{"text_format":"3","workbook":"xlsx","n_sheets":2,"sheets":["Kegg pathway MCF10a","Reactome pathway MCF10a"],"read":"whole","date_system":"1900"}

{"sheet":"Kegg pathway MCF10a","index":0,"n_rows":32,"n_cols":13,"rows_kept":32}
["Category","Category","Category","Category","Category","Category","Category","Category","Category","Category","Category","Category","Category"]
["KEGG_PATHWAY","hsa00900:Terpenoid backbone biosynthesis",5,5.3763440860215,{"v":1.1493450230048E-5,"d":"1.15E-05"},"ENSG00000067064, ENSG00000120437, ENSG00000112972, ENSG00000167508, ENSG00000160752",55,22,8156,33.7024793388429,1.56189718112054E-3,0.00156310923128653,0.00142518782852596]
["KEGG_PATHWAY","hsa00100:Steroid biosynthesis",4,4.3010752688172,{"v":0.000288833609377581,"d":"2.89E-04"},"ENSG00000052802, ENSG00000104549, ENSG00000147155, ENSG00000172893",55,20,8156,29.6581818181818,0.0385253168315598,0.0167416246428917,0.0152644224685189]
["KEGG_PATHWAY","hsa04657:IL-17 signaling pathway",6,6.4516129032258,{"v":0.000369935186893291,"d":"3.70E-04"},"ENSG00000169245, ENSG00000163734, ENSG00000115009, ENSG00000137745, ENSG00000081041, ENSG00000169429",55,94,8156,9.46537717601547,0.0490753896434035,0.0167416246428917,0.0152644224685189]
["KEGG_PATHWAY","hsa04061:Viral protein interaction with cytokine and cytokine receptor",6,6.4516129032258,{"v":0.000492400724790933,"d":"4.92E-04"},"ENSG00000169245, ENSG00000163734, ENSG00000115009, ENSG00000081041, ENSG00000169429, ENSG00000151882",55,100,8156,8.89745454545454,0.0647888919442537,0.0167416246428917,0.0152644224685189]
["KEGG_PATHWAY","hsa04060:Cytokine-cytokine receptor interaction",9,9.67741935483871,{"v":0.00065043483090838,"d":"6.50E-04"},"ENSG00000164761, ENSG00000169245, ENSG00000163734, ENSG00000115009, ENSG00000081041, ENSG00000169429, ENSG00000151882, ENSG00000122641, ENSG00000092969",55,295,8156,4.52412942989214,0.084685830446628,0.0176918274007079,0.0161307838065278]
["KEGG_PATHWAY","hsa05323:Rheumatoid arthritis",5,5.3763440860215,0.00324201742074335,"ENSG00000163734, ENSG00000115009, ENSG00000081041, ENSG00000169429, ENSG00000092969",55,93,8156,7.97262952101661,0.357012917126195,0.0734857282035161,0.0670016933620294]
["KEGG_PATHWAY","hsa04979:Cholesterol metabolism",4,4.3010752688172,0.00431681276222427,"ENSG00000007944, ENSG00000130164, ENSG00000165029, ENSG00000101670",55,50,8156,11.8632727272727,0.444761409930646,0.0767806004762911,0.070005841610736]
["KEGG_PATHWAY","hsa05146:Amoebiasis",5,5.3763440860215,0.00451650591037006,"ENSG00000163734, ENSG00000115414, ENSG00000081041, ENSG00000169429, ENSG00000092969",55,102,8156,7.26916221033868,0.459702904993468,0.0767806004762911,0.070005841610736]
["KEGG_PATHWAY","hsa01212:Fatty acid metabolism",4,4.3010752688172,0.00623804576564777,"ENSG00000134824, ENSG00000099194, ENSG00000149485, ENSG00000120437",55,57,8156,10.4063795853269,0.573025667504311,0.0942638026808996,0.0859464083267026]
["KEGG_PATHWAY","hsa04062:Chemokine signaling pathway",6,6.4516129032258,0.00853098352164489,"ENSG00000169245, ENSG00000163734, ENSG00000115009, ENSG00000081041, ENSG00000169429, ENSG00000151882",55,192,8156,4.6340909090909,0.688136899646581,0.11602137589437,0.105784195668396]
