,CGC,IntOGen,BertVogelstein125,SMG127,Comprehensive435 EPHB2,-,LUAD,-,-,- FCGR2B,ALL,-,-,-,- NUMA1,APL,-,-,-,High Confidence Driver GRIN2A,"melanoma, colorectal carcinoma, gastric carcinoma, lung carcinoma",-,-,-,- UTP14A,-,-,-,-,Candidate driver ATF7IP,-,-,-,-,Candidate driver BAZ2B,-,"CM,HNSC,LUAD,OV,SCLC,UCEC",-,-,- MAST2,-,-,-,-,High Confidence Driver NIN,MPN,-,-,-,High Confidence Driver MME,-,-,-,-,Candidate driver BCORL1,"AML, HNSCC",-,-,-,- NONO,papillary renal,-,-,-,High Confidence Driver CHD3,-,"BLCA,CM,LUSC,PRAD,STAD,THCA,UCEC",-,-,Candidate driver LAMA2,-,HNSC,-,-,- MYCBP2,-,-,-,-,Candidate driver HUWE1,-,-,-,-,High Confidence Driver JAK3,"acute megakaryocytic leukaemia, ETP ALL",-,Oncogene,-,- CAT,-,"BLCA,CM,HNSC,LUAD,PRAD,RCCC,STAD,UCEC",-,-,- ATG13,-,-,-,-,High Confidence Driver ANK3,-,"BLCA,BRCA,CLL,CM,GBM,NB,PAAD,SCLC,STAD,UCEC",-,-,- IKBKB,SMZL,-,-,-,- EPPK1,-,-,-,1.40%,Candidate driver BARD1,breast cancer,-,-,-,High Confidence Driver ANKRD6,-,-,-,-,Candidate driver FN1,-,"BLCA,BRCA,CM,COREAD,GBM,HNSC,LUAD,LUSC,PRAD,SCLC",-,-,High Confidence Driver MAP4K1,-,LUAD,-,-,- KIAA1549,pilocytic astrocytoma,-,-,-,- TRIM33,papillary thyroid,-,-,-,- RAD17,"lymphoma, colon cancer",-,-,-,- ANXA6,-,-,-,-,Candidate driver MAP4K3,-,"BLCA,CM,GBM,HNSC,LUAD,OV",-,-,- GTF2H1,-,-,-,-,High Confidence Driver PGR,-,UCEC,-,-,- HIP1,"CMML, NSCLC",-,-,-,- UBE4A,-,-,-,-,Candidate driver AQR,-,"BLCA,BRCA,CM,GBM,LUSC,PRAD,STAD",-,-,- PRPF8,-,"AML,GBM,HNSC,LUAD,LUSC,PRAD,THCA,UCEC",-,-,High Confidence Driver GPSM2,-,"HNSC,LUAD,LUSC,UCEC",-,-,- HMGXB4,-,-,-,-,High Confidence Driver AHCYL2,-,-,-,-,Candidate driver ABCB1,-,-,-,-,High Confidence Driver ICE1,-,-,-,-,Candidate driver FAT2,-,HNSC,-,-,- BIRC6,"melanoma, gastric adenocarcinoma, lung adenocarcinoma",-,-,-,- PTPRD,"lung cancer, kidney cancer, HNSCC, glioblastoma",-,-,-,- CBL,"AML, JMML, MDS",-,Oncogene,-,- ZEB2,-,-,-,-,Candidate driver BRCA1,ovarian,"BLCA,BRCA,CM,GBM,HNSC,OV,STAD,UCEC",TSG,1.90%,High Confidence Driver DST,-,-,-,-,Candidate driver ARFGAP3,-,PRAD,-,-,- HERC1,-,-,-,-,Candidate driver ROS1,"glioblastoma, NSCLC, Spitzoid tumour, cholangiocarcinoma, borderline ovarian",-,-,-,- ATRX,"pancreatic neuroendocrine tumours, paediatric GBM","CM,COREAD,ESCA,GBM,HC,HNSC,LGG,NB,OV,PRAD,SCLC,STAD",TSG,2.80%,High Confidence Driver MED12,"uterine leiomyoma, fibroadenoma, phyllodes tumour","AML,BLCA,BRCA,CLL,COREAD,ESCA,OV,PRAD,SCLC,STAD",Oncogene,-,High Confidence Driver BIRC3,"CLL, MALT, MCL, MM",-,-,-,- LEPR,-,-,-,-,High