rxns,rxnNames,rxnFormulas,subSystems,CTRL1,CTRL2,CTRL3,IPD1,IPD2,IPD3 ADNt,Adenosine Faciliated Transport in Cytosol,adn[e] <=> adn[c] ,"Transport, extracellular",-1,-1,2,35.59931747,-1,-3418361800 INSt,Transport of Inosine (Diffusion),ins[e] <=> ins[c] ,"Transport, extracellular",1.202777383,-1,-0.202777383,8.726707627,-1,-210333973.2 AKGDm,2-Oxoglutarate Dehydrogenase,akg[m] + nad[m] + coa[m] -> nadh[m] + co2[m] + succoa[m] ,Citric acid cycle,0.024710972,0.523572648,-0.54828362,195556033,-0.192431551,5978903.484 EX_4abut[e],Exchange of 4-Aminobutanoate ,4abut[e] -> ,Exchange/demand reaction,0.294841749,0.284540956,-0.579382704,154334900.5,-0.170200867,3.367894027 EX_cit[e],Exchange of Citrate ,cit[e] -> ,Exchange/demand reaction,-0.031693251,0.753146602,-0.721453351,32867857.72,1.893699403,2.432662484 FUMtr,Transport of Fumarate,fum[e] <=> fum[c] ,"Transport, extracellular",0.937880523,0.062119477,-1,-1,28220055.35,7.236698998 EX_fum[e],Exchange of Fumarate,fum[e] -> ,Exchange/demand reaction,0.936270161,0.063729839,-1,-1,28191540.36,7.228277898 GLNyLATthc,Transport of Glutamine by Y+Lat1 Or Y+Lat2 with Symporter of H,h[e] + gln_L[e] + arg_L[c] -> h[c] + gln_L[c] + arg_L[e] ,"Transport, extracellular",-1,-1,2,14655386.45,12592637.36,-1 NADPtru,"Transport of NADP, Endoplasmic Reticulum",nadp[r] -> nadp[c] ,"Transport, endoplasmic reticular",-1,0.701031776,0.298968224,-1,152.8174356,17471926.09 NADPHtru,"Transport of NADPH, Endoplasmic Reticulum",nadph[c] -> nadph[r] ,"Transport, endoplasmic reticular",-1,0.709761547,0.290238453,-1,151.7722083,17354593.43 EX_creat[e],Exchange of Creatine ,creat[e] -> ,Exchange/demand reaction,1.271106272,-1,-0.271106272,-1,0.329381431,7521724.811 GACMTRc,"Guanidinoacetate N-Methyltransferase, Cytosolic",amet[c] + gudac[c] <=> h[c] + ahcys[c] + creat[c] ,Urea cycle,1.270279869,-1,-0.270279869,-1,0.322589643,6713079.98 r1931,Y+Lat2 Utilized Transport,na1[e] + ser_L[e] + citr_L[c] -> na1[c] + ser_L[c] + citr_L[e] ,"Transport, extracellular",-1,2,-1,-1,-1,5523551.794 C4STMO2Pr,C-4 Methyl Sterol Oxidase,o2[r] + nadp[r] + 4mzym_int2[r] -> h[r] + nadph[r] + co2[r] + zym_int2[r] ,Cholesterol metabolism,0.635632475,-0.298580453,-0.337052022,1.700009381,1225552.444,1225552.443 C3STDH1Pr,C-3 Sterol Dehydrogenase (4-Methylzymosterol),nadp[r] + 4mzym_int1[r] -> h[r] + nadph[r] + co2[r] + 4mzym_int2[r] ,Cholesterol metabolism,0.629966648,-0.290184351,-0.339782297,1.691201651,1220633.582,1220633.582 EX_meoh[e],Exchange of Methanol ,meoh[e] -> ,Exchange/demand reaction,-1,2,-1,5.192495931,1794620.651,-1 MEOHt2,Methanol Diffusion,meoh[e] <=> meoh[c] ,"Transport, extracellular",-1,2,-1,5.189352111,1793818.303,-1 41R1H2MAE12BOOX,"4-[ (1R)-1-Hydroxy-2- (Methylamino)Ethyl]-1, 2-Benzenediol:Oxygen Oxidoreductase (Deaminating) (Flavin-Containing)",h2o[c] + o2[c] + adrnl[c] -> h2o2[c] + 