Tang et al. 10.1073/pnas.0501159102.

Supporting Information

Files in this Data Supplement:

Supporting Figure 8
Supporting Figure 9
Supporting Figure 10




Supporting Figure 8

Fig 8. Sequence of STAT6(B).





Supporting Figure 9

Fig. 9. Identification of a previously unknown gene, STAT6(B). Comparison of the amino acid sequence of STAT6(A) with STAT6(B). Missing amino acid sequences are shown with a dashed line. The transcriptional start site is indicated by a +1, appearing above the sequence for STAT6(A), but beneath that of STAT6(B). The region showing homologous amino acids is denoted with short vertical lines [from STAT6(B) +151 to +404]. The different amino acid regions are STAT6(B) at +1 to +150, and also amino acid S at +292 and amino acid T at +324. An SH2 domain [from STAT6(A) at +532 to +622] is underlined in the sequence of STAT6(A) (1, 2).

1. Dimri, G. P., Lee, X., Basile, G. & Campisi, J. (1995) Proc. Natl. Acad. Sci. USA 92, 9363-9367.

2. Mikita, T., Daniel, C., Wu, P. & Schindler, U. (1998) J. Biol. Chem. 273, 17634-17642.





Supporting Figure 10

Fig. 10. Cytokine antibody array of DNA-transfected THP-1 cells. (a) Map of the human cytokine membrane. (b) The membranes were blotted with equal amounts of conditioned medium from empty vector (b1), LITAF (b2), STAT6(B) (b3), or both LITAF and STAT6(B) (b4) transiently transfected cells.