Confidence Driver CDC73,parathyroid adenoma,"CM,COREAD,LUSC,RCCC,STAD",TSG,-,High Confidence Driver ARHGEF12,AML,-,-,-,- LRPPRC,-,CM,-,-,- PABPC1,"HNSCC, biliary tract carcinoma",RCCC,-,-,High Confidence Driver CAD,-,"BLCA,BRCA,COREAD,GBM,HNSC,LGG,RCCC,STAD",-,-,- ZEB1,"CCRCC, melanoma",-,-,-,- SDHD,,-,-,-,- SGK1,Nodular lymphocyte predominant Hodgkin lymphoma,-,-,-,High Confidence Driver FAT1,"oral squamous cell, chemorefractory CLL, head and neck, pancreatic acinar cell carcinoma","BLCA,GBM,HNSC,LGG,LUAD,PRAD,SCLC",-,-,- FBN2,-,-,-,-,High Confidence Driver WASF3,-,CM,-,-,- PCM1,"papillary thyroid, CML, MPN",-,-,-,- SPEN,"SMZL, adenoid cystic carcinoma, DLBCL",-,-,-,High Confidence Driver NEB,-,-,-,-,High Confidence Driver MLLT10,AL,-,-,-,High Confidence Driver TET2,MDS,AML,TSG,1.60%,High Confidence Driver IREB2,-,"BLCA,CM,ESCA,HNSC,LUAD,LUSC,STAD,UCEC",-,-,- ARNTL,-,"BRCA,COREAD,ESCA,LUSC,UCEC",-,-,- KMT2D,"medulloblastoma, renal",-,-,-,- ABI1,AML,-,-,-,- PTPN13,"lung, NSCLC, gastric, peritoneal carcinomatosis",-,-,-,Candidate driver DROSHA,"Wilms tumour, NSCLC, bladder carcinoma",-,-,-,- CYSLTR2,uveal melanoma,-,-,-,- MAP3K4,-,"BLCA,CM,COREAD,ESCA,GBM,LUAD,LUSC,OV",-,-,High Confidence Driver PDS5A,-,-,-,-,Candidate driver SPOP,"prostate, endometrial","CM,HNSC,PRAD,STAD,UCEC",Oncogene,0.70%,High Confidence Driver IRF6,-,HNSC,-,-,- SIN3A,-,"GBM,HNSC,LUAD,LUSC,OV,RCCC,SCLC,STAD",-,1.10%,High Confidence Driver PIK3CA,"colorectal, gastric, glioblastoma, breast","BRCA,CM,COREAD,ESCA,GBM,HC,HNSC,LGG,LUSC,MB,MM,NB,OV,SCLC,STAD,THCA,UCEC",Oncogene,17.80%,High Confidence Driver TJP1,-,"GBM,LGG,OV,PRAD,RCCC,SCLC,STAD,THCA",-,-,- PSIP1,AML,HNSC,-,-,- CSF1R,"MDS, CML, AML, hemangioblastoma, CCRCC",-,Oncogene,-,- MAP3K1,luminal A breast,"BLCA,BRCA,CM,HNSC,LUAD,LUSC,STAD,UCEC",TSG,2.70%,High Confidence Driver CTCF,"endometrial, breast, head and neck cancer","BLCA,BRCA,CM,COREAD,HNSC,LUAD,RCCC,UCEC",-,2.40%,High Confidence Driver NUP98,AML,"BLCA,BRCA,CM,COREAD,ESCA,LUAD,LUSC,PRAD,RCCC,STAD",-,-,High Confidence Driver CUL2,-,"BLCA,CM,LUAD,OV,PRAD,STAD",-,-,- VAV1,T-cell lymphoma,-,-,-,- PTPRT,"HNSCC, colorectal cancer, gastric cancer, lung cancer, melanoma",-,-,-,- ARFGEF1,-,STAD,-,-,- HDAC9,-,"CM,GBM,RCCC",-,-,- PCSK5,-,STAD,-,-,- APC,"colorectal, pancreatic, desmoid, hepatoblastoma, glioma, other CNS","BLCA,BRCA,COREAD,HC,HNSC,MM,NSCLC,PRAD,STAD",TSG,7.30%,High Confidence Driver MGA,-,"BLCA,BRCA,COREAD,ESCA,HNSC,LUAD,MB,RCCC,UCEC",-,-,- PTCH1,"skin