorientation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lacosamide Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lacosamide Dysphagia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lacosamide Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lacosamide Encephalopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lacosamide Epilepsy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lacosamide Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lacosamide Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lacosamide Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lacosamide Gamma-glutamyltransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lacosamide Generalised tonic-clonic seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lacosamide Hallucination 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lacosamide Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lacosamide Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lacosamide Hypothermia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lacosamide Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lacosamide Insomnia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lacosamide Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lacosamide Laceration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lacosamide Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lacosamide Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lacosamide Metabolic acidosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lacosamide Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lacosamide Nausea 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Lacosamide Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lacosamide Nervousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lacosamide Neuropathy peripheral 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lacosamide Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lacosamide Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lacosamide Oropharyngeal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lacosamide Oxygen saturation decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lacosamide Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lacosamide Platelet count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lacosamide Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lacosamide Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lacosamide Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Lacosamide Premature delivery 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lacosamide Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lacosamide Rash generalised 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lacosamide Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lacosamide Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lacosamide Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lacosamide Salivary hypersecretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lacosamide Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lacosamide Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lacosamide Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lacosamide Shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lacosamide Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lacosamide Sopor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lacosamide Status epilepticus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lacosamide Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lacosamide Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lacosamide Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lacosamide Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lacosamide Ventricular fibrillation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lacosamide Ventricular tachycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lacosamide Vomiting 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Lacosamide Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lacosamide White blood cell count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lactulose Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lactulose Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lactulose Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lactulose Dyspnoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lactulose Hepatic encephalopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lactulose Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamivudine Abdominal discomfort 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamivudine Abdominal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamivudine Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamivudine Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamivudine Anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamivudine Angioedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamivudine Aspartate aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamivudine Atrial septal defect 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Lamivudine Blood bilirubin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamivudine Blood creatinine increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamivudine Bone marrow failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamivudine Confusional state 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamivudine Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamivudine Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamivudine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamivudine Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamivudine Dehydration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamivudine Depression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamivudine Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamivudine Discomfort 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamivudine Drug interaction 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamivudine Drug resistance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamivudine Drug-induced liver injury 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Lamivudine Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamivudine Dysphonia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamivudine Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamivudine Foetal death 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Lamivudine Gynaecomastia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamivudine Hallucination 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamivudine Hepatic encephalopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamivudine Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamivudine Hepatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamivudine Hepatomegaly 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamivudine Hepatotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamivudine Hypercholesterolaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamivudine Hypophosphataemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamivudine Hypotension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamivudine Influenza 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamivudine Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamivudine Intervertebral disc protrusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamivudine Jaundice 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamivudine Lactic acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamivudine Leukopenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamivudine Malnutrition 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamivudine Maternal drugs affecting foetus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamivudine Metabolic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamivudine Movement disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamivudine Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamivudine Nephropathy toxic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamivudine Nervous system disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamivudine Neurotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamivudine Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamivudine Nightmare 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamivudine Osteoporosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamivudine Pancytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamivudine Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamivudine Pollakiuria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamivudine Premature baby 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Lamivudine Premature delivery 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamivudine Proteinuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamivudine Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamivudine Pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamivudine Renal failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamivudine Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamivudine Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamivudine Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamivudine Skin exfoliation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamivudine Sleep disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamivudine Splenomegaly 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Lamivudine Suicidal ideation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamivudine Thrombocytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamivudine Transaminases increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamivudine Treatment failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamivudine Viral infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamivudine Vomiting 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Abdominal discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Abdominal distension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Abdominal pain upper 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Abdominal tenderness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Abnormal dreams 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamotrigine Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamotrigine Acidosis 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Lamotrigine Acute generalised exanthematous pustulosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Acute hepatic failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Acute respiratory distress syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Acute respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Affect lability 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Lamotrigine Aggression 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Lamotrigine Agitation 0.0 1.0 1.0 0.0 1.0 0.0 0.0 Lamotrigine Agranulocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Akathisia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Alanine aminotransferase increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Lamotrigine Altered state of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Amnesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Anaemia 0.0 1.0 1.0 0.0 1.0 0.0 0.0 Lamotrigine Anger 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Lamotrigine Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Anxiety 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Lamotrigine Aphasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Apnoea 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Lamotrigine Arthralgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Ascites 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Lamotrigine Aspartate aminotransferase increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Asthenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Asthma 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Lamotrigine Ataxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Atelectasis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Atrial fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Atrial septal defect 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Lamotrigine Atrioventricular block 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Atrioventricular block complete 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Back pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Balance disorder 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Lamotrigine Blepharitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Blindness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Blister 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Blood bilirubin increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Blood creatine phosphokinase increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Blood creatinine increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Blood glucose increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Blood lactate dehydrogenase increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Blood pressure decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Blood pressure increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Blood urea increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Body temperature increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Bone marrow failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Bradyphrenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamotrigine Brain oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Bronchitis 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Lamotrigine Burning sensation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine C-reactive protein increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Cardiac disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Cardiac failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Cardiac murmur 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Lamotrigine Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Cheilitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Chest discomfort 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Chest pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Chills 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Choking 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamotrigine Cholelithiasis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Circulatory collapse 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Cognitive disorder 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Lamotrigine Colitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Coma 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Confusional state 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Lamotrigine Conjunctival hyperaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Conjunctivitis 0.0 1.0 1.0 0.0 1.0 0.0 0.0 Lamotrigine Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Coordination abnormal 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Lamotrigine Cough 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Crying 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Cyanosis 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Lamotrigine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Decreased appetite 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Dehydration 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Lamotrigine Delirium 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Delusion 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Dementia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Depressed level of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Dermatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Dermatitis allergic 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Dermatitis bullous 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Dermatitis exfoliative 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Diarrhoea haemorrhagic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Diplopia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Disseminated intravascular coagulation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Disturbance in attention 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Lamotrigine Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Drug eruption 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Drug hypersensitivity 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Drug interaction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Drug intolerance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Drug withdrawal syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Dry eye 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Dysarthria 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Lamotrigine Dysgeusia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Dyskinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Dysmenorrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Dysphagia 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Lamotrigine Dyspnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Dystonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Dysuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Ear disorder 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Lamotrigine Ear infection 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Lamotrigine Eating disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Ecchymosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Eczema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Ejection fraction decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Electrocardiogram abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Emotional disorder 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Lamotrigine Emotional distress 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Encephalopathy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Enteritis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Epilepsy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamotrigine Erythema 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Erythema multiforme 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Eye irritation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Eye pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Eye pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Eyelid oedema 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Face oedema 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Fatigue 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Lamotrigine Fear 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Febrile neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Feeding disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Feeling abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Feeling hot 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Feeling jittery 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Flushing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Foetal death 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Lamotrigine Foetal growth restriction 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Lamotrigine Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Gastrointestinal disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Gastrooesophageal reflux disease 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Lamotrigine Generalised oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Generalised tonic-clonic seizure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Glossodynia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Haematocrit decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Haemodynamic instability 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Haemoglobin decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Haemolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Haemolytic anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Haemoptysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Hallucination, auditory 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Heart rate decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Heart rate increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Hemiplegia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Hepatic encephalopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Hepatic enzyme increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Hepatic function abnormal 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Hepatic steatosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Hepatitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Hepatocellular injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Hepatomegaly 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Hepatotoxicity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Hot flush 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamotrigine Hydronephrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Hyperbilirubinaemia 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Lamotrigine Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Hypernatraemia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Hyperreflexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Hypersensitivity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Hypersensitivity vasculitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Hyperthermia 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Lamotrigine Hypertonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Hyperventilation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Hypoacusis 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Lamotrigine Hypoaesthesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Hypoalbuminaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Hypoglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Hypokinesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Hypophagia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Hyporeflexia 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Lamotrigine Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Hypothermia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Hypotonia 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Lamotrigine Hypoxia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Inappropriate antidiuretic hormone secretion 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Increased appetite 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Lamotrigine Infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Inflammation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Influenza like illness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Intentional self-injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Interstitial lung disease 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Intracranial pressure increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Irritability 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Lacrimation increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Lethargy 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Leukocytosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Lip swelling 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Liver disorder 0.0 0.0 1.0 0.0 1.0 0.0 0.0 Lamotrigine Liver function test increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Liver injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Lung disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Lung infiltration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Lymphadenopathy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Lymphopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Malaise 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Lamotrigine Malnutrition 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Mania 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Maternal drugs affecting foetus 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Lamotrigine Memory impairment 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Lamotrigine Meningitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Menorrhagia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Mental disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Mental status changes 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Metabolic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Metrorrhagia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamotrigine Middle insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Mobility decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Mood altered 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Mood swings 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Motor dysfunction 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Lamotrigine Mouth ulceration 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Lamotrigine Mucosal inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Muscle rigidity 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Muscle spasms 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Muscle tightness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Muscle twitching 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Muscular weakness 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Lamotrigine Musculoskeletal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Musculoskeletal stiffness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Myalgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Mydriasis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Myocarditis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Myoclonus 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Lamotrigine Myositis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Nasal congestion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Nasopharyngitis 0.0 0.0 1.0 1.0 1.0 0.0 0.0 Lamotrigine Nausea 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Lamotrigine Neck pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Necrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Neuroleptic malignant syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Neurological symptom 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Neurotoxicity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Neutropenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Night sweats 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Nightmare 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Nystagmus 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Ocular hyperaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Oedema 0.0 1.0 1.0 0.0 1.0 0.0 0.0 Lamotrigine Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Oral disorder 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Oral pain 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Lamotrigine Oropharyngeal discomfort 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Lamotrigine Oropharyngeal pain 0.0 1.0 1.0 0.0 1.0 0.0 0.0 Lamotrigine Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Osteonecrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Osteoporosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Otitis media 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Lamotrigine Oxygen saturation decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Pallor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Palpitations 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Pancreatitis 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Pancreatitis acute 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Pancytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Panic attack 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Paralysis 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Lamotrigine Paranoia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Pericardial effusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Pericarditis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Periorbital oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Personality change 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Personality disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamotrigine Petechiae 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Pharyngeal oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Pharyngitis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Photophobia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Photosensitivity reaction 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Pigmentation disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Platelet count decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Pleural effusion 0.0 1.0 1.0 0.0 1.0 0.0 0.0 Lamotrigine Pneumonia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Pneumonia aspiration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Pneumonitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Polyneuropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamotrigine Poor quality sleep 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamotrigine Posterior reversible encephalopathy syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Lamotrigine Premature delivery 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamotrigine Proteinuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Pruritus 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Lamotrigine Pruritus generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Pseudomembranous colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Psychomotor hyperactivity 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Lamotrigine Pulmonary embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Pulmonary function test decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Pulmonary hypertension 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Lamotrigine Purpura 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Rash 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Lamotrigine Rash erythematous 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Rash generalised 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Rash macular 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Rash maculo-papular 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Rash papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Rash pruritic 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Red blood cell count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Renal disorder 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Lamotrigine Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Renal impairment 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Lamotrigine Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Respiratory depression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Respiratory disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Respiratory distress 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Retching 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamotrigine Rhabdomyolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Rhinitis 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Lamotrigine Rhinorrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Scab 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Sedation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Seizure 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Lamotrigine Sepsis 1.0 1.0 0.0 0.0 1.0 0.0 0.0 Lamotrigine Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Serotonin syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Sinus tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Skin burning sensation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Skin discolouration 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Skin disorder 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Lamotrigine Skin exfoliation 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Lamotrigine Skin hyperpigmentation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Skin lesion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Skin necrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Sleep disorder 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Lamotrigine Sluggishness 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Lamotrigine Somnolence 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Lamotrigine Sopor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Speech disorder 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Lamotrigine Splenomegaly 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Staphylococcal infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Status epilepticus 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Stevens-Johnson syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Stomatitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Stupor 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Suicidal ideation 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Lamotrigine Suicide attempt 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Swelling face 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Swollen tongue 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Syncope 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Systemic lupus erythematosus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Tachypnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Thirst 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Throat tightness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Thrombocytopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Thrombosis 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Tooth disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamotrigine Toxic epidermal necrolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Toxic skin eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Transaminases increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Treatment failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lamotrigine Tremor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Ulcer 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Unresponsive to stimuli 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Urinary incontinence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Urinary tract infection 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Lamotrigine Urticaria 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Lamotrigine Ventricular fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine Vertigo 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Lamotrigine Viral infection 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Vision blurred 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Visual acuity reduced 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Visual field defect 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Visual impairment 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Lamotrigine Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Weight decreased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lamotrigine White blood cell count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lamotrigine White blood cell count increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lamotrigine Withdrawal syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lanreotide Alopecia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lanreotide Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lanreotide Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lanreotide Flatulence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lanreotide Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lanreotide Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lanreotide acetate Abdominal pain 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Lanreotide acetate Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lanreotide acetate Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lanreotide acetate Asthenia 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Lanreotide acetate Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lanreotide acetate Cardiac disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lanreotide acetate Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lanreotide acetate Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lanreotide acetate Cholecystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lanreotide acetate Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lanreotide acetate Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lanreotide acetate Decreased appetite 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Lanreotide acetate Diabetes mellitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lanreotide acetate Discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lanreotide acetate Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lanreotide acetate Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lanreotide acetate Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lanreotide acetate Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lanreotide acetate Flatulence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lanreotide acetate Gallbladder disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lanreotide acetate Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lanreotide acetate Hepatobiliary disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lanreotide acetate Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lanreotide acetate Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lanreotide acetate Leukopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lanreotide acetate Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lanreotide acetate Malnutrition 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lanreotide acetate Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lanreotide acetate Myocardial infarction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lanreotide acetate Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lanreotide acetate Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lanreotide acetate Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lanreotide acetate Tinnitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lanreotide acetate Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lanreotide acetate Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lanreotide acetate Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Abdominal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Abdominal distension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Abdominal pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Abdominal pain upper 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Abnormal faeces 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Acute coronary syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Acute kidney injury 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Acute respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Ageusia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Agranulocytosis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Alanine aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Albuminuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Amnesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Anal incontinence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Lansoprazole Aphthous ulcer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Asthenia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Lansoprazole Asthma 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Atrial fibrillation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Balance disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Blood alkaline phosphatase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Blood bilirubin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Blood cholesterol increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Blood creatine phosphokinase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Blood creatinine increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Blood disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Blood magnesium decreased 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Lansoprazole Blood potassium decreased 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Lansoprazole Blood pressure decreased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Bone disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Bone pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Bradyphrenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Brain oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Burning sensation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole C-reactive protein increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Cardiac failure acute 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Cardiopulmonary failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Chest discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Chest pain 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Lansoprazole Chills 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Chromaturia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Chronic kidney disease 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Clostridium difficile colitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Clostridium difficile infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Cold sweat 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Colitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Colitis ulcerative 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Confusional state 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Lansoprazole Conjunctivitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Contusion 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Coronary artery disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Cough 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Lansoprazole Deafness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Deep vein thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Dementia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Depressed mood 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Depression 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Lansoprazole Diabetes mellitus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Drug abuse 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Drug eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Drug hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Drug intolerance 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Drug reaction with eosinophilia and systemic symptoms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Drug-induced liver injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Dry skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Dysgeusia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Dysphonia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Dyspnoea 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Lansoprazole Dysuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Eczema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Electrocardiogram QT prolonged 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Electrolyte imbalance 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Eosinophilia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Epilepsy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Epistaxis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Eructation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Erythema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Eye pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Face oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Lansoprazole Febrile neutropenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Feeding disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Feeling abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Feeling cold 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Flatulence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Flushing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Gait disturbance 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Gamma-glutamyltransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Gastric cancer 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Gastric ulcer 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Gastritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Gastrointestinal pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Gastrooesophageal reflux disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Generalised tonic-clonic seizure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Gingival bleeding 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Haematemesis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Haematuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Haemoglobin decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Hallucination 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Headache 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Lansoprazole Heart rate decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Hepatic steatosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Hepatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Hyperbilirubinaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Hyperhidrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Hyperkalaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Hypertension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Hypocalcaemia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Lansoprazole Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Hypomagnesaemia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Lansoprazole Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Hypoxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Ill-defined disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Immune thrombocytopenic purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Inappropriate antidiuretic hormone secretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Intentional self-injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Interstitial lung disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Irritable bowel syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Joint stiffness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Lactic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Lethargy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Lip swelling 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Liver function test abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Loss of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Malaise 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Metabolic acidosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Micturition urgency 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Mood swings 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Mouth ulceration 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Muscular weakness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Musculoskeletal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Musculoskeletal stiffness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Neck pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Nephrolithiasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Nocturia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Nodule 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Oesophagitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Oliguria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Oral pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Osteoporosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Oxygen saturation decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Palpitations 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Pancreatitis acute 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Panic attack 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Pelvic pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Peripheral swelling 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Pharyngeal oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Photophobia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Photosensitivity reaction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Pneumonia 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Pollakiuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Polyuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Pruritus generalised 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Pulmonary embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Rash macular 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Rash pustular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Rectal haemorrhage 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Renal disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Renal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Skin discolouration 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Sleep disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Sopor 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Stevens-Johnson syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Stomatitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Subdural haematoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Suicidal ideation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Suicide attempt 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Swelling face 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Swollen tongue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Tenderness 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Throat tightness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Tooth disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Torsade de pointes 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Toxic epidermal necrolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Toxic skin eruption 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Tubulointerstitial nephritis 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Urinary incontinence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Urticaria 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Lansoprazole Vertigo 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lansoprazole Viral infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole Vomiting 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lansoprazole Weight decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lansoprazole Wheezing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lansoprazole White blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lanthanum carbonate Abdominal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lanthanum carbonate Atrial fibrillation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lanthanum carbonate Cardiac disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lanthanum carbonate Constipation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lanthanum carbonate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lanthanum carbonate Decreased appetite 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lanthanum carbonate Gastric ulcer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lanthanum carbonate Large intestine perforation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lanthanum carbonate Medication residue present 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lanthanum carbonate Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lanthanum carbonate Peritonitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lanthanum carbonate Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lapatinib Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lapatinib Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lapatinib Bone pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lapatinib Breast cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lapatinib Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lapatinib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lapatinib Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lapatinib Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lapatinib Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lapatinib Febrile neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lapatinib Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lapatinib Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lapatinib Metastases to central nervous system 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lapatinib Metastases to lung 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lapatinib Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lapatinib Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lapatinib Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lapatinib Pulmonary embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lapatinib Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lapatinib Thrombocytopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lapatinib Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lapatinib Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Larotrectinib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Larotrectinib Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Larotrectinib Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Larotrectinib Metastases to lung 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Larotrectinib Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Larotrectinib Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Larotrectinib Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Latanoprost Abasia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Arrhythmia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Latanoprost Arthritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Latanoprost Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Latanoprost Blindness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Blood pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Chest discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Latanoprost Cough 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Latanoprost Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Latanoprost Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Diarrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Disease progression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Latanoprost Drug hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Dry eye 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Dyspnoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Latanoprost Eye disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Eye haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Eye irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Eye pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Eye pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Eyelid oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Feeling abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Latanoprost Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Headache 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Latanoprost Heart rate increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Hypoacusis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Latanoprost Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Latanoprost Intraocular pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Lacrimation increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Latanoprost Memory impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Mobility decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Latanoprost Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Latanoprost Nervousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Ocular hyperaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Palpitations 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Latanoprost Photophobia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Latanoprost Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Retinal detachment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Swelling face 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Tinnitus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Latanoprost Tremor 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Upper limb fracture 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Urinary tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Latanoprost Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Visual acuity reduced 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Visual field defect 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprost Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Latanoprostene bunod Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Latanoprostene bunod Intraocular pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Abdominal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Abdominal distension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leflunomide Abdominal pain 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Abdominal pain upper 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Acute hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Acute kidney injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Acute respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Agranulocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Alanine aminotransferase increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leflunomide Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Anaphylactic reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Anaphylactic shock 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Angina pectoris 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Angioedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Aphthous ulcer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Arthritis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Arthropathy 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Ascites 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Aspartate aminotransferase increased 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Leflunomide Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Asthma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Back pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Blister 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Leflunomide Blood bilirubin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leflunomide Blood cholesterol increased 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Blood creatine phosphokinase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leflunomide Blood creatinine increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leflunomide Blood glucose increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Blood pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Body temperature increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Bone disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leflunomide Bone marrow failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Bronchitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Bursitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Leflunomide C-reactive protein increased 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Candida infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Cellulitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Cerebral haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leflunomide Cerebrovascular accident 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leflunomide Chest discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Chest pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leflunomide Chills 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leflunomide Chronic kidney disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Chronic obstructive pulmonary disease 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leflunomide Coagulopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Colitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Confusional state 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Constipation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Contusion 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Crohn's disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Cyst 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leflunomide Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leflunomide Deep vein thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leflunomide Delirium 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Leflunomide Depression 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Dermatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leflunomide Dermatitis allergic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leflunomide Disease progression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Disseminated intravascular coagulation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Drug hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Drug intolerance 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Drug-induced liver injury 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Dry mouth 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Dry skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Dyspnoea 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Dysstasia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Encephalitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Encephalopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Epistaxis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Erythema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leflunomide Eye disorder 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Feeling abnormal 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Feeling hot 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Femur fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leflunomide Flatulence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Flushing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Gastric disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Gastric ulcer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Gastrointestinal disorder 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Gastrooesophageal reflux disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Haemoglobin decreased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Leflunomide Headache 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Hepatic cirrhosis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Hepatic enzyme abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leflunomide Hepatic enzyme increased 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Hepatic steatosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Hepatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Hepatotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Herpes zoster 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Hypercalcaemia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Leflunomide Hyperhidrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leflunomide Hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Hypertension 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Hypertensive crisis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Hypoacusis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leflunomide Hypotension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Leflunomide Hypoxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Ill-defined disorder 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Infection 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Inflammation 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Influenza 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Influenza like illness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Injury 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Leflunomide Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Interstitial lung disease 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Iron deficiency anaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Jaundice 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Leflunomide Joint stiffness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Joint swelling 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Laboratory test abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Leukocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Leukopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Lip swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Liver disorder 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Liver function test abnormal 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Liver function test increased 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Liver injury 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Leflunomide Local swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Loss of consciousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Lower respiratory tract infection 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Lung disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Lung infiltration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leflunomide Lung neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Lymphadenopathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Lymphoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Malaise 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Metabolic acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Migraine 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Mouth ulceration 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Muscle spasms 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Muscular weakness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Musculoskeletal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Musculoskeletal pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Musculoskeletal stiffness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Nasopharyngitis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Nausea 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Neck pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Nephrolithiasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Nervous system disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Neuralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Neutropenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Night sweats 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Nodule 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Oedema 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Leflunomide Oedema peripheral 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Oral candidiasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Oral discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Oropharyngeal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Osteoarthritis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Osteomyelitis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Osteonecrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leflunomide Pericarditis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Leflunomide Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Pharyngeal oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Pharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leflunomide Platelet count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Pleurisy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leflunomide Pneumonia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Pneumonitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Pneumothorax 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Pollakiuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leflunomide Polyneuropathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leflunomide Posterior reversible encephalopathy syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leflunomide Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Leflunomide Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Psoriasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Pulmonary embolism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Pulmonary fibrosis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Pulmonary mass 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Pyrexia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leflunomide Rash 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Rash macular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Rash maculo-papular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Rash pruritic 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leflunomide Red blood cell count decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leflunomide Red blood cell sedimentation rate increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Leflunomide Renal disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Renal failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Respiratory disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Respiratory tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Rheumatoid arthritis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Sepsis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Sinusitis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Skin cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Skin disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Skin infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Skin mass 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Skin ulcer 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Leflunomide Sleep disorder 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Somnolence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leflunomide Splenomegaly 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Squamous cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Stevens-Johnson syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Stomatitis 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Subarachnoid haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leflunomide Swelling 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Swollen tongue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Systemic lupus erythematosus 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Tenderness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Tendonitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leflunomide Throat tightness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Leflunomide Tooth abscess 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Tooth disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leflunomide Transaminases increased 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Treatment failure 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Tremor 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Ulcer 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Leflunomide Unevaluable event 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Upper respiratory tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Urinary tract infection 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Urosepsis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Urticaria 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Vasculitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Vertigo 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Vomiting 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide Weight decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leflunomide Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leflunomide White blood cell count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leflunomide White blood cell count increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lenalidomide Abasia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Lenalidomide Abdominal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Abdominal distension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Abdominal pain lower 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Abnormal faeces 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Abscess 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Acute coronary syndrome 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Acute generalised exanthematous pustulosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Acute hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Acute myeloid leukaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Acute myocardial infarction 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Acute pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Acute respiratory failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Ageusia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Agitation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Agranulocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Alanine aminotransferase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Altered state of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Amnesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Amylase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Anaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Anger 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Angina pectoris 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Angiopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Aphasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Aphthous ulcer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Aplastic anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Appendicitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Arrhythmia supraventricular 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Arthritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Arthropathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Ascites 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Aspartate aminotransferase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Aspiration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Asthma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Ataxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Atelectasis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Atrial flutter 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Atrioventricular block 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Atrioventricular block complete 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Atrioventricular block second degree 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Azotaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Bacteraemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Bacterial infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Basal cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Blindness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Lenalidomide Blister 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Blood albumin decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Blood alkaline phosphatase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Blood bilirubin increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Blood count abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Blood creatine phosphokinase increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lenalidomide Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Blood disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Blood glucose decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Blood lactate dehydrogenase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Blood magnesium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Blood potassium increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Blood pressure abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Blood pressure decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Blood urea increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Blood uric acid increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Blood urine present 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Bone disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Bone marrow failure 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Brain injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Brain oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Breast disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Bronchospasm 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Bursitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide C-reactive protein increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Cachexia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Candida infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Cardiac disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Cardiac failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Cardiac failure acute 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Cardiac failure congestive 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Cardiac murmur 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Cardiac tamponade 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Cardiogenic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Cardiomyopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Cardiopulmonary failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Cardiotoxicity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Cardiovascular disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Carpal tunnel syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Cerebral haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Cerebral infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Cerebral ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Cerebrovascular accident 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Chest discomfort 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Choking 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Cholangitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Cholecystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Cholecystitis acute 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Cholestasis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Chronic kidney disease 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Lenalidomide Chronic obstructive pulmonary disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Circulatory collapse 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Clostridium difficile colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Clostridium difficile infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Coagulopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Cognitive disorder 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Lenalidomide Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Colitis ischaemic 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Colitis ulcerative 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Colon cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Coma 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Confusional state 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Congestive cardiomyopathy 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lenalidomide Constipation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Contusion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Coronary artery disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Cystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Decubitus ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Deep vein thrombosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Delirium 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Delusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Dementia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Depressed level of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Dermatitis allergic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Dermatitis bullous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Diabetic ketoacidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Diarrhoea haemorrhagic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Diplopia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Disease recurrence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Disorientation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Disseminated intravascular coagulation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Diverticulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Drug eruption 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Drug hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Drug resistance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Dry eye 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Dry skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Dry throat 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Duodenal ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Dysgeusia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Dysphagia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Dysstasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Eating disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Ecchymosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Ejection fraction decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Embolism venous 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Encephalitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Encephalopathy 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Enteritis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Enterocolitis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Epilepsy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Epistaxis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Erythema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Erythema multiforme 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Eye disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Eye haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Faecaloma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Faeces discoloured 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Failure to thrive 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Febrile neutropenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Feeding disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Feeling abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Feeling hot 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Femur fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Flank pain 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Lenalidomide Flatulence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Fluid overload 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Fluid retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Full blood count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Gallbladder disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Gamma-glutamyltransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Gastric cancer 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Gastric disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Gastric haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Gastric ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Gastritis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Gastroenteritis viral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Gastrointestinal disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Gastrointestinal haemorrhage 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Generalised tonic-clonic seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Gout 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Haematemesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Haematochezia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Haematocrit decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Haemolysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Haemolytic anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Haemorrhage intracranial 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Haemorrhagic stroke 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Heart rate decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Heart rate irregular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Hemiparesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Hemiplegia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Hepatic cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Hepatic cirrhosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Hepatic encephalopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Hepatic function abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Hepatitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Hepatotoxicity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Herpes zoster 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Hiccups 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Hip fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Hot flush 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Hydronephrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Hyperaesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Hyperbilirubinaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Hypercalcaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Hyperglycaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Hyperkalaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Hyperlipidaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Hyperthermia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Hyperuricaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Hypoacusis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Hypoaesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Hypoalbuminaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Hypocalcaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Hypoglycaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Hypokalaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Hypomagnesaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Hyponatraemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Hypophosphataemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Hypothyroidism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Hypovolaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Hypoxia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Ileus 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Ileus paralytic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Ill-defined disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Immune system disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Inappropriate antidiuretic hormone secretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Incontinence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Influenza like illness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Inner ear disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Interstitial lung disease 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Intervertebral disc protrusion 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lenalidomide Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Intestinal perforation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Intraocular pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Irritability 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lenalidomide Ischaemic stroke 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Lenalidomide Jaundice 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Jaundice cholestatic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Joint swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Laboratory test abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Laceration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Lacrimation increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Lactic acidosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Large intestine perforation 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Laryngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Left ventricular dysfunction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Lethargy 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Leukocytosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Leukopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Libido decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Liver disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Liver function test abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Liver function test increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Localised infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Lower respiratory tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Lung disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Lung infection 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Lung infiltration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Lymphocyte count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Lymphoedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Lymphoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Lymphopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Malignant melanoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Malnutrition 1.0 1.0 1.0 1.0 0.0 0.0 0.0 Lenalidomide Melaena 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Memory impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Meningitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Mental disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Mental status changes 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Metabolic acidosis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Metabolic disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Metastases to central nervous system 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Metastases to liver 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Metastatic neoplasm 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Micturition disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Mobility decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Movement disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Mucosal inflammation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Muscle atrophy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Muscle spasms 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Muscle twitching 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Musculoskeletal chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Musculoskeletal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Myelodysplastic syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Myocardial infarction 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Myocardial ischaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Myocarditis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Myopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Nasal congestion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Nasopharyngitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Neck pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Neoplasm 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Nephropathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Nephropathy toxic 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Nervous system disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Neurotoxicity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Neutropenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Neutrophil count decreased 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Nightmare 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Oesophageal ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Oesophagitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Oral candidiasis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Oral disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Oral pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Osteoarthritis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Lenalidomide Osteomyelitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Osteonecrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Osteonecrosis of jaw 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Oxygen saturation decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Pancreatic carcinoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Pancreatitis acute 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Pancytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Paraesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Paralysis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lenalidomide Parkinson's disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Pelvic pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Peptic ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Pericardial effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Pericarditis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Peripheral coldness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Peripheral ischaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Peripheral sensory neuropathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 1.0 Lenalidomide Peritonitis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Pharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Plasma cell myeloma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Platelet count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Pleural effusion 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Pleurisy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Pneumocystis jirovecii pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Pneumonia aspiration 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Pneumonia bacterial 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Pneumonitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Pneumothorax 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Polyneuropathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Posterior reversible encephalopathy syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Proctalgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Productive cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Prostate cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Pruritus generalised 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Psychotic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Pulmonary alveolar haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Pulmonary embolism 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Pulmonary fibrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Pulmonary haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Pulmonary hypertension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Pulmonary mass 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Pulmonary oedema 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Purpura 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Pyelonephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Rash 0.0 0.0 0.0 0.0 0.0 1.0 1.0 Lenalidomide Rash macular 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Lenalidomide Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Rash papular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Rash pruritic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Rash pustular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Red blood cell count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Renal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Renal failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Renal impairment 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Renal tubular necrosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Respiratory disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Respiratory distress 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Respiratory failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Respiratory tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Retinal haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Rhinorrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Sciatica 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Sepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Septic shock 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Shock haemorrhagic 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Sinus bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Sinus congestion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Sinusitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Skin cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Skin discolouration 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Skin disorder 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Skin exfoliation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Skin infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Skin irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Skin reaction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Skin ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Sleep apnoea syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Sleep disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Small intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Speech disorder 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Spinal compression fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Spinal fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Splenomegaly 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Squamous cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Staphylococcal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Stevens-Johnson syndrome 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Stress 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Stress cardiomyopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Subarachnoid haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Subdural haematoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Suicide attempt 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Supraventricular tachycardia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Swelling face 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Tachycardia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Tachypnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Tenderness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Thrombophlebitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Thrombosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Thrombotic thrombocytopenic purpura 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Tinnitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Tongue disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Tooth disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Torsade de pointes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Toxic epidermal necrolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Toxic skin eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Transaminases increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Transient ischaemic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Treatment failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Troponin increased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Tumour lysis syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Unevaluable event 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Unresponsive to stimuli 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Upper gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Upper limb fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Upper respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Urinary tract disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Urine abnormality 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Urine output decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Urosepsis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Vaginal haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Vascular purpura 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Vasculitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Venous thrombosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Ventricular fibrillation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenalidomide Ventricular tachycardia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Visual acuity reduced 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lenalidomide Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide Wheezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenalidomide White blood cell count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lenalidomide White blood cell count increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Abdominal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Abdominal pain lower 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Abscess 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Acute myeloid leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenvatinib Acute myocardial infarction 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenvatinib Alanine aminotransferase increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Alopecia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Altered state of consciousness 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Amnesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Amylase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Anaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Angina pectoris 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Aphthous ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Appendicitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Ascites 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Aspartate aminotransferase increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Asphyxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenvatinib Aspiration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Bacteraemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Blister 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Blood albumin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Blood alkaline phosphatase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenvatinib Blood bilirubin increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Blood count abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Blood lactate dehydrogenase increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Blood pressure decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Blood pressure fluctuation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Blood urea increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Blood urine present 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Bone pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Brain oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib C-reactive protein increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenvatinib Cardiac disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Cardiac failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Cardiac failure acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Cardiac tamponade 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenvatinib Cardiogenic shock 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Cardiomyopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Cerebral haemorrhage 1.0 1.0 1.0 1.0 0.0 0.0 0.0 Lenvatinib Cerebral infarction 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Cerebral ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Cerebrovascular accident 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Cholangitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Cholecystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Cholecystitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Coagulopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Cognitive disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Colitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Contusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Coronary artery disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenvatinib Decreased appetite 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Decubitus ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Deep vein thrombosis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Delirium 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Depressed level of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Depression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Dermatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Diabetes mellitus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Diarrhoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Disease progression 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Disseminated intravascular coagulation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenvatinib Disturbance in attention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Diverticulitis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Drug eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Drug-induced liver injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Dry eye 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Dry mouth 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Dry skin 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Duodenal ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Dysgeusia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Dyskinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Dyspepsia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Dysphagia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Dysphonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Dyspnoea exertional 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Ejection fraction decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenvatinib Encephalitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Encephalopathy 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Enterocolitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Epigastric discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Epilepsy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenvatinib Epistaxis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Erythema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Erythema multiforme 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Febrile neutropenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Feeling abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Feeling cold 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Flank pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Gastric haemorrhage 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Gastrointestinal haemorrhage 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Generalised oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Gingival bleeding 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Gingivitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Glossitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Glossodynia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Haematemesis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Haematochezia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Haematuria 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Haemoptysis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Haemorrhage 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Haemorrhage intracranial 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Haemorrhoids 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Hepatic cirrhosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Hepatic encephalopathy 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Hepatic enzyme increased 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Lenvatinib Hepatic failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Hepatic function abnormal 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Hepatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Hepatotoxicity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Herpes zoster 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Hyperbilirubinaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Hypercalcaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Hyperglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Hyperkalaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Hypertension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Hypertensive crisis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Hyperthyroidism 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Hypoaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Hypoalbuminaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Hypocalcaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Hypoglycaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Hypokalaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Hypomagnesaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Hypothyroidism 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Hypoxia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Ileus 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Interstitial lung disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Intestinal perforation 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Ischaemic stroke 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Jaundice 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Jaundice cholestatic 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Large intestine perforation 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Lipase increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Liver disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Liver function test increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Lung disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Lung infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Malaise 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Malignant neoplasm progression 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Malnutrition 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Melaena 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Metastases to central nervous system 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Metastases to lung 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Mouth ulceration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Mucosal inflammation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenvatinib Muscle spasms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Musculoskeletal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Myalgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Myocardial infarction 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Neck pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Nephrotic syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Neuropathy peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Neutrophil count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Oedema peripheral 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Oral discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Oral pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Oropharyngeal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Osteomyelitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Pericardial effusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Peritonitis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Platelet count decreased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Pleural effusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Pneumocystis jirovecii pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Pneumonia aspiration 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Pneumonia bacterial 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Pneumonitis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Pneumothorax 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Posterior reversible encephalopathy syndrome 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Protein urine present 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Proteinuria 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Pulmonary embolism 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Pulmonary haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Pyelonephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Pyrexia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Rash generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Rash macular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Rash pruritic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Renal disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Renal failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Renal impairment 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Respiratory distress 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lenvatinib Seizure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Sepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Septic shock 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenvatinib Shock haemorrhagic 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenvatinib Skin disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Skin ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Spinal compression fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Stomatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Subarachnoid haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenvatinib Subdural haematoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenvatinib Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenvatinib Supraventricular tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Thirst 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Thrombocytopenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Tooth abscess 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Toxic skin eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Transaminases increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Transient ischaemic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Tumour lysis syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lenvatinib Upper gastrointestinal haemorrhage 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Upper respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Urticaria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Vaginal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Vision blurred 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Weight increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib Wheezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib White blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lenvatinib White blood cell count increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Letermovir Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Letermovir Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Letrozole Abasia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Abdominal distension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Letrozole Abdominal pain 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Letrozole Abdominal pain lower 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Letrozole Abdominal tenderness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Abscess 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Acute coronary syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Acute generalised exanthematous pustulosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Letrozole Acute myeloid leukaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Letrozole Acute myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Acute respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Letrozole Agitation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Alanine aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Amnesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Anxiety 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Arrhythmia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Arrhythmia supraventricular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Letrozole Arthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Letrozole Arthropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Letrozole Aspartate aminotransferase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Atrial fibrillation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Letrozole Back pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Balance disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Blindness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Blood bilirubin increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Blood creatinine increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Blood glucose increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Blood lactate dehydrogenase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Blood pressure increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Bone pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Letrozole Brain injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole C-reactive protein increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Letrozole Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Cardiac disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Cardiac failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Cardiac murmur 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Cardiomyopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Letrozole Cardiovascular disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Carpal tunnel syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Cataract 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Letrozole Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Cerebral haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Cerebrovascular accident 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Chest discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Chromaturia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Colitis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Letrozole Colitis ischaemic 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Letrozole Confusional state 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Cough 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Letrozole Deep vein thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Dementia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Depressed mood 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Letrozole Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Dermatitis allergic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Dermatitis bullous 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Diabetes mellitus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Diarrhoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Letrozole Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Disease recurrence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Disorientation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Letrozole Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Letrozole Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Drug eruption 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Drug resistance 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Letrozole Drug-induced liver injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Dry eye 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Letrozole Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Dry skin 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Letrozole Dysaesthesia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Letrozole Dysgeusia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Dyspepsia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Dysphagia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Dyspnoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Letrozole Eating disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Eczema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Ejection fraction decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Electrocardiogram QT prolonged 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Epistaxis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Erythema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Erythema multiforme 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Letrozole Febrile neutropenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Letrozole Feeling abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Fluid retention 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Letrozole Flushing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Letrozole Gamma-glutamyltransferase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Haematoma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Haemoptysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Hemiparesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Hepatic enzyme increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Hepatic function abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Hepatic steatosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Hepatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Hepatocellular injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Hepatotoxicity 1.0 1.0 0.0 0.0 0.0 0.0 1.0 Letrozole Herpes zoster 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Hot flush 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Letrozole Hydronephrosis 0.0 0.0 1.0 0.0 1.0 0.0 0.0 Letrozole Hypercalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Hyperglycaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Letrozole Hyperhidrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Letrozole Hypertension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Letrozole Hypertensive crisis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Hyperthyroidism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Hypoaesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Hypokalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Hypotension 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Letrozole Ill-defined disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Letrozole Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Letrozole Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Intestinal perforation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Irritability 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Letrozole Ischaemic stroke 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Letrozole Jaundice 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Jaundice cholestatic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Joint stiffness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Letrozole Laryngeal oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Letrozole Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Letrozole Limb discomfort 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Letrozole Liver function test increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Lower respiratory tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Letrozole Lymphadenopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Lymphoedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Malnutrition 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Mass 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Memory impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Metastases to central nervous system 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Letrozole Metastases to liver 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Metastases to lung 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Migraine 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Mobility decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Letrozole Mouth ulceration 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Mucosal inflammation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Muscle atrophy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Letrozole Muscle rigidity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Muscle spasms 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Muscle tightness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Letrozole Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Letrozole Musculoskeletal chest pain 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Musculoskeletal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Letrozole Musculoskeletal stiffness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Letrozole Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Letrozole Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Nail disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Letrozole Nasopharyngitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Neoplasm 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Letrozole Neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Nervous system disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Neuralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Letrozole Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Letrozole Neutrophil count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Oral discomfort 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Letrozole Osteoarthritis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Osteoporosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Letrozole Palpitations 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Letrozole Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Pancytopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Letrozole Paraesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Peritonitis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Letrozole Platelet count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Letrozole Pleural effusion 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Letrozole Pneumonitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Pneumothorax 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Polyneuropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Letrozole Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Letrozole Pulmonary congestion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Pulmonary embolism 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Letrozole Pulmonary fibrosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Pulmonary mass 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Purpura 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Letrozole Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Rash erythematous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Rash maculo-papular 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Rectal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Letrozole Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Respiratory disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Retinal haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Rheumatoid arthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Sepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Letrozole Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Sleep disorder 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Letrozole Small intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Spinal compression fracture 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Subarachnoid haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Suicidal ideation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Letrozole Swelling face 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Letrozole Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Tendonitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Letrozole Tension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Letrozole Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Letrozole Thrombophlebitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Tinnitus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Letrozole Toxic epidermal necrolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Toxic skin eruption 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Transaminases increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Treatment failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Letrozole Urinary tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Vaginal haemorrhage 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Letrozole Venous thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Letrozole Vertigo 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole Viral infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Letrozole Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Letrozole Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Letrozole Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Letrozole Weight decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Letrozole Weight increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Letrozole White blood cell count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leucovorin Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leucovorin Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leucovorin Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leucovorin Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Leucovorin Alanine aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leucovorin Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leucovorin Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Leucovorin Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Leucovorin Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leucovorin Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leucovorin Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leucovorin Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leucovorin Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leucovorin Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leucovorin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Leucovorin Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leucovorin Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leucovorin Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Leucovorin Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leucovorin Febrile neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leucovorin Flatulence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leucovorin Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leucovorin Haematemesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leucovorin Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leucovorin Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Leucovorin Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leucovorin Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Leucovorin Hypotonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Leucovorin Ileus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leucovorin Interstitial lung disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leucovorin Intestinal perforation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leucovorin Lymphocyte count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leucovorin Malignant neoplasm progression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Leucovorin Mucosal inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leucovorin Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Leucovorin Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leucovorin Neoplasm progression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leucovorin Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leucovorin Neurotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leucovorin Neutropenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leucovorin Oropharyngeal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leucovorin Pain 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Leucovorin Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Leucovorin Pulmonary embolism 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Leucovorin Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leucovorin Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leucovorin Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Leucovorin Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Leucovorin Tachycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Leucovorin Thrombocytopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leucovorin Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leucovorin Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leucovorin calcium Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leucovorin calcium Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leucovorin calcium Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Leucovorin calcium Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leucovorin calcium Thrombocytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Leucovorin calcium Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Abdominal distension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Acute coronary syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Angina pectoris 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Arrhythmia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Arthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Arthropathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Asthenia 1.0 0.0 1.0 1.0 0.0 0.0 0.0 Leuprolide acetate Blood creatinine increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Leuprolide acetate Bone pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Breast pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leuprolide acetate Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leuprolide acetate Cardiac failure congestive 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Cerebrovascular accident 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Chills 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Circulatory collapse 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Connective tissue disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Cough 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Crying 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Leuprolide acetate Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leuprolide acetate Discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Dysmenorrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leuprolide acetate Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Dysphagia 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leuprolide acetate Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leuprolide acetate Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Flatulence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leuprolide acetate Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Gastrointestinal haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Gynaecomastia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leuprolide acetate Haematuria 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Haemoptysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Hepatic function abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Hepatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Hot flush 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leuprolide acetate Hyperhidrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Hypoacusis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leuprolide acetate Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Hypotension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Injury 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Irritability 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leuprolide acetate Libido decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Loss of libido 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leuprolide acetate Malaise 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Malnutrition 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Mood swings 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Muscle atrophy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leuprolide acetate Musculoskeletal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Musculoskeletal stiffness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Leuprolide acetate Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Nervous system disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Nervousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leuprolide acetate Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leuprolide acetate Night sweats 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Leuprolide acetate Nodule 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leuprolide acetate Osteoarthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Palpitations 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Paralysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Leuprolide acetate Phlebitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Pollakiuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Prostate cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Leuprolide acetate Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Pulmonary embolism 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Pulmonary fibrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Leuprolide acetate Rash 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Red blood cell count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leuprolide acetate Skin cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leuprolide acetate Skin disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Sleep disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Somnolence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Suicidal ideation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Transient ischaemic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Urinary incontinence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Urinary tract disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Urinary tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Leuprolide acetate Vaginal haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Leuprolide acetate Vertigo 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Leuprolide acetate Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Leuprolide acetate Vomiting 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Leuprolide acetate Weight decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Leuprolide acetate Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Levetiracetam Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Abdominal pain upper 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Levetiracetam Abnormal dreams 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Acidosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Acne 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Acute generalised exanthematous pustulosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Acute hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Acute kidney injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Acute respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Aggression 0.0 0.0 0.0 0.0 1.0 0.0 1.0 Levetiracetam Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Agranulocytosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Alanine aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Altered state of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Amnesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Anal incontinence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Anaphylactic reaction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Anger 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Angioedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Levetiracetam Apathy 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Levetiracetam Aphasia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Levetiracetam Aplastic anaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Apnoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Arrhythmia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Arthralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Arthropathy 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Levetiracetam Ascites 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Asthma 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levetiracetam Ataxia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Atrial septal defect 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Levetiracetam Atrioventricular block first degree 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Atrioventricular block second degree 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Balance disorder 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Levetiracetam Blood albumin decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Blood creatine phosphokinase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Blood creatinine increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Blood lactate dehydrogenase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Bone pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Bradyphrenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Brain oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Bronchitis 0.0 0.0 1.0 0.0 1.0 0.0 0.0 Levetiracetam C-reactive protein increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Cardiopulmonary failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Cardiotoxicity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Cerebral infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Chills 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levetiracetam Cholecystitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Chronic kidney disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Circulatory collapse 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Cognitive disorder 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Levetiracetam Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Confusional state 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Conjunctivitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Constipation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Coordination abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levetiracetam Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Cyanosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Deep vein thrombosis 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Levetiracetam Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Delusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Depressed level of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Depressed mood 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levetiracetam Depression 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Dermatitis bullous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Diplopia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levetiracetam Discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Disease progression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Disease recurrence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Disturbance in attention 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Levetiracetam Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Drug eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Drug hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Drug interaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Drug intolerance 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Levetiracetam Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Drug resistance 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Dysaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Dysarthria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Dyspepsia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Ear disorder 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Levetiracetam Ear infection 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Levetiracetam Ear pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Emotional disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Eosinophilia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levetiracetam Epilepsy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Epistaxis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Erythema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Extrasystoles 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Eye pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Levetiracetam Febrile neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Feeling abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Feeling jittery 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Flushing 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Foetal death 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Levetiracetam Foetal growth restriction 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Levetiracetam Gait disturbance 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levetiracetam Gamma-glutamyltransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Generalised tonic-clonic seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Glycosuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Granulocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Haematemesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Haematocrit decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Haemoglobin decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Hallucination, visual 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Hepatic encephalopathy 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Hepatic function abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Hepatic steatosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Hepatitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Hepatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Hepatocellular injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Hepatotoxicity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Hyperkalaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Hypernatraemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Hypersensitivity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levetiracetam Hyperthyroidism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Hypertonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levetiracetam Hypoalbuminaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Hypocalcaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Hypomagnesaemia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Levetiracetam Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Hyporeflexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Hypothermia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Hypotonia 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Levetiracetam Hypoxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Inappropriate antidiuretic hormone secretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Influenza like illness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Levetiracetam Intentional self-injury 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levetiracetam Interstitial lung disease 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Irritability 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Jaundice 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Keratitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Lactic acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Laryngitis 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Levetiracetam Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Libido decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Liver function test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Liver injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Lower respiratory tract infection 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levetiracetam Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Lymphadenopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Lymphocyte count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Malaise 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Levetiracetam Malignant neoplasm progression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Mania 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Maternal drugs affecting foetus 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Levetiracetam Medication residue present 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Melaena 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Mental disorder 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Levetiracetam Mental impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Mental status changes 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Metabolic acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Metabolic disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Metastases to central nervous system 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Micturition urgency 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Migraine 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Mobility decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Mood altered 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Levetiracetam Mood swings 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Motor dysfunction 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Levetiracetam Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Muscle twitching 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Levetiracetam Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Myoclonus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Nasopharyngitis 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Levetiracetam Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Neoplasm 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Nervous system disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levetiracetam Nervousness 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Levetiracetam Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Neurotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Nystagmus 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Levetiracetam Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Oropharyngeal discomfort 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Levetiracetam Osteoporosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levetiracetam Oxygen saturation decreased 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Levetiracetam Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Pallor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Pancreatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Pancytopenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Panic attack 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levetiracetam Paralysis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levetiracetam Parosmia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Pericardial effusion 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Levetiracetam Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Peritonitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Personality change 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levetiracetam Personality disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Photophobia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levetiracetam Photosensitivity reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Pleural effusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Pollakiuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Poor quality sleep 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levetiracetam Posterior reversible encephalopathy syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Pregnancy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 1.0 Levetiracetam Premature delivery 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Presyncope 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Levetiracetam Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levetiracetam Pseudomembranous colitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Psoriasis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Psychomotor hyperactivity 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Levetiracetam Psychotic disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Rash generalised 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Rash maculo-papular 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Rash papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Rash pruritic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Rash pustular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Red blood cell count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Renal tubular necrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Respiratory depression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Respiratory disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Respiratory distress 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Levetiracetam Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Salivary hypersecretion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Serotonin syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Sinus bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Sinus tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Skin discolouration 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Skin ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Sleep apnoea syndrome 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Levetiracetam Sleep disorder 0.0 0.0 0.0 0.0 1.0 0.0 1.0 Levetiracetam Sopor 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Speech disorder 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Levetiracetam Splenomegaly 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Status epilepticus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Stevens-Johnson syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Stomatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Stress 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Stress cardiomyopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Subarachnoid haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Subdural haematoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Syncope 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Levetiracetam Systemic lupus erythematosus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Tachycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Tension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levetiracetam Thinking abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Thrombocytopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Thrombocytopenic purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Toothache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Torsade de pointes 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Toxic epidermal necrolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Toxic skin eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Transaminases increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Treatment failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Tremor 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Levetiracetam Tubulointerstitial nephritis 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Unevaluable event 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Levetiracetam Unresponsive to stimuli 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Upper gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Upper respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levetiracetam Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Ventricular fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Visual acuity reduced 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam Visual impairment 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Levetiracetam Vomiting 0.0 0.0 1.0 0.0 1.0 0.0 0.0 Levetiracetam Weight decreased 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Levetiracetam Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levetiracetam White blood cell count increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levetiracetam Withdrawal syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levocetirizine Arrhythmia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levocetirizine Drug eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levocetirizine Drug-induced liver injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levocetirizine Dyspnoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levocetirizine Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levocetirizine Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levocetirizine Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levocetirizine Pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levocetirizine Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levocetirizine Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levocetirizine dihydrochloride Angioedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levocetirizine dihydrochloride Asthenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levocetirizine dihydrochloride Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levocetirizine dihydrochloride Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levocetirizine dihydrochloride Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levocetirizine dihydrochloride Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levocetirizine dihydrochloride Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levocetirizine dihydrochloride Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levocetirizine dihydrochloride Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levocetirizine dihydrochloride Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levocetirizine dihydrochloride Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Levocetirizine dihydrochloride Pyrexia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levocetirizine dihydrochloride Somnolence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levocetirizine dihydrochloride Suicidal ideation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levocetirizine dihydrochloride Urinary retention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levocetirizine dihydrochloride Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levodopa Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levodopa Asthenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Levodopa Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levodopa Choking 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levodopa Cough 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Levodopa Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levodopa Dementia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levodopa Dysgeusia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levodopa Dyskinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levodopa Dyspnoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levodopa Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levodopa Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levodopa Hypotension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levodopa Panic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levodopa Parkinson's disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levodopa Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Levodopa Pneumonia aspiration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levodopa Sepsis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levodopa Throat irritation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Abasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Abdominal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Abdominal distension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Abdominal pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Abdominal pain lower 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Abdominal pain upper 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Abnormal dreams 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Abnormal faeces 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levofloxacin Abscess 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Acute generalised exanthematous pustulosis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Acute hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Acute myeloid leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Acute myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Acute respiratory distress syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Acute respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Ageusia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Aggression 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Agitation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Agranulocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Altered state of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Amnesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Anaemia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Levofloxacin Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Levofloxacin Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Anger 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Angina pectoris 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Angioedema 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Levofloxacin Anuria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Anxiety 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Levofloxacin Apathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Aphasia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Arrhythmia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Arthralgia 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Levofloxacin Arthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Arthropathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Ascites 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Aspartate aminotransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Asthenia 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Levofloxacin Atelectasis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Atrial fibrillation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Atrioventricular block 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Back pain 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Levofloxacin Bacteraemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Balance disorder 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Levofloxacin Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Blister 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Blood alkaline phosphatase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Blood bilirubin increased 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Blood creatinine increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Blood lactate dehydrogenase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Blood potassium decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Blood pressure abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Blood pressure decreased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Blood pressure increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Blood urea increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Bone marrow failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Bone pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Bradycardia 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Bronchitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Burning sensation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Bursitis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin C-reactive protein increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Candida infection 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Cardiac disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Cardiovascular disorder 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Levofloxacin Carpal tunnel syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Cerebral haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Cerebrovascular accident 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Chest discomfort 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Chest pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Chills 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Choking 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Chromaturia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Chronic kidney disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Chronic obstructive pulmonary disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Circulatory collapse 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Clostridium difficile colitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Clostridium difficile infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Coagulopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Cognitive disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Cold sweat 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Confusional state 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Levofloxacin Connective tissue disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Contusion 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Cough 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Crying 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Deafness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Decreased appetite 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Deep vein thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Dehydration 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Levofloxacin Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Delusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Depersonalisation/derealisation disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Depressed level of consciousness 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Levofloxacin Depressed mood 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Dermatitis bullous 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Diarrhoea 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Levofloxacin Diplopia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Discomfort 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Disorientation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Disseminated intravascular coagulation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Disturbance in attention 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Dizziness 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Levofloxacin Drug hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Drug interaction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Drug intolerance 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Levofloxacin Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Drug resistance 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Drug-induced liver injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Dry eye 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Dry skin 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Dysaesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levofloxacin Dysarthria 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Levofloxacin Dysgeusia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Dyskinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Dyspepsia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Dysphagia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Dysphonia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Dyspnoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Dysstasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Eczema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Electrolyte imbalance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Emotional distress 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Encephalopathy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Enterocolitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Eosinophilia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Epilepsy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Erythema 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Erythema multiforme 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Extrasystoles 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Eye disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Eye irritation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Eye pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Fatigue 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Levofloxacin Fear 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Feeling abnormal 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Levofloxacin Feeling cold 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Feeling hot 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Feeling jittery 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levofloxacin Flatulence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Flushing 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Fungal infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Gait disturbance 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Levofloxacin Gamma-glutamyltransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Gastric disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Gastritis 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Gastrointestinal disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Gastrooesophageal reflux disease 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Generalised tonic-clonic seizure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Gingival bleeding 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Haematoma 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Haemodynamic instability 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Haemolytic anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Haemoptysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Haemorrhage 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Haemorrhoids 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Hallucination 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Hallucination, auditory 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Headache 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Levofloxacin Heart rate decreased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Heart rate increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Heart rate irregular 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Hemiparesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Hemiplegia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Hepatic enzyme increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Hepatic function abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Hepatic necrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Hepatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Hepatotoxicity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Hot flush 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Hyperaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Hyperbilirubinaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Hyperkalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Hyperpyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Hypersensitivity vasculitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Hypertension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Hypertriglyceridaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Hypoacusis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Levofloxacin Hypoaesthesia 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Levofloxacin Hypoaesthesia oral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Hypoglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Hypokalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Hypokinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Hypomagnesaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Hyponatraemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Immune system disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Immune thrombocytopenic purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Inappropriate antidiuretic hormone secretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Induration 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levofloxacin Infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Inflammation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Influenza like illness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Insomnia 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Levofloxacin Intervertebral disc protrusion 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Irritability 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Jaundice 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Joint stiffness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Joint swelling 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Levofloxacin Lacrimation increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Laryngeal oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Left ventricular dysfunction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Lethargy 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Leukocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Leukopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Limb discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Lip swelling 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Liver disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Liver function test abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Loss of consciousness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Lung disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Lymphadenopathy 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Malaise 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Malnutrition 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Melaena 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Memory impairment 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Mental disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Metabolic disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Middle insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Migraine 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Mobility decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Mood altered 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Motor dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Mouth ulceration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Movement disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Muscle atrophy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Muscle contractions involuntary 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Muscle rigidity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Muscle tightness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Muscle twitching 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Muscular weakness 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Levofloxacin Musculoskeletal chest pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levofloxacin Musculoskeletal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Musculoskeletal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Musculoskeletal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Musculoskeletal stiffness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Myalgia 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Levofloxacin Myocardial infarction 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Myoclonus 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Levofloxacin Myopathy 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Myositis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levofloxacin Nasopharyngitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Nausea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Neck pain 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Levofloxacin Nervous system disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Nervousness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Neuralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Neuritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levofloxacin Neurotoxicity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Night sweats 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Nightmare 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Nodule 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Oedema 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Oedema peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Oral pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Oropharyngeal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Orthostatic hypotension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Osteoarthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Oxygen saturation decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Pain 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Levofloxacin Pain in extremity 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Levofloxacin Pallor 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Palpitations 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Levofloxacin Pancreatitis acute 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Pancytopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Panic attack 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Paraesthesia 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Levofloxacin Paraesthesia oral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levofloxacin Paralysis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Paranoia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Parosmia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Pelvic pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Peripheral coldness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Peripheral sensory neuropathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Petechiae 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Pharyngeal oedema 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Photophobia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Photosensitivity reaction 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Platelet count decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Pleural effusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Pleurisy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Pneumonia 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Pneumonitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Pneumothorax 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Polyneuropathy 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Presyncope 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Pseudomembranous colitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Psychomotor hyperactivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Psychotic disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Pulmonary embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Pyrexia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Levofloxacin Rash 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Levofloxacin Rash erythematous 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Rash generalised 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Rash papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Rash pruritic 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Rash pustular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Renal impairment 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Renal tubular necrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Respiratory depression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Respiratory disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Respiratory distress 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Respiratory tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Restlessness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Retching 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levofloxacin Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Rhinitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Salivary hypersecretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Seizure 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Sensory disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Sensory loss 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Sepsis 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Sinusitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Skin burning sensation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Skin discolouration 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Skin disorder 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Levofloxacin Skin exfoliation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Skin hyperpigmentation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levofloxacin Skin lesion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Skin ulcer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Sleep disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Somnolence 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Sopor 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Speech disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Staphylococcal infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Status epilepticus 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Stevens-Johnson syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Stomatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Stress 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Subdural haematoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Suicidal ideation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Swelling face 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Swollen tongue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Syncope 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Systemic lupus erythematosus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Tachycardia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Tachypnoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Tenderness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Tendon rupture 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Levofloxacin Tendonitis 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Levofloxacin Thinking abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Thrombocytopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Thrombosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Tinnitus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Tongue oedema 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Tooth disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Torsade de pointes 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Toxic epidermal necrolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Transaminases increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Treatment failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levofloxacin Tremor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Unevaluable event 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Unresponsive to stimuli 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Upper gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Urinary incontinence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Urinary retention 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Urinary tract disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Urinary tract infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Urticaria 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Levofloxacin Vaginal haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levofloxacin Vascular purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin Ventricular fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Ventricular tachycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin Vertigo 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Vision blurred 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Levofloxacin Visual acuity reduced 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Visual impairment 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Levofloxacin Vomiting 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Levofloxacin Weight decreased 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Levofloxacin Weight increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levofloxacin Wheezing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levofloxacin White blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levofloxacin White blood cell count increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levomilnacipran hydrochloride Hyperhidrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levomilnacipran hydrochloride Serotonin syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levomilnacipran hydrochloride Suicidal ideation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Abasia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Abdominal distension 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Abdominal pain 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Levonorgestrel Abdominal pain lower 0.0 1.0 0.0 0.0 0.0 1.0 1.0 Levonorgestrel Abdominal pain upper 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Levonorgestrel Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 1.0 1.0 Levonorgestrel Abscess 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levonorgestrel Acne 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Acute kidney injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levonorgestrel Affect lability 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Aggression 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Levonorgestrel Alopecia 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Amenorrhoea 0.0 0.0 0.0 0.0 0.0 1.0 1.0 Levonorgestrel Amnesia 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Anaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levonorgestrel Anger 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Angina pectoris 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levonorgestrel Anxiety 0.0 1.0 1.0 1.0 0.0 1.0 0.0 Levonorgestrel Apathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Aphasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Appendicitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levonorgestrel Arrhythmia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Arthralgia 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Arthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Arthropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Asthenia 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Asthma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Back pain 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Balance disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Blindness 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Blood cholesterol increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Blood pressure increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Bone pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Breast cancer 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Breast enlargement 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Breast pain 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Bronchitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Burning sensation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Candida infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Cerebrovascular accident 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Chest discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Chest pain 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Levonorgestrel Chills 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Cognitive disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Cold sweat 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Colitis ulcerative 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levonorgestrel Confusional state 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Levonorgestrel Constipation 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Levonorgestrel Contusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levonorgestrel Cough 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Crying 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Cyst 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Cystitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Deafness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levonorgestrel Decreased appetite 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Levonorgestrel Deep vein thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levonorgestrel Depressed level of consciousness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Depressed mood 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Levonorgestrel Depression 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Levonorgestrel Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Diplopia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Discomfort 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Levonorgestrel Disturbance in attention 0.0 1.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Dizziness 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Drug hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Dry eye 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Levonorgestrel Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Dry skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levonorgestrel Dysgeusia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Dysmenorrhoea 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Dysphagia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Dyspnoea 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Levonorgestrel Dysuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levonorgestrel Eating disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Eczema 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Emotional disorder 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Levonorgestrel Emotional distress 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Levonorgestrel Epistaxis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Erythema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Eye pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Fatigue 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Fear 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levonorgestrel Feeling abnormal 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Feeling jittery 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Flank pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levonorgestrel Flatulence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Fluid retention 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Foetal death 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levonorgestrel Fungal infection 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Gait disturbance 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Levonorgestrel Galactorrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Gamma-glutamyltransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Gastrointestinal disorder 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Levonorgestrel Gastrooesophageal reflux disease 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Generalised tonic-clonic seizure 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Haematochezia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Haematuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Haemorrhage 0.0 1.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Haemorrhoids 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Hallucination 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Headache 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Heart rate increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Hemiplegia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levonorgestrel Hirsutism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Hot flush 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Hyperhidrosis 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Hypersomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Hypertension 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Levonorgestrel Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levonorgestrel Hypothyroidism 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Immune system disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Increased appetite 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Infection 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Levonorgestrel Inflammation 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Levonorgestrel Influenza 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Insomnia 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Intervertebral disc protrusion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Intestinal perforation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levonorgestrel Intracranial pressure increased 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Intraocular pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Iron deficiency anaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Irritability 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Irritable bowel syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Joint swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Lethargy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Libido decreased 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Limb discomfort 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Levonorgestrel Loss of consciousness 0.0 0.0 0.0 0.0 0.0 1.0 1.0 Levonorgestrel Loss of libido 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Lung disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levonorgestrel Lymphadenopathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Malaise 0.0 1.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Memory impairment 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Menopausal symptoms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Menorrhagia 0.0 1.