analysis,subset,ID,setSize,enrichmentScore,NES,pvalue,p.adjust,qvalue, pairedCase_vs_pairedCtrl,NA,REACTOME_EUKARYOTIC_TRANSLATION_INITIATION,94,-0.65,-2.28,1.00E-10,7.59E-08,7.21E-08, pairedCase_vs_pairedCtrl,NA,REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION,77,-0.66,-2.23,8.11E-10,3.08E-07,2.92E-07, pairedCase_vs_pairedCtrl,NA,GOBP_CYTOPLASMIC_TRANSLATION,109,-0.62,-2.19,1.00E-10,1.94E-07,1.82E-07, pairedCase_vs_pairedCtrl,NA,KEGG_RIBOSOME,72,-0.65,-2.19,8.66E-09,1.46E-06,1.39E-06, pairedCase_vs_pairedCtrl,NA,REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY,77,-0.64,-2.18,4.33E-09,9.38E-07,8.92E-07, pairedCase_vs_pairedCtrl,NA,REACTOME_CELLULAR_RESPONSE_TO_STARVATION,100,-0.61,-2.12,4.22E-09,9.38E-07,8.92E-07, pairedCase_vs_pairedCtrl,NA,GOBP_REGULATION_OF_PLATELET_ACTIVATION,25,0.6,2.12,0.000471293,0.035153636,0.032965081, pairedCase_vs_pairedCtrl,NA,REACTOME_RRNA_PROCESSING,102,-0.6,-2.11,3.87E-09,9.38E-07,8.92E-07, pairedCase_vs_pairedCtrl,NA,REACTOME_TRANSLATION,147,-0.58,-2.08,1.00E-10,7.59E-08,7.21E-08, pairedCase_vs_pairedCtrl,NA,REACTOME_INFLUENZA_INFECTION,103,-0.59,-2.08,1.06E-08,1.60E-06,1.52E-06, pairedCase_vs_pairedCtrl,NA,GOBP_RIBONUCLEOPROTEIN_COMPLEX_BIOGENESIS,145,-0.58,-2.05,1.00E-10,1.94E-07,1.82E-07, pairedCase_vs_pairedCtrl,NA,REACTOME_NONSENSE_MEDIATED_DECAY_NMD,92,-0.59,-2.05,3.04E-07,4.19E-05,3.98E-05, pairedCase_vs_pairedCtrl,NA,GOBP_RIBOSOME_BIOGENESIS,90,-0.59,-2.04,7.83E-08,3.52E-05,3.30E-05, pairedCase_vs_pairedCtrl,NA,REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE,89,-0.58,-2.03,5.53E-07,6.99E-05,6.64E-05, pairedCase_vs_pairedCtrl,NA,GOBP_RRNA_METABOLIC_PROCESS,78,-0.6,-2.03,4.12E-07,0.000159619,0.000149682, pairedCase_vs_pairedCtrl,NA,REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S,48,-0.64,-2.02,8.70E-06,0.000943037,0.000896479, pairedCase_vs_pairedCtrl,NA,GOBP_NATURAL_KILLER_CELL_ACTIVATION,28,-0.69,-1.98,6.13E-05,0.007796774,0.007311371, pairedCase_vs_pairedCtrl,NA,GOBP_NCRNA_METABOLIC_PROCESS,131,-0.55,-1.97,3.45E-08,1.83E-05,1.71E-05, pairedCase_vs_pairedCtrl,NA,GOBP_NCRNA_PROCESSING,104,-0.56,-1.96,9.88E-07,0.0003024,0.000283573, pairedCase_vs_pairedCtrl,NA,GOBP_RIBONUCLEOPROTEIN_COMPLEX_SUBUNIT_ORGANIZATION,83,-0.56,-1.92,1.48E-05,0.002719006,0.00254973, pairedCase_vs_pairedCtrl,NA,REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL,28,-0.68,-1.92,0.000112621,0.008991896,0.008547963, pairedCase_vs_pairedCtrl,NA,REACTOME_HDMS_DEMETHYLATE_HISTONES,11,-0.81,-1.91,0.000219367,0.013865834,0.013181274, pairedCase_vs_pairedCtrl,NA,REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS,126,-0.53,-1.89,7.60E-07,8.87E-05,8.44E-05, pairedCase_vs_pairedCtrl,NA,HALLMARK_INTERFERON_GAMMA_RESPONSE,78,-0.56,-1.89,2.41E-05,0.001131032,0.001038573, pairedCase_vs_pairedCtrl,NA,REACTOME_SELENOAMINO_ACID_METABOLISM,80,-0.55,-