basal cell, medulloblastoma",MB,TSG,-,- KIAA1109,-,-,-,-,High Confidence Driver FAT4,"lymphoma, pancreatic, head and neck, melanoma, hepatocellular carcinoma",-,-,-,- SMARCAD1,-,-,-,-,Candidate driver ARID4B,-,BRCA,-,-,- ATR,"endometrial, gastric, epithelial ovarian, myeloma","BLCA,BRCA,ESCA,HNSC,OV,SCLC,STAD,UCEC",-,-,- PDGFRA,"GIST, idiopathic hypereosinophilic syndrome, paediatric glioblastoma",-,Oncogene,1.90%,High Confidence Driver ASXL2,"melanoma, CCRCC, AML",-,-,-,- KMT2C,medulloblastoma,-,TSG,6.60%,High Confidence Driver IL6ST,hepatocellular carcinoma,-,-,-,- BRIP1,,-,-,-,- ATM,T-PLL,"BRCA,CLL,COREAD,ESCA,HNSC,NB,PAAD,PRAD,RCCC,UCEC",TSG,3.30%,High Confidence Driver ESR1,breast,-,-,-,High Confidence Driver CHD8,-,GBM,-,-,High Confidence Driver N4BP2,lung cancer,-,-,-,- UBR5,"mantle cell lymphoma, gastric, colorectal",-,-,-,- LDHA,-,"CM,LUAD,THCA",-,-,- BCL6,"NHL, CLL",-,-,-,- IL2,intestinal T-cell lymphoma,-,-,-,- ZNF292,-,LGG,-,-,- AHNAK,-,"BLCA,BRCA,CM,PAAD,PRAD,SCLC,THCA",-,-,Candidate driver FOXP1,ALL,"BRCA,CM,COREAD,HNSC,LUSC,STAD",-,-,- BRWD1,-,"CM,COREAD,HNSC,LUAD,SCLC",-,-,- CNOT1,-,"ALL,BLCA,COREAD,ESCA,GBM,HC,PRAD,STAD",-,-,Candidate driver RTN4,-,"CM,COREAD,ESCA,HC,LUAD,LUSC,STAD,UCEC",-,-,- SEC24D,-,"BRCA,CM,HNSC,LUSC,NSCLC,RCCC",-,-,- NAV1,-,-,-,-,Candidate driver IKZF1,"ALL, DLBCL",-,-,-,- TGOLN2,-,-,-,-,Candidate driver SRCAP,-,-,-,-,Candidate driver PHOX2B,neuroblastoma,-,-,-,- ELF4,AML,HNSC,-,-,- EIF4G3,-,CM,-,-,- TNKS1BP1,-,-,-,-,Candidate driver CHD6,-,CM,-,-,- ITSN1,-,"BRCA,CM,COREAD,ESCA,HC,LUSC,OV,RCCC,SCLC",-,-,- FAT3,"SCC, colon adenocarcinoma, gastric adenocarcinoma",-,-,-,- RBM10,lung adenocarcinoma,"COREAD,ESCA,LUAD,LUSC",-,-,Candidate driver CUL3,lung cancer,"CM,ESCA,HNSC,LUAD,PRAD,STAD",-,-,Candidate driver BTK,"CLL, mantle cell lymphoma, WM",-,-,-,- SETX,-,-,-,-,Candidate driver NUP214,"AML, T-ALL",-,-,-,High Confidence Driver SPTAN1,-,"BRCA,ESCA,GBM,HNSC,LUSC,SCLC",-,-,Candidate driver G3BP1,-,LUAD,-,-,Candidate driver MEGF6,-,-,-,-,Candidate driver IRS2,-,"BLCA,ESCA,HNSC,LUAD,LUSC,PRAD,STAD",-,-,High Confidence Driver IARS2,-,-,-,-,Candidate driver FAM135B,SCLC,-,-,-,- NUTM1,lethal midline carcinoma,-,-,-,- TTK,-,-,-,-,Candidate driver CLSPN,-,"BLCA,BRCA,CLL,CM,COREAD,HNSC,LUAD,OV,SCLC",-,-,- FANCE,,-,-,-,- JAZF1,endometrial stromal tumour,-,-,-,- AJUBA,-,-,-,0.80%,High Confidence Driver MLH3,-,UCEC,-,-,- ASH1L,-,"BRCA,HC,OV,RCCC,SCLC,STAD",-,-,- MACF1,-,"BRCA,ESCA,HC,HNSC,NB,STAD",-,-,Candidate