["KEGG_PATHWAY","hsa03320:PPAR signaling pathway",4,4.3010752688172,0.0132436896962834,"ENSG00000134824, ENSG00000099194, ENSG00000112972, ENSG00000170323",55,75,8156,7.90884848484848,0.836864647830882,0.142122031075413,0.129581851862877]
["KEGG_PATHWAY","hsa05417:Lipid and atherosclerosis",6,6.4516129032258,0.0134765879290911,"ENSG00000160179, ENSG00000163734, ENSG00000130164, ENSG00000081041, ENSG00000169429, ENSG00000165029",55,215,8156,4.1383509513742,0.842018620238066,0.142122031075413,0.129581851862877]
["KEGG_PATHWAY","hsa01040:Biosynthesis of unsaturated fatty acids",3,3.2258064516129,0.0135851941469145,"ENSG00000134824, ENSG00000099194, ENSG00000149485",55,27,8156,16.4767676767676,0.844366461402361,0.142122031075413,0.129581851862877]
["KEGG_PATHWAY","hsa01100:Metabolic pathways",18,19.3548387096774,0.0179536715395682,"ENSG00000052802, ENSG00000134824, ENSG00000067064, ENSG00000149485, ENSG00000112972, ENSG00000104549, ENSG00000139428, ENSG00000172893, ENSG00000099194, ENSG00000085662, ENSG00000120437, ENSG00000163283, ENSG00000187134, ENSG00000167508, ENSG00000147155, ENSG00000100344, ENSG00000101670, ENSG00000160752",55,1539,8156,1.73439659755449,0.914896234393105,0.172285695799429,0.157084016758303]
["KEGG_PATHWAY","hsa04218:Cellular senescence",5,5.3763440860215,0.0194238037447173,"ENSG00000116717, ENSG00000134057, ENSG00000145386, ENSG00000169429, ENSG00000092969",55,156,8156,4.75291375291375,0.93058343586774,0.172285695799429,0.157084016758303]
["KEGG_PATHWAY","hsa04512:ECM-receptor interaction",4,4.3010752688172,0.0202689053881682,"ENSG00000168743, ENSG00000072571, ENSG00000137801, ENSG00000115414",55,88,8156,6.74049586776859,0.938264169685171,0.172285695799429,0.157084016758303]
["KEGG_PATHWAY","hsa04064:NF-kappa B signaling pathway",4,4.3010752688172,0.0312496206153994,"ENSG00000116717, ENSG00000163734, ENSG00000081041, ENSG00000169429",55,104,8156,5.7034965034965,0.986670420758797,0.249996964923195,0.227938409194678]
["KEGG_PATHWAY","hsa04668:TNF signaling pathway",4,4.3010752688172,0.0377034750696907,"ENSG00000169245, ENSG00000163734, ENSG00000115009, ENSG00000081041",55,112,8156,5.29610389610389,0.994629524065892,0.284870700526552,0.259735050480091]
["KEGG_PATHWAY","hsa05144:Malaria",3,3.2258064516129,0.043056039950752,"ENSG00000137801, ENSG00000169429, ENSG00000092969",55,50,8156,8.89745454545454,0.997484844925023,0.308190601752751,0.280997313362802]
["KEGG_PATHWAY","hsa04110:Cell cycle",4,4.3010752688172,0.050508406256049,"ENSG00000116717, ENSG00000134057, ENSG00000145386, ENSG00000092969",55,126,8156,4.7076479076479,0.999131453895262,0.34330878896353,0.313016836996159]
["KEGG_PATHWAY","hsa05134:Legionellosis",3,3.2258064516129,0.0544856401030041,"ENSG00000163734, ENSG00000081041, ENSG00000169429",55,57,8156,7.80478468899521,0.999509244078771,0.34330878896353,0.313016836996159]
["KEGG_PATHWAY","hsa04068:FoxO signaling pathway",4,4.3010752688172,0.0555352452735122,"ENSG00000116717, ENSG00000134057, ENSG00000145632, ENSG00000092969",55,131,8156,4.52796668979875,0.999578048269455,0.34330878896353,0.313016836996159]
["KEGG_PATHWAY","hsa00561:Glycerolipid metabolism",3,3.2258064516129,0.0632313361222971,"ENSG00000085662, ENSG00000100344, ENSG00000101670",55,62,8156,7.17536656891495,0.999861324345263,0.37388963967967,0.340899377354993]