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Menstrual disorder 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Menstruation irregular 0.0 0.0 0.0 0.0 0.0 1.0 1.0 Levonorgestrel Mental disorder 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Levonorgestrel Mental impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Metrorrhagia 0.0 0.0 0.0 0.0 0.0 1.0 1.0 Levonorgestrel Micturition urgency 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Migraine 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Mobility decreased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Mood altered 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Levonorgestrel Mood swings 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Muscle spasms 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Levonorgestrel Muscle twitching 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Musculoskeletal disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Musculoskeletal pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Levonorgestrel Musculoskeletal stiffness 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Levonorgestrel Myalgia 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levonorgestrel Nasopharyngitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Nausea 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Neck pain 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Nervous system disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Nervousness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Levonorgestrel Neuralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Night sweats 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Oedema peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Optic neuritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Oropharyngeal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Osteoarthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Pain 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Levonorgestrel Pain in extremity 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Pallor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Palpitations 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Levonorgestrel Panic attack 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Levonorgestrel Paraesthesia 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Pelvic pain 0.0 1.0 0.0 0.0 0.0 1.0 1.0 Levonorgestrel Peripheral swelling 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Levonorgestrel Peritonitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levonorgestrel Pharyngeal oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Photophobia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Levonorgestrel Pigmentation disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Pollakiuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Pregnancy 0.0 1.0 0.0 0.0 0.0 1.0 1.0 Levonorgestrel Premature baby 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Levonorgestrel Premature delivery 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levonorgestrel Presyncope 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Pruritus 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Pruritus generalised 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Psoriasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Pulmonary embolism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levonorgestrel Pyrexia 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Levonorgestrel Rash 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Levonorgestrel Rash macular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Rash pruritic 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Rectal haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Renal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Respiratory failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levonorgestrel Restless legs syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Restlessness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Rheumatoid arthritis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Levonorgestrel Sciatica 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Seizure 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Sepsis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levonorgestrel Septic shock 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Levonorgestrel Sexual dysfunction 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Levonorgestrel Shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levonorgestrel Shock haemorrhagic 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levonorgestrel Sinusitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Skin discolouration 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Skin disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Skin exfoliation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Skin lesion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Skin odour abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Sleep disorder 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Levonorgestrel Somnolence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Speech disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Stress 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levonorgestrel Suicidal ideation 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Levonorgestrel Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levonorgestrel Swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Swelling face 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Levonorgestrel Syncope 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Systemic lupus erythematosus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Tachycardia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Levonorgestrel Tendonitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Thrombosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Tinnitus 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Tooth disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Tremor 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Levonorgestrel Unevaluable event 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Levonorgestrel Urinary incontinence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levonorgestrel Urinary tract disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Urinary tract infection 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Urticaria 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Levonorgestrel Vaginal discharge 0.0 0.0 0.0 0.0 0.0 1.0 1.0 Levonorgestrel Vaginal haemorrhage 0.0 0.0 0.0 0.0 0.0 1.0 1.0 Levonorgestrel Vaginal infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Vertigo 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Vision blurred 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Visual acuity reduced 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Visual field defect 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Visual impairment 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Vomiting 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Vulvovaginal candidiasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Vulvovaginal mycotic infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levonorgestrel Weight decreased 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levonorgestrel Weight increased 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Levothyroxine Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levothyroxine Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levothyroxine Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levothyroxine Anger 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Levothyroxine Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levothyroxine Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levothyroxine Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levothyroxine Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levothyroxine Balance disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine Burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levothyroxine Cardiac failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levothyroxine Cardiogenic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levothyroxine Cerebrovascular accident 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine Chest pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levothyroxine Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levothyroxine Crying 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levothyroxine Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levothyroxine Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levothyroxine Depression 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Levothyroxine Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levothyroxine Discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levothyroxine Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine Dysarthria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levothyroxine Dysphagia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levothyroxine Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Levothyroxine Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Levothyroxine Feeling cold 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levothyroxine Gastrointestinal disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine Headache 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Levothyroxine Hepatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levothyroxine Hip fracture 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine Hot flush 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levothyroxine Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine Hyperthyroidism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levothyroxine Hypoaesthesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levothyroxine Hypothyroidism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levothyroxine Intracranial pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine Ischaemic stroke 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levothyroxine Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levothyroxine Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levothyroxine Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levothyroxine Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levothyroxine Mood swings 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levothyroxine Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levothyroxine Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levothyroxine Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levothyroxine Nervousness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levothyroxine Pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levothyroxine Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levothyroxine Palpitations 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levothyroxine Pancytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levothyroxine Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levothyroxine Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Levothyroxine Pneumonia aspiration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levothyroxine Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Levothyroxine Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Levothyroxine Rash 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Levothyroxine Respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levothyroxine Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Levothyroxine Sleep disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levothyroxine Suicidal ideation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levothyroxine Tinnitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine Treatment failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Levothyroxine Vertigo 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Levothyroxine sodium Abdominal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine sodium Affect lability 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine sodium Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine sodium Angina pectoris 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine sodium Angioedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine sodium Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine sodium Arrhythmia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine sodium Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Levothyroxine sodium Blood pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine sodium Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Levothyroxine sodium Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levothyroxine sodium Diarrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine sodium Dyspnoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine sodium Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine sodium Gastrointestinal disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine sodium Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine sodium Heart rate increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine sodium Hyperhidrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine sodium Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine sodium Hyperthyroidism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine sodium Increased appetite 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine sodium Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine sodium Irritability 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine sodium Menstruation irregular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine sodium Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Levothyroxine sodium Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Levothyroxine sodium Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine sodium Nervousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine sodium Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine sodium Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine sodium Psychomotor hyperactivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine sodium Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine sodium Tachycardia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine sodium Tremor 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine sodium Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine sodium Vomiting 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Levothyroxine sodium Weight decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lidocaine Agitation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lidocaine Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lidocaine Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lidocaine Apnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lidocaine Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lidocaine Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lidocaine Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lidocaine Cardiac disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lidocaine Circulatory collapse 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lidocaine Coma 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lidocaine Confusional state 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lidocaine Constipation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lidocaine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lidocaine Depressed level of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lidocaine Diplopia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lidocaine Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lidocaine Dysarthria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lidocaine Dysphagia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lidocaine Dysphonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lidocaine Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lidocaine Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lidocaine Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lidocaine Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lidocaine Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lidocaine Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lidocaine Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lidocaine Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lidocaine Nausea 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Lidocaine Neurotoxicity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lidocaine Paraesthesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lidocaine Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lidocaine Respiratory depression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lidocaine Seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lidocaine Shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lidocaine Tremor 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lidocaine Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lidocaine Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lidocaine Ventricular fibrillation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lidocaine Ventricular tachycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lidocaine Vision blurred 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lidocaine Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lidocaine hydrochloride Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lidocaine hydrochloride Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lidocaine hydrochloride Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lidocaine hydrochloride Circulatory collapse 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lidocaine hydrochloride Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lidocaine hydrochloride Hypoaesthesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lidocaine hydrochloride Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lidocaine hydrochloride Loss of consciousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lidocaine hydrochloride Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lidocaine hydrochloride Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lidocaine hydrochloride Respiratory failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lidocaine hydrochloride Seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lifitegrast Blindness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lifitegrast Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lifitegrast Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lifitegrast Dry eye 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lifitegrast Dysgeusia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Lifitegrast Eye disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lifitegrast Eye haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lifitegrast Eye irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lifitegrast Eye pain 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Lifitegrast Eye pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lifitegrast Eye swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lifitegrast Feeling abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lifitegrast Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lifitegrast Headache 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Lifitegrast Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lifitegrast Lacrimation increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lifitegrast Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lifitegrast Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lifitegrast Ocular hyperaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lifitegrast Photophobia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lifitegrast Sinusitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lifitegrast Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lifitegrast Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Linaclotide Abdominal distension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Linaclotide Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linaclotide Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linaclotide Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linaclotide Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Linaclotide Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Linaclotide Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linaclotide Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Linaclotide Diverticulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linaclotide Flatulence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Linaclotide Haematochezia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Linaclotide Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Linaclotide Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linaclotide Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Linaclotide Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linaclotide Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linaclotide Rectal haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Linaclotide Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linaclotide Weight decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Linaclotide Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Linagliptin Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Abdominal pain upper 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Alanine aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Angina pectoris 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Angioedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Linagliptin Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Linagliptin Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Blood glucose decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Blood pressure decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Blood urea increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Linagliptin Cardiac failure congestive 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Cerebrovascular accident 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Linagliptin Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Chronic kidney disease 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Linagliptin Constipation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Linagliptin Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Depression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Dermatitis bullous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Linagliptin Diabetes mellitus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Linagliptin Drug eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Dyspnoea 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Linagliptin Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Fluid retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Linagliptin Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Linagliptin Hyperglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Hyperkalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Hypoglycaemia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Linagliptin Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Lipase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Linagliptin Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Linagliptin Pancreatic carcinoma 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Linagliptin Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Pancreatitis acute 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Paraesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Linagliptin Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Linagliptin Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linagliptin Renal failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Renal impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Sepsis 1.0 0.0 1.0 1.0 0.0 0.0 0.0 Linagliptin Skin ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Unevaluable event 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linagliptin Weight decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Linezolid Acute generalised exanthematous pustulosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Linezolid Acute hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Linezolid Acute respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linezolid Agranulocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Alopecia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linezolid Altered state of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Anaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Angioedema 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Linezolid Anuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Aplastic anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linezolid Asthenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Linezolid Atrial fibrillation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Linezolid Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linezolid Bacteraemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Linezolid Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Linezolid Blood creatine phosphokinase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Linezolid Blood creatinine increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Blood disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Linezolid Blood pressure decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Body temperature increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Linezolid Bone marrow failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Candida infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Cardiopulmonary failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Linezolid Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Chills 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linezolid Clostridium difficile colitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Clostridium difficile infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Coagulopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Linezolid Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linezolid Cough 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Linezolid Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Linezolid Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linezolid Delirium 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Linezolid Depressed level of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linezolid Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Linezolid Disorientation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Linezolid Disseminated intravascular coagulation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Linezolid Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linezolid Drug eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linezolid Drug hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Drug interaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Linezolid Drug resistance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Linezolid Drug-induced liver injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Dysgeusia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Linezolid Dysphagia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Linezolid Dyspnoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Encephalopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Eosinophilia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Linezolid Epilepsy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Epistaxis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linezolid Face oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linezolid Faeces discoloured 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linezolid Fluid retention 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Linezolid Full blood count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linezolid Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Linezolid Gastric ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linezolid Gastrointestinal disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Linezolid Generalised tonic-clonic seizure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Linezolid Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linezolid Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linezolid Hallucination 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Linezolid Heart rate increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Linezolid Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Hepatic function abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linezolid Hepatitis cholestatic 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Linezolid Hepatomegaly 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linezolid Hepatotoxicity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Hyperhidrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Linezolid Hyperkalaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linezolid Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Hyperthermia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Hypoacusis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Linezolid Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Linezolid Hypoglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Hypokalaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Linezolid Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Linezolid Jaundice cholestatic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linezolid Lactic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Lip swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linezolid Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Lymphopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Malaise 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Linezolid Melaena 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linezolid Metabolic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Mouth ulceration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linezolid Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Muscular weakness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Linezolid Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Linezolid Myoclonus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Nephrotic syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Linezolid Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Linezolid Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Neutrophil count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Oedema peripheral 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Linezolid Oxygen saturation decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Linezolid Pancytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Petechiae 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linezolid Platelet count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Pleural effusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Linezolid Polyneuropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Linezolid Posterior reversible encephalopathy syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linezolid Pulmonary embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linezolid Pyrexia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Linezolid Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linezolid Rash erythematous 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linezolid Rash generalised 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Linezolid Rash macular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linezolid Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Renal impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Respiratory distress 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Rhabdomyolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Serotonin syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Stevens-Johnson syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linezolid Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linezolid Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Linezolid Tachypnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Thrombocytopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Linezolid Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Linezolid Tongue discolouration 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Linezolid Transaminases increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Linezolid Treatment failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Linezolid Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linezolid Tubulointerstitial nephritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Linezolid Urinary tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Linezolid Urticaria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linezolid Vertigo 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Linezolid Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Linezolid Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Linezolid Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Linezolid White blood cell count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Liothyronine Drug abuse 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Liothyronine Hyperthyroidism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Liraglutide Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Liraglutide Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Liraglutide Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Liraglutide Anaphylactic reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Liraglutide Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Liraglutide Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Liraglutide Cholecystitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Liraglutide Cholestasis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Liraglutide Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Liraglutide Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Liraglutide Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Liraglutide Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Liraglutide Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Liraglutide Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Liraglutide Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Liraglutide Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Liraglutide Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Liraglutide Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Liraglutide Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Liraglutide Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Liraglutide Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Liraglutide Malnutrition 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Liraglutide Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Liraglutide Neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Liraglutide Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Liraglutide Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Liraglutide Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Liraglutide Renal failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Liraglutide Suicidal ideation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Liraglutide Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisdexamfetamine dimesylate Aggression 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Lisdexamfetamine dimesylate Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lisdexamfetamine dimesylate Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisdexamfetamine dimesylate Cardiac disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lisdexamfetamine dimesylate Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Lisdexamfetamine dimesylate Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lisdexamfetamine dimesylate Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Lisdexamfetamine dimesylate Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisdexamfetamine dimesylate Dyskinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisdexamfetamine dimesylate Dyspnoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisdexamfetamine dimesylate Euphoric mood 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lisdexamfetamine dimesylate Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Lisdexamfetamine dimesylate Headache 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Lisdexamfetamine dimesylate Heart rate increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisdexamfetamine dimesylate Hyperhidrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisdexamfetamine dimesylate Hypertension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisdexamfetamine dimesylate Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lisdexamfetamine dimesylate Irritability 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lisdexamfetamine dimesylate Mania 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lisdexamfetamine dimesylate Myocardial infarction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lisdexamfetamine dimesylate Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisdexamfetamine dimesylate Nervousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lisdexamfetamine dimesylate Palpitations 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisdexamfetamine dimesylate Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lisdexamfetamine dimesylate Seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lisdexamfetamine dimesylate Somnolence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lisdexamfetamine dimesylate Tachycardia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisdexamfetamine dimesylate Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lisdexamfetamine dimesylate Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisdexamfetamine dimesylate Weight decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lisdexamfetamine dimesylate Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lisinopril Abdominal distension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Abdominal pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Abdominal pain upper 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Acidosis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Acute hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Acute kidney injury 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Lisinopril Acute myocardial infarction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Acute respiratory distress syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Acute respiratory failure 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Lisinopril Ageusia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Agitation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Lisinopril Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Angioedema 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Lisinopril Angiopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Aphasia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Arthralgia 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Lisinopril Arthritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Ascites 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Aspiration 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Asthma 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Atelectasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Atrioventricular block 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Atrioventricular block first degree 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Azotaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Balance disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Blood creatine phosphokinase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Blood glucose increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Blood potassium increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Blood pressure decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Blood pressure increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Blood sodium decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Blood urea increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Brain injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lisinopril Bronchospasm 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Cardiac disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Cardiac failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 1.0 0.0 Lisinopril Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Chest discomfort 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Chest pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Choking 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Chromaturia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Chronic kidney disease 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Chronic obstructive pulmonary disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Circulatory collapse 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Cold sweat 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Colitis ischaemic 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Confusional state 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Contusion 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Coordination abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Coronary artery disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Cough 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Lisinopril Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Dehydration 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Lisinopril Delirium 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Depressed level of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Depressed mood 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lisinopril Depression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lisinopril Diabetic ketoacidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Diarrhoea 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Lisinopril Discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lisinopril Diverticulitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Dizziness 0.0 1.0 1.0 1.0 0.0 1.0 0.0 Lisinopril Dizziness postural 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Drug eruption 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Drug hypersensitivity 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Lisinopril Drug interaction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lisinopril Drug-induced liver injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Dry mouth 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Duodenal ulcer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Dysarthria 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Dysphagia 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Lisinopril Dysphonia 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Lisinopril Dyspnoea 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Lisinopril Encephalopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Epistaxis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Erectile dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Eructation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Eye swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Eyelid oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Face oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Feeling abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Flank pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Flatulence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Gastrointestinal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lisinopril Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lisinopril Haemoptysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Headache 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Lisinopril Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Hepatic steatosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Hepatocellular injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Hyperglycaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Hyperkalaemia 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Lisinopril Hypersensitivity 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Lisinopril Hypersomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lisinopril Hypertensive crisis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Hypomagnesaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Hypotension 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Lisinopril Hypovolaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Hypoxia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Ileus 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Inappropriate antidiuretic hormone secretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Intestinal perforation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Ischaemic stroke 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Joint swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Lactic acidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Laryngeal oedema 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Lisinopril Laryngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Laryngospasm 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Lethargy 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Leukocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Lip swelling 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Lisinopril Local swelling 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Loss of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Lower respiratory tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Lymphadenopathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lisinopril Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Metabolic acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Mobility decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Mood altered 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Mouth ulceration 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lisinopril Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Muscular weakness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Musculoskeletal discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Myocardial ischaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Nausea 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Lisinopril Nephrolithiasis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Nephropathy toxic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Nocturia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Obstructive airways disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Oedema 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Oedema peripheral 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Oliguria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Oropharyngeal pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Osteoarthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Oxygen saturation decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Pain in extremity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Palpitations 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Pancreatitis 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Lisinopril Pancreatitis acute 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Paraesthesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Peripheral swelling 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Lisinopril Pharyngeal oedema 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Lisinopril Pneumonia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Pneumothorax 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Productive cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Pruritus 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Lisinopril Psoriasis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Pulmonary embolism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Pulmonary oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Rash 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Lisinopril Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Rash papular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lisinopril Rash pruritic 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Raynaud's phenomenon 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lisinopril Rectal haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Renal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Renal failure 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Lisinopril Renal impairment 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Renal tubular necrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Respiratory depression 0.0 0.0 1.0 0.0 0.0 1.0 0.0 Lisinopril Respiratory distress 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Lisinopril Respiratory failure 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Lisinopril Restlessness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Retching 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Sinus tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Skin disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Skin exfoliation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lisinopril Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Speech disorder 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Lisinopril Subarachnoid haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Swelling 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Lisinopril Swelling face 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Lisinopril Swollen tongue 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Lisinopril Syncope 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Tachycardia 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Lisinopril Tenderness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Throat irritation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Throat tightness 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Lisinopril Tongue oedema 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Treatment failure 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Troponin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Unresponsive to stimuli 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Urinary tract infection 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Urticaria 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Lisinopril Ventricular fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Vertigo 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lisinopril Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lisinopril Weight increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lisinopril Wheezing 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Lithium Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lithium Ataxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium Confusional state 0.0 0.0 1.0 0.0 0.0 1.0 0.0 Lithium Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium Dysarthria 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lithium Electrocardiogram abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium Restlessness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium Tremor 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Lithium Urinary incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Agitation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Aphasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Ataxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Balance disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Blood urea increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lithium carbonate Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lithium carbonate Cardiogenic shock 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Chronic kidney disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lithium carbonate Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lithium carbonate Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lithium carbonate Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lithium carbonate Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Depressed level of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Depressed mood 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Disturbance in attention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Drug abuse 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Drug reaction with eosinophilia and systemic symptoms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Dysarthria 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Dyskinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Electrocardiogram QT prolonged 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Encephalopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Headache 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lithium carbonate Hypercalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Hypernatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Hyperreflexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Hyperthermia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Hyperthyroidism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Hyporeflexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Hypotonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Intentional self-injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Irritability 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Leukocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Mania 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Maternal drugs affecting foetus 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Lithium carbonate Memory impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Metabolic acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Muscle contractions involuntary 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Muscle rigidity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lithium carbonate Muscle twitching 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Myoclonus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Nephropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lithium carbonate Posterior reversible encephalopathy syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Psychomotor hyperactivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Renal failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lithium carbonate Respiratory failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Restlessness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Salivary hypersecretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Sepsis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Sopor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Speech disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Status epilepticus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lithium carbonate Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lithium carbonate Weight decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lomitapide mesylate Abdominal distension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lomitapide mesylate Abdominal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lomitapide mesylate Alanine aminotransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lomitapide mesylate Back pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lomitapide mesylate Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lomitapide mesylate Diarrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lomitapide mesylate Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lomitapide mesylate Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lomitapide mesylate Flatulence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lomitapide mesylate Gastrooesophageal reflux disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lomitapide mesylate Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lomitapide mesylate Hepatic steatosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lomitapide mesylate Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lomitapide mesylate Transaminases increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lomitapide mesylate Weight decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lomustine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lomustine Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lomustine Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Loperamide Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Loperamide Abdominal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Acute kidney injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Agitation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Loperamide Anxiety 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Arrhythmia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Loperamide Atrioventricular block first degree 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Bradycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Brain injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Brain oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Cardiotoxicity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Circulatory collapse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Loperamide Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Confusional state 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Congestive cardiomyopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Loperamide Depressed level of consciousness 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Loperamide Diarrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Loperamide Dizziness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Loperamide Drug abuse 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Drug dependence 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Drug withdrawal syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Loperamide Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Ejection fraction decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Loperamide Electrocardiogram QT prolonged 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Loperamide Electrocardiogram abnormal 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Loperamide Electrolyte imbalance 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Haemodynamic instability 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Hyperhidrosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Loperamide Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Hypoxia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Ileus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Intentional self-injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Loperamide Irritability 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Lethargy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Palpitations 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Pancreatitis acute 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Loperamide Pulmonary embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Loperamide Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Loperamide Respiratory depression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Rhabdomyolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Sinus bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Suicide attempt 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Syncope 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Loperamide Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Torsade de pointes 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Loperamide Tremor 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Loperamide Unresponsive to stimuli 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Ventricular arrhythmia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Ventricular fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide Ventricular tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Loperamide Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Loperamide hydrochloride Abdominal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide hydrochloride Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide hydrochloride Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Loperamide hydrochloride Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide hydrochloride Toxic epidermal necrolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Loperamide hydrochloride Urinary retention 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Loperamide hydrochloride Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Loratadine Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Loratadine Abdominal pain upper 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Loratadine Agitation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Loratadine Angioedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Loratadine Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Loratadine Arrhythmia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Loratadine Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Loratadine Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Loratadine Blood pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Loratadine Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Loratadine Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Loratadine Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Loratadine Dermatitis bullous 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Loratadine Diarrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Loratadine Epilepsy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Loratadine Feeling abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Loratadine Feeling hot 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Loratadine Heart rate increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Loratadine Hepatic function abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Loratadine Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Loratadine Hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Loratadine Lacrimation increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Loratadine Malaise 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Loratadine Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Loratadine Nightmare 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Loratadine Shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Loratadine Sneezing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Loratadine Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Loratadine Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Loratadine Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Loratadine Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lorazepam Abasia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Lorazepam Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Abdominal pain upper 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Acute kidney injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Aggression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Agitation 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Lorazepam Akathisia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Alanine aminotransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Altered state of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Amnesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Amylase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Anger 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Aphasia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Apnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Arthralgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Aspartate aminotransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Ataxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Balance disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Blood creatine phosphokinase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Blood creatinine increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Blood pressure decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Blood pressure increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Bradyphrenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Brain oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Burning sensation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Cardiogenic shock 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Catatonia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Chills 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Chronic obstructive pulmonary disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Coagulopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Cognitive disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Coma 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Contusion 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Crying 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Cystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Decreased appetite 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Delirium 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Delusion 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Lorazepam Dementia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Depressed level of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Disorientation 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Lorazepam Disturbance in attention 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Drug abuse 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Drug dependence 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Lorazepam Drug withdrawal syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Dyskinesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Dyspepsia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Dysphagia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Dyspnoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Dystonia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Eating disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Electrocardiogram QT prolonged 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Emotional disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Encephalopathy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Epilepsy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lorazepam Erythema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Extrapyramidal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Eyelid oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Fear 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Febrile neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Feeling cold 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Feeling jittery 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Gait disturbance 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Generalised tonic-clonic seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Haematemesis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Hallucination 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Hallucination, auditory 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Heart rate decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Heart rate increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Hyperreflexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Hypoaesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Hypokinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Hypothermia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Hypothyroidism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Hypotonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Hypoxia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Ileus paralytic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Inappropriate antidiuretic hormone secretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Incontinence 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Insomnia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Intentional self-injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Irritability 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Lactic acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Lethargy 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Lorazepam Leukocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Loss of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Malaise 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Mania 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Memory impairment 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Mental disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Mental impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Metabolic acidosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Miosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Mood altered 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lorazepam Mood swings 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Muscle atrophy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Muscle rigidity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Muscle spasms 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Muscle tightness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Muscle twitching 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Musculoskeletal stiffness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Mydriasis 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Lorazepam Myoclonus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Nasopharyngitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lorazepam Nausea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Neck pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Nervous system disorder 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Neuroleptic malignant syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Nightmare 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Obstructive airways disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lorazepam Oropharyngeal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lorazepam Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Oxygen saturation decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Pallor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Palpitations 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Lorazepam Paraesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Paralysis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Paranoia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Parkinsonism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Pericardial effusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Photophobia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Platelet count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Pneumonia aspiration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Lorazepam Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Pruritus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Psychotic disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Pyrexia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Lorazepam Renal impairment 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Respiratory depression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Respiratory distress 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Respiratory failure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Restless legs syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Restlessness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Sedation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Seizure 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Sepsis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Serotonin syndrome 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Sinusitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lorazepam Sleep apnoea syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Sleep disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Somnolence 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Sopor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Speech disorder 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Lorazepam Status epilepticus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Stress 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Stress cardiomyopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Stupor 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Sudden death 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Suicidal ideation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Suicide attempt 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Swelling face 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Swollen tongue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Tachycardia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Lorazepam Tachypnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Thinking abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Tremor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Unevaluable event 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Unresponsive to stimuli 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Urinary incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Vertigo 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Vision blurred 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Visual impairment 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Lorazepam Weight decreased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorazepam Weight increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lorazepam Withdrawal syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lorcaserin hydrochloride Cardiac failure congestive 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lorcaserin hydrochloride Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lorcaserin hydrochloride Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lorcaserin hydrochloride Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lorcaserin hydrochloride Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorcaserin hydrochloride Serotonin syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lorlatinib Asthenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorlatinib Blood cholesterol increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorlatinib Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorlatinib Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorlatinib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorlatinib Delirium 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorlatinib Diarrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorlatinib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorlatinib Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorlatinib Dyspnoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lorlatinib Gait disturbance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorlatinib Hallucination, visual 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lorlatinib Hyperlipidaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorlatinib Lung disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorlatinib Malaise 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorlatinib Neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorlatinib Neurotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lorlatinib Oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorlatinib Oedema peripheral 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorlatinib Pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorlatinib Pain in extremity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lorlatinib Pericardial effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorlatinib Pleural effusion 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Lorlatinib Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Lorlatinib Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorlatinib Pneumonitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorlatinib Pulmonary embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorlatinib Pyrexia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorlatinib Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lorlatinib Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lorlatinib Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorlatinib Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lorlatinib Thrombocytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Losartan Abdominal distension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Losartan Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Losartan Abdominal pain upper 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan Abdominal tenderness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Losartan Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Losartan Agitation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Losartan Alanine aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Losartan Alopecia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Losartan Amnesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Losartan Anaphylactic reaction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Losartan Angina pectoris 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Losartan Angioedema 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Losartan Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Losartan Atrial fibrillation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Losartan Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan Balance disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan Blindness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Losartan Blood creatinine increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Losartan Blood pressure fluctuation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Losartan Blood pressure increased 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Losartan Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Losartan Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Losartan Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Losartan Cardiac failure 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Losartan Chest discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Losartan Chest pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Losartan Chronic kidney disease 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan Coagulopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Losartan Colon cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Losartan Confusional state 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Losartan Contusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Losartan Cough 0.0 0.0 0.0 0.0 0.0 1.0 1.0 Losartan Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Losartan Decreased appetite 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Losartan Deep vein thrombosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Losartan Delirium 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Losartan Depressed level of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Losartan Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Losartan Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan Drug reaction with eosinophilia and systemic symptoms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Losartan Dysgeusia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Losartan Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Losartan Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Losartan Erythema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan Eye pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Losartan Feeling abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Losartan Gait disturbance 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Losartan Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Losartan Haemoglobin decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Losartan Haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Losartan Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Losartan Heart rate increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Losartan Hepatic cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Losartan Hypercalcaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Losartan Hyperglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Losartan Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Losartan Hyperkalaemia 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Losartan Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Losartan Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Losartan Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Losartan Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Losartan Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Losartan Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Losartan Hypoxia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Losartan Inflammation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Losartan Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan Joint swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Losartan Leukopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Losartan Lip swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan Liver disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Losartan Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Losartan Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Losartan Migraine 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Losartan Muscle spasms 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Losartan Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan Musculoskeletal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan Musculoskeletal stiffness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Losartan Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Losartan Myopathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Losartan Nasal congestion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Losartan Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Losartan Neck pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Losartan Nightmare 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Losartan Orthostatic hypotension 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Losartan Oxygen saturation decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Losartan Pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Losartan Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan Pain of skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Losartan Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Losartan Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Losartan Pancreatitis acute 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Losartan Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan Pharyngeal oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Losartan Platelet count decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Losartan Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Losartan Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Losartan Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Losartan Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Losartan Renal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Losartan Renal failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Losartan Renal impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Losartan Respiratory disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Losartan Respiratory distress 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Losartan Respiratory failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Losartan Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Losartan Sepsis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Losartan Shock 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Losartan Skin discolouration 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan Skin reaction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan Sleep disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Losartan Speech disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Losartan Stevens-Johnson syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Losartan Stress 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Losartan Swollen tongue 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Losartan Syncope 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Losartan Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Losartan Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan Toxic epidermal necrolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Losartan Tremor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Losartan Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Losartan Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Losartan Weight increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Losartan potassium Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan potassium Angioedema 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Losartan potassium Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Losartan potassium Arrhythmia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Losartan potassium Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan potassium Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Losartan potassium Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan potassium Blood bilirubin increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Losartan potassium Blood creatinine increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Losartan potassium Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Losartan potassium Chest pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan potassium Confusional state 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan potassium Constipation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Losartan potassium Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Losartan potassium Decreased appetite 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Losartan potassium Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan potassium Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Losartan potassium Dysgeusia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Losartan potassium Dyspnoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Losartan potassium Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Losartan potassium Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Losartan potassium Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Losartan potassium Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Losartan potassium Hyperkalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Losartan potassium Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan potassium Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Losartan potassium Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Losartan potassium Insomnia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Losartan potassium Joint swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Losartan potassium Migraine 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Losartan potassium Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan potassium Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan potassium Musculoskeletal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan potassium Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan potassium Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Losartan potassium Nausea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Losartan potassium Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan potassium Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Losartan potassium Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan potassium Palpitations 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Losartan potassium Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan potassium Pollakiuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Losartan potassium Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan potassium Rash 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Losartan potassium Sleep disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan potassium Tachycardia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Losartan potassium Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan potassium Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan potassium Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Losartan potassium Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Loteprednol etabonate Eye pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Loteprednol etabonate Intraocular pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Loteprednol etabonate Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lovastatin Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lovastatin Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lovastatin Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lovastatin Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lovastatin Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lovastatin Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lubiprostone Blood pressure decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lubiprostone Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lubiprostone Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lubiprostone Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Lubiprostone Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lubiprostone Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lurasidone Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Lurasidone hydrochloride Agitation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Lurasidone hydrochloride Akathisia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lurasidone hydrochloride Angioedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lurasidone hydrochloride Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lurasidone hydrochloride Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lurasidone hydrochloride Blood creatine phosphokinase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lurasidone hydrochloride Cerebrovascular accident 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lurasidone hydrochloride Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lurasidone hydrochloride Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lurasidone hydrochloride Dystonia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Lurasidone hydrochloride Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lurasidone hydrochloride Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lurasidone hydrochloride Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lurasidone hydrochloride Panic attack 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lurasidone hydrochloride Parkinsonism 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lurasidone hydrochloride Restlessness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Lurasidone hydrochloride Rhabdomyolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lurasidone hydrochloride Somnolence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Lurasidone hydrochloride Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Lurasidone hydrochloride Vision blurred 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Macitentan Abasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Abdominal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Abdominal distension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Abdominal pain 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Abnormal dreams 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Abnormal faeces 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Abscess 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Acidosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Macitentan Acne 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Acute coronary syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Acute myeloid leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Macitentan Acute myocardial infarction 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Macitentan Acute respiratory failure 1.0 1.0 1.0 0.0 1.0 0.0 0.0 Macitentan Agitation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Alanine aminotransferase increased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Alopecia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Altered state of consciousness 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Amnesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Anaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Anal incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Anger 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Angioedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Angiopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Anuria 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Macitentan Anxiety 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Macitentan Apathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Aphasia 1.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Appendicitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Arrhythmia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Arthritis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Arthropathy 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Ascites 1.0 1.0 1.0 0.0 1.0 0.0 0.0 Macitentan Aspartate aminotransferase increased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Asphyxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Asthenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Asthma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Atelectasis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Atrial fibrillation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Atrial flutter 1.0 1.0 1.0 0.0 1.0 0.0 0.0 Macitentan Atrial septal defect 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Back pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Bacteraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Bacterial infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Balance disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Macitentan Blister 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Blood alkaline phosphatase increased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Blood bilirubin increased 1.0 1.0 1.0 0.0 1.0 0.0 0.0 Macitentan Blood cholesterol increased 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Blood count abnormal 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Blood creatinine increased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Blood disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Blood glucose decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Blood magnesium decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Blood potassium decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Blood potassium increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Blood pressure abnormal 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Blood pressure decreased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Blood pressure fluctuation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Blood sodium decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Blood urea increased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Blood urine present 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Bone pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Bradycardia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Bronchospasm 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Burning sensation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan C-reactive protein increased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Candida infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Cardiac arrest 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Cardiac disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Cardiac failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Cardiac failure acute 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Cardiac failure congestive 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Cardiac tamponade 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Macitentan Cardiogenic shock 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Cardiomegaly 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Cardiopulmonary failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Macitentan Cardiovascular disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Cataract 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Cellulitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Cerebral haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Cerebral infarction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Cerebrovascular accident 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Chills 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Choking 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Cholecystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Cholecystitis acute 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Cholelithiasis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Chromaturia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Chronic kidney disease 1.0 1.0 1.0 1.0 0.0 0.0 0.0 Macitentan Chronic obstructive pulmonary disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Clostridium difficile colitis 1.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Clostridium difficile infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Coagulopathy 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Cognitive disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Colon cancer 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Coma 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Confusional state 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Connective tissue disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Constipation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Contusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Coordination abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Coronary artery disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Cough 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Cyanosis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Cyst 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Cystitis 0.0 0.0 1.0 0.0 1.0 0.0 0.0 Macitentan Deafness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Macitentan Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Macitentan Decreased appetite 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Decubitus ulcer 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Deep vein thrombosis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Dehydration 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Delirium 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Dementia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Depressed mood 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Depression 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Diabetes mellitus 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Diarrhoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Diplopia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Discomfort 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Disease progression 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Disease recurrence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Disturbance in attention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Diverticulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Dizziness 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Dizziness postural 0.0 0.0 1.0 0.0 1.0 0.0 0.0 Macitentan Drug hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Drug intolerance 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Drug withdrawal syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Dry eye 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Dry mouth 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Dry skin 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Dry throat 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Dysarthria 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Dysgeusia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Dyskinesia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Dyspepsia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Dysphagia 1.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Dysphonia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Dyspnoea exertional 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Dysstasia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Dysuria 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Ear disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Ear infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Ear pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Eating disorder 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Ejection fraction decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Electrocardiogram abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Electrolyte imbalance 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Embolism 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Macitentan Epistaxis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Erythema 0.0 0.0 1.0 0.0 1.0 0.0 0.0 Macitentan Eye disorder 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Eye haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Eye irritation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Eye pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Eye pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Eye swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Face oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Facial paralysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Faecaloma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Faeces discoloured 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Failure to thrive 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Fatigue 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Feeling abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Feeling cold 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Feeling hot 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Feeling jittery 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Femur fracture 1.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Flank pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Flatulence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Fluid overload 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Fluid retention 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Flushing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Fracture 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Full blood count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Fungal infection 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Fungal skin infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Gallbladder disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Gamma-glutamyltransferase increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Gastric disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Gastric haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Gastric ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Gastritis 1.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Gastroenteritis viral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Gastrointestinal disorder 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Gastrointestinal haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Gastrointestinal pain 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Gastrooesophageal reflux disease 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Generalised oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Gingival bleeding 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Gingivitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Glaucoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Gout 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Haematemesis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Haematochezia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Haematocrit decreased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Haematuria 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Haemodynamic instability 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Macitentan Haemoglobin decreased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Haemoptysis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Hallucination 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Headache 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Heart rate decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Heart rate irregular 0.0 0.0 1.0 0.0 1.0 0.0 0.0 Macitentan Hemiparesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Hemiplegia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Hepatic cancer 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Macitentan Hepatic cirrhosis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Hepatic encephalopathy 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Hepatic enzyme increased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Hepatic failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Hepatic function abnormal 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Hepatomegaly 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Hepatotoxicity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Hernia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Herpes zoster 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Hip fracture 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Hot flush 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Hyperglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Hyperkalaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Hyperlipidaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Hypersomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Hypoacusis 1.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Hypoaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Hypoglycaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Hypokalaemia 1.0 1.0 1.0 0.0 1.0 0.0 0.0 Macitentan Hypokinesia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Hyponatraemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Hypotension 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Hypothyroidism 1.0 1.0 1.0 1.0 0.0 0.0 0.0 Macitentan Hypovolaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Hypoxia 1.0 1.0 1.0 0.0 1.0 0.0 0.0 Macitentan Ileus 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Ill-defined disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Increased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Inflammation 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Influenza like illness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Insomnia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Interstitial lung disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Intervertebral disc protrusion 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Intestinal obstruction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Intestinal perforation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Macitentan Iron deficiency anaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Irritability 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Irritable bowel syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Ischaemic stroke 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Jaundice 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Macitentan Joint swelling 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Laboratory test abnormal 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Laceration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Lacrimation increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Laryngitis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Left ventricular dysfunction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Lethargy 1.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Leukaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Limb discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Lip swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Liver disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Liver function test abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Macitentan Liver function test increased 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Macitentan Liver injury 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Macitentan Local swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Localised infection 1.0 0.0 1.0 0.0 1.0 0.0 0.0 Macitentan Loss of consciousness 1.0 0.0 1.0 0.0 1.0 0.0 0.0 Macitentan Lower respiratory tract infection 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Lung disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Lung infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Lung infiltration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Lung neoplasm malignant 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Macitentan Lymphadenopathy 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Malaise 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Malignant melanoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Malnutrition 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Melaena 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Memory impairment 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Menorrhagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Mental disorder 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Mental impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Mental status changes 1.0 1.0 1.0 1.0 0.0 0.0 0.0 Macitentan Metastatic neoplasm 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Macitentan Migraine 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Mobility decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Mood altered 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Movement disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Macitentan Muscle spasms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Muscle twitching 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Muscular weakness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Musculoskeletal chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Musculoskeletal discomfort 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Musculoskeletal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Musculoskeletal stiffness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Myalgia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Myocardial infarction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Nasal congestion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Nasal dryness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Nausea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Neck pain 0.0 0.0 1.0 1.0 1.0 0.0 0.0 Macitentan Neoplasm malignant 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Macitentan Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Nephropathy 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Nervous system disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Nervousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Neuralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Neuropathy peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Night sweats 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Obesity 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Obstructive airways disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Ocular hyperaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Oedema peripheral 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Oral discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Oral pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Oropharyngeal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Orthostatic hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Osteomyelitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Osteoporosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Oxygen saturation decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Pain in jaw 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Pain of skin 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Pallor 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Pancreatic carcinoma 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Pancreatitis acute 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Pancytopenia 1.0 1.0 1.0 1.0 0.0 0.0 0.0 Macitentan Panic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Paraesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Paraesthesia oral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Paralysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Parkinson's disease 1.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Pericardial effusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Peripheral coldness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Peripheral swelling 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Peripheral vascular disorder 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Peritonitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Macitentan Petechiae 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Photophobia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Platelet count decreased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Pleural effusion 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Pleurisy 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Pneumonia aspiration 1.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Pneumonia bacterial 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Pneumonitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Pneumothorax 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Pollakiuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Polyp 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Polyuria 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Poor quality sleep 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Productive cough 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Prostate cancer 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Macitentan Prostatic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Pruritus 1.0 0.0 1.0 1.0 1.0 0.0 0.0 Macitentan Pruritus generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Pulmonary congestion 1.0 1.0 1.0 1.0 0.0 0.0 0.0 Macitentan Pulmonary embolism 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Pulmonary fibrosis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Pulmonary function test decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Pulmonary haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Pulmonary hypertension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Pulmonary mass 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Pulmonary oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Pyrexia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Rales 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Rash erythematous 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Rash generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Rash macular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Rash pruritic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Raynaud's phenomenon 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Red blood cell count decreased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Renal disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Renal failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Renal impairment 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Renal pain 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Respiratory arrest 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Respiratory disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Respiratory distress 1.0 0.0 1.0 0.0 1.0 0.0 0.0 Macitentan Respiratory failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Respiratory tract congestion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Respiratory tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Restless legs syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Restlessness 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Retching 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Rheumatoid arthritis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Rhinorrhoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Salivary hypersecretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Scab 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Sciatica 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Seizure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Sepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Septic shock 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Macitentan Sinus congestion 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Sinus disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Sinus tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Sinusitis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Skin burning sensation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Skin discolouration 0.0 1.0 1.0 0.0 1.0 0.0 0.0 Macitentan Skin disorder 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Skin exfoliation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Skin infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Skin irritation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Skin lesion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Skin ulcer 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Sleep apnoea syndrome 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Sleep disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Sluggishness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Small intestinal obstruction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Sneezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Somnolence 1.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Speech disorder 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Spinal compression fracture 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Spinal fracture 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Staphylococcal infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Stomatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Stress 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Subdural haematoma 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Macitentan Suicidal ideation 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Supraventricular tachycardia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Swelling 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Swelling face 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Syncope 1.0 0.0 1.0 0.0 1.0 0.0 0.0 Macitentan Systemic lupus erythematosus 1.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Tachycardia 1.0 1.0 1.0 0.0 1.0 0.0 0.0 Macitentan Tension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Thinking abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Macitentan Thirst 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Throat irritation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Throat tightness 0.0 0.0 1.0 0.0 1.0 0.0 0.0 Macitentan Thrombocytopenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Tinnitus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Tooth abscess 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Tooth disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Toothache 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Transaminases increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Transient ischaemic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Tremor 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Troponin increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Unevaluable event 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Unresponsive to stimuli 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Upper gastrointestinal haemorrhage 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Upper limb fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Upper respiratory tract infection 0.0 1.0 1.0 0.0 1.0 0.0 0.0 Macitentan Urinary incontinence 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Urinary retention 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Urinary tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Urine output decreased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Macitentan Urticaria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Vaginal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Varicose vein 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Ventricular tachycardia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Vision blurred 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Visual acuity reduced 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Visual impairment 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan Vomiting 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Weight decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Weight increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Macitentan Wheezing 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Macitentan White blood cell count decreased 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Macitentan White blood cell count increased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Magnesium oxide Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mannitol Acute kidney injury 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mannitol Chest discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mannitol Chills 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mannitol Discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mannitol Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mannitol Dyspnoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mannitol Hyperkalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mannitol Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mannitol Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mannitol Pyrexia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mannitol Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mannitol Rash erythematous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mannitol Renal failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mannitol Renal impairment 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Mannitol Tremor 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mannitol Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Maraviroc Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Maraviroc Drug resistance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Maraviroc Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Maraviroc Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Maraviroc Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mebendazole Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mechlorethamine Cardiac disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mechlorethamine Cerebrovascular accident 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mechlorethamine Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mechlorethamine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mechlorethamine Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mechlorethamine Hip fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mechlorethamine Malignant neoplasm progression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mechlorethamine Myocardial infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mechlorethamine Neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mechlorethamine Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Mechlorethamine Pulmonary mass 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mechlorethamine Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mechlorethamine Skin reaction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mechlorethamine Skin ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mechlorethamine Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meclizine hydrochloride Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Medroxyprogesterone Haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Medroxyprogesterone Injection site pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Medroxyprogesterone Injection site reaction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Medroxyprogesterone acetate Abdominal distension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Medroxyprogesterone acetate Abdominal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Medroxyprogesterone acetate Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Medroxyprogesterone acetate Acne 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Medroxyprogesterone acetate Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Medroxyprogesterone acetate Amenorrhoea 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Medroxyprogesterone acetate Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Medroxyprogesterone acetate Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Medroxyprogesterone acetate Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Medroxyprogesterone acetate Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Medroxyprogesterone acetate Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Medroxyprogesterone acetate Blood cholesterol increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Medroxyprogesterone acetate Breast pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Medroxyprogesterone acetate Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Medroxyprogesterone acetate Cerebrovascular accident 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Medroxyprogesterone acetate Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Medroxyprogesterone acetate Chills 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Medroxyprogesterone acetate Colitis ulcerative 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Medroxyprogesterone acetate Crohn's disease 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Medroxyprogesterone acetate Crying 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Medroxyprogesterone acetate Cystitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Medroxyprogesterone acetate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Medroxyprogesterone acetate Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Medroxyprogesterone acetate Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Medroxyprogesterone acetate Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Medroxyprogesterone acetate Disturbance in attention 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Medroxyprogesterone acetate Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Medroxyprogesterone acetate Drug hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Medroxyprogesterone acetate Drug interaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Medroxyprogesterone acetate Dysmenorrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Medroxyprogesterone acetate Dyspnoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Medroxyprogesterone acetate Epilepsy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Medroxyprogesterone acetate Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Medroxyprogesterone acetate Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Medroxyprogesterone acetate Feeling abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Medroxyprogesterone acetate Haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Medroxyprogesterone acetate Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Medroxyprogesterone acetate Heart rate increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Medroxyprogesterone acetate Hot flush 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Medroxyprogesterone acetate Hyperhidrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Medroxyprogesterone acetate Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Medroxyprogesterone acetate Hypoaesthesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Medroxyprogesterone acetate Infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Medroxyprogesterone acetate Inflammation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Medroxyprogesterone acetate Influenza 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Medroxyprogesterone acetate Injection site pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Medroxyprogesterone acetate Injection site reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Medroxyprogesterone acetate Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Medroxyprogesterone acetate Irritability 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Medroxyprogesterone acetate Libido decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Medroxyprogesterone acetate Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Medroxyprogesterone acetate Metrorrhagia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Medroxyprogesterone acetate Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Medroxyprogesterone acetate Mood swings 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Medroxyprogesterone acetate Muscle spasms 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Medroxyprogesterone acetate Musculoskeletal disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Medroxyprogesterone acetate Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Medroxyprogesterone acetate Nasopharyngitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Medroxyprogesterone acetate Nausea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Medroxyprogesterone acetate Nervousness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Medroxyprogesterone acetate Osteoporosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Medroxyprogesterone acetate Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Medroxyprogesterone acetate Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Medroxyprogesterone acetate Palpitations 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Medroxyprogesterone acetate Panic attack 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Medroxyprogesterone acetate Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Medroxyprogesterone acetate Paraesthesia oral 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Medroxyprogesterone acetate Peripheral swelling 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Medroxyprogesterone acetate Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Medroxyprogesterone acetate Pulmonary embolism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Medroxyprogesterone acetate Sinusitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Medroxyprogesterone acetate Skin odour abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Medroxyprogesterone acetate Suicidal ideation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Medroxyprogesterone acetate Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Medroxyprogesterone acetate Urinary tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Medroxyprogesterone acetate Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Medroxyprogesterone acetate Vaginal haemorrhage 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Medroxyprogesterone acetate Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Medroxyprogesterone acetate Vomiting 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Medroxyprogesterone acetate Weight decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Medroxyprogesterone acetate Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Medroxyprogesterone acetate White blood cell count increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mefloquine Abnormal dreams 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mefloquine Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mefloquine Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mefloquine Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mefloquine Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mefloquine Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mefloquine Nightmare 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mefloquine Paranoia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mefloquine Sleep disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mefloquine Vertigo 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mefloquine hydrochloride Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mefloquine hydrochloride Confusional state 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mefloquine hydrochloride Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mefloquine hydrochloride Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mefloquine hydrochloride Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mefloquine hydrochloride Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mefloquine hydrochloride Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mefloquine hydrochloride Panic attack 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mefloquine hydrochloride Suicidal ideation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mefloquine hydrochloride Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mefloquine hydrochloride Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mefloquine hydrochloride Vertigo 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mefloquine hydrochloride Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Megestrol Pulmonary embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meloxicam Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meloxicam Acute myocardial infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meloxicam Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Meloxicam Anaphylactic reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Meloxicam Angina pectoris 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meloxicam Arthralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Arthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Arthropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Asthenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Meloxicam Back pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Blister 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Meloxicam Bursitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Meloxicam Cardiac failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meloxicam Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meloxicam Chest discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Meloxicam Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meloxicam Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Meloxicam Conjunctivitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Meloxicam Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meloxicam Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meloxicam Diarrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Disease progression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Meloxicam Drug hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Drug reaction with eosinophilia and systemic symptoms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meloxicam Drug resistance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Duodenal ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meloxicam Dyspnoea 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Meloxicam Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meloxicam Erythema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Faeces discoloured 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Meloxicam Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Feeling abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Gait disturbance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Gastric haemorrhage 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Meloxicam Gastric ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meloxicam Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meloxicam Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meloxicam Gastrointestinal haemorrhage 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Meloxicam Haematemesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meloxicam Haematochezia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Meloxicam Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meloxicam Headache 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Meloxicam Heart rate decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Meloxicam Heart rate increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Hepatic enzyme increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Meloxicam Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meloxicam Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Meloxicam Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Meloxicam Hypovolaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meloxicam Inflammation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Insomnia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Meloxicam Interstitial lung disease 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Meloxicam Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meloxicam Joint swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Liver disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Loss of consciousness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Meloxicam Lung disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Malaise 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Melaena 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meloxicam Musculoskeletal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Meloxicam Ocular hyperaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meloxicam Pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Meloxicam Pain in extremity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Peptic ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meloxicam Peripheral swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Psoriasis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Meloxicam Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meloxicam Rash pruritic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meloxicam Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Meloxicam Respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Meloxicam Rheumatoid arthritis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Meloxicam Sepsis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meloxicam Shock haemorrhagic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meloxicam Sinus tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meloxicam Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Meloxicam Swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Meloxicam Swelling face 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Toxic epidermal necrolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meloxicam Treatment failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Tremor 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Unresponsive to stimuli 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meloxicam Upper gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meloxicam Upper respiratory tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meloxicam Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meloxicam Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meloxicam Wheezing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Melphalan Acute kidney injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Melphalan Acute myeloid leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Melphalan Alanine aminotransferase increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Melphalan Aspartate aminotransferase increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Melphalan Asthenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Melphalan Blood alkaline phosphatase increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Melphalan Blood bilirubin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Melphalan Bone marrow failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Melphalan Bronchospasm 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Melphalan Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Melphalan Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Melphalan Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Melphalan Dyspnoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Melphalan Febrile neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Melphalan Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Melphalan Infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Melphalan Interstitial lung disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Melphalan Lung disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Melphalan Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Melphalan Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Melphalan Neutropenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Melphalan Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Melphalan Plasma cell myeloma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Melphalan Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Melphalan Posterior reversible encephalopathy syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Melphalan Pyrexia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Melphalan Rash 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Melphalan Respiratory distress 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Melphalan Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Melphalan Retinal detachment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Melphalan Retinal haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Melphalan Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Melphalan Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Melphalan Stomatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Melphalan Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Memantine Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Aggression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Agitation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Memantine Altered state of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Memantine Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Memantine Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Balance disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Memantine Blood creatine phosphokinase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Memantine Cardiac failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Confusional state 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Memantine Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Memantine Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Deep vein thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Delusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Depressed level of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Memantine Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Dizziness 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Memantine Dyskinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Memantine Dyspnoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Memantine Encephalopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Memantine Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Gait disturbance 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Memantine Generalised tonic-clonic seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Hallucination 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Memantine Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Memantine Heart rate decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Hepatic function abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Hyperhidrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Memantine Hypernatraemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Memantine Hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Memantine Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Memantine Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Hypoxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Ileus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Inappropriate antidiuretic hormone secretion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Memantine Incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Memantine Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Liver disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Liver function test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Lung neoplasm malignant 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Mania 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Mental impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Memantine Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Muscle spasms 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Memantine Myoclonus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Memantine Nervousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Memantine Pallor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Paranoia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Memantine Parkinsonism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Memantine Photophobia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Memantine Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Pneumonia aspiration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Pollakiuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Memantine Psychomotor hyperactivity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Memantine Psychotic disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Memantine Pulmonary embolism 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Memantine Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Somnolence 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Memantine Sopor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Memantine Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Tremor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Memantine Unresponsive to stimuli 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine Vertigo 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Memantine Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Memantine Withdrawal syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Agitation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Memantine hydrochloride Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Aphasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Asthenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Coma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Confusional state 0.0 0.0 1.0 0.0 0.0 1.0 0.0 Memantine hydrochloride Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Cough 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Decreased appetite 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Deep vein thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Dehydration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Dizziness 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Memantine hydrochloride Dyskinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Dysphagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Encephalopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Fatigue 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Leukopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Loss of consciousness 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Myoclonus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Paraesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Pulmonary embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Sepsis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Suicidal ideation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Memantine hydrochloride Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Thrombocytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Urinary incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Urinary tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Memantine hydrochloride Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meperidine hydrochloride Anaphylactic reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meperidine hydrochloride Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Meperidine hydrochloride Delirium 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meperidine hydrochloride Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meperidine hydrochloride Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meperidine hydrochloride Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Meperidine hydrochloride Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meperidine hydrochloride Seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meperidine hydrochloride Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meperidine hydrochloride Vomiting 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mercaptopurine Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Alanine aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mercaptopurine Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mercaptopurine Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Aspartate aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Bacterial infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Blood bilirubin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Bone marrow failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mercaptopurine Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Coagulopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Depression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Diarrhoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Febrile neutropenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Gastrointestinal disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mercaptopurine Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Hepatotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mercaptopurine Hypoglycaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mercaptopurine Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Mouth ulceration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Mucosal inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Myelodysplastic syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Neutropenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Neutrophil count decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Pancytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Platelet count decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Pneumocystis jirovecii pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Pneumonia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Sepsis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Septic shock 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Stomatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mercaptopurine White blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meropenem Abdominal pain upper 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Meropenem Acute kidney injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Acute respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Meropenem Agranulocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Anaphylactic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Anuria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Meropenem Asthenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Blister 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Blood pressure decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Bone marrow failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Meropenem C-reactive protein increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Candida infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Clostridium difficile colitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Clostridium difficile infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Meropenem Cyanosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Meropenem Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Meropenem Depressed level of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Dermatitis bullous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meropenem Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meropenem Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Meropenem Disseminated intravascular coagulation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Meropenem Drug hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Drug resistance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Meropenem Dysgeusia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Meropenem Dyspnoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Encephalopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Meropenem Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meropenem Epilepsy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Erythema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Meropenem Face oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meropenem Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meropenem Flushing 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Meropenem Fungal infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Meropenem Gastrointestinal disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Meropenem Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meropenem Haemorrhage intracranial 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Meropenem Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Meropenem Hepatic failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meropenem Hyperkalaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Meropenem Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Liver function test abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Meropenem Loss of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Malaise 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Metabolic acidosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Meropenem Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Nausea 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Meropenem Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meropenem Pancytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Peripheral swelling 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Meropenem Platelet count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Pleural effusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Meropenem Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Meropenem Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Meropenem Premature baby 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Meropenem Pruritus 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Meropenem Pruritus generalised 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Meropenem Pseudomembranous colitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Pulmonary embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Meropenem Pulmonary haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Meropenem Pyrexia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Rash 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Meropenem Rash macular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meropenem Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Respiratory distress 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Stevens-Johnson syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Tachycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Toxic epidermal necrolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem Treatment failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Meropenem Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Meropenem White blood cell count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Meropenem White blood cell count increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mesalamine Abdominal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mesalamine Acute kidney injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mesalamine Agranulocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mesalamine Alanine aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mesalamine Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mesalamine Anal incontinence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mesalamine Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mesalamine Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mesalamine Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mesalamine Blood alkaline phosphatase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mesalamine Bone marrow failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mesalamine Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mesalamine Chronic kidney disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mesalamine Colitis ulcerative 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mesalamine Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mesalamine Crohn's disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mesalamine Diarrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mesalamine Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mesalamine Dysphagia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mesalamine Dyspnoea 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Mesalamine Erythema multiforme 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mesalamine Flatulence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mesalamine Frequent bowel movements 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mesalamine Haematochezia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mesalamine Haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mesalamine Haemorrhoids 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mesalamine Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mesalamine Hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mesalamine Hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mesalamine Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mesalamine Interstitial lung disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mesalamine Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mesalamine Lipase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mesalamine Liver function test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mesalamine Muscle spasms 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mesalamine Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mesalamine Myocarditis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mesalamine Nervousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mesalamine Pericardial effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mesalamine Pericarditis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mesalamine Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mesalamine Pleurisy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mesalamine Psoriasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mesalamine Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mesalamine Rash 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mesalamine Rectal haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mesalamine Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mesalamine Somnolence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mesalamine Stomatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mesalamine Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mesalamine Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mesalamine Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mesna Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mesna Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mesna Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mesna Face oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mesna Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mesna Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metaxalone Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Metaxalone Coma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Metaxalone Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Metaxalone Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Metaxalone Depressed level of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Metaxalone Electrocardiogram QT prolonged 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Metaxalone Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metaxalone Hyperreflexia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Metaxalone Hypotension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Metaxalone Metabolic acidosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Metaxalone Mydriasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metaxalone Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Metaxalone Respiratory depression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Metformin hydrochloride Abdominal discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metformin hydrochloride Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metformin hydrochloride Abnormal faeces 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metformin hydrochloride Asthenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metformin hydrochloride Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metformin hydrochloride Constipation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metformin hydrochloride Diarrhoea 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Metformin hydrochloride Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Metformin hydrochloride Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metformin hydrochloride Dyspnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metformin hydrochloride Flushing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metformin hydrochloride Headache 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Metformin hydrochloride Hypoglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metformin hydrochloride Influenza 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metformin hydrochloride Myalgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Metformin hydrochloride Nausea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metformin hydrochloride Palpitations 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metformin hydrochloride Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metformin hydrochloride Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Methadone hydrochloride Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methadone hydrochloride Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methadone hydrochloride Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methadone hydrochloride Cardiomyopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methadone hydrochloride Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methadone hydrochloride Constipation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methadone hydrochloride Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methadone hydrochloride Depression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methadone hydrochloride Diarrhoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methadone hydrochloride Disorientation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methadone hydrochloride Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methadone hydrochloride Dysphoria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methadone hydrochloride Electrocardiogram QT prolonged 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methadone hydrochloride Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Methadone hydrochloride Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methadone hydrochloride Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methadone hydrochloride Insomnia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methadone hydrochloride Nausea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methadone hydrochloride Oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methadone hydrochloride Pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Methadone hydrochloride Pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methadone hydrochloride Pyrexia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methadone hydrochloride Respiratory depression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methadone hydrochloride Restlessness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methadone hydrochloride Sedation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Methadone hydrochloride Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methadone hydrochloride Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methadone hydrochloride Tachycardia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Methadone hydrochloride Thrombocytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methadone hydrochloride Torsade de pointes 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Methadone hydrochloride Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methadone hydrochloride Ventricular fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methadone hydrochloride Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methadone hydrochloride Vomiting 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methimazole Acute hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methimazole Agranulocytosis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Methimazole Ascites 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methimazole Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methimazole Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methimazole Hepatitis cholestatic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methimazole Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methimazole Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methimazole Oropharyngeal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methimazole Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methimazole Pancytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methimazole Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methimazole Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methimazole Premature delivery 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methimazole Pulmonary alveolar haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methimazole Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methimazole Respiratory distress 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methimazole Rhabdomyolysis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methimazole Septic shock 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methimazole Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methimazole Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methocarbamol Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methocarbamol Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methocarbamol Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Abasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Abdominal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Abdominal distension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Abdominal pain upper 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Abscess 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Acne 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Acute coronary syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Acute myeloid leukaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Acute myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Acute respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Ageusia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Agitation 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Methotrexate Agranulocytosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Alanine aminotransferase increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Altered state of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Angina pectoris 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Angioedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Anuria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Aphasia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Methotrexate Aphthous ulcer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Aplastic anaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Appendicitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Appetite disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Arrhythmia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Arthritis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Arthropathy 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Ascites 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Aspartate aminotransferase increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Asthma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Ataxia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Atelectasis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Back pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Bacteraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Bacterial infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Balance disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Basal cell carcinoma 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Blister 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Blood alkaline phosphatase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Blood bilirubin increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Blood cholesterol increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Blood creatinine increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Blood glucose increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Blood pressure abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Blood pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Blood urea increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Body temperature increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Bone marrow failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Bone pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Breast cancer 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Bronchitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Bronchospasm 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Burning sensation 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate C-reactive protein increased 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Cachexia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Candida infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Cardiac disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Cardiac tamponade 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Cardiomyopathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Carpal tunnel syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Cerebral infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Cerebrovascular accident 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Chest discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Chest pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Chills 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Cholangitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Cholestasis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Chronic obstructive pulmonary disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Circulatory collapse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Clostridium difficile infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Coagulopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Cognitive disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Cold sweat 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Colitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Colitis ulcerative 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Confusional state 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Methotrexate Constipation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Contusion 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Crohn's disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Cyanosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Cyst 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Cystitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Deafness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Decubitus ulcer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Deep vein thrombosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Dementia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Depressed level of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Depressed mood 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Depression 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Dermatitis allergic 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Diarrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Diarrhoea haemorrhagic 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Discomfort 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Disease recurrence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Disseminated intravascular coagulation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Disturbance in attention 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Diverticulitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Drug eruption 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Drug hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Drug resistance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Drug-induced liver injury 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Dry skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Dysphagia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Dysphonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Dyspnoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Dysstasia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Electrolyte imbalance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Emotional disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Encephalitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Encephalopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Enteritis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Eosinophilia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Epilepsy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Epistaxis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Erythema multiforme 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Eye disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Eye haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Eye swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Eyelid oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Face oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Facial paralysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Faeces discoloured 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Febrile neutropenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Feeling abnormal 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Feeling hot 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Femur fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Flatulence 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Flushing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Foetal growth restriction 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Methotrexate Folliculitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Fracture 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Frequent bowel movements 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Fungal infection 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Methotrexate Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Gastric disorder 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Gastric ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Gastrointestinal disorder 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Gastrooesophageal reflux disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Generalised tonic-clonic seizure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Glossodynia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Haematemesis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Haematochezia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Haematocrit decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Haematuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Haemoglobin decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Haemolysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Haemoptysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Headache 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Heart rate increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Hemiparesis 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Methotrexate Hemiplegia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Hepatic cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Hepatic cirrhosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Hepatic encephalopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Hepatic enzyme abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Hepatic enzyme increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Hepatic function abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Hepatic steatosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Hepatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Hepatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Hepatocellular injury 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Hepatotoxicity 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Hernia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Herpes simplex 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Herpes zoster 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Hip fracture 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Hot flush 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Hyperglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Hypernatraemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Hyperthermia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Hypoaesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Hypokinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Hypophagia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Hypothyroidism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Hypoxia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Ill-defined disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Induration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Inflammation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Influenza 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Interstitial lung disease 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Intervertebral disc protrusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Intestinal obstruction 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Methotrexate Intestinal perforation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Irritable bowel syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Ischaemic stroke 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Joint stiffness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Joint swelling 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Keratitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Laboratory test abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Lacrimation increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Lethargy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Leukaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Leukocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Limb discomfort 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Liver disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Liver function test abnormal 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Liver function test increased 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Liver injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Localised infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Loss of consciousness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Lower respiratory tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Lung disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Lung infiltration 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Lung neoplasm malignant 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Lymphadenopathy 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Methotrexate Lymphoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Lymphopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Malaise 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Malignant melanoma 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Malnutrition 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Melaena 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Menstrual disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Mental disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Mental status changes 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Metastases to central nervous system 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Metastases to liver 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Metastases to lung 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Middle insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Migraine 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Mobility decreased 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Mood swings 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Motor dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Mouth ulceration 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Movement disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Mucosal inflammation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Muscle spasms 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Muscular weakness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Musculoskeletal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Musculoskeletal disorder 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Musculoskeletal pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Musculoskeletal stiffness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Myelodysplastic syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Nail disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Nasal congestion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Nasopharyngitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Neck pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Neoplasm 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Nephrolithiasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Nephropathy toxic 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Nervous system disorder 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Neurological symptom 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Neurotoxicity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Night sweats 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Nightmare 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Nodule 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Obesity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Obstructive airways disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Oesophagitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Oliguria 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Oral candidiasis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Oral discomfort 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Oral pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Oropharyngeal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Osteoarthritis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Osteomyelitis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Osteonecrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Osteoporosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Pain in extremity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Pain in jaw 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Pain of skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Pancreatitis acute 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Pancytopenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Panic attack 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Paralysis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Paresis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Pericardial effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Pericarditis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Peritonitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Petechiae 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Pharyngeal oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Pharyngitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Photophobia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Photosensitivity reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Platelet count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Pleural effusion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Pleurisy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Pneumocystis jirovecii pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Pneumonia bacterial 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Pneumonitis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Pneumothorax 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Polyp 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Polyuria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Poor quality sleep 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Posterior reversible encephalopathy syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Methotrexate Premature delivery 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Proctalgia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Prostate cancer 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Proteinuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Pruritus generalised 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Psoriasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Pulmonary alveolar haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Pulmonary congestion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Pulmonary embolism 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Pulmonary fibrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Pulmonary function test decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Pulmonary mass 0.0 0.0 0.0 0.0 1.0 0.0 1.0 Methotrexate Pulmonary oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Rash 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Rash generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Rash macular 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Rash maculo-papular 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Rash pruritic 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Rash pustular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Rash vesicular 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Red blood cell count decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Red blood cell sedimentation rate increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Renal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Renal impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Renal tubular necrosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Respiratory disorder 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Respiratory distress 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Respiratory failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Respiratory tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Restless legs syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Rhabdomyolysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Rheumatoid arthritis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Rhinorrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Sciatica 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Shock haemorrhagic 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Sinus congestion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Sinus disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Sinusitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Skin cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Skin discolouration 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Skin disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Skin exfoliation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Skin hyperpigmentation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Skin mass 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Skin necrosis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Methotrexate Skin reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Skin ulcer 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Sleep disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Speech disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Spinal fracture 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Staphylococcal infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Stevens-Johnson syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Stomatitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Stress 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Subarachnoid haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Subdural haematoma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Suicide attempt 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Swelling 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Swelling face 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Swollen tongue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Systemic lupus erythematosus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Tachypnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Tenderness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Tendon rupture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Throat irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Thrombocytopenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Thrombocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Thrombophlebitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Tongue disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Tooth abscess 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Tooth disorder 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate Toothache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Toxic epidermal necrolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Toxic skin eruption 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Transaminases increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Transient ischaemic attack 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Treatment failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Tumour lysis syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Ulcer 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Unevaluable event 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Unresponsive to stimuli 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Upper gastrointestinal haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Upper respiratory tract infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Urinary incontinence 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Methotrexate Urinary retention 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Methotrexate Urinary tract disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Urosepsis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Vision blurred 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate Weight decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate White blood cell count decreased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Methotrexate White blood cell count increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate sodium Abdominal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate sodium Agranulocytosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate sodium Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate sodium Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate sodium Aphasia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Methotrexate sodium Aplastic anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate sodium Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate sodium Bone marrow failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate sodium Chronic obstructive pulmonary disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate sodium Cognitive disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate sodium Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate sodium Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methotrexate sodium Deep vein thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate sodium Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate sodium Diarrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate sodium Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate sodium Dysarthria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate sodium Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate sodium Encephalopathy 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Methotrexate sodium Epistaxis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate sodium Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate sodium Furuncle 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate sodium Gastrointestinal disorder 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate sodium Headache 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate sodium Hemiparesis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate sodium Hepatic cirrhosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate sodium Hepatic enzyme increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate sodium Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate sodium Hepatotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate sodium Herpes zoster 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate sodium Hyperhidrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate sodium Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate sodium Infection 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate sodium Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Methotrexate sodium Liver function test increased 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate sodium Lymphadenopathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate sodium Lymphoma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate sodium Malaise 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate sodium Melaena 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methotrexate sodium Mood altered 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate sodium Mouth ulceration 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate sodium Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate sodium Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate sodium Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate sodium Osteonecrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate sodium Osteoporosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate sodium Pancytopenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate sodium Pericarditis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate sodium Photosensitivity reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate sodium Pneumocystis jirovecii pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate sodium Pneumonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate sodium Proteinuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate sodium Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate sodium Pulmonary embolism 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate sodium Pulmonary fibrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate sodium Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Methotrexate sodium Rash 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methotrexate sodium Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate sodium Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate sodium Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate sodium Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate sodium Skin necrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate sodium Stevens-Johnson syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methotrexate sodium Stomatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate sodium Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methotrexate sodium Thrombophlebitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methotrexate sodium Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methotrexate sodium Toxic epidermal necrolysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methotrexate sodium Tumour lysis syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methotrexate sodium Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Methotrexate sodium Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methotrexate sodium Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Methoxsalen Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methoxsalen Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methoxsalen Hypotension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methoxsalen Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methoxsalen Pulmonary embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methoxsalen Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methyldopa Acute hepatic failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methyldopa Atrial septal defect 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Methyldopa Drug-induced liver injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methyldopa Foetal growth restriction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methyldopa Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Methyldopa Premature delivery 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylene blue Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylene blue Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylene blue Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylene blue Serotonin syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Methylphenidate Acute myocardial infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylphenidate Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylphenidate Anger 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylphenidate Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methylphenidate Apathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylphenidate Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methylphenidate Blood creatine phosphokinase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylphenidate Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylphenidate Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methylphenidate Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylphenidate Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methylphenidate Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylphenidate Crying 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylphenidate Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methylphenidate Depressed mood 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylphenidate Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Methylphenidate Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Methylphenidate Dizziness 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Methylphenidate Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methylphenidate Drug dependence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylphenidate Drug interaction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylphenidate Dyskinesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylphenidate Emotional disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylphenidate Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methylphenidate Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methylphenidate Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylphenidate Headache 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Methylphenidate Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylphenidate Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylphenidate Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylphenidate Insomnia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Methylphenidate Irritability 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methylphenidate Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methylphenidate Mood swings 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylphenidate Muscle spasms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylphenidate Mydriasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylphenidate Myocarditis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylphenidate Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylphenidate Nervousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylphenidate Palpitations 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methylphenidate Paranoia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylphenidate Psychomotor hyperactivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylphenidate Psychotic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylphenidate Pulmonary congestion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methylphenidate Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylphenidate Restlessness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylphenidate Sleep disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylphenidate Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylphenidate Status epilepticus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylphenidate Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylphenidate Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylphenidate Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylphenidate Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylphenidate Tachypnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylphenidate Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylphenidate Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylphenidate Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylphenidate hydrochloride Aggression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylphenidate hydrochloride Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylphenidate hydrochloride Anger 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Methylphenidate hydrochloride Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Methylphenidate hydrochloride Arrhythmia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylphenidate hydrochloride Arthralgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Methylphenidate hydrochloride Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylphenidate hydrochloride Cerebral haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylphenidate hydrochloride Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methylphenidate hydrochloride Decreased appetite 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylphenidate hydrochloride Depressed mood 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylphenidate hydrochloride Depression 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Methylphenidate hydrochloride Dyskinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylphenidate hydrochloride Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methylphenidate hydrochloride Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methylphenidate hydrochloride Heart rate increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylphenidate hydrochloride Lethargy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methylphenidate hydrochloride Nervousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylphenidate hydrochloride Neuroleptic malignant syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylphenidate hydrochloride Peripheral coldness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylphenidate hydrochloride Psychomotor hyperactivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylphenidate hydrochloride Psychotic disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Methylphenidate hydrochloride Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylphenidate hydrochloride Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylphenidate hydrochloride Somnolence 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Methylphenidate hydrochloride Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methylphenidate hydrochloride Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylphenidate hydrochloride Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylphenidate hydrochloride Weight decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methylprednisolone Abdominal distension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Abdominal pain 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Acne 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylprednisolone Acute kidney injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methylprednisolone Aphasia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methylprednisolone Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methylprednisolone Atrial fibrillation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methylprednisolone Bacterial infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Blindness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Methylprednisolone Bradycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone C-reactive protein increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylprednisolone Cerebral infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Cerebrovascular accident 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Chest discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylprednisolone Coagulopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Cognitive disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Confusional state 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Decreased appetite 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Delirium 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Methylprednisolone Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylprednisolone Disturbance in attention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylprednisolone Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methylprednisolone Drug dependence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylprednisolone Drug reaction with eosinophilia and systemic symptoms 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylprednisolone Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylprednisolone Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylprednisolone Flushing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Fungal infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methylprednisolone Gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Hepatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Hepatocellular injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylprednisolone Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylprednisolone Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methylprednisolone Hypokalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Immune thrombocytopenic purpura 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylprednisolone Infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Influenza 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methylprednisolone Interstitial lung disease 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Intracranial pressure increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Intraocular pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylprednisolone Jaundice 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Joint swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylprednisolone Leukocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Leukopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Loss of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Lung disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Lung infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Lymphadenopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylprednisolone Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Melaena 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Metabolic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Musculoskeletal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylprednisolone Musculoskeletal stiffness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylprednisolone Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methylprednisolone Myopathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methylprednisolone Nervous system disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Obesity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylprednisolone Oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylprednisolone Optic neuritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylprednisolone Osteonecrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methylprednisolone Osteoporosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylprednisolone Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methylprednisolone Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methylprednisolone Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Paraesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Methylprednisolone Pericardial effusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Peritonitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Petechiae 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Pleural effusion 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Pneumocystis jirovecii pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylprednisolone Pulmonary embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Methylprednisolone Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Renal impairment 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Rheumatoid arthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylprednisolone Seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Skin discolouration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylprednisolone Skin exfoliation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Skin ulcer 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methylprednisolone Staphylococcal infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Swelling face 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Throat tightness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylprednisolone Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Transaminases increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Troponin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Methylprednisolone Upper gastrointestinal haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Urinary incontinence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methylprednisolone Urinary retention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylprednisolone Urinary tract infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylprednisolone Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methylprednisolone Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Methylprednisolone Weight decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone Weight increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone acetate Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methylprednisolone acetate Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methylprednisolone acetate Arthropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylprednisolone acetate Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methylprednisolone acetate Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone acetate Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methylprednisolone acetate Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methylprednisolone acetate Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylprednisolone acetate Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylprednisolone sodium succinate Abdominal distension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylprednisolone sodium succinate Acne 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylprednisolone sodium succinate Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone sodium succinate Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone sodium succinate Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Methylprednisolone sodium succinate Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone sodium succinate Circulatory collapse 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone sodium succinate Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylprednisolone sodium succinate Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone sodium succinate Fluid retention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylprednisolone sodium succinate Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylprednisolone sodium succinate Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone sodium succinate Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone sodium succinate Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Methylprednisolone sodium succinate Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylprednisolone sodium succinate Intraocular pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylprednisolone sodium succinate Muscular weakness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylprednisolone sodium succinate Osteonecrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methylprednisolone sodium succinate Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Methylprednisolone sodium succinate Rash 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Methylprednisolone sodium succinate Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Methylprednisolone sodium succinate Vertigo 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Methylprednisolone sodium succinate Weight increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoclopramide Acute hepatic failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoclopramide Acute kidney injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoclopramide Acute respiratory distress syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoclopramide Akathisia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metoclopramide Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoclopramide Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metoclopramide Ataxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoclopramide Atrial septal defect 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Metoclopramide Cardiac arrest 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoclopramide Cardio-respiratory arrest 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoclopramide Cardiogenic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoclopramide Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoclopramide Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Metoclopramide Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Metoclopramide Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Metoclopramide Diarrhoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoclopramide Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoclopramide Dyskinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metoclopramide Dyspnoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metoclopramide Dystonia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metoclopramide Extrapyramidal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metoclopramide Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metoclopramide Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoclopramide Hypoxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoclopramide Metabolic acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoclopramide Movement disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metoclopramide Multiple organ dysfunction syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoclopramide Musculoskeletal stiffness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metoclopramide Nervous system disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metoclopramide Neuroleptic malignant syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoclopramide Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Metoclopramide Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoclopramide Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoclopramide Serotonin syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoclopramide Speech disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metoclopramide Suicidal ideation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Metoclopramide Tardive dyskinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metoclopramide Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metoclopramide Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoclopramide hydrochloride Akathisia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metoclopramide hydrochloride Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Metoclopramide hydrochloride Dyskinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metoclopramide hydrochloride Dyspnoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoclopramide hydrochloride Dystonia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metoclopramide hydrochloride Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoclopramide hydrochloride Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metoclopramide hydrochloride Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoclopramide hydrochloride Seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metoclopramide hydrochloride Tardive dyskinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metoclopramide hydrochloride Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metolazone Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metolazone Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metolazone Blood urea increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metolazone Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metolazone Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metolazone Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metolazone Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metolazone Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metolazone Hypovolaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metolazone Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metolazone Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Abdominal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Abdominal pain upper 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metoprolol Abscess 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Acute myocardial infarction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Acute respiratory failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metoprolol Altered state of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Amnesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Angina pectoris 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Anuria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Apnoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Arrhythmia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Asthenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Atrial fibrillation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Atrial flutter 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Atrial septal defect 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Metoprolol Atrioventricular block 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Atrioventricular block complete 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Atrioventricular block first degree 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Bacterial infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Balance disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Basal cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metoprolol Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Blood potassium increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Blood pressure decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Bradycardia 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Metoprolol Brain oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Bronchospasm 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Cardiac disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Cardiac failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Cardiac failure acute 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Cardiogenic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metoprolol Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Cerebral infarction 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Metoprolol Chest discomfort 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Chest pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Circulatory collapse 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Coagulopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Cold sweat 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Confusional state 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Crying 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Cyanosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Decreased appetite 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Deep vein thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Delusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Depressed level of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Dermatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Diarrhoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Disorientation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Disturbance in attention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metoprolol Dizziness 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Metoprolol Drug abuse 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metoprolol Drug-induced liver injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metoprolol Dyspnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Dyspnoea exertional 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Ejection fraction decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Encephalopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Enteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Epilepsy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metoprolol Erythema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Fatigue 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Flushing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Foetal growth restriction 0.0 0.0 0.0 0.0 1.0 0.0 1.0 Metoprolol Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Gastrointestinal haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Generalised oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Haematochezia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Haemodynamic instability 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Haemoglobin decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Haemorrhage intracranial 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Heart rate irregular 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Metoprolol Hepatic failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Hepatic necrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Hepatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Hepatotoxicity 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Hot flush 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Hyperglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Metoprolol Hyperkalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Hypertension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Hyperventilation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Hypoacusis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Hypocalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Hypoglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Hypokinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Hypomagnesaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Hypotension 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Metoprolol Hypoxia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Intentional self-injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Jaundice 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Lactic acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Liver function test increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Loss of consciousness 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Maternal drugs affecting foetus 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Metoprolol Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Metabolic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Muscular weakness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Musculoskeletal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Nausea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Necrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Nervousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metoprolol Nightmare 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metoprolol Ocular hyperaemia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metoprolol Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Oliguria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Oxygen saturation decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Pallor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Palpitations 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Paranoia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metoprolol Peripheral coldness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Pleural effusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Pneumonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 1.0 Metoprolol Premature delivery 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metoprolol Presyncope 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Proteinuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metoprolol Psychotic disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Pulmonary embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Pulmonary oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Rash papular 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Rash pruritic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metoprolol Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Renal impairment 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Respiratory depression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Respiratory distress 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metoprolol Respiratory failure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Restlessness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Retching 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Sensory disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Sepsis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Sinus bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Skin exfoliation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metoprolol Skin ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Small intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Somnolence 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Subarachnoid haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Suicide attempt 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Swelling face 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metoprolol Swollen tongue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Syncope 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Tachypnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Tension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metoprolol Tinnitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metoprolol Torsade de pointes 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Transient ischaemic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Troponin increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Vaginal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Ventricular arrhythmia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Ventricular extrasystoles 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Ventricular fibrillation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Weight decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol Weight increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol succinate Alopecia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol succinate Anxiety 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol succinate Bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol succinate Cerebrovascular accident 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metoprolol succinate Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol succinate Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol succinate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Metoprolol succinate Depressed level of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol succinate Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol succinate Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metoprolol succinate Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol succinate Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metoprolol succinate Palpitations 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metoprolol succinate Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metoprolol succinate Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol succinate Syncope 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol succinate Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol tartrate Atrioventricular block 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Metoprolol tartrate Atrioventricular block complete 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol tartrate Bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol tartrate Cardiac failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol tartrate Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol tartrate Confusional state 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol tartrate Depressed level of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Metoprolol tartrate Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metoprolol tartrate Dizziness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol tartrate Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol tartrate Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol tartrate Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metoprolol tartrate Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metoprolol tartrate Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Abasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Abdominal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Abdominal distension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Abdominal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Abdominal pain upper 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Metronidazole Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Acute generalised exanthematous pustulosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Acute hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Acute kidney injury 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Acute myocardial infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Agitation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Agranulocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Altered state of consciousness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Angioedema 0.0 0.0 0.0 0.0 0.0 1.0 1.0 Metronidazole Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Aphasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Aphthous ulcer 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Aplastic anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Metronidazole Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Balance disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Blindness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Blister 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Blood alkaline phosphatase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Blood bilirubin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Blood creatinine increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Blood glucose increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Bone pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Bradycardia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Burning sensation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole C-reactive protein increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Cardiac disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Cellulitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Chills 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Chromaturia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Metronidazole Circulatory collapse 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Clostridium difficile colitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Coagulopathy 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Cognitive disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Constipation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Contusion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Coordination abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Crying 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Metronidazole Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Depressed level of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Depressed mood 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Dermatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Dermatitis allergic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Dermatitis exfoliative 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Diplopia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Disease recurrence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Disorientation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Metronidazole Drug hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Metronidazole Drug intolerance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Drug resistance 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Drug-induced liver injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Dry skin 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Dysaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Dysarthria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Dysgeusia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Metronidazole Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Dysphagia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Dysphonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Dyspnoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Dystonia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Ear disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Encephalopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Erythema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Eye pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Failure to thrive 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Metronidazole Fear 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Metronidazole Feeling cold 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Feeling hot 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Flatulence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Fungal infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Gamma-glutamyltransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Gastroenteritis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Gastrooesophageal reflux disease 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Generalised tonic-clonic seizure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Haematochezia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Haemoglobin decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Hallucination 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Headache 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Metronidazole Heart rate increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Hemiparesis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Hot flush 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Hyperhidrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Hypersensitivity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Hypoacusis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Hypoxia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Infection 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Influenza like illness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Irritability 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Lethargy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Limb discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Lip swelling 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Metronidazole Loss of consciousness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Malaise 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Metronidazole Melaena 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Mental impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Metabolic acidosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Migraine 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Mobility decreased 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Mood altered 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Mouth ulceration 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Musculoskeletal stiffness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Metronidazole Nasal congestion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Nausea 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Metronidazole Neck pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Nervous system disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Neuritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Night sweats 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Nightmare 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Oedema peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Oral candidiasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Oral pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Palpitations 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Pancytopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Metronidazole Paraesthesia oral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Paranoia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Parkinson's disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Parkinsonism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Metronidazole Peritonitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Pharyngeal oedema 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Photophobia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Polyneuropathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Premature baby 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Pruritus generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Pseudomembranous colitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Pulmonary embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Pyrexia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Rash macular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Rash maculo-papular 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Rash papular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Rash pruritic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Rash vesicular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Seizure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Sensory disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Skin burning sensation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Skin lesion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Skin reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Somnolence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Speech disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Status epilepticus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Suicidal ideation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Suicide attempt 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Swelling 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Swelling face 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Metronidazole Syncope 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Tendonitis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Thinking abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Throat tightness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Tinnitus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Tongue discolouration 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Torsade de pointes 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Toxic epidermal necrolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Metronidazole Transaminases increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Treatment failure 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Metronidazole Urticaria 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Metronidazole Vaginal discharge 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Metronidazole Vertigo 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole Vomiting 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Metronidazole White blood cell count increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metyrapone Cellulitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metyrapone Deep vein thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metyrapone Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Metyrapone Pulmonary embolism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Micafungin Candida infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Micafungin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Micafungin Diarrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Micafungin Dyspnoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Micafungin Hypokalaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Micafungin Hypotension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Micafungin Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Micafungin Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Micafungin Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Micafungin Pyrexia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Micafungin Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Micafungin Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Micafungin Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Micafungin Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Micafungin Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Micafungin Treatment failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Micafungin Vomiting 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Micafungin sodium Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Micafungin sodium Insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Micafungin sodium Renal failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Micafungin sodium Toxic epidermal necrolysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Midazolam Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Midazolam Hypotension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Midazolam Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Midazolam hydrochloride Aggression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Midazolam hydrochloride Bradycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Midazolam hydrochloride Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Midazolam hydrochloride Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Midostaurin Abdominal pain 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Midostaurin Acute myeloid leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Midostaurin Anaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Midostaurin Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Midostaurin