driver NBN,,-,-,-,- SALL4,"colorectal cancer, breast cancer, prostate cancer, glioblastoma, melanoma",-,-,-,- ARAP3,-,UCEC,-,-,- ITK,peripheral T-cell lymphoma,-,-,-,- CTNNB1,"colorectal, ovarian, hepatoblastoma, pleomorphic salivary gland adenoma, other tumour types","BLCA,CM,COREAD,ESCA,HC,HNSC,LUAD,LUSC,MB,OV,PRAD,STAD,THCA,UCEC",Oncogene,2.90%,High Confidence Driver PIK3CB,"SCC, NSCLC","BLCA,BRCA,CM,GBM,LUSC,NB,PRAD,STAD",-,-,High Confidence Driver CHD4,uterine serous carcinoma,"AML,BRCA,COREAD,DLBC,ESCA,OV,PRAD,UCEC",-,-,High Confidence Driver KDM6A,"renal cell carcinoma, bladder carcinoma, oesophageal SCC, MM, medulloblastoma, T-ALL, other tumour types","AML,BLCA,CLL,CM,ESCA,GBM,HNSC,LUAD,MB,PRAD,RCCC,SCLC,STAD,UCEC",TSG,2.00%,High Confidence Driver RANBP3,-,-,-,-,High Confidence Driver MCM3,-,CM,-,-,- COL18A1,-,-,-,-,High Confidence Driver ETNK1,"aCML, CMML, SM-AHD, HES",-,-,-,- SPEG,-,-,-,-,Candidate driver ANKRD11,-,-,-,-,Candidate driver EPHA3,"lung cancer, CRC, melanoma",-,-,2.10%,Candidate driver SMO,skin basal cell,MB,-,-,- KDM5A,AML,-,-,-,- TPR,"papillary thyroid, NSCLC",-,-,-,High Confidence Driver TANC2,-,-,-,-,Candidate driver ARID4A,-,STAD,-,-,- NFE2L2,"NSCLC, HNSCC","BLCA,CM,ESCA,HC,HNSC,LUAD,LUSC,RCCC,STAD,UCEC",Oncogene,2.30%,High Confidence Driver WNK1,-,CM,-,-,- SRGAP1,-,BRCA,-,-,- DDB2,,-,-,-,- STAG2,"bladder carcinoma, glioblastoma, melanoma, Ewing's sarcoma, myeloid neoplasms","AML,BLCA,BRCA,CLL,CM,COREAD,GBM,HNSC,OV",TSG,2.20%,High Confidence Driver ZMYM2,-,"BLCA,CM,LGG,LUAD,STAD,UCEC",-,-,High Confidence Driver PPFIBP1,"Spitzoid tumour, inflammatory myofibroblastic tumour",-,-,-,- CREB1,"clear cell sarcoma, angiomatoid fibrous histiocytoma",-,-,-,High Confidence Driver PSMD11,-,LUAD,-,-,Candidate driver BRCA2,"breast, ovarian, pancreatic","BRCA,OV",TSG,2.70%,High Confidence Driver CSF3R,"aCML, CNL, leukaemia lymphoma and MDS associated with severe congenital neutropenia, CMML, de novo AML, MDS",-,-,-,- PBRM1,"clear cell renal carcinoma, breast","BRCA,CLL,GBM,HC,HNSC,LUAD,NB,PAAD,RCCC",TSG,5.40%,High Confidence Driver RPN1,AML,-,-,-,- ARHGEF10L,lymphoma,-,-,-,- SMYD4,-,-,-,-,Candidate driver MED13,-,-,-,-,High Confidence Driver CAST,-,"BLCA,BRCA,CM,LUSC,UCEC",-,-,- BAP1,"uveal melanoma, breast, NSCLC, RCC","BLCA,BRCA,CM,ESCA,GBM,HNSC,LUAD,OV,RCCC,STAD",-,-,- CNOT3,T-ALL,"ALL,BRCA,CLL,CM,ESCA,LUAD,LUSC,PRAD,RCCC",-,-,Candidate driver PRKAR1A,papillary thyroid,"BRCA,MB",-,-,High Confidence Driver SS18,synovial