1.89,1.12E-05,0.001132526,0.001076612, pairedCase_vs_pairedCtrl,NA,GOBP_LYMPHOCYTE_MEDIATED_IMMUNITY,89,-0.55,-1.89,1.06E-05,0.002474659,0.002320595, pairedCase_vs_pairedCtrl,NA,GOBP_HOMOTYPIC_CELL_CELL_ADHESION,56,0.45,1.89,0.000789745,0.048365627,0.045354534, pairedCase_vs_pairedCtrl,NA,REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES,33,-0.64,-1.88,0.000158985,0.010962769,0.010421534, pairedCase_vs_pairedCtrl,NA,REACTOME_INTERFERON_ALPHA_BETA_SIGNALING,25,-0.68,-1.88,0.000195703,0.01290787,0.012270605, pairedCase_vs_pairedCtrl,NA,GOBP_RIBOSOME_ASSEMBLY,27,-0.66,-1.88,0.000309007,0.026055085,0.024432977, pairedCase_vs_pairedCtrl,NA,GOBP_HISTONE_LYSINE_DEMETHYLATION,13,-0.77,-1.88,0.00033976,0.027841193,0.026107888, pairedCase_vs_pairedCtrl,NA,HALLMARK_ALLOGRAFT_REJECTION,69,-0.56,-1.86,8.59E-05,0.002018716,0.001853692, pairedCase_vs_pairedCtrl,NA,GOBP_NUCLEIC_ACID_PHOSPHODIESTER_BOND_HYDROLYSIS,64,-0.56,-1.86,7.31E-05,0.008509162,0.007979408, pairedCase_vs_pairedCtrl,NA,GOBP_LYMPHOCYTE_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE,62,-0.57,-1.86,9.14E-05,0.010029015,0.00940464, pairedCase_vs_pairedCtrl,NA,REACTOME_TRAF6_MEDIATED_NF_KB_ACTIVATION,12,-0.78,-1.86,0.000821919,0.040826311,0.038810704, pairedCase_vs_pairedCtrl,NA,GOBP_PROTEIN_DEMETHYLATION,14,-0.75,-1.86,0.000659773,0.044458498,0.041690651, pairedCase_vs_pairedCtrl,NA,GOBP_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE,101,-0.53,-1.84,1.81E-05,0.00319075,0.002992104, pairedCase_vs_pairedCtrl,NA,REACTOME_INTERFERON_SIGNALING,72,-0.55,-1.84,0.000133886,0.009671648,0.009194156, pairedCase_vs_pairedCtrl,NA,REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2,67,0.42,1.84,0.00027687,0.01680045,0.015971007, pairedCase_vs_pairedCtrl,NA,GOBP_T_CELL_MEDIATED_IMMUNITY,33,-0.62,-1.83,0.000786332,0.048365627,0.045354534, pairedCase_vs_pairedCtrl,NA,REACTOME_METABOLISM_OF_RNA,327,-0.48,-1.82,3.07E-10,1.55E-07,1.47E-07, pairedCase_vs_pairedCtrl,NA,REACTOME_DDX58_IFIH1_MEDIATED_INDUCTION_OF_INTERFERON_ALPHA_BETA,39,-0.6,-1.82,0.000768822,0.040217323,0.038231782, pairedCase_vs_pairedCtrl,NA,GOBP_PEPTIDE_BIOSYNTHETIC_PROCESS,285,-0.48,-1.8,2.21E-09,1.43E-06,1.34E-06, pairedCase_vs_pairedCtrl,NA,GOBP_B_CELL_ACTIVATION,89,-0.52,-1.8,0.000128583,0.013601774,0.01275497, pairedCase_vs_pairedCtrl,NA,GOBP_AMIDE_BIOSYNTHETIC_PROCESS,331,-0.47,-1.78,1.33E-09,9.69E-07,9.09E-07, pairedCase_vs_pairedCtrl,NA,REACTOME_SUMOYLATION,81,-0.52,-1.78,0.000345956,0.019965425,0.018979726, pairedCase_vs_pairedCtrl,NA,GOBP_REGULATION_OF_B_CELL_ACTIVATION,48,-0.57,-1.78,0.000502257,0.036526635,0.0342526, pairedCase_vs_pairedCtrl,NA,GOBP_RNA_PROCESSING,349,-0.47,-1.77,8.37E-10,8.11E-07,7.61E-07, pairedCase_vs_pairedCtrl,NA,GOBP_LEUKOCYTE_MEDIATED_IMMUNITY,132,-0.5,-1.77,1.29E-05,0.002620533,0.002457387, pairedCase_vs_pairedCtrl,NA,GOBP_