KLF11

SNP1, Adjacent sequence (AS)-1659 G>C

5’-gaacagcaagtgcgaggac

5’-gtttaagacgaaagaaccgtgata

SNP2, AS -1552 Ins(ACTTA)

5’-gaacagcaagtgcgaggac

5’-gtttaagacgaaagaaccgtgata

SNP3, AS -1346 A>G

5’-gtcttcatgcgagcagtttatcac

5’-ggaaccatgctgtttattttcgtc

SNP4, AS -1280Ins(CT)

5’-gtcttcatgcgagcagtttatcac

5’-ggaaccatgctgtttattttcgtc

SNP5, AS -1025Ins (G)

5’-gagacgcgagcaaccgaaata

5’-agaggggaccacgcttataggaac

SNP6, AS -990 T>A

5’-gagacgcgagcaaccgaaata

5’-agaggggaccacgcttataggaac

SNP7, Promoter -86 del(GCC)

5’-cgggcacgaattggctggtggtgg

5’-cgctcagacgagtagtcccgc

SNP8, IVS1 +799C>T

5’-gacatcacagggggtttagtg

5’-gaatgagctgatctcttccaaaag

SNP9, E2 +185 A>G, Gln62Arg

5’-ctcggtgtttgttgctatagact

5’-cagggaatcttctcacaagttct

SNP10, IVS2 +987G>C

5’-agaaagcagatttggagagggata

5’-acaggtgtccttgtcgatgg

SNP11, E3 +1185 A>T, Val395Val (rs11687357)

5’-ggcctggtgcagttcaga

5’-gaagatgggccttaaggtgg

SNP12, IVS3 +976 T>C (rs6432052)

5’-ggatagacaatcgcttcag

5’-gggagactatagtaagacctacaa

SNP13, IVS3 +1112 C>T (rs6432053)

5’-ggatagacaatcgcttcag

5’-gggagactatagtaagacctacaa

SNP14, IVS3 +1331 T> C

5’-tttgatcctagtggtttattgtag

5’-gcctgttattgaattggaa

SNP15, IVS3 +1391G>A

5’-tttgatcctagtggtttattgtag

5’-gcctgttattgaattggaa

SNP16, IVS3 +1398 del(A )

5’-tttgatcctagtggtttattgtag

5’-gcctgttattgaattggaa

SNP17, AS +343 G>T (rs4444493)

5’-tttacaaccttttctattga

5’-ttggtgacaggaatgattgc

SNP18, AS +1357 C>T (rs4669522)

5’-ccacctggtcattcattgt

5’-atgtaatcaggaaatggaagtgta

SNP19, AS +1652 T>C

5’-ccacctggtcattcattgt

5’-atgtaatcaggaaatggaagtgta

KLF11 +1039 G>T, Ala347Ser

5’-ggcctggtgcagttcaga

5’-gaagatgggccttaaggtgg

KLF11 +659 C>T, Thr220Met

5’-atctcgtggagccatcg

5’-acagaaatcagaggggtggt

Non-KLF11

1) hCV3216734

5’-ttggttggttttggttctca

5’-ccctccgccccgccttcctc

2) TAF1B-SL1 +16 T>G, Ser6Ala

5’-ttggttggttttggttctca

5’-ccctccgccccgccttcctc

3) hCV1026832

5’-tctcttttatttcagtcttg

5‘-gattctatactctgcttatt

4) hCV3216650

5’-ttactgttttgttcttcaga

5’-tgacgtacacttaccactcg

5) hCV3216649

5’-atggtctagttggcaaataa

5‘-aaaatgttacttgtcataaa

6) LBP32 +1189 C>T, Ile419Val (rs2303920)