Bone marrow failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Midostaurin Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Midostaurin Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Midostaurin Colitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Midostaurin Cough 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Midostaurin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Midostaurin Diarrhoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Midostaurin Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Midostaurin Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Midostaurin Dyspnoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Midostaurin Electrocardiogram QT prolonged 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Midostaurin Fatigue 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Midostaurin Febrile neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Midostaurin Feeding disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Midostaurin Gastrointestinal haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Midostaurin Haemoglobin decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Midostaurin Headache 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Midostaurin Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Midostaurin Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Midostaurin Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Midostaurin Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Midostaurin Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Midostaurin Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Midostaurin Mucosal inflammation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Midostaurin Nausea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Midostaurin Neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Midostaurin Pancytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Midostaurin Platelet count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Midostaurin Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Midostaurin Pulmonary oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Midostaurin Pyrexia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Midostaurin Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Midostaurin Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Midostaurin Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Midostaurin Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Midostaurin Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Midostaurin Vomiting 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mifepristone Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mifepristone Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mifepristone Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mifepristone Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mifepristone Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mifepristone Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mifepristone Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mifepristone Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mifepristone Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mifepristone Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mifepristone Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mifepristone Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mifepristone Fluid overload 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mifepristone Haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mifepristone Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mifepristone Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mifepristone Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mifepristone Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mifepristone Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mifepristone Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mifepristone Muscle spasms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mifepristone Nasopharyngitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mifepristone Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mifepristone Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mifepristone Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mifepristone Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mifepristone Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mifepristone Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mifepristone Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mifepristone Vaginal haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mifepristone Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Miglustat Aggression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Miglustat Amnesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Miglustat Aphasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Miglustat Aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Miglustat Ataxia 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Miglustat Bronchitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Miglustat Choking 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Miglustat Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Miglustat Cough 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Miglustat Crying 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Miglustat Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Miglustat Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Miglustat Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Miglustat Diarrhoea 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Miglustat Disease progression 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Miglustat Drug intolerance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Miglustat Dysphagia 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Miglustat Dyspnoea 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Miglustat Dystonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Miglustat Epilepsy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Miglustat Epistaxis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Miglustat Eye swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Miglustat Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Miglustat Feeding disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Miglustat Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Miglustat Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Miglustat Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Miglustat Haematochezia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Miglustat Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Miglustat Hypoxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Miglustat Influenza 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Miglustat Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Miglustat Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Miglustat Lacrimation increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Miglustat Malnutrition 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Miglustat Oxygen saturation decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Miglustat Pallor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Miglustat Platelet count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Miglustat Pneumonia 1.0 1.0 1.0 1.0 0.0 0.0 0.0 Miglustat Pneumonia aspiration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Miglustat Productive cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Miglustat Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Miglustat Rash 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Miglustat Respiratory disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Miglustat Respiratory distress 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Miglustat Respiratory failure 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Miglustat Respiratory tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Miglustat Salivary hypersecretion 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Miglustat Seizure 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Miglustat Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Miglustat Sneezing 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Miglustat Somnolence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Miglustat Speech disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Miglustat Thrombocytopenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Miglustat Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Miglustat Upper respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Miglustat Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Miglustat Vomiting 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Miglustat Weight decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Miglustat Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Milnacipran hydrochloride Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Milnacipran hydrochloride Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Minocycline hydrochloride Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Minocycline hydrochloride Anaphylactic reaction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Minocycline hydrochloride Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Minocycline hydrochloride Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Minocycline hydrochloride Headache 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Minocycline hydrochloride Photosensitivity reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Minocycline hydrochloride Skin hyperpigmentation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Minocycline hydrochloride Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Minocycline hydrochloride Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Minoxidil Alopecia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Minoxidil Angina pectoris 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Minoxidil Blood pressure decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Minoxidil Cardiac disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Minoxidil Cardiac tamponade 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Minoxidil Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Minoxidil Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Minoxidil Drug hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Minoxidil Dyspnoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Minoxidil Erythema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Minoxidil Eye irritation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Minoxidil Eye swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Minoxidil Fluid overload 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Minoxidil Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Minoxidil Hypersensitivity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Minoxidil Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Minoxidil Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Minoxidil Palpitations 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Minoxidil Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Minoxidil Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Minoxidil Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Minoxidil Skin burning sensation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Minoxidil Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirabegron Abdominal distension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirabegron Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirabegron Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Arrhythmia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Mirabegron Back pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Balance disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirabegron Blood glucose increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Blood pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirabegron Chromaturia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Confusional state 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Constipation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Cough 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirabegron Cystitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mirabegron Delirium 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Dementia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirabegron Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirabegron Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Drug hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Dry eye 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Mirabegron Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirabegron Dysuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Eyelid oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Mirabegron Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Mirabegron Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirabegron Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Haematuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Headache 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Mirabegron Heart rate increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirabegron Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Hypertensive crisis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Hypoaesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Ileus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirabegron Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Mirabegron Joint swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Lip swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Malaise 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Mirabegron Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirabegron Micturition urgency 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Muscle spasms 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirabegron Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Nasal congestion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Nasopharyngitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Nervous system disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirabegron Nocturia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Oropharyngeal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirabegron Pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Mirabegron Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirabegron Palpitations 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Mirabegron Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirabegron Parkinson's disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Mirabegron Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirabegron Pollakiuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Prostate cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Mirabegron Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirabegron Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Rash generalised 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Rhinorrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Sinusitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Sleep apnoea syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Sleep disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Urinary incontinence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Urinary retention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Urinary tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirabegron Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirtazapine Abasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Abdominal distension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Abdominal pain upper 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Abnormal dreams 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirtazapine Acute hepatic failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Affect lability 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Ageusia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Aggression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Agitation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Akathisia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Altered state of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Amnesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Anger 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Mirtazapine Anuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Apathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Aphasia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Aplastic anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Arthralgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Arthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Asphyxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Atrial fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Atrial septal defect 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Mirtazapine Atrioventricular block 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Balance disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Blood bilirubin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Blood creatine phosphokinase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Blood disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirtazapine Blood potassium increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Blood pressure decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Blood triglycerides increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Bone marrow failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Bone pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirtazapine Bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Brain oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Burning sensation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Cerebrovascular accident 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Chest pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Chromaturia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Circulatory collapse 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Cognitive disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Coma 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Confusional state 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Mirtazapine Contusion 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Coordination abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Crying 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Decreased appetite 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Delirium 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Delusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Dementia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Depersonalisation/derealisation disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Depressed level of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Depression 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Diabetes mellitus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Diabetic ketoacidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Diplopia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirtazapine Disorientation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Disturbance in attention 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Drug abuse 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Drug dependence 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Mirtazapine Drug intolerance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Drug reaction with eosinophilia and systemic symptoms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Drug withdrawal syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Drug-induced liver injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Dry eye 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Dry skin 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Dysarthria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Dysgeusia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Dyskinesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Dysphagia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Dysphoria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirtazapine Dyspnoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Dysstasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Dystonia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Eating disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Emotional distress 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Epilepsy 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Mirtazapine Erectile dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Euphoric mood 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Extrapyramidal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Eye pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Face oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Fear 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Feeling abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Feeling jittery 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Gait disturbance 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Gastritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirtazapine Gastrointestinal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Gastrooesophageal reflux disease 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Generalised oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Generalised tonic-clonic seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Haematemesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Hallucination 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Hallucination, visual 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Heart rate increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Hepatic cirrhosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Hepatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Hepatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Hepatotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirtazapine Hyperaesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirtazapine Hyperbilirubinaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Hyperglycaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirtazapine Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Hyperkalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Hypersensitivity 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Hypertension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Hypertonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Hypoaesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Hypoaesthesia oral 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Hypoglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Hypokinesia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Hypothermia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Hypothyroidism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Hypotonia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Inappropriate antidiuretic hormone secretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Increased appetite 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Insomnia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Intentional self-injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Intestinal obstruction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Irritability 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Mirtazapine Jaundice 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Joint swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Laryngeal oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Lethargy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Libido decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Liver disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Local swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Lung disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirtazapine Malaise 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Mania 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Maternal drugs affecting foetus 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Mirtazapine Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Menorrhagia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Mental disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Mental impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirtazapine Micturition urgency 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Miosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Mood swings 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Mouth ulceration 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Movement disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Muscle rigidity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Muscle spasms 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Muscle twitching 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Muscular weakness 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Mirtazapine Musculoskeletal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Musculoskeletal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Musculoskeletal stiffness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Mydriasis 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Mirtazapine Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Myoclonus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Neck pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Nervous system disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Nervousness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Mirtazapine Neuroleptic malignant syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Night sweats 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Mirtazapine Nightmare 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Oedema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Oral discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Oropharyngeal pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Oxygen saturation decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Pallor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Palpitations 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Pancreatitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Pancytopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Panic attack 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Paraesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Paralysis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Paranoia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Parkinsonism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Parosmia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Personality change 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Petechiae 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Pharyngeal oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Photosensitivity reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirtazapine Platelet count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Pneumonia aspiration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Pollakiuria 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Polyneuropathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Premature baby 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Mirtazapine Priapism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Pruritus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Psychomotor hyperactivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Psychotic disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Pulmonary embolism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Pyrexia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Rash pruritic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirtazapine Red blood cell sedimentation rate increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Respiratory disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Respiratory distress 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Restless legs syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Restlessness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Sedation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Seizure 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Sensory disturbance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirtazapine Sensory loss 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Serotonin syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Sexual dysfunction 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Sinus tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Skin burning sensation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Skin disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Sleep apnoea syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Sleep disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Somnolence 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Sopor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Speech disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Stevens-Johnson syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Stress 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Suicidal ideation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Suicide attempt 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Swelling face 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Swollen tongue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Syncope 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Tachycardia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Mirtazapine Tardive dyskinesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Thinking abnormal 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Mirtazapine Thirst 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirtazapine Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Tinnitus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Torsade de pointes 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Treatment failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Tremor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Unresponsive to stimuli 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Urinary incontinence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Urinary retention 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Urinary tract infection 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Ventricular fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mirtazapine Vertigo 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Vision blurred 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Visual impairment 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Vomiting 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Weight decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mirtazapine Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Mirtazapine Wheezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mirtazapine White blood cell count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mirtazapine Withdrawal syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Misoprostol Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Misoprostol Cardiac arrest 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Misoprostol Cerebrovascular accident 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Misoprostol Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Misoprostol Chills 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Misoprostol Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Misoprostol Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Misoprostol Foetal death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Misoprostol Foetal growth restriction 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Misoprostol Haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Misoprostol Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Misoprostol Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Misoprostol Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Misoprostol Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Misoprostol Metrorrhagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Misoprostol Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Misoprostol Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Misoprostol Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Misoprostol Pulmonary embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Misoprostol Pyrexia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Misoprostol Shock haemorrhagic 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Misoprostol Tremor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Misoprostol Urticaria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Misoprostol Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mitomycin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mitomycin Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mitomycin Neutropenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mitomycin Pancytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mitomycin Visual acuity reduced 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mitomycin Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mitotane Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mitotane Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mitoxantrone hydrochloride Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mitoxantrone hydrochloride Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mitoxantrone hydrochloride Febrile neutropenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mitoxantrone hydrochloride Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mitoxantrone hydrochloride Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mitoxantrone hydrochloride Malaise 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mitoxantrone hydrochloride Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mitoxantrone hydrochloride Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mitoxantrone hydrochloride Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mitoxantrone hydrochloride Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Modafinil Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Modafinil Aggression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Modafinil Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Modafinil Cognitive disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Modafinil Confusional state 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Modafinil Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Modafinil Depressed mood 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Modafinil Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Modafinil Diarrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Modafinil Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Modafinil Disturbance in attention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Modafinil Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Modafinil Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Modafinil Drug reaction with eosinophilia and systemic symptoms 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Modafinil Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Modafinil Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Modafinil Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Modafinil Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Modafinil Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Modafinil Renal impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Modafinil Somnolence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Modafinil Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mometasone Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mometasone Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Ageusia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Blister 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mometasone furoate Burning sensation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Chest pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Chills 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Cough 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mometasone furoate Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Dermatitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Diarrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mometasone furoate Dry skin 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Dyspnoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Eczema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Epistaxis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Erythema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Eye pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Eye swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Feeling abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mometasone furoate Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mometasone furoate Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Hypertension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Lymphadenopathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Malaise 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mometasone furoate Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Nausea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Neuralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Oropharyngeal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mometasone furoate Osteonecrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Pain of skin 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mometasone furoate Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Pyrexia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Rash 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Rash erythematous 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Rhinorrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mometasone furoate Skin burning sensation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Skin discolouration 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Skin exfoliation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mometasone furoate Swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Swelling face 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mometasone furoate Throat irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mometasone furoate Tremor 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mometasone furoate Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mometasone furoate Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Montelukast sodium Abdominal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Montelukast sodium Abnormal dreams 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Montelukast sodium Aggression 0.0 1.0 0.0 1.0 0.0 1.0 1.0 Montelukast sodium Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Montelukast sodium Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Montelukast sodium Anxiety 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Montelukast sodium Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Montelukast sodium Aspartate aminotransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Montelukast sodium Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Montelukast sodium Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Montelukast sodium Contusion 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Montelukast sodium Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Montelukast sodium Depression 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Montelukast sodium Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Montelukast sodium Disorientation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Montelukast sodium Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Montelukast sodium Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Montelukast sodium Ear infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Montelukast sodium Eczema 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Montelukast sodium Epistaxis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Montelukast sodium Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Montelukast sodium Haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Montelukast sodium Hallucination 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Montelukast sodium Headache 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Montelukast sodium Hostility 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Montelukast sodium Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Montelukast sodium Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Montelukast sodium Insomnia 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Montelukast sodium Irritability 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Montelukast sodium Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Montelukast sodium Myalgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Montelukast sodium Nasal congestion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Montelukast sodium Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Montelukast sodium Palpitations 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Montelukast sodium Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Montelukast sodium Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Montelukast sodium Rash 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Montelukast sodium Restlessness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Montelukast sodium Seizure 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Montelukast sodium Sinusitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Montelukast sodium Somnolence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Montelukast sodium Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Montelukast sodium Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Montelukast sodium Vomiting 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Morphine Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Morphine Acute respiratory distress syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine Altered state of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine Apnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine Asphyxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Morphine Aspiration 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine Asthma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Morphine Atelectasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine Brain injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Morphine Brain oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine C-reactive protein increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Morphine Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Morphine Circulatory collapse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Morphine Coagulopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Morphine Confusional state 0.0 0.0 1.0 0.0 0.0 1.0 0.0 Morphine Constipation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Morphine Crying 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine Cyanosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Morphine Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine Depressed level of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine Discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Morphine Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Morphine Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Morphine Drug dependence 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Morphine Drug hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Morphine Drug interaction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Morphine Drug withdrawal syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine Dyspnoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine Emotional distress 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Morphine Encephalopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine Faecaloma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine Fear 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine Gait disturbance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Morphine Gastrooesophageal reflux disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine Generalised tonic-clonic seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine Hallucination, visual 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine Heart rate decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Morphine Hyperaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine Hyperthermia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Morphine Hypotension 1.0 1.0 0.0 0.0 0.0 1.0 0.0 Morphine Hypotonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine Hypoxia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Morphine Ileus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine Joint swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Morphine Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine Metabolic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine Miosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine Mydriasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine Neurotoxicity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine Oxygen saturation decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Morphine Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Morphine Posterior reversible encephalopathy syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Morphine Premature baby 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Morphine Premature delivery 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Morphine Pulmonary congestion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Morphine Pulmonary hypertension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Morphine Pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Morphine Renal failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine Respiratory depression 1.0 1.0 0.0 0.0 0.0 1.0 0.0 Morphine Respiratory disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine Respiratory distress 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine Respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine Rhabdomyolysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Morphine Sedation 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Morphine Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine Serotonin syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Morphine Shock 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine Sleep apnoea syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Morphine Somnolence 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Morphine Stress cardiomyopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine Swelling face 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Morphine Thrombocytopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Morphine Treatment failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Morphine Tremor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine Unresponsive to stimuli 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Morphine Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine Vomiting 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Morphine Withdrawal syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine sulfate Abdominal distension 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Morphine sulfate Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine sulfate Abdominal pain lower 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine sulfate Agitation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine sulfate Alanine aminotransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Morphine sulfate Anaphylactic reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Morphine sulfate Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Morphine sulfate Apnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine sulfate Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Morphine sulfate Asthenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Morphine sulfate Bradycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine sulfate Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine sulfate Chills 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Morphine sulfate Confusional state 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Morphine sulfate Constipation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Morphine sulfate Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Morphine sulfate Depressed level of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine sulfate Depression 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Morphine sulfate Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine sulfate Disorientation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Morphine sulfate Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Morphine sulfate Drug withdrawal syndrome 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Morphine sulfate Dyspnoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine sulfate Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Morphine sulfate Euphoric mood 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Morphine sulfate Feeling abnormal 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Morphine sulfate Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Morphine sulfate Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine sulfate Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine sulfate Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Morphine sulfate Intestinal obstruction 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Morphine sulfate Lethargy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine sulfate Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Morphine sulfate Mental impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Morphine sulfate Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine sulfate Miosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine sulfate Mood swings 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Morphine sulfate Muscle spasms 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Morphine sulfate Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Morphine sulfate Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine sulfate Palpitations 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine sulfate Pancreatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine sulfate Paraesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine sulfate Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Morphine sulfate Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Morphine sulfate Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine sulfate Respiratory depression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine sulfate Rhinorrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Morphine sulfate Sedation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Morphine sulfate Seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine sulfate Shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Morphine sulfate Somnolence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Morphine sulfate Stupor 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Morphine sulfate Syncope 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Morphine sulfate Tachycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine sulfate Thinking abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Morphine sulfate Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Morphine sulfate Urinary retention 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Morphine sulfate Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Morphine sulfate Vision blurred 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Morphine sulfate Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Morphine sulfate Vomiting 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Abdominal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Moxifloxacin Abdominal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin Abdominal pain upper 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Moxifloxacin Acute kidney injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Agitation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Amylase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Angina pectoris 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Moxifloxacin Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin Arrhythmia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Arthralgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin Aspartate aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Moxifloxacin Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin Asthma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Atrial fibrillation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Blood pressure increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Burning sensation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Cardiac failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Moxifloxacin Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Chills 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Confusional state 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Conjunctival hyperaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Moxifloxacin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Delirium 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Moxifloxacin Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin Diarrhoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Disorientation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin Drug hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Moxifloxacin Dyspepsia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Eye pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin Eye pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Moxifloxacin Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin Feeling abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Flatulence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Flushing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Moxifloxacin Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin Gastrooesophageal reflux disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Moxifloxacin Hallucination 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin Heart rate increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Hepatic enzyme increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Hepatic function abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Moxifloxacin Hepatic necrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Moxifloxacin Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Moxifloxacin Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin Myalgia 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin Neutropenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Moxifloxacin Ocular hyperaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Moxifloxacin Oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin Pancytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Psychotic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Moxifloxacin Pyrexia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Moxifloxacin Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Respiratory distress 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Stevens-Johnson syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Tendon rupture 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin Tendonitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin Thrombocytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin Torsade de pointes 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Toxic epidermal necrolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Tremor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Visual acuity reduced 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Moxifloxacin Visual impairment 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin Wheezing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Abdominal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Moxifloxacin hydrochloride Abdominal pain upper 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Agitation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Moxifloxacin hydrochloride Amnesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Anaphylactic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Moxifloxacin hydrochloride Arrhythmia 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Arthropathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Cardiovascular disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Moxifloxacin hydrochloride Chest discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Discomfort 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Moxifloxacin hydrochloride Disorientation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Moxifloxacin hydrochloride Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Dry eye 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Moxifloxacin hydrochloride Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Moxifloxacin hydrochloride Dyspnoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Eye irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Moxifloxacin hydrochloride Eye pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Eyelid oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Moxifloxacin hydrochloride Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Flatulence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Gastrointestinal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Moxifloxacin hydrochloride Hallucination 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Moxifloxacin hydrochloride Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Moxifloxacin hydrochloride Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Lacrimation increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Moxifloxacin hydrochloride Loss of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Mental disorder 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Moxifloxacin hydrochloride Migraine 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Moxifloxacin hydrochloride Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Muscle twitching 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Musculoskeletal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Nausea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Nervous system disorder 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Moxifloxacin hydrochloride Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Moxifloxacin hydrochloride Ocular hyperaemia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Moxifloxacin hydrochloride Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Palpitations 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Moxifloxacin hydrochloride Photophobia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Pruritus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Rash 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Skin disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Moxifloxacin hydrochloride Stevens-Johnson syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Suicidal ideation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Syncope 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Tendon rupture 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Tendonitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Torsade de pointes 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Toxic epidermal necrolysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Ventricular fibrillation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Vertigo 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Visual acuity reduced 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Moxifloxacin hydrochloride Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Moxifloxacin hydrochloride Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mupirocin Pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Abdominal discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Abdominal distension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Abdominal pain upper 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Abscess 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Acidosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Acne 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Acute coronary syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Acute hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Acute myeloid leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Acute myocardial infarction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Acute respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Agitation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Agranulocytosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Alopecia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Altered state of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Amnesia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Anaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Angioedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Anuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Apathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Aphasia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Aphthous ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Aplastic anaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Arrhythmia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Arthropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Aspartate aminotransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Asthenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Atelectasis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Atrial fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Atrial flutter 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Bacteraemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Bacterial infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Basal cell carcinoma 1.0 1.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mycophenolate mofetil Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Blood glucose increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Bone marrow failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Bronchitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil C-reactive protein increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Cachexia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Candida infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Cardiogenic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Cardiovascular disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Cellulitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Cerebral ischaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Cerebrovascular accident 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Chills 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Cholangitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Cholecystitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Cholestasis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Clostridium difficile colitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Clostridium difficile infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Coagulopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Colitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Coma 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Confusional state 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Cough 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Cyanosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Death 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Mycophenolate mofetil Decreased appetite 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Delirium 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Delusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Depressed level of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Dermatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Diabetes mellitus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Diarrhoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Diarrhoea haemorrhagic 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Diplopia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Disease recurrence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Disseminated intravascular coagulation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Drug dependence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Drug hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Drug-induced liver injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Dry eye 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Dysphonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Dyspnoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Encephalitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Encephalopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Enteritis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Epilepsy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Epistaxis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Eye disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Eye pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Facial paralysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Fatigue 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Fluid overload 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Fluid retention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Foetal growth restriction 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Mycophenolate mofetil Fungal infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Fungal skin infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Gait disturbance 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mycophenolate mofetil Gastric ulcer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Gastrointestinal disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Gastrooesophageal reflux disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Generalised oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Generalised tonic-clonic seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Gingivitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Haematochezia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Haematoma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Haemolysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Haemoptysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Headache 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Hemiparesis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Hemiplegia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Hepatic cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Hepatic cirrhosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Hepatic encephalopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Hepatic necrosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Hepatitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Hepatitis cholestatic 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Hepatocellular injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Hepatotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Herpes simplex 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Hydronephrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Hyperbilirubinaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Hypercalcaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Hypercholesterolaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Hyperglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Hyperkalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Hypoaesthesia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Hyponatraemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Hypothyroidism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Hypovolaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Hypoxia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Ileus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Ill-defined disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Inflammation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Influenza 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Interstitial lung disease 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Intestinal obstruction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Intestinal perforation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Jaundice 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Lactic acidosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Large intestine perforation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Lethargy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Leukocytosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Leukopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Liver disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Liver function test abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Loss of consciousness 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Lung disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Lung infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Lymphadenopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Lymphoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Lymphopenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Malaise 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Malignant melanoma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Malnutrition 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mycophenolate mofetil Melaena 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Meningitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Mental status changes 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Metabolic acidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Micturition urgency 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Mood altered 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Motor dysfunction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Mouth ulceration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Mucosal inflammation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Muscular weakness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Myalgia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Myocarditis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Myositis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Nausea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Neoplasm 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Nephropathy toxic 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Nephrotic syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Nervous system disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mycophenolate mofetil Neurotoxicity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Nystagmus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Obesity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Oesophageal ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Oesophagitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Oliguria 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Osteonecrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Osteoporosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mycophenolate mofetil Pancreatitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Pancreatitis acute 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Mycophenolate mofetil Pericardial effusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Peritonitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Pleural effusion 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Pneumocystis jirovecii pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Pneumonia bacterial 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Pneumothorax 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Pollakiuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Posterior reversible encephalopathy syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Mycophenolate mofetil Productive cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Proteinuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Psychotic disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Pulmonary alveolar haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Pulmonary embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Pulmonary fibrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Pulmonary haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Pulmonary hypertension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Pulmonary mass 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Purpura 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Pyelonephritis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Pyrexia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Rash 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Rash maculo-papular 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Renal impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Renal tubular necrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Respiratory disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Respiratory distress 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Respiratory tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Rhabdomyolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Rhinorrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Sinus tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Skin cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Skin exfoliation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Skin lesion 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Skin ulcer 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Somnolence 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Speech disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Splenomegaly 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Squamous cell carcinoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Staphylococcal infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Status epilepticus 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Stomatitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Syncope 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Mycophenolate mofetil Systemic lupus erythematosus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Tachycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Tachypnoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Thinking abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Thrombocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Thrombotic thrombocytopenic purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Transaminases increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Treatment failure 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Mycophenolate mofetil Ulcer 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Upper respiratory tract infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Urinary incontinence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Urinary tract infection 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Vertigo 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Viral infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Weight decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolate mofetil Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolic acid Abdominal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Abscess 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Acne 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Agranulocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Alopecia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Amnesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Anaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Aphthous ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Atelectasis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Atrial fibrillation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Bacterial infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Basal cell carcinoma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Blindness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Bone marrow failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid C-reactive protein increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Candida infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Cardiac disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Cerebrovascular accident 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Cholestasis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Coagulopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Colitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Diarrhoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Disease recurrence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolic acid Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Encephalopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Fluid overload 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Fungal infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Fungal skin infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Gastrointestinal haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Headache 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Herpes zoster 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Hyperglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Hyperkalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Hypocalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Hypokalaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Hyponatraemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Ill-defined disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Infection 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Interstitial lung disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Leukocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Liver function test abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Localised infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Loss of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Lung infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Lymphopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Malignant melanoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolic acid Melaena 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Memory impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Meningitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Mental disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Myocardial infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Nephropathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Nephrotic syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolic acid Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Mycophenolic acid Oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Oral candidiasis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Pericardial effusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Peripheral swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolic acid Peritonitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Platelet count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Mycophenolic acid Pleural effusion 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Pneumothorax 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Pulmonary fibrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Pyelonephritis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Rash 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Renal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Renal impairment 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Renal tubular necrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Respiratory distress 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Respiratory tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Seizure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Staphylococcal infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Tremor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Mycophenolic acid Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Mycophenolic acid Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nadolol Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naldemedine Abdominal pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Naldemedine Colon cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Naldemedine Diarrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Naldemedine Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Naldemedine Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Naldemedine Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Naldemedine Pancreatic carcinoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Naloxegol oxalate Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naloxegol oxalate Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naloxegol oxalate Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naloxone Pulmonary oedema 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Naloxone hydrochloride Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Naloxone hydrochloride Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Naloxone hydrochloride Seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naloxone hydrochloride Vomiting 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naltrexone Abdominal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Naltrexone Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Cardiac disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Chronic obstructive pulmonary disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Naltrexone Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Depression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Disturbance in attention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Drug dependence 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Drug withdrawal syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Dry mouth 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Epistaxis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Euphoric mood 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Feeling abnormal 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Naltrexone Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Hepatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Ill-defined disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Loss of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Lymphadenopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Mental disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Muscle twitching 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Naltrexone Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Nervousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Nightmare 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Naltrexone Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Panic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Poor quality sleep 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Pregnancy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naltrexone Psychotic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Pulmonary embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Sluggishness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Suicidal ideation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Suicide attempt 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Toothache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naltrexone Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone White blood cell count increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naltrexone Withdrawal syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Abdominal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naproxen Abdominal distension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Naproxen Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Naproxen Abdominal pain upper 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Naproxen Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Naproxen Acute myocardial infarction 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Naproxen Agranulocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Amnesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naproxen Anaemia 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Naproxen Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen Angina pectoris 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Naproxen Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Naproxen Arthropathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Naproxen Asthma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naproxen Atrial fibrillation 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Naproxen Back pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Blood urea increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Naproxen Cardiac disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Cerebral haemorrhage 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Naproxen Chest discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Naproxen Chest pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Naproxen Cholelithiasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naproxen Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen Confusional state 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen Constipation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen Coronary artery disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Crohn's disease 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Naproxen Cystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Naproxen Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Naproxen Depressed level of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Naproxen Depression 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Naproxen Dermatitis bullous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naproxen Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Naproxen Discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naproxen Disorientation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naproxen Disturbance in attention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naproxen Diverticulitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Naproxen Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Naproxen Drug reaction with eosinophilia and systemic symptoms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Duodenal ulcer 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Naproxen Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naproxen Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen Dysuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen Epistaxis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen Erythema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Naproxen Erythema multiforme 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Eye pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naproxen Faeces discoloured 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Naproxen Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naproxen Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Naproxen Gastric ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Gastrointestinal haemorrhage 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Naproxen Gastrointestinal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Naproxen Gastrooesophageal reflux disease 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen Haematemesis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Naproxen Haematochezia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen Haematuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen Haemoglobin decreased 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Naproxen Haemolytic anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Naproxen Hepatic failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Hyperkalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen Hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naproxen Hypoglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Naproxen Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Inflammation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Naproxen Influenza like illness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naproxen Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naproxen Intentional self-injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Joint swelling 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Naproxen Lip swelling 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Naproxen Liver function test abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen Loss of consciousness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Naproxen Malaise 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naproxen Melaena 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Naproxen Metabolic acidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Naproxen Migraine 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naproxen Mouth ulceration 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Naproxen Muscle spasms 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Naproxen Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Naproxen Musculoskeletal stiffness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naproxen Myocardial infarction 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Naproxen Nausea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Naproxen Neck pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naproxen Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Nervous system disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Nervousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naproxen Neuralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naproxen Oedema peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Naproxen Oesophageal ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Oesophagitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Naproxen Oropharyngeal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naproxen Osteoarthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naproxen Pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Naproxen Pain in extremity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Naproxen Palpitations 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen Pancreatic carcinoma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen Pancreatitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Naproxen Pharyngeal oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Proteinuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Pruritus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Naproxen Pulmonary embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Pyelonephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Naproxen Rash 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Naproxen Rectal haemorrhage 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Naproxen Renal failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen Renal impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Renal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naproxen Renal tubular necrosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Naproxen Respiratory distress 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen Sepsis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Shock 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen Stevens-Johnson syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen Stomatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Suicidal ideation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Suicide attempt 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Naproxen Swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Naproxen Swelling face 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Naproxen Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Naproxen Throat irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naproxen Thrombocytopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Naproxen Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Naproxen Toxic epidermal necrolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Ulcer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naproxen Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naproxen Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Naproxen Wheezing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naproxen sodium Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen sodium Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen sodium Angioedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naproxen sodium Cystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen sodium Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Naproxen sodium Diarrhoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen sodium Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen sodium Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naproxen sodium Duodenal ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen sodium Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen sodium Gastric ulcer 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Naproxen sodium Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen sodium Haematuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen sodium Headache 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen sodium Hepatic enzyme increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naproxen sodium Hyperhidrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naproxen sodium Hypertension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Naproxen sodium Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Naproxen sodium Insomnia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Naproxen sodium Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen sodium Melaena 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen sodium Nephrotic syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen sodium Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen sodium Peptic ulcer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naproxen sodium Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen sodium Pyrexia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen sodium Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen sodium Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen sodium Renal failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naproxen sodium Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naproxen sodium Stevens-Johnson syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen sodium Stomatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen sodium Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Naproxen sodium Tinnitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naproxen sodium Toxic epidermal necrolysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Naproxen sodium Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Naproxen sodium Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Naproxen sodium Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Naproxen sodium Visual impairment 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Naproxen sodium Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Nebivolol Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Nebivolol Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nebivolol Bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Nebivolol Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nebivolol Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nebivolol Dizziness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Nebivolol Drug abuse 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nebivolol Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nebivolol Hypertensive crisis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nebivolol Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Nebivolol Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nebivolol Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nebivolol Renal failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nebivolol Somnolence 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Nebivolol Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nebivolol Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nebivolol hydrochloride Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nebivolol hydrochloride Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nelarabine Aspartate aminotransferase increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nelarabine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nelarabine Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nelarabine Febrile neutropenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nelarabine Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nelarabine Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nelarabine Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nelarabine Neurotoxicity 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Nelarabine Neutropenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nelarabine Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nelarabine Polyneuropathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nelarabine Pyrexia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nelarabine Sensory disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nelarabine Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nepafenac Eye irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nepafenac Eye pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nepafenac Ocular hyperaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nepafenac Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nepafenac Visual acuity reduced 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nepafenac Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Neratinib Abdominal discomfort 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Neratinib Abdominal pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Neratinib Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Neratinib Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Neratinib Asthenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Neratinib Blood potassium decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Neratinib Blood pressure decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Neratinib Cough 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Neratinib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Neratinib Decreased appetite 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Neratinib Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Neratinib Diarrhoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Neratinib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Neratinib Dyspepsia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Neratinib Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Neratinib Fatigue 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Neratinib Feeling abnormal 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Neratinib Gastrooesophageal reflux disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Neratinib Headache 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Neratinib Hypoaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Neratinib Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Neratinib Malaise 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Neratinib Metastases to central nervous system 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Neratinib Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Neratinib Nausea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Neratinib Oropharyngeal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Neratinib Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Neratinib Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Neratinib Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Neratinib Renal failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Neratinib Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Neratinib Vomiting 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Neratinib Weight decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nevirapine Abdominal pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nevirapine Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nevirapine Anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nevirapine Asthenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nevirapine Blister 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nevirapine Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nevirapine Conjunctival hyperaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nevirapine Conjunctivitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nevirapine Death 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Nevirapine Dermatitis bullous 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nevirapine Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nevirapine Drug resistance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nevirapine Drug-induced liver injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nevirapine Embolism venous 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nevirapine Eosinophilia 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Nevirapine Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nevirapine Gastroenteritis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nevirapine Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nevirapine Hepatotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nevirapine Hypertension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nevirapine Medication residue present 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nevirapine Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nevirapine Nervous system disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nevirapine Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nevirapine Oral disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nevirapine Photophobia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nevirapine Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nevirapine Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Nevirapine Pruritus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nevirapine Pyrexia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nevirapine Rash 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nevirapine Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nevirapine Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nevirapine Respiratory distress 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nevirapine Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nevirapine Speech disorder 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Nevirapine Stevens-Johnson syndrome 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Nevirapine Toxic epidermal necrolysis 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Nevirapine Treatment failure 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Nevirapine Ulcer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nevirapine Vomiting 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Niacin Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nicotine Abdominal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nicotine Abnormal dreams 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Anaphylactic reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Anger 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Angina pectoris 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Arrhythmia 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Nicotine Arthralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Blood glucose increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nicotine Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nicotine Choking 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nicotine Confusional state 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Coronary artery disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nicotine Death 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Nicotine Dehydration 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nicotine Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Disturbance in attention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nicotine Drug dependence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Dysphagia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Dyspnoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Feeling abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Flatulence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Foetal growth restriction 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Nicotine Hallucination 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Hiccups 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Hyperhidrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nicotine Hypothermia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nicotine Ill-defined disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Loss of consciousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Lung neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Malaise 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Maternal drugs affecting foetus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nicotine Mental disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nicotine Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Nervousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Nightmare 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Oral discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Pharyngeal oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Nicotine Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Pyrexia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nicotine Respiratory disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nicotine Restlessness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nicotine Sleep disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Stress 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Nicotine Swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Throat irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Tooth disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Unresponsive to stimuli 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nicotine Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nicotine Withdrawal syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nifedipine Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nifedipine Atrial septal defect 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Nifedipine Atrioventricular block 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nifedipine Blood pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nifedipine Bradycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nifedipine Burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nifedipine Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nifedipine Cardiac disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nifedipine Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nifedipine Cardiogenic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nifedipine Chest discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nifedipine Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nifedipine Coma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nifedipine Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nifedipine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nifedipine Depressed level of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nifedipine Drug hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nifedipine Drug-induced liver injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nifedipine Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nifedipine Foetal death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nifedipine Foetal growth restriction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nifedipine Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nifedipine Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nifedipine Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nifedipine Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nifedipine Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nifedipine Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nifedipine Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nifedipine Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nifedipine Pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nifedipine Pallor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nifedipine Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nifedipine Peripheral swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nifedipine Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 1.0 Nifedipine Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nifedipine Seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nifedipine Shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nifedipine Somnolence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nifedipine Suicide attempt 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nifedipine Swelling face 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nifedipine Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nifedipine Visual impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Abasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Abdominal discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Abdominal pain upper 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Acute coronary syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Acute kidney injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Acute myeloid leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Acute myocardial infarction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Acute respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Alanine aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Altered state of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Anaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Anaphylactic reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Angina pectoris 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Anorectal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Apathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Aphasia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Arrhythmia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Arthralgia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Arthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Ascites 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Asthenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Atelectasis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Atrial fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Bacterial infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Balance disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Blindness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Blister 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Blood cholesterol increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Blood count abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Blood creatinine increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Blood disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Blood lactate dehydrogenase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Blood potassium decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Blood potassium increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Blood pressure decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Blood pressure increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Blood triglycerides increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Blood urea increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Bone marrow failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Bone pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Bradycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Brain oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Bronchospasm 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Bursitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib C-reactive protein increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Cardiac disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Cardiac failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Cardiac failure congestive 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Cardiac tamponade 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Cardiomegaly 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Cardiotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Cardiovascular disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Cerebral haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Cerebral infarction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Cerebral ischaemia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Chest discomfort 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Cholecystitis acute 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Cholelithiasis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Chronic kidney disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Circulatory collapse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Cold sweat 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Colon cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Conjunctivitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Decreased appetite 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Deep vein thrombosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Dehydration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Dementia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Dental caries 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Depressed level of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Depressed mood 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Depression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Dermatitis allergic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Diarrhoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Diplopia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Disorientation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Disseminated intravascular coagulation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Disturbance in attention 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Drug eruption 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Drug intolerance 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Drug resistance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Dry eye 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Dry skin 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Dysarthria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Dysgeusia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Dysmenorrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Dysphagia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Dysphonia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Dyspnoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Dyspnoea exertional 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Dysstasia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Ear pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Eating disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Eczema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Electrocardiogram QT prolonged 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Emotional distress 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Encephalopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Epistaxis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Eructation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Erythema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Eye disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Eye haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Eye pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Eye pruritus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Face oedema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Facial paralysis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Fear 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Febrile neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Feeding disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Feeling abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Femur fracture 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Flushing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Gait disturbance 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Gamma-glutamyltransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Gastric cancer 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Gastric disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Gastric haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Gastrooesophageal reflux disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Generalised oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Gingival bleeding 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Glaucoma 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Haematemesis 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Haematochezia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Haematuria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Haemoglobin decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Haemorrhage intracranial 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Headache 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Hemiparesis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Hemiplegia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Hepatic cirrhosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Hepatic steatosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Hepatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Hepatomegaly 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Hepatotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Hiccups 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Hyperglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Hyperkalaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Hyperlipidaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Hypertensive crisis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Hypertriglyceridaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Hyperuricaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Hypoacusis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Hypoaesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Hypokalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Hypokinesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Hypophagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Hypophosphataemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Hypotension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Hypothyroidism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Hypoxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Ileus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Increased appetite 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Infection 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Inflammation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Insomnia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Interstitial lung disease 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Intervertebral disc protrusion 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Intestinal obstruction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Iron deficiency anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Ischaemic stroke 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Jaundice 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Joint swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Lethargy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Leukocytosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Limb discomfort 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Lip swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Localised infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Loss of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Lower respiratory tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Lung disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Lung infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Lung infiltration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Lymphocyte count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Lymphoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Malaise 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Malignant neoplasm progression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Malnutrition 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Menstruation irregular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Metabolic acidosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Metastases to lung 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Micturition urgency 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Migraine 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Mitral valve incompetence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Mobility decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Mood altered 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Motor dysfunction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Movement disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Muscular weakness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Musculoskeletal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Myocardial ischaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Myopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Nasal congestion 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Nausea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Neck pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Necrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Neutrophil count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Night sweats 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Obesity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Ocular hyperaemia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Oedema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Oedema peripheral 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Oral candidiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Osteomyelitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Osteonecrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Oxygen saturation decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Pain in extremity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Pallor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Palpitations 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Pancreatic carcinoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Pancreatitis acute 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Paraesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Paralysis 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Paresis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Parkinson's disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Pericardial effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Pericarditis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Peripheral coldness 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Nilotinib Peripheral ischaemia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Peripheral swelling 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Peripheral vascular disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Petechiae 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Photophobia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Photosensitivity reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Pigmentation disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Platelet count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Pleural effusion 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Pleurisy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Pneumonia aspiration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Pneumonitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Pollakiuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Polyneuropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Poor quality sleep 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Prostate cancer 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Proteinuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Pruritus generalised 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Pulmonary congestion 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Pulmonary embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Pulmonary fibrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Pulmonary haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Pulmonary oedema 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Pyrexia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Rectal haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Red blood cell sedimentation rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Renal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Renal impairment 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Respiratory disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Respiratory distress 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Respiratory tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Rhinorrhoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Sensory loss 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Skin cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Skin disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Skin ulcer 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Sleep apnoea syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Sleep disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Sneezing 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Speech disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Spinal fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Splenomegaly 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Squamous cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Stomatitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Stress 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Subarachnoid haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Subdural haematoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Swollen tongue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Syncope 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Throat irritation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Thrombosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Toothache 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Transaminases increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Troponin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Tumour lysis syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Ulcer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Urine output decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Vaginal haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Varicose vein 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Vertigo 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Viral infection 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Nilotinib Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nilotinib Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Nilotinib Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Nilotinib Weight decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Wheezing 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib White blood cell count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nilotinib White blood cell count increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nilotinib Withdrawal syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nintedanib Abdominal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Acute coronary syndrome 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Acute myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Acute respiratory distress syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Acute respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Ageusia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Alanine aminotransferase increased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Alopecia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Anal incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Angina pectoris 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Aphasia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Appendicitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Arthritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Ascites 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Aspartate aminotransferase increased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Atrial fibrillation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Blindness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nintedanib Blood alkaline phosphatase increased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Blood bilirubin increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Blood creatinine increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Blood glucose decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Blood magnesium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Blood urine present 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Cachexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Cardiac disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Cardiac failure 1.0 0.0 1.0 1.0 0.0 0.0 0.0 Nintedanib Cardiac failure congestive 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Cardiogenic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Cardiomyopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Cardiovascular disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Cerebral haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Cerebral infarction 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Nintedanib Cerebrovascular accident 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Chest discomfort 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Nintedanib Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Cholangitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Cholecystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Chronic obstructive pulmonary disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Circulatory collapse 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Clostridium difficile infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Cognitive disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Colitis ischaemic 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Colitis ulcerative 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Colon cancer 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Contusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Coronary artery disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Cystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Decreased appetite 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Deep vein thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nintedanib Diabetes mellitus 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Nintedanib Diarrhoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Diarrhoea haemorrhagic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Discomfort 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Diverticulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Drug-induced liver injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Dry mouth 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Dysgeusia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Dyspepsia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Dysphagia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Dysphonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Dyspnoea exertional 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Eating disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Ejection fraction decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Embolism venous 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Epistaxis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Facial paralysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Faeces discoloured 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Nintedanib Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Feeding disorder 1.0 0.0 1.0 1.0 0.0 0.0 0.0 Nintedanib Feeling abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Flatulence 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Nintedanib Fluid retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Frequent bowel movements 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nintedanib Full blood count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Gallbladder disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Gamma-glutamyltransferase increased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Gastric cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nintedanib Gastric disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Gastroenteritis viral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Gastrointestinal haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Gastrooesophageal reflux disease 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Nintedanib Generalised oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Gout 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Haematemesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Haematochezia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Haematoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Haemoptysis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Haemorrhagic stroke 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Haemorrhoids 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Hallucination 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Heart rate decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Heart rate increased 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Nintedanib Hepatic enzyme increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Hepatic function abnormal 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Hepatitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Herpes zoster 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Nintedanib Hip fracture 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Hypoaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Hypokalaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Hypomagnesaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Hyponatraemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Hypoxia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Ill-defined disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Interstitial lung disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Intestinal perforation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Ischaemic stroke 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Large intestine perforation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Lethargy 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Nintedanib Leukopenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Liver disorder 1.0 0.0 1.0 1.0 0.0 0.0 0.0 Nintedanib Liver function test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Liver function test increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Loss of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Lower respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Lung disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Lung infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Lung infiltration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Melaena 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Memory impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Muscle spasms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Myocardial ischaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Myositis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Nasal congestion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Nephrolithiasis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Nintedanib Nephrotic syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Neutropenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Oesophagitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Oropharyngeal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Oxygen saturation decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Pancytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Paraesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Pericardial effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Platelet count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Pleural effusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Pneumonia aspiration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Pneumonia bacterial 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Pneumothorax 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Pollakiuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Productive cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Pulmonary alveolar haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Pulmonary congestion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Pulmonary embolism 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Pulmonary fibrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Pulmonary haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Pulmonary hypertension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Pulmonary mass 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Pyrexia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Rales 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Rash generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Renal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Renal failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Renal impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Respiratory disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Respiratory distress 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Respiratory tract congestion 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nintedanib Respiratory tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Rhinorrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Sepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Sinus disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nintedanib Sinusitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Skin discolouration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Skin lesion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Speech disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Stomatitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Subdural haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Supraventricular tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Tachycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nintedanib Thrombocytopenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Tinnitus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Transient ischaemic attack 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Unevaluable event 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Upper respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Vaginal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Vasculitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nintedanib Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Weight increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nintedanib Wheezing 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nintedanib White blood cell count decreased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Nintedanib White blood cell count increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Niraparib Abdominal discomfort 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Abdominal distension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Abdominal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Abdominal pain lower 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Abdominal pain upper 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Acute kidney injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Alanine aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Amnesia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Anxiety 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Arthralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Arthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Aspartate aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Asthenia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Back pain 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Balance disorder 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Blister 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Blood alkaline phosphatase increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Niraparib Blood cholesterol increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Blood count abnormal 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Blood creatinine increased 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Blood glucose increased 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Blood magnesium decreased 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Blood potassium decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Blood pressure fluctuation 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Blood pressure increased 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Blood urea increased 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Bone marrow failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Bone pain 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Breast pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Bronchitis 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Cardiac disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Niraparib Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Niraparib Cognitive disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Niraparib Constipation 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Contusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Cough 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Crying 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Niraparib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Niraparib Decreased appetite 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Niraparib Depressed mood 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Depression 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Diarrhoea 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Dizziness postural 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Drug intolerance 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Dry mouth 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Dysgeusia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Dyspnoea exertional 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Ear pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Emotional distress 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Epistaxis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Erythema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Fear 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Niraparib Febrile neutropenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Niraparib Feeding disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Feeling abnormal 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Feeling jittery 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Flatulence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Fluid retention 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Full blood count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Gait disturbance 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Gastroenteritis viral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Gastrooesophageal reflux disease 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Gingival bleeding 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Niraparib Haematemesis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Haematochezia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Haematocrit decreased 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Haematoma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Haematuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Haemoglobin decreased 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Headache 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Heart rate increased 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Heart rate irregular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Hepatic enzyme increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Herpes zoster 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Hot flush 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Hyperhidrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Hypertensive crisis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Hypoaesthesia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Niraparib Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Hypothyroidism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Ileus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Niraparib Inflammation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Influenza like illness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Insomnia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Niraparib Laboratory test abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Limb discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Liver function test abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Niraparib Lymphadenopathy 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Lymphoedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Malaise 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Malignant neoplasm progression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Mania 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Niraparib Memory impairment 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Mental disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Metastases to central nervous system 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Metastases to liver 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Middle insomnia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Migraine 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Mood altered 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Mucosal inflammation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Niraparib Muscle spasms 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Muscular weakness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Musculoskeletal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Myalgia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Myelodysplastic syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Nasal congestion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Nasopharyngitis 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Nausea 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Neoplasm progression 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Nervousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Neuralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Neutrophil count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Night sweats 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Nodule 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Oedema peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Oral pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Oropharyngeal pain 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Pain in extremity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Palpitations 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Pancytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Paraesthesia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Peripheral swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Petechiae 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Photosensitivity reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Platelet count decreased 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Pleural effusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Niraparib Pollakiuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Psychomotor hyperactivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Pulmonary embolism 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Niraparib Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Niraparib Rash 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Rash pruritic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Rectal haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Red blood cell count decreased 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Renal failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Retching 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Rhinorrhoea 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Niraparib Sepsis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Niraparib Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Niraparib Sinus congestion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Sinus disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Sinusitis 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Skin discolouration 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Sleep disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Sluggishness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Stomatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Stress 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Throat irritation 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Thrombosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib Tremor 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Unevaluable event 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Urinary tract infection 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Vaginal haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Visual impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Niraparib Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Weight decreased 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Niraparib Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Niraparib White blood cell count decreased 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Nitisinone Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitisinone Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitisinone Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nitisinone Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nitisinone Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitisinone Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitisinone Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nitisinone Hepatic cirrhosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nitisinone Hepatic encephalopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nitisinone Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nitisinone Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitisinone Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitisinone Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitisinone Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitisinone Seizure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nitisinone Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitisinone Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitric oxide Acute kidney injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nitric oxide Blood pressure decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nitric oxide Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nitric oxide Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nitric oxide Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nitric oxide Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nitric oxide Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nitric oxide Hypoxia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nitric oxide Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nitric oxide Oxygen saturation decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nitric oxide Pneumothorax 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nitric oxide Premature baby 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nitric oxide Pulmonary haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nitric oxide Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nitric oxide Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nitric oxide Shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nitrofurantoin Abdominal pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Nitrofurantoin Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nitrofurantoin Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nitrofurantoin Arthralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nitrofurantoin Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nitrofurantoin Chest pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Nitrofurantoin Chills 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Nitrofurantoin Confusional state 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nitrofurantoin Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitrofurantoin Cough 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Nitrofurantoin Decreased appetite 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Nitrofurantoin Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nitrofurantoin Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nitrofurantoin Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Nitrofurantoin Drug-induced liver injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Nitrofurantoin Dyspnoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Nitrofurantoin Dyspnoea exertional 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitrofurantoin Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitrofurantoin Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nitrofurantoin Haemolytic anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitrofurantoin Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Nitrofurantoin Hepatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitrofurantoin Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nitrofurantoin Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitrofurantoin Hypoaesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Nitrofurantoin Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitrofurantoin Interstitial lung disease 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Nitrofurantoin Lung disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nitrofurantoin Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nitrofurantoin Nausea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Nitrofurantoin Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nitrofurantoin Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nitrofurantoin Pleural effusion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Nitrofurantoin Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nitrofurantoin Pulmonary fibrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Nitrofurantoin Pyrexia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Nitrofurantoin Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nitrofurantoin Rash erythematous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nitrofurantoin Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitrofurantoin Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Nitrofurantoin Somnolence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Nitrofurantoin Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nitrofurantoin Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitrofurantoin Vomiting 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Nitroglycerin Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitroglycerin Angina pectoris 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nitroglycerin Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nitroglycerin Cardiac arrest 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nitroglycerin Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitroglycerin Cerebrovascular accident 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nitroglycerin Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitroglycerin Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nitroglycerin Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitroglycerin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nitroglycerin Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitroglycerin Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitroglycerin Drug hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nitroglycerin Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitroglycerin Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nitroglycerin Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nitroglycerin Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Nitroglycerin Myocardial ischaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nitroglycerin Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitroglycerin Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nitroglycerin Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitroglycerin Respiratory failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitroglycerin Seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Nitroglycerin Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitroglycerin Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitrous oxide Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitrous oxide Asphyxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nitrous oxide Ataxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitrous oxide Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitrous oxide Drug abuse 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Nitrous oxide Drug dependence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitrous oxide Euphoric mood 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nitrous oxide Hypoaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitrous oxide Paraesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitrous oxide Polyneuropathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nitrous oxide Pulmonary embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Norepinephrine Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Norepinephrine Bradycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Norepinephrine Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Norepinephrine Cardiogenic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Norepinephrine Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Norepinephrine Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Norepinephrine Pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Norepinephrine Tachycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Norepinephrine bitartrate Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Norethindrone Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Norethindrone Haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Norethindrone Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Norethindrone Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Norethindrone Pulmonary embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nortriptyline Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nortriptyline Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nortriptyline Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Nortriptyline Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Nortriptyline Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nortriptyline Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nortriptyline Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Nortriptyline hydrochloride Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Obeticholic acid Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Obeticholic acid Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Obeticholic acid Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Obeticholic acid Cerebrovascular accident 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Obeticholic acid Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Obeticholic acid Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Obeticholic acid Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Obeticholic acid Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Obeticholic acid Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Obeticholic acid Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Obeticholic acid Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Obeticholic acid Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Obeticholic acid Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Obeticholic acid Erythema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Obeticholic acid Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Obeticholic acid Femur fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Obeticholic acid Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Obeticholic acid Gastrooesophageal reflux disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Obeticholic acid Haematemesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Obeticholic acid Haematochezia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Obeticholic acid Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Obeticholic acid Hepatic cirrhosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Obeticholic acid Hepatic encephalopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Obeticholic acid Hepatic enzyme abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Obeticholic acid Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Obeticholic acid Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Obeticholic acid Hip fracture 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Obeticholic acid Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Obeticholic acid Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Obeticholic acid Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Obeticholic acid Liver disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Obeticholic acid Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Obeticholic acid Myocardial infarction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Obeticholic acid Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Obeticholic acid Neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Obeticholic acid Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Obeticholic acid Platelet count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Obeticholic acid Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Obeticholic acid Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Obeticholic acid Pruritus generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Obeticholic acid Pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Obeticholic acid Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Obeticholic acid Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Obeticholic acid Sepsis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Obeticholic acid Swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Obeticholic acid Throat irritation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Obeticholic acid Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Obeticholic acid Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Octreotide Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide Cardiac failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Octreotide Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Octreotide Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide Eating disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide Erythema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Octreotide Flatulence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide Fluid retention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Octreotide Haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Octreotide Heart rate decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Octreotide Hyperglycaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Octreotide Hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Octreotide Hypotension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Octreotide Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide Productive cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Octreotide Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Octreotide Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Octreotide acetate Abdominal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Acne 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Octreotide acetate Agitation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Octreotide acetate Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Octreotide acetate Amenorrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Octreotide acetate Amnesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Octreotide acetate Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Octreotide acetate Anxiety 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Octreotide acetate Appendicitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Arrhythmia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Octreotide acetate Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 1.0 Octreotide acetate Arthritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Arthropathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Octreotide acetate Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Asthma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Octreotide acetate Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Breast pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Bronchospasm 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Candida infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Cardiac disorder 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Cholecystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Contusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Cystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Deafness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Octreotide acetate Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Depression 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Diabetes mellitus 0.0 0.0 1.0 0.0 0.0 0.0 1.0 Octreotide acetate Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Discomfort 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Dyspepsia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Dyspnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Ear disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Octreotide acetate Ear infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Octreotide acetate Endocrine disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Octreotide acetate Epistaxis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Octreotide acetate Erythema 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Facial paralysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Faeces discoloured 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 1.0 Octreotide acetate Feeling abnormal 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Flatulence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Flushing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Galactorrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Octreotide acetate Gallbladder disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Gastrointestinal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Octreotide acetate Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Haemorrhoids 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Octreotide acetate Headache 0.0 0.0 1.0 0.0 0.0 0.0 1.0 Octreotide acetate Hepatic steatosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Octreotide acetate Hernia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Hot flush 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Hypoacusis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Octreotide acetate Hypoaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Hypoglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Hypothyroidism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Octreotide acetate Ill-defined disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Octreotide acetate Immune system disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Octreotide acetate Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Injection site pain 0.0 0.0 1.0 0.0 0.0 0.0 1.0 Octreotide acetate Injection site reaction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Insomnia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Octreotide acetate Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Irritability 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Octreotide acetate Ischaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Jaundice 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Jaundice cholestatic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Loss of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Malaise 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Malnutrition 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Octreotide acetate Menstrual disorder 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Mental disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Octreotide acetate Metrorrhagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Mouth ulceration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Multiple fractures 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Muscle spasms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Muscular weakness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Octreotide acetate Myalgia 0.0 0.0 1.0 0.0 0.0 0.0 1.0 Octreotide acetate Nasal congestion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Octreotide acetate Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 1.0 Octreotide acetate Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Neoplasm malignant 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Octreotide acetate Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Nervous system disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Octreotide acetate Nervousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Octreotide acetate Neuralgia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Octreotide acetate Oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Octreotide acetate Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Oropharyngeal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Octreotide acetate Oropharyngeal pain 0.0 0.0 1.0 0.0 0.0 0.0 1.0 Octreotide acetate Osteoarthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Octreotide acetate Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Pain in extremity 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Paraesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Pharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Phlebitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Pollakiuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Polyuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Psychomotor hyperactivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Psychotic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Pulmonary mass 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Octreotide acetate Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Renal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Seizure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Sensory loss 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Octreotide acetate Sleep disorder 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Octreotide acetate Syncope 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Tenderness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Octreotide acetate Tension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Octreotide acetate Thrombocytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Octreotide acetate Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Octreotide acetate Varicose vein 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Octreotide acetate Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Vision blurred 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Octreotide acetate Visual impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Octreotide acetate Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Weight decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Octreotide acetate Weight increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Octreotide acetate Wheezing 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ofatumumab Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ofatumumab Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ofatumumab Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ofatumumab Back pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Ofatumumab Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ofatumumab Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ofatumumab Chills 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ofatumumab Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ofatumumab Dyspnoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ofatumumab Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ofatumumab Febrile neutropenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ofatumumab Flushing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ofatumumab Fungal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ofatumumab Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ofatumumab Herpes zoster 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ofatumumab Hyperhidrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ofatumumab Hypotension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ofatumumab Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ofatumumab Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ofatumumab Leukopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ofatumumab Lower respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ofatumumab Lung infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ofatumumab Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ofatumumab Nasal congestion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ofatumumab Nasopharyngitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ofatumumab Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ofatumumab Neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ofatumumab Pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ofatumumab Pancytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ofatumumab Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ofatumumab Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ofatumumab Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ofatumumab Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ofatumumab Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ofatumumab Sinusitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ofatumumab Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ofatumumab Tumour lysis syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ofatumumab Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ofatumumab Urticaria 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ofloxacin Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ofloxacin Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ofloxacin Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ofloxacin Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ofloxacin Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ofloxacin Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ofloxacin Confusional state 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ofloxacin Drug interaction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ofloxacin Drug reaction with eosinophilia and systemic symptoms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ofloxacin Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ofloxacin Erythema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ofloxacin Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ofloxacin Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ofloxacin Haematoma 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ofloxacin Haematuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ofloxacin Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ofloxacin Hepatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ofloxacin Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ofloxacin Hypertension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ofloxacin Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ofloxacin Leukopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ofloxacin Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ofloxacin Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ofloxacin Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ofloxacin Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ofloxacin Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ofloxacin Palpitations 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ofloxacin Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ofloxacin Photosensitivity reaction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ofloxacin Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ofloxacin Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ofloxacin Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ofloxacin Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ofloxacin Renal failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ofloxacin Stevens-Johnson syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ofloxacin Tendon rupture 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ofloxacin Tendonitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ofloxacin Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ofloxacin Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ofloxacin Toxic epidermal necrolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ofloxacin Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ofloxacin Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ofloxacin Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Abdominal distension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Abdominal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Abdominal pain upper 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Olanzapine Abdominal tenderness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olanzapine Acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Acute hepatic failure 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Acute myocardial infarction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Acute respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Aggression 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Agitation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Agranulocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Akathisia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Altered state of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Amenorrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Amnesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Anger 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Angiopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Apathy 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Aphasia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Olanzapine Arrhythmia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Ascites 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Aspartate aminotransferase increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Asphyxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Aspiration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Asthma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olanzapine Ataxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Atelectasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Atrial fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Atrial septal defect 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Olanzapine Atrioventricular block 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Atrioventricular block second degree 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Balance disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Blood albumin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Blood cholesterol increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Blood creatine phosphokinase increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Blood creatinine increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Blood glucose increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Blood lactate dehydrogenase increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Blood potassium decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Blood pressure decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Blood pressure fluctuation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Blood pressure increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Blood triglycerides increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Blood urea increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Body temperature decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olanzapine Body temperature increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Bradycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Bradyphrenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Brain injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Brain oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Breast enlargement 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Breast pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olanzapine Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine C-reactive protein increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Candida infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Cardiac disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Cardiac failure 1.0 1.0 0.0 1.0 1.0 0.0 0.0 Olanzapine Cardiac failure congestive 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Cardiomyopathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Cardiotoxicity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Cardiovascular disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olanzapine Catatonia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Cerebral haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Cerebral infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Cerebrovascular accident 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Chest pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Chills 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Choking 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Chronic kidney disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olanzapine Clostridium difficile infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Cognitive disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Colitis ischaemic 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Colitis ulcerative 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Coma 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Confusional state 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Olanzapine Congestive cardiomyopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Coordination abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Cough 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Crying 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Cyanosis 1.0 1.0 0.0 1.0 1.0 0.0 0.0 Olanzapine Deafness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Decreased appetite 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Decubitus ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Deep vein thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Delusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Depersonalisation/derealisation disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olanzapine Depressed level of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Depressed mood 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Dermatitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Diabetes mellitus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Diabetic ketoacidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Diplopia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Disease progression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Disorientation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Disturbance in attention 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Drug abuse 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Drug dependence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Drug eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Drug hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Drug intolerance 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Drug withdrawal syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Drug-induced liver injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Dry eye 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Dry mouth 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Dry skin 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Dysarthria 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Dyskinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Dysphagia 1.0 1.0 0.0 0.0 1.0 0.0 0.0 Olanzapine Dysphoria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Dyspnoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Dysstasia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Dystonia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Ear pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Eating disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Electrocardiogram abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Electrolyte imbalance 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Embolism venous 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Emotional disorder 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Emotional distress 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Encephalitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Encephalopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Epilepsy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Epistaxis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Erectile dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Olanzapine Erythema 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Euphoric mood 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Extrapyramidal disorder 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Eye pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Eye swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olanzapine Facial paralysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Faecaloma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Fatigue 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Olanzapine Febrile neutropenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Feeling abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Flat affect 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Fluid retention 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Flushing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Fracture 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Gait disturbance 1.0 1.0 1.0 1.0 0.0 0.0 0.0 Olanzapine Galactorrhoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Gamma-glutamyltransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Gastrointestinal disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Gastrooesophageal reflux disease 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Generalised tonic-clonic seizure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Granulocytopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olanzapine Haematocrit decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Haematuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Haemoglobin decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Haemoptysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Hallucination, auditory 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Hallucination, visual 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Heart rate decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olanzapine Heart rate increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Heart rate irregular 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Hepatic function abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Hepatic steatosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Hiccups 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olanzapine Hot flush 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olanzapine Hypercholesterolaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Hyperglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Hyperkalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Hyperlipidaemia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Hypernatraemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Hyperreflexia 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Olanzapine Hypersensitivity 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Hypersomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Hypertension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Hyperthermia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Hypertonia 0.0 1.0 1.0 0.0 1.0 0.0 0.0 Olanzapine Hypertriglyceridaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Hyperventilation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Hypoaesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Hypocalcaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Hypoglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Hypokinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Hypomagnesaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Hypophagia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Hypophosphataemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Hypothermia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Hypothyroidism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Hypotonia 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Olanzapine Hypoxia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Ileus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Ileus paralytic 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Inappropriate antidiuretic hormone secretion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Incontinence 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Increased appetite 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Induration 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Influenza like illness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Injury 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Insomnia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Intentional self-injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Intestinal obstruction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Irritability 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Ischaemic stroke 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Jaundice 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Joint swelling 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Keratitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Lactic acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Left ventricular dysfunction 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Lethargy 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Olanzapine Leukocytosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Libido decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Liver injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Loss of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Loss of libido 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Lower respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Lung neoplasm malignant 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Malaise 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Mania 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Memory impairment 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Menstruation irregular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olanzapine Mental disability 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Mental disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Mental impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Mental status changes 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Metabolic acidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Metabolic disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Miosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Mobility decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Motor dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Mouth ulceration 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olanzapine Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Muscle contractions involuntary 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Muscle rigidity 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Muscle spasms 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Olanzapine Muscle twitching 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Musculoskeletal pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Musculoskeletal stiffness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Myalgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Mydriasis 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Olanzapine Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Myocardial ischaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Myopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Nasal congestion 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Nausea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Nervous system disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Nervousness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Neuralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Neuroleptic malignant syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Neurological symptom 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Neutrophil count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Nightmare 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Obesity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Ocular hyperaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olanzapine Oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Oedema peripheral 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Oesophagitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Oropharyngeal pain 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Olanzapine Orthostatic hypotension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Osteoporosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Oxygen saturation decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Pallor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Palpitations 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Pancreatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olanzapine Pancreatitis acute 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Pancytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Panic attack 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Paraesthesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Paralysis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olanzapine Paranoia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Parkinson's disease 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Parkinsonism 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Personality disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Petechiae 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Pharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Phlebitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Photosensitivity reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Pleural effusion 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Pneumonia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Pneumonia aspiration 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Pollakiuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Polyuria 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Olanzapine Priapism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Psychomotor hyperactivity 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Psychotic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Pulmonary congestion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Pulmonary embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Pulmonary haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Rash maculo-papular 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Rectal haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olanzapine Red blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Renal failure 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Renal impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Respiratory depression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Respiratory disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Respiratory distress 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Olanzapine Respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Restlessness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Salivary hypersecretion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Sedation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Sepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Septic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Serotonin syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Sexual dysfunction 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Olanzapine Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Sinus bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Sinus disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olanzapine Sinus tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Skin discolouration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Skin disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olanzapine Skin lesion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Sleep apnoea syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Sleep disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Somnolence 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Olanzapine Sopor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Speech disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Status epilepticus 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Stress 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Stupor 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Subarachnoid haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Sudden death 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Suicidal ideation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Suicide attempt 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Supraventricular extrasystoles 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Swelling face 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Swollen tongue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Syncope 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Tachypnoea 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Olanzapine Tardive dyskinesia 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Olanzapine Tension 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Olanzapine Thinking abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Thirst 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Thrombocytopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Thrombosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Tinnitus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Torsade de pointes 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Transaminases increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Tremor 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Olanzapine Unresponsive to stimuli 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Urinary incontinence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Urinary tract infection 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Vaginal haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Ventricular arrhythmia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Ventricular extrasystoles 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Ventricular fibrillation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine Ventricular tachycardia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Vertigo 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Vision blurred 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Visual acuity reduced 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Visual impairment 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Olanzapine Vomiting 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Olanzapine Weight decreased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine Weight increased 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Olanzapine White blood cell count increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine Withdrawal syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Aggression 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Agitation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Akathisia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Amnesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Anxiety 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Asthenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Ataxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Blood creatine phosphokinase increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Cerebrovascular accident 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Cognitive disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Coma 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Confusional state 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Deep vein thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Delirium 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Dizziness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Dry mouth 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Dysarthria 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Dyskinesia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Electrocardiogram QT prolonged 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Extrapyramidal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Hallucination 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Headache 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Heart rate increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Hyperhidrosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Hypertension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Loss of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Neuroleptic malignant syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Parkinsonism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Pneumonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Pulmonary embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Restlessness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Sedation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Seizure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Somnolence 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Speech disorder 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Stupor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Suicide attempt 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Syncope 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Tremor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Olanzapine pamoate Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olanzapine pamoate White blood cell count increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olaparib Abdominal distension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Abdominal pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Abdominal pain upper 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olaparib Acute myeloid leukaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olaparib Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olaparib Anaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olaparib Angioedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olaparib Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olaparib Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Asthenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olaparib Blood bilirubin increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olaparib Blood creatinine increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olaparib Blood pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olaparib Bone marrow failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olaparib C-reactive protein increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olaparib Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olaparib Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olaparib Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olaparib Confusional state 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olaparib Constipation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Dehydration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Olaparib Depression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olaparib Diarrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Olaparib Disease recurrence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olaparib Drug intolerance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Drug resistance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Dyspepsia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Dysphagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Dyspnoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olaparib Enteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olaparib Fatigue 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Olaparib Febrile neutropenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olaparib Feeding disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Flank pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olaparib Gastric ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olaparib Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olaparib Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Haematocrit decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olaparib Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olaparib Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Hepatic function abnormal 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olaparib Hepatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olaparib Hot flush 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olaparib Hyperhidrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olaparib Hyperkalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olaparib Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olaparib Hyponatraemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Hypotension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Olaparib Ileus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Olaparib Intestinal obstruction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Olaparib Laboratory test abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Liver disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Lower respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olaparib Lung disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olaparib Lung infection 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Olaparib Lymphocyte count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olaparib Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Olaparib Memory impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olaparib Metastases to central nervous system 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olaparib Metastases to liver 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Metastases to lung 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Muscle spasms 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olaparib Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olaparib Myelodysplastic syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olaparib Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Nasopharyngitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Nausea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olaparib Neutrophil count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olaparib Pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Olaparib Pancreatic carcinoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olaparib Pancytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olaparib Pericardial effusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Olaparib Platelet count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olaparib Pleural effusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Pneumocystis jirovecii pneumonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olaparib Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Olaparib Pneumonitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olaparib Pulmonary embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olaparib Pulmonary mass 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olaparib Pyrexia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Olaparib Red blood cell count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olaparib Renal disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olaparib Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olaparib Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olaparib Small intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olaparib Stomatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olaparib Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Olaparib Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olaparib Vomiting 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Olaparib Weight decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olaparib Weight increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Olmesartan Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan Anaemia 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Olmesartan Anuria 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Olmesartan Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan Blood pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olmesartan Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan Decreased appetite 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Olmesartan Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan Drug-induced liver injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olmesartan Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan Enteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olmesartan Hypertension 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Olmesartan Hypertensive crisis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olmesartan Hypocalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan Hypomagnesaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan Hypotension 0.0 1.0 1.0 0.0 1.0 0.0 0.0 Olmesartan Malaise 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olmesartan Malnutrition 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan Metabolic acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan Pallor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan Premature baby 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Olmesartan Pyrexia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Olmesartan Renal failure 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Olmesartan Shock 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan medoxomil Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan medoxomil Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan medoxomil Alopecia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan medoxomil Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan medoxomil Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan medoxomil Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan medoxomil Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan medoxomil Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan medoxomil Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan medoxomil Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan medoxomil Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan medoxomil Dyspepsia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan medoxomil Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan medoxomil Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan medoxomil Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan medoxomil Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan medoxomil Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan medoxomil Hyperglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olmesartan medoxomil Hyperkalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Olmesartan medoxomil Hyperuricaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan medoxomil Insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan medoxomil Laboratory test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan medoxomil Liver function test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan medoxomil Malnutrition 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan medoxomil Musculoskeletal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan medoxomil Myalgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan medoxomil Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan medoxomil Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan medoxomil Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan medoxomil Pruritus 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Olmesartan medoxomil Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan medoxomil Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan medoxomil Transaminases increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan medoxomil Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olmesartan medoxomil Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Olopatadine hydrochloride Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Omacetaxine mepesuccinate Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Omacetaxine mepesuccinate Asthenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Omacetaxine mepesuccinate Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Omacetaxine mepesuccinate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Omacetaxine mepesuccinate Diarrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Omacetaxine mepesuccinate Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Omacetaxine mepesuccinate Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Omacetaxine mepesuccinate Full blood count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Omacetaxine mepesuccinate Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Omacetaxine mepesuccinate Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Omacetaxine mepesuccinate Pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Omacetaxine mepesuccinate Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Omacetaxine mepesuccinate Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Omacetaxine mepesuccinate Renal failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Omacetaxine mepesuccinate Sepsis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Omacetaxine mepesuccinate Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Omacetaxine mepesuccinate White blood cell count increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Omega-3-acid ethyl esters Angina pectoris 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Omega-3-acid ethyl esters Cardiac disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Omega-3-acid ethyl esters Cataract 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Omega-3-acid ethyl esters Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Omega-3-acid ethyl esters Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Omega-3-acid ethyl esters Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Omega-3-acid ethyl esters Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Omega-3-acid ethyl esters Epistaxis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Omega-3-acid ethyl esters Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Omega-3-acid ethyl esters Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Omega-3-acid ethyl esters Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Omega-3-acid ethyl esters Malaise 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Omega-3-acid ethyl esters Neoplasm 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Omega-3-acid ethyl esters Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Omega-3-acid ethyl esters Rhabdomyolysis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Omega-3-acid ethyl esters Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Omega-3-acid ethyl esters Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Omeprazole Abdominal distension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Abdominal pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Abdominal pain upper 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Abnormal dreams 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Omeprazole Aggression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Agitation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Agranulocytosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Omeprazole Alanine aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Omeprazole Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Omeprazole Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Omeprazole Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Omeprazole Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Omeprazole Angioedema 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Apathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Omeprazole Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Back pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Blood creatinine increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Omeprazole Blood disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Bone disorder 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Omeprazole Bronchospasm 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Chest pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Cholestasis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Omeprazole