Supplementary Table S1. Characteristics of the genetic variants associated with job involves heavy manual or physical work.,,,,,,,,,,,,,
,F,mF,Isq_unweighted,Isq_weighted,SNP,Effect_allele,Other_allele,CHROM,POS,beta,se,eaf,pvalue
1,48.87896995,36.76103728,0.312446173,0,rs1081158,T,C,5,88004616,0.0169887,0.00242996,0.581826,2.70E-12
2,30.78025708,36.76103728,0.312446173,0,rs10820625,C,T,9,99203606,-0.0160068,0.00288515,0.220898,2.90E-08
3,29.90564032,36.76103728,0.312446173,0,rs11130889,G,C,3,62562748,-0.0249218,0.00455725,0.075137,4.50E-08
4,31.03311791,36.76103728,0.312446173,0,rs11663824,A,C,18,50745236,0.0136375,0.00244806,0.396798,2.50E-08
5,30.69205117,36.76103728,0.312446173,0,rs11678979,C,T,2,100802891,-0.0149934,0.00270637,0.271768,3.00E-08
6,44.65318112,36.76103728,0.312446173,0,rs11726786,G,T,4,106120756,0.0165951,0.00248344,0.366352,2.40E-11
7,30.57117149,36.76103728,0.312446173,0,rs11756123,T,A,6,152218079,-0.0137486,0.00248658,0.634651,3.20E-08
8,39.58817087,36.76103728,0.312446173,0,rs12089815,A,G,1,91189933,-0.0151469,0.00240736,0.548546,3.10E-10
9,40.68104492,36.76103728,0.312446173,0,rs1370059,G,A,13,58523077,0.0180816,0.00283492,0.232046,1.80E-10
10,35.95029791,36.76103728,0.312446173,0,rs2091329,G,A,1,110042079,-0.0158895,0.00265008,0.288157,2.00E-09
11,34.76192462,36.76103728,0.312446173,0,rs2318540,G,T,4,67831581,-0.0142827,0.00242247,0.572308,3.70E-09
12,33.9836835,36.76103728,0.312446173,0,rs2819348,C,T,1,201884952,0.0145582,0.00249731,0.352247,5.60E-09
13,32.00584634,36.76103728,0.312446173,0,rs34700731,A,G,2,203360745,0.0197694,0.00349445,0.134891,1.50E-08
14,30.30709566,36.76103728,0.312446173,0,rs3785354,T,C,16,28550667,0.0135824,0.0024672,0.367566,3.70E-08
15,84.96381716,36.76103728,0.312446173,0,rs4580876,A,G,6,98322872,-0.0220715,0.0023945,0.476133,3.00E-20
16,34.64796448,36.76103728,0.312446173,0,rs4731992,G,A,7,133702097,-0.0170407,0.002895,0.781718,4.00E-09
17,34.39386404,36.76103728,0.312446173,0,rs56194430,T,C,5,67824690,0.0188539,0.00321485,0.169355,4.50E-09
18,37.88033747,36.76103728,0.312446173,0,rs62511803,A,G,8,115992376,-0.0211702,0.00343968,0.140624,7.50E-10
19,30.58612928,36.76103728,0.312446173,0,rs6544763,C,T,2,44813233,0.0139692,0.00252586,0.660134,3.20E-08
20,29.76313809,36.76103728,0.312446173,0,rs7108077,G,A,11,95838005,-0.0134395,0.00246345,0.379639,4.90E-08
21,30.23459767,36.76103728,0.312446173,0,rs77823953,T,C,8,143524185,-0.0371641,0.00675883,0.032671,3.80E-08
22,32.48051903,36.76103728,0.312446173,0,rs8054111,G,A,16,71990651,-0.015349,0.0026932,0.729849,1.20E-08