sarcoma,-,-,-,- ABL1,"CML, ALL, T-ALL",-,Oncogene,-,High Confidence Driver AARS,-,-,-,-,Candidate driver TRRAP,melanoma,-,-,-,- ACTG2,-,"CM,LUAD,LUSC,STAD",-,-,- KDM5C,clear cell renal carcinoma,"BRCA,CM,GBM,HNSC,LUSC,RCCC",TSG,2.00%,High Confidence Driver MYC,"Burkitt lymphoma, amplified in other cancers, B-CLL",DLBC,-,-,- MKI67,-,-,-,-,Candidate driver ZFHX3,"endometrial, gastric, prostate","PRAD,UCEC",-,-,High Confidence Driver CUL1,-,"AML,BRCA,CM,COREAD,GBM,HNSC,LUSC,RCCC,STAD,UCEC",-,-,High Confidence Driver ARID1B,"breast, hepatocellular carcinoma","BLCA,CM,HC,HNSC,LGG,LUSC,MB,PRAD,RCCC,SCLC,STAD",TSG,-,- EPHA7,"CRC, melanoma",-,-,-,- PRKCD,-,-,-,-,High Confidence Driver INPPL1,-,UCEC,-,-,- MAP3K3,-,-,-,-,High Confidence Driver COBLL1,-,-,-,-,Candidate driver ACACA,-,UCEC,-,-,- AKAP9,papillary thyroid,"BRCA,COREAD,DLBC,GBM,NSCLC,PRAD,SCLC,STAD,THCA",-,-,High Confidence Driver NCOR1,breast,"BRCA,CLL,CM,GBM,HNSC,LGG,RCCC,UCEC",TSG,2.20%,High Confidence Driver GLI1,"CRC, oesophagus cancer",-,-,-,- REL,Hodgkin lymphoma,-,-,-,- CD209,prostate carcinoma,-,-,-,- BMPR1A,,-,-,-,- ASPM,-,"BRCA,CM,COREAD,ESCA,OV,SCLC",-,-,High Confidence Driver BMP5,melanoma,-,-,-,- RASGRP1,-,HNSC,-,-,- MSH2,"colorectal, endometrial, ovarian",-,TSG,-,- ZMYND8,-,-,-,-,Candidate driver KLK2,prostate,-,-,-,- EIF4G1,-,"BLCA,BRCA,CM,ESCA,LUAD,PRAD,RCCC,STAD,UCEC",-,-,- EP300,"colorectal, breast, pancreatic, AML, ALL, DLBCL","BLCA,BRCA,CLL,CM,ESCA,HNSC,LUAD,PAAD,PRAD,SCLC,UCEC",TSG,2.50%,High Confidence Driver ZNF638,-,CM,-,-,- KDR,"NSCLC, angiosarcoma","GBM,LUAD",-,-,- AFF4,ALL,"BLCA,BRCA,CM,ESCA,LUAD,LUSC,OV,STAD",-,-,- NRG1,NSCLC,-,-,-,- CREBBP,"ALL, AML, DLBCL, B-NHL","CLL,COREAD,DLBC,ESCA,LUAD,MB,NB,PAAD,SCLC",TSG,-,- SSX2IP,-,-,-,-,Candidate driver PREX2,"melanoma, pancreatic ductal adenocarcinoma",-,-,-,- ACVR1,DIPG,-,-,-,- IRF2,-,"CLL,STAD",-,-,- DHX15,-,"BRCA,CM,LUAD,LUSC,RCCC,STAD,UCEC",-,-,- XRN1,-,CM,-,-,- MET,"papillary renal, head-neck squamous cell","BLCA,ESCA,GBM,LGG,LUAD,LUSC,NB,RCCC,STAD,UCEC",Oncogene,-,- NOTCH2,"marginal zone lymphoma, DLBCL, bladder","BRCA,HNSC,PRAD",TSG,-,- PPP2R5A,-,"CM,LUAD,UCEC",-,-,- LEF1,"B-ALL, T-ALL, eyelid sebaceous carcinoma, AML, lymphomas",-,-,-,- GRM3,"melanoma, oral SCC",-,-,-,- PTEN,"glioma, prostate, endometrial","ALL,BLCA,BRCA,CM,COREAD,GBM,HC,LGG,LUAD,LUSC,OV,PRAD,RCCC,SCLC,STAD,THCA,UCEC",TSG,9.70%,High Confidence Driver ARID1A,"clear cell ovarian carcinoma, RCC, breast","BLCA,BRCA,CLL,COREAD,DLBC,ESCA,GBM,HC,LGG,LUAD,LUSC,MB,NB,OV,PAAD,RCCC,SCLC,STAD,UCEC",TSG,5.40%,High