["KEGG_PATHWAY","hsa04936:Alcoholic liver disease",4,4.3010752688172,0.0674025578282819,"ENSG00000099194, ENSG00000163734, ENSG00000081041, ENSG00000169429",55,142,8156,4.17720870678617,0.999924418776526,0.381947827693597,0.348246548779456]
["KEGG_PATHWAY","hsa05120:Epithelial cell signaling in Helicobacter pylori infection",3,3.2258064516129,0.0781251787524972,"ENSG00000163734, ENSG00000081041, ENSG00000169429",55,70,8156,6.35532467532467,0.999984318569812,0.425000972413585,0.387500886612386]
["KEGG_PATHWAY","hsa04115:p53 signaling pathway",3,3.2258064516129,0.0839704488728475,"ENSG00000116717, ENSG00000134057, ENSG00000137801",55,73,8156,6.09414694894147,0.999993397782054,0.429597980545264,0.391692276379506]
["KEGG_PATHWAY","hsa05160:Hepatitis C",4,4.3010752688172,0.085287834372957,"ENSG00000169245, ENSG00000134321, ENSG00000185745, ENSG00000130164",55,157,8156,3.77811233352634,0.999994571424157,0.429597980545264,0.391692276379506]
[]
["infection"]
["inflammation"]
["metabolism/cancer"]

{"sheet":"Reactome pathway MCF10a","index":1,"n_rows":31,"n_cols":14,"rows_kept":31}
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["REACTOME_PATHWAY","R-HSA-191273","Cholesterol biosynthesis",9,9.67741935483871,{"v":6.20646166223236e-12,"d":"6.21E-12"},"ENSG00000052802, ENSG00000067064, ENSG00000120437, ENSG00000112972, ENSG00000167508, ENSG00000104549, ENSG00000147155, ENSG00000172893, ENSG00000160752",75,27,10882,48.3644444444444,{"v":2.1226160829002E-9,"d":"2.12E-09"},{"v":2.12260988848346E-9,"d":"2.12E-09"},{"v":2.0729581951856e-09,"d":"2.07E-09"}]
["REACTOME_PATHWAY","R-HSA-8957322","Metabolism of steroids",13,13.9784946236559,{"v":4.3250311355917E-10,"d":"4.33E-10"},"ENSG00000052802, ENSG00000067064, ENSG00000112972, ENSG00000104549, ENSG00000172893, ENSG00000186480, ENSG00000099194, ENSG00000085662, ENSG00000120437, ENSG00000187134, ENSG00000167508, ENSG00000147155, ENSG00000160752",75,154,10882,12.2481385281385,{"v":1.47916064507924E-7,"d":"1.48E-07"},{"v":7.3958032418618e-08,"d":"7.40E-08"},{"v":7.22280199643814e-08,"d":"7.22E-08"}]
["REACTOME_PATHWAY","R-HSA-1655829","Regulation of cholesterol biosynthesis by SREBP (SREBF)",8,8.60215053763441,{"v":7.8732584867924e-08,"d":"7.87E-08"},"ENSG00000067064, ENSG00000186480, ENSG00000099194, ENSG00000112972, ENSG00000167508, ENSG00000104549, ENSG00000172893, ENSG00000160752",75,55,10882,21.1044848484848,{"v":2.69261825782685e-05,"d":"2.69E-05"},{"v":8.97551467494334e-06,"d":"8.98E-06"},{"v":8.76556111529554e-06,"d":"8.77E-06"}]
["REACTOME_PATHWAY","R-HSA-2426168","Activation of gene expression by SREBF (SREBP)",7,7.5268817204301,{"v":3.47765166723056E-7,"d":"3.48E-07"},"ENSG00000067064, ENSG00000099194, ENSG00000112972, ENSG00000167508, ENSG00000104549, ENSG00000172893, ENSG00000160752",75,42,10882,24.1822222222222,{"v":1.18928635146953E-4,"d":"1.19E-04"},{"v":2.97339217548213e-05,"d":"2.97E-05"},{"v":2.90383914213752E-5,"d":"2.90E-05"}]