34dhmald[c] + mma[c] ,Tyrosine metabolism,0.603792925,0.396207075,-1,-1,1325925.305,7.264734372 r1991,Y+Lat2 Utilized Transport,na1[e] + citr_L[c] + ile_L[e] -> na1[c] + ile_L[c] + citr_L[e] ,"Transport, extracellular",-1,2,-1,1201792.224,1.166708238,-1 34DHOXPEGOX,"3, 4-Dihydroxyphenylethyleneglycol:NAD+ Oxidoreductase",h[c] + nadh[c] + 34dhmald[c] <=> nad[c] + 34dhoxpeg[c] ,Tyrosine metabolism,0.25041278,0.74958722,-1,3.107617963,1033452.811,5.441624019 34DHOXPEGt,"3, 4-Dihydroxyphenylethyleneglycol Transport (Diffusion)",34dhoxpeg[c] <=> 34dhoxpeg[e] ,"Transport, extracellular",0.251024452,0.748975548,-1,3.107490654,1033447.176,5.441537227 EX_34dhoxpeg[e],"Exchange of 3, 4-Dihydroxyphenylethyleneglycol ",34dhoxpeg[e] -> ,Exchange/demand reaction,0.250203811,0.749796189,-1,3.106730555,1033284.787,5.440557481 MAOX,Methylamine Oxidase,h2o[c] + o2[c] + mma[c] -> h2o2[c] + nh4[c] + fald[c] ,Tyrosine metabolism,0.22122464,0.77877536,-1,3.635490036,1009335.81,5.291199939 EX_no[e],Exchange of Nitric Oxide,no[e] -> ,Exchange/demand reaction,-0.191615981,0.955571614,-0.763955633,-0.400976201,545405.9949,396753.9117 r0145,"L-Arginine, NADPH:Oxygen Oxidoreductase (Nitric-Oxide-Forming)",2 o2[c] + 2 nadph[c] + arg_L[c] -> 2 h2o[c] + 2 nadp[c] + citr_L[c] + no[c] ,Arginine and proline metabolism,-0.191582859,0.955550397,-0.763967538,-0.400953086,545382.4737,396736.8012 NOt,Transport of Nitric Oxide (Diffusion),no[e] <=> no[c] ,"Transport, extracellular",-0.191985628,0.956018888,-0.76403326,-0.401168233,545220.2096,396618.7627 EX_citr_L[e],Exchange of L-Citrulline ,citr_L[e] -> ,Exchange/demand reaction,-0.232979632,1.009324104,-0.776344471,-0.476988491,523115.1973,380538.509 NORANMT,Noradrenaline N-Methyltransferase,amet[c] + nrpphr[c] -> h[c] + ahcys[c] + adrnl[c] ,Tyrosine metabolism,0.26157401,0.551685659,-0.813259669,3.043831586,880409.4708,4.54330005 HMR_6874,"L-Tyrosine, L-Dopa:Oxygen Oxidoreductase",o2[c] + tyr_L[c] -> h2o[c] + dopaqn[c] ,Phenylalanine metabolism,0.570158733,0.02060706,-0.590765793,786407.123,-0.175789102,2.314568733 EBP1r,"3-Beta-Hydroxysteroid-Delta (8), Delta (7)-Isomerase",zymst[r] -> chlstol[r] ,Cholesterol metabolism,0.487495693,0.035905436,-0.523401128,4.82636621,239361.3325,145628.1422 PPAn,"Inorganic Diphosphatase, Nuclear",h2o[n] + ppi[n] -> h[n] + 2 pi[n] ,Miscellaneous,1.235053512,-0.926505219,-0.308548293,-0.562908225,-1,245176.8886 r1380,Delta24-Sterol Reductase,h[r] + nadph[r] + zymst[r] -> nadp[r] + zymstnl[r] ,Cholesterol metabolism,0.526752529,-0.023122516,-0.503630013,4.903474911,8.15810051,206200.6129 HMR_1565,Cholesterol:NADP+ Delta7-Oxidoreductase,h[c] + nadph[c] + 7dhchsterol[c] -> nadp[c] + chsterol[c] ,Cholesterol metabolism,0.728107572,-0.299102747,-0.429004824,1.040198193,158553.5303,-1 DSREDUCr,Desmosterol Reductase,h[r] + nadph[r] + dsmsterol[r] -> nadp[r] + chsterol[r] ,Squalene