5’-tgttgcttatggaaccttct

5’-gctatattctcattttgaca

7) ATCAAG(G/A) chr2, 10 076 994*

5’-tgttgcttatggaaccttct

5’-gctatattctcattttgaca

8) hCV2072927

5’-tcgccagcacaggtctatgt

5‘-cgtagcagatgtcctaaagc

9) AAGGGG(A/G) chr2, 10 110 956

5’-ccctttagagatgctgtgt

5’-cacattctatccgccaaatg

10) hCV2072888

5’-tcgctgttggtattctggt

5’-actgacaggtctctgatgg

11) GCGGGC(G/A) chr2, 10 112 490

5’-acctccctcctccccaacct

5’-tctgcctccagcacttcaac

12) CAGTCT(T/G) chr2, 10 119 738

5‘-agtgagggtctgttgaaatcgt

5‘-agggctttgtctagtatccagg

13) TCATTC(G/C) chr2, 10 119 897

5‘-agtgagggtctgttgaaatcgt

5‘-agggctttgtctagtatccagg

14) ATTCGA(G/A) chr2, 10 119 899

5‘-agtgagggtctgttgaaatcgt

5‘-agggctttgtctagtatccagg

15) ACAATC(G/A) chr2, 10 119 956

5‘-agtgagggtctgttgaaatcgt

5‘-agggctttgtctagtatccagg

16) hCV11792435

5‘-agtgagggtctgttgaaatcgt

5‘-agggctttgtctagtatccagg

17) KLF11 AS+2541 A>G

5’-ctatgatcataccactgcacccta

5’-gaaggaggctccgtaatcaga

18) AAGAGG(C/T) chr2, 10 146 021

5’-ctatgatcataccactgcacccta

5’-gaaggaggctccgtaatcaga

19) rs6736289

5’-ctatgatcataccactgcacccta

5’-gaaggaggctccgtaatcaga

20) CCACCT(C/T) chr2, 10 146 214

5’-ctatgatcataccactgcacccta

5’- gaaggaggctccgtaatcaga

21) AK091299 UTR +2422 A>T, C1

5’-tttaagttcacctacagc

5’-tgccaaatacatctttta

22) rs15380

5’-tttaagttcacctacagc

5’-tgccaaatacatctttta

23) rs6717452

5’-cacacaggagtcccctctagccagcc

5’-cagtgggaggtagagctcgtca

24) rs11688858

5’-cacacaggagtcccctctagccagcc

5’-cagtgggaggtagagctcgtca

25) AK091299 UTR +3107 G>A, C2

5’-cacacaggagtcccctctagccagcc

5’-cagtgggaggtagagctcgtca

26) TGGGCC(C/G) chr2, 10 149 136

5’-tcaggccctgcaagtcaaca

5’-cct ttcaaatccactttcagaccg

27) CTCTGC(G/A) chr2, 10 149 894

5’-ttctgcctcagcctcctgagta

5’-cattgattaaggctgtggtgtgct

28) hCV396866

TaqMan SNP genotyping assays (Applied Biosystems).

29) rs6737737

5’-tctcacagacccaggactgcctac

5’-gagaaatgggcacgggacg

30) ATAGAC(A/G) chr2, 10 153 883

5’-gtattggtgagagaggttac

5’-cctcatcacagaaggaatcaga

31) CTTGGG(C/T) chr2, 10155128

5’-tggtgagtggtagtaacggatatg

5’-gccttgaatgctgagtggaa

32) hCV30988

TaqMan SNP genotyping assays (Applied Biosystems)

33) rs4669526

5’-gtctcgatctcttgacctcatgat

5’-aggcagctctgacttagtcctc

34) rs4233873

5’-gtctcgatctcttgacctcatgat

5’-aggcagctctgacttagtcctc

35) GTTCCC(A/G) chr2, 10 160 531

5’-gtctcgatctcttgacctcatgat

5’-aggcagctctgacttagtcctc

36) rs4233874

5’-gtctcgatctcttgacctcatgat

5’-aggcagctctgacttagtcctc

37) hCV11796645

TaqMan SNP genotyping assays (Applied Biosystems)

38) CGTCCC(C/T) chr2, 10 170 603

5’-gcacgcaagtcggaggct

5’-cgacggcagggacgaga

39) GG CTCC(G/A) chr2, 10 170 688

5’-gcacgcaagtcggaggct

5’-cgacggcagggacgaga

40) ATCTAC(T/G) chr2, 10 174 491

5’-gaggactacagttggtgatacttt

5’-ttatgtttcaaatgccgtct

41) CCATTA(A/G) chr2, 10 176 157

5’-cctggcccactgagtaagacga

5’-accaggcagcttccacattagaga

42) rs1130609

5’-aaggctgctggagtgaggggtc

5’-cgtgtgagtgaggagcggcttc

43) rs7587317

5’-gcatggagtcttggggagccta

5’-aggagtggaagatgccgacc

44) rs6715077

5’- ctcagacataaatgcacttgga

5’- tggaaaaacatacaagacgagg

45) rs4302193

5’-tcctaagaccctgtttcctgtact

5’-ctatctggctttcactaacaccct

46) rs6741290

5’- gttgtatctcttattgcgaatg

5’- tgtaatctgaacttcttggcta

47) RRM2 IVS8 -177 A/G, rs4668664

5’- tattactgagctttgcctttcc

5’- gccatactgagagcacttgaac