["REACTOME_PATHWAY","R-HSA-556833","Metabolism of lipids",19,20.4301075268817,{"v":1.6279756279173E-6,"d":"1.63E-06"},"ENSG00000052802, ENSG00000134824, ENSG00000067064, ENSG00000149485, ENSG00000196542, ENSG00000112972, ENSG00000104549, ENSG00000172893, ENSG00000170323, ENSG00000186480, ENSG00000099194, ENSG00000085662, ENSG00000120437, ENSG00000187134, ENSG00000167508, ENSG00000147155, ENSG00000100344, ENSG00000160752, ENSG00000165029",75,743,10882,3.71032750112157,{"v":5.56613151361684E-4,"d":"5.57E-04"},{"v":0.000111353532949543,"d":"1.11E-04"},{"v":1.08748771944875E-4,"d":"1.09E-04"}]
["REACTOME_PATHWAY","R-HSA-6809371","Formation of the cornified envelope",8,8.60215053763441,{"v":2.73341540796929e-05,"d":"2.73E-05"},"ENSG00000175065, ENSG00000186395, ENSG00000169469, ENSG00000205426, ENSG00000134760, ENSG00000171401, ENSG00000167768, ENSG00000170477",75,130,10882,8.92882051282051,0.00930484793709685,1.5580467825425E-3,0.00152160124376957]
["REACTOME_PATHWAY","R-HSA-380108","Chemokine receptors bind chemokines",6,6.4516129032258,{"v":4.77059476629975e-05,"d":"4.77E-05"},"ENSG00000169245, ENSG00000163734, ENSG00000115009, ENSG00000081041, ENSG00000169429, ENSG00000151882",75,59,10882,14.7552542372881,0.0161834411921455,0.00233077630010645,0.00227625521706302]
["REACTOME_PATHWAY","R-HSA-6805567","Keratinization",8,8.60215053763441,{"v":0.000607512510646265,"d":"6.08E-04"},"ENSG00000175065, ENSG00000186395, ENSG00000169469, ENSG00000205426, ENSG00000134760, ENSG00000171401, ENSG00000167768, ENSG00000170477",75,214,10882,5.42404984423676,0.187656838516231,0.0259711598301278,0.0253636473194815]
["REACTOME_PATHWAY","R-HSA-174824","Plasma lipoprotein assembly, remodeling, and clearance",5,5.3763440860215,0.00158260096510353,"ENSG00000160179, ENSG00000007944, ENSG00000130164, ENSG00000165029, ENSG00000101670",75,74,10882,9.8036036036036,0.418228938344834,0.0601388366739341,0.0587320802605088]
["REACTOME_PATHWAY","R-HSA-9024446","NR1H2 and NR1H3-mediated signaling",4,4.3010752688172,0.00394968025654383,"ENSG00000099194, ENSG00000160179, ENSG00000007944, ENSG00000165029",75,47,10882,12.3483687943262,0.741656526881767,0.119489408633057,0.116694334746903]
["REACTOME_PATHWAY","R-HSA-6783783","Interleukin-10 signaling",4,4.3010752688172,0.00394968025654383,"ENSG00000169245, ENSG00000115009, ENSG00000081041, ENSG00000169429",75,47,10882,12.3483687943262,0.741656526881767,0.119489408633057,0.116694334746903]
["REACTOME_PATHWAY","R-HSA-6791312","TP53 Regulates Transcription of Cell Cycle Genes",4,4.3010752688172,0.00419261082923007,"ENSG00000116717, ENSG00000134057, ENSG00000145386, ENSG00000145632",75,48,10882,12.0911111111111,0.762333575737047,0.119489408633057,0.116694334746903]
["REACTOME_PATHWAY","R-HSA-1430728","Metabolism",24,25.8064516129032,0.0113051794157512,"ENSG00000052802, ENSG00000134824, ENSG00000067064, ENSG00000134827, ENSG00000149485, ENSG00000196542, ENSG00000112972, ENSG00000104549, ENSG00000139428, ENSG00000072571, ENSG00000172893, ENSG00000130164, ENSG00000170323, ENSG00000156689, ENSG00000186480, ENSG00000099194, ENSG00000085662, ENSG00000120437, ENSG00000187134, ENSG00000167508, ENSG00000147155, ENSG00000100344, ENSG00000160752, ENSG00000165029",75,2117,10882,1.64489371752479,0.979521761577874,0.287550644558257,0.280824313691397]
["REACTOME_PATHWAY","R-HSA-375276","Peptide ligand-binding receptors",6,6.4516129032258,0.0117710790170046,"ENSG00000169245, ENSG00000163734, ENSG00000115009, ENSG00000081041, ENSG00000169429, ENSG00000151882",75,201,10882,4.33114427860696,0.982570482155064,0.287550644558257,0.280824313691397]