Clostridium difficile colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Omeprazole Confusional state 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Omeprazole Constipation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Cough 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Omeprazole Decreased appetite 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Dermatitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Diplopia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Omeprazole Discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Omeprazole Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Dry mouth 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Omeprazole Dry skin 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Omeprazole Dysaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Omeprazole Dysgeusia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Dyspepsia 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Omeprazole Dyspnoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Encephalopathy 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Omeprazole Epistaxis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Omeprazole Erectile dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Omeprazole Eructation 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Omeprazole Eye disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Omeprazole Eye irritation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Faeces discoloured 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Omeprazole Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Feeling abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Flatulence 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Omeprazole Fracture 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Omeprazole Gamma-glutamyltransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Omeprazole Gastritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Gastrointestinal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Gastrointestinal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Hallucination 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Omeprazole Hepatic necrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Omeprazole Hepatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Omeprazole Hepatocellular injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Omeprazole Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Hypersensitivity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Hypersensitivity vasculitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Omeprazole Hypocalcaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Omeprazole Hypoglycaemia 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Omeprazole Hypomagnesaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Omeprazole Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Omeprazole Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Irritable bowel syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Jaundice 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Omeprazole Leukocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Omeprazole Liver disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Malaise 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Mental disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Muscle spasms 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Muscular weakness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Musculoskeletal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Omeprazole Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Nausea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Necrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Omeprazole Nephrotic syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Omeprazole Oedema peripheral 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Oropharyngeal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Pain in extremity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Pain of skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Omeprazole Palpitations 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Pancreatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Omeprazole Pancytopenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Omeprazole Paraesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Petechiae 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Photosensitivity reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Omeprazole Pollakiuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Proteinuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Pruritus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Pyrexia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Omeprazole Rash 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Renal failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Omeprazole Renal impairment 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Shock 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Omeprazole Skin disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Omeprazole Sleep disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Somnolence 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Omeprazole Stevens-Johnson syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Omeprazole Stomatitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Swelling 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Omeprazole Tachycardia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Omeprazole Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Omeprazole Tinnitus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Toxic epidermal necrolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Omeprazole Tremor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Tubulointerstitial nephritis 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Omeprazole Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Omeprazole Vertigo 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Vision blurred 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Omeprazole Visual impairment 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Omeprazole Vomiting 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Omeprazole Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Omeprazole magnesium Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Omeprazole magnesium Anaphylactic reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Omeprazole magnesium Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Omeprazole magnesium Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Omeprazole magnesium Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Omeprazole magnesium Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Omeprazole magnesium Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Omeprazole magnesium Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Omeprazole magnesium Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Omeprazole magnesium Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Omeprazole magnesium Irritable bowel syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Omeprazole magnesium Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Omeprazole magnesium Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Omeprazole magnesium Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Omeprazole magnesium Pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Omeprazole magnesium Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Omeprazole magnesium Pancytopenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Omeprazole magnesium Tubulointerstitial nephritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Omeprazole magnesium Urinary tract infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Omeprazole magnesium Vomiting 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ondansetron Abdominal distension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Abdominal pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Acute coronary syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Acute respiratory failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Agranulocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ondansetron Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Anxiety 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron Appendicitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Arrhythmia 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Asthenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Asthma 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron Ataxia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Atrial fibrillation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ondansetron Atrial septal defect 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron Atrioventricular block 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ondansetron Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Brain oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Cardiac arrest 1.0 1.0 0.0 0.0 1.0 0.0 0.0 Ondansetron Cardiac disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Cardiac failure 1.0 1.0 0.0 0.0 1.0 0.0 0.0 Ondansetron Cardiac murmur 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Ondansetron Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Cardiogenic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Cardiomegaly 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron Cardiovascular disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ondansetron Cerebral haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Cerebrovascular accident 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ondansetron Chest discomfort 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ondansetron Chest pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ondansetron Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Constipation 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron Cough 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron Cyanosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Deafness 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Dehydration 0.0 0.0 1.0 0.0 1.0 0.0 0.0 Ondansetron Depressed mood 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ondansetron Diarrhoea 0.0 0.0 1.0 0.0 1.0 0.0 0.0 Ondansetron Discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ondansetron Disturbance in attention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ondansetron Drug hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ondansetron Dyskinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ondansetron Dysphonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Dyspnoea 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Ondansetron Dystonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Ear infection 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron Ear pain 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Emotional distress 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron Encephalopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Epistaxis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Failure to thrive 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron Febrile neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Feeling cold 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Flatulence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ondansetron Flushing 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron Foetal growth restriction 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Gastrooesophageal reflux disease 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron Generalised tonic-clonic seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ondansetron Heart rate increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ondansetron Hyperhidrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Hyperventilation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ondansetron Hypocalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Hypoglycaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Hyponatraemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Hypoxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Jaundice 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron Laryngospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Left ventricular dysfunction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Lung disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Lymphadenopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Maternal drugs affecting foetus 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron Metabolic acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Migraine 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ondansetron Nasal congestion 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Nervousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Obstructive airways disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Oropharyngeal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ondansetron Otitis media 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron Oxygen saturation decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Pain 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron Palpitations 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Pleural effusion 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Pneumonia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Posterior reversible encephalopathy syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron Premature delivery 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ondansetron Pruritus 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Pyrexia 0.0 0.0 1.0 0.0 1.0 0.0 0.0 Ondansetron Rash erythematous 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Respiratory depression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Respiratory disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Respiratory distress 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Restlessness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Rhinorrhoea 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Sinus bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Sinus tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Sleep apnoea syndrome 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron Somnolence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ondansetron Speech disorder 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Ondansetron Staphylococcal infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Status epilepticus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Stevens-Johnson syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Stress 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Suicidal ideation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Suicide attempt 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Supraventricular tachycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Syncope 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Tachycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Tachypnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Torsade de pointes 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Toxic epidermal necrolysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Upper respiratory tract infection 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Vaginal haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Ventricular arrhythmia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Ventricular extrasystoles 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Ventricular fibrillation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Ventricular tachycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron Vertigo 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Ondansetron Viral infection 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ondansetron Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ondansetron Vomiting 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ondansetron Wheezing 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Ondansetron hydrochloride Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron hydrochloride Angioedema 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron hydrochloride Anxiety 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron hydrochloride Bradycardia 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron hydrochloride Bronchospasm 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron hydrochloride Cardio-respiratory arrest 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron hydrochloride Chest pain 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Ondansetron hydrochloride Chills 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron hydrochloride Constipation 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron hydrochloride Death 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron hydrochloride Diarrhoea 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron hydrochloride Dizziness 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Ondansetron hydrochloride Dyspnoea 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron hydrochloride Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ondansetron hydrochloride Fatigue 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron hydrochloride Headache 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron hydrochloride Hiccups 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron hydrochloride Hypersensitivity 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron hydrochloride Hypokalaemia 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Ondansetron hydrochloride Hypotension 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Ondansetron hydrochloride Hypoxia 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron hydrochloride Laryngeal oedema 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron hydrochloride Malaise 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron hydrochloride Pruritus 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Ondansetron hydrochloride Pyrexia 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron hydrochloride Rash 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron hydrochloride Shock 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron hydrochloride Somnolence 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron hydrochloride Tachycardia 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron hydrochloride Urinary retention 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ondansetron hydrochloride Urticaria 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Oritavancin Anaphylactic reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oritavancin Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oritavancin Chills 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oritavancin Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oritavancin Dyspnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oritavancin Erythema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oritavancin Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oritavancin Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oritavancin Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oritavancin Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oritavancin Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oritavancin Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Orlistat Abdominal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Orlistat Acute hepatic failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Orlistat Acute kidney injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Orlistat Coagulopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Orlistat Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Orlistat Diarrhoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Orlistat Diverticulitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Orlistat Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Orlistat Haematochezia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Orlistat Headache 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Orlistat Menopausal symptoms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Orlistat Nephrolithiasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Orlistat Pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Orlistat Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Orlistat Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Orlistat Rectal haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Orlistat Renal failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Orlistat Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oseltamivir Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oseltamivir Atrial septal defect 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Oseltamivir Bradycardia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oseltamivir Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oseltamivir Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oseltamivir Drug resistance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oseltamivir Dyspnoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oseltamivir Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oseltamivir Foetal death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oseltamivir Hypoxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oseltamivir Influenza 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Oseltamivir Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oseltamivir Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oseltamivir Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oseltamivir Stevens-Johnson syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oseltamivir Supraventricular tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oseltamivir Tachypnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oseltamivir Thrombocytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oseltamivir phosphate Agitation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oseltamivir phosphate Altered state of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oseltamivir phosphate Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oseltamivir phosphate Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oseltamivir phosphate Asthma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oseltamivir phosphate Confusional state 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oseltamivir phosphate Delirium 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oseltamivir phosphate Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oseltamivir phosphate Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oseltamivir phosphate Hallucination 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oseltamivir phosphate Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oseltamivir phosphate Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oseltamivir phosphate Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oseltamivir phosphate Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oseltamivir phosphate Nightmare 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oseltamivir phosphate Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Oseltamivir phosphate Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oseltamivir phosphate Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oseltamivir phosphate Swelling face 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oseltamivir phosphate Swollen tongue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oseltamivir phosphate Toxic epidermal necrolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oseltamivir phosphate Urticaria 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Osimertinib Abdominal discomfort 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Acute kidney injury 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Acute myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Acute respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Alanine aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Altered state of consciousness 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Osimertinib Anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Osimertinib Arrhythmia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Aspartate aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Aspiration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Asthenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Asthma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Atelectasis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Atrial fibrillation 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Back pain 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Osimertinib Blood alkaline phosphatase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Blood pressure decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Blood sodium decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Cardiac disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Cardiac failure acute 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Cardiac failure congestive 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Osimertinib Cardiac tamponade 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Cardiotoxicity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Cardiovascular disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Cerebral infarction 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Osimertinib Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Chest pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Cognitive disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Constipation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Cough 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Osimertinib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Deep vein thrombosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Dehydration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Depressed level of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Diarrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Osimertinib Disseminated intravascular coagulation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Drug eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Drug hypersensitivity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Drug intolerance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Drug resistance 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Osimertinib Dry skin 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Dysgeusia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Dyspepsia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Dysphagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Dysphonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Ejection fraction decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Osimertinib Electrocardiogram QT prolonged 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Osimertinib Embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Enterocolitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Epistaxis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Erythema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Fatigue 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Febrile neutropenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Feeling abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Femur fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Gait disturbance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Gastrointestinal disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Haemoglobin decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Haemoptysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Headache 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Heart rate increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Hepatotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Osimertinib Herpes zoster 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Hyperkalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Hypoaesthesia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Hypocalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Hypokalaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Hyponatraemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Hypotension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Hypoxia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Inappropriate antidiuretic hormone secretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Interstitial lung disease 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Joint swelling 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Liver disorder 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Loss of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Lung disorder 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Lung infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Lymphocyte count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Osimertinib Lymphopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Osimertinib Malaise 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Osimertinib Memory impairment 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Metastases to central nervous system 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Metastases to liver 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Osimertinib Muscular weakness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Myalgia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Myocardial infarction 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Osimertinib Nausea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Osimertinib Oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Oedema peripheral 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Oxygen saturation decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Pain in extremity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Pericardial effusion 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Peripheral swelling 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Platelet count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Pleural effusion 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Pneumocystis jirovecii pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Pneumonia aspiration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Pneumonia bacterial 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Pneumonitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Pneumothorax 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Pulmonary alveolar haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Pulmonary embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Pyrexia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Rash 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Rash pruritic 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Renal disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Renal impairment 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Respiratory distress 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Seizure 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Osimertinib Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Skin ulcer 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Osimertinib Somnolence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Stevens-Johnson syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Stress cardiomyopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Subdural haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Tachycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Thrombocytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Thrombosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Toxic epidermal necrolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Urinary tract infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Osimertinib Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Osimertinib Vomiting 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Osimertinib Weight decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Osimertinib White blood cell count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ospemifene Deep vein thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ospemifene Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ospemifene Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ospemifene Pulmonary embolism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ospemifene Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ospemifene Vaginal discharge 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ospemifene Vaginal haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxacillin sodium Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Abdominal discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Abdominal distension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Abdominal pain upper 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Acidosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Acute coronary syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Acute hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Acute myeloid leukaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Acute myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Acute pulmonary oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Acute respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Agitation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Agranulocytosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Altered state of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Amnesia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Anaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Anaphylactoid reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Angina pectoris 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Anuria 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Anxiety 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Aphasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxaliplatin Ascites 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Aspartate aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Asthenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Atrial fibrillation 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Back pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Bacteraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Blindness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxaliplatin Blood bilirubin increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Blood creatinine increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Blood lactate dehydrogenase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Blood pressure abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Blood pressure decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Blood pressure increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Blood urea increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Body temperature increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Bone marrow failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Bone pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Brain oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Bronchospasm 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Burning sensation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Candida infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Cardiac failure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Cardiac failure acute 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Cardiogenic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Cardiomyopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Cellulitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Cerebral infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Cerebrovascular accident 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Chest discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Chest pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Chills 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Cholangitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Cholestasis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Circulatory collapse 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Clostridium difficile colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Coagulopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Cold sweat 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Colitis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Colitis ischaemic 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Confusional state 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Oxaliplatin Constipation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Cyanosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Decreased appetite 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Deep vein thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Dehydration 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Delirium 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Depressed level of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Depression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Dermatitis allergic 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Diarrhoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Diplopia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxaliplatin Disease recurrence 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxaliplatin Disorientation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Disseminated intravascular coagulation 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Disturbance in attention 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Oxaliplatin Dizziness 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Oxaliplatin Drug hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxaliplatin Drug-induced liver injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Dry mouth 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Dry skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxaliplatin Dysaesthesia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Dysarthria 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Dysgeusia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Dyskinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Dyspepsia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Oxaliplatin Dysphagia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Dysphonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Dyspnoea 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Oxaliplatin Dyspnoea exertional 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Dysstasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Ejection fraction decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Electrocardiogram QT prolonged 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Electrolyte imbalance 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Encephalopathy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Enteritis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Enterocolitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Epilepsy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Epistaxis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Erythema 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Oxaliplatin Extrasystoles 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Eye swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxaliplatin Eyelid oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxaliplatin Face oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Febrile neutropenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Feeling abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Feeling hot 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Flatulence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Flushing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxaliplatin Gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Gastrooesophageal reflux disease 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Generalised tonic-clonic seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Haematemesis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Haematuria 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Haemoglobin decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Haemolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Haemolytic anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Haemoptysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Haemorrhagic stroke 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Haemorrhoids 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxaliplatin Headache 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Heart rate decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Heart rate increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Hemiparesis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Hepatic cirrhosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Hepatic enzyme increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Hepatic function abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Hepatic steatosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Hepatomegaly 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Hepatotoxicity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Herpes zoster 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Hiccups 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Hot flush 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Hyperbilirubinaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Hyperglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Hyperkalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Hypertensive crisis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Hyperthermia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxaliplatin Hypoaesthesia oral 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Hypocalcaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Hypokinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Hypomagnesaemia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxaliplatin Hyponatraemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Hypophagia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Hypothermia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Hypotonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Hypoxia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Ileus 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Immune system disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxaliplatin Immune thrombocytopenic purpura 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Inflammation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Influenza like illness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Interstitial lung disease 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Intestinal obstruction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Ischaemic stroke 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Jaundice 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Joint stiffness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Lacrimation increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxaliplatin Lactic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Large intestine perforation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Laryngeal oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Laryngospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Lip swelling 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Liver disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxaliplatin Liver injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Loss of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Lung disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Lung infection 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxaliplatin Lung infiltration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Lymphopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxaliplatin Malaise 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Melaena 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Mental disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Mental status changes 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Metabolic acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Metastases to liver 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Metastases to lung 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Miosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Mobility decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Mouth ulceration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Muscle rigidity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Muscle spasms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Muscular weakness 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Oxaliplatin Musculoskeletal stiffness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Myalgia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Oxaliplatin Myelodysplastic syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Myocardial ischaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Myocarditis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Nasopharyngitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Nausea 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Oxaliplatin Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Nephropathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Neurological symptom 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Neuropathy peripheral 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Oxaliplatin Neurotoxicity 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Oxaliplatin Neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 1.0 Oxaliplatin Neutrophil count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Ocular hyperaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxaliplatin Oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Oedema peripheral 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Oesophagitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Oropharyngeal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxaliplatin Oxygen saturation decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Pain in extremity 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Oxaliplatin Pallor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Palpitations 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Oxaliplatin Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Pancytopenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Paraesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Oxaliplatin Paraesthesia oral 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Peptic ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Peripheral ischaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Peritonitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Petechiae 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Pharyngeal oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Pharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Phlebitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxaliplatin Platelet count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Pleural effusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Pneumonitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Pneumothorax 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Pollakiuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxaliplatin Polyneuropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxaliplatin Posterior reversible encephalopathy syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Proctalgia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Prothrombin time prolonged 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Pruritus 0.0 1.0 0.0 0.0 0.0 1.0 1.0 Oxaliplatin Pruritus generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Pulmonary embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Pulmonary fibrosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Pulmonary hypertension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Purpura 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Rales 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Rash erythematous 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Rash generalised 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxaliplatin Rash papular 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Rash pruritic 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Rectal haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Renal impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Renal tubular necrosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Respiratory disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Respiratory distress 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Restlessness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Retching 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Rhabdomyolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Seizure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Sensory disturbance 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Sinus tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Sinusitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Skin disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxaliplatin Skin lesion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Skin reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxaliplatin Small intestinal obstruction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Speech disorder 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Stomatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Stress cardiomyopathy 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Swollen tongue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Syncope 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Tachypnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Throat irritation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Throat tightness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Tinnitus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Tongue disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Tongue oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Torsade de pointes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Toxic skin eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Treatment failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Tremor 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Troponin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Tumour lysis syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Unresponsive to stimuli 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Upper respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Urinary incontinence 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Urinary tract infection 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Oxaliplatin Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Vascular purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Ventricular fibrillation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Vertigo 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Vision blurred 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Weight decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin Weight increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxaliplatin Wheezing 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxaliplatin White blood cell count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxazepam Aggression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxazepam Akathisia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxazepam Asphyxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxazepam Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxazepam Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxazepam Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxazepam Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxazepam Depressed level of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxazepam Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxazepam Drug dependence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxazepam Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxazepam Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxazepam Intentional self-injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxazepam Loss of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxazepam Mydriasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxazepam Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxazepam Suicidal ideation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxazepam Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxazepam Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxcarbazepine Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxcarbazepine Agranulocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxcarbazepine Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxcarbazepine Arrhythmia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxcarbazepine Asthenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxcarbazepine Atrial septal defect 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Oxcarbazepine Back pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxcarbazepine Balance disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxcarbazepine Blindness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Oxcarbazepine Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxcarbazepine Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxcarbazepine Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxcarbazepine Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxcarbazepine Cognitive disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxcarbazepine Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxcarbazepine Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxcarbazepine Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxcarbazepine Crying 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxcarbazepine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxcarbazepine Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxcarbazepine Depression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxcarbazepine Dermatitis exfoliative 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxcarbazepine Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxcarbazepine Diplopia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxcarbazepine Disorientation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxcarbazepine Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxcarbazepine Drug dependence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxcarbazepine Drug eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxcarbazepine Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxcarbazepine Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxcarbazepine Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxcarbazepine Encephalopathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxcarbazepine Epilepsy 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Oxcarbazepine Erythema multiforme 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxcarbazepine Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxcarbazepine Fear 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxcarbazepine Feeling abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxcarbazepine Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxcarbazepine Gastrointestinal disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxcarbazepine Generalised tonic-clonic seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxcarbazepine Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxcarbazepine Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxcarbazepine Hyponatraemia 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Oxcarbazepine Hypotonia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxcarbazepine Inappropriate antidiuretic hormone secretion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxcarbazepine Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxcarbazepine Intentional self-injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxcarbazepine Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxcarbazepine Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxcarbazepine Memory impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxcarbazepine Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxcarbazepine Mood altered 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxcarbazepine Movement disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxcarbazepine Muscle spasms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxcarbazepine Nausea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxcarbazepine Nervousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxcarbazepine Nystagmus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxcarbazepine Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxcarbazepine Pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Oxcarbazepine Peripheral swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxcarbazepine Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxcarbazepine Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxcarbazepine Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxcarbazepine Rash erythematous 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxcarbazepine Renal failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxcarbazepine Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxcarbazepine Seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxcarbazepine Sepsis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxcarbazepine Septic shock 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxcarbazepine Skin exfoliation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxcarbazepine Somnolence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxcarbazepine Sopor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxcarbazepine Speech disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxcarbazepine Status epilepticus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxcarbazepine Stevens-Johnson syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxcarbazepine Suicidal ideation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxcarbazepine Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxcarbazepine Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxcarbazepine Toxic epidermal necrolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxcarbazepine Unevaluable event 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxcarbazepine Urinary incontinence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxcarbazepine Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxcarbazepine Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxcarbazepine Weight decreased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Oxybutynin Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxybutynin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxybutynin Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxybutynin Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxybutynin Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxybutynin Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxybutynin Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxybutynin Urinary retention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxybutynin chloride Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxybutynin chloride Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxybutynin chloride Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxybutynin chloride Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxybutynin chloride Urinary retention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxycodone Abdominal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone Abdominal distension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Abdominal pain upper 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone Acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Acute kidney injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Acute respiratory failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Aggression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxycodone Agitation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Alanine aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Altered state of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Amnesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone Apnoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxycodone Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone Blindness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Oxycodone Bradycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Brain injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Brain oedema 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Oxycodone Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Cardiac failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Catatonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Cerebral haemorrhage 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Oxycodone Chest discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxycodone Circulatory collapse 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Coagulopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxycodone Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Decubitus ulcer 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Oxycodone Deep vein thrombosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxycodone Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Delusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Depressed level of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Disorientation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Disseminated intravascular coagulation 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Oxycodone Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone Drug abuse 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Drug dependence 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Oxycodone Drug interaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Drug withdrawal syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Emotional distress 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Oxycodone Encephalitis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Oxycodone Faecaloma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone Gallbladder disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Hepatic function abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Hyperaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Hyperkalaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Hypoglycaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Hypothermia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Hypoxia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Ileus paralytic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Ill-defined disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxycodone Intentional self-injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Irritable bowel syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone Joint swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxycodone Leukocytosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Loss of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Mania 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Mental impairment 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Metabolic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Migraine 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxycodone Miosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Multiple organ dysfunction syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Oxycodone Mydriasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Nasopharyngitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxycodone Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Nervous system disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Oxygen saturation decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Oxycodone Pallor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Pancreatitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Pneumonia aspiration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxycodone Psychotic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Pulmonary congestion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Pulmonary embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Pulmonary fibrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Pulmonary hypertension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Rash 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone Renal impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Respiratory depression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Respiratory distress 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Restlessness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Retching 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Rhabdomyolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Sedation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Sepsis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Septic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Serotonin syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Sinusitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxycodone Sleep apnoea syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxycodone Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Speech disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Staphylococcal infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Stomatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxycodone Stress cardiomyopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Subdural haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxycodone Swollen tongue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Tachycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Thrombocytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Unevaluable event 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Unresponsive to stimuli 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Ventricular arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxycodone Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Weight decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Oxycodone Wheezing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxycodone hydrochloride Abdominal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Affect lability 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Agitation 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Amnesia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Oxycodone hydrochloride Anaemia 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone hydrochloride Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Oxycodone hydrochloride Apnoea 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Arthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Asthenia 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Back pain 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Bone pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Bronchitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone hydrochloride Cardiac failure 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Chest pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Chills 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Choking 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxycodone hydrochloride Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone hydrochloride Confusional state 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Constipation 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Cough 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Death 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Decreased appetite 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Deep vein thrombosis 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Dehydration 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Dental caries 0.0 0.0 0.0 1.0 1.0 0.0 1.0 Oxycodone hydrochloride Depression 1.0 0.0 0.0 1.0 0.0 0.0 1.0 Oxycodone hydrochloride Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Oxycodone hydrochloride Dry skin 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Dysphagia 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Dysphonia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Dyspnoea 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Dysuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Epistaxis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxycodone hydrochloride Erectile dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Oxycodone hydrochloride Euphoric mood 1.0 0.0 0.0 1.0 0.0 0.0 1.0 Oxycodone hydrochloride Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Gastritis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxycodone hydrochloride Gastrointestinal disorder 0.0 0.0 0.0 1.0 1.0 0.0 1.0 Oxycodone hydrochloride Gout 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Haematuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Haemorrhage 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Hallucination 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Headache 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Oxycodone hydrochloride Hyperaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Hyperglycaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxycodone hydrochloride Hyperhidrosis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Oxycodone hydrochloride Hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxycodone hydrochloride Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone hydrochloride Hypotonia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Ileus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxycodone hydrochloride Infection 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Influenza 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Injury 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Oxycodone hydrochloride Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Oxycodone hydrochloride Libido decreased 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Oxycodone hydrochloride Lung disorder 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Malaise 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Oxycodone hydrochloride Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Muscle twitching 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Nausea 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Oxycodone hydrochloride Neck pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Nervousness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Oxycodone hydrochloride Neuralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Oedema 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Oedema peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Oxycodone hydrochloride Palpitations 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Oxycodone hydrochloride Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Personality disorder 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Pharyngitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxycodone hydrochloride Photosensitivity reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone hydrochloride Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Pyrexia 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Rash 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxycodone hydrochloride Respiratory depression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone hydrochloride Retching 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Seizure 1.0 0.0 0.0 1.0 1.0 0.0 0.0 Oxycodone hydrochloride Sepsis 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Shock 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Sinusitis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Oxycodone hydrochloride Somnolence 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Speech disorder 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Oxycodone hydrochloride Stomatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone hydrochloride Stupor 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxycodone hydrochloride Syncope 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Tachycardia 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Thirst 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxycodone hydrochloride Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Tremor 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Oxycodone hydrochloride Urinary retention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxycodone hydrochloride Vertigo 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Visual impairment 0.0 0.0 0.0 1.0 1.0 0.0 1.0 Oxycodone hydrochloride Vomiting 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Oxycodone hydrochloride Withdrawal syndrome 1.0 0.0 0.0 1.0 0.0 0.0 1.0 Oxygen Acute pulmonary oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxygen Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxygen Chronic obstructive pulmonary disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxygen Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxygen Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxygen Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxygen Hypoxia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxygen Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxygen Oxygen saturation decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxygen Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxygen Pneumothorax 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxygen Pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxygen Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxygen Respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Oxygen Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxymorphone Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxymorphone Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Oxymorphone hydrochloride Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Oxytocin Haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Oxytocin Hyponatraemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paclitaxel Abdominal discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Abdominal pain 1.0 1.0 1.0 0.0 0.0 1.0 0.0 Paclitaxel Abdominal pain lower 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Abscess 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Acute coronary syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Acute generalised exanthematous pustulosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Acute myeloid leukaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Acute myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Acute pulmonary oedema 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Acute respiratory failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Ageusia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paclitaxel Aggression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Agitation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Agranulocytosis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Alanine aminotransferase increased 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Paclitaxel Alopecia 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Paclitaxel Altered state of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Amnesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Anaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Anal incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Paclitaxel Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Anaphylactoid reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Angioedema 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paclitaxel Angiopathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paclitaxel Anxiety 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Aphasia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Appendicitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Arthralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paclitaxel Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Aspartate aminotransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Aspiration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Asthenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Ataxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Atelectasis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Atrial fibrillation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Atrioventricular block 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Back pain 0.0 1.0 0.0 0.0 0.0 1.0 1.0 Paclitaxel Bacteraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Balance disorder 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Paclitaxel Blood albumin decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Blood alkaline phosphatase increased 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Paclitaxel Blood bilirubin increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Blood creatinine increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Blood lactate dehydrogenase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Blood magnesium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Blood pressure decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Blood pressure increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Blood sodium decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Bone marrow failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Breast cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paclitaxel C-reactive protein increased 1.0 0.0 1.0 0.0 1.0 0.0 0.0 Paclitaxel Cachexia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Candida infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Cardiac disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Cardiac failure acute 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Cardiac failure congestive 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Cardiogenic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Cardiomyopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Cardiotoxicity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Cardiovascular disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Cellulitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Cerebral infarction 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Paclitaxel Cerebrovascular accident 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Chest discomfort 0.0 1.0 0.0 0.0 0.0 1.0 1.0 Paclitaxel Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Chills 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Cholangitis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Cholecystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Chronic obstructive pulmonary disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Circulatory collapse 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Clostridium difficile colitis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Clostridium difficile infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Cold sweat 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Colitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Colitis ischaemic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Coma 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Confusional state 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Conjunctivitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paclitaxel Constipation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Cyanosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paclitaxel Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Decreased appetite 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Deep vein thrombosis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Dehydration 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Depressed level of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Depressed mood 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Diabetic ketoacidosis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Diarrhoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Diarrhoea haemorrhagic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Diplopia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paclitaxel Discomfort 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Disorientation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Disseminated intravascular coagulation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Disturbance in attention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paclitaxel Dizziness 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Paclitaxel Drug eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Drug hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Drug interaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Drug intolerance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Drug resistance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Drug-induced liver injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Dry mouth 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Dry throat 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Dysaesthesia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Dysarthria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Dyspepsia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Dyspnoea 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Paclitaxel Dyspnoea exertional 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Dysuria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Eating disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Electrolyte imbalance 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Encephalopathy 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Enterocolitis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Erythema 0.0 1.0 0.0 0.0 0.0 1.0 1.0 Paclitaxel Erythema multiforme 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paclitaxel Eyelid oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paclitaxel Facial paralysis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paclitaxel Failure to thrive 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Fatigue 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Febrile neutropenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Feeling abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Feeling hot 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Paclitaxel Femur fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Flatulence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Flushing 0.0 1.0 0.0 0.0 0.0 1.0 1.0 Paclitaxel Foetal growth restriction 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Paclitaxel Full blood count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Fungal infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paclitaxel Gamma-glutamyltransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Gastric cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Gastrointestinal haemorrhage 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Generalised oedema 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Paclitaxel Generalised tonic-clonic seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Haematemesis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Haemodynamic instability 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Haemoglobin decreased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Haemoptysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Headache 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Heart rate increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Hemiparesis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Hepatic cirrhosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Hepatic encephalopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Hepatic enzyme increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Hepatic function abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Hepatitis acute 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Hepatocellular injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Hepatomegaly 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Hepatotoxicity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Hiccups 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Hip fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Hot flush 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Paclitaxel Hydronephrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Hypercalcaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Hyperglycaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Hyperkalaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Hypernatraemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Hyperpyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Hypertension 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Paclitaxel Hypertensive crisis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Hypertriglyceridaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paclitaxel Hypocalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Hypoglycaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Hypomagnesaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Hypotension 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Paclitaxel Hypothermia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Hypothyroidism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Hypoxia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Ileus 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Influenza like illness 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Insomnia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Interstitial lung disease 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Intestinal obstruction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Intestinal perforation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Ischaemic stroke 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Jaundice 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Joint swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Keratitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paclitaxel Lacrimation increased 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Paclitaxel Large intestine perforation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Laryngeal oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paclitaxel Laryngospasm 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Paclitaxel Left ventricular dysfunction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Leukocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Leukopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Liver function test abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Liver injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Lung disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Lung infection 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Lung infiltration 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Lymphadenopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Lymphocyte count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Malaise 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Malignant melanoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Malnutrition 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Melaena 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Mental status changes 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Metastases to central nervous system 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Metastases to liver 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Metastases to lung 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Micturition urgency 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Migraine 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Mouth ulceration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Mucosal inflammation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Muscle spasms 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paclitaxel Muscular weakness 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Musculoskeletal chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Musculoskeletal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Musculoskeletal disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paclitaxel Musculoskeletal stiffness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paclitaxel Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Myocardial ischaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Nail disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paclitaxel Nasal congestion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Nausea 1.0 0.0 1.0 0.0 0.0 1.0 0.0 Paclitaxel Neck pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Nephropathy toxic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paclitaxel Nervous system disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Neuropathy peripheral 1.0 0.0 0.0 1.0 0.0 0.0 1.0 Paclitaxel Neurotoxicity 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Paclitaxel Neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Neutrophil count decreased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Oedema peripheral 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Oesophagitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Oliguria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Oral candidiasis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Oropharyngeal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Orthostatic hypotension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Osteonecrosis of jaw 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paclitaxel Oxygen saturation decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Pallor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Palpitations 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Pancreatic carcinoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Pancreatitis acute 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Pancytopenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Paclitaxel Pericardial effusion 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Pericarditis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Peripheral sensory neuropathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Peritonitis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Photosensitivity reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paclitaxel Platelet count decreased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Pleural effusion 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Pneumocystis jirovecii pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Pneumonia aspiration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Pneumonitis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Pneumothorax 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Polyneuropathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paclitaxel Posterior reversible encephalopathy syndrome 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Premature baby 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Premature delivery 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paclitaxel Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Productive cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Proteinuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paclitaxel Pruritus 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Paclitaxel Pseudomembranous colitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Pulmonary embolism 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Pulmonary fibrosis 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Paclitaxel Pulmonary haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Pulmonary hypertension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Pyrexia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Rales 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Rash erythematous 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Rash pruritic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paclitaxel Raynaud's phenomenon 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Renal disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Renal failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Respiratory arrest 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Respiratory depression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Respiratory disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Respiratory distress 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Respiratory tract infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Restlessness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Retching 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Rhabdomyolysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Rhinitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paclitaxel Seizure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Sepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Sinus bradycardia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paclitaxel Sinus tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Sinusitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Skin discolouration 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Skin exfoliation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Skin infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Skin lesion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Sleep disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Small intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Staphylococcal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Status epilepticus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Stevens-Johnson syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Stomatitis 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Paclitaxel Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Supraventricular tachycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Swelling face 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Syncope 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Tachycardia 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Paclitaxel Tachypnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Throat irritation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Throat tightness 0.0 1.0 0.0 0.0 0.0 1.0 1.0 Paclitaxel Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Thrombophlebitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Toxic epidermal necrolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Toxic skin eruption 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paclitaxel Transaminases increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Treatment failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Tremor 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Tumour lysis syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Unevaluable event 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Unresponsive to stimuli 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Upper respiratory tract infection 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Urinary incontinence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Urosepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Ventricular extrasystoles 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Ventricular fibrillation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel Vision blurred 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paclitaxel Visual acuity reduced 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Paclitaxel Vomiting 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Paclitaxel White blood cell count decreased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Abdominal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Abdominal distension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Abdominal pain upper 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Acute hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Acute kidney injury 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Acute myeloid leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Acute respiratory distress syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Acute respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Alanine aminotransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Anaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Angioedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Aphthous ulcer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Arrhythmia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Arthralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Arthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Aspartate aminotransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Asthenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Asthma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Back pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Bacteraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Blindness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Blister 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Blood alkaline phosphatase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Blood bilirubin increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Blood cholesterol increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Blood count abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Blood creatinine increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Blood glucose decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Blood potassium increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Blood pressure decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Bone marrow failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Bone pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Breast cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Breast pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Cachexia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Candida infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Palbociclib Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Cardiac disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Cardiac failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Carpal tunnel syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Cerebral infarction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Cerebrovascular accident 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Chest discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Choking 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Palbociclib Chronic kidney disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Chronic obstructive pulmonary disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Clostridium difficile infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Colitis ischaemic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Coma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Confusional state 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Conjunctivitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Constipation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Contusion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Crohn's disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Crying 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Cystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Decubitus ulcer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Dementia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Depressed level of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Depressed mood 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Diarrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Disease recurrence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Disorientation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Disseminated intravascular coagulation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Dry eye 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Dry skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Dysgeusia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Ear disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Ear pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Eating disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Electrocardiogram QT prolonged 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Electrolyte imbalance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Emotional disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Enteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Epistaxis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Eructation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Erythema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Eye disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Palbociclib Eye haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Eye pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Facial paralysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Febrile neutropenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Feeding disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Feeling abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Feeling cold 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Femur fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Flatulence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Frequent bowel movements 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Full blood count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Gamma-glutamyltransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Gastrooesophageal reflux disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Gingival bleeding 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Glossodynia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Granulocytopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Haematemesis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Haematochezia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Haematocrit decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Haemoglobin decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Haemorrhoids 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Hepatic cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Hepatic cirrhosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Hepatic function abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Hepatic steatosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Hepatocellular injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Hepatotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Hernia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Hip fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Hot flush 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Hypercalcaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Hyperhidrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Hyperlipidaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Hyperthyroidism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Hypoaesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Hypocalcaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Hypoglycaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Hyponatraemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Hypothyroidism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Hypoxia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Ileus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Increased appetite 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Interstitial lung disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Intestinal perforation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Irritability 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Jaundice 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Joint stiffness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Laboratory test abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Lacrimation increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Laryngitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Lethargy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Leukaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Leukopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Lip swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Liver disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Liver function test abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Liver function test increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Liver injury 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Localised infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Lower respiratory tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Lung disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Lung infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Lung neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Lymphoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Lymphopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Malignant neoplasm progression 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Memory impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Mental impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Migraine 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Mobility decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Palbociclib Mood swings 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Mouth ulceration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Mucosal inflammation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Muscle spasms 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Musculoskeletal chest pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Musculoskeletal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Palbociclib Musculoskeletal stiffness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Nasal congestion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Nasopharyngitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Nausea 0.0 0.0 0.0 0.0 0.0 1.0 1.0 Palbociclib Neck pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Nephrolithiasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Nervousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Neuralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Neutropenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Neutrophil count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Night sweats 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Nodule 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Oesophagitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Oral candidiasis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Oral pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Oropharyngeal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Osteonecrosis of jaw 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Oxygen saturation decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Pain in extremity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Pain in jaw 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Pallor 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Pancytopenia 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Panic attack 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Paraesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Paraesthesia oral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Parosmia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Pelvic pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Pericardial effusion 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Palbociclib Peripheral coldness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Pharyngeal oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Photosensitivity reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Platelet count decreased 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Pleural effusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Pneumocystis jirovecii pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Pneumonitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Polyneuropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Productive cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Pulmonary embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Pulmonary mass 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Rash pruritic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Red blood cell count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Renal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Respiratory disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Respiratory distress 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Respiratory tract congestion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Rhabdomyolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Rheumatoid arthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Rhinorrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Sciatica 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Palbociclib Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Sepsis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Sinusitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Skin cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Skin exfoliation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Skin lesion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Sleep disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Small intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Staphylococcal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Stomatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Stress 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Subarachnoid haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Suicidal ideation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Swelling 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Swollen tongue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Tenderness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Tendonitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Throat irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Thrombocytopenia 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Tinnitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Tooth abscess 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Toothache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Unevaluable event 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Unresponsive to stimuli 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Upper respiratory tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Urosepsis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palbociclib Varicose vein 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Venous thrombosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Visual acuity reduced 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Palbociclib Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Vomiting 1.0 0.0 1.0 0.0 0.0 1.0 0.0 Palbociclib Weight decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Palbociclib Wheezing 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Palbociclib White blood cell count decreased 0.0 0.0 0.0 0.0 0.0 1.0 1.0 Paliperidone Aggression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paliperidone Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paliperidone Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paliperidone Arrhythmia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paliperidone Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paliperidone Atrioventricular block first degree 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paliperidone Blood glucose increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paliperidone Catatonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paliperidone Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paliperidone Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paliperidone Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paliperidone Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paliperidone Deep vein thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paliperidone Delusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paliperidone Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paliperidone Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paliperidone Dyspnoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paliperidone Dystonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paliperidone Electrocardiogram QT prolonged 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paliperidone Emotional disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paliperidone Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paliperidone Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paliperidone Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paliperidone Galactorrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paliperidone Gynaecomastia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paliperidone Hallucination 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paliperidone Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paliperidone Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paliperidone Hypothermia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paliperidone Intentional self-injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paliperidone Irritability 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paliperidone Mania 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paliperidone Mental disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paliperidone Muscle rigidity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paliperidone Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paliperidone Neuroleptic malignant syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paliperidone Obesity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paliperidone Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paliperidone Paranoia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paliperidone Parkinsonism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paliperidone Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paliperidone Psychotic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paliperidone Pulmonary embolism 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Paliperidone Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paliperidone Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paliperidone Sluggishness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paliperidone Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paliperidone Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paliperidone Tardive dyskinesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paliperidone Thinking abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paliperidone Tremor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paliperidone Vomiting 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paliperidone Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paliperidone palmitate Abdominal pain upper 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paliperidone palmitate Agitation 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Paliperidone palmitate Akathisia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Paliperidone palmitate Amenorrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paliperidone palmitate Anxiety 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Paliperidone palmitate Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paliperidone palmitate Cognitive disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paliperidone palmitate Constipation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paliperidone palmitate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paliperidone palmitate Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paliperidone palmitate Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paliperidone palmitate Dysarthria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paliperidone palmitate Dyskinesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paliperidone palmitate Dysphagia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paliperidone palmitate Dystonia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paliperidone palmitate Erectile dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paliperidone palmitate Erythema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paliperidone palmitate Extrapyramidal disorder 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Paliperidone palmitate Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paliperidone palmitate Gynaecomastia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paliperidone palmitate Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paliperidone palmitate Hypertension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paliperidone palmitate Hypertonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paliperidone palmitate Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Paliperidone palmitate Increased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paliperidone palmitate Lethargy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paliperidone palmitate Muscle rigidity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paliperidone palmitate Muscle spasms 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paliperidone palmitate Musculoskeletal stiffness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paliperidone palmitate Myalgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paliperidone palmitate Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paliperidone palmitate Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paliperidone palmitate Neuroleptic malignant syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Paliperidone palmitate Nightmare 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paliperidone palmitate Pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paliperidone palmitate Parkinsonism 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paliperidone palmitate Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paliperidone palmitate Psychomotor hyperactivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paliperidone palmitate Rash 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paliperidone palmitate Restlessness 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Paliperidone palmitate Salivary hypersecretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paliperidone palmitate Sedation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paliperidone palmitate Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paliperidone palmitate Sleep disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paliperidone palmitate Somnolence 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paliperidone palmitate Swollen tongue 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Paliperidone palmitate Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paliperidone palmitate Tardive dyskinesia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Paliperidone palmitate Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paliperidone palmitate Urinary incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paliperidone palmitate Urinary tract infection 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Paliperidone palmitate Vertigo 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paliperidone palmitate Vision blurred 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paliperidone palmitate Vomiting 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paliperidone palmitate Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Palonosetron hydrochloride Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Palonosetron hydrochloride Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pamidronate disodium Confusional state 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pamidronate disodium Constipation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pamidronate disodium Dyspnoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pamidronate disodium Hypokalaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pamidronate disodium Osteonecrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pamidronate disodium Osteonecrosis of jaw 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Panobinostat Anaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Panobinostat Asthenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Panobinostat Atrial fibrillation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Panobinostat Blood creatinine increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Panobinostat Bone marrow failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Panobinostat Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Panobinostat Confusional state 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Panobinostat Constipation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Panobinostat Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Panobinostat Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Panobinostat Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Panobinostat Diarrhoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Panobinostat Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Panobinostat Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Panobinostat Dyspnoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Panobinostat Fatigue 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Panobinostat Haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Panobinostat Infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Panobinostat Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Panobinostat Loss of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Panobinostat Malaise 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Panobinostat Malignant neoplasm progression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Panobinostat Nausea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Panobinostat Neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Panobinostat Palpitations 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Panobinostat Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Panobinostat Plasma cell myeloma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Panobinostat Platelet count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Panobinostat Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Panobinostat Pyrexia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Panobinostat Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Panobinostat Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Panobinostat Tachycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Panobinostat Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Panobinostat Vomiting 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Panobinostat Weight decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Panobinostat White blood cell count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Abdominal distension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Abdominal pain lower 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Abdominal pain upper 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Acute coronary syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Acute generalised exanthematous pustulosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Acute hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Acute kidney injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Acute myocardial infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Agitation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Agranulocytosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Altered state of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Amnesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Angina pectoris 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Angioedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Anuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole Aphasia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Aphthous ulcer 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole Arthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole Arthropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Atrial fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Back pain 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Pantoprazole Blister 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Blood creatine phosphokinase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Blood creatinine increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Blood pressure decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Blood urine present 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole Body temperature increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Burning sensation 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole Bursitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole C-reactive protein increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Candida infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Cardiac disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Cardiac failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Cardiovascular disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Choking 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole Cholecystitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Cholestasis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Chromaturia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Chronic kidney disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole Circulatory collapse 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Clostridium difficile colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Clostridium difficile infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Coagulopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Cold sweat 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Confusional state 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Conjunctivitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Contusion 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole Crohn's disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole Cyanosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Deafness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Death 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Pantoprazole Decreased appetite 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Deep vein thrombosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Depressed level of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole Diarrhoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Disease recurrence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole Disorientation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Disseminated intravascular coagulation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Disturbance in attention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole Drug abuse 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Drug eruption 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Drug hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole Drug reaction with eosinophilia and systemic symptoms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Drug-induced liver injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole Duodenal ulcer 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Dyspepsia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole Dyspnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Eczema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Emotional distress 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Encephalopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Eye disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole Eye pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole Eyelid oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Face oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Faecaloma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole Femur fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Flatulence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Foetal growth restriction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Gastric cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole Gastroenteritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Generalised oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Gynaecomastia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Haematemesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Haematocrit decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole Haematoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Haemoglobin decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole Haemolytic anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Haemoptysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole Hepatic enzyme increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Hepatic function abnormal 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Hepatitis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Hepatitis acute 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Hepatitis cholestatic 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Hepatitis fulminant 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Hepatocellular injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Hepatotoxicity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Herpes zoster 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole Hip fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Hyperglycaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Hyperkalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole Hypersensitivity vasculitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Hypertonia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole Hypocalcaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Hypokinesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole Hypomagnesaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Hypophagia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Hypothermia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Hypothyroidism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole Hypoxia 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole Inappropriate antidiuretic hormone secretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Injection site reaction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole Iron deficiency anaemia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole Ischaemic stroke 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Jaundice 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Jaundice cholestatic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Joint swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole Lacrimation increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole Lethargy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Leukocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Leukopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Limb discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole Lip swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Localised infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Lung disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Lymphadenopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Melaena 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Mental disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole Metabolic acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Micturition disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Mobility decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole Mouth ulceration 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole Musculoskeletal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole Nausea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Nephrolithiasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole Nervous system disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Neuralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Neutropenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Nocturia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Nuchal rigidity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole Nystagmus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Oesophagitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Oral candidiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Oral discomfort 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Oropharyngeal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole Osteoarthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole Osteonecrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole Osteoporosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Pancytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Panic attack 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Paraesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Parkinson's disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole Pericardial effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Peritonitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Petechiae 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Pharyngitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Polyneuropathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole Premature baby 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Pantoprazole Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Productive cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Pruritus generalised 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Pseudomembranous colitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Psoriasis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole Purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Rash generalised 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Rash macular 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Rash pustular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Rectal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Red blood cell count decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole Renal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole Renal impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Respiratory distress 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Restless legs syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole Restlessness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Rheumatoid arthritis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pantoprazole Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Sinusitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Skin disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Skin exfoliation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Skin lesion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Skin ulcer 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Sleep disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Sopor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Speech disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Spinal compression fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Staphylococcal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Stevens-Johnson syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Tenderness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole Tendonitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole Thirst 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Thrombocytopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Tongue oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole Toxic epidermal necrolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Toxic skin eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Transaminases increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Treatment failure 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole Troponin increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Tubulointerstitial nephritis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Unresponsive to stimuli 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Upper gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Urosepsis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole Vascular purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Vertigo 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole Weight decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole Wheezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole White blood cell count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole sodium Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole sodium Agranulocytosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole sodium Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole sodium Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole sodium Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole sodium Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole sodium Clostridium difficile colitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole sodium Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole sodium Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole sodium Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole sodium Diarrhoea 0.0 0.0 1.0 0.0 0.0 1.0 0.0 Pantoprazole sodium Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole sodium Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole sodium Face oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole sodium Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pantoprazole sodium Flatulence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole sodium Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole sodium Headache 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pantoprazole sodium Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole sodium Hepatocellular injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole sodium Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole sodium Hypomagnesaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole sodium Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole sodium Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole sodium Leukopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole sodium Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole sodium Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole sodium Pancytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole sodium Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole sodium Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole sodium Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pantoprazole sodium Stevens-Johnson syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole sodium Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole sodium Toxic epidermal necrolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole sodium Tubulointerstitial nephritis 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Pantoprazole sodium Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pantoprazole sodium Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pantoprazole sodium Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Abdominal pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Abscess 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Acute myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Acute pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Asthenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Bacteraemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Blood pressure decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Bone pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Cardiac disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Cardiac failure congestive 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Cardiogenic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Cardiopulmonary failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Cardiovascular disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Cerebral ischaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Cerebrovascular disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Chest pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Chronic kidney disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Cough 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Decreased appetite 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Diabetes mellitus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Discomfort 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Disorientation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Dyspepsia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Epistaxis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Fatigue 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Feeling abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Femur fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Fluid overload 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Gait disturbance 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Paricalcitol Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Generalised oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Haemorrhagic stroke 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Headache 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Hepatic cirrhosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Hip fracture 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Paricalcitol Hypercalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Hyperkalaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Hypertension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Hypertensive crisis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Hypoaesthesia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Hypoglycaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Hypotension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Hypotonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Ischaemic stroke 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Loss of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Lung infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Malaise 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Malnutrition 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Mental disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Myocardial ischaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Necrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Neoplasm 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Nephropathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Pain in extremity 1.0 0.0 1.0 1.0 0.0 0.0 0.0 Paricalcitol Peritonitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Pleural effusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Prostate cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Pulmonary embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Pulmonary oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Pyrexia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Renal disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Renal impairment 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Respiratory disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Respiratory distress 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Respiratory tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Seizure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Skin ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Syncope 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Tachycardia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Tension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Unevaluable event 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Urinary tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Urosepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paricalcitol Vomiting 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paricalcitol Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Abdominal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Abdominal distension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Abdominal pain upper 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Abnormal dreams 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Accommodation disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Acne 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Acute kidney injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Affect lability 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Ageusia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Aggression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Agitation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Agranulocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Akathisia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Alanine aminotransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Altered state of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Amnesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Anger 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Angina pectoris 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Paroxetine Apathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Aphasia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Apnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Arthralgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Aspartate aminotransferase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Asthma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Atrial septal defect 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Paroxetine Blister 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Brain injury 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Brain oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Chills 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Confusional state 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Contusion 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Crying 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Cyanosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Decreased appetite 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Paroxetine Dehydration 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Delirium 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Delusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Depersonalisation/derealisation disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Depressed level of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Depression 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Paroxetine Diarrhoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Disorientation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Paroxetine Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Paroxetine Drug abuse 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Drug dependence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Drug intolerance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Drug withdrawal syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Dysarthria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Dyskinesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Dysphagia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Dyspnoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Dystonia 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Paroxetine Dysuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Electrocardiogram abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Emotional distress 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Encephalopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Erectile dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Extrapyramidal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Eye pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Faecaloma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Paroxetine Fear 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Feeling abnormal 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Foetal death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Foetal growth restriction 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Paroxetine Fracture 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Gait disturbance 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Gastrointestinal disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Generalised tonic-clonic seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Haematemesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Haemorrhage intracranial 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Hallucination 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Headache 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Paroxetine Hemiplegia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Hepatic failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Hyperglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Paroxetine Hyperkalaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Hyperreflexia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Hypertonia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Hypoacusis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Hypoaesthesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Hypokalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Hypokinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Hypothermia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Immune thrombocytopenic purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Inappropriate antidiuretic hormone secretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Incontinence 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Paroxetine Intentional self-injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Irritability 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Paroxetine Left ventricular dysfunction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Lethargy 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Paroxetine Leukocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Libido decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Liver function test abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Lung disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Mania 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Melaena 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Menstrual disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Mental impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Migraine 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Mood altered 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Mood swings 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Mouth ulceration 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Movement disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Muscle spasms 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Muscle tightness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Musculoskeletal stiffness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Mydriasis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Myoclonus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Nervousness 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Neuroleptic malignant syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Nightmare 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Paroxetine Nocturia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Nystagmus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Oliguria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Pallor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Palpitations 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Panic attack 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Paroxetine Paraesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Paralysis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Paranoia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Parkinson's disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Parkinsonism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Parosmia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Photophobia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Pneumonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Pneumonia aspiration 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Paroxetine Pruritus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Psychomotor hyperactivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Psychotic disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Pulmonary embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Pulmonary fibrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Pyrexia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Renal impairment 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Restless legs syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Restlessness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Salivary hypersecretion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Sensory disturbance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Serotonin syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Sexual dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Sinus tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Skin discolouration 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Sleep disorder 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Paroxetine Somnolence 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Speech disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Status epilepticus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Stress 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Suicidal ideation 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Paroxetine Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Supraventricular extrasystoles 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Tachycardia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Tachypnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Tension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Thinking abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Throat tightness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Transaminases increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine Tremor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Urinary retention 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Ventricular tachycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Vertigo 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Vision blurred 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Paroxetine Visual impairment 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine Weight decreased 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine Withdrawal syndrome 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Paroxetine hydrochloride Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine hydrochloride Affect lability 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paroxetine hydrochloride Agitation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine hydrochloride Akathisia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine hydrochloride Amnesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine hydrochloride Anaemia 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Paroxetine hydrochloride Anaphylactic reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine hydrochloride Angioedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine hydrochloride Anxiety 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Paroxetine hydrochloride Aphasia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine hydrochloride Arthralgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine hydrochloride Aspartate aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine hydrochloride Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paroxetine hydrochloride Asthma 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Paroxetine hydrochloride Ataxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine hydrochloride Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paroxetine hydrochloride Blood creatine phosphokinase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine hydrochloride Bradycardia 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Paroxetine hydrochloride Cardiac failure congestive 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Paroxetine hydrochloride Cerebrovascular accident 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Paroxetine hydrochloride Chills 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine hydrochloride Constipation 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Paroxetine hydrochloride Deafness 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Paroxetine hydrochloride Death 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Paroxetine hydrochloride Decreased appetite 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine hydrochloride Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine hydrochloride Delirium 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine hydrochloride Depersonalisation/derealisation disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine hydrochloride Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine hydrochloride Disturbance in attention 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Paroxetine hydrochloride Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Paroxetine hydrochloride Drug dependence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine hydrochloride Dyskinesia 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Paroxetine hydrochloride Dyspnoea 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Paroxetine hydrochloride Dystonia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine hydrochloride Erectile dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paroxetine hydrochloride Eye pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine hydrochloride Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paroxetine hydrochloride Gait disturbance 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Paroxetine hydrochloride Generalised tonic-clonic seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine hydrochloride Haematemesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine hydrochloride Headache 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Paroxetine hydrochloride Hepatic function abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine hydrochloride Hyperbilirubinaemia 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Paroxetine hydrochloride Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine hydrochloride Hypoaesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine hydrochloride Hypocalcaemia 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Paroxetine hydrochloride Hypoglycaemia 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Paroxetine hydrochloride Hypokalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine hydrochloride Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Paroxetine hydrochloride Hypotension 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Paroxetine hydrochloride Inappropriate antidiuretic hormone secretion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Paroxetine hydrochloride Injury 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Paroxetine hydrochloride Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paroxetine hydrochloride Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Paroxetine hydrochloride Libido decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paroxetine hydrochloride Mania 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine hydrochloride Migraine 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine hydrochloride Muscle spasms 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine hydrochloride Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine hydrochloride Mydriasis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine hydrochloride Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine hydrochloride Neck pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paroxetine hydrochloride Otitis media 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Paroxetine hydrochloride Pallor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine hydrochloride Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Paroxetine hydrochloride Paralysis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine hydrochloride Paranoia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine hydrochloride Parosmia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine hydrochloride Photophobia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine hydrochloride Pneumonia 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Paroxetine hydrochloride Pruritus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine hydrochloride Psychotic disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine hydrochloride Pulmonary hypertension 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Paroxetine hydrochloride Pulmonary oedema 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Paroxetine hydrochloride Restless legs syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine hydrochloride Seizure 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Paroxetine hydrochloride Sepsis 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Paroxetine hydrochloride Skin discolouration 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine hydrochloride Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine hydrochloride Tachycardia 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Paroxetine hydrochloride Tinnitus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine hydrochloride Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Paroxetine hydrochloride Urinary retention 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine hydrochloride Urinary tract infection 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Paroxetine hydrochloride Vertigo 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine hydrochloride Vision blurred 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine hydrochloride Visual impairment 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Paroxetine hydrochloride Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Paroxetine hydrochloride Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Paroxetine hydrochloride Withdrawal syndrome 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pasireotide Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pasireotide Alanine aminotransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pasireotide Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pasireotide Back pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pasireotide Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pasireotide Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pasireotide Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pasireotide Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pasireotide Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pasireotide Diarrhoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pasireotide Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pasireotide Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pasireotide Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pasireotide Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pasireotide Hepatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pasireotide Hypercholesterolaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pasireotide Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pasireotide Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pasireotide Hypothyroidism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pasireotide Influenza 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pasireotide Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pasireotide Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pasireotide Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pasireotide Myocardial infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pasireotide Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pasireotide Oedema peripheral 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pasireotide Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pasireotide Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pasireotide Polyuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pasireotide Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pasireotide Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pasireotide Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pasireotide Vision blurred 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pasireotide Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pasireotide diaspartate Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pasireotide diaspartate Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pasireotide diaspartate Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pasireotide diaspartate Hyperglycaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pazopanib Abdominal pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Acute respiratory distress syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Alanine aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Anaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Aphasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Asthenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Asthma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Blood pressure increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Cardiomyopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Deep vein thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Dehydration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Diarrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Disseminated intravascular coagulation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Dysgeusia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Dyspnoea exertional 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Epilepsy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Epistaxis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pazopanib Fatigue 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Febrile neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Gamma-glutamyltransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Haemoptysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Headache 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Hepatic function abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Hepatotoxicity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Hypertension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Hypertensive crisis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Hyperthyroidism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pazopanib Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Hypotension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Hypothyroidism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pazopanib Interstitial lung disease 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Intestinal perforation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Ischaemic stroke 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Jaundice 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Jaundice cholestatic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Liver disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pazopanib Lung infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Lung infiltration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Malaise 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Pazopanib Metastases to central nervous system 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Metastases to liver 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Metastases to lung 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Nausea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Neoplasm 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Paraesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Peritonitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Platelet count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Pleural effusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Pneumonitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Pneumothorax 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Posterior reversible encephalopathy syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Proteinuria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Pulmonary embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Transient ischaemic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Tumour lysis syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib Upper respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Urinary incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib Vomiting 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib White blood cell count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pazopanib hydrochloride Abdominal pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Alanine aminotransferase increased 1.0 1.0 0.0 0.0 1.0 0.0 0.0 Pazopanib hydrochloride Aspartate aminotransferase increased 1.0 1.0 0.0 0.0 1.0 0.0 0.0 Pazopanib hydrochloride Asthenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Blood albumin decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Blood alkaline phosphatase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Blood bilirubin increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Blood glucose increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Cardiac disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Chest pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Chills 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Cough 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Decreased appetite 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Diarrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Dizziness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Dry skin 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Dysgeusia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pazopanib hydrochloride Dysphonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Dyspnoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Electrocardiogram QT prolonged 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Epistaxis 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Pazopanib hydrochloride Fatigue 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Hepatotoxicity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Hypertension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Hypothyroidism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Infection 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Left ventricular dysfunction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Lymphopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Mucosal inflammation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Myalgia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Nausea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Oedema peripheral 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Posterior reversible encephalopathy syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Proteinuria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Stomatitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Vision blurred 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Vomiting 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Pazopanib hydrochloride Weight decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pegfilgrastim Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pegfilgrastim Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pegfilgrastim Bone pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pegfilgrastim Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pegfilgrastim Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pegfilgrastim Hypokalaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pegfilgrastim Leukocytosis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pegfilgrastim Lung infiltration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pegfilgrastim Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pegfilgrastim Nervous system disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pegfilgrastim Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pegfilgrastim Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pegfilgrastim Urticaria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Peginterferon alfa-2b Alopecia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Peginterferon alfa-2b Anaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Peginterferon alfa-2b Anaphylactic reaction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Peginterferon alfa-2b Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Peginterferon alfa-2b Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Peginterferon alfa-2b Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Peginterferon alfa-2b Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Peginterferon alfa-2b Diarrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Peginterferon alfa-2b Dry skin 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Peginterferon alfa-2b Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Peginterferon alfa-2b Haemoglobin decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Peginterferon alfa-2b Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Peginterferon alfa-2b Hypertension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Peginterferon alfa-2b Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Peginterferon alfa-2b Leukopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Peginterferon alfa-2b Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Peginterferon alfa-2b Migraine 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Peginterferon alfa-2b Myalgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Peginterferon alfa-2b Nausea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Peginterferon alfa-2b Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Peginterferon alfa-2b Neutrophil count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Peginterferon alfa-2b Pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Peginterferon alfa-2b Pain in extremity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Peginterferon alfa-2b Platelet count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Peginterferon alfa-2b Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Peginterferon alfa-2b Pyrexia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Peginterferon alfa-2b Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Peginterferon alfa-2b Vomiting 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Peginterferon alfa-2b White blood cell count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pemetrexed Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pemetrexed Acute kidney injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed Acute myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed Anaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Pemetrexed Asthenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed Blood creatinine increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pemetrexed Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pemetrexed Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pemetrexed Dehydration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed Diarrhoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pemetrexed Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pemetrexed Dysphagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed Dyspnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pemetrexed Epistaxis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pemetrexed Erythema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pemetrexed Febrile neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed Interstitial lung disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed Leukopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed Malignant neoplasm progression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed Mucosal inflammation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed Nausea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pemetrexed Nephropathy toxic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pemetrexed Neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed Platelet count decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pemetrexed Pleural effusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed Pneumonitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pemetrexed Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pemetrexed Rash 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pemetrexed Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pemetrexed Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed Toxic epidermal necrolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed Vomiting 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed disodium Abdominal pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed disodium Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pemetrexed disodium Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pemetrexed disodium Constipation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed disodium Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed disodium Dehydration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pemetrexed disodium Diarrhoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Pemetrexed disodium Febrile neutropenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Pemetrexed disodium Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed disodium Interstitial lung disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed disodium Mucosal inflammation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed disodium Neuropathy peripheral 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed disodium Neutropenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed disodium Oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed disodium Pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed disodium Pyrexia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pemetrexed disodium Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pemetrexed disodium Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed disodium Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed disodium Stomatitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pemetrexed disodium Thrombocytopenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Pemetrexed disodium Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Penicillamine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Penicillin g benzathine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Penicillin g benzathine Loss of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Penicillin v Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Penicillin v Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Penicillin v Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Penicillin v Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Penicillin v Rash 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Penicillin v potassium Anaphylactic reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Penicillin v potassium Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Penicillin v potassium Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Penicillin v potassium Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pentostatin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pentostatin Hypotension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pentostatin Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pentostatin Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pentoxifylline Asthenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pentoxifylline Coma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pentoxifylline Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pentoxifylline Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pentoxifylline Jaundice 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pentoxifylline Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pentoxifylline Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pentoxifylline Somnolence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pentoxifylline Subdural haematoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pentoxifylline Tachycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Perampanel Aggression 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Perampanel Anger 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Perampanel Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perampanel Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perampanel Ataxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perampanel Balance disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Perampanel Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perampanel Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perampanel Diplopia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perampanel Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perampanel Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perampanel Gait disturbance 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Perampanel Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perampanel Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perampanel Irritability 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perampanel Mental disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perampanel Mood altered 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perampanel Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perampanel Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perampanel Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perampanel Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perampanel Weight increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perflutren Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Perflutren Back pain 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Perflutren Bradycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Perflutren Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Perflutren Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Perflutren Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Perflutren Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Perflutren Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Perflutren Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Perflutren Erythema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Perflutren Feeling hot 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Perflutren Flushing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Perflutren Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Perflutren Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Perflutren Hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Perflutren Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Perflutren Hypoxia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Perflutren Loss of consciousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Perflutren Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Perflutren Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Perflutren Seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Perflutren Throat tightness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Perflutren Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Perflutren Vomiting 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Perindopril Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perindopril Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perindopril Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Perindopril Asthenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Perindopril Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perindopril Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Perindopril Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perindopril Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perindopril Drug interaction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Perindopril Dyspnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Perindopril Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perindopril Hyperkalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Perindopril Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perindopril Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Perindopril Leukopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perindopril Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perindopril Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perindopril Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perindopril Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perindopril Renal failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perindopril Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perindopril Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perindopril Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perindopril Urticaria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perindopril Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Perindopril erbumine Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Perindopril erbumine Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perindopril erbumine Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Perindopril erbumine Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perindopril erbumine Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perindopril erbumine Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perindopril erbumine Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perindopril erbumine Dysphonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perindopril erbumine Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Perindopril erbumine Hyperkalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perindopril erbumine Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perindopril erbumine Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perindopril erbumine Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perindopril erbumine Renal failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Perindopril erbumine Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Permethrin Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pexidartinib Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pexidartinib Alanine aminotransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pexidartinib Aspartate aminotransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pexidartinib Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pexidartinib Gamma-glutamyltransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pexidartinib Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Phenobarbital Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Phenobarbital Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Phenobarbital Drug reaction with eosinophilia and systemic symptoms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenobarbital Seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Phentermine Acute myocardial infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phentermine Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phentermine Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Phentermine Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phentermine Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Phentermine Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phentermine Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phentermine Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phentermine Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phentermine Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Phentermine Pseudomembranous colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phentermine Subarachnoid haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenylephrine hydrochloride Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Phenytoin Abdominal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Phenytoin Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Alanine aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Phenytoin Altered state of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Amnesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Phenytoin Aphasia 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Phenytoin Aspartate aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Asthenia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Phenytoin Ataxia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Phenytoin Balance disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Phenytoin Blood albumin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Bone marrow failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Phenytoin C-reactive protein increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Phenytoin Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Phenytoin Cerebral infarction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Phenytoin Cerebrovascular accident 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Phenytoin Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Cognitive disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Phenytoin Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Phenytoin Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Phenytoin Confusional state 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Phenytoin Conjunctival hyperaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Coordination abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Phenytoin Crying 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Phenytoin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Phenytoin Deep vein thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Depressed level of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Diarrhoea 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Phenytoin Diplopia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Phenytoin Disease progression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Phenytoin Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Drug abuse 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Phenytoin Drug hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Phenytoin Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Phenytoin Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Drug-induced liver injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Phenytoin Dysarthria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Phenytoin Dyskinesia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Phenytoin Emotional disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Phenytoin Encephalopathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Phenytoin Endocrine disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Eosinophilia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Phenytoin Epilepsy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Phenytoin Epistaxis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Phenytoin Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Phenytoin Gamma-glutamyltransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Phenytoin Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Hemiplegia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Phenytoin Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Phenytoin Hepatic necrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Phenytoin Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Phenytoin Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Phenytoin Ileus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Phenytoin Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Leukocytosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Phenytoin Leukopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Liver injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Phenytoin Lymphadenopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Phenytoin Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Phenytoin Mental disability 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Phenytoin Mental impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Phenytoin Mental status changes 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Phenytoin Metabolic acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Mood swings 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Phenytoin Mouth ulceration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Phenytoin Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Phenytoin Musculoskeletal stiffness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Myocarditis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Phenytoin Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Neoplasm malignant 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Phenytoin Nervousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Phenytoin Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Phenytoin Neurotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Phenytoin Nystagmus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Osteoporosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Phenytoin Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Phenytoin Photophobia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Pleurisy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Pneumonia aspiration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Phenytoin Purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Rash erythematous 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Phenytoin Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Phenytoin Respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Phenytoin Seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Phenytoin Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Phenytoin Septic shock 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Skin exfoliation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Phenytoin Sleep disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Phenytoin Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Speech disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Phenytoin Stevens-Johnson syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Phenytoin Tachycardia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Toxic epidermal necrolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Phenytoin Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Phenytoin Urinary retention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Phenytoin Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin Visual field defect 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Phenytoin Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin sodium Ataxia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Phenytoin sodium Confusional state 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Phenytoin sodium Drug reaction with eosinophilia and systemic symptoms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin sodium Dyskinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin sodium Nystagmus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin sodium Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin sodium Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phenytoin sodium Toxic epidermal necrolysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Phenytoin sodium Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Phytonadione Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pimavanserin Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pimavanserin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pimavanserin tartrate Confusional state 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pimavanserin tartrate Constipation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pimavanserin tartrate Gait disturbance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pimavanserin tartrate Hallucination 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pimavanserin tartrate Nausea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pimavanserin tartrate Oedema peripheral 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pioglitazone Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pioglitazone Anaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pioglitazone Back pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pioglitazone Cardiac failure 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pioglitazone Cardiac failure congestive 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pioglitazone Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pioglitazone Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pioglitazone Diarrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pioglitazone Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pioglitazone Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pioglitazone Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pioglitazone Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pioglitazone Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pioglitazone Interstitial lung disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pioglitazone Liver function test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pioglitazone Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pioglitazone Oedema peripheral 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pioglitazone Pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pioglitazone Pain in extremity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pioglitazone Pancreatic carcinoma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pioglitazone Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pioglitazone Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pioglitazone Prostate cancer 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pioglitazone Pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pioglitazone Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pioglitazone Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pioglitazone Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pioglitazone Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pioglitazone hydrochloride Back pain 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Pioglitazone hydrochloride Cardiac failure 1.0 0.0 0.0 0.0 0.0 1.0 0.0 Pioglitazone hydrochloride Cardiac failure congestive 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Pioglitazone hydrochloride Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pioglitazone hydrochloride Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pioglitazone hydrochloride Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pioglitazone hydrochloride Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pioglitazone hydrochloride Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pioglitazone hydrochloride Urinary tract infection 1.0 0.0 0.0 0.0 0.0 1.0 0.0 Pioglitazone hydrochloride Weight increased 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Piperacillin sodium Haemolytic anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Abasia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Abdominal pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Acute hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Acute myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Acute respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Ageusia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Amnesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Anger 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pirfenidone Anxiety 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Apathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Appetite disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Ascites 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Asthenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Atrial fibrillation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Atrial flutter 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Back pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Blood alkaline phosphatase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pirfenidone Blood bilirubin increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pirfenidone Blood cholesterol increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Blood pressure abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Blood pressure decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Blood urine present 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Breast pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pirfenidone Cachexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Cardiac disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Cardiac failure congestive 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Cardiopulmonary failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Cataract 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Cerebrovascular accident 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Chills 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Cholecystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Chromaturia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Chronic obstructive pulmonary disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Clostridium difficile infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Cold sweat 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Constipation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Contusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Coronary artery disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Cystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Deafness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pirfenidone Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Deep vein thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Dementia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Depressed mood 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Depression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Dermatitis allergic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pirfenidone Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Discomfort 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Dry mouth 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Dry skin 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pirfenidone Dysphagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Dyspnoea exertional 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Eating disorder 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Pirfenidone Eczema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Epigastric discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Erythema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pirfenidone Fatigue 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Feeding disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Feeling cold 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Fluid retention 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Fungal infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Gastritis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Gastrointestinal disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Haemoptysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pirfenidone Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Hepatic cancer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Hepatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Hernia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Hip fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Hyperkalaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Hypersomnia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Hypoacusis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pirfenidone Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Hypotension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Hypoxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Increased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Inflammation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Interstitial lung disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Joint swelling 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Lacrimation increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pirfenidone Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Liver injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pirfenidone Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Lower respiratory tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Lung disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Lung infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Malaise 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Malnutrition 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Memory impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Mental disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Mood altered 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Musculoskeletal pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Musculoskeletal stiffness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Myalgia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Myocardial ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Nasal congestion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Neck pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Neoplasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Nightmare 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pirfenidone Oedema peripheral 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Oropharyngeal pain 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Pirfenidone Osteomyelitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Oxygen saturation decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pirfenidone Palpitations 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Panic attack 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Photosensitivity reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pirfenidone Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Pneumothorax 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Pollakiuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Productive cough 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pirfenidone Pulmonary embolism 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Pulmonary fibrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Pulmonary function test decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Pulmonary hypertension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Pulmonary oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pirfenidone Rash pruritic 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Respiratory disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Respiratory distress 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Retinal detachment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Seizure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Sepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Skin discolouration 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Skin disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pirfenidone Skin exfoliation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pirfenidone Skin irritation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Skin reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pirfenidone Sneezing 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Speech disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Spinal fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Staphylococcal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Stomatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Swelling face 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pirfenidone Throat tightness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Transient ischaemic attack 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone Unevaluable event 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Upper limb fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Upper respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Vasculitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Ventricular tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pirfenidone Weight decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone White blood cell count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pirfenidone White blood cell count increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Piroxicam Acute generalised exanthematous pustulosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Piroxicam Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Piroxicam Drug reaction with eosinophilia and systemic symptoms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Piroxicam Melaena 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Piroxicam Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Piroxicam Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pitavastatin Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pitavastatin calcium Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pitavastatin calcium Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pitavastatin calcium Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pitavastatin calcium Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pitavastatin calcium Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Plecanatide Constipation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Plecanatide Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Plecanatide Diarrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Plerixafor Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Plerixafor Musculoskeletal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Plerixafor Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Plerixafor Paraesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Plerixafor Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Polidocanol Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Polidocanol Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Polidocanol Deep vein thrombosis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Polidocanol Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Polidocanol Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Polidocanol Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Polidocanol Pulmonary embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Polidocanol Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Polyethylene glycol 3350 Abdominal distension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Polyethylene glycol 3350 Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Polyethylene glycol 3350 Dyspnoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Polyethylene glycol 3350 Nausea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Polyethylene glycol 3350 Urticaria 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Polyethylene glycol 3350 Vomiting 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Pomalidomide Abasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Abdominal pain 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Abscess 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Acute hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Acute myeloid leukaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Acute myocardial infarction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Acute respiratory distress syndrome 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Acute respiratory failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Alanine aminotransferase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Altered state of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Anaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Anaphylactic reaction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Angioedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Aphasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Appendicitis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Appetite disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Arthritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Arthropathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Aspartate aminotransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Asthma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Atrial flutter 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Atrioventricular block 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Azotaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Bacteraemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Bacterial infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Balance disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pomalidomide Basal cell carcinoma 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Pomalidomide Blood albumin decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Blood alkaline phosphatase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Blood bilirubin increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Blood count abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Blood creatinine increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Blood glucose decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Blood lactate dehydrogenase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Blood magnesium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Blood potassium increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Blood pressure abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Blood pressure decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Blood pressure fluctuation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Blood urea increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Blood urine present 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Bone disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Bone marrow failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Bradycardia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide C-reactive protein increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Cachexia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Candida infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Cardiac disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Cardiac failure acute 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Cardiac failure congestive 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Cardiogenic shock 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Cardiovascular disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Cerebral infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Cerebrovascular accident 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Cholecystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Chromaturia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Chronic kidney disease 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Pomalidomide Chronic obstructive pulmonary disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Circulatory collapse 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Clostridium difficile infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Colitis ischaemic 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Colon cancer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Coma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Confusional state 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Conjunctivitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Coronary artery disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Cystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Decubitus ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Deep vein thrombosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Delirium 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Dementia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Depressed level of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Discomfort 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Disseminated intravascular coagulation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Disturbance in attention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Diverticulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Drug hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Dry eye 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Dry skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Dysphagia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Eating disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Electrolyte imbalance 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Encephalitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Encephalopathy 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Epistaxis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Erythema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pomalidomide Eye disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Eye haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Failure to thrive 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Febrile neutropenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Feeding disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Feeling hot 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Femur fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Flatulence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Fluid overload 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Fluid retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Full blood count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Furuncle 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Gallbladder disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Gastric disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Gastric haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Gastric ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Gastroenteritis viral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Gastrointestinal haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Gout 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Haemoglobin decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Haemoptysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Haemorrhage intracranial 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Heart rate decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Heart rate irregular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Hemiparesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Hepatic function abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Hepatotoxicity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Herpes zoster 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Hip fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Hyperbilirubinaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Hypercalcaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Hyperglycaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Hyperkalaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Hypoacusis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Hypoglycaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Hypokalaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Hyponatraemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Hypotension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Hypovolaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Hypoxia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Ileus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Ill-defined disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Immune system disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Influenza like illness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Interstitial lung disease 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Intestinal perforation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Lacrimation increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Large intestine perforation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Leukopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Limb discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Liver disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Localised infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Lower respiratory tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Lung disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Lung infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Lung infiltration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Lymphadenopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Lymphocyte count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Lymphopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Malaise 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pomalidomide Meningitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Mental disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Mental status changes 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Metabolic acidosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Migraine 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Movement disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Muscle spasms 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Musculoskeletal pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Musculoskeletal stiffness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Myelodysplastic syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Myocardial infarction 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Myocardial ischaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Neck pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Neutrophil count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Oropharyngeal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Osteomyelitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Osteonecrosis of jaw 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Oxygen saturation decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Paraesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Paralysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Parkinson's disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Pericardial effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Pericarditis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Peripheral sensory neuropathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Plasma cell myeloma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Platelet count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Pleural effusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Pneumocystis jirovecii pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Pneumonia aspiration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Pneumonia bacterial 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Pneumonitis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Pneumothorax 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Productive cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Protein urine present 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Pulmonary alveolar haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Pulmonary embolism 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Pulmonary oedema 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Rash erythematous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Rash pruritic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Renal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Renal failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Renal impairment 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Respiratory disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Respiratory distress 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Respiratory failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Respiratory tract congestion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Respiratory tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Seizure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Sepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Sinusitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Skin cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Skin disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Skin exfoliation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Skin infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Skin lesion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Skin ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Speech disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Spinal compression fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Spinal fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Squamous cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Staphylococcal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Subarachnoid haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Subdural haematoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Swelling face 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Swollen tongue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Tachycardia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Thrombosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Tooth disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Toothache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Transient ischaemic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Treatment failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Troponin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Tumour lysis syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Unevaluable event 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Unresponsive to stimuli 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Upper respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Urosepsis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Vasculitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Visual acuity reduced 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pomalidomide Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pomalidomide White blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pomalidomide White blood cell count increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Abasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Abdominal discomfort 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Acute coronary syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Acute kidney injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Acute myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Acute respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Alanine aminotransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Alopecia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Angina pectoris 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ponatinib Angiopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Ascites 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Aspartate aminotransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Asthenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Atelectasis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Atrial fibrillation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Bacteraemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Blood alkaline phosphatase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Blood bilirubin increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Blood count abnormal 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Blood potassium increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Bone marrow failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Bone pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Cardiac disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Cardiac failure congestive 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Cardiomyopathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ponatinib Cellulitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Cerebral infarction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ponatinib Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Clostridium difficile colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Clostridium difficile infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Colitis ischaemic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Confusional state 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Congestive cardiomyopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Cough 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Decreased appetite 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Deep vein thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Diarrhoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Dry eye 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Dry mouth 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Dry skin 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Dyspepsia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Dysphagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Ejection fraction decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Embolism venous 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Encephalopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Erythema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Face oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Febrile neutropenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Feeling abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Fluid overload 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Fluid retention 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Full blood count decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Fungal infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Gastrointestinal disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Gastrointestinal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Generalised oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Gout 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Haemoglobin decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Hepatic function abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Hepatomegaly 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Hepatotoxicity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Herpes zoster 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Hyperbilirubinaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Hyperkalaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Hypertriglyceridaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ponatinib Hyperuricaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Hypoaesthesia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Hypocalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Hypotension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Hypoxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Jaundice 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Lethargy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Leukocytosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Liver disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Lung disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Malaise 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Malnutrition 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Memory impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Mental status changes 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Migraine 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Mucosal inflammation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Muscle spasms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Myalgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Neuralgia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Neutropenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Neutrophil count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Oedema peripheral 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Pain of skin 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Pancytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Paraesthesia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Pericardial effusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Peripheral ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Platelet count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Pleural effusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Posterior reversible encephalopathy syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ponatinib Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Pulmonary embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Pyrexia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Rash 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Rash erythematous 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Red blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Renal failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Renal impairment 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Skin disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Skin exfoliation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Skin ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Speech disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Staphylococcal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Stomatitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Subdural haematoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Supraventricular tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Tachycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Thrombocytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Treatment failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ponatinib Tumour lysis syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Unevaluable event 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Urinary tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ponatinib Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ponatinib White blood cell count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ponatinib White blood cell count increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Porfimer sodium Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Porfimer sodium Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Posaconazole Acute kidney injury 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Posaconazole Acute myeloid leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Posaconazole Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Posaconazole Atrial fibrillation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Posaconazole Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Posaconazole Cardiac failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Posaconazole Cholestasis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Posaconazole Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Posaconazole Diarrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Posaconazole Drug interaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Posaconazole Drug resistance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Posaconazole Dyspnoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Posaconazole Electrocardiogram QT prolonged 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Posaconazole Fungal infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Posaconazole Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Posaconazole Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Posaconazole Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Posaconazole Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Posaconazole Hypokalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Posaconazole Hypomagnesaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Posaconazole Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Posaconazole Hypotension 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Posaconazole Ileus paralytic 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Posaconazole Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Posaconazole Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Posaconazole Leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Posaconazole Liver function test abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Posaconazole Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Posaconazole Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Posaconazole Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Posaconazole Myelodysplastic syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Posaconazole Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Posaconazole Neutropenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Posaconazole Paraesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Posaconazole Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Posaconazole Pyrexia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Posaconazole Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Posaconazole Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Posaconazole Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Posaconazole Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Posaconazole Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Posaconazole Torsade de pointes 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Posaconazole Toxic skin eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Posaconazole Treatment failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Posaconazole Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Posaconazole Visual impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Potassium chloride Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Potassium chloride Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Potassium chloride Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Potassium chloride Hyperkalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Potassium chloride Vomiting 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pralatrexate Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pralatrexate Blood lactate dehydrogenase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pralatrexate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pralatrexate Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pralatrexate Diarrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pralatrexate Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pralatrexate Febrile neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pralatrexate Lymphopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pralatrexate Malignant neoplasm progression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pralatrexate Mucosal inflammation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pralatrexate Neutropenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pralatrexate Neutrophil count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pralatrexate Platelet count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pralatrexate Pneumocystis jirovecii pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pralatrexate Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pralatrexate Pyrexia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pralatrexate Rash 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pralatrexate Stevens-Johnson syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pralatrexate Stomatitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pralatrexate Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pralatrexate White blood cell count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pramipexole Abasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Agitation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Apathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Balance disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Blood creatine phosphokinase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pramipexole Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Cognitive disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pramipexole Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Crying 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pramipexole Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Depressed level of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pramipexole Depressed mood 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Disorientation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Drug dependence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pramipexole Drug withdrawal syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pramipexole Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Dysphonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Dystonia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Eating disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Emotional disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Extrasystoles 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pramipexole Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pramipexole Fluid retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Gastrooesophageal reflux disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Hallucination 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Hallucination, auditory 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Hiccups 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pramipexole Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Hyperkinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Hypertension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Hyperthermia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Hypoaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Hypokinesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pramipexole Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Inappropriate antidiuretic hormone secretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Irritability 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Joint stiffness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Libido increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Mania 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Movement disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Muscle rigidity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Muscular weakness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pramipexole Musculoskeletal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Musculoskeletal stiffness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Myocardial infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Neuroleptic malignant syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pramipexole Nocturia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Palpitations 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pramipexole Paraesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Parkinson's disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pramipexole Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Personality change 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pramipexole Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pramipexole Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Psychomotor hyperactivity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Psychotic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Pulmonary embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Respiratory distress 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Respiratory failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Restless legs syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Sedation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Shock 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Skin necrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pramipexole Sleep apnoea syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Somnolence 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Speech disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Stress 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pramipexole Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pramipexole Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pramipexole Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Thrombophlebitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Unevaluable event 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole Urinary tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pramipexole Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pramipexole Weight decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole Withdrawal syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole dihydrochloride Altered state of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole dihydrochloride Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole dihydrochloride Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pramipexole dihydrochloride Dementia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pramipexole dihydrochloride Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole dihydrochloride Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole dihydrochloride Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole dihydrochloride Mania 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole dihydrochloride Memory impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pramipexole dihydrochloride Muscle spasms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole dihydrochloride Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole dihydrochloride Oedema peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole dihydrochloride Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole dihydrochloride Pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pramipexole dihydrochloride Parkinson's disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pramipexole dihydrochloride Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pramipexole dihydrochloride Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pramipexole dihydrochloride Psychotic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole dihydrochloride Unevaluable event 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pramipexole dihydrochloride Urinary tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pramipexole dihydrochloride Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prasugrel Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prasugrel Haematochezia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prasugrel Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prasugrel hydrochloride Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Prasugrel hydrochloride Angioedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prasugrel hydrochloride Atrial fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prasugrel hydrochloride Cardiac tamponade 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prasugrel hydrochloride Diarrhoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prasugrel hydrochloride Gastrointestinal haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prasugrel hydrochloride Headache 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prasugrel hydrochloride Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prasugrel hydrochloride Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prasugrel hydrochloride Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prasugrel hydrochloride Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prasugrel hydrochloride Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prasugrel hydrochloride Thrombotic thrombocytopenic purpura 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pravastatin Acute kidney injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pravastatin Alopecia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pravastatin Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pravastatin Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pravastatin Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Pravastatin Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pravastatin Cholestasis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pravastatin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pravastatin Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pravastatin Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pravastatin Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Pravastatin Drug interaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pravastatin Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pravastatin Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pravastatin Epistaxis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pravastatin Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Pravastatin Gastrointestinal disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pravastatin Headache 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pravastatin Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pravastatin Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pravastatin Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pravastatin Interstitial lung disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pravastatin Jaundice 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pravastatin Liver disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pravastatin Liver function test abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pravastatin Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pravastatin Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pravastatin Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pravastatin Musculoskeletal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pravastatin Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pravastatin Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pravastatin Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pravastatin Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pravastatin Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pravastatin Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pravastatin Premature baby 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pravastatin Premature delivery 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pravastatin Pruritus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Pravastatin Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pravastatin Rhabdomyolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pravastatin Tendon rupture 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pravastatin Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pravastatin Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pravastatin sodium Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pravastatin sodium Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pravastatin sodium Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pravastatin sodium Constipation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pravastatin sodium Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pravastatin sodium Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pravastatin sodium Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pravastatin sodium Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pravastatin sodium Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pravastatin sodium Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pravastatin sodium Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pravastatin sodium Myalgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Pravastatin sodium Myopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pravastatin sodium Rhabdomyolysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prazosin Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prazosin Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prazosin Priapism 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Prazosin Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prazosin Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prazosin Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisolone Abdominal distension 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Prednisolone Abscess 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisolone Acne 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisolone Acute coronary syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisolone Affect lability 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisolone Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisolone Arrhythmia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisolone Arthropathy 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Prednisolone Blister 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Prednisolone Bradycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisolone Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisolone Cardiac failure congestive 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisolone Cardiomegaly 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisolone Dermatitis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Prednisolone Dermatitis bullous 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisolone Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisolone Discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisolone Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Prednisolone Dry skin 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Prednisolone Erythema 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Prednisolone Euphoric mood 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisolone Eye irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisolone Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Prednisolone Fluid retention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisolone Glaucoma 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Prednisolone Haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisolone Hepatomegaly 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisolone Herpes simplex 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisolone Hirsutism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisolone Hyperhidrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisolone Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisolone Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisolone Increased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisolone Insomnia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Prednisolone Intracranial pressure increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisolone Intraocular pressure increased 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Prednisolone Loss of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisolone Malaise 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Prednisolone Meningitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisolone Mood swings 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Prednisolone Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisolone Myocardial infarction 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisolone Myopathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisolone Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisolone Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisolone Oedema 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Prednisolone Optic neuritis 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisolone Osteoarthritis 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Prednisolone Osteonecrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisolone Osteoporosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisolone Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisolone Pancreatitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisolone Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisolone Personality change 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisolone Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisolone Rash 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Prednisolone Seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisolone Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisolone Syncope 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisolone Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisolone Tendon rupture 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Prednisolone Urticaria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisolone Vasculitis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Prednisolone Vertigo 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisolone Viral infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisolone Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisolone Visual impairment 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Prednisolone Weight increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Prednisolone acetate Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisolone acetate Eye pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisolone acetate Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisolone acetate Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisolone acetate Intraocular pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisolone acetate Visual acuity reduced 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisolone acetate Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisolone sodium phosphate Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisolone sodium phosphate Osteonecrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Abdominal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Prednisone Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Abdominal pain lower 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Acne 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Acute coronary syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Acute hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Acute myeloid leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Acute myocardial infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Acute pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Acute respiratory distress syndrome 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Acute respiratory failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Aggression 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Prednisone Agitation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Agranulocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Alanine aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Prednisone Altered state of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Anaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Anger 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Anorectal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Anuria 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisone Aphasia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Appendicitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Arrhythmia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Prednisone Arthritis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Prednisone Arthropathy 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Prednisone Aspartate aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Asthenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Asthma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Atelectasis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Atrial fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Bacteraemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Bacterial infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Basal cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisone Blister 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Prednisone Blood bilirubin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Blood pressure increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisone Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Body temperature increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Bone marrow failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Brain oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone C-reactive protein increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Candida infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Cardiac disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisone Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Cardiac failure acute 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Cardiac failure congestive 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Cardiogenic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Cerebral infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Cerebrovascular accident 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Chest discomfort 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Prednisone Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Chills 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Cholangitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Cholecystitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Cholelithiasis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Cholestasis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Chromaturia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Chronic kidney disease 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Circulatory collapse 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Clostridium difficile colitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Clostridium difficile infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Coagulopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Confusional state 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Cough 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Cyanosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Depressed level of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Prednisone Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Diarrhoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisone Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Disease recurrence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Disorientation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Disseminated intravascular coagulation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Disturbance in attention 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Diverticulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Drug dependence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Drug intolerance 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Prednisone Drug reaction with eosinophilia and systemic symptoms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Drug resistance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Drug withdrawal syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Dry eye 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Dry skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Duodenal ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Dysarthria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Dyspepsia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Dysphagia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Dysphonia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisone Dyspnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Eating disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisone Ecchymosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Ejection fraction decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Embolism venous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Emotional distress 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisone Encephalitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Encephalopathy 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Enteritis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Eosinophilia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Epilepsy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Eye disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisone Eye irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Eye pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisone Face oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Prednisone Febrile neutropenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Feeling jittery 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisone Fluid overload 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Foetal death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Foetal growth restriction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Fungal infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Fungal skin infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisone Gastric ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Gastroenteritis viral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisone Gastrointestinal haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Gastrointestinal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Generalised oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Generalised tonic-clonic seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Glossodynia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Prednisone Haematocrit decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Haemodynamic instability 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Haemoptysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Haemorrhage intracranial 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Headache 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Heart rate increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisone Hemiparesis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Hemiplegia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Hepatic encephalopathy 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Hepatic enzyme increased 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Prednisone Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Hepatic necrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Hepatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Hepatitis cholestatic 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Hepatotoxicity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Hernia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Herpes simplex 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Herpes zoster 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Hot flush 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Hyperbilirubinaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Hypercalcaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Hyperglycaemia 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Prednisone Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Prednisone Hyperkalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Hypernatraemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisone Hyperthyroidism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Hypocalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Hypoglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Hypotension 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Hypoxia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Ileus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Ill-defined disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisone Immune thrombocytopenic purpura 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Inflammation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Injury 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisone Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisone Interstitial lung disease 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Irritability 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisone Ischaemic stroke 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Jaundice 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Joint swelling 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Prednisone Lactic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Large intestine perforation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Lethargy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Leukocytosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Leukopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Lip swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Liver injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Loss of consciousness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Prednisone Lower respiratory tract infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisone Lung disorder 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Lung infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Lung infiltration 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Lymphadenopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Lymphopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Malignant melanoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Malnutrition 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Mania 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Melaena 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisone Meningitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Mental status changes 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Metabolic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Middle insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Mobility decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisone Mouth ulceration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Mucosal inflammation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Muscle rigidity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisone Muscle twitching 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Musculoskeletal stiffness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisone Myelodysplastic syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Nasopharyngitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisone Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Necrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Nephropathy toxic 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Nephrotic syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Nervous system disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Neurotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Obstructive airways disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Ocular hyperaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Oedema peripheral 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Oropharyngeal pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Prednisone Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Osteomyelitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Osteonecrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisone Osteoporosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Prednisone Pain in extremity 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Prednisone Pain of skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Pallor 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Palpitations 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisone Pancreatitis acute 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Paraesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Prednisone Pericardial effusion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Pericarditis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisone Peripheral sensory neuropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisone Peritonitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Plasma cell myeloma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Pleural effusion 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Pneumocystis jirovecii pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Pneumonia aspiration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Pneumonitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Pneumothorax 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Polyuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Posterior reversible encephalopathy syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 1.0 Prednisone Premature delivery 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Productive cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Proteinuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Prednisone Psychotic disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisone Pulmonary alveolar haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Pulmonary embolism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Pulmonary fibrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Pulmonary function test decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Pulmonary haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Pulmonary hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Pulmonary mass 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Pulmonary oedema 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Purpura 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Pyelonephritis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Pyrexia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Rash 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Prednisone Rash erythematous 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Rash macular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Rash maculo-papular 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Rash pruritic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Renal impairment 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Renal tubular necrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Respiratory distress 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Retinal detachment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Rheumatoid arthritis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Prednisone Rhinorrhoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Sciatica 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Shock haemorrhagic 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Sinus bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Sinus disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Sinus tachycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Skin cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Skin discolouration 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Skin exfoliation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisone Skin mass 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Skin necrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Skin ulcer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Speech disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Squamous cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Staphylococcal infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Stress 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisone Stress cardiomyopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Suicidal ideation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Prednisone Suicide attempt 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Swelling 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Prednisone Swelling face 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Swollen tongue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Syncope 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Systemic lupus erythematosus 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Prednisone Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Tachypnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Throat irritation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisone Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Thrombosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Tinnitus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Prednisone Torsade de pointes 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Toxic epidermal necrolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Treatment failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisone Tumour lysis syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Unresponsive to stimuli 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Upper gastrointestinal haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Urinary tract infection 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Urosepsis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Urticaria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisone Ventricular fibrillation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Prednisone Viral infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Prednisone Visual acuity reduced 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Prednisone Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Prednisone Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Prednisone Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Prednisone Wheezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prednisone Withdrawal syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Abasia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Abdominal distension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Abdominal pain lower 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Acute hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Acute pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Acute respiratory distress syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Acute respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Aggression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Agitation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Agranulocytosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Akathisia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Alanine aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Altered state of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Amnesia 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Anger 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Angina pectoris 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Anorectal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Apathy 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Aphasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Appetite disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Arthritis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Arthropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Ascites 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Aspartate aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Asphyxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Aspiration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Asthma 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Ataxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Atrial septal defect 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Pregabalin Atrioventricular block complete 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Back pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Bacterial infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Balance disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Blindness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Blister 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Blood alkaline phosphatase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Blood bilirubin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Blood creatine phosphokinase increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Blood creatinine increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Blood pressure abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Blood pressure decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Blood pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Blood triglycerides increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Bradyphrenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Brain injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Brain oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin C-reactive protein increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Candida infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Cardiac disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Cardiomyopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Carpal tunnel syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Cerebral haemorrhage 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Cerebrovascular accident 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Chills 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Choking 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Chromaturia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Chronic obstructive pulmonary disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Coagulopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Cognitive disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Cold sweat 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Coma 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Confusional state 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Pregabalin Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Coordination abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Cyanosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Cyst 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Cystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Decreased appetite 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Pregabalin Decubitus ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Deep vein thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Dementia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Depressed level of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Depressed mood 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Depression 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Diplopia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Disease progression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Disease recurrence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Drug dependence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Drug hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Pregabalin Drug withdrawal syndrome 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Pregabalin Dry eye 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Dry skin 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Dysaesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Dysarthria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Dysmenorrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Dysphagia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Dysphonia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Dyspnoea 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Pregabalin Dysstasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Dystonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Dysuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Ear disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Eating disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Emotional disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Emotional distress 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Encephalopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Epilepsy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Erythema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Euphoric mood 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Extrasystoles 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Eye disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Eye haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Eye irritation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Eye pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Eye pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Eye swelling 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Facial paralysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Feeling hot 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Femur fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Flatulence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Fluid retention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Frequent bowel movements 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Gamma-glutamyltransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Gastrointestinal disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Gastrooesophageal reflux disease 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Generalised tonic-clonic seizure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Haemoglobin decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Haemorrhoids 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Hallucination, visual 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Headache 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Heart rate decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Heart rate increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Heart rate irregular 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Hemiplegia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Hepatic cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Hepatic encephalopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Hepatic failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Hepatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Hepatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Hepatitis cholestatic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Hepatitis fulminant 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Herpes zoster 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Hip fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Hyperaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Hyperbilirubinaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Hypercalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Hypercholesterolaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Hyperglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Hyperhidrosis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Hyperkalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Hyperkinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Hyperreflexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Hypersomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Hyperthermia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Hypoacusis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Hypoaesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Hypoaesthesia oral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Hypoglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Hypokalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Hypothermia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Hypothyroidism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Hypotonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Hypoxia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Ill-defined disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Inappropriate antidiuretic hormone secretion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Incontinence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Increased appetite 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Inflammation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Influenza like illness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Injection site reaction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Injury 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Intentional self-injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Intervertebral disc protrusion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Intestinal obstruction 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Pregabalin Irritability 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Irritable bowel syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Ischaemic stroke 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Jaundice cholestatic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Joint stiffness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Joint swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Laceration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Lactic acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Large intestine perforation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Lethargy 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Leukocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Libido decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Libido increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Limb discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Lip swelling 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Liver disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Liver injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Localised infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Lower respiratory tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Lung disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Lymphadenopathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Lymphoedema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Malaise 0.0 0.0 1.0 0.0 0.0 0.0 1.0 Pregabalin Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Malnutrition 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Mania 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Mental disability 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Mental disorder 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Mental impairment 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Metabolic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Middle insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Migraine 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Miosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Mobility decreased 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Mood altered 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Mood swings 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Motor dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Movement disorder 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Muscle atrophy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Muscle tightness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Muscle twitching 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Musculoskeletal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Musculoskeletal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Musculoskeletal stiffness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Mydriasis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Myoclonus 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Pregabalin Nasopharyngitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Nausea 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Neck pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Nervous system disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Nervousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Neuralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Neuritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Neutrophil count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Night sweats 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Nightmare 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Nocturia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Nuchal rigidity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Nystagmus 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Pregabalin Obesity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Oedema peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Optic neuritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Oral discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Oral disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Oral pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Oropharyngeal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Osteoarthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Osteomyelitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Osteoporosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Oxygen saturation decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Pain of skin 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Pallor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Palpitations 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Pancreatic carcinoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Pancytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Panic attack 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Paraesthesia oral 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Paresis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Parkinson's disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Parkinsonism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Pericardial effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Peripheral coldness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Personality change 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Personality disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Pharyngeal oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Pharyngitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Photophobia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Photosensitivity reaction 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Platelet count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Pleural effusion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Pneumonia aspiration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Pneumonitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Pneumothorax 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Pollakiuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Polyneuropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Polyp 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Poor quality sleep 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Proctalgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Pruritus generalised 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Psychotic disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Pulmonary congestion 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Pulmonary embolism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Pulmonary fibrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Pulmonary hypertension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Rash 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Raynaud's phenomenon 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Red blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Renal failure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Renal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Respiratory depression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Respiratory disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Respiratory distress 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Respiratory failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Restless legs syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Restlessness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Retching 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Retinal detachment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Retinal haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Rheumatoid arthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Rhinorrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Salivary hypersecretion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Sensory disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Sensory loss 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Sepsis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Sexual dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Sinus bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Sinus tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Sinusitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Skin discolouration 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Skin disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Sleep apnoea syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Sleep disorder 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Sluggishness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Somnolence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Sopor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Speech disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Spinal compression fracture 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Spinal fracture 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Staphylococcal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Stress 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Stupor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Suicidal ideation 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Swollen tongue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Systemic lupus erythematosus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Tachypnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Tendon rupture 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Thinking abnormal 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Throat irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Thrombocytopenic purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Tongue oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Toothache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Toxic epidermal necrolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Transaminases increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Treatment failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Tremor 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Unresponsive to stimuli 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Upper gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Upper limb fracture 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Vaginal haemorrhage 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Ventricular fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Visual acuity reduced 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pregabalin Visual field defect 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Vomiting 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Pregabalin Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pregabalin Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Pregabalin Wheezing 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Pregabalin White blood cell count increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Pregabalin Withdrawal syndrome 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Primidone Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Primidone Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Procarbazine hydrochloride Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Procarbazine hydrochloride Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Procarbazine hydrochloride Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Procarbazine hydrochloride Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Procarbazine hydrochloride Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Procarbazine hydrochloride Hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Procarbazine hydrochloride Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Procarbazine hydrochloride Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Procarbazine hydrochloride Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Procarbazine hydrochloride Pancytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Procarbazine hydrochloride Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Procarbazine hydrochloride Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Procarbazine hydrochloride Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Procarbazine hydrochloride Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prochlorperazine Dystonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Prochlorperazine maleate Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Progesterone Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Progesterone Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Progesterone Drug hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Progesterone Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Progesterone Foetal death 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Progesterone Haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Progesterone Pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Progesterone Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Progesterone Pregnancy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Progesterone Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Progesterone Pulmonary embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Progesterone Tinnitus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Progesterone Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Promethazine hydrochloride Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Promethazine hydrochloride Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Promethazine hydrochloride Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Promethazine hydrochloride Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Promethazine hydrochloride Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Promethazine hydrochloride Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Promethazine hydrochloride Dry mouth 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Promethazine hydrochloride Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Promethazine hydrochloride Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Promethazine hydrochloride Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Promethazine hydrochloride Neuroleptic malignant syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Promethazine hydrochloride Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Promethazine hydrochloride Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Promethazine hydrochloride Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Promethazine hydrochloride Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Promethazine hydrochloride Vision blurred 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Promethazine hydrochloride Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Propafenone Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Propafenone Arrhythmia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propafenone Atrial fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propafenone Atrioventricular block first degree 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Propafenone Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propafenone Cardiac arrest 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propafenone Cardiac failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propafenone Cardiogenic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propafenone Cardiotoxicity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propafenone Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propafenone Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Propafenone Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Propafenone Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Propafenone Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propafenone Electrocardiogram abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propafenone Generalised tonic-clonic seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propafenone Hyperkalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Propafenone Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propafenone Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propafenone Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Propafenone Metabolic acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propafenone Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Propafenone Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Propafenone Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propafenone Shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propafenone Sinus bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propafenone Speech disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Propafenone Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propafenone Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Propafenone Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Propafenone Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propafenone Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Propafenone hydrochloride Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Propafenone hydrochloride Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Propafenone hydrochloride Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Proparacaine hydrochloride Conjunctival hyperaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Propofol Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Propofol Acute kidney injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Acute respiratory distress syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Alanine aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Propofol Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Propofol Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Apnoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Propofol Arrhythmia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Aspartate aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Propofol Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Propofol Blood creatine phosphokinase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Propofol Blood pressure decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Blood pressure increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Blood triglycerides increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Propofol Bradycardia 1.0 1.0 0.0 0.0 0.0 1.0 0.0 Propofol Brain injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Propofol Brain oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Propofol Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Cardiac arrest 1.0 1.0 0.0 0.0 0.0 1.0 0.0 Propofol Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Propofol Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Cardiogenic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Circulatory collapse 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Coagulopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Propofol Coma 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Propofol Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Propofol Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Propofol Depressed level of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Propofol Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Propofol Disseminated intravascular coagulation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Propofol Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Propofol Drug withdrawal syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Electrocardiogram abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Propofol Encephalopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Propofol Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Propofol Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Propofol Generalised tonic-clonic seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Propofol Haemodynamic instability 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Headache 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Heart rate decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Propofol Heart rate increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Hepatic enzyme increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Propofol Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Propofol Hepatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Propofol Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Propofol Hyperkalaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Hyperlipidaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Propofol Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Hypertriglyceridaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Hypokalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Hypotension 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Propofol Hypotonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Hypoxia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Lactic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Metabolic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Propofol Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Propofol Myoclonus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Propofol Nausea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Propofol Obstructive airways disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Oliguria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Propofol Oxygen saturation decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Pancreatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Propofol Paraesthesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Pleural effusion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Propofol Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Propofol Pulmonary congestion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Propofol Pulmonary embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Propofol Pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Propofol Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Propofol Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Rash generalised 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Propofol Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Respiratory depression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Respiratory disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Propofol Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Rhabdomyolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Serotonin syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Sinus tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Stress cardiomyopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Propofol Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Propofol Toxic epidermal necrolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Tremor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Unresponsive to stimuli 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Ventricular arrhythmia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Ventricular fibrillation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Ventricular tachycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Propofol Vomiting 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Propofol Wheezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Propranolol hydrochloride Agranulocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Propranolol hydrochloride Amnesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propranolol hydrochloride Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propranolol hydrochloride Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Propranolol hydrochloride Atrioventricular block 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Propranolol hydrochloride Bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Propranolol hydrochloride Constipation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Propranolol hydrochloride Depressed level of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Propranolol hydrochloride Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Propranolol hydrochloride Diarrhoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propranolol hydrochloride Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Propranolol hydrochloride Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Propranolol hydrochloride Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Propranolol hydrochloride Hallucination 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Propranolol hydrochloride Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Propranolol hydrochloride Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Propranolol hydrochloride Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Propranolol hydrochloride Pyrexia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Propranolol hydrochloride Respiratory distress 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propranolol hydrochloride Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Propranolol hydrochloride Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propylthiouracil Acute hepatic failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Propylthiouracil Aplastic anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Propylthiouracil Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Propylthiouracil Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Propylthiouracil Respiratory failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Propylthiouracil Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Propylthiouracil Vasculitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pseudoephedrine hydrochloride Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pseudoephedrine hydrochloride Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pyrazinamide Hepatotoxicity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pyrazinamide Jaundice 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pyridostigmine Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pyrimethamine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Pyrimethamine Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pyrimethamine Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pyrimethamine Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pyrimethamine Neutropenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Pyrimethamine Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Pyrimethamine Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Abdominal distension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Abdominal pain upper 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Abnormal dreams 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Quetiapine Abortion spontaneous 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Quetiapine Acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Acute hepatic failure 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Acute respiratory failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Aggression 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Agitation 0.0 1.0 1.0 0.0 1.0 0.0 0.0 Quetiapine Agranulocytosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Akathisia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Alanine aminotransferase increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Altered state of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Amnesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Anger 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Angina pectoris 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Anxiety 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Quetiapine Apathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Aphasia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Apnoea 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Quetiapine Arrhythmia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Ascites 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Aspartate aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Asphyxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Aspiration 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Asthenia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Quetiapine Asthma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Atrial fibrillation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Atrial septal defect 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Quetiapine Atrioventricular block first degree 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Balance disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Blindness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Quetiapine Blister 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Quetiapine Blood bilirubin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Blood cholesterol increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Blood creatine phosphokinase increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Blood creatinine increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Blood glucose decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Blood potassium increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Blood pressure abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Blood pressure decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Blood pressure fluctuation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Blood sodium decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Blood urea increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Body temperature increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Bone marrow failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Bradyphrenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Brain injury 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Brain oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Bundle branch block 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Candida infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Cardiac disorder 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Cardiogenic shock 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Cardiomegaly 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Cardiomyopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Cardiotoxicity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Cardiovascular disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Catatonia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Cerebral infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Cerebral ischaemia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Cerebrovascular accident 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Chest discomfort 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Chest pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Chills 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Cholestasis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Circulatory collapse 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Cognitive disorder 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Quetiapine Cold sweat 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Colitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Colitis ischaemic 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Coma 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Confusional state 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Congestive cardiomyopathy 1.0 1.0 0.0 1.0 1.0 0.0 0.0 Quetiapine Constipation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Contusion 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Coordination abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Quetiapine Cough 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Quetiapine Crying 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Cyanosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Cystitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Quetiapine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Decreased appetite 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Deep vein thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Delirium 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Dementia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Depersonalisation/derealisation disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Depressed level of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Depressed mood 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Depression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Diabetes mellitus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Diabetic ketoacidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Discomfort 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Disorientation 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Quetiapine Disseminated intravascular coagulation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Disturbance in attention 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Quetiapine Dizziness 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Quetiapine Drug abuse 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Drug dependence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Drug hypersensitivity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Drug interaction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Drug withdrawal syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Drug-induced liver injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Dry mouth 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Dry skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Quetiapine Dry throat 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Dysarthria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Dysgeusia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Dyskinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Dyspepsia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Dysphagia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Dyspnoea 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Quetiapine Dysstasia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Quetiapine Dystonia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Eczema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Quetiapine Electrocardiogram QT prolonged 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Electrocardiogram abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Embolism venous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Quetiapine Emotional disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Encephalopathy 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Epilepsy 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Quetiapine Epistaxis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Extrapyramidal disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Extrasystoles 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Quetiapine Eye disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Eye pain 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Quetiapine Eye swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Quetiapine Face oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Facial paralysis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Quetiapine Faecaloma 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Failure to thrive 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Quetiapine Fatigue 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Quetiapine Fear 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Feeling abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Feeling cold 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Feeling hot 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Feeling jittery 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Quetiapine Femur fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Flushing 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Foetal death 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Quetiapine Foetal growth restriction 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Quetiapine Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Gait disturbance 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Gamma-glutamyltransferase increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Generalised tonic-clonic seizure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Glaucoma 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Gynaecomastia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Haematochezia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Haematocrit decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Haematuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Quetiapine Haemodynamic instability 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Haemoglobin decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Hallucination, visual 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Headache 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Quetiapine Heart rate decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Heart rate increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Heart rate irregular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Quetiapine Hemiparesis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Hemiplegia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Hepatic enzyme increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Hepatic function abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Hepatic steatosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Quetiapine Hepatitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Hepatotoxicity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Hot flush 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Quetiapine Hyperbilirubinaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Hypercholesterolaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Hyperglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Hyperkalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Hyperlipidaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Hypernatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Hyperreflexia 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Quetiapine Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Hypersomnia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Hypertension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Hypertensive crisis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Hyperthermia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Hyperthyroidism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Quetiapine Hypertonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Hypertriglyceridaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Hypoacusis 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Quetiapine Hypoaesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Hypoaesthesia oral 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Hypoglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Hypokinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Hypophagia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Hyporeflexia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Hypothermia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Hypothyroidism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Hypotonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Hypovolaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Hypoxia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Ileus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Ileus paralytic 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Immune system disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Inappropriate antidiuretic hormone secretion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Incontinence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Increased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Infection 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Influenza like illness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Quetiapine Insomnia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Intentional self-injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Intestinal obstruction 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Intracranial pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Ischaemic stroke 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Jaundice 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Joint stiffness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Joint swelling 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Lactic acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Laryngeal oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Lethargy 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Quetiapine Leukocytosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Liver function test abnormal 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Liver injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Loss of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Lung disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Lymphadenopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Malaise 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Mania 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Maternal drugs affecting foetus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Melaena 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Mental disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Mental impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Metabolic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Metabolic disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Quetiapine Miosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Mitral valve incompetence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Mobility decreased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Mood altered 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Mood swings 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Mouth ulceration 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Movement disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Muscle rigidity 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Muscle spasms 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Muscle tightness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Muscle twitching 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Muscular weakness 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Quetiapine Musculoskeletal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Musculoskeletal stiffness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Myalgia 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Mydriasis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Myocardial ischaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Myocarditis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Myoclonus 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Nasal congestion 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Quetiapine Nasopharyngitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Nausea 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Quetiapine Nervous system disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Nervousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Neuroleptic malignant syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Neuropathy peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Night sweats 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Nightmare 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Nuchal rigidity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Nystagmus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Obesity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Obstructive airways disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Ocular hyperaemia 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Quetiapine Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Oedema peripheral 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Oropharyngeal pain 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Oxygen saturation decreased 1.0 1.0 0.0 0.0 1.0 0.0 0.0 Quetiapine Pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Pain in extremity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Pallor 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Quetiapine Pancreatitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Pancreatitis acute 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Pancytopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Panic attack 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Paraesthesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Paraesthesia oral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Quetiapine Paranoia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Parkinsonism 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Pericardial effusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Pericarditis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Peritonitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Personality change 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Pharyngeal oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Pharyngitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Photophobia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Quetiapine Photosensitivity reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Quetiapine Pigmentation disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Platelet count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Pleural effusion 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Pneumonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Pneumonia aspiration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Polyneuropathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Premature baby 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Quetiapine Premature delivery 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Priapism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Productive cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Quetiapine Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Pruritus generalised 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Psychomotor hyperactivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Psychotic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Pulmonary embolism 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Pyrexia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Quetiapine Rash 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Quetiapine Rash erythematous 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Rash generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Renal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Renal impairment 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Respiratory depression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Respiratory disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Respiratory distress 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Respiratory failure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Restless legs syndrome 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Quetiapine Retching 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Sedation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Seizure 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Sensory loss 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Sepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Serotonin syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Sexual dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Quetiapine Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Sinus bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Sinus tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Skin discolouration 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Skin exfoliation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Sleep apnoea syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Sluggishness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Sneezing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Quetiapine Somnolence 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Sopor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Speech disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Staphylococcal infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Status epilepticus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Stevens-Johnson syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Quetiapine Stupor 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Suicide attempt 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Supraventricular tachycardia 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Quetiapine Swelling 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Swelling face 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Swollen tongue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Syncope 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Tachypnoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Tardive dyskinesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Tension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Thinking abnormal 0.0 1.0 1.0 1.0 1.0 0.0 0.0 Quetiapine Thrombocytopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Thrombophlebitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Thrombotic thrombocytopenic purpura 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Tinnitus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Tongue disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Quetiapine Torsade de pointes 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Toxic epidermal necrolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Transaminases increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Transient ischaemic attack 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Quetiapine Tremor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Unresponsive to stimuli 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Upper respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Urinary incontinence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Quetiapine Ventricular arrhythmia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Ventricular fibrillation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Vision blurred 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Visual impairment 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Weight decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine Weight increased 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Quetiapine Wheezing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine White blood cell count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine Withdrawal syndrome 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Quetiapine fumarate Abdominal discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Abdominal distension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Abnormal dreams 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Quetiapine fumarate Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Aggression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Agitation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Akathisia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Alanine aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Amnesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Apathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Aphasia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Arthralgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Arthritis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Aspartate aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Asthma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Atrioventricular block first degree 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Back pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Balance disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Blood cholesterol increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Blood creatinine increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Blood pressure increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Bradycardia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Catatonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Cerebrovascular accident 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Confusional state 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Cyanosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Cystitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Decreased appetite 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Deep vein thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Delirium 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Delusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Depersonalisation/derealisation disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Diabetes mellitus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Dry mouth 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Dysarthria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Dyskinesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Dysphagia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Dyspnoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Dystonia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Ecchymosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Electrocardiogram QT prolonged 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Extrapyramidal disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Eye pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Face oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Gait disturbance 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Galactorrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Quetiapine fumarate Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Gastrooesophageal reflux disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Glaucoma 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Gynaecomastia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Quetiapine fumarate Hallucination 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Heart rate irregular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Quetiapine fumarate Hyperglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Hypersomnia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Hypertension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Hypertonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Hypoaesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Hypoglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Hypothermia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Inappropriate antidiuretic hormone secretion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Intestinal obstruction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Lethargy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Libido decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Quetiapine fumarate Malaise 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Mania 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Muscle spasms 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Muscle twitching 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Musculoskeletal stiffness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Myocarditis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Myoclonus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Nasal congestion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Quetiapine fumarate Nausea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Neck pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Pain in extremity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Palpitations 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Paraesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Paranoia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Pneumonia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Pruritus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Psychotic disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Pyrexia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Restless legs syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Restlessness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Skin discolouration 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Somnolence 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Speech disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Subdural haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Tardive dyskinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Thinking abnormal 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Tinnitus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Tremor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Urinary incontinence 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Urinary retention 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Urinary tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Vision blurred 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Visual impairment 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quetiapine fumarate Weight decreased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quetiapine fumarate Weight increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Quinapril Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Quinapril Blood pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Quinapril Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quinapril Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quinine Acute kidney injury 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Quinine Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Quinine Cardiovascular disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Quinine Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Quinine Coma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Quinine Drug abuse 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Quinine sulfate Thrombocytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rabeprazole Abdominal pain upper 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rabeprazole Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rabeprazole Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rabeprazole Arthralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rabeprazole Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rabeprazole Drug eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rabeprazole Dyspnoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rabeprazole Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rabeprazole Gastrooesophageal reflux disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rabeprazole Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rabeprazole Hypocalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rabeprazole Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rabeprazole Hypomagnesaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rabeprazole Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rabeprazole Melaena 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rabeprazole Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rabeprazole Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rabeprazole Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rabeprazole Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rabeprazole Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rabeprazole Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rabeprazole sodium Agranulocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rabeprazole sodium Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rabeprazole sodium Erythema multiforme 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rabeprazole sodium Hypomagnesaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rabeprazole sodium Stevens-Johnson syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rabeprazole sodium Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rabeprazole sodium Tubulointerstitial nephritis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Raloxifene Pulmonary embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Raloxifene hydrochloride Arthralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Raloxifene hydrochloride Cerebrovascular accident 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Raloxifene hydrochloride Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Raloxifene hydrochloride Embolism venous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Raltegravir potassium Blood bilirubin increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Raltegravir potassium Decreased appetite 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Raltegravir potassium Depression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Raltegravir potassium Diabetes mellitus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Raltegravir potassium Drug eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Raltegravir potassium Erythema 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Raltegravir potassium Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Raltegravir potassium Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Raltegravir potassium Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Raltegravir potassium Hepatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Raltegravir potassium Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Raltegravir potassium Memory impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Raltegravir potassium Musculoskeletal discomfort 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Raltegravir potassium Myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Raltegravir potassium Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Raltegravir potassium Neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Raltegravir potassium Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Raltegravir potassium Neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Raltegravir potassium Pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Raltegravir potassium Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Raltegravir potassium Panic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Raltegravir potassium Somnolence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Raltegravir potassium Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramelteon Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ramelteon Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramelteon Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Abdominal discomfort 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ramipril Abdominal pain lower 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Acute coronary syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Acute generalised exanthematous pustulosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Acute hepatic failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ramipril Acute myocardial infarction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ramipril Acute respiratory distress syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Acute respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ramipril Agitation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Agranulocytosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ramipril Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Ramipril Amnesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Anaphylactoid reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Angina pectoris 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ramipril Angioedema 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ramipril Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Aphasia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Ramipril Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Ramipril Arthropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Aspartate aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Asphyxia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Asthma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Atrial septal defect 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ramipril Atrioventricular block 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Atrioventricular block complete 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Balance disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ramipril Basal cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Blister 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Blood alkaline phosphatase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Blood creatine phosphokinase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ramipril Blood creatinine increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ramipril Blood disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ramipril Blood glucose increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Blood potassium increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Blood pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Blood sodium decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ramipril Blood urea increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Bone marrow failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Bradycardia 0.0 1.0 1.0 0.0 1.0 0.0 0.0 Ramipril Bradyphrenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Bronchitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril C-reactive protein increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Cardiac failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Cardiogenic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Cardiovascular disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Cerebral haemorrhage 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ramipril Cerebrovascular accident 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Chest discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ramipril Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Chills 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Choking 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Cholestasis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Chronic kidney disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Chronic obstructive pulmonary disease 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Circulatory collapse 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ramipril Cognitive disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Cold sweat 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Ramipril Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Confusional state 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ramipril Constipation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Cough 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Ramipril Crying 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Deafness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ramipril Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ramipril Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ramipril Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ramipril Depressed level of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ramipril Depressed mood 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Depression 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Ramipril Dermatitis bullous 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Diabetes mellitus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Diarrhoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ramipril Diplopia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Disease progression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Disorientation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ramipril Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ramipril Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Drug abuse 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Drug dependence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Drug eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Drug hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Drug interaction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ramipril Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ramipril Drug-induced liver injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Ramipril Dysarthria 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ramipril Dyspepsia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Dysphagia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Dyspnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ramipril Dyspnoea exertional 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Ear pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Ejection fraction decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Electrolyte imbalance 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ramipril Enteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Epistaxis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Erectile dysfunction 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Ramipril Erythema 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Ramipril Extrasystoles 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Eye pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Eye swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Eyelid oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Face oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ramipril Feeding disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ramipril Feeling hot 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ramipril Flatulence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Flushing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ramipril Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Gastrointestinal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Gynaecomastia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Haematochezia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Haematoma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Haemoglobin decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Haemolytic anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Hallucination 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ramipril Hallucination, visual 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ramipril Heart rate increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Heart rate irregular 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Hemiparesis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Hemiplegia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Hepatic failure 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Ramipril Hepatic function abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Hepatic necrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Hepatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Hepatomegaly 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ramipril Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ramipril Hyperkalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ramipril Hypersensitivity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ramipril Hypersensitivity vasculitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Hypertensive crisis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Hyperventilation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ramipril Hypoaesthesia oral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Hypoglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ramipril Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ramipril Hypokinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ramipril Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ramipril Hypothermia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Hypoxia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Ill-defined disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Immune thrombocytopenic purpura 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Inappropriate antidiuretic hormone secretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Inflammation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Influenza like illness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ramipril Intentional self-injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Interstitial lung disease 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ramipril Ischaemic stroke 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Ramipril Jaundice 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Ramipril Joint stiffness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Joint swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Lacrimation increased 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Ramipril Lactic acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Laryngeal oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Leukocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Leukopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Libido decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Lip swelling 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Liver function test abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ramipril Liver injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Lower respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Lymphadenopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Melaena 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ramipril Mental impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Metabolic acidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ramipril Miosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Mobility decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ramipril Mouth ulceration 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ramipril Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ramipril Muscle spasms 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Muscle twitching 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Musculoskeletal chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Musculoskeletal stiffness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ramipril Myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Myoclonus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Nasal congestion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Nasopharyngitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Nausea 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Ramipril Neck pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Nervousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Neuralgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ramipril Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Nightmare 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Nocturia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Obstructive airways disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Oliguria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Oral pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ramipril Oropharyngeal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Oxygen saturation decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ramipril Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ramipril Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Ramipril Pain in jaw 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Pallor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Pancytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Ramipril Paranoia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Parosmia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Peripheral ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ramipril Personality change 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ramipril Pharyngeal oedema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ramipril Photosensitivity reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Pneumonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Pneumonia aspiration 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Premature baby 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Ramipril Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Productive cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Psoriasis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ramipril Rash erythematous 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Rash generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Rash macular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Rash papular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Rash pruritic 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ramipril Raynaud's phenomenon 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Rectal haemorrhage 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ramipril Renal failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ramipril Renal impairment 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ramipril Respiratory arrest 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Respiratory distress 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Restlessness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ramipril Retching 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Rhabdomyolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Rhinorrhoea 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Ramipril Seizure 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Ramipril Sepsis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Skin discolouration 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Skin exfoliation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Skin irritation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Sleep disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Sluggishness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Small intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Sopor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Speech disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Squamous cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Stevens-Johnson syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ramipril Stomatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Subarachnoid haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Swelling 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ramipril Swelling face 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Swollen tongue 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ramipril Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Throat tightness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ramipril Tinnitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Tongue oedema 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ramipril Torsade de pointes 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Toxic epidermal necrolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Toxic skin eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ramipril Troponin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Unresponsive to stimuli 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Upper respiratory tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Urinary incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Urinary retention 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Urine output increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Urticaria 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ramipril Vasculitis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ramipril Ventricular extrasystoles 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Ventricular tachycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Viral infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ramipril Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Ramipril Visual impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ramipril Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ramipril Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ramipril Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ramipril White blood cell count increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Abdominal distension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ranitidine Abdominal pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ranitidine Abdominal pain upper 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ranitidine Acute kidney injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Alanine aminotransferase increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ranitidine Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ranitidine Anaphylactic reaction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Anxiety 1.0 0.0 0.0 1.0 0.0 0.0 1.0 Ranitidine Blood creatinine increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ranitidine Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Brain injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Chest discomfort 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ranitidine Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ranitidine Circulatory collapse 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Confusional state 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Constipation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ranitidine Cyanosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ranitidine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Decreased appetite 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ranitidine Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ranitidine Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ranitidine Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ranitidine Drug hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ranitidine Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Ranitidine Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ranitidine Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Electrocardiogram QT prolonged 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ranitidine Emotional distress 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Ranitidine Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Face oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ranitidine Flatulence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ranitidine Foetal growth restriction 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ranitidine Gastrooesophageal reflux disease 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ranitidine Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ranitidine Haemorrhage 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ranitidine Hallucination 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ranitidine Headache 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Heart rate increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ranitidine Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Hypertension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ranitidine Hypokalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Insomnia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ranitidine Irritability 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Leukopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ranitidine Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Mania 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ranitidine Memory impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Nystagmus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ranitidine Ocular hyperaemia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ranitidine Pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ranitidine Palpitations 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Pancreatitis acute 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Paraesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ranitidine Pneumonia 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Ranitidine Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Pruritus generalised 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ranitidine Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ranitidine Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Renal failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Seizure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Toxic epidermal necrolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ranitidine Urinary tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ranitidine Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ranitidine Vision blurred 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ranitidine Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranitidine Wheezing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ranitidine hydrochloride Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ranitidine hydrochloride Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranitidine hydrochloride Angioedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ranitidine hydrochloride Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ranitidine hydrochloride Breast disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ranitidine hydrochloride Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranitidine hydrochloride Confusional state 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ranitidine hydrochloride Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ranitidine hydrochloride Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ranitidine hydrochloride Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ranitidine hydrochloride Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ranitidine hydrochloride Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ranitidine hydrochloride Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ranitidine hydrochloride Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Ranitidine hydrochloride Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ranitidine hydrochloride Malaise 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ranitidine hydrochloride Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ranitidine hydrochloride Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ranitidine hydrochloride Pancreatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ranitidine hydrochloride Pneumonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranitidine hydrochloride Pyrexia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranitidine hydrochloride Tubulointerstitial nephritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ranitidine hydrochloride Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranolazine Abdominal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ranolazine Acute myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ranolazine Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ranolazine Angina pectoris 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ranolazine Angioedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ranolazine Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ranolazine Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ranolazine Blindness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Ranolazine Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ranolazine Blood pressure increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranolazine Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ranolazine Cardiac disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ranolazine Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ranolazine Cardiac failure congestive 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ranolazine Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ranolazine Choking 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ranolazine Circulatory collapse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ranolazine Cognitive disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ranolazine Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ranolazine Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ranolazine Coronary artery disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ranolazine Cough 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ranolazine Deafness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Ranolazine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ranolazine Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ranolazine Dementia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Ranolazine Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ranolazine Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ranolazine Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ranolazine Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ranolazine Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ranolazine Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ranolazine Feeling abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ranolazine Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ranolazine Gastrointestinal disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ranolazine Gastrooesophageal reflux disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ranolazine Generalised tonic-clonic seizure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ranolazine Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ranolazine Hyperkalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ranolazine Hyperlipidaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ranolazine Hypoacusis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Ranolazine Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ranolazine Laceration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ranolazine Lung disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ranolazine Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ranolazine Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ranolazine Mental status changes 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ranolazine Myocardial infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ranolazine Neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ranolazine Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ranolazine Parkinson's disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ranolazine Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ranolazine Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ranolazine Respiratory failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ranolazine Seizure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ranolazine Somnolence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ranolazine Tinnitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ranolazine Transient ischaemic attack 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ranolazine Urinary retention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ranolazine Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ranolazine Urticaria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ranolazine Ventricular fibrillation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ranolazine Ventricular tachycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ranolazine Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ranolazine Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ranolazine Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rasagiline Hypertension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rasagiline mesylate Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rasagiline mesylate Dementia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rasagiline mesylate Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rasagiline mesylate Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rasagiline mesylate Drug interaction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rasagiline mesylate Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rasagiline mesylate Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rasagiline mesylate Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rasagiline mesylate Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rasagiline mesylate Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rasagiline mesylate Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regadenoson Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Regadenoson Atrial fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Regadenoson Atrioventricular block 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Regadenoson Atrioventricular block complete 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Regadenoson Atrioventricular block second degree 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regadenoson Bradycardia 0.0 1.0 0.0 0.0 0.0 1.0 1.0 Regadenoson Cardiac arrest 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Regadenoson Cerebrovascular accident 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Regadenoson Diarrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regadenoson Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regadenoson Dyspnoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regadenoson Flushing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regadenoson Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regadenoson Hyperhidrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regadenoson Hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regadenoson Hypoaesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regadenoson Hypotension 0.0 1.0 0.0 0.0 0.0 1.0 1.0 Regadenoson Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Regadenoson Malaise 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regadenoson Myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Regadenoson Nausea 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Regadenoson Pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regadenoson Pallor 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regadenoson Paraesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regadenoson Respiratory arrest 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Regadenoson Seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regadenoson Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Regadenoson Tachycardia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regadenoson Tremor 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regadenoson Vomiting 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regorafenib Abdominal distension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Abdominal pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Abdominal pain lower 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Acute hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Acute myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Ageusia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regorafenib Alanine aminotransferase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regorafenib Altered state of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Anal incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Anorectal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regorafenib Anuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Arrhythmia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Arthralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regorafenib Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Aspartate aminotransferase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Asthenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Atrial fibrillation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Blister 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regorafenib Blood alkaline phosphatase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Blood bilirubin increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Blood count abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Blood creatine phosphokinase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Blood creatinine increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Blood lactate dehydrogenase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Blood pressure decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Blood sodium decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Burning sensation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Regorafenib C-reactive protein increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Cerebral haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Cerebral infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Cerebrovascular accident 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Cholangitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Cholecystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Chromaturia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Coagulopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Colon cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Coma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Confusional state 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Cystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Deep vein thrombosis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Delirium 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Depressed level of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Dermatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regorafenib Diarrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Disseminated intravascular coagulation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Drug eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Drug hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Drug intolerance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Drug-induced liver injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Dry skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regorafenib Dysgeusia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Dysphagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Dysphonia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regorafenib Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Encephalopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Erythema multiforme 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Faeces discoloured 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Failure to thrive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Fatigue 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Febrile neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Feeding disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Fluid retention 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Gait disturbance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regorafenib Gamma-glutamyltransferase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Gastric haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Gastrointestinal haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Gout 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Haematuria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Haemoglobin decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Hepatic cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Hepatic cirrhosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Hepatic encephalopathy 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Hepatic enzyme increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Hepatic function abnormal 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Hepatitis 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Regorafenib Hepatitis fulminant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Hepatotoxicity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Hydronephrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Hyperbilirubinaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Hypercalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Hyperkalaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Hypertension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Hypoalbuminaemia 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Regorafenib Hypoglycaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Hypophagia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Hypophosphataemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Hypoxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Ileus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Inflammation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Interstitial lung disease 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Intestinal obstruction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Ischaemic stroke 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Jaundice 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Lethargy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Liver disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Liver function test abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Liver function test increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Liver injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Lung disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Lung infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Lymphadenopathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regorafenib Malaise 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Malnutrition 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Melaena 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Metastases to central nervous system 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Metastases to liver 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Metastases to lung 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Mucosal inflammation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Muscle spasms 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regorafenib Musculoskeletal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Musculoskeletal stiffness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Myocardial ischaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Nephrotic syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Neuralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regorafenib Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regorafenib Neutropenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Ocular hyperaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Oedema peripheral 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Pain in extremity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regorafenib Pain of skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regorafenib Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Paraesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regorafenib Peritonitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Platelet count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Pleural effusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Pneumonitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Posterior reversible encephalopathy syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Proteinuria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Pulmonary embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Pyrexia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Rash 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Rash pruritic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regorafenib Renal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Renal impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Renal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regorafenib Respiratory distress 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Seizure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Sepsis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Skin exfoliation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regorafenib Skin lesion 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Regorafenib Sleep disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regorafenib Small intestinal obstruction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Stevens-Johnson syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Thrombocytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Transaminases increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Unevaluable event 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Unresponsive to stimuli 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Upper gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Urticaria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Vaginal haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Regorafenib Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Regorafenib Vomiting 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Regorafenib Weight decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Regorafenib White blood cell count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Regorafenib White blood cell count increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Remifentanil Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Remifentanil Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Repaglinide Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Repaglinide Aphasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Repaglinide Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Repaglinide Blood glucose increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Repaglinide Bradyphrenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Repaglinide Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Repaglinide Diarrhoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Repaglinide Disturbance in attention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Repaglinide Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Repaglinide Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Repaglinide Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Repaglinide Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Repaglinide Hypokinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Repaglinide Lactic acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Repaglinide Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Repaglinide Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Repaglinide Sopor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Repaglinide Urticaria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Repaglinide Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Repaglinide Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Abdominal discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Abdominal pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Acute coronary syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Acute hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Acute kidney injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Acute myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Acute respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Agitation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Agranulocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Alanine aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Alopecia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Amnesia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Anaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Anger 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ribavirin Angioedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Anuria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Aplastic anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Asphyxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Atrial fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Atrial septal defect 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ribavirin Atrioventricular block 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Atrioventricular block complete 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Balance disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ribavirin Blood creatinine increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Blood disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Blood potassium increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Blood pressure decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Blood urea increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Blood uric acid increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Body temperature increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Bone marrow failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Bone pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin C-reactive protein increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Cardiac disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Cardiac failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Cardiovascular disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Cerebral ischaemia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ribavirin Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Chest pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Chills 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Cholangitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Cholecystitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Cholelithiasis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Cholestasis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Chromaturia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Chronic kidney disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Circulatory collapse 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Coagulopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Cognitive disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ribavirin Colitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Colitis ulcerative 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Confusional state 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Constipation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Contusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Cough 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ribavirin Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Decreased appetite 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribavirin Dehydration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Delirium 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Delusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Depressed level of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Depressed mood 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Dermatitis allergic 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Dermatitis exfoliative 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Diabetic ketoacidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Diarrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Diplopia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Disease progression 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Ribavirin Disease recurrence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Disseminated intravascular coagulation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Drug abuse 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Drug dependence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Drug resistance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Drug withdrawal syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Drug-induced liver injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Dry skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Dry throat 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Dysarthria 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Dysgeusia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Dyspepsia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Dysphonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Ear pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Eczema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Electrocardiogram QT prolonged 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Electrolyte imbalance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Encephalopathy 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Epistaxis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Erythema multiforme 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Faeces discoloured 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Fatigue 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Febrile neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Femur fracture 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Gastric ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Gastritis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Gastrointestinal disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Gastrooesophageal reflux disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Generalised oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Gingival bleeding 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Gout 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Haematemesis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Haematochezia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Haematocrit decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Haemolytic anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Haemoptysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Haemorrhage intracranial 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Hallucination 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Hemiparesis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Hepatic cirrhosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Hepatic encephalopathy 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Hepatic function abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Hepatic steatosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Hepatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Hepatitis cholestatic 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Hepatobiliary disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Hepatocellular injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Hyperbilirubinaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Hyperkalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Hyperpyrexia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Hypersensitivity vasculitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Hypertensive crisis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Hypoglycaemia 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Ribavirin Hypokalaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Hyponatraemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Hypothyroidism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Hypoxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Influenza like illness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Ischaemic stroke 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Jaundice 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Ribavirin Laboratory test abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Lactic acidosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Leukopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Liver disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Loss of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Lung disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Lymphocyte count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Lymphoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Lymphopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Malaise 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Malnutrition 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Mania 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Maternal drugs affecting foetus 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ribavirin Melaena 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Mental disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Mobility decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Muscle spasms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ribavirin Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Nausea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Neck pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Neoplasm 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Nephrotic syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Nervousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Night sweats 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Oropharyngeal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Osteomyelitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Pancreatitis acute 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Pancytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Paranoia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Pericardial effusion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Pericarditis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Peritonitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Photosensitivity reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Platelet count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Pleural effusion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Pneumonia bacterial 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Polyuria 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Productive cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Psychotic disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Pulmonary embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Pulmonary fibrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ribavirin Pulmonary oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Rash 0.0 0.0 0.0 0.0 1.0 0.0 1.0 Ribavirin Rash macular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Renal disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Respiratory distress 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Restlessness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Retinal haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Rhabdomyolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Rheumatoid arthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Shock haemorrhagic 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Sinusitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Skin burning sensation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Skin disorder 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Skin irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Sleep disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Somnolence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Splenomegaly 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Stevens-Johnson syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Subarachnoid haemorrhage 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Thrombocytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Toxic skin eruption 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Transaminases increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Treatment failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribavirin Unresponsive to stimuli 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Upper gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Upper respiratory tract infection 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ribavirin Urinary retention 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Urosepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin Vertigo 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Vision blurred 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribavirin Visual acuity reduced 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ribavirin Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Ribavirin Vomiting 1.0 0.0 1.0 0.0 1.0 0.0 0.0 Ribavirin Weight decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribavirin Wheezing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin White blood cell count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribavirin White blood cell count increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribociclib Abdominal discomfort 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Abdominal distension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Abdominal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Abdominal pain upper 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ribociclib Acute respiratory distress syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Agitation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Alanine aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Alopecia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Arthralgia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Ribociclib Ascites 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Aspartate aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Asthenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Atrial fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Back pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Blister 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Blood alkaline phosphatase increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Blood bilirubin increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Blood creatinine increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Blood glucose increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Blood pressure abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribociclib Blood pressure increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Bone marrow failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Bone pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Bradycardia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Breast cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribociclib C-reactive protein increased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ribociclib Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Cardiac disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribociclib Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribociclib Cerebrovascular accident 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribociclib Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Chills 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Chronic obstructive pulmonary disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribociclib Confusional state 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Constipation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Contusion 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Cough 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Decreased appetite 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Deep vein thrombosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ribociclib Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Diarrhoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Discomfort 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribociclib Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Drug hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribociclib Drug intolerance 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Dry skin 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Dysgeusia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Dyspepsia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Dysphagia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Dyspnoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ribociclib Electrocardiogram QT prolonged 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribociclib Electrocardiogram abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Epistaxis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Extrasystoles 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribociclib Eye disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Febrile neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribociclib Feeling abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Feeling hot 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Fluid retention 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Full blood count decreased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Gait disturbance 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Gamma-glutamyltransferase increased 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Gastric disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Gastrointestinal disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Gastrooesophageal reflux disease 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Haematochezia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribociclib Haemoglobin decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Headache 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Hepatic function abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Hepatotoxicity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Hot flush 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Hyperhidrosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Hypertension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Hypoaesthesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Hypokalaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribociclib Hypotension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Hypoxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Ill-defined disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Infection 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ribociclib Influenza 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Insomnia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Interstitial lung disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Jaundice 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Laboratory test abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Liver disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Liver function test increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Loss of consciousness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Lung disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Lymphadenopathy 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Malignant neoplasm progression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Memory impairment 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Metastases to central nervous system 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Metastases to liver 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Metastases to lung 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Muscle spasms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Musculoskeletal chest pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Musculoskeletal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Myalgia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Nasopharyngitis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Neoplasm malignant 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribociclib Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Ribociclib Neutrophil count decreased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Oedema peripheral 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Oral candidiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribociclib Oral pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribociclib Pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Pain in extremity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Palpitations 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Pancreatitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ribociclib Pancytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Paraesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Peripheral swelling 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Platelet count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Pleural effusion 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ribociclib Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ribociclib Pneumonitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Polyneuropathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Ribociclib Pulmonary embolism 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ribociclib Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribociclib Rash 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Ribociclib Rash maculo-papular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ribociclib Rash pruritic 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Red blood cell count decreased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Renal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ribociclib Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Sepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ribociclib Skin discolouration 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Skin exfoliation 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Ribociclib Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Swelling 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Thrombosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Transaminases increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Urinary tract infection 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ribociclib Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Vision blurred 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Visual impairment 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib Vomiting 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ribociclib Weight decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ribociclib Weight increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib White blood cell count decreased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ribociclib White blood cell count increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rifabutin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rifabutin Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifabutin Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifabutin Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifapentine Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifapentine Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Abdominal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Acute kidney injury 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Amnesia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Rifaximin Anaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Ascites 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Bacteraemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rifaximin Blood glucose decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Blood sodium decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Cardiac failure congestive 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rifaximin Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rifaximin Cerebrovascular accident 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Clostridium difficile infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Coma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Deafness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rifaximin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rifaximin Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rifaximin Disease recurrence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Drug hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Dysphagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rifaximin Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Encephalopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Faeces discoloured 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Failure to thrive 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rifaximin Feeling abnormal 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Rifaximin Fluid retention 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Gait disturbance 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Gastrointestinal haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Hepatic cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rifaximin Hepatic cirrhosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rifaximin Hepatic encephalopathy 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rifaximin Hip fracture 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Hyperglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Hyperkalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Hypertension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rifaximin Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Ill-defined disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Liver disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Lung infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Malaise 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Malnutrition 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Memory impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Mental disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rifaximin Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rifaximin Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rifaximin Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Pancytopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rifaximin Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Renal disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rifaximin Renal impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Retching 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Sepsis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rifaximin Shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rifaximin Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Swelling 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Unevaluable event 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rifaximin Unresponsive to stimuli 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rifaximin Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rifaximin Weight decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rifaximin Weight increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rilpivirine hydrochloride Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riluzole Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Riluzole Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Riluzole Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riluzole Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riluzole Multiple organ dysfunction syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Riluzole Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Riluzole Pulmonary embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Riluzole Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Riluzole Sepsis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Riociguat Abdominal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Abdominal pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Riociguat Acute respiratory failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Arrhythmia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Ascites 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Asthenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Asthma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Atrial fibrillation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Atrial flutter 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Balance disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Blood count abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Blood glucose decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Blood potassium increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Blood pressure abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Blood pressure decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Riociguat Cardiac disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Cardiac failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Cardiac failure acute 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Cardiac failure congestive 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Riociguat Cerebrovascular accident 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Chronic kidney disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Riociguat Chronic obstructive pulmonary disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Circulatory collapse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Riociguat Clostridium difficile infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Colon cancer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Confusional state 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Contusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Riociguat Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Riociguat Decreased appetite 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Deep vein thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Depressed mood 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Riociguat Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Drug intolerance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Dyspepsia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Dysphagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Riociguat Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Dyspnoea exertional 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Dysuria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Riociguat Epistaxis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Feeding disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Feeling abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Flank pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Fluid overload 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Fluid retention 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Flushing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Gastric disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Gastroenteritis viral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Gastrointestinal haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Gastrooesophageal reflux disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Generalised oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Gout 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Haematemesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Haematocrit decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Haemoptysis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Heart rate decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Heart rate irregular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Hepatic cirrhosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Riociguat Hip fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Hypoaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Hyponatraemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Riociguat Hypotension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Hypoxia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Ill-defined disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Influenza 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Interstitial lung disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Riociguat Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Joint swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Laboratory test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Laceration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Riociguat Lethargy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Riociguat Limb discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Localised infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Lung disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Riociguat Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Memory impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Migraine 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Riociguat Muscle spasms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Myalgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Riociguat Myocardial ischaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Riociguat Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Nausea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Neck pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Oedema peripheral 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Oesophageal ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Oropharyngeal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Oxygen saturation decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Pain in jaw 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Paraesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Pericardial effusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Peripheral swelling 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Photophobia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Pleural effusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Riociguat Pneumonitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Pneumothorax 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Polyuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Productive cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Pulmonary congestion 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Riociguat Pulmonary embolism 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Pulmonary haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Riociguat Pulmonary hypertension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Pulmonary oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Pyrexia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Rales 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Riociguat Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Renal disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Renal failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Riociguat Respiratory disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Riociguat Respiratory distress 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Respiratory failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Retching 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Seizure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Sepsis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Riociguat Sinusitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Skin ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Small intestinal obstruction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Speech disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Subdural haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Riociguat Swelling 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Systemic lupus erythematosus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Unevaluable event 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Unresponsive to stimuli 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Riociguat Upper gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Vision blurred 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Weight increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Riociguat Wheezing 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Risedronate sodium Abdominal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risedronate sodium Abdominal pain upper 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risedronate sodium Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Risedronate sodium Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risedronate sodium Bone pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risedronate sodium Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risedronate sodium Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risedronate sodium Headache 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Risedronate sodium Musculoskeletal pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Risedronate sodium Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risedronate sodium Nausea 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Risedronate sodium Oesophageal ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risedronate sodium Oesophagitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risedronate sodium Osteonecrosis of jaw 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risedronate sodium Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Abdominal distension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Abdominal pain lower 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Abdominal pain upper 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Abscess 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Acne 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Acute coronary syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Acute generalised exanthematous pustulosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Acute hepatic failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Acute myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Risperidone Acute respiratory distress syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Acute respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Aggression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Agitation 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Risperidone Agranulocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Akathisia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Alanine aminotransferase increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Alopecia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Altered state of consciousness 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Risperidone Amnesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Amylase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Anal incontinence 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Anger 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Angina pectoris 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Angioedema 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Anuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Anxiety 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Risperidone Apathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Aphasia 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Arrhythmia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Arthropathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Ascites 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Aspartate aminotransferase increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Asphyxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Risperidone Aspiration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Asthenia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Risperidone Ataxia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Atrial fibrillation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Atrial septal defect 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Risperidone Atrioventricular block complete 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Atrioventricular block first degree 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Atrioventricular block second degree 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Azotaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Balance disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Blood bilirubin increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Blood cholesterol increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Blood creatine phosphokinase increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Blood creatinine increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Blood glucose increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Blood pressure decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Blood pressure fluctuation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Risperidone Blood pressure increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Blood sodium decreased 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Risperidone Blood triglycerides increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Bone marrow failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Bone pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Bradyphrenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Brain injury 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Brain oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Risperidone Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Breast disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Breast pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Risperidone C-reactive protein increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Cachexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Cardiac disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Cardiac failure 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Cardiovascular disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Catatonia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Cerebral haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Cerebral ischaemia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Cerebrovascular accident 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Chest discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Chest pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Cholecystitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Risperidone Chronic kidney disease 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Chronic obstructive pulmonary disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Circulatory collapse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Risperidone Cognitive disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Colitis ischaemic 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Coma 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Risperidone Confusional state 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Risperidone Cough 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Crying 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Risperidone Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Death 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Deep vein thrombosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Dehydration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Delirium 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Delusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Dementia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Depressed level of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Depressed mood 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Risperidone Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Diabetic ketoacidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Disorientation 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Risperidone Disturbance in attention 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Disturbance in sexual arousal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Drug