Confidence Driver MCM7,-,-,-,-,Candidate driver ATP2B3,adrenal aldosterone producing adenoma,-,-,-,- PTPRU,-,"BLCA,BRCA,COREAD,ESCA,SCLC,STAD",-,-,- TNFAIP3,"marginal zone B-cell lymphomas, Hodgkin lymphoma, PMBL",-,TSG,-,- SMCHD1,-,-,-,-,Candidate driver MYO5A,Spitzoid tumour,-,-,-,- TRIO,-,"BLCA,BRCA,COREAD,ESCA,GBM,HNSC,LGG,NB,OV,PRAD,RCCC,THCA",-,-,High Confidence Driver CHD1L,-,"CM,LUAD,LUSC,OV,PRAD,SCLC,STAD",-,-,- SS18L1,synovial sarcoma,-,-,-,- HOXC13,AML,-,-,-,- SH3PXD2A,-,-,-,-,Candidate driver LTBP1,-,-,-,-,Candidate driver COL1A1,"DFSP, aneurysmal bone cyst","CM,HNSC,LUAD,NB,STAD",-,-,- ERCC4,,-,-,-,- ZNF331,follicular thyroid adenoma,-,-,-,- ATP1A1,adrenal aldosterone producing adenoma,-,-,-,- HGF,-,"ESCA,LGG,NSCLC,OV,PRAD,SCLC,UCEC",-,-,- LRP6,-,"BRCA,CM,ESCA,GBM,NB,RCCC",-,-,- LEPROTL1,"lung cancer, colon cancer",-,-,-,- TCF4,-,"CM,HNSC,LUAD,MB,STAD",-,-,- NUP107,-,"BLCA,BRCA,CM,COREAD,ESCA,GBM,HNSC,LUAD,LUSC,SCLC,STAD",-,-,- STARD13,-,STAD,-,-,- MICAL1,-,-,-,-,Candidate driver KIF20B,-,-,-,-,Candidate driver USP9X,-,-,-,2.10%,Candidate driver SFPQ,papillary renal,"BLCA,BRCA,CM,LUAD",-,-,- SPECC1,JMML,-,-,-,- DNMT1,-,-,Oncogene,-,- KAT6B,"AML, leiomyoma",LGG,-,-,- RHOA,"diffuse gastric, T cell lymphomas, paediatric Burkitt lymphoma","BLCA,CM,ESCA,HNSC,OV,STAD",-,-,High Confidence Driver SYNE1,-,-,-,-,High Confidence Driver POLE,"colorectal carcinoma, endometrioid carcinoma, stomach carcinoma, skin cancer",-,-,-,Candidate driver MAF,MM,-,-,-,- MED24,-,"BLCA,BRCA,CM,COREAD,LUAD,LUSC,RCCC",-,-,- EPHA2,-,HNSC,-,-,- JAK2,"ALL, AML, MPN, CML",-,Oncogene,-,High Confidence Driver TRERF1,-,CM,-,-,- ARID5B,-,UCEC,-,1.60%,High Confidence Driver ITGA9,-,CM,-,-,- WNK2,gastric cancer,-,-,-,- EXT1,,-,-,-,- LUM,-,-,-,-,High Confidence Driver NFKB2,B-NHL,-,-,-,- RALGAPA1,-,-,-,-,Candidate driver MLF1,AML,-,-,-,- ZNF429,GBM,-,-,-,- KALRN,-,"BRCA,ESCA,GBM,HNSC,NSCLC,SCLC",-,-,High Confidence Driver NCKIPSD,ALL,-,-,-,- ELN,B-ALL,-,-,-,- DOCK2,-,-,-,-,High Confidence Driver NPM1,"NHL, APL, AML","AML,CM,LUAD",TSG,1.80%,High Confidence Driver METTL14,-,-,-,-,High Confidence Driver ARHGAP26,"AML, MDS","BLCA,CM,ESCA,LGG,LUAD,RCCC,STAD,THCA",-,-,- PIP5K1A,-,"BLCA,BRCA,CM,LUAD,LUSC,RCCC,STAD",-,-,High Confidence Driver PWWP2A,Spitzoid tumour,-,-,-,- BCL11B,T-ALL,-,-,-,- CDK12,serous ovarian,"BLCA,BRCA,COREAD,HNSC,LGG,LUAD,OV,SCLC,THCA",-,1.50%,High Confidence Driver CACNA1D,adrenal aldosterone