and cholesterol synthesis,-0.227561986,-0.522353364,0.74991535,2.172447107,-0.248097019,126423.2864 r2393,Mitochondrial Carrier (Mc) Tcdb:2.A.29.7.2,pep[c] + icit[m] -> pep[m] + icit[c] ,"Transport, mitochondrial",-1,2,-1,-1,63270.92187,50069.17963 GTHDH,Glutathione Dehydrogenase (Dehydroascorbate Reductase),dhdascb[c] + 2 gthrd[c] -> h[c] + ascb_L[c] + gthox[c] ,Vitamin C metabolism,-1,2,-1,-1,106179.04,-0.751638076 DOPABMO,Dopamine Beta-Monooxygenase,o2[c] + h[c] + dopa[c] + ascb_L[c] -> h2o[c] + nrpphr[c] + dhdascb[c] ,Tyrosine metabolism,-0.924856096,1.915917904,-0.991061807,-0.745129208,102926.3939,-0.73194702 NRPPHRt4_2_r,"Transport of Norepinephrine via Sodium Symport (1:2), Reversible",2 na1[e] + nrpphr[e] <=> 2 na1[c] + nrpphr[c] ,"Transport, extracellular",-1,2,-1,-0.935209103,64186.11461,-1 EX_nrpphr[e],Exchange of Norepinephrine ,nrpphr[e] -> ,Exchange/demand reaction,-0.984519938,1.984519938,-1,-0.935545621,63853.25095,-0.997091745 5AOPt,"Transport of 5-Amino-4-Oxopentanoate, Proton Symport",2 h[c] + 5aop[c] <=> 2 h[e] + 5aop[e] ,"Transport, extracellular",1.997775965,-0.997911189,-0.999864776,-1,-0.998992116,4541.633568 ALASm,5-Aminolevulinate Synthase,h[m] + gly[m] + succoa[m] -> coa[m] + co2[m] + 5aop[m] ,"Glycine, serine, alanine, and threonine metabolism",1.99777371,-0.997908922,-0.999864788,-1,-0.998991366,4541.631619 GLYtm,"Transport of Glycine, Passive, Mitochondrial",gly[c] <=> gly[m] ,"Transport, mitochondrial",1.997771572,-0.997906839,-0.999864733,-1,-0.998990162,4541.629365 5AOPtm,5-Aminolevulinate Mitochondrial Transport,5aop[c] <=> 5aop[m] ,Heme synthesis,1.997769859,-0.997905062,-0.999864797,-1,-0.998989969,4541.62627 EX_5aop[e],Exchange of 5-Amino-4-Oxopentanoate,5aop[e] -> ,Exchange/demand reaction,1.997769126,-0.997904375,-0.99986475,-1,-0.998991027,4541.623921 ASPt6,"L-Aspartate Transport via Na, H Symport And K Antiport",h[e] + 3 na1[e] + k[c] + asp_L[e] -> h[c] + 3 na1[c] + asp_L[c] + k[e] ,"Transport, extracellular",1.974588226,-0.97470659,-0.999881636,2153.565974,892.0535976,-0.958349353 RE0581C,RE0581C,h[c] + nadph[c] + 3ohodcoa[c] <=> nadp[c] + CE2248[c] ,Fatty acid synthesis,-1,2,-1,-696.6874527,-172.4726217,-739.2535403 PPItr,"Diphosphate Transporter, Endoplasmic Reticulum",ppi[c] <=> ppi[r] ,"Transport, endoplasmic reticular",-113.6688363,217.937646,-104.2688096,218.1482939,217.9550505,82.29617688 H2Otm,"H2O Transport, Mitochondrial",h2o[c] <=> h2o[m] ,"Transport, mitochondrial",-1,-1,2,-1,-1,-464.8393823 r1604,Amino Acid-Polyamine-Organocation (Apc) Tcdb:2.A.3.8.1,met_L[e] + val_L[c] <=> met_L[c] + val_L[e] ,"Transport, extracellular",-24.83220384,25.83220384,-1,-181.7624222,-30.15601212,-134.6372158 HMR_2667,HMR_2667,crn[m] + elaidcrn[c] <=> crn[c] + elaidcrn[m] ,"Transport, mitochondrial",-1,2,-1,-1,-1,-384.2672202