abuse 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Drug reaction with eosinophilia and systemic symptoms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Dysarthria 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Risperidone Dyskinesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Dysphagia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Dysphoria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Dyspnoea 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Risperidone Dysstasia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Dystonia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Eating disorder 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Risperidone Eczema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Risperidone Ejection fraction decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Electrocardiogram abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Embolism venous 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Risperidone Emotional disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Emotional distress 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Encephalopathy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Epilepsy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Epistaxis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Erectile dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Risperidone Erythema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Erythema multiforme 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Extrapyramidal disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Extrasystoles 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Eye disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Eye pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Eye swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Face oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Risperidone Facial paralysis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Faecaloma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Failure to thrive 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Fear 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Feeding disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Risperidone Feeling abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Femur fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Flatulence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Fluid retention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Gait disturbance 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Galactorrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Gamma-glutamyltransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Gastric cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Risperidone Gastrointestinal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Risperidone Generalised tonic-clonic seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Gynaecomastia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Haematemesis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Haemoglobin decreased 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Risperidone Haemorrhage 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Hallucination 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Risperidone Hallucination, auditory 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Risperidone Hallucination, visual 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Risperidone Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Heart rate decreased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Heart rate irregular 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Hemiparesis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Hepatic encephalopathy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Hepatic failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Hepatic steatosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Hepatitis fulminant 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Hiccups 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Hostility 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Hydronephrosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Hypercholesterolaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Hyperglycaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Hyperhidrosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Hyperkalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Hyperlipidaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Hypernatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Hypersomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Hyperthermia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Risperidone Hypertonia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Hypertriglyceridaemia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Risperidone Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Hypoglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Hypokalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Hypokinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Hypophagia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Hyporeflexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Hypothermia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Hypothyroidism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Hypotonia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Hypoxia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Ileus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Inappropriate antidiuretic hormone secretion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Increased appetite 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Risperidone Inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Influenza like illness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Insomnia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Risperidone Intentional self-injury 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Risperidone Intestinal obstruction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Intracranial pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Irritability 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Risperidone Ischaemic stroke 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Jaundice cholestatic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Joint stiffness 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Lactic acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Laryngospasm 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Risperidone Left ventricular dysfunction 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Lethargy 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Leukocytosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Libido decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Libido increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Lipase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Liver function test abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Risperidone Local swelling 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Risperidone Loss of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Loss of libido 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Lung disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Malaise 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Mania 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Risperidone Memory impairment 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Menorrhagia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Mental disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Mental impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Metabolic acidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Metabolic disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Micturition disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Miosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Mood altered 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Mood swings 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Motor dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Mouth ulceration 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Movement disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Muscle rigidity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Muscle spasms 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Muscle twitching 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Musculoskeletal chest pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Musculoskeletal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Musculoskeletal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Musculoskeletal stiffness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Myalgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Mydriasis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Myocardial infarction 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Myoclonus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Myositis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Neck pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Risperidone Nervous system disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Neuroleptic malignant syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Neuropathy peripheral 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Nightmare 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Nocturia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Nuchal rigidity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Nystagmus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Obesity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Oedema 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Oedema peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Oxygen saturation decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Risperidone Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Pain in extremity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Pallor 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Palpitations 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Pancreatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Pancreatitis acute 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Panic attack 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Paralysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Risperidone Paranoia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Parkinson's disease 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Parkinsonism 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Risperidone Pericardial effusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Peripheral swelling 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Personality change 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Platelet count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Pneumonia aspiration 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Pollakiuria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Risperidone Polyneuropathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Posterior reversible encephalopathy syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Risperidone Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Priapism 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Psychomotor hyperactivity 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Risperidone Psychotic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Pulmonary embolism 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Pyelonephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Pyrexia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Rash 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Rash generalised 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Rash maculo-papular 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Rash pruritic 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Rectal haemorrhage 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Red blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Renal disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Renal impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Respiratory depression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Respiratory distress 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Respiratory failure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Restless legs syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Restlessness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Rhinorrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Risperidone Sedation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Risperidone Serotonin syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Sexual dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Risperidone Shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Sinus bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Sinus tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Skin exfoliation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Sleep apnoea syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Risperidone Sleep disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Sluggishness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Somnolence 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Risperidone Sopor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Speech disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Status epilepticus 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Risperidone Stress 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Stupor 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Sudden death 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Swelling face 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Risperidone Swollen tongue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Tachypnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Tardive dyskinesia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Risperidone Thinking abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Throat tightness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Thrombocytopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Torsade de pointes 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Tremor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Unevaluable event 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Risperidone Unresponsive to stimuli 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Risperidone Urinary retention 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Risperidone Urinary tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Urosepsis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Venous thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Ventricular arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Risperidone Ventricular fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Ventricular tachycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Risperidone Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Visual acuity reduced 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Visual field defect 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Risperidone Weight decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Risperidone Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Risperidone Wheezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone White blood cell count increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Risperidone Withdrawal syndrome 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ritonavir Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ritonavir Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ritonavir Anaemia 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ritonavir Arthralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ritonavir Breast disorder 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ritonavir Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ritonavir Death 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Ritonavir Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ritonavir Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ritonavir Drug interaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ritonavir Drug resistance 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Ritonavir Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ritonavir Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ritonavir Foetal death 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Ritonavir Hepatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ritonavir Hepatocellular injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ritonavir Hepatotoxicity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ritonavir Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ritonavir Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ritonavir Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ritonavir Liver injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ritonavir Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ritonavir Myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ritonavir Myopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ritonavir Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ritonavir Oral candidiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ritonavir Osteonecrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ritonavir Osteoporosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ritonavir Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ritonavir Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ritonavir Premature delivery 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ritonavir Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ritonavir Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ritonavir Sepsis 1.0 1.0 0.0 0.0 1.0 0.0 0.0 Ritonavir Treatment failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ritonavir Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Abasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Abdominal distension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Abdominal pain lower 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Abdominal tenderness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivaroxaban Acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Acute coronary syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Acute generalised exanthematous pustulosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Acute hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Acute myocardial infarction 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Acute pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Acute respiratory failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Agranulocytosis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivaroxaban Altered state of consciousness 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Amnesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Anaemia 1.0 1.0 1.0 0.0 0.0 1.0 0.0 Rivaroxaban Anal incontinence 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Angiopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Aphasia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Rivaroxaban Aplastic anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Appendicitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Arthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivaroxaban Ascites 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Aspiration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Asthenia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Rivaroxaban Ataxia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Atelectasis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Atrial fibrillation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Atrial flutter 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Atrioventricular block 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Atrioventricular block complete 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Azotaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Bacteraemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Balance disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Blindness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Blister 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Blood albumin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Blood count abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Blood glucose increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Blood lactate dehydrogenase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Blood pressure decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Blood pressure increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Blood urea increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Blood urine present 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Bradyphrenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Brain injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Brain oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Cardiac disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Cardiac failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Cardiac failure acute 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Cardiac failure congestive 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Cardiac tamponade 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Cardiogenic shock 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Cardiomegaly 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Cardiomyopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Cardiovascular disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivaroxaban Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Cerebral haemorrhage 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Cerebral infarction 1.0 0.0 1.0 1.0 0.0 0.0 0.0 Rivaroxaban Cerebral ischaemia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Rivaroxaban Cerebrovascular accident 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Cerebrovascular disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Chest discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Chest pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Chills 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Choking 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Cholecystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Cholecystitis acute 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Chromaturia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivaroxaban Chronic kidney disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Chronic obstructive pulmonary disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Circulatory collapse 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Clostridium difficile infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Coagulopathy 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Cognitive disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Cold sweat 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Colitis ischaemic 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Colitis ulcerative 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Coma 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Confusional state 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Rivaroxaban Congestive cardiomyopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Contusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Coronary artery disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Cystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivaroxaban Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Decreased appetite 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Decubitus ulcer 1.0 0.0 1.0 1.0 0.0 0.0 0.0 Rivaroxaban Deep vein thrombosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Delirium 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Dementia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Depressed level of consciousness 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Depressed mood 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Depression 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Rivaroxaban Dermatitis bullous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivaroxaban Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Diarrhoea haemorrhagic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Diplopia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Disease recurrence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivaroxaban Disorientation 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Rivaroxaban Disseminated intravascular coagulation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Disturbance in attention 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Diverticulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Dizziness 0.0 1.0 1.0 1.0 0.0 1.0 0.0 Rivaroxaban Drug eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Drug reaction with eosinophilia and systemic symptoms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Drug-induced liver injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Rivaroxaban Duodenal ulcer 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Dysarthria 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Rivaroxaban Dysphagia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Dysphonia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Dyspnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Dyspnoea exertional 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Dysstasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Eating disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Ecchymosis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Ejection fraction decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Electrocardiogram QT prolonged 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Embolism venous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivaroxaban Encephalopathy 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Epilepsy 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Epistaxis 1.0 0.0 1.0 0.0 0.0 1.0 0.0 Rivaroxaban Erectile dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Erythema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Eye pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Facial paralysis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Faeces discoloured 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Failure to thrive 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Fatigue 0.0 1.0 1.0 1.0 0.0 1.0 0.0 Rivaroxaban Fear 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivaroxaban Febrile neutropenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Feeding disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Feeling cold 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivaroxaban Femur fracture 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Flank pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Fluid overload 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Frequent bowel movements 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Full blood count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Gait disturbance 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Gastric cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Gastric disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Gastric haemorrhage 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Rivaroxaban Gastric ulcer 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Gastritis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Gastrointestinal haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Gastrooesophageal reflux disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Generalised oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Generalised tonic-clonic seizure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Gingival bleeding 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivaroxaban Haematemesis 1.0 1.0 1.0 0.0 0.0 1.0 0.0 Rivaroxaban Haematochezia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Haematocrit decreased 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Rivaroxaban Haematoma 1.0 0.0 1.0 0.0 0.0 1.0 0.0 Rivaroxaban Haematuria 1.0 0.0 1.0 0.0 0.0 1.0 0.0 Rivaroxaban Haemodynamic instability 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Haemoglobin decreased 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Rivaroxaban Haemolytic anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Haemoptysis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Haemorrhage 1.0 0.0 0.0 0.0 0.0 1.0 0.0 Rivaroxaban Haemorrhage intracranial 1.0 1.0 1.0 0.0 0.0 1.0 0.0 Rivaroxaban Haemorrhagic stroke 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Haemorrhoids 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Headache 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Rivaroxaban Heart rate decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Hemiparesis 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Rivaroxaban Hemiplegia 1.0 1.0 1.0 1.0 0.0 0.0 0.0 Rivaroxaban Hepatic cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Hepatic cirrhosis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Hepatic encephalopathy 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Hepatic failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Hepatic function abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Hepatitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Hepatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Hepatitis cholestatic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Hepatocellular injury 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Hip fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Hydronephrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Hyperglycaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Hyperkalaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Hypersensitivity vasculitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Hypertension 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Hypertensive crisis 1.0 1.0 1.0 1.0 0.0 0.0 0.0 Rivaroxaban Hypoacusis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivaroxaban Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Hypoaesthesia oral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivaroxaban Hypoalbuminaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Hypocalcaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Hypoglycaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Hypokalaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Hypokinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Hyponatraemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Hypotension 1.0 1.0 1.0 0.0 0.0 1.0 0.0 Rivaroxaban Hypothermia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Hypovolaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Hypoxia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Ileus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Ileus paralytic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Ill-defined disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Immune thrombocytopenic purpura 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Incontinence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Infarction 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Interstitial lung disease 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Intestinal obstruction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Intestinal perforation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Intracranial pressure increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Iron deficiency anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Ischaemic stroke 1.0 1.0 1.0 1.0 0.0 0.0 0.0 Rivaroxaban Jaundice 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Joint stiffness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivaroxaban Joint swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Laboratory test abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivaroxaban Laceration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Lactic acidosis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Large intestine perforation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Left ventricular dysfunction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Lethargy 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Leukocytosis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Leukopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Limb discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Liver disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Liver function test abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Liver function test increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Liver injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Loss of consciousness 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Lung disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Lung infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Lymphadenopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Lymphoedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivaroxaban Lymphoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Malaise 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Malnutrition 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Melaena 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Rivaroxaban Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Menorrhagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Menstrual disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivaroxaban Mental disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Mental impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Mental status changes 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Metabolic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Metastases to liver 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Metastatic neoplasm 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Metrorrhagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Mobility decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Mood altered 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Motor dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Muscle tightness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivaroxaban Muscular weakness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Musculoskeletal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Musculoskeletal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Musculoskeletal stiffness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Myelodysplastic syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Myocardial infarction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Myocardial ischaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Nasal congestion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Nausea 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Rivaroxaban Neck pain 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Rivaroxaban Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivaroxaban Nephrolithiasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivaroxaban Nervous system disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Neurological symptom 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Obesity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Obstructive airways disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Ocular hyperaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivaroxaban Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Oesophageal ulcer 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Oesophagitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Osteomyelitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Oxygen saturation decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Pain 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Rivaroxaban Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Pain of skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivaroxaban Pallor 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Pancreatic carcinoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Pancytopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Paralysis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Parkinson's disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivaroxaban Peptic ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Pericardial effusion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Pericarditis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Peripheral ischaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Peripheral vascular disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Peritonitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Petechiae 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Pharyngeal oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivaroxaban Photophobia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Plasma cell myeloma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Platelet count decreased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Pleural effusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Pneumonia aspiration 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Pneumonia bacterial 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Pneumonitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Pneumothorax 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Polyneuropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivaroxaban Polyp 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Productive cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Prostate cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Pruritus generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Psychotic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Pulmonary alveolar haemorrhage 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Pulmonary congestion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Pulmonary embolism 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Pulmonary fibrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Pulmonary haemorrhage 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Pulmonary hypertension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Pulmonary mass 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Pulmonary oedema 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Purpura 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Rash erythematous 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Rectal haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Red blood cell count decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Renal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Renal failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivaroxaban Renal tubular necrosis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Respiratory disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Respiratory distress 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Respiratory failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Retinal haemorrhage 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Rhabdomyolysis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Rheumatoid arthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivaroxaban Seizure 1.0 1.0 1.0 1.0 0.0 0.0 0.0 Rivaroxaban Sensory disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Sensory loss 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Sepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Septic shock 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Shock 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Shock haemorrhagic 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Sinus bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Skin infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Skin necrosis 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Rivaroxaban Skin ulcer 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Small intestinal obstruction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Somnolence 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Sopor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Speech disorder 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Rivaroxaban Spinal compression fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Spinal fracture 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivaroxaban Splenomegaly 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Staphylococcal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Status epilepticus 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Subarachnoid haemorrhage 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Subdural haematoma 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Suicide attempt 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Swelling 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Swelling face 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Swollen tongue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Syncope 1.0 1.0 1.0 0.0 0.0 1.0 0.0 Rivaroxaban Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Tachypnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Thirst 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivaroxaban Thrombocytopenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Thrombosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivaroxaban Thrombotic thrombocytopenic purpura 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Tooth abscess 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivaroxaban Transient ischaemic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Treatment failure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Troponin increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Unresponsive to stimuli 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Upper gastrointestinal haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Upper respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Urinary incontinence 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Urinary tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Urosepsis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Vaginal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Vascular purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Venous thrombosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Ventricular fibrillation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban Ventricular tachycardia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Vertigo 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Visual acuity reduced 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivaroxaban Vomiting 1.0 1.0 1.0 0.0 0.0 1.0 0.0 Rivaroxaban Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivaroxaban Wheezing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban White blood cell count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivaroxaban White blood cell count increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine Abdominal distension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine Abdominal pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine Abdominal pain upper 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine Acute kidney injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivastigmine Asthenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivastigmine Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine Cognitive disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivastigmine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine Decreased appetite 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivastigmine Dementia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivastigmine Depression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine Dermatitis allergic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivastigmine Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivastigmine Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine Drug intolerance 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine Dyskinesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivastigmine Feeling abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivastigmine Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivastigmine Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine Haematemesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivastigmine Hallucination 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivastigmine Hallucination, visual 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivastigmine Hip fracture 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine Hypophagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine Insomnia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine Malaise 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine Memory impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivastigmine Mental impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivastigmine Miosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivastigmine Mobility decreased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Rivastigmine Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine Musculoskeletal stiffness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivastigmine Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine Parkinson's disease 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivastigmine Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivastigmine Pyrexia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivastigmine Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine Sinus bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivastigmine Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivastigmine Urinary tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivastigmine Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivastigmine Weight decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine tartrate Aggression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine tartrate Agitation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivastigmine tartrate Amnesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivastigmine tartrate Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivastigmine tartrate Aphasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rivastigmine tartrate Asthenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine tartrate Balance disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivastigmine tartrate Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivastigmine tartrate Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine tartrate Cardiac disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine tartrate Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine tartrate Cerebrovascular accident 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine tartrate Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine tartrate Cough 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine tartrate Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivastigmine tartrate Delirium 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivastigmine tartrate Dementia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Rivastigmine tartrate Depression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine tartrate Diabetes mellitus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine tartrate Dysphagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine tartrate Dyspnoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine tartrate Feeling abnormal 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Rivastigmine tartrate Gait disturbance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivastigmine tartrate Gastrointestinal disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine tartrate Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivastigmine tartrate Hypersensitivity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine tartrate Hypertension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine tartrate Loss of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine tartrate Malaise 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine tartrate Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine tartrate Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine tartrate Nervousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivastigmine tartrate Pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine tartrate Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine tartrate Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rivastigmine tartrate Pyrexia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine tartrate Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine tartrate Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine tartrate Seizure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine tartrate Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine tartrate Tremor 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rivastigmine tartrate Urinary tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rivastigmine tartrate Weight decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rizatriptan Aggression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rizatriptan Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rizatriptan Asthenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rizatriptan Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rizatriptan Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rizatriptan Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rizatriptan Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rizatriptan Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rizatriptan Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rizatriptan benzoate Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rizatriptan benzoate Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rizatriptan benzoate Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rizatriptan benzoate Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rizatriptan benzoate Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rizatriptan benzoate Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rizatriptan benzoate Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rocuronium bromide Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Rocuronium bromide Arrhythmia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rocuronium bromide Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rocuronium bromide Hypotension 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Rocuronium bromide Paralysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rocuronium bromide Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rocuronium bromide Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rofecoxib Cerebrovascular accident 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Roflumilast Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Roflumilast Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Roflumilast Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Roflumilast Chronic obstructive pulmonary disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Roflumilast Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Roflumilast Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Roflumilast Decreased appetite 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Roflumilast Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Roflumilast Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Roflumilast Diarrhoea 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Roflumilast Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Roflumilast Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Roflumilast Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Roflumilast Oxygen saturation decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Roflumilast Pneumonia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Roflumilast Pulmonary mass 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Roflumilast Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Roflumilast Suicidal ideation 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Roflumilast Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Roflumilast Weight decreased 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Rolapitant Abdominal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rolapitant Urinary tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Romidepsin Acute kidney injury 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Romidepsin Amenorrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Romidepsin Anaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Romidepsin Asthenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Romidepsin Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Romidepsin Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Romidepsin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Romidepsin Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Romidepsin Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Romidepsin Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Romidepsin Febrile neutropenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Romidepsin Hypotension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Romidepsin Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Romidepsin Myelodysplastic syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Romidepsin Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Romidepsin Neutropenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Romidepsin Platelet count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Romidepsin Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Romidepsin Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Romidepsin Pyrexia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Romidepsin Sepsis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Romidepsin Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Romidepsin Stomatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Romidepsin Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Romidepsin Tumour lysis syndrome 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Romidepsin Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Abnormal faeces 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Agitation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ropinirole Anal incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Aphasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Cognitive disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ropinirole Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Delusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Depressed level of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Depressed mood 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Diarrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ropinirole Disturbance in attention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Emotional disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Feeling abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Hyperkinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Increased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Memory impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Mental disorder 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Ropinirole Muscle rigidity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ropinirole Nocturia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Personality disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Pollakiuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Poor quality sleep 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Restless legs syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ropinirole Restlessness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Sleep disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Tension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Unevaluable event 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Urinary incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole Withdrawal syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ropinirole hydrochloride Anxiety 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ropinirole hydrochloride Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole hydrochloride Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole hydrochloride Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole hydrochloride Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropinirole hydrochloride Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ropinirole hydrochloride Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ropinirole hydrochloride Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropivacaine Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ropivacaine Cardiac arrest 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ropivacaine Hypotension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ropivacaine hydrochloride Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ropivacaine hydrochloride Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ropivacaine hydrochloride Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ropivacaine hydrochloride Dyspnoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ropivacaine hydrochloride Generalised tonic-clonic seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropivacaine hydrochloride Hypoaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropivacaine hydrochloride Hypotension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ropivacaine hydrochloride Tachycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ropivacaine hydrochloride Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ropivacaine hydrochloride Ventricular fibrillation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosiglitazone Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosiglitazone Coronary artery disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosiglitazone maleate Acute coronary syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosiglitazone maleate Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosiglitazone maleate Cardiac disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosiglitazone maleate Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rosiglitazone maleate Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 1.0 Rosiglitazone maleate Cerebrovascular accident 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosiglitazone maleate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rosiglitazone maleate Diabetes mellitus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rosiglitazone maleate Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosiglitazone maleate Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosiglitazone maleate Fluid retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosiglitazone maleate Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rosiglitazone maleate Hyperlipidaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosiglitazone maleate Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosiglitazone maleate Injury 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosiglitazone maleate Ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosiglitazone maleate Myocardial infarction 1.0 0.0 1.0 0.0 0.0 0.0 1.0 Rosiglitazone maleate Myocardial ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosiglitazone maleate Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosiglitazone maleate Pleural effusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosiglitazone maleate Pulmonary oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosiglitazone maleate Weight increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosuvastatin Abdominal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Rosuvastatin Abdominal distension 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Rosuvastatin Abdominal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Abdominal pain upper 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Acute hepatic failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosuvastatin Acute kidney injury 0.0 1.0 1.0 0.0 1.0 1.0 0.0 Rosuvastatin Acute myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Aggression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Agranulocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosuvastatin Alanine aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Amnesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Amylase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Anaphylactic shock 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosuvastatin Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Rosuvastatin Arthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Arthropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Aspartate aminotransferase increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Asthma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Atrial fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Back pain 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Rosuvastatin Balance disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosuvastatin Blood cholesterol increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Blood creatine phosphokinase increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Blood creatinine increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Blood pressure decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Blood pressure fluctuation 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Rosuvastatin Blood pressure increased 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Rosuvastatin Blood triglycerides increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Blood urea increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Blood urine present 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Bone pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rosuvastatin Breast pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosuvastatin Burning sensation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Cardiac disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Cardiac failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosuvastatin Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosuvastatin Cardio-respiratory arrest 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Cerebral haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Cerebral infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Choking 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosuvastatin Chromaturia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Chronic kidney disease 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Chronic obstructive pulmonary disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Confusional state 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Constipation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Contusion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Coronary artery disease 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Cough 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Rosuvastatin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rosuvastatin Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosuvastatin Depressed mood 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Dermatitis bullous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Diabetic ketoacidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Disseminated intravascular coagulation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Disturbance in attention 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Rosuvastatin Drug eruption 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Drug hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Drug interaction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rosuvastatin Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Drug-induced liver injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosuvastatin Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Dysarthria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Dyskinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Dysphagia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Dysphonia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Dyspnoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Dysstasia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Eczema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosuvastatin Electrocardiogram abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosuvastatin Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosuvastatin Epistaxis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Erythema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Extrasystoles 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Feeling abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Flatulence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Fungal infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Gait disturbance 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Gamma-glutamyltransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosuvastatin Haemoptysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Hepatic enzyme increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Hepatic function abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Hepatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosuvastatin Hepatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosuvastatin Hepatocellular injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Hot flush 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Hyperaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Hyperglycaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Hyperkalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Hypersensitivity 0.0 0.0 0.0 0.0 1.0 0.0 1.0 Rosuvastatin Hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Hypoglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Hypokinesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosuvastatin Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rosuvastatin Hypotonia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Intervertebral disc protrusion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Irritability 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Ischaemic stroke 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosuvastatin Jaundice 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Joint swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Laboratory test abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Lactic acidosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Leukocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Limb discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Lip swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Lipase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Liver function test abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Lung disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Malaise 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Rosuvastatin Memory impairment 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Metabolic acidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rosuvastatin Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Movement disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Muscle contractions involuntary 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Muscle tightness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Muscle twitching 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Muscular weakness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Musculoskeletal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Musculoskeletal stiffness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Myalgia 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Rosuvastatin Myopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Myositis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Nasopharyngitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Nausea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Neck pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Oedema peripheral 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Oliguria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Oropharyngeal pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Rosuvastatin Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosuvastatin Osteoarthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Rosuvastatin Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Rosuvastatin Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosuvastatin Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Photophobia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Pneumonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Pollakiuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Polyneuropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Priapism 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Productive cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Rosuvastatin Psoriasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Rales 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosuvastatin Rash 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Rosuvastatin Renal failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Renal tubular necrosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rosuvastatin Respiratory disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Respiratory distress 1.0 1.0 0.0 0.0 1.0 0.0 0.0 Rosuvastatin Respiratory failure 1.0 1.0 0.0 0.0 1.0 0.0 0.0 Rosuvastatin Restless legs syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Rosuvastatin Rheumatoid arthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Sedation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosuvastatin Sinusitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Sleep disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Somnolence 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Speech disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Suicidal ideation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Supraventricular extrasystoles 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Swelling 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Rosuvastatin Swelling face 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Rosuvastatin Swollen tongue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Tendon rupture 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Tendonitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Throat irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Tinnitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Transaminases increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rosuvastatin Transient ischaemic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosuvastatin Tremor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Upper gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosuvastatin Urinary tract infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin Ventricular fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Vomiting 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin calcium Abdominal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin calcium Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rosuvastatin calcium Amnesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin calcium Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Rosuvastatin calcium Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin calcium Blood creatine phosphokinase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin calcium Confusional state 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin calcium Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin calcium Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin calcium Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin calcium Diabetes mellitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin calcium Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin calcium Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin calcium Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin calcium Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin calcium Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosuvastatin calcium Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin calcium Myopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rosuvastatin calcium Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin calcium Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin calcium Nightmare 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rosuvastatin calcium Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rosuvastatin calcium Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Rosuvastatin calcium Rash 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rosuvastatin calcium Rhabdomyolysis 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Rosuvastatin calcium Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rotigotine Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rotigotine Ageusia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rotigotine Anal incontinence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rotigotine Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rotigotine Aphasia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rotigotine Asthenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rotigotine Balance disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rotigotine Blister 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rotigotine Cardiac disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rotigotine Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rotigotine Cardiac failure congestive 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rotigotine Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rotigotine Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rotigotine Choking 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rotigotine Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rotigotine Constipation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rotigotine Contusion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rotigotine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rotigotine Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rotigotine Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rotigotine Delusion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rotigotine Depressed mood 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rotigotine Diarrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rotigotine Disturbance in attention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rotigotine Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rotigotine Dysphagia 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Rotigotine Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rotigotine Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rotigotine Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rotigotine Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rotigotine Hallucination, auditory 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rotigotine Hip fracture 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rotigotine Infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rotigotine Inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rotigotine Intestinal obstruction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rotigotine Libido decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rotigotine Limb discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rotigotine Memory impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rotigotine Micturition urgency 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rotigotine Middle insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rotigotine Motor dysfunction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rotigotine Musculoskeletal stiffness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rotigotine Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rotigotine Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rotigotine Nightmare 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rotigotine Nocturia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rotigotine Pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rotigotine Panic attack 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rotigotine Parkinson's disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rotigotine Pleural effusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rotigotine Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rotigotine Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rotigotine Poor quality sleep 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rotigotine Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rotigotine Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rotigotine Respiratory disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rotigotine Restless legs syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Rotigotine Restlessness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rotigotine Sensory disturbance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rotigotine Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rotigotine Sexual dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rotigotine Skin irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rotigotine Sleep disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rotigotine Stress 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rotigotine Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rotigotine Tremor 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Rotigotine Urinary tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Rotigotine Weight decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rucaparib Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rucaparib Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Rucaparib Bone marrow failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rucaparib Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rucaparib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rucaparib Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rucaparib Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rucaparib Febrile neutropenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Rucaparib Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rucaparib Pancytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rucaparib Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rucaparib Thrombocytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Rucaparib Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rufinamide Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rufinamide Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rufinamide Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rufinamide Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rufinamide Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Rufinamide Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Abdominal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Acne 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Acute myeloid leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Acute myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Acute respiratory distress syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Acute respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Agitation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Alanine aminotransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Amnesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Arthralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Arthritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Aspartate aminotransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Atrial fibrillation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Bacteraemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Bacterial infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Balance disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Basal cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Blindness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Blister 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Blood alkaline phosphatase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Blood bilirubin increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Blood cholesterol increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Blood count abnormal 0.0 0.0 1.0 0.0 0.0 0.0 1.0 Ruxolitinib Blood creatinine increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Blood glucose decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Blood glucose increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Blood lactate dehydrogenase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Blood potassium increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Blood pressure abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Blood pressure decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Blood pressure increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Blood sodium decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Blood triglycerides increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Blood urea increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Blood urine present 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Bone marrow failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Bone pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Burning sensation 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Bursitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib C-reactive protein increased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Cachexia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Candida infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Cardiac disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Cardiac failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Cardiac failure congestive 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Cardiovascular disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Cellulitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Cerebral haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Chest pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Chromaturia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Chronic kidney disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Chronic obstructive pulmonary disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Circulatory collapse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Clostridium difficile infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Coagulopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Colon cancer 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Contusion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Coronary artery disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Cystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Decreased appetite 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Deep vein thrombosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Dehydration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Delirium 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Depressed mood 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Dermatitis bullous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Disseminated intravascular coagulation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Diverticulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Dizziness postural 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Drug resistance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Drug withdrawal syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Dry eye 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Dry skin 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Dysgeusia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Dysphagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Dysuria 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Encephalitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Encephalopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Eructation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ruxolitinib Eye haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Eye pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ruxolitinib Faeces discoloured 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Febrile neutropenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Feeding disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Feeling abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Feeling hot 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Femur fracture 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Flank pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Flatulence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Fluid retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Full blood count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Fungal infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Furuncle 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Gamma-glutamyltransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Gastric ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Gastrooesophageal reflux disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Generalised oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Gout 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Haematemesis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Haematoma 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Haematuria 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Haemoglobin decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Haemolysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Haemoptysis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Haemorrhage intracranial 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Haemorrhoids 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Hallucination 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Hepatic cirrhosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Hepatic function abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Hepatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Herpes simplex 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Herpes zoster 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Hip fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Hypercalcaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Hyperkalaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Hypoaesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Hypocalcaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Hypoglycaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Hypokalaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Hypotension 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Hypoxia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Increased appetite 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Inflammation 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Influenza 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Interstitial lung disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Intestinal perforation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Jaundice 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Laceration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Lacrimation increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Large intestine perforation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Leukocytosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Leukopenia 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Liver disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Liver function test abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Liver function test increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Lung disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Lung infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Lung infiltration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Lung neoplasm malignant 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Ruxolitinib Lymphadenopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Lymphocyte count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Malignant melanoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Malnutrition 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Ruxolitinib Melaena 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Memory impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Mental impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Mental status changes 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Metastases to liver 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Mobility decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Mood swings 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Mucosal inflammation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Musculoskeletal chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Myelodysplastic syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Nasal congestion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Nasopharyngitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Neuralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Neutrophil count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Night sweats 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Nocturia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Oedema peripheral 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Oral pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Oropharyngeal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Oxygen saturation decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Pallor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Palpitations 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Pancreatic carcinoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Pancreatitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Pancytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Paraesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Pericarditis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Peripheral ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Photosensitivity reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Pigmentation disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Plasma cell myeloma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Platelet count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Pleural effusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Pneumonitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Pruritus generalised 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Pulmonary alveolar haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Pulmonary congestion 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Pulmonary embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Pulmonary haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Pulmonary hypertension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Pulmonary mass 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Pulmonary oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Pyrexia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Red blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Renal disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Renal impairment 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Respiratory disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Respiratory distress 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Respiratory tract congestion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Rhinorrhoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Scab 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Sepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Sinusitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Skin burning sensation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Skin cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Skin disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Skin exfoliation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Splenomegaly 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Squamous cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Staphylococcal infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Stress 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Subarachnoid haemorrhage 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Ruxolitinib Subdural haematoma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Swollen tongue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Throat tightness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Thrombocytosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Tooth abscess 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Treatment failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Tumour lysis syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Unresponsive to stimuli 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Upper gastrointestinal haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Upper limb fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Urosepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Vertigo 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Visual acuity reduced 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Weight decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ruxolitinib Weight increased 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Ruxolitinib White blood cell count increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ruxolitinib Withdrawal syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Salicylic acid Burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Salicylic acid Pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Salicylic acid Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Salicylic acid Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sapropterin dihydrochloride Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sapropterin dihydrochloride Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sapropterin dihydrochloride Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sapropterin dihydrochloride Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sapropterin dihydrochloride Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Saxagliptin Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Saxagliptin Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Saxagliptin Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Saxagliptin Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Saxagliptin Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Saxagliptin hydrochloride Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Saxagliptin hydrochloride Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Scopolamine Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Scopolamine Balance disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Scopolamine Confusional state 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Scopolamine Disorientation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Scopolamine Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Scopolamine Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Scopolamine Dysuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Scopolamine Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Scopolamine Hallucination 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Scopolamine Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Scopolamine Mydriasis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Scopolamine Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Scopolamine Speech disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Scopolamine Vertigo 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Scopolamine Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Scopolamine Vomiting 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Scopolamine Withdrawal syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Selegiline Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Abdominal discomfort 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Abdominal distension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Abdominal pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Abdominal pain upper 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Acute kidney injury 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Acute respiratory failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Selexipag Alopecia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Selexipag Anaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Anal incontinence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Selexipag Anxiety 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Arthralgia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Arthritis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Selexipag Ascites 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Asthenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Asthma 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Selexipag Atrial fibrillation 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Selexipag Back pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Blood bilirubin increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Blood glucose decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Blood potassium decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Blood potassium increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Blood pressure abnormal 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Blood pressure decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Blood pressure fluctuation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Bone pain 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Selexipag Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Burning sensation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Cardiac arrest 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Cardiac disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Cardiac failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Selexipag Cardiac failure acute 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Selexipag Cardiac failure congestive 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Cerebrovascular accident 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Cholecystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Chronic obstructive pulmonary disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Clostridium difficile infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Confusional state 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Constipation 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Selexipag Contusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Cyanosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Cystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Selexipag Decreased appetite 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Dehydration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Depressed mood 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Depression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Diarrhoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Disease progression 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Disorientation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Dizziness 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Drug intolerance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Dry mouth 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Dysgeusia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Dyspepsia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Dysphagia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Dysphonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Dyspnoea exertional 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Ear pain 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Selexipag Epistaxis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Selexipag Erythema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Eye pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Eye swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Facial paralysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Faeces discoloured 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Fatigue 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Feeding disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Feeling abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Feeling jittery 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Femur fracture 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Selexipag Flatulence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Fluid overload 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Fluid retention 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Flushing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Frequent bowel movements 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Gastric haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Gastroenteritis viral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Gastrointestinal haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Gastrooesophageal reflux disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Generalised oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Gingival bleeding 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Haematochezia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Haematocrit decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Selexipag Haemoglobin decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Haemoptysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Headache 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Heart rate decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Heart rate irregular 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Hepatic cirrhosis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Hepatic encephalopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Herpes zoster 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Hip fracture 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Hot flush 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Hypersomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Selexipag Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Hyperthyroidism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Selexipag Hypoacusis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Hypoaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Hypokalaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Hypokinesia 1.0 0.0 1.0 1.0 0.0 0.0 0.0 Selexipag Hypotension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Hypoxia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Selexipag Infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Influenza like illness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Insomnia 1.0 0.0 1.0 1.0 0.0 0.0 0.0 Selexipag Interstitial lung disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Joint stiffness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Joint swelling 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Lethargy 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Limb discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Liver disorder 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Selexipag Liver function test increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Localised infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Loss of consciousness 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Lung disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Lung infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Selexipag Lymphoedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Selexipag Lymphoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Selexipag Malaise 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Memory impairment 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Selexipag Mental status changes 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Migraine 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Mood altered 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Muscle spasms 1.0 0.0 1.0 1.0 0.0 0.0 0.0 Selexipag Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Musculoskeletal chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Musculoskeletal pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Myalgia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Myocardial infarction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Nasal congestion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Nausea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Neck pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Selexipag Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Neuropathy peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Ocular hyperaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Oedema peripheral 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Oropharyngeal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Oxygen saturation decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Pain in extremity 1.0 0.0 1.0 1.0 0.0 0.0 0.0 Selexipag Pain in jaw 1.0 0.0 1.0 1.0 0.0 0.0 0.0 Selexipag Pallor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Paraesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Pericardial effusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Peripheral swelling 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Photophobia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Platelet count decreased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Selexipag Pleural effusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Pollakiuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Poor quality sleep 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Selexipag Productive cough 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Selexipag Pruritus 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Pulmonary fibrosis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Pulmonary hypertension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Pulmonary oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Pyrexia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Rash 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Rash generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Rash pruritic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Red blood cell count decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Selexipag Renal disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Renal failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Respiratory distress 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Respiratory failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Selexipag Respiratory tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Restless legs syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Restlessness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Selexipag Retching 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Selexipag Rhinorrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Sepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Selexipag Sinusitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Skin discolouration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Sneezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Somnolence 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Speech disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Spinal fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Staphylococcal infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Stress 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Selexipag Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Selexipag Swelling 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Swelling face 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Selexipag Syncope 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Tachycardia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Selexipag Thirst 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Tremor 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Troponin increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Unevaluable event 1.0 0.0 1.0 1.0 0.0 0.0 0.0 Selexipag Unresponsive to stimuli 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Upper limb fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Upper respiratory tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Urinary incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Urinary tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Viral infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Vision blurred 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Vomiting 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Weight decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Weight increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selexipag Wheezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Selinexor Anaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selinexor Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Selinexor Decreased appetite 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selinexor Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Selinexor Hyponatraemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selinexor Nausea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selinexor Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Selinexor Thrombocytopenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selinexor Vomiting 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Selinexor Weight decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Semaglutide Abdominal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Semaglutide Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Semaglutide Abdominal pain upper 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Semaglutide Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Semaglutide Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Semaglutide Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Semaglutide Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Semaglutide Back pain 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Semaglutide Blindness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Semaglutide Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Semaglutide Blood glucose increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Semaglutide Cardiac arrest 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Semaglutide Cerebrovascular accident 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Semaglutide Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Semaglutide Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Semaglutide Cholecystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Semaglutide Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Semaglutide Constipation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Semaglutide Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Semaglutide Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Semaglutide Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Semaglutide Diabetic ketoacidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Semaglutide Diarrhoea 0.0 0.0 1.0 0.0 0.0 1.0 0.0 Semaglutide Drug-induced liver injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Semaglutide Eructation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Semaglutide Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Semaglutide Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Semaglutide Flatulence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Semaglutide Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Semaglutide Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Semaglutide Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Semaglutide Headache 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Semaglutide Hyperglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Semaglutide Hyperkalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Semaglutide Hypertension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Semaglutide Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Semaglutide Ileus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Semaglutide Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Semaglutide Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Semaglutide Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Semaglutide Nausea 0.0 0.0 1.0 0.0 0.0 1.0 0.0 Semaglutide Pancreatic carcinoma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Semaglutide Pancreatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Semaglutide Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Semaglutide Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Semaglutide Rectal haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Semaglutide Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Semaglutide Retching 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Semaglutide Sepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Semaglutide Somnolence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Semaglutide Suicidal ideation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Semaglutide Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Semaglutide Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Semaglutide Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Semaglutide Vomiting 0.0 0.0 1.0 0.0 0.0 1.0 0.0 Sertraline hydrochloride Abdominal distension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Abdominal pain 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Abnormal dreams 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Accommodation disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Acne 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sertraline hydrochloride Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Affect lability 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Aggression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Agitation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Agranulocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Akathisia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Alanine aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Sertraline hydrochloride Amnesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Anaemia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Anal incontinence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Angioedema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Anorectal discomfort 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Apathy 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Aphasia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Apnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Arthropathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Atrioventricular block 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Bladder pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Blindness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Blister 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Blood cholesterol increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sertraline hydrochloride Body temperature increased 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Breast enlargement 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sertraline hydrochloride Breast pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sertraline hydrochloride Bundle branch block 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Cardiac disorder 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Sertraline hydrochloride Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sertraline hydrochloride Chest pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Chills 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Cold sweat 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Sertraline hydrochloride Colitis 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Sertraline hydrochloride Coma 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Confusional state 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Coordination abnormal 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Sertraline hydrochloride Cough 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Decreased appetite 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Dehydration 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Delirium 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Delusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Depersonalisation/derealisation disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Depressed level of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Dermatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sertraline hydrochloride Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Diplopia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Disturbance in sexual arousal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Dizziness postural 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Dry skin 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Dysgeusia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Dyskinesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Dysmenorrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Sertraline hydrochloride Dysphagia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Dysphonia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Dyspnoea 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Sertraline hydrochloride Dystonia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Dysuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sertraline hydrochloride Ear pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Electrocardiogram QT prolonged 0.0 1.0 1.0 0.0 1.0 0.0 0.0 Sertraline hydrochloride Epistaxis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Erectile dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Sertraline hydrochloride Eructation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sertraline hydrochloride Erythema 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Erythema multiforme 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Euphoric mood 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Extrapyramidal disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Eye disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Eye haemorrhage 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Eye pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Face oedema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Feeling abnormal 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Sertraline hydrochloride Feeling jittery 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Flat affect 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Flatulence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sertraline hydrochloride Flushing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Galactorrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sertraline hydrochloride Gastritis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Gastroenteritis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Gastrointestinal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Gastrointestinal haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Gastrointestinal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Glaucoma 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Sertraline hydrochloride Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Hallucination 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Hepatic failure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Hernia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sertraline hydrochloride Hiccups 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Hostility 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Hot flush 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Sertraline hydrochloride Hyperaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Hypercholesterolaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sertraline hydrochloride Hyperglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Hypersensitivity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Hypertension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Hypertonia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Hyperventilation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sertraline hydrochloride Hypoaesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Hypoglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Hypokinesia 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Sertraline hydrochloride Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Hypothyroidism 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Hypotonia 0.0 0.0 1.0 0.0 1.0 0.0 0.0 Sertraline hydrochloride Hypoxia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Immune system disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Inappropriate antidiuretic hormone secretion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Insomnia 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Sertraline hydrochloride Intentional self-injury 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Jaundice 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Leukopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Libido decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Libido increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Loss of consciousness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Lymphadenopathy 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Malaise 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Malnutrition 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Mania 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Melaena 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Menorrhagia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Menstruation irregular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sertraline hydrochloride Mental disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Mental impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Metrorrhagia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sertraline hydrochloride Micturition disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sertraline hydrochloride Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Mood swings 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Sertraline hydrochloride Movement disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Muscle contractions involuntary 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Muscle rigidity 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Muscle spasms 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Muscle twitching 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Musculoskeletal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sertraline hydrochloride Myalgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Mydriasis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Myoclonus 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Sertraline hydrochloride Nausea 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Sertraline hydrochloride Neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sertraline hydrochloride Nervous system disorder 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Nervousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sertraline hydrochloride Neuroleptic malignant syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Nightmare 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Sertraline hydrochloride Nocturia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Nystagmus 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Oedema 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Sertraline hydrochloride Oedema peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Oesophagitis 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Orthostatic hypotension 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Osteoarthritis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Otitis media 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Sertraline hydrochloride Pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Pallor 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Palpitations 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Pancytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Paraesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Paranoia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Periorbital oedema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Peripheral ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Photophobia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Photosensitivity reaction 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Sertraline hydrochloride Pollakiuria 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Polyuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Pruritus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Psychotic disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Pulmonary hypertension 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Sertraline hydrochloride Purpura 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Pyelonephritis 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Sertraline hydrochloride Pyrexia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Rash 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Rash maculo-papular 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Rectal haemorrhage 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Seizure 0.0 1.0 1.0 1.0 1.0 0.0 0.0 Sertraline hydrochloride Serotonin syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Sexual dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Sinusitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Skin discolouration 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Skin odour abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Somnolence 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Speech disorder 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Sertraline hydrochloride Stevens-Johnson syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Suicidal ideation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Suicide attempt 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Syncope 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Tachycardia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Tension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Thinking abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Thirst 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Tinnitus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Torsade de pointes 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Toxic epidermal necrolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Transaminases increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Tremor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Urinary incontinence 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Urinary retention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sertraline hydrochloride Urticaria 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Vaginal haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sertraline hydrochloride Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sertraline hydrochloride Vertigo 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Visual field defect 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sertraline hydrochloride Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Sertraline hydrochloride Vomiting 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Weight decreased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sertraline hydrochloride Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Sertraline hydrochloride Withdrawal syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sevelamer Melaena 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sevelamer carbonate Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sevelamer carbonate Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sevelamer carbonate Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sevoflurane Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sevoflurane Anaphylactic reaction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sevoflurane Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sevoflurane Apnoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sevoflurane Arrhythmia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sevoflurane Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sevoflurane Atrial fibrillation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sevoflurane Bacteraemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sevoflurane Blood pressure decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sevoflurane Bradycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sevoflurane Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sevoflurane Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sevoflurane Chest pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sevoflurane Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sevoflurane Confusional state 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sevoflurane Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sevoflurane Delirium 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sevoflurane Dyspnoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sevoflurane Generalised tonic-clonic seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sevoflurane Haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sevoflurane Heart rate increased 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Sevoflurane Hepatic failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sevoflurane Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sevoflurane Laryngospasm 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sevoflurane Muscle rigidity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sevoflurane Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sevoflurane Oliguria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sevoflurane Oxygen saturation decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sevoflurane Pulmonary alveolar haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sevoflurane Pulmonary oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sevoflurane Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sevoflurane Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sevoflurane Septic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sevoflurane Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sevoflurane Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sevoflurane Transaminases increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sevoflurane Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sevoflurane Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sevoflurane Wheezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Acute coronary syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Acute myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Acute respiratory distress syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Acute respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sildenafil Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Atrial fibrillation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sildenafil Blood glucose decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Blood pressure decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Brain injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Cardiac disorder 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Sildenafil Cardiac failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Cardiac failure acute 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Cardiogenic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Cerebral haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Cerebrovascular accident 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Sildenafil Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Chronic obstructive pulmonary disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Circulatory collapse 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Coma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Confusional state 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Conjunctival hyperaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Coronary artery disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Cyanosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Cystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Deafness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sildenafil Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Diarrhoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Dysarthria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Dyspnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Electrocardiogram abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sildenafil Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sildenafil Erythema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sildenafil Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sildenafil Flatulence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Fluid overload 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Fluid retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Flushing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sildenafil Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Gastrooesophageal reflux disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sildenafil Haematochezia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Haemoptysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Heart rate increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Hip fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Hypoxia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sildenafil Interstitial lung disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Ischaemic stroke 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Sildenafil Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Liver disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Loss of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Lung disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Malignant melanoma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Mydriasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Myocardial ischaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Myocarditis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Ocular hyperaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sildenafil Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Oxygen saturation decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Pancytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Photophobia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Pleural effusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Pneumonia aspiration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Premature baby 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sildenafil Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Pulmonary embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Pulmonary hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Renal failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Renal impairment 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Respiratory disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Respiratory distress 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Respiratory tract infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Sepsis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Sinus tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Subarachnoid haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Suicide attempt 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sildenafil Transient ischaemic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Urinary tract infection 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Ventricular fibrillation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Ventricular tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Vision blurred 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Visual acuity reduced 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sildenafil Weight decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sildenafil citrate Blindness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sildenafil citrate Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sildenafil citrate Deafness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Sildenafil citrate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sildenafil citrate Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil citrate Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil citrate Epistaxis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sildenafil citrate Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sildenafil citrate Eye haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sildenafil citrate Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sildenafil citrate Insomnia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sildenafil citrate Myalgia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sildenafil citrate Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sildenafil citrate Nasal congestion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sildenafil citrate Nausea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sildenafil citrate Oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sildenafil citrate Oedema peripheral 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sildenafil citrate Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sildenafil citrate Subarachnoid haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sildenafil citrate Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Silodosin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Silodosin Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Silodosin Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Silodosin Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simeprevir Anaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simeprevir Asthenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Simeprevir Blood bilirubin increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simeprevir Constipation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simeprevir Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simeprevir Dyspnoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Simeprevir Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simeprevir Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simeprevir Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Simeprevir Infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Simeprevir Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simeprevir Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simeprevir Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simeprevir Photosensitivity reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simeprevir Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simeprevir Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simvastatin Abdominal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simvastatin Abdominal distension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Abdominal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Abdominal pain upper 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Abnormal dreams 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Acute coronary syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simvastatin Acute hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Acute kidney injury 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Simvastatin Acute myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Aggression 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Simvastatin Agitation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Alanine aminotransferase increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Simvastatin Altered state of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Amnesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Anaemia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Anal incontinence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Anuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Aphasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Aplastic anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Appendicitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Arthralgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Arthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Arthropathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Aspartate aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Ataxia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Atrial fibrillation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Atrioventricular block complete 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Back pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Balance disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Basal cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simvastatin Blister 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Blood alkaline phosphatase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Blood cholesterol increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Blood creatine phosphokinase increased 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Simvastatin Blood creatinine increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Blood glucose increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Blood lactate dehydrogenase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Blood pressure decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Blood urine present 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Body temperature increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Bone pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simvastatin Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simvastatin Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Burning sensation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin C-reactive protein increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Cardiac disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Cardiomyopathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simvastatin Cerebral haemorrhage 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Cerebral infarction 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Simvastatin Chest discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Chest pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Cholestasis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Chromaturia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Chronic kidney disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Circulatory collapse 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Coagulopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Cognitive disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Cold sweat 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Colitis ischaemic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Confusional state 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Constipation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Contusion 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Cough 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Deep vein thrombosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Dehydration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Depressed mood 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Dermatitis bullous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simvastatin Dermatitis exfoliative 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Diabetes mellitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Diplopia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Disease progression 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Disseminated intravascular coagulation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Simvastatin Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Drug abuse 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Drug eruption 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simvastatin Drug hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Drug interaction 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Simvastatin Drug intolerance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Drug-induced liver injury 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Dry eye 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Duodenal ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Dysarthria 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Simvastatin Dysgeusia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Dyskinesia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Dyspepsia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Dysphagia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Dyspnoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Dyspnoea exertional 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Dysstasia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Dysuria 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Eating disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Ecchymosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Eczema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Electrocardiogram QT prolonged 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Enteritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simvastatin Eosinophilia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Epilepsy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Epistaxis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Erectile dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Erythema 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Eye irritation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Eye pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Eye swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simvastatin Face oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Facial paralysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Feeling cold 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Flank pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Flatulence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Fluid retention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Flushing 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Fungal skin infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Furuncle 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Gait disturbance 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Gastritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Gastrointestinal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Gout 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simvastatin Gynaecomastia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simvastatin Haematochezia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Haematoma 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Haematuria 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Haemoptysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Haemorrhage intracranial 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Heart rate increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simvastatin Heart rate irregular 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Hemiparesis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Hepatic function abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Hepatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Hepatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Hepatitis cholestatic 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Hepatocellular injury 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Simvastatin Hepatomegaly 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Herpes zoster 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Hot flush 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simvastatin Hypercalcaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Hypercholesterolaemia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Hyperglycaemia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Hyperkalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Simvastatin Hyperthyroidism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Hypoglycaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Hypokalaemia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Simvastatin Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Hypothermia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Hypotonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Hypoxia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Inflammation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Influenza 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simvastatin Influenza like illness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Intentional self-injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Interstitial lung disease 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Irritability 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simvastatin Irritable bowel syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simvastatin Ischaemic stroke 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Jaundice 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Simvastatin Joint stiffness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Joint swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Lactic acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Large intestine perforation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Lethargy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Leukocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Leukopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Libido decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Limb discomfort 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Simvastatin Lip swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simvastatin Lipase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Liver disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Liver function test abnormal 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Simvastatin Liver function test increased 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Simvastatin Liver injury 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Localised infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Lower respiratory tract infection 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Lung disorder 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Simvastatin Lymphadenopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Melaena 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Metabolic acidosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Migraine 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Mobility decreased 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Mood altered 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Movement disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Muscle atrophy 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Muscle rigidity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simvastatin Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Muscle tightness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simvastatin Muscle twitching 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Musculoskeletal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simvastatin Musculoskeletal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Musculoskeletal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Musculoskeletal stiffness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Myocardial infarction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Myocardial ischaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Myopathy 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Myositis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Neck pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Simvastatin Neoplasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Nervousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simvastatin Neuralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Nightmare 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Simvastatin Nocturia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Obesity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Oedema 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Oedema peripheral 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Oliguria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Orthostatic hypotension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Oxygen saturation decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Pain in extremity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Pallor 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Palpitations 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Pancreatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Pancytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Paralysis 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Paranoia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Paresis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Parkinson's disease 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Pericarditis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Periorbital oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Peripheral coldness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Peripheral swelling 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Peritonitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Personality change 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Photosensitivity reaction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Platelet count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simvastatin Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Pleurisy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Pneumonia 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Pneumonia aspiration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Pollakiuria 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Polyneuropathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Poor quality sleep 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Simvastatin Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Simvastatin Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Proteinuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Psoriasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Pulmonary embolism 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Pulmonary fibrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Pyrexia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Rash 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Rash erythematous 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Simvastatin Rash generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Rash macular 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Simvastatin Rash papular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simvastatin Rash pruritic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Renal disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Renal failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Renal impairment 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Renal tubular necrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Respiratory failure 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Restless legs syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simvastatin Retinal detachment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simvastatin Rhabdomyolysis 0.0 1.0 1.0 1.0 0.0 1.0 0.0 Simvastatin Seizure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Sensory disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Sensory loss 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Sexual dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simvastatin Skin discolouration 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Simvastatin Skin exfoliation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simvastatin Skin irritation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Skin lesion 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Simvastatin Sleep disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Somnolence 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Sopor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Speech disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Stress 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Subarachnoid haemorrhage 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Subdural haematoma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Swelling face 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simvastatin Swollen tongue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Tachypnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin Tenderness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Tendon rupture 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Tendonitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simvastatin Throat tightness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simvastatin Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Thrombosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Toxic epidermal necrolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Transaminases increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Transient ischaemic attack 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Simvastatin Tremor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Unresponsive to stimuli 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Upper gastrointestinal haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Upper respiratory tract infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Urinary incontinence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Simvastatin Urinary retention 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Urinary tract infection 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Urticaria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Vertigo 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Vision blurred 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Visual acuity reduced 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Visual impairment 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Simvastatin Vomiting 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Weight decreased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Simvastatin Wheezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Simvastatin White blood cell count increased 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Siponimod Abdominal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Siponimod Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Siponimod Arthralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Siponimod Balance disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Siponimod Basal cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Siponimod Blood pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Siponimod Bradycardia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Siponimod Burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Siponimod Contusion 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Siponimod Decreased appetite 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Siponimod Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Siponimod Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Siponimod Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Siponimod Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Siponimod Feeling abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Siponimod Gait disturbance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Siponimod Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Siponimod Heart rate decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Siponimod Hepatic enzyme increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Siponimod Hypoaesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Siponimod Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Siponimod Joint swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Siponimod Lymphocyte count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Siponimod Lymphopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Siponimod Memory impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Siponimod Mobility decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Siponimod Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Siponimod Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Siponimod Neck pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Siponimod Pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Siponimod Paraesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Siponimod Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Siponimod Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Siponimod Pyrexia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Siponimod Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Siponimod Tremor 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Siponimod Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Siponimod Vertigo 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Siponimod Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Siponimod Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Siponimod Weight decreased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Siponimod Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Siponimod White blood cell count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sirolimus Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Acne 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sirolimus Acute kidney injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sirolimus Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Alopecia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sirolimus Ascites 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sirolimus Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Asthma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Blood bilirubin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Blood cholesterol increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Blood magnesium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sirolimus Cardiac disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sirolimus Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Confusional state 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sirolimus Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sirolimus Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Disease progression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sirolimus Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Feeling abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Fluid retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Gout 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Haemoglobin decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Haemoptysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sirolimus Hernia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Herpes zoster 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Hyperlipidaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sirolimus Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Hypoaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Hyponatraemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sirolimus Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Hypoxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sirolimus Immune system disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sirolimus Leukopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sirolimus Liver disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Liver function test abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sirolimus Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sirolimus Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Melaena 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Memory impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Metabolic acidosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sirolimus Mucosal inflammation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sirolimus Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sirolimus Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sirolimus Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sirolimus Neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sirolimus Oral candidiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sirolimus Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Peritonitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Pleural effusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sirolimus Pneumonia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Pneumonitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Pneumothorax 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Pulmonary embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Pulmonary fibrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sirolimus Pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Renal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sirolimus Respiratory distress 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sirolimus Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sirolimus Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sirolimus Sinusitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Small intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Swollen tongue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Transaminases increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sirolimus Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Unresponsive to stimuli 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sirolimus Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Sirolimus Weight increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sitagliptin Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sitagliptin Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sitagliptin Cerebral infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sitagliptin Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sitagliptin Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sitagliptin Liver disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sitagliptin Pancreatic carcinoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sitagliptin Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sitagliptin Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sitagliptin Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sitagliptin Renal impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sitagliptin Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sitagliptin phosphate Abdominal pain 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Sitagliptin phosphate Acute kidney injury 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Sitagliptin phosphate Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sitagliptin phosphate Constipation 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Sitagliptin phosphate Diarrhoea 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Sitagliptin phosphate Headache 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Sitagliptin phosphate Hepatic enzyme increased 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Sitagliptin phosphate Hypoglycaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Sitagliptin phosphate Nasopharyngitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sitagliptin phosphate Nausea 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Sitagliptin phosphate Oedema peripheral 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Sitagliptin phosphate Pancreatitis acute 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Sitagliptin phosphate Rash 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Sitagliptin phosphate Skin exfoliation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sitagliptin phosphate Upper respiratory tract infection 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Sitagliptin phosphate Urticaria 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sitagliptin phosphate Vomiting 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Sitagliptin phosphate White blood cell count increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sodium bicarbonate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sodium bicarbonate Haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium chloride Abdominal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Acute kidney injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium chloride Acute respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Agitation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium chloride Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Arthralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium chloride Asthenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Atrioventricular block complete 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Back pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium chloride Blood pressure decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Blood pressure increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium chloride Bone marrow failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Brain oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium chloride C-reactive protein increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium chloride Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Cardiogenic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Chest discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Chills 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Confusional state 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Cyanosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Death 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium chloride Diarrhoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Dyspepsia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium chloride Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Erythema 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Sodium chloride Extravasation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium chloride Flushing 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Sodium chloride Generalised tonic-clonic seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium chloride Haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium chloride Haemorrhage intracranial 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sodium chloride Hyperkalaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Hypernatraemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Hypokalaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Hyponatraemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium chloride Influenza like illness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium chloride Liver function test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium chloride Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Lower respiratory tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium chloride Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Mental status changes 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Metabolic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Nervous system disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Oropharyngeal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium chloride Oxygen saturation decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sodium chloride Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sodium chloride Platelet count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium chloride Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium chloride Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium chloride Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium chloride Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Sodium chloride Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Sepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Sodium chloride Septic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Shock 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium chloride Sinusitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium chloride Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Speech disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium chloride Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium chloride Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Throat irritation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Tremor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Unresponsive to stimuli 1.0 1.0 0.0 0.0 0.0 1.0 0.0 Sodium chloride Ventricular fibrillation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium chloride Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium ferric gluconate complex Abdominal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium ferric gluconate complex Abdominal pain 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium ferric gluconate complex Abdominal pain upper 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium ferric gluconate complex Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium ferric gluconate complex Anaphylactic shock 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium ferric gluconate complex Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium ferric gluconate complex Back pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium ferric gluconate complex Blood pressure decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium ferric gluconate complex Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium ferric gluconate complex Chest discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium ferric gluconate complex Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium ferric gluconate complex Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium ferric gluconate complex Diarrhoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Sodium ferric gluconate complex Discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium ferric gluconate complex Dizziness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Sodium ferric gluconate complex Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium ferric gluconate complex Feeling abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium ferric gluconate complex Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium ferric gluconate complex Hypoaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium ferric gluconate complex Hypotension 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Sodium ferric gluconate complex Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium ferric gluconate complex Nausea 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Sodium ferric gluconate complex Paraesthesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium ferric gluconate complex Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sodium ferric gluconate complex Swollen tongue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium ferric gluconate complex Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium ferric gluconate complex Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium ferric gluconate complex Unresponsive to stimuli 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium ferric gluconate complex Urticaria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium ferric gluconate complex Vomiting 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Sodium oxybate Abdominal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Abdominal distension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Abdominal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Abdominal pain upper 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Abnormal dreams 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium oxybate Acne 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Affect lability 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sodium oxybate Agitation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Amnesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Anaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Anaphylactic reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Anger 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Angina pectoris 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Anuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium oxybate Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Apathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Aphasia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Apnoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Appetite disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Arrhythmia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Arthralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Arthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Arthropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Aspiration 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Asthenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Asthma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Ataxia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sodium oxybate Atrial fibrillation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Back pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Balance disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Blood cholesterol increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Blood glucose increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Blood potassium decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Blood pressure abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Blood pressure decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Blood pressure fluctuation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Blood pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Bone disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sodium oxybate Bone pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium oxybate Bradyphrenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Brain injury 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sodium oxybate Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Bronchitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium oxybate Cardiac disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium oxybate Cardiac murmur 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Cardio-respiratory arrest 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium oxybate Cardiomyopathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Carpal tunnel syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium oxybate Chest discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Chest pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Chills 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Choking 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Cholelithiasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Chronic kidney disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Chronic obstructive pulmonary disease 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Sodium oxybate Cognitive disorder 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Sodium oxybate Cold sweat 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Colitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Colitis ischaemic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium oxybate Colitis ulcerative 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Coma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium oxybate Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sodium oxybate Confusional state 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Constipation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Contusion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Coronary artery disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Crohn's disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Crying 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Cyst 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Cystitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sodium oxybate Decreased appetite 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Dehydration 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Delusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium oxybate Dementia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sodium oxybate Dental caries 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Depressed level of consciousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Depressed mood 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Diarrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Diplopia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Disorientation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Disturbance in attention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Diverticulitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Drug abuse 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Drug dependence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Drug hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Dry eye 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Dry skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Dry throat 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Dysgeusia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Dyskinesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Dysmenorrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Dysphagia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Dysphonia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Dyspnoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Dystonia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Ear infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Ear pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Eating disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium oxybate Emotional disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Epilepsy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Epistaxis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Euphoric mood 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Eye disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Eye irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Feeling abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Feeling cold 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Feeling hot 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Feeling jittery 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Fluid retention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Flushing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Folliculitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Fracture 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Fungal infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Fungal skin infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Gait disturbance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Gallbladder disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Gastric disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Gastric ulcer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Gastritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Gastroenteritis viral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Gastrointestinal disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Gastrooesophageal reflux disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Generalised tonic-clonic seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Glossodynia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Gout 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Haematochezia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Haematuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Haemorrhoids 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Hallucination 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Heart rate decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Heart rate increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Hemiparesis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Hepatic cirrhosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Hepatic enzyme increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Hepatic steatosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Hernia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Herpes zoster 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Hot flush 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Hyperhidrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Hyperlipidaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Hypersomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Hyperthyroidism 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Hypoacusis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Hypoaesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Hypokalaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Hypokinesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Hypophagia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sodium oxybate Hypotension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Hypothyroidism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Incontinence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Increased appetite 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Inflammation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Influenza 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Influenza like illness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Intervertebral disc protrusion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium oxybate Irritability 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Irritable bowel syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Joint swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Lacrimation increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Laryngitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium oxybate Libido increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Limb discomfort 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Sodium oxybate Liver function test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium oxybate Local swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Localised infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sodium oxybate Loss of consciousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Lower respiratory tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Lymphadenopathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Malaise 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Malignant melanoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Mania 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium oxybate Memory impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Mental impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium oxybate Middle insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Migraine 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Mood altered 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Movement disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sodium oxybate Muscle spasms 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Muscle tightness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Muscle twitching 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Muscular weakness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Musculoskeletal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Musculoskeletal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Musculoskeletal stiffness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Nasal congestion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Nasal dryness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Nasopharyngitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Neck pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Nephrolithiasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Nervousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Neuralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Night sweats 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Nightmare 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Nocturia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Obesity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Ocular hyperaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Oedema peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Oesophageal ulcer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Oropharyngeal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Orthostatic hypotension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Osteoarthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Osteoporosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Sodium oxybate Pain in extremity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Pain in jaw 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Panic attack 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Paraesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Paraesthesia oral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Paralysis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sodium oxybate Paranoia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Parkinson's disease 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Sodium oxybate Parosmia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Peripheral coldness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Peripheral swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Photophobia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Pneumonia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Pollakiuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Polyp 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Polyuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Poor quality sleep 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Prostate cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Psoriasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Psychomotor hyperactivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Psychotic disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Pulmonary embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium oxybate Pulmonary hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Pulmonary mass 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Pyrexia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Renal failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Respiratory disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sodium oxybate Respiratory tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Restless legs syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Restlessness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Retching 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium oxybate Rheumatoid arthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Rhinorrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Salivary hypersecretion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Sciatica 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Sodium oxybate Sedation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Sepsis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium oxybate Serotonin syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Sinus congestion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Sinus disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Sinusitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Skin burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Skin disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Skin odour abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Sleep apnoea syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Sleep disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Sluggishness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Sneezing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Somnolence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Speech disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Stomatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Stress 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Suicidal ideation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Suicide attempt 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium oxybate Supraventricular tachycardia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Swelling face 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Syncope 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Systemic lupus erythematosus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Tachycardia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Tardive dyskinesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Tendon rupture 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Tendonitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Thinking abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Thirst 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Throat irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Thrombosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Tinnitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Tooth abscess 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Tooth disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Toothache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Transient ischaemic attack 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Tremor 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Ulcer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Unevaluable event 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Unresponsive to stimuli 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Upper limb fracture 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Upper respiratory tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Urinary incontinence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Urinary retention 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Sodium oxybate Urinary tract disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Urinary tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Ventricular extrasystoles 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Vertigo 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Viral infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sodium oxybate Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Vomiting 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Weight decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Wheezing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium oxybate Withdrawal syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sodium phenylbutyrate Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium polystyrene sulfonate Colitis ischaemic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium polystyrene sulfonate Hypokalaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sodium zirconium cyclosilicate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sodium zirconium cyclosilicate Fluid overload 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium zirconium cyclosilicate Hyperkalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sodium zirconium cyclosilicate Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sofosbuvir Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sofosbuvir Acute coronary syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Acute hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Acute respiratory failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sofosbuvir Alanine aminotransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Anger 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sofosbuvir Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sofosbuvir Asthma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sofosbuvir Back pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Blister 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Blood pressure decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Cardiac disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Cardiac failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Cardiac failure congestive 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sofosbuvir Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Chronic kidney disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Coagulopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sofosbuvir Colitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sofosbuvir Coma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sofosbuvir Contusion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Crying 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sofosbuvir Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Disorientation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Disseminated intravascular coagulation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Drug resistance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Dry eye 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Dry skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Dyspnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Sofosbuvir Eczema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Emotional disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Encephalopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Epistaxis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Erythema multiforme 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Sofosbuvir Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sofosbuvir Fluid overload 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sofosbuvir Fluid retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sofosbuvir Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sofosbuvir Gastritis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sofosbuvir Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Gout 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sofosbuvir Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sofosbuvir Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Hepatic cirrhosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Hepatic encephalopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Hepatic failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sofosbuvir Hyperbilirubinaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sofosbuvir Hypotension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Ileus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sofosbuvir Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Irritability 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Jaundice 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Lactic acidosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Liver disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Lung disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Lung neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Lymphoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Melaena 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sofosbuvir Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sofosbuvir Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sofosbuvir Migraine 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sofosbuvir Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sofosbuvir Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Nervousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Neutrophil count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Oedema peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sofosbuvir Oropharyngeal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sofosbuvir Pancreatitis acute 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Pancytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Paraesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sofosbuvir Photosensitivity reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sofosbuvir Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Pulmonary embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Pyrexia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Sofosbuvir Rash 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sofosbuvir Red blood cell count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Shock haemorrhagic 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Sinus bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sofosbuvir Sinusitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Stress 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sofosbuvir Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Thrombosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Tinnitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Transaminases increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Treatment failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sofosbuvir Upper gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sofosbuvir Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Viral infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sofosbuvir Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Solifenacin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Solifenacin Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Solifenacin Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Solifenacin Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Solifenacin Malaise 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Solifenacin Pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Solifenacin Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Solifenacin Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Solifenacin succinate Abdominal pain upper 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Solifenacin succinate Constipation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Solifenacin succinate Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Solifenacin succinate Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Solifenacin succinate Dry eye 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Solifenacin succinate Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Solifenacin succinate Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Solifenacin succinate Dysphonia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Solifenacin succinate Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Solifenacin succinate Gastrooesophageal reflux disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Solifenacin succinate Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Solifenacin succinate Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Solifenacin succinate Oedema peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Solifenacin succinate Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Solifenacin succinate Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Solifenacin succinate Urinary retention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Solifenacin succinate Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Sonidegib Alopecia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sonidegib Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sonidegib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sonidegib Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sonidegib Diarrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sonidegib Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sonidegib Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sonidegib Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sonidegib Vomiting 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Abasia 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Sorafenib Abdominal discomfort 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Abdominal distension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Abdominal pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Abdominal pain upper 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Acute coronary syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Acute hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Acute myeloid leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Acute myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Acute respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Alanine aminotransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Altered state of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Anal incontinence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Anuria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Apathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Aphasia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Aphthous ulcer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Aspartate aminotransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Asthenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Azotaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Back pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Balance disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Blister 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sorafenib Blood albumin decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Blood bilirubin increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Blood count abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Blood creatine phosphokinase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Blood creatinine increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Blood glucose decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Blood lactate dehydrogenase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Blood potassium increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Blood pressure decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Blood pressure fluctuation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Blood urine present 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Body temperature increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Bone marrow failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Bronchitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Cardiac disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Cardiac failure acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Cardiotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sorafenib Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Cerebral infarction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sorafenib Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Cholelithiasis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Chromaturia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Circulatory collapse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Confusional state 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Constipation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Coordination abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sorafenib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Decubitus ulcer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Dehydration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Delirium 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Depressed level of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Diabetes mellitus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Diarrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Sorafenib Disorientation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Disseminated intravascular coagulation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Diverticulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Dizziness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Drug eruption 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Dry mouth 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Dry skin 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Dysarthria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Dysgeusia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Dysphagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Dysphonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Dysstasia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Dysuria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Eating disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Encephalopathy 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Epistaxis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Erythema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Erythema multiforme 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Face oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Faeces discoloured 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Fatigue 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Febrile neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Feeding disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Feeling abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Feeling cold 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Feeling hot 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Fluid retention 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Frequent bowel movements 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Gastric haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Gastrointestinal disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Gastrooesophageal reflux disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Generalised oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Gingival bleeding 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Glossodynia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Haematemesis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Haematochezia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Haematuria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Haemoglobin decreased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Haemoptysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Haemorrhoids 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Headache 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Hepatic cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Hepatic cirrhosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Hepatic encephalopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Hepatic enzyme increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Hepatic function abnormal 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Hepatitis cholestatic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Hepatomegaly 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Hiccups 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Hyperbilirubinaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Hyperhidrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Hypersomnia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Hypertension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Hypocalcaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Hypoglycaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Hyponatraemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Hypophagia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Hypotension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Hypothyroidism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sorafenib Hypoxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Ill-defined disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Inappropriate antidiuretic hormone secretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Increased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Inflammation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Influenza like illness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Insomnia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Interstitial lung disease 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Irritability 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Ischaemic stroke 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Jaundice 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Laboratory test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Large intestine perforation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Left ventricular dysfunction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Lethargy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Leukocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Lipase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Liver disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Liver function test abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Liver function test increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Liver injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sorafenib Loss of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Lung disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Lung infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Lymphadenopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Malaise 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Sorafenib Melaena 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Metabolic acidosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Metastases to central nervous system 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Metastases to liver 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Metastases to lung 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Sorafenib Mobility decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Motor dysfunction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Mouth ulceration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Mucosal inflammation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Muscular weakness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Myalgia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Myocardial ischaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Nausea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Neoplasm 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Oedema peripheral 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Oropharyngeal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sorafenib Oropharyngeal pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Pain in extremity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sorafenib Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Pancytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Peripheral coldness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Peripheral swelling 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Peritonitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Platelet count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Pleural effusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Pollakiuria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Proctalgia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Productive cough 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Proteinuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sorafenib Prothrombin time prolonged 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Pruritus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Psoriasis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Pulmonary embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Pulmonary mass 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Pulmonary oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Purpura 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Pyrexia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Rash 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Rash vesicular 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Rectal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Renal disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Renal impairment 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Respiratory disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Respiratory distress 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Respiratory tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Seizure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Skin burning sensation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Skin irritation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Skin reaction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Somnolence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Speech disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Stevens-Johnson syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Stomatitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Stress 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sorafenib Subarachnoid haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Swelling 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Thrombocytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Tinnitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sorafenib Tumour lysis syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Ulcer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Unevaluable event 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Unresponsive to stimuli 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Upper gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Urinary retention 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Urinary tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sorafenib Vomiting 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib Weight decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib Wheezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sorafenib White blood cell count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sorafenib White blood cell count increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sotalol Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sotalol Arrhythmia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sotalol Blood pressure decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sotalol Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sotalol Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sotalol Cardiogenic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sotalol Coma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sotalol Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sotalol Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sotalol Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sotalol Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sotalol Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sotalol Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sotalol Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Sotalol Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sotalol Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sotalol Renal failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sotalol Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sotalol Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sotalol Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sotalol