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY,85,-0.51,-1.77,0.00017487,0.017244003,0.016170445, pairedCase_vs_pairedCtrl,NA,GOBP_ADAPTIVE_IMMUNE_RESPONSE_BASED_ON_SOMATIC_RECOMBINATION_OF_IMMUNE_RECEPTORS_BUILT_FROM_IMMUNOGLOBULIN_SUPERFAMILY_DOMAINS,82,-0.52,-1.77,0.00024271,0.021617,0.020271193, pairedCase_vs_pairedCtrl,NA,GOBP_LEUKOCYTE_MEDIATED_CYTOTOXICITY,47,-0.56,-1.77,0.000727536,0.04745302,0.044498743, pairedCase_vs_pairedCtrl,NA,GOBP_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY,53,-0.55,-1.75,0.000344828,0.027864025,0.026129297, pairedCase_vs_pairedCtrl,NA,REACTOME_SIGNALING_BY_ROBO_RECEPTORS,147,-0.48,-1.74,2.40E-05,0.002273677,0.002161425, pairedCase_vs_pairedCtrl,NA,GOBP_IMMUNE_EFFECTOR_PROCESS,189,-0.47,-1.7,1.18E-05,0.002551525,0.002392675, pairedCase_vs_pairedCtrl,NA,GOBP_RESPONSE_TO_VIRUS,141,-0.47,-1.69,6.85E-05,0.008177317,0.007668223, pairedCase_vs_pairedCtrl,NA,GOBP_DEFENSE_RESPONSE_TO_SYMBIONT,96,-0.49,-1.69,0.000806586,0.048882464,0.045839194, pairedCase_vs_pairedCtrl,NA,GOBP_ADAPTIVE_IMMUNE_RESPONSE,115,-0.48,-1.68,0.000316023,0.026265989,0.024630751, pairedCase_vs_pairedCtrl,NA,GOBP_PEPTIDE_METABOLIC_PROCESS,347,-0.43,-1.64,7.38E-07,0.000252556,0.000236833, pairedCase_vs_pairedCtrl,NA,HALLMARK_E2F_TARGETS,72,-0.49,-1.64,0.002022686,0.026876529,0.024679455, pairedCase_vs_pairedCtrl,NA,GOBP_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS,118,-0.46,-1.63,0.000493593,0.03635091,0.034087816, pairedCase_vs_pairedCtrl,NA,GOBP_IMMUNE_RESPONSE_REGULATING_SIGNALING_PATHWAY,155,-0.45,-1.62,0.000222667,0.021237287,0.01991512, pairedCase_vs_pairedCtrl,NA,GOBP_REGULATION_OF_IMMUNE_RESPONSE,279,-0.43,-1.61,8.47E-06,0.002054143,0.001926258, pairedCase_vs_pairedCtrl,NA,GOBP_LYMPHOCYTE_ACTIVATION,238,-0.44,-1.61,4.21E-05,0.005973203,0.00560133, pairedCase_vs_pairedCtrl,NA,GOBP_IMMUNE_RESPONSE,471,-0.42,-1.6,1.34E-07,5.56E-05,5.22E-05, pairedCase_vs_pairedCtrl,NA,GOBP_DEFENSE_RESPONSE_TO_OTHER_ORGANISM,314,-0.43,-1.6,1.14E-05,0.002544032,0.002385649, pairedCase_vs_pairedCtrl,NA,HALLMARK_MYC_TARGETS_V1,118,-0.45,-1.59,0.002287364,0.026876529,0.024679455, pairedCase_vs_pairedCtrl,NA,GOBP_INNATE_IMMUNE_RESPONSE,244,-0.42,-1.57,6.16E-05,0.007796774,0.007311371, pairedCase_vs_pairedCtrl,NA,GOBP_POSITIVE_REGULATION_OF_IMMUNE_RESPONSE,170,-0.43,-1.56,0.000436585,0.034094849,0.03197221, pairedCase_vs_pairedCtrl,NA,GOBP_DNA_REPAIR,173,-0.43,-1.56,0.000439518,0.034094849,0.03197221, pairedCase_vs_pairedCtrl,NA,REACTOME_NEUTROPHIL_DEGRANULATION,232,-0.41,-1.53,0.00035535,0.019965425,0.018979726, pairedCase_vs_pairedCtrl,NA,GOBP_CELLULAR_AMIDE_METABOLIC_PROCESS,433,-0.4,-1.52,1.50E-05,0.002719006,0.00254973, pairedCase_vs_pairedCtrl,NA,GOBP_BIOLOGICAL_PROCESS_INVOLVED_IN_INTERSPECIES_INTERACTION_BETWEEN_ORGANISMS,484,-0.39,-1.47,2.31E-05,0.003946188,0.003700511, pairedCase_