producing adenoma,-,-,-,- SPRR3,-,LUAD,-,-,- CLASP2,-,"BLCA,BRCA,CM,HNSC,LUAD,LUSC,OV,STAD",-,-,- PCDH18,-,"BLCA,BRCA,CM,GBM,HNSC,LUSC,PAAD,PRAD,RCCC,UCEC",-,-,- TRIM7,-,-,-,-,High Confidence Driver SVIL,-,-,-,-,Candidate driver CHD9,-,"BLCA,BRCA,CM,COREAD,HNSC,MM,UCEC",-,-,- GPC5,lung adenocarcinoma,-,-,-,- PRDM2,"glioma, colon adenocarcinoma, gastric carcinoma, ovarian carcinoma, HNSCC",-,-,-,Candidate driver MDN1,-,-,-,-,Candidate driver AFF3,"ALL, T-ALL",-,-,-,- FLNA,phyllodes tumour of the breast,-,-,-,Candidate driver CNTRL,"MPN, NHL",-,-,-,- KMT2B,-,-,TSG,2.00%,High Confidence Driver NAV3,-,-,-,4.60%,High Confidence Driver SMARCA1,-,PRAD,-,-,- ROBO2,"colorectal adenocarcinoma, melanoma",UCEC,-,-,- EWSR1,"Ewing sarcoma, desmoplastic small round cell tumour , ALL, clear cell sarcoma, sarcoma, myoepithelioma, mesothelioma",-,-,-,High Confidence Driver MBD1,-,-,-,-,High Confidence Driver TBX3,"breast, large intestine, skin","BLCA,BRCA,CM,COREAD,ESCA,HNSC,LUSC,OV,PRAD,SCLC,STAD,UCEC",-,1.40%,High Confidence Driver PIK3C2B,-,CM,-,-,- DDX6,B-NHL,-,-,-,- EGFR,"glioma, NSCLC","AML,BRCA,CLL,COREAD,ESCA,GBM,HNSC,LGG,LUAD,LUSC,PRAD,RCCC,STAD,UCEC",Oncogene,4.60%,High Confidence Driver CAMTA1,epithelioid haemangioendothelioma,-,-,-,- RB1,"retinoblastoma, sarcoma, breast, small cell lung carcinoma","ALL,BLCA,BRCA,CLL,CM,GBM,LGG,LUAD,LUSC,NSCLC,OV,SCLC",TSG,3.20%,High Confidence Driver NMT2,-,-,-,-,Candidate driver PTPN6,DLBCL,-,-,-,- ZC3H11A,-,"CM,COREAD,ESCA,HNSC,LUSC,SCLC,STAD,THCA,UCEC",-,-,- DICER1,"sex cord-stromal tumour, TGCT, embryonal rhabdomyosarcoma, pleuropulmonary blastoma, pituitary blastoma, Wilms tumour, thyroid cancer, other tumour types","BLCA,CM,HNSC,RCCC,SCLC,THCA,UCEC",-,-,High Confidence Driver PLCB1,-,"CLL,CM",-,-,- ELL,AL,-,-,-,- FLI1,Ewing sarcoma,-,-,-,- NEK1,-,-,-,-,Candidate driver HOXD11,AML,-,-,-,- NUP93,-,UCEC,-,-,High Confidence Driver DOCK4,-,-,-,-,Candidate driver TSHZ2,-,-,-,1.80%,- SMAD4,"colorectal, pancreatic, small intestine","BLCA,BRCA,CM,COREAD,ESCA,LUAD,LUSC,PAAD,PRAD,STAD",TSG,1.40%,High Confidence Driver DDX3X,"CLL, medulloblastoma","BLCA,BRCA,CLL,CM,HNSC,LGG,LUAD,LUSC,MB,MM,RCCC",-,-,Candidate driver TPM4,ALCL,-,-,-,- IL21R,NHL,-,-,-,- JMJD1C,-,-,-,-,Candidate driver BCL9L,"colorectal cancer, endometrial carcinoma, gastric cancer",-,-,-,Candidate driver CDH10,melanoma,-,-,-,- NTN4,-,"CM,COREAD,LUAD,LUSC,RCCC",-,-,- ARHGAP29,-,CM,-,-,- ERC1,"papillary thyroid, Spitzoid tumour",-,-,-,- SEC31A,-,UCEC,-,-,-