Torsade de pointes 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sotalol Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sotalol Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sotalol hydrochloride Electrocardiogram QT prolonged 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sotalol hydrochloride Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sotalol hydrochloride Torsade de pointes 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Spironolactone Abdominal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Spironolactone Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Acute kidney injury 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Spironolactone Acute myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Spironolactone Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Agranulocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Spironolactone Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Anuria 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Spironolactone Arrhythmia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Spironolactone Arthralgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Spironolactone Ascites 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Asthenia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Spironolactone Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Atrioventricular block 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Spironolactone Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Blood creatinine increased 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Spironolactone Blood pressure decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Blood urea increased 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Spironolactone Bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Breast pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Spironolactone Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Spironolactone Cardiac failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Cardiogenic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Spironolactone Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Cerebral haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Chronic kidney disease 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Spironolactone Circulatory collapse 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Spironolactone Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Spironolactone Confusional state 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Spironolactone Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Depressed level of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Depression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Spironolactone Diarrhoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Dizziness 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Spironolactone Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Spironolactone Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Spironolactone Dyspnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Dyspnoea exertional 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Electrocardiogram abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Electrolyte imbalance 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Epilepsy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Spironolactone Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Generalised oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Gynaecomastia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Spironolactone Haematemesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Haematuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Spironolactone Hepatic cirrhosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Spironolactone Hepatic encephalopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Hepatitis cholestatic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Hyperglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Hyperkalaemia 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Spironolactone Hypocalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Hypomagnesaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Hypovolaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Inappropriate antidiuretic hormone secretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Lactic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Spironolactone Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Leukocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Leukopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Malaise 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Spironolactone Melaena 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Spironolactone Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Metabolic acidosis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Mouth ulceration 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Spironolactone Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Spironolactone Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Spironolactone Muscular weakness 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Spironolactone Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Pallor 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Spironolactone Palpitations 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Spironolactone Pericardial effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Pleural effusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Polyuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Spironolactone Pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Pyrexia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Renal failure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Renal impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Renal tubular necrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Respiratory tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Spironolactone Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Spironolactone Shock 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Stevens-Johnson syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Spironolactone Subarachnoid haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Spironolactone Syncope 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Tachypnoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Spironolactone Toxic epidermal necrolysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Spironolactone Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Vascular purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Ventricular arrhythmia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Spironolactone Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Spironolactone Weight increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Stavudine Anaemia 0.0 0.0 1.0 0.0 1.0 0.0 0.0 Stavudine Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Stavudine Hepatic function abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Stavudine Hypertriglyceridaemia 0.0 0.0 1.0 0.0 1.0 0.0 0.0 Stavudine Lactic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Stavudine Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Stavudine Neutropenia 0.0 0.0 1.0 0.0 1.0 0.0 0.0 Stiripentol Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Stiripentol Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Stiripentol Seizure 0.0 0.0 1.0 0.0 0.0 0.0 1.0 Stiripentol Somnolence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Stiripentol Status epilepticus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Stiripentol Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Succinylcholine Cardiac arrest 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Succinylcholine Tachycardia 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Succinylcholine chloride Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Succinylcholine chloride Hyperkalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sucralfate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sugammadex Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Sugammadex Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sugammadex Asthenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sugammadex Atrial fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sugammadex Atrioventricular block complete 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sugammadex Blood pressure decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sugammadex Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sugammadex Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sugammadex Cardiac arrest 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sugammadex Cardio-respiratory arrest 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sugammadex Death 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sugammadex Drug hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sugammadex Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sugammadex Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sugammadex Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sugammadex Hypoxia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sugammadex Laryngeal oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sugammadex Muscle spasms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sugammadex Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sugammadex Oxygen saturation decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sugammadex Pulmonary oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sugammadex Respiratory arrest 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sugammadex Respiratory depression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sugammadex Shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sugammadex Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sugammadex Ventricular fibrillation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sugammadex Ventricular tachycardia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sugammadex sodium Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sugammadex sodium Cardiac arrest 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sulfasalazine Abdominal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sulfasalazine Acute hepatic failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sulfasalazine Acute kidney injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sulfasalazine Agranulocytosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Sulfasalazine Alanine aminotransferase increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sulfasalazine Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sulfasalazine Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sulfasalazine Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Sulfasalazine Arthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sulfasalazine Arthropathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sulfasalazine Aspartate aminotransferase increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sulfasalazine Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sulfasalazine Basal cell carcinoma 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sulfasalazine Blood creatinine increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sulfasalazine Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sulfasalazine Chills 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sulfasalazine Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sulfasalazine Colitis ulcerative 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sulfasalazine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sulfasalazine Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sulfasalazine Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sulfasalazine Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sulfasalazine Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sulfasalazine Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sulfasalazine Disease progression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sulfasalazine Drug eruption 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sulfasalazine Drug hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sulfasalazine Drug intolerance 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Sulfasalazine Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Sulfasalazine Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sulfasalazine Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sulfasalazine Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sulfasalazine Erythema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sulfasalazine Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sulfasalazine Febrile neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sulfasalazine Feeling abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sulfasalazine Gait disturbance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sulfasalazine Gamma-glutamyltransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sulfasalazine Gastrointestinal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sulfasalazine Gastrooesophageal reflux disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sulfasalazine Haematochezia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sulfasalazine Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sulfasalazine Haemolysis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sulfasalazine Haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sulfasalazine Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sulfasalazine Hepatic enzyme abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sulfasalazine Hepatic function abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sulfasalazine Hepatic steatosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sulfasalazine Hepatocellular injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Sulfasalazine Hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sulfasalazine Hypoaesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sulfasalazine Infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sulfasalazine Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sulfasalazine Joint stiffness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sulfasalazine Joint swelling 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Sulfasalazine Leukocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sulfasalazine Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sulfasalazine Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sulfasalazine Mobility decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sulfasalazine Muscle spasms 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sulfasalazine Musculoskeletal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sulfasalazine Musculoskeletal stiffness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sulfasalazine Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sulfasalazine Neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sulfasalazine Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sulfasalazine Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sulfasalazine Nodule 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sulfasalazine Osteoarthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sulfasalazine Pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Sulfasalazine Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sulfasalazine Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sulfasalazine Pancytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sulfasalazine Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sulfasalazine Pharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sulfasalazine Photophobia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sulfasalazine Psoriasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sulfasalazine Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Sulfasalazine Rash 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sulfasalazine Rash generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sulfasalazine Rash macular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sulfasalazine Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sulfasalazine Rash pruritic 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sulfasalazine Red blood cell sedimentation rate increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sulfasalazine Respiratory disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sulfasalazine Respiratory failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sulfasalazine Rheumatoid arthritis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Sulfasalazine Sleep disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sulfasalazine Somnolence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sulfasalazine Stevens-Johnson syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sulfasalazine Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sulfasalazine Tinnitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sulfasalazine Toxic epidermal necrolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sulfasalazine Transaminases increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sulfasalazine Treatment failure 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Sulfasalazine Tremor 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sulfasalazine Urinary tract infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sulfasalazine Urticaria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sulfasalazine Vomiting 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Sulfur hexafluoride Anaphylactic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sulfur hexafluoride Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sulfur hexafluoride Feeling hot 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sulfur hexafluoride Flushing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sulfur hexafluoride Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sulfur hexafluoride Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sulfur hexafluoride Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sulfur hexafluoride Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sulfur hexafluoride Paraesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sulfur hexafluoride Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sulindac Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sumatriptan Abdominal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sumatriptan Acute coronary syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sumatriptan Aggression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sumatriptan Agitation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sumatriptan Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sumatriptan Angina pectoris 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sumatriptan Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sumatriptan Aphasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sumatriptan Arthralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sumatriptan Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sumatriptan Blood pressure increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sumatriptan Bradycardia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sumatriptan Chest discomfort 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Sumatriptan Chest pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sumatriptan Colitis ischaemic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sumatriptan Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sumatriptan Confusional state 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sumatriptan Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sumatriptan Diplopia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sumatriptan Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Sumatriptan Dysarthria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sumatriptan Dysgeusia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sumatriptan Dysphagia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sumatriptan Dyspnoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sumatriptan Ear pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sumatriptan Feeling abnormal 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Sumatriptan Haematemesis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sumatriptan Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sumatriptan Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sumatriptan Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sumatriptan Hypertension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sumatriptan Hypoglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sumatriptan Hypotension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sumatriptan Joint stiffness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sumatriptan Limb discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sumatriptan Malaise 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sumatriptan Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sumatriptan Muscle spasms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sumatriptan Muscle tightness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sumatriptan Muscle twitching 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sumatriptan Musculoskeletal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sumatriptan Musculoskeletal stiffness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sumatriptan Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sumatriptan Myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sumatriptan Nausea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sumatriptan Neck pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sumatriptan Oropharyngeal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sumatriptan Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sumatriptan Pain in jaw 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sumatriptan Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sumatriptan Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sumatriptan Peripheral ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sumatriptan Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sumatriptan Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sumatriptan Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sumatriptan Raynaud's phenomenon 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sumatriptan Seizure 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sumatriptan Serotonin syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sumatriptan Speech disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sumatriptan Subarachnoid haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sumatriptan Swelling face 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sumatriptan Syncope 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sumatriptan Throat tightness 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Sumatriptan Ventricular fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sumatriptan Vertigo 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sumatriptan Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sumatriptan Vomiting 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Sumatriptan Weight increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sumatriptan succinate Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sumatriptan succinate Burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sumatriptan succinate Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sumatriptan succinate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sumatriptan succinate Discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sumatriptan succinate Erythema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sumatriptan succinate Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sumatriptan succinate Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sumatriptan succinate Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sumatriptan succinate Palpitations 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sumatriptan succinate Paraesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sumatriptan succinate Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sumatriptan succinate Skin exfoliation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Sumatriptan succinate Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Sunitinib Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sunitinib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sunitinib malate Abdominal pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Alopecia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Asthenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Back pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Blood albumin decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sunitinib malate Blood alkaline phosphatase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sunitinib malate Blood bilirubin increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sunitinib malate Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Blood glucose decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Blood magnesium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Blood potassium increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Blood sodium decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sunitinib malate Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Constipation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Cough 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Decreased appetite 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Diarrhoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Dry mouth 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Dry skin 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Dysgeusia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Epistaxis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Fatigue 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Glossodynia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Haemoglobin decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Influenza like illness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Lymphocyte count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sunitinib malate Nausea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Neutrophil count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sunitinib malate Oedema peripheral 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sunitinib malate Oral pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Oropharyngeal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Platelet count decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Proteinuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Sunitinib malate Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Pulmonary embolism 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Pyrexia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sunitinib malate Skin discolouration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Sunitinib malate Stomatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Sunitinib malate Transient ischaemic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Vomiting 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Sunitinib malate Weight decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Suvorexant Abnormal dreams 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Suvorexant Amnesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Suvorexant Anxiety 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Suvorexant Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Suvorexant Completed suicide 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Suvorexant Death 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Suvorexant Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Suvorexant Delirium 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Suvorexant Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Suvorexant Disturbance in attention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Suvorexant Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Suvorexant Dyspnoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Suvorexant Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Suvorexant Fear 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Suvorexant Feeling abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Suvorexant Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Suvorexant Hallucination 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Suvorexant Hallucination, auditory 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Suvorexant Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Suvorexant Heart rate increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Suvorexant Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Suvorexant Irritability 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Suvorexant Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Suvorexant Movement disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Suvorexant Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Suvorexant Nightmare 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Suvorexant Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Suvorexant Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Suvorexant Paralysis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Suvorexant Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Suvorexant Seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Suvorexant Sleep disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Suvorexant Somnolence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Suvorexant Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Suvorexant Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Suvorexant Tremor 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tacrolimus Abdominal distension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Abdominal pain lower 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tacrolimus Abscess 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Acne 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Acute coronary syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Acute hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Acute myeloid leukaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Acute myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Acute respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Agitation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Agranulocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Alanine aminotransferase increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Alopecia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Altered state of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Amnesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Tacrolimus Anaphylactic shock 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tacrolimus Angioedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tacrolimus Angiopathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tacrolimus Anuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Aphasia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Arrhythmia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Arthralgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Aspiration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Asthenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Asthma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Ataxia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Atelectasis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Atrial fibrillation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Atrial septal defect 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Tacrolimus Back pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Bacteraemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Bacterial infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Balance disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Basal cell carcinoma 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Tacrolimus Blindness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Blood alkaline phosphatase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Blood cholesterol increased 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Tacrolimus Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Blood lactate dehydrogenase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Blood magnesium decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Blood potassium increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Blood pressure decreased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Blood pressure increased 0.0 0.0 1.0 1.0 1.0 0.0 0.0 Tacrolimus Blood urea increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Blood uric acid increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Bone disorder 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Tacrolimus Bone marrow failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Bone pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Bradyphrenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Brain injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Brain oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Burning sensation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus C-reactive protein increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Cachexia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Candida infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Cardiac disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Cardiac failure acute 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Cardiac failure congestive 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Cardiomegaly 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Cardiovascular disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Cataract 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Cerebral haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Cerebral infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Cerebral ischaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Cerebrovascular accident 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Chest discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Chest pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Cholangitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Cholecystitis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Cholestasis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Chronic kidney disease 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Chronic obstructive pulmonary disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Clostridium difficile colitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Clostridium difficile infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Coagulopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Cognitive disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Colitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Colitis ulcerative 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Colon cancer 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Confusional state 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Congestive cardiomyopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Cough 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Crohn's disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tacrolimus Cystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Deep vein thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Dental caries 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tacrolimus Depressed level of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Depressed mood 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Dermatitis contact 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Diabetic ketoacidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Diarrhoea haemorrhagic 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Diplopia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Disease recurrence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tacrolimus Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Disseminated intravascular coagulation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Disturbance in attention 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Diverticulitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tacrolimus Dry mouth 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Dry skin 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Dyskinesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Dysmenorrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Dysphagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Dysphonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Dyspnoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Ear infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Ear pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Eczema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Electrocardiogram abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Electrolyte imbalance 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Encephalitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Encephalopathy 1.0 1.0 1.0 0.0 1.0 0.0 0.0 Tacrolimus Epilepsy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Erythema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Erythema multiforme 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tacrolimus Extrapyramidal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Eye pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Failure to thrive 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Fatigue 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Febrile neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Feeling abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Femur fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Flank pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Fluid overload 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Fluid retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Flushing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Foetal growth restriction 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Tacrolimus Fungal infection 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Fungal skin infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Gait disturbance 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Gamma-glutamyltransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Gastric cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Gastroenteritis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Gastroenteritis viral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Generalised oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Generalised tonic-clonic seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Haematemesis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Haematoma 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Haemoptysis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Haemorrhage 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Haemorrhage intracranial 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Hallucination, visual 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Hemiparesis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Hemiplegia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Hepatic cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Hepatic encephalopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Hepatic enzyme increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Hepatic function abnormal 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Hepatic necrosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Hepatitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Hepatitis cholestatic 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Hepatomegaly 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Hernia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Herpes simplex 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Herpes zoster 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Hip fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Hot flush 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tacrolimus Hydronephrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Hyperbilirubinaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Hypercalcaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Hyperglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Hyperkalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Hyperlipidaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Hypersensitivity vasculitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tacrolimus Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Hypertensive crisis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Hypertriglyceridaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Hyperuricaemia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Hypoaesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Hypoalbuminaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Hypoglycaemia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Hypomagnesaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Hypotension 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Hypothyroidism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Hypotonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Hypoxia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Ileus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Ill-defined disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Inappropriate antidiuretic hormone secretion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Increased appetite 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Tacrolimus Infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Interstitial lung disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Intestinal obstruction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Intestinal perforation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Intracranial pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Intraocular pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tacrolimus Iron deficiency anaemia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Irritability 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Tacrolimus Jaundice 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Laboratory test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Lactic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Large intestine perforation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Leukocytosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Liver disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Liver function test abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Localised infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Loss of consciousness 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Lower respiratory tract infection 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Lung disorder 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Lung infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Lung infiltration 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Lymphadenopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Lymphoma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Lymphopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Malignant melanoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Malnutrition 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Mass 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Melaena 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Tacrolimus Meningitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Mental disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Mental impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Mental status changes 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Metabolic acidosis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Metastases to central nervous system 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Metastases to liver 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Metastases to lung 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Micturition disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Migraine 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Mitral valve incompetence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Mobility decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Muscle spasms 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Tacrolimus Muscular weakness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Musculoskeletal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Musculoskeletal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Myalgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Myocardial ischaemia 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Myocarditis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Myositis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Nausea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Neck pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Necrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Nephrolithiasis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Nephropathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Nephropathy toxic 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Nervous system disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Nervousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tacrolimus Neuralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Neurological symptom 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Neurotoxicity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Night sweats 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Nystagmus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Obstructive airways disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Oedema 0.0 0.0 1.0 1.0 1.0 0.0 0.0 Tacrolimus Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Oesophagitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Oliguria 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Oropharyngeal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Osteoarthritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Osteomyelitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Osteonecrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Osteoporosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Pain of skin 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Pallor 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Pancreatic carcinoma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Pancreatitis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Pancreatitis acute 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Paralysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Parkinsonism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Pericardial effusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Pericarditis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Peritonitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Pharyngitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Phlebitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Photosensitivity reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tacrolimus Plasma cell myeloma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Platelet count decreased 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Tacrolimus Pleural effusion 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Pneumocystis jirovecii pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Pneumonia aspiration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Pneumonia bacterial 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Pneumonitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Pneumothorax 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Pollakiuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Polyp 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Polyuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Posterior reversible encephalopathy syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 1.0 Tacrolimus Premature delivery 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tacrolimus Productive cough 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Protein urine present 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Tacrolimus Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Psychotic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Pulmonary alveolar haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Pulmonary embolism 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Pulmonary fibrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Pulmonary haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Pulmonary oedema 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Pyelonephritis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Pyrexia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Rash 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Rash erythematous 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Rash maculo-papular 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Renal disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Renal impairment 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Renal tubular necrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Respiratory disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Respiratory distress 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Restlessness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tacrolimus Retinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Rheumatoid arthritis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Shock haemorrhagic 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Sinus tachycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Sinusitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Skin burning sensation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Skin cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tacrolimus Skin discolouration 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Skin exfoliation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Skin lesion 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Skin necrosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Skin ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Sleep apnoea syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Small intestinal obstruction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Somnolence 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Spinal compression fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Splenomegaly 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Tacrolimus Squamous cell carcinoma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Staphylococcal infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Status epilepticus 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Stomatitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Stress cardiomyopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Subarachnoid haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Swelling face 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Systemic lupus erythematosus 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Tacrolimus Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Tachypnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Thrombocytopenia 1.0 1.0 0.0 0.0 1.0 0.0 0.0 Tacrolimus Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Thrombotic thrombocytopenic purpura 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Tinnitus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Tooth disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Toothache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Torsade de pointes 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Toxic epidermal necrolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Transient ischaemic attack 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Tacrolimus Treatment failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Ulcer 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Upper respiratory tract infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Urethral disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Urinary incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Urine output decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Urosepsis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Urticaria 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Tacrolimus Vasculitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Venous thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Ventricular fibrillation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Ventricular tachycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Vertigo 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Visual acuity reduced 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tacrolimus Visual field defect 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tacrolimus Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus Weight decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tacrolimus White blood cell count decreased 0.0 0.0 1.0 1.0 1.0 0.0 0.0 Tacrolimus White blood cell count increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Acute coronary syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tadalafil Acute kidney injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tadalafil Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tadalafil Anxiety 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tadalafil Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Asthma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tadalafil Balance disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Basal cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tadalafil Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tadalafil Blood glucose decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Blood pressure abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tadalafil Cardiac disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Cardiac failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Cardiac failure acute 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Cardiac failure congestive 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tadalafil Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tadalafil Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Cerebral haemorrhage 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Cerebral infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Cerebrovascular accident 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Chronic obstructive pulmonary disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Constipation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tadalafil Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Cyanosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Deafness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Tadalafil Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tadalafil Decreased appetite 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Tadalafil Decubitus ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Disease progression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tadalafil Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tadalafil Dysgeusia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Dyskinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Dysphagia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tadalafil Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Dyspnoea exertional 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Emotional distress 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tadalafil Epistaxis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Erectile dysfunction 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Tadalafil Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tadalafil Eye disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tadalafil Eye haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tadalafil Eye swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tadalafil Fluid overload 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Fluid retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Gastrointestinal disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tadalafil Haematuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tadalafil Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Haemoptysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tadalafil Herpes zoster 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Hip fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Hot flush 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Hypoxia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Interstitial lung disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tadalafil Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Joint swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Localised infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Lung disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Lung infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tadalafil Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Malignant melanoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tadalafil Meningitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Menorrhagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tadalafil Musculoskeletal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tadalafil Nasopharyngitis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Tadalafil Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Neck pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tadalafil Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Oxygen saturation decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tadalafil Pain in extremity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tadalafil Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Pericardial effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Pharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Platelet count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tadalafil Pleural effusion 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Priapism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tadalafil Productive cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Prostate cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tadalafil Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tadalafil Pulmonary congestion 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tadalafil Pulmonary embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tadalafil Pulmonary hypertension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Renal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Renal failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tadalafil Respiratory disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tadalafil Respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Retinal detachment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tadalafil Sepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tadalafil Shock 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Squamous cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tadalafil Subarachnoid haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tadalafil Subdural haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Suicidal ideation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tadalafil Supraventricular tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Swelling face 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tadalafil Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tadalafil Torsade de pointes 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tadalafil Unevaluable event 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Upper respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Urinary tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Ventricular fibrillation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tadalafil Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Visual acuity reduced 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tadalafil Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tadalafil Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Weight decreased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tadalafil Weight increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tadalafil Wheezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tafamidis Abdominal distension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tafamidis Acute kidney injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tafamidis Atrial fibrillation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tafamidis Atrial flutter 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tafamidis Balance disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tafamidis Cardiac disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tafamidis Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tafamidis Cardiac failure congestive 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tafamidis Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tafamidis Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tafamidis Fluid retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tafamidis Hypoacusis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tafamidis Hypoaesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tafamidis Malaise 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tafamidis Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tafamidis Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tafamidis Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tafamidis Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tafamidis Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tafluprost Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Talazoparib Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Talazoparib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Talazoparib Neoplasm progression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Talazoparib Neutropenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Talazoparib Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tamoxifen Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tamoxifen Arthralgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tamoxifen Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tamoxifen Bone pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tamoxifen Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tamoxifen Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tamoxifen Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tamoxifen Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tamoxifen Hot flush 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Tamoxifen Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tamoxifen Influenza like illness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tamoxifen Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tamoxifen Malaise 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tamoxifen Malignant neoplasm progression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tamoxifen Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tamoxifen Musculoskeletal stiffness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tamoxifen Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tamoxifen Paraesthesia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tamoxifen Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tamoxifen Visual acuity reduced 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tamoxifen Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tamoxifen citrate Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tamoxifen citrate Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tamoxifen citrate Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tamoxifen citrate Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tamoxifen citrate Diarrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tamoxifen citrate Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tamoxifen citrate Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tamoxifen citrate Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tamoxifen citrate Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tamoxifen citrate Pelvic pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tamoxifen citrate Vaginal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tamoxifen citrate Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tamsulosin Abdominal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tamsulosin Abdominal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tamsulosin Abdominal pain lower 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tamsulosin Agitation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tamsulosin Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tamsulosin Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tamsulosin Arrhythmia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tamsulosin Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Tamsulosin Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tamsulosin Asthma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tamsulosin Atrial fibrillation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tamsulosin Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tamsulosin Balance disorder 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Tamsulosin Blood glucose increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tamsulosin Blood pressure decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tamsulosin Blood urine present 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tamsulosin Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tamsulosin Cataract 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Tamsulosin Chills 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tamsulosin Circulatory collapse 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tamsulosin Cognitive disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tamsulosin Confusional state 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tamsulosin Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tamsulosin Contusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tamsulosin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tamsulosin Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tamsulosin Diarrhoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tamsulosin Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tamsulosin Drug interaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tamsulosin Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tamsulosin Dysuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tamsulosin Erectile dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Tamsulosin Erythema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tamsulosin Eye swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tamsulosin Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Tamsulosin Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tamsulosin Gastrointestinal disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tamsulosin Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tamsulosin Hypertension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tamsulosin Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tamsulosin Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tamsulosin Interstitial lung disease 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Tamsulosin Libido decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tamsulosin Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tamsulosin Lung disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tamsulosin Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tamsulosin Memory impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tamsulosin Mental status changes 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tamsulosin Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tamsulosin Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tamsulosin Nasal congestion 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tamsulosin Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tamsulosin Neck pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tamsulosin Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tamsulosin Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tamsulosin Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tamsulosin Palpitations 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tamsulosin Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tamsulosin Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tamsulosin Pollakiuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tamsulosin Prostate cancer 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tamsulosin Prostatic disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tamsulosin Pulmonary embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tamsulosin Pyrexia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tamsulosin Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tamsulosin Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tamsulosin Skin disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tamsulosin Sleep disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tamsulosin Swelling face 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tamsulosin Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tamsulosin Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tamsulosin Urinary tract infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tamsulosin Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tamsulosin Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tamsulosin Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tamsulosin Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tamsulosin hydrochloride Atrial fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tamsulosin hydrochloride Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tamsulosin hydrochloride Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tamsulosin hydrochloride Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tamsulosin hydrochloride Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tamsulosin hydrochloride Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tamsulosin hydrochloride Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Tapentadol Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tapentadol Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tapentadol Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tapentadol Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tapentadol Delirium 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tapentadol Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tapentadol Dysphagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tapentadol Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tapentadol Hallucination 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tapentadol Hyperhidrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tapentadol Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tapentadol Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tapentadol Malaise 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tapentadol Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tapentadol Psychotic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tapentadol Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tapentadol Serotonin syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tapentadol Somnolence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tapentadol Tachycardia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tapentadol hydrochloride Agitation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tapentadol hydrochloride Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tapentadol hydrochloride Cardiac disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tapentadol hydrochloride Confusional state 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tapentadol hydrochloride Constipation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tapentadol hydrochloride Depressed level of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tapentadol hydrochloride Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tapentadol hydrochloride Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tapentadol hydrochloride Drug interaction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tapentadol hydrochloride Drug withdrawal syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tapentadol hydrochloride Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tapentadol hydrochloride Hallucination 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tapentadol hydrochloride Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tapentadol hydrochloride Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tapentadol hydrochloride Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tapentadol hydrochloride Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tapentadol hydrochloride Lethargy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tapentadol hydrochloride Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tapentadol hydrochloride Oxygen saturation decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tapentadol hydrochloride Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tapentadol hydrochloride Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tapentadol hydrochloride Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tapentadol hydrochloride Respiratory depression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tapentadol hydrochloride Somnolence 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tapentadol hydrochloride Suicidal ideation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tapentadol hydrochloride Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tapentadol hydrochloride Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tapentadol hydrochloride Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tapentadol hydrochloride Withdrawal syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tasimelteon Abnormal dreams 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tasimelteon Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tasimelteon Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tasimelteon Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tasimelteon Chronic obstructive pulmonary disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tasimelteon Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tasimelteon Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tasimelteon Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tasimelteon Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tasimelteon Diverticulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tasimelteon Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tasimelteon Fluid overload 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tasimelteon Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tasimelteon Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tasimelteon Insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tasimelteon Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tasimelteon Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tasimelteon Middle insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tasimelteon Nightmare 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tasimelteon Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tasimelteon Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Tasimelteon Poor quality sleep 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tasimelteon Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tasimelteon Suicidal ideation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tasimelteon Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tasimelteon Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tasimelteon Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tedizolid phosphate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tedizolid phosphate Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tedizolid phosphate Thrombocytopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teduglutide Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teduglutide Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teduglutide Cholecystitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teduglutide Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teduglutide Flatulence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teduglutide Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teduglutide Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teduglutide Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teduglutide Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teduglutide Sleep disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teduglutide Upper respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teduglutide Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telaprevir Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telaprevir Dermatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Telaprevir Dysgeusia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Telaprevir Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Telaprevir Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Telbivudine Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telbivudine Blood creatine phosphokinase increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Telbivudine Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telbivudine Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telbivudine Lactic acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telbivudine Myopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telbivudine Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telbivudine Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telbivudine Vomiting 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Telmisartan Abdominal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Telmisartan Abdominal distension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Telmisartan Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telmisartan Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Telmisartan Arthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Telmisartan Asthenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Telmisartan Atrioventricular block complete 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Telmisartan Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Telmisartan Balance disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Telmisartan Blood pressure increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Telmisartan Blood uric acid increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Telmisartan Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Telmisartan Cerebral haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telmisartan Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telmisartan Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telmisartan Coordination abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Telmisartan Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Telmisartan Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Telmisartan Delirium 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Telmisartan Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Telmisartan Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Telmisartan Dry mouth 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Telmisartan Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Telmisartan Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telmisartan Face oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telmisartan Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telmisartan Gastritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Telmisartan Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Telmisartan Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telmisartan Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Telmisartan Hyperkalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Telmisartan Hypernatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telmisartan Hypoaesthesia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Telmisartan Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telmisartan Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Telmisartan Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Telmisartan Interstitial lung disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Telmisartan Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telmisartan Joint swelling 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Telmisartan Lactic acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telmisartan Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Telmisartan Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telmisartan Metabolic acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Telmisartan Migraine 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Telmisartan Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Telmisartan Musculoskeletal stiffness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Telmisartan Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Telmisartan Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telmisartan Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telmisartan Peripheral swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Telmisartan Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Telmisartan Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Telmisartan Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Telmisartan Psoriasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Telmisartan Pulmonary embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Telmisartan Renal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telmisartan Renal failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telmisartan Renal impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telmisartan Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telmisartan Sciatica 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Telmisartan Sepsis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telmisartan Shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Telmisartan Somnolence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Telmisartan Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Telmisartan Swelling face 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telmisartan Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telmisartan Tremor 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Telmisartan Unevaluable event 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telmisartan Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Telmisartan Vertigo 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Telmisartan Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telotristat ethyl Abdominal discomfort 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Telotristat ethyl Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telotristat ethyl Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telotristat ethyl Blood alkaline phosphatase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Telotristat ethyl Blood magnesium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telotristat ethyl Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telotristat ethyl Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Telotristat ethyl Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telotristat ethyl Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telotristat ethyl Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Telotristat ethyl Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telotristat ethyl Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Telotristat ethyl Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telotristat ethyl Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telotristat ethyl Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telotristat ethyl Neoplasm progression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Telotristat ethyl Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Telotristat ethyl Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telotristat ethyl Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Telotristat ethyl Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telotristat ethyl Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telotristat ethyl Small intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Telotristat ethyl Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temazepam Aggression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Temazepam Amnesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Temazepam Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Temazepam Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temazepam Confusional state 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Temazepam Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temazepam Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temazepam Depressed level of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temazepam Diarrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Temazepam Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Temazepam Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temazepam Dysarthria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Temazepam Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temazepam Gait disturbance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Temazepam Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Temazepam Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temazepam Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Temazepam Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Temazepam Respiratory depression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temazepam Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Temazepam Thinking abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Temozolomide Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Abscess 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Acute hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Acute myeloid leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Acute respiratory failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Ageusia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Agranulocytosis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Alanine aminotransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Altered state of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Anaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Aphasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Aplastic anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Asthenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Ataxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Balance disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Blood albumin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Blood alkaline phosphatase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Blood bilirubin increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Blood count abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Blood lactate dehydrogenase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Blood pressure increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Bone marrow failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Brain oedema 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Temozolomide C-reactive protein increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Cerebrovascular accident 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Cholelithiasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Temozolomide Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Cognitive disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Contusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Deafness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Decreased appetite 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Deep vein thrombosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Diarrhoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Disease recurrence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Temozolomide Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Drug eruption 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Drug-induced liver injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Temozolomide Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Temozolomide Dysphagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Dyspnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Encephalopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Facial paralysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Febrile neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Gamma-glutamyltransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Generalised tonic-clonic seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Haemoptysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Headache 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Hemiparesis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Hepatic function abnormal 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Hepatotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Temozolomide Herpes zoster 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Hypoaesthesia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Hypokalaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Hyponatraemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Lethargy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Localised infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Lymphocyte count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Lymphopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Malaise 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Temozolomide Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Temozolomide Mental status changes 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Metastases to liver 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Mobility decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Mucosal inflammation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Muscle twitching 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Myelodysplastic syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Nausea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Neutrophil count decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Oesophagitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Temozolomide Oral candidiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Oxygen saturation decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Paraesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Petechiae 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Platelet count decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Pneumocystis jirovecii pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Pneumonia aspiration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Pollakiuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Productive cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Pulmonary embolism 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Pyrexia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Rash 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Seizure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Skin exfoliation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Speech disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Stevens-Johnson syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Swelling face 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Toxic epidermal necrolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Transaminases increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Temozolomide Treatment failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Temozolomide Tremor 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Unresponsive to stimuli 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Urinary incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Visual impairment 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temozolomide Weight decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Temozolomide Weight increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temozolomide White blood cell count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temozolomide White blood cell count increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Temsirolimus Anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temsirolimus Blood creatinine increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temsirolimus Cough 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temsirolimus Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temsirolimus Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temsirolimus Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temsirolimus Diarrhoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Temsirolimus Dyspnoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temsirolimus Febrile neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temsirolimus Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temsirolimus Hyperglycaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temsirolimus Insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temsirolimus Interstitial lung disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temsirolimus Nausea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temsirolimus Neutrophil count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temsirolimus Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temsirolimus Pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temsirolimus Pericardial effusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temsirolimus Platelet count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temsirolimus Pleural effusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temsirolimus Pneumocystis jirovecii pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temsirolimus Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Temsirolimus Pyrexia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temsirolimus Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temsirolimus Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Temsirolimus Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Temsirolimus Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Temsirolimus Stomatitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Temsirolimus Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Temsirolimus Vomiting 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Temsirolimus Weight decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tenofovir Acute kidney injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tenofovir Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tenofovir Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tenofovir Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tenofovir Glycosuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tenofovir Lactic acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tenofovir Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tenofovir Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tenofovir Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tenofovir Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tenofovir Renal tubular necrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tenofovir alafenamide Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tenofovir alafenamide Neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tenofovir disoproxil Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tenofovir disoproxil Chronic kidney disease 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tenofovir disoproxil Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tenofovir disoproxil Drug resistance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tenofovir disoproxil Foetal growth restriction 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Tenofovir disoproxil Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tenofovir disoproxil Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tenofovir disoproxil Osteoporosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tenofovir disoproxil Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Tenofovir disoproxil Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tenofovir disoproxil Rhabdomyolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tenofovir disoproxil Treatment failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tenofovir disoproxil fumarate Acute kidney injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tenofovir disoproxil fumarate Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tenofovir disoproxil fumarate Arthralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tenofovir disoproxil fumarate Back pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tenofovir disoproxil fumarate Bone pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tenofovir disoproxil fumarate Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tenofovir disoproxil fumarate Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tenofovir disoproxil fumarate Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tenofovir disoproxil fumarate Glycosuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tenofovir disoproxil fumarate Haematuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tenofovir disoproxil fumarate Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tenofovir disoproxil fumarate Hypophosphataemia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tenofovir disoproxil fumarate Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Tenofovir disoproxil fumarate Lactic acidosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tenofovir disoproxil fumarate Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tenofovir disoproxil fumarate Pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tenofovir disoproxil fumarate Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tenofovir disoproxil fumarate Proteinuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tenofovir disoproxil fumarate Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tenofovir disoproxil fumarate Renal failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Terbinafine Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Terbinafine Acute generalised exanthematous pustulosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Terbinafine Acute hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Terbinafine Acute kidney injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Terbinafine Ageusia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Terbinafine Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Terbinafine Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Terbinafine Aphthous ulcer 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Aplastic anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Terbinafine Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Blister 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Terbinafine Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Terbinafine Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Terbinafine Cheilitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Terbinafine Colitis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Terbinafine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Terbinafine Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Deep vein thrombosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Terbinafine Dementia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Depressed level of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Terbinafine Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Disorientation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Drug resistance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Terbinafine Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Dysgeusia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Dysphagia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Terbinafine Epilepsy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Terbinafine Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Terbinafine Erythema multiforme 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Face oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Terbinafine Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Flushing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Terbinafine Fungal skin infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Terbinafine Gastrointestinal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Gastrointestinal haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Terbinafine Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Heart rate increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Terbinafine Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Terbinafine Hepatocellular injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Terbinafine Hypertension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Terbinafine Ileus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Terbinafine Influenza like illness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Lethargy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Limb discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Lip swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Terbinafine Liver function test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Terbinafine Lymphadenopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Terbinafine Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Migraine 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Terbinafine Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Terbinafine Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Musculoskeletal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Terbinafine Musculoskeletal stiffness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Neutropenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Terbinafine Nightmare 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Terbinafine Oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Terbinafine Oral discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Oropharyngeal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Pain in extremity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Terbinafine Pancytopenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Photosensitivity reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Terbinafine Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Terbinafine Pruritus generalised 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Terbinafine Psoriasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Terbinafine Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Terbinafine Rash 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Terbinafine Rash erythematous 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Rash generalised 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Terbinafine Rash papular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Terbinafine Rash pruritic 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Rash pustular 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Terbinafine Renal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Restlessness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Rhabdomyolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Terbinafine Salivary hypersecretion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Terbinafine Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Terbinafine Shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Terbinafine Sinus bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Terbinafine Skin exfoliation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Skin reaction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Terbinafine Sleep disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Stomatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Terbinafine Suicidal ideation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Terbinafine Swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Swollen tongue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Terbinafine Syncope 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Terbinafine Systemic lupus erythematosus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Terbinafine Throat tightness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Terbinafine Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Terbinafine Thrombophlebitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Terbinafine Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Toxic epidermal necrolysis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Treatment failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Terbinafine Tremor 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Terbinafine Urinary retention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Terbinafine Vertigo 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Vomiting 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine Weight decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine White blood cell count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Terbinafine hydrochloride Acute generalised exanthematous pustulosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Terbinafine hydrochloride Ageusia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine hydrochloride Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Terbinafine hydrochloride Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine hydrochloride Arthralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Terbinafine hydrochloride Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Terbinafine hydrochloride Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine hydrochloride Dysgeusia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine hydrochloride Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine hydrochloride Hepatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Terbinafine hydrochloride Hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine hydrochloride Malaise 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Terbinafine hydrochloride Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine hydrochloride Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine hydrochloride Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Terbinafine hydrochloride Rash 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Terbinafine hydrochloride Rhabdomyolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Terbinafine hydrochloride Weight decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Abasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Abdominal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Abdominal pain 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Teriflunomide Abdominal pain upper 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teriflunomide Abscess 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Acne 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Acute coronary syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Acute hepatic failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Acute myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Teriflunomide Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Teriflunomide Acute respiratory failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Ageusia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Aggression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teriflunomide Agitation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Alanine aminotransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teriflunomide Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Amenorrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teriflunomide Amnesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Amylase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Anaemia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Anal incontinence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Aphasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Appetite disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teriflunomide Arrhythmia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Arthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Arthropathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Ascites 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Aspiration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Asthma 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Ataxia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Bacterial infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Balance disorder 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Basal cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teriflunomide Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Blister 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Blood cholesterol increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Blood creatinine increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Blood glucose increased 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Teriflunomide Blood lactate dehydrogenase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Blood potassium decreased 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Teriflunomide Blood pressure decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Blood pressure increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Blood urine present 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Bone pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Breast cancer 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Teriflunomide Bronchitis 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Teriflunomide Burning sensation 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Teriflunomide Cardiac disorder 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Teriflunomide Cardiac failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Teriflunomide Cardiovascular disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Carpal tunnel syndrome 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Cerebral haemorrhage 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Cerebrovascular accident 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Chest discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Chest pain 0.0 0.0 1.0 1.0 1.0 0.0 0.0 Teriflunomide Chills 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Cholecystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Chromaturia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Clostridium difficile colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Clostridium difficile infection 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Teriflunomide Cognitive disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Colitis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Teriflunomide Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Teriflunomide Confusional state 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Contusion 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Coordination abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Coronary artery disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Cough 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Crohn's disease 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Crying 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Cyst 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Cystitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Deafness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Teriflunomide Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Decubitus ulcer 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Teriflunomide Deep vein thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Teriflunomide Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Depressed mood 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Depression 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Dermatitis contact 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Diabetes mellitus 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Diplopia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Disorientation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Drug hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teriflunomide Drug-induced liver injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Dry eye 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Dry skin 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Dysarthria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Dysgeusia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Dyskinesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teriflunomide Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Dysphagia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Dysphonia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Dyspnoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Dysstasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Dysuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Ear infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Emotional disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Epistaxis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teriflunomide Erythema 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Eye disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Eye pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Facial paralysis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Faeces discoloured 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Feeling cold 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Feeling hot 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Flatulence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Flushing 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Frequent bowel movements 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Fungal infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Gastric disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Gastric haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Gastritis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Teriflunomide Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Gastroenteritis viral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Gastrointestinal disorder 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Gastrooesophageal reflux disease 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Glaucoma 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Haematochezia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Haematoma 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Haemoglobin decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Hallucination 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Headache 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Hemiparesis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Hepatic enzyme increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Teriflunomide Herpes zoster 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Hip fracture 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Teriflunomide Hot flush 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Hyperhidrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Hypersomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Hypertension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Hyperthyroidism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teriflunomide Hypoacusis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Hypoaesthesia oral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teriflunomide Hypokinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Hypoxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Teriflunomide Ill-defined disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Immune system disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Incontinence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Infection 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Teriflunomide Inflammation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Influenza 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Influenza like illness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Intervertebral disc protrusion 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Irritable bowel syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Joint swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Lacrimation increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Laryngitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Lethargy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Leukopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teriflunomide Limb discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Liver disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Liver function test abnormal 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Teriflunomide Local swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teriflunomide Loss of consciousness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Lower respiratory tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teriflunomide Lung disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Lymphoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teriflunomide Lymphopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teriflunomide Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Malignant melanoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teriflunomide Malnutrition 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Mass 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Mental disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Mental impairment 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Micturition urgency 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Mobility decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Mood altered 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Mood swings 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Motor dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Movement disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Muscle twitching 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Musculoskeletal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Musculoskeletal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Musculoskeletal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Musculoskeletal stiffness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Myocardial infarction 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Teriflunomide Nail disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teriflunomide Nasal congestion 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Nasopharyngitis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Nausea 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Neck pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Neoplasm 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Neoplasm malignant 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Nervous system disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Nervousness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Neuralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Neutropenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teriflunomide Neutrophil count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teriflunomide Night sweats 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teriflunomide Oedema peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Optic neuritis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Oropharyngeal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Osteoarthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Pain in jaw 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Pain of skin 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Palpitations 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Pancreatitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Peripheral coldness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Peritonitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Petechiae 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Pharyngitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teriflunomide Photosensitivity reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teriflunomide Platelet count decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Pneumonia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Teriflunomide Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Teriflunomide Pollakiuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Polyneuropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teriflunomide Poor quality sleep 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Productive cough 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Pulmonary embolism 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Pyrexia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Teriflunomide Rash 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Rash macular 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Rash papular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teriflunomide Rash pruritic 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Raynaud's phenomenon 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teriflunomide Rectal haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teriflunomide Red blood cell count decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Renal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Respiratory disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Teriflunomide Respiratory tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teriflunomide Restless legs syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Restlessness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Rheumatoid arthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teriflunomide Rhinorrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Sciatica 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Seizure 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Sensory disturbance 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Sensory loss 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Sepsis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Teriflunomide Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Teriflunomide Sinus disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Sinusitis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Skin cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teriflunomide Skin discolouration 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Skin lesion 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Skin mass 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Skin ulcer 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Sleep disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Sluggishness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Sneezing 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Somnolence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Speech disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Staphylococcal infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Status epilepticus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Stomatitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Stress 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Subarachnoid haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Teriflunomide Swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Tachycardia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Tendonitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Thinking abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Throat irritation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Thrombosis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Teriflunomide Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Tooth abscess 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teriflunomide Toothache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Transient ischaemic attack 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriflunomide Unevaluable event 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Teriflunomide Upper respiratory tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teriflunomide Urinary incontinence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Urinary retention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Urinary tract infection 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Teriflunomide Vaginal infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teriflunomide Vertigo 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Viral infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Visual acuity reduced 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Visual field defect 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Teriflunomide Vomiting 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Teriflunomide Weight decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriflunomide White blood cell count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teriflunomide White blood cell count increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Teriparatide Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriparatide Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriparatide Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriparatide Bone disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teriparatide Cardiac disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriparatide Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriparatide Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriparatide Contusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriparatide Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriparatide Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Teriparatide Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriparatide Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriparatide Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriparatide Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriparatide Haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriparatide Hypercalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriparatide Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriparatide Loss of consciousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Teriparatide Malnutrition 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriparatide Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriparatide Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriparatide Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriparatide Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriparatide Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriparatide Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Teriparatide Swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriparatide Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriparatide Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Teriparatide Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tesamorelin Depression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone Abdominal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Abdominal pain upper 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Testosterone Acne 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Testosterone Acute coronary syndrome 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Testosterone Acute kidney injury 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Testosterone Acute myocardial infarction 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone Acute pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone Acute respiratory failure 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Testosterone Aggression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Amnesia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone Anaemia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone Anger 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Angina pectoris 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone Angiopathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Anxiety 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone Aphasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone Arrhythmia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Testosterone Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Arthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Arthropathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Asthenia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone Asthma 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Atelectasis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone Atrial fibrillation 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone Atrial flutter 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Balance disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Blood cholesterol increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone Bradycardia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Testosterone Bradyphrenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone Brain injury 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Testosterone Brain oedema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Testosterone Bronchitis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone Cardiac arrest 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Testosterone Cardiac disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Cardiac failure 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Testosterone Cardiac failure acute 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Testosterone Cardiac failure congestive 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Testosterone Cardiogenic shock 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Testosterone Cardiomegaly 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Testosterone Cardiomyopathy 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Testosterone Cardiopulmonary failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Testosterone Cardiotoxicity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Testosterone Cardiovascular disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Testosterone Cellulitis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone Cerebral haemorrhage 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Cerebral infarction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Cerebrovascular accident 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Cerebrovascular disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Testosterone Chest discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Chest pain 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone Chronic obstructive pulmonary disease 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Cognitive disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Testosterone Coma 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Testosterone Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Testosterone Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone Congestive cardiomyopathy 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Testosterone Coronary artery disease 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Testosterone Deep vein thrombosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone Depressed mood 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Testosterone Depression 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone Diabetes mellitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Dizziness 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone Drug abuse 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Testosterone Drug-induced liver injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone Dysphagia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Testosterone Dyspnoea 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone Ejection fraction decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone Embolism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Testosterone Embolism venous 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Emotional disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Emotional distress 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Testosterone Epistaxis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone Erectile dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Fatigue 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone Fear 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Gastrointestinal haemorrhage 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone Gout 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Haematoma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Testosterone Haematuria 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone Haemorrhage 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Haemorrhage intracranial 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone Haemorrhagic stroke 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Headache 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone Heart rate increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Testosterone Heart rate irregular 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone Hemiparesis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Hemiplegia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Hepatic function abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Testosterone Hernia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Hot flush 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Testosterone Hyperbilirubinaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone Hyperkalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone Hyperlipidaemia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Testosterone Hypertension 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone Hypertensive crisis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Hyperthyroidism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Testosterone Hypoaesthesia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone Hypokalaemia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Hypokinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone Hyponatraemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Testosterone Hypotension 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Testosterone Hypoxia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Testosterone Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone Influenza like illness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone Injection site pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone Insomnia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Testosterone Irritability 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Testosterone Ischaemia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Ischaemic stroke 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Joint swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Left ventricular dysfunction 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Testosterone Leukocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone Loss of consciousness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Lung disorder 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone Memory impairment 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone Mental disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Testosterone Mental status changes 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Mitral valve incompetence 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Testosterone Mobility decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Mood swings 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Testosterone Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Musculoskeletal chest pain 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone Myocardial infarction 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Testosterone Myocardial ischaemia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Nephrolithiasis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Testosterone Nervous system disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Oedema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Osteonecrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Testosterone Pain 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone Palpitations 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Testosterone Pancreatitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Pericarditis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Peripheral ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Peripheral vascular disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Pleural effusion 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Testosterone Pleurisy 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone Pneumonia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Testosterone Pneumonia aspiration 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Testosterone Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone Prostate cancer 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Pulmonary embolism 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Pulmonary hypertension 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone Pulmonary mass 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Pulmonary oedema 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Testosterone Renal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Renal failure 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Testosterone Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Testosterone Respiratory distress 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Testosterone Respiratory failure 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Testosterone Rhabdomyolysis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone Seizure 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Sepsis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Testosterone Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Testosterone Sinus tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Testosterone Sleep apnoea syndrome 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone Speech disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone Staphylococcal infection 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone Stress 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Subarachnoid haemorrhage 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Testosterone Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Testosterone Syncope 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone Tachycardia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Tendon rupture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone Thrombocytopenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Thrombophlebitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Thrombosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Transient ischaemic attack 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Unevaluable event 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Upper respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone Urinary tract infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Venous thrombosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Ventricular fibrillation 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Testosterone Ventricular tachycardia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Testosterone Vertigo 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Vomiting 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Weight decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone Wheezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone cypionate Acute myocardial infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone cypionate Amnesia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone cypionate Angina pectoris 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone cypionate Anxiety 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone cypionate Asthenia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone cypionate Atrial fibrillation 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone cypionate Balance disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone cypionate Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone cypionate Brain injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone cypionate Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Testosterone cypionate Cardiac disorder 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone cypionate Cardiac failure congestive 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone cypionate Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Testosterone cypionate Cardiovascular disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone cypionate Cerebrovascular accident 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone cypionate Chest pain 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone cypionate Coronary artery disease 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone cypionate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Testosterone cypionate Deep vein thrombosis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone cypionate Depression 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone cypionate Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone cypionate Dyspnoea 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone cypionate Fatigue 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone cypionate Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone cypionate Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone cypionate Heart rate irregular 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone cypionate Hemiparesis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone cypionate Hypertension 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone cypionate Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone cypionate Injection site pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Testosterone cypionate Ischaemic stroke 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone cypionate Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone cypionate Mobility decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone cypionate Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone cypionate Myocardial infarction 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone cypionate Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone cypionate Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone cypionate Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone cypionate Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone cypionate Pulmonary embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone cypionate Speech disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone cypionate Transient ischaemic attack 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone cypionate Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone enanthate Anxiety 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone enanthate Cerebrovascular accident 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Testosterone enanthate Depression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone enanthate Hypertension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone enanthate Myocardial infarction 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone undecanoate Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Testosterone undecanoate Blood pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Testosterone undecanoate Chest discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Testosterone undecanoate Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Testosterone undecanoate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Testosterone undecanoate Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone undecanoate Dyspnoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Testosterone undecanoate Erythema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Testosterone undecanoate Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Testosterone undecanoate Hyperhidrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Testosterone undecanoate Myocardial infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Testosterone undecanoate Paraesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tetrabenazine Abdominal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tetrabenazine Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tetrabenazine Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tetrabenazine Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tetrabenazine Aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tetrabenazine Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tetrabenazine Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tetrabenazine Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tetrabenazine Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tetrabenazine Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tetrabenazine Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tetrabenazine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tetrabenazine Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tetrabenazine Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tetrabenazine Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tetrabenazine Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tetrabenazine Dyskinesia 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Tetrabenazine Dysphagia 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Tetrabenazine Haematemesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tetrabenazine Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tetrabenazine Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tetrabenazine Hip fracture 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tetrabenazine Hypotension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Tetrabenazine Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tetrabenazine Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tetrabenazine Insomnia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tetrabenazine Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tetrabenazine Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tetrabenazine Movement disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tetrabenazine Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tetrabenazine Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tetrabenazine Neuroleptic malignant syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tetrabenazine Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Tetrabenazine Pneumonia aspiration 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Tetrabenazine Pyrexia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tetrabenazine Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tetrabenazine Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tetrabenazine Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tetrabenazine Sleep disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tetrabenazine Somnolence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tetrabenazine Suicidal ideation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tetrabenazine Suicide attempt 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tetrabenazine Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tetrabenazine Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tetrabenazine Unevaluable event 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tetrabenazine Unresponsive to stimuli 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tetrabenazine Urinary tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Tetrabenazine Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tetrabenazine Weight decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tetracycline hydrochloride Anaphylactic reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Thalidomide Abdominal discomfort 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Thalidomide Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Abdominal pain upper 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Acute kidney injury 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Acute myeloid leukaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Acute myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Acute respiratory distress syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Alanine aminotransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Arthropathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Ascites 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Asthenia 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Thalidomide Atrial fibrillation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Back pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Bacterial infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Basal cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Thalidomide Blood count abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Blood creatinine increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Blood potassium increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Bone pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Thalidomide Bradycardia 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Thalidomide Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Thalidomide Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Cardiac disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Cardiac failure congestive 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Cardiopulmonary failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Cardiovascular disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Thalidomide Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Cerebrovascular accident 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Chronic kidney disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Chronic obstructive pulmonary disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Clostridium difficile infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Congestive cardiomyopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Constipation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Cough 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Crohn's disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Thalidomide Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Decubitus ulcer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Deep vein thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Thalidomide Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Thalidomide Diarrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Diverticulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Thalidomide Drug hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Thalidomide Drug reaction with eosinophilia and systemic symptoms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Dry skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Thalidomide Dysphagia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Epistaxis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Facial paralysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Fatigue 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Thalidomide Febrile neutropenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Feeling abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Thalidomide Fluid overload 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Full blood count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Gastrointestinal disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Gout 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Haematochezia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Haematocrit decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Thalidomide Hepatic cirrhosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Herpes zoster 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Hip fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Hypercalcaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Hyperglycaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Hyperkalaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Thalidomide Hypertension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Hypoacusis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Thalidomide Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Thalidomide Hypotension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Hypoxia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Ileus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Thalidomide Intestinal perforation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Joint swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Thalidomide Leukopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Localised infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Lower respiratory tract infection 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Lung disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Lymphopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Malnutrition 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Muscular weakness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Thalidomide Myelodysplastic syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Nausea 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Thalidomide Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Nervous system disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Thalidomide Neutropenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Neutrophil count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Thalidomide Oedema peripheral 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Pancytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Pericardial effusion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Peripheral sensory neuropathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Plasma cell myeloma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Platelet count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Pleural effusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Pneumonia aspiration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Pneumonia bacterial 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Polyneuropathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Thalidomide Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Prostate cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Thalidomide Pulmonary embolism 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Pulmonary fibrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Pulmonary hypertension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Thalidomide Pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Pyrexia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Rash 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Respiratory distress 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Sepsis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Sinus bradycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Somnolence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Splenomegaly 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Tachycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Thrombocytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Thalidomide Unevaluable event 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Thalidomide Upper limb fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Urosepsis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thalidomide Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Thalidomide Venous thrombosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thalidomide Vomiting 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Thalidomide Wheezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Thiotepa Alopecia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thiotepa Anaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Thiotepa Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thiotepa Diarrhoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Thiotepa Febrile neutropenia 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Thiotepa Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thiotepa Leukopenia 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Thiotepa Mucosal inflammation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Thiotepa Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thiotepa Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thiotepa Pyrexia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Thiotepa Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thiotepa Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thiotepa Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Thiotepa Stomatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Thiotepa Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Thiotepa Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Thiothixene Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Thiothixene Parkinsonism 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ticagrelor Abdominal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Acute coronary syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Acute myocardial infarction 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Acute pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Acute respiratory distress syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Ageusia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Anaphylactic shock 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Anger 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Angina pectoris 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Angiopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ticagrelor Aphasia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ticagrelor Arrhythmia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Asphyxia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ticagrelor Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Asthma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Atrial fibrillation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Atrioventricular block complete 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Atrioventricular block second degree 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Back pain 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Ticagrelor Balance disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Blood glucose increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Blood pressure decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Brain oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Cardiac disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Cardiac failure congestive 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Cardiac tamponade 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Cardiogenic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Cardiovascular disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Cerebral haemorrhage 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Ticagrelor Cerebral infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Cerebrovascular accident 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Ticagrelor Chest discomfort 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Cholecystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Cholecystitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Chronic kidney disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Chronic obstructive pulmonary disease 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Circulatory collapse 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Confusional state 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ticagrelor Contusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Coronary artery disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Diabetes mellitus 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Disseminated intravascular coagulation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Diverticulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Duodenal ulcer 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Dyspepsia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Dyspnoea 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Ticagrelor Dyspnoea exertional 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Ear disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Ejection fraction decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Epistaxis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Eye disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Faeces discoloured 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Fatigue 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Feeling abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Flushing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Gait disturbance 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ticagrelor Gastric cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Gastric haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Gastric ulcer 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Gastrointestinal haemorrhage 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Gastrooesophageal reflux disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Haematemesis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Haematochezia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Haematocrit decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Haematuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Haemodynamic instability 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Haemoglobin decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Haemoptysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Haemorrhage intracranial 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Haemorrhagic stroke 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Ticagrelor Haemorrhoids 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Hemiparesis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Ticagrelor Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Hypertension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Hyperuricaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Hypoaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Immune thrombocytopenic purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ticagrelor Intracranial pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Iron deficiency anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Ischaemic stroke 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Ticagrelor Laceration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Liver function test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Loss of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Lung disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Lung infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Malaise 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Melaena 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Mitral valve incompetence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Myocardial infarction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Myocardial ischaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Nausea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ticagrelor Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Paraesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Pericardial effusion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Petechiae 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Platelet count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Presyncope 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Pruritus generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Pulmonary alveolar haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Pulmonary embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Pulmonary haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Pulmonary oedema 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Rales 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Rectal haemorrhage 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Renal impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Rhabdomyolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Shock haemorrhagic 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Sleep apnoea syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ticagrelor Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Subarachnoid haemorrhage 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Ticagrelor Subdural haematoma 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Ticagrelor Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Swollen tongue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Syncope 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Thrombocytopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Transient ischaemic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Troponin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Unevaluable event 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Unresponsive to stimuli 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Upper gastrointestinal haemorrhage 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Vasculitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Ventricular fibrillation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ticagrelor Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Visual impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ticagrelor Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticlopidine Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticlopidine Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticlopidine Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ticlopidine Pancytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tigecycline Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tigecycline Acute kidney injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tigecycline Blood alkaline phosphatase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tigecycline Blood bilirubin increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tigecycline Coagulopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tigecycline Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tigecycline Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tigecycline Drug resistance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tigecycline Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tigecycline Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tigecycline Hepatitis cholestatic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tigecycline Hepatotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tigecycline Liver injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tigecycline Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tigecycline Pancreatitis acute 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tigecycline Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tigecycline Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tigecycline Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tigecycline Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tigecycline Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tigecycline Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tigecycline Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tigecycline Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tigecycline Treatment failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tigecycline White blood cell count increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Timolol Asthma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Timolol Atrioventricular block 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Timolol Atrioventricular block complete 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Timolol Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Timolol Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Timolol Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Timolol Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Timolol Eye irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Timolol Eye pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Timolol Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Timolol Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Timolol Hypothermia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Timolol Intraocular pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Timolol Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Timolol Ocular hyperaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Timolol Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Timolol Vision blurred 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Timolol Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Timolol maleate Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Timolol maleate Bronchospasm 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Timolol maleate Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Timolol maleate Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Timolol maleate Eye irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Timolol maleate Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tiopronin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tiotropium Chronic obstructive pulmonary disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide Arrhythmia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide Renal failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Arthritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Candida infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Cataract 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Depression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Dry mouth 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Dysphagia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Dysphonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Epistaxis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Gastrooesophageal reflux disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Glossitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Herpes zoster 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Intestinal obstruction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Joint swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Laryngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Oral candidiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Sinusitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Skin ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Throat irritation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Upper respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tiotropium bromide monohydrate Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tipranavir Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tipranavir Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tipranavir Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tirofiban hydrochloride Haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tirofiban hydrochloride Haemorrhage intracranial 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tirofiban hydrochloride Myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tirofiban hydrochloride Thrombocytopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tizanidine Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tizanidine Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tizanidine Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tizanidine Atrioventricular block complete 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tizanidine Bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tizanidine Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tizanidine Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tizanidine Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tizanidine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tizanidine Discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tizanidine Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tizanidine Drug withdrawal syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tizanidine Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tizanidine Electrocardiogram QT prolonged 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tizanidine Hallucination, visual 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tizanidine Hyperglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tizanidine Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tizanidine Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tizanidine Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tizanidine Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tizanidine Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tizanidine Shock 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tizanidine Sinus bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tizanidine Sinus tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tizanidine Suicide attempt 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tizanidine Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tizanidine Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tizanidine hydrochloride Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tizanidine hydrochloride Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tizanidine hydrochloride Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tizanidine hydrochloride Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tizanidine hydrochloride Hallucination 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tizanidine hydrochloride Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tizanidine hydrochloride Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tizanidine hydrochloride Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Acute kidney injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tobramycin Acute respiratory failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Aspartate aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Asthma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Blood alkaline phosphatase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Blood glucose increased 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Tobramycin Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Cerebrovascular accident 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Chronic obstructive pulmonary disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Deafness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tobramycin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tobramycin Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Depression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Diarrhoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Disease progression 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tobramycin Dysphonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Haemoptysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Hip fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Hyperhidrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tobramycin Hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tobramycin Hypoxia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Tobramycin Ill-defined disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Leukocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Liver disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Lower respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Lung disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Lung infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Musculoskeletal chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Nephropathy toxic 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tobramycin Obstructive airways disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Oropharyngeal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Oxygen saturation decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Pneumothorax 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Productive cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Pulmonary congestion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Pulmonary embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Pulmonary function test decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Rales 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Rash 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Tobramycin Renal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Renal failure 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Tobramycin Respiratory disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Respiratory distress 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tobramycin Respiratory tract congestion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tobramycin Sinusitis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Tobramycin Speech disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Staphylococcal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tobramycin Unevaluable event 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tobramycin Wheezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tofacitinib Pulmonary embolism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tofacitinib citrate Abdominal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tofacitinib citrate Alanine aminotransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tofacitinib citrate Anaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tofacitinib citrate Arthralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tofacitinib citrate Breast cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tofacitinib citrate Cellulitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tofacitinib citrate Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tofacitinib citrate Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tofacitinib citrate Diarrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tofacitinib citrate Diverticulitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tofacitinib citrate Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tofacitinib citrate Dyspnoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tofacitinib citrate Erythema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tofacitinib citrate Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tofacitinib citrate Gastric cancer 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tofacitinib citrate Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tofacitinib citrate Hepatic enzyme increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tofacitinib citrate Hepatic steatosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tofacitinib citrate Herpes zoster 0.0 0.0 1.0 0.0 0.0 0.0 1.0 Tofacitinib citrate Hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tofacitinib citrate Infection 0.0 0.0 1.0 0.0 0.0 0.0 1.0 Tofacitinib citrate Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tofacitinib citrate Joint swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tofacitinib citrate Lung neoplasm malignant 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tofacitinib citrate Lymphocyte count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tofacitinib citrate Lymphoma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tofacitinib citrate Malignant melanoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tofacitinib citrate Musculoskeletal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tofacitinib citrate Nasopharyngitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tofacitinib citrate Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tofacitinib citrate Neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tofacitinib citrate Paraesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tofacitinib citrate Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tofacitinib citrate Prostate cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tofacitinib citrate Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tofacitinib citrate Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tofacitinib citrate Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tofacitinib citrate Sinus congestion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tofacitinib citrate Skin cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tofacitinib citrate Tendonitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tofacitinib citrate Upper respiratory tract infection 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tofacitinib citrate Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 1.0 Tofacitinib citrate Vomiting 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tolterodine Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tolterodine Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tolterodine tartrate Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tolterodine tartrate Dementia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tolterodine tartrate Feeling abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tolterodine tartrate Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tolvaptan Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tolvaptan Abdominal pain upper 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Acute hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Acute kidney injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Alanine aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Tolvaptan Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tolvaptan Altered state of consciousness 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Tolvaptan Anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tolvaptan Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Aspartate aminotransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tolvaptan Back pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Blood creatine phosphokinase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tolvaptan Blood creatinine increased 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Tolvaptan Blood glucose increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tolvaptan Blood pressure decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Blood pressure fluctuation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tolvaptan Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tolvaptan Blood urea increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tolvaptan Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Cardiac failure congestive 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tolvaptan Cerebral haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tolvaptan Cerebral infarction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tolvaptan Chronic kidney disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Chronic obstructive pulmonary disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tolvaptan Circulatory collapse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tolvaptan Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tolvaptan Dehydration 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Depressed level of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Depressed mood 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tolvaptan Depression 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tolvaptan Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Disseminated intravascular coagulation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tolvaptan Drug-induced liver injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tolvaptan Dry mouth 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tolvaptan Dysphagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Dyspnoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Erythema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tolvaptan Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tolvaptan Gamma-glutamyltransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tolvaptan Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tolvaptan Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tolvaptan Hepatic cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Hepatic cirrhosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Hepatic encephalopathy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Hepatic enzyme increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Hepatic function abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tolvaptan Hepatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tolvaptan Hepatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tolvaptan Hepatotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tolvaptan Hyperkalaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Hypernatraemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Hyperuricaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tolvaptan Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tolvaptan Hypoxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Ill-defined disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tolvaptan Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tolvaptan Interstitial lung disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tolvaptan Lethargy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Liver disorder 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Tolvaptan Liver function test abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tolvaptan Liver function test increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Liver injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tolvaptan Neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tolvaptan Nocturia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Tolvaptan Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tolvaptan Platelet count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Pleural effusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Pollakiuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Polyuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Pulmonary embolism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Pyrexia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Tolvaptan Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tolvaptan Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Renal impairment 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Tolvaptan Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Subarachnoid haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Thirst 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Transaminases increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Tremor 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tolvaptan Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tolvaptan Urine output increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tolvaptan Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tolvaptan Ventricular fibrillation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tolvaptan Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tolvaptan Weight decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Abdominal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Abdominal distension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Abdominal pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Topiramate Abdominal pain upper 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Acidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Topiramate Acne 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Acute hepatic failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Topiramate Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Topiramate Affect lability 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Ageusia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Agranulocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Topiramate Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Topiramate Amenorrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Amnesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Anal incontinence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Anaphylactic reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Anger 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Anxiety 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Topiramate Apathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Aphasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Arrhythmia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Arthropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Asthma 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Ataxia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Atrial septal defect 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Topiramate Balance disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Blood alkaline phosphatase increased 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Topiramate Blood creatine phosphokinase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Topiramate Bone pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Bradycardia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Bradyphrenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Brain injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Topiramate Cardiac disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Cataract 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Topiramate Chest pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Chills 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Cholestasis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Chromaturia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Coagulopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Topiramate Cognitive disorder 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Topiramate Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Topiramate Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Topiramate Confusional state 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Conjunctival hyperaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Cough 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Crying 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Topiramate Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Topiramate Decreased appetite 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Topiramate Dehydration 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Topiramate Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Topiramate Delusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Topiramate Dementia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Dental caries 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Depressed level of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Topiramate Depressed mood 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Topiramate Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Topiramate Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Topiramate Disturbance in attention 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Topiramate Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Topiramate Drug hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Topiramate Drug interaction 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Topiramate Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Drug reaction with eosinophilia and systemic symptoms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Topiramate Drug resistance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Drug withdrawal syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Topiramate Dry eye 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Dry skin 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Topiramate Dysarthria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Dysgeusia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Topiramate Dysphonia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Dyspnoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Dystonia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Dysuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Eating disorder 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Topiramate Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Topiramate Electrocardiogram abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Topiramate Emotional distress 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Encephalopathy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Topiramate Epilepsy 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Topiramate Epistaxis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Topiramate Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Erythema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Eye disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Eye irritation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Eye pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Topiramate Eye swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Failure to thrive 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Topiramate Fatigue 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Topiramate Fear 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Feeding disorder 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Topiramate Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Feeling cold 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Feeling hot 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Flatulence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Topiramate Foetal growth restriction 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Topiramate Gamma-glutamyltransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Topiramate Gastrooesophageal reflux disease 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Topiramate Gingival bleeding 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Topiramate Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Hallucination, visual 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Headache 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Topiramate Heart rate increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Heart rate irregular 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Hemiparesis 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Topiramate Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Topiramate Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Topiramate Hepatotoxicity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Hot flush 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Hydronephrosis 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Topiramate Hyperhidrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Hypernatraemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Topiramate Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Topiramate Hypersomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Hypertension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Hyperthermia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Topiramate Hypertonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Topiramate Hyperventilation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Topiramate Hypoacusis 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Topiramate Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Topiramate Hypoaesthesia oral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Hypocalcaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Topiramate Hypokalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Topiramate Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Topiramate Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Topiramate Hypothermia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Topiramate Hypothyroidism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Topiramate Hypotonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Topiramate Immune system disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Topiramate Influenza like illness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Insomnia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Topiramate Intentional self-injury 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Topiramate Intraocular pressure increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Irritability 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Joint swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Leukocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Topiramate Libido decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Limb discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Lip swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Liver function test abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Liver function test increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Liver injury 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Loss of consciousness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Topiramate Loss of libido 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Lymphopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Topiramate Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Mania 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Topiramate Maternal drugs affecting foetus 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Topiramate Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Mental disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Topiramate Mental impairment 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Topiramate Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Topiramate Metabolic acidosis 0.0 1.0 1.0 0.0 1.0 0.0 0.0 Topiramate Middle insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Migraine 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Topiramate Mobility decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Mood altered 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Topiramate Mood swings 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Topiramate Motor dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Mouth ulceration 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Muscle spasms 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Musculoskeletal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Musculoskeletal stiffness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Topiramate Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Nasal congestion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Nausea 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Topiramate Neck pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Nephrolithiasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Nervous system disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Nervousness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Neuralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Nightmare 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Oral disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Otitis media 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Topiramate Pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Topiramate Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Palpitations 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Topiramate Panic attack 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Topiramate Paralysis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Parosmia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Peripheral swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Personality change 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Topiramate Petechiae 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Photophobia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Topiramate Pneumonia aspiration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Topiramate Pneumonitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Topiramate Pollakiuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Polyuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Poor quality sleep 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Topiramate Premature delivery 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Productive cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Topiramate Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Topiramate Pruritus generalised 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Pulmonary embolism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Topiramate Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Rash papular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Rash pruritic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Renal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Topiramate Respiratory disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Topiramate Restless legs syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Retinal detachment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Rhabdomyolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Topiramate Rhinorrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Sensory disturbance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Septic shock 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Topiramate Shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Topiramate Sinusitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Topiramate Skin burning sensation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Skin disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Skin exfoliation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Skin odour abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Sleep disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Sluggishness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Somnolence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Sopor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Topiramate Speech disorder 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Topiramate Status epilepticus 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Topiramate Stress 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Suicidal ideation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Topiramate Suicide attempt 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Topiramate Systemic lupus erythematosus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Tachycardia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Topiramate Tachypnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Topiramate Tension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Thirst 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Topiramate Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Treatment failure 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Topiramate Tremor 0.0 0.0 0.0 0.0 1.0 0.0 1.0 Topiramate Unevaluable event 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Unresponsive to stimuli 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Topiramate Urine abnormality 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Urticaria 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Topiramate Vertigo 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Topiramate Visual acuity reduced 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Visual field defect 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Weight decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Topiramate Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Wheezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Topiramate White blood cell count decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Topiramate Withdrawal syndrome 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Topotecan hydrochloride Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Topotecan hydrochloride Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Topotecan hydrochloride Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Topotecan hydrochloride Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Topotecan hydrochloride Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Topotecan hydrochloride Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Topotecan hydrochloride Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Topotecan hydrochloride Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Topotecan hydrochloride Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Topotecan hydrochloride Diarrhoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Topotecan hydrochloride Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Topotecan hydrochloride Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Topotecan hydrochloride Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Topotecan hydrochloride Febrile neutropenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Topotecan hydrochloride Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Topotecan hydrochloride Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Topotecan hydrochloride Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Topotecan hydrochloride Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Topotecan hydrochloride Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Topotecan hydrochloride Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Topotecan hydrochloride Myalgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Topotecan hydrochloride Nausea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Topotecan hydrochloride Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Topotecan hydrochloride Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Topotecan hydrochloride Pancytopenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Topotecan hydrochloride Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Topotecan hydrochloride Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Topotecan hydrochloride Rash 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Topotecan hydrochloride Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Topotecan hydrochloride Sepsis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Topotecan hydrochloride Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Topotecan hydrochloride Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Torsemide Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Torsemide Asthenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Torsemide Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Torsemide Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Torsemide Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Torsemide Cough 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Torsemide Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Torsemide Diarrhoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Torsemide Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Torsemide Electrocardiogram abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Torsemide Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Torsemide Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Torsemide Hyperglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Torsemide Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Torsemide Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Torsemide Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Torsemide Hypovolaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Torsemide Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Torsemide Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Torsemide Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Torsemide Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Torsemide Thirst 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Torsemide Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Torsemide Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Acute kidney injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Trabectedin Acute myeloid leukaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Trabectedin Acute pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Acute respiratory distress syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Alanine aminotransferase increased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Anaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Aspartate aminotransferase increased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Asthenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Trabectedin Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Blood albumin decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Blood alkaline phosphatase increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Blood bilirubin increased 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Trabectedin Blood creatine phosphokinase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trabectedin Blood creatinine increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Trabectedin Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Trabectedin Cardiac failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Cough 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Trabectedin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Trabectedin Decreased appetite 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Diarrhoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Drug-induced liver injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Trabectedin Dyspnoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Trabectedin Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trabectedin Febrile neutropenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Gamma-glutamyltransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trabectedin Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Hepatic enzyme increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Trabectedin Hepatic function abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trabectedin Hepatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Hepatotoxicity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Trabectedin Hypoalbuminaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trabectedin Liver function test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Lung infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Malaise 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Trabectedin Myalgia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trabectedin Neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Trabectedin Neutrophil count decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Oedema peripheral 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Trabectedin Pancytopenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Platelet count decreased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Pneumonitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Pulmonary embolism 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Trabectedin Renal impairment 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Trabectedin Respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trabectedin Rhabdomyolysis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Trabectedin Septic shock 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Stomatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Trabectedin Transaminases increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trabectedin Vomiting 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Abdominal distension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Acidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tramadol Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tramadol Acute pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Aggression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Agitation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Agranulocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Alanine aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Altered state of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tramadol Amnesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tramadol Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tramadol Apnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tramadol Arthralgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tramadol Arthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol Aspartate aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Asphyxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tramadol Asthenia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Tramadol Ataxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Atrial fibrillation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tramadol Blister 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol Blood alkaline phosphatase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Blood cholesterol increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol Blood creatine phosphokinase increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tramadol Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Bone pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tramadol Bradycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tramadol Brain oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Cardiac failure acute 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Cardiogenic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Cerebral haemorrhage 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Cerebrovascular accident 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Chills 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol Cholestasis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tramadol Circulatory collapse 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Cognitive disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Coma 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Tramadol Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tramadol Confusional state 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Tramadol Constipation 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Tramadol Contusion 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Cyanosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tramadol Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tramadol Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Depressed level of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Depressed mood 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tramadol Depression 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Tramadol Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tramadol Discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Disturbance in attention 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tramadol Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tramadol Drug dependence 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Tramadol Drug hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol Drug interaction 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tramadol Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol Dysarthria 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Dyskinesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tramadol Dysphonia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol Dysphoria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Ecchymosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Eczema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Emotional distress 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol Encephalopathy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tramadol Epilepsy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Euphoric mood 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol Faecaloma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tramadol Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Tramadol Flatulence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Gait disturbance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tramadol Gastritis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tramadol Gastrointestinal disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tramadol Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tramadol Generalised tonic-clonic seizure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tramadol Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Hallucination, visual 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol Heart rate increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol Heart rate irregular 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tramadol Hepatic failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Hepatitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Hepatitis fulminant 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Hepatomegaly 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tramadol Hypercalcaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tramadol Hyperkalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Hyperkinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Hyperreflexia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Hypersomnia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tramadol Hypertension 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Tramadol Hypertonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol Hypocalcaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Hypoglycaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tramadol Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tramadol Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tramadol Hypotonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Hypoxia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Inappropriate antidiuretic hormone secretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Influenza like illness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tramadol Injury 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol Intentional self-injury 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Irritability 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Ischaemic stroke 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Joint swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol Lethargy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Liver function test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol Mania 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol Mental disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tramadol Mental impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tramadol Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Metabolic acidosis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Tramadol Migraine 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Miosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tramadol Mood altered 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tramadol Mood swings 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tramadol Movement disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tramadol Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol Musculoskeletal stiffness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tramadol Myalgia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Tramadol Mydriasis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tramadol Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tramadol Myoclonus 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Tramadol Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol Nervous system disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tramadol Nervousness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tramadol Nightmare 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Tramadol Oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tramadol Oedema peripheral 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tramadol Osteoporosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tramadol Oxygen saturation decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol Pallor 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Panic attack 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol Paraesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tramadol Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Pneumonia aspiration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tramadol Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Tramadol Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol Psychotic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Pyrexia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Rash pruritic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tramadol Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Renal impairment 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tramadol Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Respiratory depression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Respiratory distress 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tramadol Restlessness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tramadol Seizure 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Tramadol Sepsis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tramadol Serotonin syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tramadol Shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Sinus tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tramadol Sleep disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol Somnolence 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tramadol Speech disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Status epilepticus 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tramadol Stress 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tramadol Suicide attempt 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tramadol Supraventricular tachycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tramadol Tachypnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Tension 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tramadol Throat irritation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Throat tightness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tramadol Thrombocytopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tramadol Thrombocytopenic purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Tinnitus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tramadol Tooth disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tramadol Transaminases increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Tremor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tramadol Troponin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Unevaluable event 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tramadol Unresponsive to stimuli 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Urinary incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Urinary retention 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tramadol Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Vascular purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Ventricular extrasystoles 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol Vertigo 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Tramadol Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol Visual impairment 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Tramadol Vomiting 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Tramadol Weight decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol Withdrawal syndrome 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Tramadol hydrochloride Abdominal distension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol hydrochloride Abdominal pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Abdominal pain lower 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Abdominal pain upper 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol hydrochloride Agitation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tramadol hydrochloride Amnesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol hydrochloride Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol hydrochloride Arrhythmia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol hydrochloride Aspartate aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol hydrochloride Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Chest pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tramadol hydrochloride Chills 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol hydrochloride Cholelithiasis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tramadol hydrochloride Cognitive disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Confusional state 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Tramadol hydrochloride Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol hydrochloride Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Depersonalisation/derealisation disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tramadol hydrochloride Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol hydrochloride Disturbance in attention 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tramadol hydrochloride Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol hydrochloride Drug abuse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol hydrochloride Dysarthria 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tramadol hydrochloride Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tramadol hydrochloride Electrocardiogram abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Faecaloma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol hydrochloride Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol hydrochloride Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Hallucination 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol hydrochloride Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol hydrochloride Hepatic enzyme increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Hepatic failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Hepatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Hot flush 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tramadol hydrochloride Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tramadol hydrochloride Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Hypertonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol hydrochloride Irritability 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Mental impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tramadol hydrochloride Miosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol hydrochloride Nervousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Nightmare 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tramadol hydrochloride Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Pallor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol hydrochloride Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol hydrochloride Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Sedation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Serotonin syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Sleep disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol hydrochloride Somnolence 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Suicidal ideation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tramadol hydrochloride Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol hydrochloride Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol hydrochloride Urinary retention 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Tramadol hydrochloride Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Tramadol hydrochloride Visual impairment 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tramadol hydrochloride Vomiting 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Trametinib Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Trametinib Acne 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Trametinib Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Trametinib Alanine aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Trametinib Arthralgia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trametinib Aspartate aminotransferase increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Trametinib Asthenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trametinib Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Back pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Trametinib Blood creatinine increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Trametinib Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trametinib Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Trametinib Cellulitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trametinib Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Trametinib Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Trametinib Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Confusional state 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Trametinib Constipation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trametinib Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trametinib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Trametinib Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Trametinib Dehydration 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Trametinib Diarrhoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Trametinib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Trametinib Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Dry mouth 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Dry skin 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trametinib Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Dyspnoea 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Trametinib Electrocardiogram QT prolonged 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Trametinib Embolism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Trametinib Epistaxis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trametinib Febrile neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Trametinib Haematuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Trametinib Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Hepatic enzyme increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trametinib Hepatic failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Hyperglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Hyperkalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trametinib Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Hypoalbuminaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Trametinib Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Trametinib Hypophosphataemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Trametinib Hypoxia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Trametinib Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Influenza like illness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Intestinal perforation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Left ventricular dysfunction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trametinib Lip swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Liver function test increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Lung infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Lymphopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trametinib Malignant melanoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Trametinib Malignant neoplasm progression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Trametinib Melaena 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Metastases to central nervous system 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Trametinib Metastases to liver 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Trametinib Metastases to lung 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Trametinib Mucosal inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Trametinib Muscular weakness 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Myalgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Trametinib Nasopharyngitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Trametinib Nausea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Trametinib Oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trametinib Oedema peripheral 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trametinib Oral disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Osteomyelitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Pancytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Platelet count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Pleural effusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Trametinib Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Trametinib Pneumonitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Trametinib Productive cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Pulmonary embolism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trametinib Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Renal failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trametinib Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Trametinib Rhabdomyolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trametinib Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trametinib Sepsis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Trametinib Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Trametinib Skin disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Trametinib Skin exfoliation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Trametinib Stomatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Supraventricular tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Syncope 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Trametinib Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trametinib Tremor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trametinib Upper respiratory tract infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trametinib Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib dimethyl sulfoxide Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib dimethyl sulfoxide Arthralgia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trametinib dimethyl sulfoxide Asthenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Trametinib dimethyl sulfoxide Cerebral haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib dimethyl sulfoxide Constipation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Trametinib dimethyl sulfoxide Cough 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Trametinib dimethyl sulfoxide Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Trametinib dimethyl sulfoxide Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib dimethyl sulfoxide Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib dimethyl sulfoxide Dry skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Trametinib dimethyl sulfoxide Fatigue 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Trametinib dimethyl sulfoxide Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Trametinib dimethyl sulfoxide Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib dimethyl sulfoxide Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib dimethyl sulfoxide Pyrexia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib dimethyl sulfoxide Renal failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib dimethyl sulfoxide Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib dimethyl sulfoxide Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trametinib dimethyl sulfoxide Vomiting 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Trandolapril Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trandolapril Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trandolapril Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trandolapril Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trandolapril Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trandolapril Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tranexamic acid Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tranexamic acid Acute kidney injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tranexamic acid Acute myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tranexamic acid Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tranexamic acid Anaphylactic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tranexamic acid Aphasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tranexamic acid Atrial fibrillation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tranexamic acid Back pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tranexamic acid Blood pressure decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tranexamic acid Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tranexamic acid Cerebral infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tranexamic acid Chest pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tranexamic acid Circulatory collapse 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tranexamic acid Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tranexamic acid Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tranexamic acid Deep vein thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tranexamic acid Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tranexamic acid Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tranexamic acid Embolism 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Tranexamic acid Epilepsy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tranexamic acid Generalised tonic-clonic seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tranexamic acid Haemodynamic instability 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tranexamic acid Heart rate increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tranexamic acid Hypertension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tranexamic acid Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tranexamic acid Hypoxia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tranexamic acid Malaise 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tranexamic acid Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tranexamic acid Muscle spasms 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tranexamic acid Muscular weakness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tranexamic acid Myoclonus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tranexamic acid Obstructive airways disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tranexamic acid Pulmonary embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tranexamic acid Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tranexamic acid Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tranexamic acid Seizure 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Tranexamic acid Status epilepticus 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tranexamic acid Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tranexamic acid Thrombocytopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tranexamic acid Thrombosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tranexamic acid Vasodilatation 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Tranexamic acid Ventricular tachycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tranexamic acid Vomiting 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Travoprost Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Travoprost Asthenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Travoprost Blindness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Travoprost Blood pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Travoprost Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Travoprost Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Travoprost Confusional state 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Travoprost Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Travoprost Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Travoprost Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Travoprost Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Travoprost Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Travoprost Dry eye 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Travoprost Eye disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Travoprost Eye haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Travoprost Eye irritation 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Travoprost Eye pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Travoprost Eye pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Travoprost Feeling abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Travoprost Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Travoprost Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Travoprost Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Travoprost Hypoacusis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Travoprost Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Travoprost Intraocular pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Travoprost Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Travoprost Neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Travoprost Ocular hyperaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Travoprost Photophobia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Travoprost Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Travoprost Retinal detachment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Travoprost Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Travoprost Visual acuity reduced 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Travoprost Visual field defect 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Travoprost Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Trazodone hydrochloride Agitation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Trazodone hydrochloride Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Trazodone hydrochloride Arrhythmia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trazodone hydrochloride Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Trazodone hydrochloride Atrioventricular block 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trazodone hydrochloride Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trazodone hydrochloride Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Trazodone hydrochloride Chest pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Trazodone hydrochloride Confusional state 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Trazodone hydrochloride Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Trazodone hydrochloride Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Trazodone hydrochloride Dyspnoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Trazodone hydrochloride Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trazodone hydrochloride Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Trazodone hydrochloride Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Trazodone hydrochloride Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Trazodone hydrochloride Generalised tonic-clonic seizure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Trazodone hydrochloride Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Trazodone hydrochloride Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Trazodone hydrochloride Hypertension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Trazodone hydrochloride Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trazodone hydrochloride Inappropriate antidiuretic hormone secretion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Trazodone hydrochloride Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Trazodone hydrochloride Malaise 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trazodone hydrochloride Memory impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Trazodone hydrochloride Myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trazodone hydrochloride Nausea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Trazodone hydrochloride Nightmare 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Trazodone hydrochloride Priapism 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Trazodone hydrochloride Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Trazodone hydrochloride Sedation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trazodone hydrochloride Somnolence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Trazodone hydrochloride Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Trazodone hydrochloride Tremor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Treprostinil Abdominal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Abscess 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Acute myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Treprostinil Acute pulmonary oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Treprostinil Acute respiratory failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Aggression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Altered state of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Arrhythmia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Arrhythmia supraventricular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Arthritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Ascites 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Aspiration 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Asthenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Asthma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Atrial flutter 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Atrial septal defect 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Bacteraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Bacterial infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Blister 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Blood count abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Blood disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Blood glucose decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Blood magnesium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Blood potassium increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Blood pressure abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Blood pressure decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Blood pressure fluctuation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Blood sodium decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Bone pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Bradycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Treprostinil Brain injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Treprostinil Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Burning sensation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Treprostinil Cardiac disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Cardiac failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Cardiac failure congestive 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Treprostinil Cardiogenic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Treprostinil Cardiopulmonary failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Treprostinil Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Treprostinil Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Cerebral haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Cerebrovascular accident 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Cholecystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Cholecystitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Chronic kidney disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Chronic obstructive pulmonary disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Circulatory collapse 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Treprostinil Clostridium difficile colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Clostridium difficile infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Cold sweat 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Treprostinil Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Contusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Cyanosis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Treprostinil Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Deep vein thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Delirium 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Depressed mood 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Depression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Dermatitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Treprostinil Dermatitis contact 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Diabetes mellitus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Diabetic ketoacidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Treprostinil Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Diverticulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Dizziness postural 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Drug abuse 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Drug intolerance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Dry mouth 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Dysgeusia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Dyspepsia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Dysphonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Dyspnoea exertional 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Dysstasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Eating disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Encephalopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Epistaxis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Erythema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Eye irritation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Eye swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Faeces discoloured 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Failure to thrive 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Feeling abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Feeling cold 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Feeling hot 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Feeling jittery 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Flank pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Flatulence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Fluid overload 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Fluid retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Flushing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Fungal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Gastric disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Gastroenteritis viral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Gastrointestinal haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Gastrooesophageal reflux disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Generalised oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Gout 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Haematemesis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Haematochezia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Haemodynamic instability 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Treprostinil Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Haemoptysis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Heart rate decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Heart rate irregular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Hepatic cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Treprostinil Hepatic cirrhosis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Hepatic encephalopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Treprostinil Hepatic function abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Treprostinil Hernia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Herpes zoster 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Hip fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Hot flush 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Hyperglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Hyperkalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Hypoaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Hypoglycaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Hyponatraemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Hypotension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Hypotonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Hypovolaemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Hypoxia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Ileus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Treprostinil Ill-defined disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Influenza like illness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Interstitial lung disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Treprostinil Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Intestinal perforation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Treprostinil Joint swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Laceration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Limb discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Liver disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Localised infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Lower respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Lung disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Lung infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Treprostinil Lymphadenopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Lymphoedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Malnutrition 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Melaena 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Treprostinil Memory impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Meningitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Mental disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Mental status changes 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Migraine 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Mobility decreased 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Treprostinil Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Treprostinil Muscle spasms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Musculoskeletal chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Musculoskeletal discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Musculoskeletal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Musculoskeletal stiffness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Myalgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Myelodysplastic syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Myocardial infarction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Nasal congestion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Neck pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Treprostinil Nephrolithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Nervousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Night sweats 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Nightmare 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Oedema peripheral 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Oliguria 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Treprostinil Oral candidiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Oral pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Treprostinil Oropharyngeal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Oxygen saturation decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Pain in jaw 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Pallor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Panic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Paraesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Pericardial effusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Pharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Platelet count decreased 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Pleural effusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Pneumonia aspiration 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Pneumothorax 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Polyuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Productive cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Pruritus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Pruritus generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Pulmonary embolism 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Pulmonary fibrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Treprostinil Pulmonary haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Treprostinil Pulmonary hypertension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Pulmonary oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Pyelonephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Rales 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Rectal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Renal disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Renal failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Renal impairment 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Treprostinil Respiratory disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Respiratory distress 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Respiratory failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Respiratory tract congestion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Restless legs syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Restlessness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Retching 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Rhinorrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Sepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Septic shock 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Treprostinil Sinus disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Sinusitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Skin discolouration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Skin infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Skin irritation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Skin lesion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Sleep apnoea syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Treprostinil Sleep disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Small intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Sneezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Somnolence 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Spinal fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Staphylococcal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Subarachnoid haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Subdural haematoma 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Supraventricular tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Systemic lupus erythematosus 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Throat irritation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Throat tightness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Thrombocytopenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Tinnitus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Tooth abscess 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Transient ischaemic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Troponin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Unevaluable event 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Unresponsive to stimuli 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Upper gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Upper limb fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Upper respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Urinary incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Urine output decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Urticaria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Ventricular tachycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Treprostinil Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Vision blurred 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Weight increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil Wheezing 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil White blood cell count increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil sodium Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil sodium Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil sodium Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil sodium Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil sodium Hypotension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Treprostinil sodium Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Treprostinil sodium Pain in jaw 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tretinoin Acute myeloid leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tretinoin Coagulopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tretinoin Death 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tretinoin Disseminated intravascular coagulation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tretinoin Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tretinoin Haemorrhage intracranial 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tretinoin Headache 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Tretinoin Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tretinoin Infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tretinoin Intracranial pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tretinoin Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tretinoin Myocarditis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Tretinoin Pericardial effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tretinoin Pleural effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tretinoin Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tretinoin Pyrexia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tretinoin Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tretinoin Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Tretinoin Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tretinoin Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Tretinoin Thrombocytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Tretinoin Thrombosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Triamcinolone Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Triamcinolone Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone Blindness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Triamcinolone Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Triamcinolone Erythema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Triamcinolone Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Triamcinolone Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone Rash 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone Skin exfoliation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Abdominal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Triamcinolone acetonide Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Triamcinolone acetonide Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Arthropathy 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Asthma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Triamcinolone acetonide Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Blindness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Triamcinolone acetonide Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Triamcinolone acetonide Cough 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Triamcinolone acetonide Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Triamcinolone acetonide Depression 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Triamcinolone acetonide Dermatitis allergic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Triamcinolone acetonide Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Dizziness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Drug dependence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Triamcinolone acetonide Dyspnoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Eczema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Embolism 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Erythema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Eye pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Fatigue 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Glaucoma 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Triamcinolone acetonide Haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Triamcinolone acetonide Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Hyperhidrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Triamcinolone acetonide Hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Hypertension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Hypokalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Triamcinolone acetonide Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Triamcinolone acetonide Infection 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Injection site reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Triamcinolone acetonide Insomnia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Intraocular pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Triamcinolone acetonide Loss of consciousness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Nasal congestion 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Triamcinolone acetonide Nausea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Paraesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Pruritus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Pyrexia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Rash 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Skin exfoliation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Suicidal ideation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Urticaria 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Vertigo 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Visual acuity reduced 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Vomiting 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Weight decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Triamcinolone acetonide Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Triazolam Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Triazolam Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Triazolam Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Triazolam Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Triazolam Delirium 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Triazolam Depressed level of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Triazolam Depression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Triazolam Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Triazolam Drug abuse 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Triazolam Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Triazolam Intentional self-injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Triazolam Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Triazolam Sopor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Triazolam Suicide attempt 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Triazolam Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Triazolam Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trimethoprim Abdominal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Trimethoprim Abdominal pain upper 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Trimethoprim Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Trimethoprim Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trimethoprim Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Trimethoprim Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Trimethoprim Blister 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Trimethoprim Chest discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Trimethoprim Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trimethoprim Decreased appetite 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Trimethoprim Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Trimethoprim Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Trimethoprim Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Trimethoprim Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trimethoprim Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trimethoprim Erythema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Trimethoprim Eye swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Trimethoprim Feeling abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Trimethoprim Headache 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Trimethoprim Hyperkalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Trimethoprim Hypersensitivity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Trimethoprim Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trimethoprim Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Trimethoprim Lip swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Trimethoprim Liver function test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trimethoprim Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Trimethoprim Musculoskeletal stiffness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Trimethoprim Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Trimethoprim Nausea 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Trimethoprim Photophobia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Trimethoprim Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Trimethoprim Pyrexia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Trimethoprim Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Trimethoprim Rash erythematous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Trimethoprim Rash generalised 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Trimethoprim Rash macular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Trimethoprim Rash pruritic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Trimethoprim Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trimethoprim Stevens-Johnson syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trimethoprim Swelling face 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Trimethoprim Swollen tongue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Trimethoprim Throat tightness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trimethoprim Toxic epidermal necrolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Trimethoprim Tremor 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Trimethoprim Urticaria 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Trimethoprim Vomiting 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Trimethoprim Wheezing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Triptorelin Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Triptorelin Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Triptorelin Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Triptorelin Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Triptorelin Injection site pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Triptorelin Mental disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Triptorelin Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Triptorelin Weight increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Triptorelin pamoate Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Triptorelin pamoate Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Trospium chloride Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ulipristal acetate Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ulipristal acetate Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ulipristal acetate Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ulipristal acetate Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Umeclidinium bromide Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Umeclidinium bromide Urinary retention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Umeclidinium bromide Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Upadacitinib Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Upadacitinib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Upadacitinib Deep vein thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Upadacitinib Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Upadacitinib Embolism venous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Upadacitinib Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Upadacitinib Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Upadacitinib Herpes zoster 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Upadacitinib Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Upadacitinib Neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Upadacitinib Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Upadacitinib Peripheral swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Upadacitinib Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Upadacitinib Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Upadacitinib Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Upadacitinib Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Upadacitinib Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Upadacitinib Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ursodiol Abdominal discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ursodiol Asthma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ursodiol Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ursodiol Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ursodiol Depression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ursodiol Diarrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ursodiol Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ursodiol Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ursodiol Hepatic cirrhosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ursodiol Hepatic function abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ursodiol Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ursodiol Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ursodiol Malaise 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ursodiol Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ursodiol Pneumonia 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ursodiol Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ursodiol Rhinitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ursodiol Somnolence 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Ustekinumab Acute coronary syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ustekinumab Angioedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ustekinumab Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ustekinumab Appendicitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ustekinumab Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Ustekinumab Back pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ustekinumab Breast cancer 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Ustekinumab Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ustekinumab Cerebrovascular accident 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ustekinumab Cholecystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ustekinumab Diarrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ustekinumab Diverticulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ustekinumab Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ustekinumab Dyspnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Ustekinumab Facial paralysis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ustekinumab Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ustekinumab Gastroenteritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ustekinumab Haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ustekinumab Headache 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ustekinumab Herpes zoster 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ustekinumab Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ustekinumab Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ustekinumab Injection site pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ustekinumab Injection site reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ustekinumab Malignant melanoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ustekinumab Mental disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ustekinumab Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Ustekinumab Myocardial infarction 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Ustekinumab Nasopharyngitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ustekinumab Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ustekinumab Neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ustekinumab Oropharyngeal pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ustekinumab Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ustekinumab Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ustekinumab Posterior reversible encephalopathy syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ustekinumab Pruritus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ustekinumab Rash 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ustekinumab Sepsis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Ustekinumab Skin cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ustekinumab Swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Ustekinumab Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Ustekinumab Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valacyclovir hydrochloride Abdominal discomfort 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Valacyclovir hydrochloride Abdominal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valacyclovir hydrochloride Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Valacyclovir hydrochloride Aggression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valacyclovir hydrochloride Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valacyclovir hydrochloride Altered state of consciousness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Valacyclovir hydrochloride Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valacyclovir hydrochloride Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valacyclovir hydrochloride Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valacyclovir hydrochloride Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valacyclovir hydrochloride Blood disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valacyclovir hydrochloride Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valacyclovir hydrochloride Confusional state 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Valacyclovir hydrochloride Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valacyclovir hydrochloride Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valacyclovir hydrochloride Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valacyclovir hydrochloride Depressed level of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valacyclovir hydrochloride Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Valacyclovir hydrochloride Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valacyclovir hydrochloride Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valacyclovir hydrochloride Dyspnoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Valacyclovir hydrochloride Encephalopathy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Valacyclovir hydrochloride Face oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valacyclovir hydrochloride Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valacyclovir hydrochloride Feeling abnormal 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valacyclovir hydrochloride Haematuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valacyclovir hydrochloride Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valacyclovir hydrochloride Hallucination, visual 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valacyclovir hydrochloride Headache 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Valacyclovir hydrochloride Herpes simplex 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valacyclovir hydrochloride Hypertension 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valacyclovir hydrochloride Liver function test abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valacyclovir hydrochloride Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valacyclovir hydrochloride Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valacyclovir hydrochloride Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valacyclovir hydrochloride Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valacyclovir hydrochloride Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valacyclovir hydrochloride Psychotic disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valacyclovir hydrochloride Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valacyclovir hydrochloride Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valacyclovir hydrochloride Renal failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valacyclovir hydrochloride Renal impairment 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Valacyclovir hydrochloride Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valacyclovir hydrochloride Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valacyclovir hydrochloride Thrombocytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valacyclovir hydrochloride Tremor 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valacyclovir hydrochloride Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Aggression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Akathisia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Amnesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Anxiety 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Aphasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Aspiration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Balance disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Blood pressure decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valbenazine Cardiac disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Cardiac failure congestive 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valbenazine Catatonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Cerebrovascular accident 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Chronic obstructive pulmonary disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valbenazine Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Contusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Cystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valbenazine Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Delusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Dementia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Depression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Disturbance in attention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Dyskinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Dysphagia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Dysstasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Dystonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Feeding disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Feeling abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Hallucination, auditory 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Hip fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Hypoaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Hypokinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Intentional self-injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Irritability 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Lethargy 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Mania 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Memory impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Mental disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Migraine 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Muscle rigidity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Myocardial infarction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valbenazine Neurological symptom 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Pain in extremity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Palpitations 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Paranoia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Parkinson's disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Parkinsonism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Psychotic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Pulmonary embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Renal failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Renal impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Restless legs syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Restlessness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Salivary hypersecretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Sedation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Sepsis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Speech disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Staphylococcal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Suicidal ideation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Suicide attempt 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Tardive dyskinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Urinary incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Urinary tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Urticaria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Valbenazine Vision blurred 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Visual impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valbenazine Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valganciclovir Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valganciclovir Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valganciclovir Ascites 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valganciclovir Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valganciclovir Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valganciclovir Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valganciclovir Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valganciclovir Drug resistance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Valganciclovir Febrile neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valganciclovir Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valganciclovir Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valganciclovir Leukopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valganciclovir Mouth ulceration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valganciclovir Oedema peripheral 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valganciclovir Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valganciclovir Paraesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valganciclovir Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valganciclovir Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valganciclovir Treatment failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Valganciclovir Weight decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Valganciclovir hydrochloride Anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valganciclovir hydrochloride Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valganciclovir hydrochloride Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valganciclovir hydrochloride Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valganciclovir hydrochloride Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valganciclovir hydrochloride Insomnia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valganciclovir hydrochloride Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valganciclovir hydrochloride Neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valganciclovir hydrochloride Pancytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valganciclovir hydrochloride Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valganciclovir hydrochloride Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Valproate sodium Abdominal pain 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Valproate sodium Affect lability 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Valproate sodium Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valproate sodium Amblyopia 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Valproate sodium Amnesia 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Valproate sodium Asthenia 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Valproate sodium Ataxia 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Valproate sodium Bronchitis 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Valproate sodium Chest pain 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Valproate sodium Constipation 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Valproate sodium Decreased appetite 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Valproate sodium Diarrhoea 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Valproate sodium Dyspepsia 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Valproate sodium Gait disturbance 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Valproate sodium Hallucination 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Valproate sodium Headache 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Valproate sodium Hyperhidrosis 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Valproate sodium Infection 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Valproate sodium Nystagmus 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Valproate sodium Pain 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Valproate sodium Paraesthesia 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Valproate sodium Pharyngitis 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Valproate sodium Pneumonia 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Valproate sodium Pyrexia 0.0 1.0 1.0 0.0 1.0 0.0 0.0 Valproate sodium Rhinitis 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Valproate sodium Somnolence 0.0 0.0 1.0 0.0 1.0 0.0 0.0 Valproate sodium Tremor 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Valproate sodium Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valproate sodium Vomiting 0.0 0.0 1.0 1.0 1.0 0.0 0.0 Valproate sodium Weight decreased 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Valproic acid Abasia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Abdominal distension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Abdominal pain upper 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Valproic acid Abdominal tenderness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Valproic acid Acidosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Acute hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Acute respiratory distress syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Aggression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Agitation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valproic acid Altered state of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Amenorrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valproic acid Amnesia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Anxiety 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Valproic acid Apathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Valproic acid Aphasia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Arrhythmia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Atrial fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Atrial septal defect 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Valproic acid Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Balance disorder 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Valproic acid Blister 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Blood creatine phosphokinase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Bradycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Brain oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid C-reactive protein increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Cardiac murmur 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Valproic acid Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Catatonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Circulatory collapse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Cognitive disorder 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Valproic acid Coma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Confusional state 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Coordination abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Valproic acid Cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Deafness 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Valproic acid Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Deep vein thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Delirium 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Delusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Depressed level of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Depression 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valproic acid Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Valproic acid Disease recurrence 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Valproic acid Disorientation 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Valproic acid Disturbance in attention 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Valproic acid Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Drug abuse 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Drug interaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Dysarthria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Dyskinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valproic acid Dysphagia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Dysphonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Ear disorder 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Valproic acid Eating disorder 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Valproic acid Ecchymosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Encephalopathy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Epilepsy 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Valproic acid Extrapyramidal disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Fatigue 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Valproic acid Foetal growth restriction 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Valproic acid Gait disturbance 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Valproic acid Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Gastrooesophageal reflux disease 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Valproic acid Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Haemodynamic instability 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Haemoglobin decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Hepatic function abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Hepatic steatosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Hepatotoxicity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Hyperhidrosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Hyperkalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Hypernatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Hypertonia 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Valproic acid Hypoacusis 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Valproic acid Hypoalbuminaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Hypocalcaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Hypoglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Hypothermia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Hypothyroidism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Hypotonia 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Valproic acid Ileus paralytic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Insomnia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Intentional self-injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Intracranial pressure increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Irritability 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Lactic acidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Lethargy 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Leukocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Liver disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Liver injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Lymphadenopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Mania 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Memory impairment 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Valproic acid Mental status changes 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Metabolic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Metabolic disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Motor dysfunction 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Valproic acid Movement disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Muscle rigidity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Musculoskeletal stiffness 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Valproic acid Mydriasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Nervous system disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Neuroleptic malignant syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Orthostatic hypotension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Osteoporosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Otitis media 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Valproic acid Pain in extremity 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Valproic acid Pancreatitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Pancytopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Parkinsonism 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valproic acid Pleural effusion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Pneumonia aspiration 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Valproic acid Psychomotor hyperactivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Psychotic disorder 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Pulmonary alveolar haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Pulmonary embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Pulmonary hypertension 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Valproic acid Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Rash 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Rash generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Rash maculo-papular 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Respiratory depression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Respiratory distress 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Respiratory failure 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Rhabdomyolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Salivary hypersecretion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Sedation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Seizure 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Valproic acid Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Serotonin syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Sinus tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Somnolence 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Sopor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Speech disorder 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Valproic acid Status epilepticus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Stevens-Johnson syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Sudden death 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Suicide attempt 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Thrombocytopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Tooth disorder 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Valproic acid Toxic epidermal necrolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Transaminases increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Treatment failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Valproic acid Tremor 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Valproic acid Unresponsive to stimuli 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Upper respiratory tract infection 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Valproic acid Urinary incontinence 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Valproic acid Urinary tract infection 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Valproic acid Visual impairment 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Valproic acid Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valproic acid Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valproic acid White blood cell count increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valproic acid Withdrawal syndrome 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Valsartan Abasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Abdominal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Abdominal distension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Abdominal pain 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Valsartan Abdominal pain upper 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Valsartan Acute myeloid leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valsartan Acute myocardial infarction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Agitation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Valsartan Anal incontinence 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Anaphylactic reaction 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Valsartan Angioedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Anuria 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Valsartan Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Valsartan Arthralgia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Valsartan Arthropathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Ascites 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Valsartan Atrial fibrillation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Valsartan Atrial septal defect 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Valsartan Atrioventricular block complete 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Balance disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Basal cell carcinoma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Blood cholesterol increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Blood creatine phosphokinase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Blood creatinine increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Blood glucose increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Blood potassium increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Blood pressure abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Blood pressure decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Blood pressure fluctuation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Valsartan Blood pressure increased 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Valsartan Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Blood triglycerides increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Valsartan Blood urea increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Blood uric acid increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Bradycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Brain injury 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Valsartan Breast cancer 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Valsartan C-reactive protein increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Valsartan Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Cardiac failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Valsartan Cardiac failure acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Cardiomegaly 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Cardiovascular disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Cataract 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valsartan Chest discomfort 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Cholecystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Cholelithiasis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Cholestasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Chromaturia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valsartan Chronic kidney disease 1.0 1.0 0.0 0.0 1.0 0.0 0.0 Valsartan Circulatory collapse 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Cognitive disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Cold sweat 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Colon cancer 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valsartan Confusional state 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Coronary artery disease 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Cystitis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Deafness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Valsartan Death 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Valsartan Decreased appetite 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Valsartan Deep vein thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Depressed level of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Depressed mood 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Valsartan Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Valsartan Dermatitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Dermatitis exfoliative 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Valsartan Diarrhoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Disorientation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valsartan Disturbance in attention 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Drug abuse 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Drug hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Drug intolerance 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Drug-induced liver injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Duodenal ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Dysgeusia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Dysphagia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Dysphonia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Valsartan Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Dysuria 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Valsartan Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Emotional distress 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Valsartan Encephalopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Erectile dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Erythema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Eye pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Valsartan Face oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Fear 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Valsartan Feeling abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Flatulence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Foetal growth restriction 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Valsartan Fracture 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Gait disturbance 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Valsartan Gamma-glutamyltransferase increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Gastric cancer 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Valsartan Gastritis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Gastroenteritis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Gastrooesophageal reflux disease 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Glaucoma 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Gout 1.0 1.0 0.0 1.0 1.0 0.0 0.0 Valsartan Haematochezia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Haemoglobin decreased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Valsartan Haemoptysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valsartan Haemorrhoids 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Valsartan Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Headache 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Valsartan Heart rate decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Hepatic cancer 1.0 0.0 0.0 1.0 0.0 0.0 1.0 Valsartan Hepatic cirrhosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valsartan Hepatic failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Hepatic steatosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Hepatocellular injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Hepatomegaly 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Hip fracture 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Hyperkalaemia 0.0 1.0 1.0 0.0 1.0 0.0 0.0 Valsartan Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Hypertensive crisis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Hyperthyroidism 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Hypoacusis 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Valsartan Hypoalbuminaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Hypocalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Hypokalaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Valsartan Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Hypotension 0.0 1.0 1.0 0.0 1.0 0.0 0.0 Valsartan Hypothyroidism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Ileus 1.0 1.0 0.0 0.0 1.0 0.0 0.0 Valsartan Ill-defined disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Inappropriate antidiuretic hormone secretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Incontinence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valsartan Infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Inflammation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Valsartan Influenza 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Valsartan Influenza like illness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Valsartan Insomnia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Interstitial lung disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Intraocular pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Valsartan Irritability 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Valsartan Ischaemic stroke 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Jaundice 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Joint swelling 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Lactic acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Lethargy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Valsartan Leukocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Limb discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Liver injury 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Loss of libido 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Lung disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valsartan Lung neoplasm malignant 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Lymphadenopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Lymphatic disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valsartan Lymphocyte count decreased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Lymphoedema 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Lymphoma 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Valsartan Malaise 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Valsartan Malignant melanoma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Melaena 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Memory impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Mental disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Mental impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Valsartan Metabolic acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Metastases to central nervous system 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Metastases to liver 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valsartan Mitral valve incompetence 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Valsartan Mobility decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valsartan Movement disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valsartan Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Musculoskeletal discomfort 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Valsartan Musculoskeletal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Musculoskeletal stiffness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Myalgia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valsartan Myocardial ischaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Neck pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Neoplasm 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Valsartan Nephropathy toxic 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Valsartan Nervous system disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Neuropathy peripheral 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Valsartan Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Oedema peripheral 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Oliguria 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Valsartan Oral disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Oropharyngeal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Osteoarthritis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Osteoporosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Oxygen saturation decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Pain in extremity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Valsartan Palpitations 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Pancreatic carcinoma 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Pancreatitis acute 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Paraesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Valsartan Paralysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valsartan Peripheral swelling 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Pharyngeal oedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Valsartan Pharyngitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Valsartan Pigmentation disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Valsartan Platelet count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Pleural effusion 1.0 1.0 0.0 0.0 1.0 0.0 0.0 Valsartan Pneumonia 1.0 1.0 0.0 0.0 1.0 0.0 0.0 Valsartan Pneumonia aspiration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Pneumonitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Valsartan Pneumothorax 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Valsartan Polyneuropathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Premature baby 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Valsartan Premature delivery 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Valsartan Productive cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Prostate cancer 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Valsartan Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Pruritus generalised 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Valsartan Pulmonary embolism 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Pulmonary hypertension 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Valsartan Pyrexia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Valsartan Rash 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Rash pruritic 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Renal disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valsartan Renal failure 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Valsartan Respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valsartan Respiratory disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Respiratory distress 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Valsartan Respiratory failure 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Rhabdomyolysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valsartan Rheumatoid arthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Shock 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Valsartan Sinus bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Sinus tachycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Valsartan Skin disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Sleep apnoea syndrome 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Valsartan Sleep disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Stevens-Johnson syndrome 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Valsartan Subdural haematoma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Swelling 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Swelling face 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Syncope 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Valsartan Systemic lupus erythematosus 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Tachycardia 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Valsartan Tendon rupture 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Tinnitus 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Transaminases increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Valsartan Transient ischaemic attack 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Valsartan Urinary retention 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Urinary tract infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Urine output decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Varicose vein 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Ventricular extrasystoles 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Visual impairment 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Valsartan Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Valsartan Weight decreased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Valsartan Weight increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vancomycin Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Vancomycin Agranulocytosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Vancomycin Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Vancomycin Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vancomycin Anaphylactoid reaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vancomycin Asthenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Vancomycin Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vancomycin Blood creatinine increased 0.0 1.0 1.0 1.0 0.0 1.0 0.0 Vancomycin Bradycardia 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Vancomycin Chills 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Vancomycin Clostridium difficile colitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Vancomycin Dermatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vancomycin Dermatitis bullous 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vancomycin Dermatitis exfoliative 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vancomycin Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Vancomycin Drug eruption 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Vancomycin Dyspnoea 1.0 1.0 0.0 0.0 0.0 1.0 0.0 Vancomycin Eosinophilia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Vancomycin Erythema 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Vancomycin Erythema multiforme 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vancomycin Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vancomycin Flushing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vancomycin Fungal infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vancomycin Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vancomycin Hypersensitivity 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Vancomycin Hypoacusis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Vancomycin Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vancomycin Hypotension 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Vancomycin Infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Vancomycin Nausea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Vancomycin Nervous system disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vancomycin Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vancomycin Oedema peripheral 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Vancomycin Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vancomycin Pruritus 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Vancomycin Pyrexia 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Vancomycin Rash 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Vancomycin Rash macular 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Vancomycin Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Vancomycin Renal impairment 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Vancomycin Stevens-Johnson syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Vancomycin Tachycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Vancomycin Thrombocytopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Vancomycin Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Vancomycin Toxic epidermal necrolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Vancomycin Tubulointerstitial nephritis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Vancomycin Urticaria 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Vancomycin Vomiting 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Vancomycin Wheezing 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vancomycin hydrochloride Acute kidney injury 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Vancomycin hydrochloride Anaphylactic reaction 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Vancomycin hydrochloride Anaphylactic shock 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vancomycin hydrochloride Blood creatinine increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Vancomycin hydrochloride Blood urea increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vancomycin hydrochloride Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vancomycin hydrochloride Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vancomycin hydrochloride Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vancomycin hydrochloride Erythema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vancomycin hydrochloride Erythema multiforme 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vancomycin hydrochloride Flushing 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vancomycin hydrochloride Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vancomycin hydrochloride Nausea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Vancomycin hydrochloride Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vancomycin hydrochloride Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vancomycin hydrochloride Pruritus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vancomycin hydrochloride Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Vancomycin hydrochloride Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vancomycin hydrochloride Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Vancomycin hydrochloride Renal impairment 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Vancomycin hydrochloride Stevens-Johnson syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vancomycin hydrochloride Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vancomycin hydrochloride Toxic epidermal necrolysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Vancomycin hydrochloride Urticaria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vandetanib Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vandetanib Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vandetanib Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vandetanib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vandetanib Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vandetanib Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vandetanib Dermatitis bullous 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vandetanib Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vandetanib Epistaxis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vandetanib Erythema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vandetanib Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vandetanib Hypertension 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Vandetanib Hypocalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vandetanib Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vandetanib Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vandetanib Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vandetanib Peritonitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vandetanib Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vandetanib Pyelonephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vandetanib Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vandetanib Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vandetanib Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Varenicline Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Varenicline tartrate Abnormal dreams 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Varenicline tartrate Aggression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Amnesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Anaemia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Angina pectoris 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Angioedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Varenicline tartrate Anxiety 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Arrhythmia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Arthritis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Varenicline tartrate Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Varenicline tartrate Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Balance disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Cerebrovascular accident 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Chest pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Constipation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Varenicline tartrate Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Varenicline tartrate Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Delusion 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Depression 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Varenicline tartrate Diabetes mellitus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Varenicline tartrate Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Dysgeusia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Erectile dysfunction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Varenicline tartrate Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Hallucination 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Varenicline tartrate Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Hot flush 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Hyperhidrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Varenicline tartrate Insomnia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Lethargy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Liver function test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Varenicline tartrate Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Mania 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Varenicline tartrate Migraine 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Mood swings 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Varenicline tartrate Nausea 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Varenicline tartrate Nightmare 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Varenicline tartrate Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Varenicline tartrate Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Varenicline tartrate Panic attack 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Paranoia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Pruritus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Psychotic disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Rash 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Varenicline tartrate Sleep disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Somnolence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Varenicline tartrate Stevens-Johnson syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Varenicline tartrate Suicidal ideation 0.0 1.0 0.0 1.0 0.0 0.0 1.0 Varenicline tartrate Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Varenicline tartrate Syncope 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Thinking abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Thrombosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Tinnitus 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Varenicline tartrate Transient ischaemic attack 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Tremor 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Varenicline tartrate Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Varenicline tartrate Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Vemurafenib Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Acne 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib Acute coronary syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Acute myocardial infarction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib Alanine aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vemurafenib Anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib Arthralgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vemurafenib Ascites 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib Aspartate aminotransferase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib Asthenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Back pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib Basal cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vemurafenib Blood alkaline phosphatase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib Blood creatine phosphokinase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Blood creatinine increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib Blood lactate dehydrogenase increased 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Vemurafenib Brain oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib Cardiac disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Cardiac failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Cerebral haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib Cerebrovascular accident 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Cheilitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Chest discomfort 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Chills 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib Colitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib Confusional state 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Conjunctivitis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Vemurafenib Cough 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Vemurafenib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Depression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vemurafenib Dermatitis exfoliative 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib Disseminated intravascular coagulation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Dizziness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib Drug eruption 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Drug-induced liver injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Dry skin 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vemurafenib Duodenal ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Dysgeusia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Vemurafenib Dysphagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Epilepsy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib Erythema multiforme 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Face oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Facial paralysis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Vemurafenib Febrile neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Gastrointestinal haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib Hepatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Hepatocellular injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Hepatotoxicity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib Herpes zoster 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Hyperbilirubinaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vemurafenib Hyperglycaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib Hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Hyperthermia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Hypoaesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vemurafenib Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Insomnia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib Joint swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vemurafenib Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Leukocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Lung disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Lymphopenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vemurafenib Malaise 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Vemurafenib Malignant melanoma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib Mass 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vemurafenib Metastases to central nervous system 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vemurafenib Mucosal inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib Muscular weakness 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Vemurafenib Myocardial infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Nausea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib Neoplasm malignant 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vemurafenib Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vemurafenib Neutrophil count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib Nystagmus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Ocular hyperaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vemurafenib Oedema peripheral 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib Oesophagitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Osteoarthritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib Pain in extremity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Vemurafenib Pancreatitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Pancreatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Pericardial effusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Pericarditis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Photosensitivity reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vemurafenib Pleural effusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Pneumonitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Pneumothorax 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Poor quality sleep 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vemurafenib Pulmonary embolism 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Vemurafenib Purpura 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Rash erythematous 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Rash generalised 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Rash maculo-papular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Rash papular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vemurafenib Rash pustular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vemurafenib Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Seizure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib Sepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Skin cancer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vemurafenib Skin infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib Squamous cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vemurafenib Syncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Toxic epidermal necrolysis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Toxic skin eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Urinary tract infection 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Vertigo 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Vision blurred 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Vemurafenib Vomiting 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Vemurafenib Weight decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Vemurafenib White blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Abdominal pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Abdominal pain upper 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Acute kidney injury 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Acute myeloid leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Agranulocytosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Anxiety 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Appendicitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Arrhythmia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Arthralgia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Arthropathy 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Venetoclax Asthenia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Atrial fibrillation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Back pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Bacterial infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Basal cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Venetoclax Blood albumin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Blood count abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Blood creatinine increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Blood lactate dehydrogenase increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Blood magnesium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Blood potassium increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Blood pressure abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Blood urea increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Blood uric acid increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Bone marrow failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Bone pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Bradycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Bronchitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax C-reactive protein increased 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Candida infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Cardiac disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Cardiac failure 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Cardiac failure congestive 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Cardiomyopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Cardiopulmonary failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Cellulitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Cerebral haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Cerebrovascular accident 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Chills 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Cholecystitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Cholestasis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Chronic obstructive pulmonary disease 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Clostridium difficile infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Colitis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Confusional state 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Constipation 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Cough 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Cystitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Deafness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Venetoclax Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Decreased appetite 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Deep vein thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Depressed level of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Depression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Diarrhoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Dizziness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Drug intolerance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Dysphagia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Ecchymosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Enteritis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Failure to thrive 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Febrile neutropenia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Fluid overload 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Full blood count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Fungal infection 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Gait disturbance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Gastric haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Gastrointestinal haemorrhage 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Gastrooesophageal reflux disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Gout 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Haematochezia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Haemolysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Haemolytic anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Haemoptysis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Haemorrhage intracranial 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Heart rate irregular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Hepatic function abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Hepatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Hepatomegaly 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Herpes zoster 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Hyperbilirubinaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Hypercalcaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Hyperglycaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Hyperkalaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Hypertension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Hypokalaemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Hyponatraemia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Hypophagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Hypophosphataemia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Hypotension 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Hypoxia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Ileus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Ill-defined disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Jaundice 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Jaundice cholestatic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Laboratory test abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Leukocytosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Liver disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Liver function test increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Localised infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Loss of consciousness 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Lower respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Lung disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Lung infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Lung infiltration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Lymphadenopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Lymphoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Malaise 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Malnutrition 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Memory impairment 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Mental status changes 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Metabolic acidosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Mobility decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Mucosal inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Muscular weakness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Myelodysplastic syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Myocardial infarction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Nausea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Neoplasm 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Nervous system disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Neutropenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Neutrophil count decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Oedema peripheral 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Oropharyngeal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Pericardial effusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Plasma cell myeloma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Platelet count decreased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Pleural effusion 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Pneumonia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Pneumonia bacterial 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Pneumonitis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Pulmonary alveolar haemorrhage 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Pulmonary embolism 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Pulmonary mass 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Pulmonary oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Pyrexia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Rash 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Rash pruritic 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Red blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Renal failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Renal impairment 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Respiratory disorder 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Respiratory distress 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Respiratory tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Sepsis 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Sinusitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Somnolence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Speech disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Splenomegaly 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Stomatitis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Subarachnoid haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Subdural haematoma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Tachycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Tachypnoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Thrombosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Transient ischaemic attack 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Treatment failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Tumour lysis syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Unevaluable event 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Upper respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Urosepsis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Vertigo 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Visual impairment 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Venetoclax Vomiting 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax Weight increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax White blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venetoclax White blood cell count increased 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Venlafaxine hydrochloride Abdominal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Venlafaxine hydrochloride Abnormal dreams 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Venlafaxine hydrochloride Accommodation disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Venlafaxine hydrochloride Agitation 0.0 1.0 1.0 0.0 1.0 0.0 0.0 Venlafaxine hydrochloride Agranulocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Venlafaxine hydrochloride Akathisia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Venlafaxine hydrochloride Alopecia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Venlafaxine hydrochloride Angioedema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Venlafaxine hydrochloride Apathy 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Venlafaxine hydrochloride Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Venlafaxine hydrochloride Balance disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Venlafaxine hydrochloride Blood pressure increased 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Venlafaxine hydrochloride Chills 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Venlafaxine hydrochloride Confusional state 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Venlafaxine hydrochloride Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Venlafaxine hydrochloride Coordination abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Venlafaxine hydrochloride Decreased appetite 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Venlafaxine hydrochloride Delirium 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Venlafaxine hydrochloride Depersonalisation/derealisation disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Venlafaxine hydrochloride Diarrhoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Venlafaxine hydrochloride Dizziness 0.0 1.0 0.0 1.0 0.0 1.0 1.0 Venlafaxine hydrochloride Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Venlafaxine hydrochloride Dysgeusia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Venlafaxine hydrochloride Dyskinesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Venlafaxine hydrochloride Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Venlafaxine hydrochloride Dyspnoea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Venlafaxine hydrochloride Dystonia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Venlafaxine hydrochloride Dysuria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Venlafaxine hydrochloride Electrocardiogram QT prolonged 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Venlafaxine hydrochloride Epistaxis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venlafaxine hydrochloride Erectile dysfunction 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Venlafaxine hydrochloride Gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Venlafaxine hydrochloride Hallucination 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Venlafaxine hydrochloride Headache 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Venlafaxine hydrochloride Hepatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venlafaxine hydrochloride Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Venlafaxine hydrochloride Hypertension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Venlafaxine hydrochloride Hypertonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Venlafaxine hydrochloride Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Venlafaxine hydrochloride Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Venlafaxine hydrochloride Inappropriate antidiuretic hormone secretion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Venlafaxine hydrochloride Insomnia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Venlafaxine hydrochloride Interstitial lung disease 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Venlafaxine hydrochloride Libido decreased 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Venlafaxine hydrochloride Liver function test abnormal 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Venlafaxine hydrochloride Mania 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Venlafaxine hydrochloride Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Venlafaxine hydrochloride Mydriasis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Venlafaxine hydrochloride Myoclonus 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Venlafaxine hydrochloride Nausea 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Venlafaxine hydrochloride Nervousness 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Venlafaxine hydrochloride Neuroleptic malignant syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Venlafaxine hydrochloride Neutropenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Venlafaxine hydrochloride Night sweats 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Venlafaxine hydrochloride Palpitations 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Venlafaxine hydrochloride Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venlafaxine hydrochloride Paraesthesia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Venlafaxine hydrochloride Photosensitivity reaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Venlafaxine hydrochloride Pollakiuria 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Venlafaxine hydrochloride Pruritus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Venlafaxine hydrochloride Rhabdomyolysis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Venlafaxine hydrochloride Seizure 0.0 1.0 1.0 0.0 1.0 0.0 0.0 Venlafaxine hydrochloride Serotonin syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Venlafaxine hydrochloride Skin disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Venlafaxine hydrochloride Somnolence 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Venlafaxine hydrochloride Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Venlafaxine hydrochloride Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Venlafaxine hydrochloride Tardive dyskinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Venlafaxine hydrochloride Thrombocytopenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Venlafaxine hydrochloride Tinnitus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Venlafaxine hydrochloride Tremor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Venlafaxine hydrochloride Urinary incontinence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Venlafaxine hydrochloride Urinary retention 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Venlafaxine hydrochloride Urticaria 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Venlafaxine hydrochloride Ventricular fibrillation 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Venlafaxine hydrochloride Ventricular tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Venlafaxine hydrochloride Visual impairment 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Venlafaxine hydrochloride Vomiting 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Venlafaxine hydrochloride Weight decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Venlafaxine hydrochloride Weight increased 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Verapamil hydrochloride Atrioventricular block complete 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Verapamil hydrochloride Bradycardia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Verapamil hydrochloride Confusional state 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Verapamil hydrochloride Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Verapamil hydrochloride Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Verapamil hydrochloride Dyspnoea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Verapamil hydrochloride Headache 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Verapamil hydrochloride Hyperhidrosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Verapamil hydrochloride Hypotension 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Verapamil hydrochloride Muscle spasms 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Verapamil hydrochloride Nausea 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Verapamil hydrochloride Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Verapamil hydrochloride Palpitations 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Verapamil hydrochloride Pulmonary oedema 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Verapamil hydrochloride Somnolence 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Verapamil hydrochloride Syncope 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Verteporfin Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Verteporfin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Verteporfin Disease progression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Verteporfin Retinal detachment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Verteporfin Retinal haemorrhage 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Verteporfin Visual acuity reduced 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Vigabatrin Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Acute respiratory failure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Apnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Asthma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Bacterial infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Blindness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Vigabatrin Bradycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Vigabatrin Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vigabatrin Clostridium difficile infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Cyanosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vigabatrin Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vigabatrin Dyspnoea 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Vigabatrin Ear infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Encephalopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vigabatrin Epilepsy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Failure to thrive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Vigabatrin Feeding disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Gastroenteritis viral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Vigabatrin Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Hypothermia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Hypoxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Influenza 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Insomnia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vigabatrin Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Lung infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Mental status changes 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Muscular weakness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vigabatrin Myoclonus 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vigabatrin Nasal congestion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Nasopharyngitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Nervous system disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Oxygen saturation decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Pneumonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Pneumonia aspiration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Pneumothorax 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Vigabatrin Respiratory disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Respiratory distress 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vigabatrin Respiratory tract infection 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Sedation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Seizure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Sepsis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Somnolence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Vigabatrin Status epilepticus 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Upper respiratory tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Viral infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Vigabatrin Visual acuity reduced 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vigabatrin Visual field defect 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Vigabatrin Visual impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vigabatrin Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vigabatrin Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vilazodone hydrochloride Agitation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vilazodone hydrochloride Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Vilazodone hydrochloride Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vilazodone hydrochloride Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vilazodone hydrochloride Feeling abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vilazodone hydrochloride Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Vilazodone hydrochloride Nausea 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Vilazodone hydrochloride Paraesthesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vilazodone hydrochloride Seizure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vilazodone hydrochloride Serotonin syndrome 0.0 0.0 0.0 0.0 0.0 1.0 0.0 Vilazodone hydrochloride Suicidal ideation 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Vincristine Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vincristine Acute myeloid leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vincristine Alopecia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vincristine Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Vincristine Bone marrow failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vincristine Bone pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vincristine Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vincristine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vincristine Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vincristine Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vincristine Dyspnoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vincristine Extravasation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vincristine Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vincristine Febrile neutropenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vincristine Hepatocellular injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vincristine Hypertension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vincristine Hypoaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vincristine Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vincristine Infection 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Vincristine Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vincristine Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vincristine Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vincristine Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vincristine Myelodysplastic syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vincristine Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vincristine Pancytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vincristine Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Vincristine Posterior reversible encephalopathy syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vincristine Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Vincristine Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Vincristine Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Vincristine Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vincristine Tumour lysis syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vincristine sulfate Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Vincristine sulfate Anaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Vincristine sulfate Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Vincristine sulfate Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Vincristine sulfate Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vincristine sulfate Constipation 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Vincristine sulfate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vincristine sulfate Decreased appetite 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vincristine sulfate Diarrhoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Vincristine sulfate Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vincristine sulfate Febrile neutropenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Vincristine sulfate Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vincristine sulfate Hepatotoxicity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vincristine sulfate Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Vincristine sulfate Hypotension 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Vincristine sulfate Ileus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vincristine sulfate Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vincristine sulfate Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Vincristine sulfate Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vincristine sulfate Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Vincristine sulfate Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vincristine sulfate Pain in jaw 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Vincristine sulfate Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Vincristine sulfate Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Vincristine sulfate Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Vincristine sulfate Respiratory distress 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Vincristine sulfate Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Vincristine sulfate Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Vincristine sulfate Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vincristine sulfate Tumour lysis syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Vinorelbine tartrate Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vinorelbine tartrate Agranulocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vinorelbine tartrate Anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vinorelbine tartrate Arrhythmia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vinorelbine tartrate Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vinorelbine tartrate Decreased appetite 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vinorelbine tartrate Diarrhoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vinorelbine tartrate Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vinorelbine tartrate Dyspnoea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vinorelbine tartrate Fatigue 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vinorelbine tartrate Febrile neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vinorelbine tartrate Headache 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vinorelbine tartrate Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vinorelbine tartrate Leukopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vinorelbine tartrate Mucosal inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vinorelbine tartrate Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vinorelbine tartrate Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vinorelbine tartrate Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vinorelbine tartrate Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vinorelbine tartrate Tachycardia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vinorelbine tartrate Thrombocytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vinorelbine tartrate Vomiting 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Vismodegib Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vismodegib Abdominal pain upper 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Vismodegib Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vismodegib Ageusia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Vismodegib Alanine aminotransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vismodegib Alopecia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vismodegib Anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vismodegib Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Vismodegib Aspartate aminotransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vismodegib Aspiration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vismodegib Asthenia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Vismodegib Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vismodegib Basal cell carcinoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vismodegib Blood creatinine increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vismodegib Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vismodegib Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vismodegib Bronchitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vismodegib Cardiac disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vismodegib Cardiac failure congestive 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vismodegib Cellulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vismodegib Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vismodegib Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vismodegib Constipation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Vismodegib Cough 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vismodegib Deafness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vismodegib Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vismodegib Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Vismodegib Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vismodegib Dementia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vismodegib Disease progression 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Vismodegib Dry mouth 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vismodegib Dysarthria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vismodegib Dysgeusia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vismodegib Dyspnoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Vismodegib Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Vismodegib Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Vismodegib Gamma-glutamyltransferase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vismodegib Gastric disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vismodegib Gastrointestinal haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vismodegib Haemoglobin decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vismodegib Haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vismodegib Hypercalcaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vismodegib Hyperkalaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vismodegib Hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vismodegib Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vismodegib Hyponatraemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vismodegib Ileus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vismodegib Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vismodegib Intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vismodegib Loss of consciousness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vismodegib Malaise 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vismodegib Malignant melanoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vismodegib Malnutrition 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vismodegib Muscle spasms 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Vismodegib Myocardial infarction 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Vismodegib Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Vismodegib Neutrophil count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vismodegib Pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vismodegib Platelet count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vismodegib Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Vismodegib Pulmonary embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vismodegib Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vismodegib Renal impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vismodegib Respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vismodegib Seizure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vismodegib Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vismodegib Squamous cell carcinoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vismodegib Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vismodegib Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vismodegib Weight increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vismodegib White blood cell count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vorapaxar sulfate Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Abdominal distension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Abdominal pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Abdominal pain upper 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Acute hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Acute kidney injury 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Acute myeloid leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Acute respiratory distress syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Agranulocytosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Altered state of consciousness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Anaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Arrhythmia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Aspartate aminotransferase increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Atrial fibrillation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Atrioventricular block complete 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Azotaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Voriconazole Back pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Voriconazole Bacterial infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Balance disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Voriconazole Basal cell carcinoma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Blindness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Voriconazole Blister 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Voriconazole Blood bilirubin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Voriconazole Blood creatine phosphokinase increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Voriconazole Blood creatinine increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Blood glucose increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Voriconazole Blood urea increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Body temperature increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Voriconazole Bone marrow failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Bone pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Voriconazole Bradycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Brain oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Candida infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Cardiac failure congestive 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Voriconazole Cerebral haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Cerebral infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Cerebrovascular accident 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Chest pain 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Chronic obstructive pulmonary disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Coma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Confusional state 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Congestive cardiomyopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Voriconazole Coordination abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Voriconazole Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Dehydration 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Voriconazole Diarrhoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Disorientation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Voriconazole Disseminated intravascular coagulation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Drug eruption 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Drug interaction 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Voriconazole Drug reaction with eosinophilia and systemic symptoms 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Drug resistance 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Dysphagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Dysphonia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Voriconazole Dyspnoea 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Voriconazole Ecchymosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Electrocardiogram QT prolonged 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Encephalopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Eosinophilia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Voriconazole Erythema 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Voriconazole Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Voriconazole Febrile neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Fungal infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Gastrointestinal disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Haematuria 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Voriconazole Haemolysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Haemoptysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Haemorrhage intracranial 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Hallucination 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Hallucination, visual 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Voriconazole Hepatic enzyme increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Hepatic function abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Hepatitis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Hepatitis acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Voriconazole Hepatocellular injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Hepatotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Voriconazole Herpes simplex 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Voriconazole Herpes zoster 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Voriconazole Hyperbilirubinaemia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Voriconazole Hyperglycaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Hyperkalaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Hypernatraemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Voriconazole Hypertension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Hypoaesthesia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Hypoglycaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Hypokalaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Hypomagnesaemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Hyponatraemia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Hypotension 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Hypothyroidism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Voriconazole Hypoxia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Ill-defined disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Immune system disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Voriconazole Inappropriate antidiuretic hormone secretion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Influenza like illness 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Voriconazole Interstitial lung disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Laboratory test abnormal 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Voriconazole Leukaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Leukocytosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Voriconazole Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Liver disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Liver function test abnormal 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Voriconazole Liver function test increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Loss of consciousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Lung disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Lung infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Lung infiltration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Malaise 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Voriconazole Memory impairment 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Meningitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Voriconazole Metastases to liver 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Voriconazole Nausea 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Necrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Neuropathy peripheral 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Voriconazole Neurotoxicity 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Neutropenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Oedema peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Voriconazole Pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Voriconazole Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Voriconazole Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Voriconazole Peripheral swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Voriconazole Photophobia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Voriconazole Platelet count decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Pneumocystis jirovecii pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Pneumonia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Pneumonia bacterial 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Pneumothorax 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Pyrexia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Voriconazole Rash erythematous 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Rash macular 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Voriconazole Rash maculo-papular 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Voriconazole Renal disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Renal impairment 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Respiratory disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Respiratory distress 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Rhabdomyolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Sepsis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Skin disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Voriconazole Stevens-Johnson syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Tachycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Thrombosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Torsade de pointes 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Toxic epidermal necrolysis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Toxic skin eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Voriconazole Treatment failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Urinary tract infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Ventricular fibrillation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Ventricular tachycardia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Viral infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Vision blurred 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Voriconazole Visual acuity reduced 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Voriconazole Visual field defect 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Voriconazole Vomiting 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Voriconazole Weight decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Voriconazole White blood cell count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vorinostat Acute kidney injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vorinostat Anaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Vorinostat Asthenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vorinostat Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vorinostat Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vorinostat Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vorinostat Decreased appetite 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vorinostat Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vorinostat Diarrhoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Vorinostat Disease progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vorinostat Dysgeusia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vorinostat Embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vorinostat Epistaxis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vorinostat Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vorinostat Febrile neutropenia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Vorinostat Hyperglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vorinostat Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vorinostat Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vorinostat Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vorinostat Nausea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Vorinostat Neutropenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vorinostat Neutrophil count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vorinostat Pancytopenia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vorinostat Platelet count decreased 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Vorinostat Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Vorinostat Pulmonary embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vorinostat Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Vorinostat Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Vorinostat Thrombocytopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vorinostat Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vorinostat Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vortioxetine Anger 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vortioxetine Cerebrovascular accident 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vortioxetine Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vortioxetine Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vortioxetine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vortioxetine Depressed mood 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vortioxetine Depression 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vortioxetine Dizziness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vortioxetine Drug abuse 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vortioxetine Fatigue 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vortioxetine Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vortioxetine Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vortioxetine Intentional self-injury 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vortioxetine Irritability 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vortioxetine Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Vortioxetine Somnolence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vortioxetine Suicidal ideation 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Vortioxetine Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vortioxetine Vomiting 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Vortioxetine Weight decreased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vortioxetine hydrobromide Abnormal dreams 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vortioxetine hydrobromide Anger 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Vortioxetine hydrobromide Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Vortioxetine hydrobromide Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Vortioxetine hydrobromide Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Vortioxetine hydrobromide Hypersensitivity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vortioxetine hydrobromide Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Vortioxetine hydrobromide Mania 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Vortioxetine hydrobromide Mood swings 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vortioxetine hydrobromide Nausea 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Vortioxetine hydrobromide Pruritus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Vortioxetine hydrobromide Serotonin syndrome 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Vortioxetine hydrobromide Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Vortioxetine hydrobromide Vomiting 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Voxelotor Abdominal pain upper 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Voxelotor Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Voxelotor Fatigue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Voxelotor Headache 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Voxelotor Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Voxelotor Pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Voxelotor Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Voxelotor Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Voxelotor Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Abdominal pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Warfarin Abdominal pain lower 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Abscess 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Acute kidney injury 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Warfarin Acute myocardial infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Acute respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Warfarin Agitation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Amnesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Anaemia 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Warfarin Anal incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Aphasia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Warfarin Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Warfarin Ascites 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Warfarin Asthenia 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Warfarin Ataxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Atelectasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Atrial fibrillation 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Warfarin Back pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Warfarin Balance disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Warfarin Blood albumin decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Warfarin Blood creatine phosphokinase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Blood creatinine increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Blood pressure decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Blood pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Blood urine present 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Warfarin Bradycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Warfarin Brain oedema 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin C-reactive protein increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Cardiac arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Warfarin Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Warfarin Cardiac failure acute 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Cardiac failure congestive 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Cardiac tamponade 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Warfarin Cardio-respiratory arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Warfarin Cardiogenic shock 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Cardiovascular disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Warfarin Cellulitis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Cerebral haemorrhage 1.0 1.0 1.0 0.0 0.0 1.0 0.0 Warfarin Cerebral infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Cerebrovascular accident 1.0 1.0 0.0 0.0 0.0 1.0 0.0 Warfarin Chest pain 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Warfarin Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Cholelithiasis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Chromaturia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Chronic kidney disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Chronic obstructive pulmonary disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Circulatory collapse 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Warfarin Clostridium difficile infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Coagulopathy 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Warfarin Colitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Warfarin Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Warfarin Confusional state 1.0 1.0 1.0 0.0 0.0 1.0 0.0 Warfarin Constipation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Contusion 0.0 0.0 0.0 0.0 0.0 1.0 1.0 Warfarin Coronary artery disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Cough 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Warfarin Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Warfarin Decreased appetite 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Warfarin Deep vein thrombosis 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Warfarin Dehydration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Delirium 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Warfarin Dementia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Depressed level of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Warfarin Dermatitis bullous 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Diarrhoea 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Warfarin Diarrhoea haemorrhagic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Disease progression 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Warfarin Disseminated intravascular coagulation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Warfarin Diverticulitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Dizziness 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Warfarin Dizziness postural 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Warfarin Duodenal ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Dysarthria 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Warfarin Dysgeusia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Dysphagia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Warfarin Dyspnoea 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Warfarin Dyspnoea exertional 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Ecchymosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Warfarin Embolism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Warfarin Encephalopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Epistaxis 0.0 0.0 1.0 0.0 0.0 1.0 0.0 Warfarin Eye haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Facial paralysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Warfarin Faeces discoloured 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Warfarin Fatigue 0.0 0.0 1.0 1.0 0.0 1.0 0.0 Warfarin Feeding disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Flank pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Fluid retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Gastric disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Gastric haemorrhage 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Warfarin Gastric ulcer 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Warfarin Gastritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Gastrointestinal disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Gastrointestinal haemorrhage 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Warfarin Gastrooesophageal reflux disease 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Gingival bleeding 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Gout 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Haematemesis 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Warfarin Haematochezia 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Warfarin Haematocrit decreased 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Warfarin Haematoma 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Warfarin Haematuria 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Warfarin Haemodynamic instability 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Warfarin Haemoglobin decreased 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Warfarin Haemoptysis 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Warfarin Haemorrhage 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Warfarin Haemorrhage intracranial 1.0 1.0 1.0 0.0 0.0 1.0 0.0 Warfarin Haemorrhagic stroke 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Warfarin Haemorrhoids 0.0 0.0 1.0 0.0 0.0 1.0 0.0 Warfarin Headache 1.0 1.0 0.0 0.0 0.0 1.0 0.0 Warfarin Heart rate increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Hemiparesis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Warfarin Hemiplegia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Warfarin Hepatic cirrhosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Hepatic failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Warfarin Hepatic function abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Hyperkalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Hypersensitivity vasculitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Hypertension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Warfarin Hyperthyroidism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Hypoaesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Hypoglycaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Hyponatraemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Hypophagia 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Warfarin Hypotension 1.0 1.0 1.0 0.0 0.0 1.0 0.0 Warfarin Hypovolaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Hypoxia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Warfarin Ileus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Intracranial pressure increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Warfarin Intraocular pressure increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Iron deficiency anaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Laceration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Lethargy 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Leukocytosis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Liver function test abnormal 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Warfarin Liver injury 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Warfarin Loss of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Warfarin Lower respiratory tract infection 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Warfarin Malaise 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Mass 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Melaena 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Warfarin Mental status changes 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Warfarin Metabolic acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Mitral valve incompetence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Mobility decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Movement disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Multiple organ dysfunction syndrome 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Warfarin Muscular weakness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Warfarin Myocardial infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Warfarin Myocardial ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Nausea 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Warfarin Necrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Warfarin Nephropathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Nervous system disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Warfarin Obstructive airways disorder 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Warfarin Oedema 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Oedema peripheral 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Oesophageal ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Oesophagitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Orthostatic hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Pain 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Pain in extremity 0.0 0.0 1.0 0.0 0.0 1.0 0.0 Warfarin Pallor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Paraesthesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Peptic ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Pericardial effusion 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Warfarin Peripheral ischaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Peripheral swelling 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Warfarin Petechiae 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Platelet count decreased 0.0 0.0 1.0 0.0 0.0 1.0 0.0 Warfarin Pleural effusion 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Warfarin Pneumonia 1.0 1.0 1.0 0.0 0.0 1.0 0.0 Warfarin Pneumonia aspiration 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Polyp 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Premature delivery 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Warfarin Presyncope 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Productive cough 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Proteinuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Prothrombin time prolonged 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Pulmonary alveolar haemorrhage 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Warfarin Pulmonary haemorrhage 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Pulmonary mass 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Warfarin Pyelonephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Pyrexia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Warfarin Rales 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Rectal haemorrhage 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Warfarin Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Warfarin Renal impairment 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Warfarin Respiratory depression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Warfarin Respiratory distress 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Warfarin Respiratory failure 1.0 1.0 0.0 0.0 0.0 1.0 0.0 Warfarin Retinal detachment 0.0 0.0 1.0 1.0 0.0 0.0 0.0 Warfarin Seizure 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Warfarin Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Warfarin Septic shock 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Warfarin Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Warfarin Shock haemorrhagic 1.0 1.0 1.0 0.0 0.0 1.0 0.0 Warfarin Skin exfoliation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Skin lesion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Skin necrosis 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Small intestinal obstruction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Somnolence 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Warfarin Speech disorder 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Warfarin Staphylococcal infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Subarachnoid haemorrhage 1.0 1.0 1.0 0.0 0.0 1.0 0.0 Warfarin Subdural haematoma 1.0 1.0 1.0 0.0 0.0 1.0 0.0 Warfarin Suicide attempt 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Swelling 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Syncope 0.0 1.0 1.0 1.0 0.0 1.0 0.0 Warfarin Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Warfarin Thrombocytopenia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Warfarin Thrombosis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Warfarin Toxic epidermal necrolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Transient ischaemic attack 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Warfarin Treatment failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Warfarin Tremor 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Troponin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Tubulointerstitial nephritis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Ulcer 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Unresponsive to stimuli 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Warfarin Upper gastrointestinal haemorrhage 0.0 1.0 1.0 0.0 0.0 1.0 0.0 Warfarin Urinary retention 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Urinary tract infection 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Warfarin Visual acuity reduced 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin Vomiting 1.0 1.0 1.0 0.0 0.0 1.0 0.0 Warfarin Weight decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin White blood cell count increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin sodium Abdominal distension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin sodium Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin sodium Chills 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin sodium Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Warfarin sodium Diarrhoea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin sodium Haemorrhage 0.0 1.0 0.0 0.0 0.0 1.0 0.0 Warfarin sodium Hypersensitivity 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin sodium Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Warfarin sodium Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Water Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zanamivir Loss of consciousness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zidovudine Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zidovudine Acute kidney injury 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zidovudine Anaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zidovudine Aspartate aminotransferase increased 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Zidovudine Atrial septal defect 0.0 0.0 0.0 0.0 1.0 0.0 0.0 Zidovudine Cardiac failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zidovudine Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zidovudine Drug interaction 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zidovudine Drug resistance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zidovudine Dysphagia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zidovudine Erythema 0.0 1.0 0.0 1.0 1.0 0.0 0.0 Zidovudine Maternal drugs affecting foetus 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Zidovudine Musculoskeletal discomfort 0.0 1.0 0.0 0.0 1.0 0.0 0.0 Zidovudine Nausea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zidovudine Neuropathy peripheral 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zidovudine Neutropenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zidovudine Premature baby 1.0 0.0 0.0 0.0 1.0 0.0 0.0 Zidovudine Premature delivery 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zidovudine Rhabdomyolysis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zidovudine Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zidovudine Treatment failure 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Ziprasidone Anxiety 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ziprasidone Blood creatine phosphokinase increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ziprasidone Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ziprasidone Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ziprasidone Muscular weakness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ziprasidone Neuroleptic malignant syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ziprasidone Pneumonia aspiration 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ziprasidone Respiratory failure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Ziprasidone Tremor 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Ziprasidone hydrochloride Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Ziprasidone hydrochloride Dyskinesia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Abasia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Abdominal distension 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Abdominal pain 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Abdominal pain lower 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Abdominal pain upper 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Abscess 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Acute kidney injury 1.0 1.0 1.0 1.0 0.0 0.0 0.0 Zoledronic acid Acute respiratory distress syndrome 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Acute respiratory failure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Alopecia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Altered state of consciousness 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Amnesia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Anaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Anal incontinence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zoledronic acid Anaphylactic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Aphasia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Aphthous ulcer 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Arthralgia 0.0 0.0 0.0 1.0 0.0 1.0 0.0 Zoledronic acid Arthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Arthropathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Asthenia 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Asthma 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Atelectasis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Atrial fibrillation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Back pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Bacterial infection 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Balance disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Blindness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Blister 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Blood glucose increased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Blood lactate dehydrogenase increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Blood potassium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zoledronic acid Blood pressure decreased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Blood pressure increased 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Zoledronic acid Blood sodium decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zoledronic acid Blood urea increased 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Blood urine present 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zoledronic acid Body temperature decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Body temperature increased 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Bone disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Bone pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Zoledronic acid Bradycardia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Breast cancer 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Breast pain 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Bronchitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Burning sensation 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Bursitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid C-reactive protein increased 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Zoledronic acid Cachexia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Candida infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Cardiac arrest 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Cardiac disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Cardiac failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Cardiac failure congestive 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Cardio-respiratory arrest 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Cataract 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Cellulitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Cerebral infarction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Cerebrovascular accident 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Chest discomfort 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Chest pain 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Chills 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Chromaturia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zoledronic acid Chronic obstructive pulmonary disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Clostridium difficile colitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Coagulopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Cognitive disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Cold sweat 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Colon cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Coma 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Confusional state 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Zoledronic acid Conjunctivitis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Constipation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Coronary artery disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Cough 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Cyst 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Deafness 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Zoledronic acid Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Decubitus ulcer 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Deep vein thrombosis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Dehydration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Delirium 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Dementia 1.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Dental caries 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Depressed level of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Depression 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Dermatitis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Diabetes mellitus 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Diarrhoea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Diplopia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Dizziness 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Zoledronic acid Drug hypersensitivity 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Drug intolerance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Drug resistance 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Dry mouth 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Dry skin 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Dry throat 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Dysaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Dysarthria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Dysgeusia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Dyspepsia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Dysphagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Dysphonia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Dyspnoea 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Dysstasia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Ear infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Eating disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Electrocardiogram QT prolonged 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zoledronic acid Electrolyte imbalance 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zoledronic acid Emotional distress 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Epistaxis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Eye disorder 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Eye haemorrhage 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Eye irritation 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Eye pain 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Zoledronic acid Eye swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Fear 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Feeding disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Feeling abnormal 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Feeling cold 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Femur fracture 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Flank pain 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Flatulence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Fungal infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Fungal skin infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Gastric cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Gastritis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Gastrointestinal disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Gastrointestinal haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Generalised tonic-clonic seizure 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Zoledronic acid Gingivitis 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Zoledronic acid Haematemesis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Haematoma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Haemoptysis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Haemorrhage 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zoledronic acid Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Heart rate increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Hemiparesis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Hemiplegia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Hepatic cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Hepatic failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Hepatotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Hydronephrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Hypercalcaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Hyperglycaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Hyperhidrosis 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Hyperkalaemia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Hypernatraemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Hyperpyrexia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Hypersensitivity 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Hypertension 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Hypertensive crisis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Hyperthermia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Hyperthyroidism 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Hyperventilation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zoledronic acid Hypoacusis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Hypoaesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Hypocalcaemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Zoledronic acid Hypoglycaemia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zoledronic acid Hypokinesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Hypomagnesaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zoledronic acid Hyponatraemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Zoledronic acid Hypophagia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Hypophosphataemia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Zoledronic acid Hypotension 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Hypothyroidism 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Hypoxia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Inappropriate antidiuretic hormone secretion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zoledronic acid Incontinence 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Inflammation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zoledronic acid Influenza like illness 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Interstitial lung disease 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Intestinal obstruction 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Intraocular pressure increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Jaundice 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Jaundice cholestatic 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Joint stiffness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Joint swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Lacrimation increased 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Large intestine perforation 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zoledronic acid Lethargy 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Leukopenia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Limb discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Liver disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Liver injury 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Local swelling 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Loss of consciousness 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Lung disorder 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Lung infection 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Lung infiltration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Lung neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Lymphadenopathy 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Lymphocyte count decreased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zoledronic acid Lymphoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Malaise 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Malignant neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Malnutrition 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Memory impairment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Mental disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Mental status changes 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Metabolic acidosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Zoledronic acid Metastases to central nervous system 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Metastases to liver 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Metastases to lung 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Metastatic neoplasm 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Mobility decreased 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Mouth ulceration 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Movement disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Multiple fractures 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Multiple organ dysfunction syndrome 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Muscle rigidity 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Muscle spasms 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Muscular weakness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Musculoskeletal chest pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Musculoskeletal discomfort 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Musculoskeletal disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Musculoskeletal pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Musculoskeletal stiffness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Myalgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Myocardial infarction 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Nausea 0.0 1.0 0.0 1.0 0.0 1.0 0.0 Zoledronic acid Neck pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Necrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Neoplasm malignant 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Neoplasm progression 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Nephrolithiasis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Nephropathy toxic 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Nephrotic syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zoledronic acid Nervousness 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Neuralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Neuropathy peripheral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Neurotoxicity 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Neutropenia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Neutrophil count decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Night sweats 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Nodule 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Ocular hyperaemia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Zoledronic acid Oedema 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Oedema peripheral 1.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Oesophagitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Oral disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Oral pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Osteomyelitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Osteonecrosis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Osteonecrosis of jaw 0.0 0.0 0.0 1.0 0.0 1.0 1.0 Zoledronic acid Osteoporosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Oxygen saturation decreased 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Pain 0.0 1.0 0.0 1.0 0.0 1.0 1.0 Zoledronic acid Pain in extremity 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Zoledronic acid Pain in jaw 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Zoledronic acid Pallor 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Palpitations 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Pancreatitis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zoledronic acid Pancytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Paraesthesia oral 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Paralysis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Pelvic pain 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Pericarditis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Peripheral coldness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Peripheral swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Photophobia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Plasma cell myeloma 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Pleural effusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Pneumonia 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Pneumothorax 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Pollakiuria 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Prostate cancer 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Proteinuria 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Pruritus 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Psychotic disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Pulmonary embolism 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Pulmonary fibrosis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Pulmonary mass 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Pulmonary oedema 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Pyelonephritis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Pyrexia 0.0 1.0 1.0 1.0 0.0 0.0 0.0 Zoledronic acid Rash 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Rash generalised 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Red blood cell sedimentation rate increased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Renal disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Renal failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Renal tubular necrosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Zoledronic acid Respiratory disorder 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Respiratory distress 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Respiratory failure 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Retching 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Retinal detachment 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Rhabdomyolysis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zoledronic acid Rheumatoid arthritis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Rhinorrhoea 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Seizure 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Sensory loss 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Sepsis 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Septic shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Shock 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Sinus tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Sinusitis 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Skin disorder 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Skin reaction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zoledronic acid Skin ulcer 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Sleep disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Somnolence 1.0 1.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Speech disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Spinal compression fracture 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Spinal fracture 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Zoledronic acid Stomatitis 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Stress 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Stress cardiomyopathy 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Sudden death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Swelling 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Swelling face 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Swollen tongue 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zoledronic acid Tachycardia 1.0 1.0 1.0 0.0 0.0 0.0 0.0 Zoledronic acid Tachypnoea 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Zoledronic acid Tenderness 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Thirst 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Thrombocytopenia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Tooth abscess 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Tooth disorder 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Zoledronic acid Toothache 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Zoledronic acid Transient ischaemic attack 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Tremor 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Troponin increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zoledronic acid Tubulointerstitial nephritis 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Upper limb fracture 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Zoledronic acid Urinary incontinence 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Urine output decreased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Urticaria 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Vasodilatation 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zoledronic acid Ventricular fibrillation 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Vision blurred 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Visual impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zoledronic acid Vomiting 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Zoledronic acid Weight decreased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid Wheezing 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zoledronic acid White blood cell count increased 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zolmitriptan Colitis ischaemic 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zolmitriptan Dizziness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zolmitriptan Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zolmitriptan Hyperhidrosis 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zolmitriptan Myalgia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zolmitriptan Myocardial infarction 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zolmitriptan Palpitations 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zolmitriptan Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zolmitriptan Stress cardiomyopathy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zolpidem tartrate Abdominal pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zolpidem tartrate Acute kidney injury 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Zolpidem tartrate Aggression 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zolpidem tartrate Alanine aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zolpidem tartrate Amnesia 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Zolpidem tartrate Anxiety 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zolpidem tartrate Arrhythmia 1.0 1.0 0.0 0.0 0.0 0.0 0.0 Zolpidem tartrate Arthralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zolpidem tartrate Aspartate aminotransferase increased 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zolpidem tartrate Asthenia 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Zolpidem tartrate Balance disorder 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Zolpidem tartrate Cognitive disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zolpidem tartrate Confusional state 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zolpidem tartrate Decreased appetite 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zolpidem tartrate Delusion 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zolpidem tartrate Depressed mood 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zolpidem tartrate Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Zolpidem tartrate Disorientation 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zolpidem tartrate Disturbance in attention 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zolpidem tartrate Dyspepsia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zolpidem tartrate Dysuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zolpidem tartrate Fatigue 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zolpidem tartrate Feeling abnormal 0.0 1.0 0.0 0.0 0.0 0.0 1.0 Zolpidem tartrate Gait disturbance 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zolpidem tartrate Glaucoma 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zolpidem tartrate Hallucination 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zolpidem tartrate Headache 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zolpidem tartrate Hyperhidrosis 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Zolpidem tartrate Hypokinesia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zolpidem tartrate Hypotension 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Zolpidem tartrate Hypoxia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zolpidem tartrate Influenza like illness 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zolpidem tartrate Insomnia 0.0 0.0 0.0 1.0 0.0 0.0 1.0 Zolpidem tartrate Lethargy 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zolpidem tartrate Malaise 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zolpidem tartrate Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zolpidem tartrate Muscle spasms 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zolpidem tartrate Muscular weakness 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Zolpidem tartrate Nausea 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zolpidem tartrate Neuralgia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zolpidem tartrate Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zolpidem tartrate Pulmonary embolism 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zolpidem tartrate Pulmonary oedema 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zolpidem tartrate Sleep disorder 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zolpidem tartrate Somnolence 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Zolpidem tartrate Suicide attempt 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zolpidem tartrate Syncope 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zolpidem tartrate Tachycardia 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Zolpidem tartrate Thinking abnormal 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Zolpidem tartrate Tinnitus 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zolpidem tartrate Tremor 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zolpidem tartrate Ventricular tachycardia 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zolpidem tartrate Vomiting 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zolpidem tartrate Weight decreased 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Zonisamide Abortion spontaneous 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zonisamide Acute respiratory failure 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zonisamide Ataxia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zonisamide Chest pain 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zonisamide Coma 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zonisamide Completed suicide 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zonisamide Death 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zonisamide Delusion 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zonisamide Depression 0.0 1.0 0.0 1.0 0.0 0.0 0.0 Zonisamide Diplopia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zonisamide Dizziness 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zonisamide Drug eruption 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zonisamide Drug reaction with eosinophilia and systemic symptoms 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zonisamide Dysphagia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zonisamide Electrocardiogram QT prolonged 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zonisamide Epilepsy 0.0 0.0 0.0 1.0 1.0 0.0 0.0 Zonisamide Fatigue 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zonisamide Fracture 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zonisamide Hallucination 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zonisamide Hepatic function abnormal 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zonisamide Hypokalaemia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zonisamide Hypotension 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zonisamide Insomnia 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zonisamide Memory impairment 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zonisamide Metabolic acidosis 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zonisamide Nausea 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zonisamide Neuroleptic malignant syndrome 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zonisamide Nystagmus 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zonisamide Paraesthesia 0.0 0.0 0.0 1.0 0.0 0.0 0.0 Zonisamide Pneumonia 1.0 0.0 1.0 0.0 0.0 0.0 0.0 Zonisamide Pneumonia aspiration 1.0 0.0 0.0 0.0 0.0 0.0 0.0 Zonisamide Pollakiuria 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zonisamide Psychotic disorder 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zonisamide Pyrexia 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zonisamide Rash 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zonisamide Seizure 0.0 1.0 0.0 0.0 0.0 0.0 0.0 Zonisamide Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zonisamide Stevens-Johnson syndrome 0.0 1.0 1.0 0.0 0.0 0.0 0.0 Zonisamide Suicide attempt 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zonisamide Treatment failure 0.0 0.0 0.0 0.0 0.0 0.0 1.0 Zonisamide Urinary tract infection 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zonisamide Vomiting 0.0 0.0 1.0 0.0 0.0 0.0 0.0 Zopiclone Somnolence 0.0 0.0 1.0 0.0 0.0 0.0 0.0