vs_pairedCtrl,NA,GOBP_DNA_METABOLIC_PROCESS,286,-0.39,-1.45,0.000833875,0.050015281,0.046901486, pairedCase_vs_pairedCtrl,NA,GOBP_DEFENSE_RESPONSE,445,-0.38,-1.43,0.00020787,0.020156476,0.018901597, pairedCase_vs_pairedCtrl,NA,REACTOME_INNATE_IMMUNE_SYSTEM,452,-0.37,-1.41,0.000847194,0.040826311,0.038810704, case_vs_ctrl,Baseline,REACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM,14,-0.79,-2.36,8.91E-06,0.000469382,0.000411417, case_vs_ctrl,Baseline,GOBP_POSITIVE_REGULATION_OF_LIPID_CATABOLIC_PROCESS,11,-0.81,-2.32,7.33E-05,0.003896839,0.003507074, case_vs_ctrl,Baseline,REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION,79,0.67,2.27,1.00E-10,1.79E-08,1.57E-08, case_vs_ctrl,Baseline,KEGG_RIBOSOME,76,0.68,2.26,1.00E-10,1.79E-08,1.57E-08, case_vs_ctrl,Baseline,REACTOME_EUKARYOTIC_TRANSLATION_INITIATION,103,0.65,2.25,1.00E-10,1.79E-08,1.57E-08, case_vs_ctrl,Baseline,REACTOME_RRNA_PROCESSING,139,0.64,2.24,1.00E-10,1.79E-08,1.57E-08, case_vs_ctrl,Baseline,REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY,84,0.66,2.22,1.00E-10,1.79E-08,1.57E-08, case_vs_ctrl,Baseline,GOBP_POSITIVE_REGULATION_OF_SMOOTH_MUSCLE_CONTRACTION,11,-0.77,-2.22,0.000328022,0.011053191,0.009947641, case_vs_ctrl,Baseline,REACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS,22,-0.63,-2.19,0.000141116,0.003776432,0.003310073, case_vs_ctrl,Baseline,GOBP_CGMP_MEDIATED_SIGNALING,10,-0.79,-2.19,0.000233824,0.008600989,0.007740711, case_vs_ctrl,Baseline,GOBP_HEPARAN_SULFATE_PROTEOGLYCAN_METABOLIC_PROCESS,10,-0.79,-2.19,0.000237626,0.008657411,0.00779149, case_vs_ctrl,Baseline,GOBP_PROTEOGLYCAN_METABOLIC_PROCESS,21,-0.63,-2.18,0.000317587,0.01089663,0.009806739, case_vs_ctrl,Baseline,REACTOME_INFLUENZA_INFECTION,131,0.62,2.18,1.00E-10,1.79E-08,1.57E-08, case_vs_ctrl,Baseline,GOBP_CALCIUM_ION_REGULATED_EXOCYTOSIS,24,-0.60,-2.17,0.00023486,0.008600989,0.007740711, case_vs_ctrl,Baseline,GOBP_MEMBRANE_REPOLARIZATION,13,-0.71,-2.14,0.000749532,0.020082773,0.018074077, case_vs_ctrl,Baseline,GOBP_CYTOPLASMIC_TRANSLATION,119,0.62,2.13,1.00E-10,3.72E-08,3.35E-08, case_vs_ctrl,Baseline,REACTOME_SELENOAMINO_ACID_METABOLISM,84,0.63,2.13,2.83E-09,3.38E-07,2.97E-07, case_vs_ctrl,Baseline,GOBP_RIBOSOME_BIOGENESIS,158,0.60,2.12,1.00E-10,3.72E-08,3.35E-08, case_vs_ctrl,Baseline,REACTOME_NONSENSE_MEDIATED_DECAY_NMD,101,0.62,2.12,1.15E-10,1.87E-08,1.64E-08, case_vs_ctrl,Baseline,GOBP_PROTEOGLYCAN_BIOSYNTHETIC_PROCESS,19,-0.62,-2.12,0.000707976,0.019470724,0.017523246, case_vs_ctrl,Baseline,GOBP_RIBONUCLEOPROTEIN_COMPLEX_BIOGENESIS,248,0.58,2.10,1.00E-10,3.72E-08,3.35E-08, case_vs_ctrl,Baseline,GOBP_B_CELL_ACTIVATION,146,0.60,2.10,1.00E-10,3.72E-08,3.35E-08, case_vs_ctrl,Baseline,REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE,96,0.61,2.10,8.31E-10,1.15E-07,1.00E-07, case_vs_ctrl,Baseline,REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S,54,0.65,2.09,1.00E-07,9.99E-06,8.76E-06, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_PLATELET_ACTIVATION,32,-0.53,-2.09,0.000383927,0.012505063,0.011254296, case_vs_ctrl,Baseline,GOBP_RRNA_METABOLIC_PROCESS,139,0.59,2.08,1.00E-10,3.72E-08,3.35E-08, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_DIFFERENTIATION,24,0.73,2.08,6.29E-06,0.000488898,0.000439998, case_vs_ctrl,Baseline,REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES,22,0.77,2.07,1.60E-06,0.000130053,0.000113993, case_vs_ctrl,Baseline,REACTOME_CELLULAR_RESPONSE_TO_STARVATION,118,0.59,2.07,7.67E-10,1.15E-07,1.00E-07, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_CALCIUM_ION_DEPENDENT_EXOCYTOSIS,14,-0.67,-2.07,0.001238608,0.03000399,0.027002966, case_vs_ctrl,Baseline,GOBP_POSITIVE_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_DIFFERENTIATION,15,0.81,2.07,6.04E-06,0.000481417,0.000433266, case_vs_ctrl,Baseline,REACTOME_TRNA_PROCESSING_IN_THE_NUCLEUS,35,0.69,2.06,2.23E-06,0.000173519,0.00015209, case_vs_ctrl,Baseline,GOBP_MONOAMINE_TRANSPORT,25,-0.56,-2.05,0.000854196,0.021920864,0.01972832, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_COAGULATION,31,-0.53,-2.05,0.000914301,0.023079564,0.020771126, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_NEURON_PROJECTION_REGENERATION,13,-0.68,-2.05,0.001674786,0.037940344,0.034145518, case_vs_ctrl,Baseline,REACTOME_NUCLEAR_IMPORT_OF_REV_PROTEIN,24,0.74,2.05,4.10E-06,0.000262655,0.000230219, case_vs_ctrl,Baseline,GOBP_RIBOSOMAL_LARGE_SUBUNIT_BIOGENESIS,36,0.68,2.04,6.13E-06,0.000481417,0.000433266, case_vs_ctrl,Baseline,REACTOME_ECM_PROTEOGLYCANS,20,-0.61,-2.04,0.000676602,0.014977118,0.013127565, case_vs_ctrl,Baseline,HALLMARK_ALLOGRAFT_REJECTION,101,0.60,2.04,2.30E-09,1.15E-07,8.22E-08, case_vs_ctrl,Baseline,GOBP_NCRNA_PROCESSING,183,0.57,2.04,1.00E-10,3.72E-08,3.35E-08, case_vs_ctrl,Baseline,KEGG_PRIMARY_IMMUNODEFICIENCY,16,0.81,2.04,9.16E-06,0.000469382,0.000411417, case_vs_ctrl,Baseline,REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS,141,0.58,2.03,1.00E-10,1.79E-08,1.57E-08, case_vs_ctrl,Baseline,REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2,89,-0.42,-2.02,4.34E-06,0.000268421,0.000235273, case_vs_ctrl,Baseline,REACTOME_TRANSLATION,189,0.56,2.02,1.00E-10,1.79E-08,1.57E-08, case_vs_ctrl,Baseline,GOBP_B_CELL_PROLIFERATION,43,0.66,2.01,1.12E-06,0.000114613,0.000103149, case_vs_ctrl,Baseline,REACTOME_RRNA_MODIFICATION_IN_THE_NUCLEUS_AND_CYTOSOL,40,0.66,2.01,2.77E-06,0.00019895,0.000174381, case_vs_ctrl,Baseline,REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN,20,0.75,2.01,1.40E-05,0.000598248,0.000524369, case_vs_ctrl,Baseline,REACTOME_METABOLISM_OF_RNA,477,0.54,2.00,1.00E-10,1.79E-08,1.57E-08, case_vs_ctrl,Baseline,GOBP_CARDIAC_MUSCLE_CELL_MEMBRANE_REPOLARIZATION,10,-0.72,-1.99,0.002