["REACTOME_PATHWAY","R-HSA-1280215","Cytokine Signaling in Immune system",11,11.8279569892473,0.022296311532849,"ENSG00000164485, ENSG00000164761, ENSG00000126709, ENSG00000169245, ENSG00000134321, ENSG00000115009, ENSG00000197632, ENSG00000115414, ENSG00000185745, ENSG00000081041, ENSG00000169429",75,715,10882,2.23220512820512,0.999552409633132,0.508355902948957,0.496464536798105]
["REACTOME_PATHWAY","R-HSA-6807062","Cholesterol biosynthesis via lathosterol",2,2.1505376344086,0.0269283541495758,"ENSG00000147155, ENSG00000172893",75,4,10882,72.5466666666666,0.999911787988065,0.541735124656173,0.529062957997549]
["REACTOME_PATHWAY","R-HSA-6807047","Cholesterol biosynthesis via desmosterol",2,2.1505376344086,0.0269283541495758,"ENSG00000147155, ENSG00000172893",75,4,10882,72.5466666666666,0.999911787988065,0.541735124656173,0.529062957997549]
["REACTOME_PATHWAY","R-HSA-2046105","Linoleic acid (LA) metabolism",2,2.1505376344086,0.0531411102195664,"ENSG00000134824, ENSG00000149485",75,8,10882,36.2733333333333,0.999999992245402,1,0.979472140762463]
["REACTOME_PATHWAY","R-HSA-418594","G alpha (i) signalling events",6,6.4516129032258,0.0649824706893106,"ENSG00000169245, ENSG00000163734, ENSG00000115009, ENSG00000081041, ENSG00000169429, ENSG00000151882",75,318,10882,2.73761006289308,0.999999999895201,1,0.979472140762463]
["REACTOME_PATHWAY","R-HSA-8964058","HDL remodeling",2,2.1505376344086,0.0659850214417903,"ENSG00000160179, ENSG00000101670",75,10,10882,29.0186666666666,0.999999999927387,1,0.979472140762463]
["REACTOME_PATHWAY","R-HSA-373076","Class A/1 (Rhodopsin-like receptors)",6,6.4516129032258,0.0774212019132234,"ENSG00000169245, ENSG00000163734, ENSG00000115009, ENSG00000081041, ENSG00000169429, ENSG00000151882",75,335,10882,2.59868656716417,0.999999999998925,1,0.979472140762463]
["REACTOME_PATHWAY","R-HSA-2046104","alpha-linolenic (omega3) and linoleic (omega6) acid metabolism",2,2.1505376344086,0.0849292830133084,"ENSG00000134824, ENSG00000149485",75,13,10882,22.3220512820512,0.999999999999934,1,0.979472140762463]
["REACTOME_PATHWAY","R-HSA-2046106","alpha-linolenic acid (ALA) metabolism",2,2.1505376344086,0.0849292830133084,"ENSG00000134824, ENSG00000149485",75,13,10882,22.3220512820512,0.999999999999934,1,0.979472140762463]
["REACTOME_PATHWAY","R-HSA-909733","Interferon alpha/beta signaling",3,3.2258064516129,0.0860288193458518,"ENSG00000126709, ENSG00000134321, ENSG00000185745",75,72,10882,6.04555555555555,0.999999999999956,1,0.979472140762463]
["REACTOME_PATHWAY","R-HSA-449147","Signaling by Interleukins",7,7.5268817204301,0.0936954633565801,"ENSG00000164485, ENSG00000169245, ENSG00000115009, ENSG00000197632, ENSG00000115414, ENSG00000081041, ENSG00000169429",75,462,10882,2.19838383838383,0.999999999999997,1,0.979472140762463]
["REACTOME_PATHWAY","R-HSA-500792","GPCR ligand binding",7,7.5268817204301,0.0974193411449621,"ENSG00000169245, ENSG00000114812, ENSG00000163734, ENSG00000115009, ENSG00000081041, ENSG00000169429, ENSG00000151882",75,467,10882,2.174846538187,0.999999999999999,1,0.979472140762463]
[]
[]
["inflammation"]
["metabolism/cancer"]