330594,0.048735625,0.043861047, case_vs_ctrl,Baseline,REACTOME_INTERACTIONS_OF_REV_WITH_HOST_CELLULAR_PROTEINS,26,0.71,1.99,1.76E-05,0.00067098,0.000588119, case_vs_ctrl,Baseline,REACTOME_SNRNP_ASSEMBLY,32,0.68,1.99,1.19E-05,0.000561251,0.000491941, case_vs_ctrl,Baseline,REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS,26,0.71,1.99,1.80E-05,0.00067098,0.000588119, case_vs_ctrl,Baseline,REACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS,34,0.68,1.99,6.46E-06,0.000373708,0.000327559, case_vs_ctrl,Baseline,REACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA,26,0.71,1.98,1.86E-05,0.000682325,0.000598063, case_vs_ctrl,Baseline,GOBP_LYMPHOCYTE_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE,99,0.58,1.98,1.99E-08,3.50E-06,3.15E-06, case_vs_ctrl,Baseline,REACTOME_EXPORT_OF_VIRAL_RIBONUCLEOPROTEINS_FROM_NUCLEUS,22,0.73,1.97,1.47E-05,0.000613735,0.000537944, case_vs_ctrl,Baseline,GOBP_RIBOSOME_ASSEMBLY,35,0.66,1.97,2.78E-05,0.001816163,0.001634509, case_vs_ctrl,Baseline,GOBP_T_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE,47,0.64,1.97,1.46E-06,0.000141132,0.000127016, case_vs_ctrl,Baseline,GOBP_POSITIVE_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION,18,0.75,1.96,3.21E-05,0.002010343,0.001809267, case_vs_ctrl,Baseline,GOBP_NEGATIVE_REGULATION_OF_DNA_REPLICATION,12,0.81,1.96,7.44E-05,0.003925162,0.003532564, case_vs_ctrl,Baseline,REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS,33,0.67,1.96,1.22E-05,0.000562156,0.000492735, case_vs_ctrl,Baseline,REACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS,28,0.69,1.96,2.20E-05,0.000772071,0.000676727, case_vs_ctrl,Baseline,REACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS,43,0.63,1.96,1.32E-05,0.000578083,0.000506695, case_vs_ctrl,Baseline,HALLMARK_INTERFERON_GAMMA_RESPONSE,132,0.56,1.95,6.91E-09,1.73E-07,1.24E-07, case_vs_ctrl,Baseline,GOBP_B_CELL_DIFFERENTIATION,67,0.59,1.95,2.72E-06,0.000249316,0.000224379, case_vs_ctrl,Baseline,REACTOME_TRNA_PROCESSING,50,0.62,1.95,7.82E-06,0.000437965,0.00038388, case_vs_ctrl,Baseline,REACTOME_TCR_SIGNALING,98,0.57,1.95,2.75E-07,2.60E-05,2.28E-05, case_vs_ctrl,Baseline,REACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS,33,0.67,1.95,1.69E-05,0.000663481,0.000581546, case_vs_ctrl,Baseline,GOBP_NCRNA_METABOLIC_PROCESS,236,0.54,1.94,1.00E-10,3.72E-08,3.35E-08, case_vs_ctrl,Baseline,REACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS,69,0.59,1.94,2.47E-06,0.000184528,0.00016174, case_vs_ctrl,Baseline,GOBP_RESPONSE_TO_PROTOZOAN,12,0.80,1.94,0.000135472,0.005784594,0.005206014, case_vs_ctrl,Baseline,REACTOME_SYNDECAN_INTERACTIONS,13,-0.66,-1.94,0.00291076,0.041420572,0.036305465, case_vs_ctrl,Baseline,REACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE,54,0.61,1.94,8.16E-06,0.000443268,0.000388528, case_vs_ctrl,Baseline,GOBP_RIBONUCLEOPROTEIN_COMPLEX_SUBUNIT_ORGANIZATION,126,0.56,1.93,2.08E-08,3.50E-06,3.15E-06, case_vs_ctrl,Baseline,REACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS,36,0.65,1.93,4.51E-05,0.001470817,0.001289183, case_vs_ctrl,Baseline,GOBP_PLATELET_AGGREGATION,54,-0.44,-1.93,0.000591699,0.017425524,0.015682608, case_vs_ctrl,Baseline,REACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS,53,0.61,1.92,1.00E-05,0.000498141,0.000436625, case_vs_ctrl,Baseline,REACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY,23,0.70,1.92,6.25E-05,0.00193338,0.001694623, case_vs_ctrl,Baseline,KEGG_LEISHMANIA_INFECTION,42,0.62,1.92,4.91E-05,0.001572695,0.00137848, case_vs_ctrl,Baseline,GOBP_RIBOSOMAL_SMALL_SUBUNIT_BIOGENESIS,42,0.63,1.92,3.43E-05,0.002128924,0.001915987, case_vs_ctrl,Baseline,REACTOME_SIGNALING_BY_ROBO_RECEPTORS,165,0.54,1.91,1.14E-09,1.46E-07,1.28E-07, case_vs_ctrl,Baseline,GOBP_CELL_CELL_ADHESION_MEDIATED_BY_INTEGRIN,11,0.81,1.91,0.000226006,0.008407414,0.007566498, case_vs_ctrl,Baseline,GOBP_B_CELL_RECEPTOR_SIGNALING_PATHWAY,41,0.62,1.90,7.54E-05,0.003948189,0.003553288, case_vs_ctrl,Baseline,GOBP_IMMUNE_RESPONSE_REGULATING_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY,152,0.54,1.90,1.60E-08,3.06E-06,2.76E-06, case_vs_ctrl,Baseline,GOBP_POSITIVE_REGULATION_OF_PHAGOCYTOSIS,31,0.64,1.89,0.000135858,0.005784594,0.005206014, case_vs_ctrl,Baseline,GOBP_ANTIGEN_RECEPTOR_MEDIATED_SIGNALING_PATHWAY,115,0.55,1.89,9.78E-08,1.21E-05,1.09E-05, case_vs_ctrl,Baseline,GOBP_MATURATION_OF_LSU_RRNA,16,0.73,1.88,0.000280319,0.009857179,0.008871256, case_vs_ctrl,Baseline,REACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS,25,0.68,1.88,5.75E-05,0.001808423,0.001585098, case_vs_ctrl,Baseline,GOBP_LYMPHOCYTE_MEDIATED_IMMUNITY,129,0.54,1.88,6.57E-08,8.60E-06,7.74E-06, case_vs_ctrl,Baseline,GOBP_ADAPTIVE_IMMUNE_RESPONSE_BASED_ON_SOMATIC_RECOMBINATION_OF_IMMUNE_RECEPTORS_BUILT_FROM_IMMUNOGLOBULIN_SUPERFAMILY_DOMAINS,135,0.54,1.88,4.64E-08,6.56E-06,5.91E-06, case_vs_ctrl,Baseline,GOBP_NEGATIVE_REGULATION_OF_B_CELL_ACTIVATION,21,0.68,1.88,0.000525662,0.015743127,0.014168486, case_vs_ctrl,Baseline,REACTOME_NS1_MEDIATED_EFFECTS_ON_HOST_PATHWAYS,30,0.65,1.88,0.000108027,0.00306088,0.002682886, case_vs_ctrl,Baseline,GOBP_MONONUCLEAR_CELL_DIFFERENTIATION,193,0.52,1.88,1.74E-10,5.60E-08,5.04E-08, case_vs_ctrl,Baseline,KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY,74,0.56,1.88,5.49E-06,0.000328266,0.000287728, case_vs_ctrl,Baseline,GOBP_LYMPHOCYTE_ACTIVATION,366,0.51,1.88,1.00E-10,3.72E-08,3.35E-08, case_vs_ctrl,Baseline,GOBP_IMMUNE_RESPONSE_REGULATING_SIGNALING_PATHWAY,229,0.52,1.87,1.00E-10,3.72E-08,3.35E-08, case_vs_ctrl,Baseline,GOBP_POSITIVE_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION,28,0.65,1.87,0.00021595,0.008118798,0.007306748, case_vs_ctrl,Baseline,GOBP_TOLL_LIKE_RECEPTOR_4_SIGNALING_PATHWAY,16,0.73,1.87,0.000328405,0.011053191,0.009947641, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_B_CELL_ACTIVATION,77,0.56,1.87,4.84E-06,0.00041223,0.000370998, case_vs_ctrl,Baseline,GOBP_PROTEIN_ADP_RIBOSYLATION,21,0.68,1.87,0.000606203,0.017632287,0.015868691, case_vs_ctrl,Baseline,REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM,62,0.58,1.87,1.70E-05,0.000663481,0.000581546, case_vs_ctrl,Baseline,GOBP_LEUKOCYTE_MEDIATED_CYTOTOXICITY,59,0.58,1.87,1.00E-05,0.000723693,0.000651308, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_B_CELL_PROLIFERATION,34,0.63,1.87,0.000275218,0.009775077,0.008797365, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION,34,0.63,1.86,0.000324265,0.01101878,0.009916673, case_vs_ctrl,Baseline,GOBP_NEGATIVE_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE,25,0.65,1.86,0.000497869,0.015396326,0.013856372, case_vs_ctrl,Baseline,GOBP_CELL_KILLING,74,0.56,1.86,1.53E-05,0.001038284,0.000934434, case_vs_ctrl,Baseline,HALLMARK_MYC_TARGETS_V1,163,0.52,1.86,4.66E-08,7.77E-07,5.56E-07, case_vs_ctrl,Baseline,GOBP_TOLERANCE_INDUCTION,13,0.75,1.85,0.000658448,0.0184679,0.016620725, case_vs_ctrl,Baseline,GOBP_IMMUNOGLOBULIN_PRODUCTION,64,0.57,1.85,1.68E-05,0.001130652,0.001017563, case_vs_ctrl,Baseline,GOBP_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE,153,0.52,1.85,8.95E-08,1.15E-05,1.04E-05, case_vs_ctrl,Baseline,GOBP_ACTIVATION_OF_IMMUNE_RESPONSE,171,0.52,1.84,1.03E-08,2.08E-06,1.87E-06, case_vs_ctrl,Baseline,GOBP_T_CELL_MEDIATED_IMMUNITY,47,0.59,1.84,4.58E-05,0.002655103,0.002389537, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_T_HELPER_CELL_DIFFERENTIATION,16,0.71,1.84,0.000635833,0.018121238,0.016308737, case_vs_ctrl,Baseline,GOBP_POSITIVE_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION,39,0.60,1.84,0.000200879,0.007675678,0.00690795, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION,30,0.62,1.83,0.000595259,0.017457635,0.015711508, case_vs_ctrl,Baseline,GOBP_NEGATIVE_REGULATION_OF_VIRAL_GENOME_REPLICATION,36,0.61,1.83,0.000681337,0.018959396,0.017063061, case_vs_ctrl,Baseline,REACTOME_RAC1_GTPASE_CYCLE,109,0.53,1.83,3.47E-06,0.00023941,0.000209845, case_vs_ctrl,Baseline,HALLMARK_MYC_TARGETS_V2,22,0.67,1.82,0.00053379,0.004448252,0.003184012, case_vs_ctrl,Baseline,GOBP_T_CELL_DIFFERENTIATION_INVOLVED_IN_IMMUNE_RESPONSE,33,0.61,1.82,0.000347726,0.011435918,0.010292088, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_LYMPHOCYTE_DIFFERENTIATION,85,0.54,1.82,6.92E-06,0.000514829,0.000463335, case_vs_ctrl,Baseline,GOBP_CELLULAR_DEFENSE_RESPONSE,20,0.67,1.82,0.001099463,0.027171346,0.024453645, case_vs_ctrl,Baseline,REACTOME_PD_1_SIGNALING,13,0.75,1.82,0.000484542,0.011138265,0.009762779, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_VIRAL_ENTRY_INTO_HOST_CELL,22,0.66,1.82,0.000946636,0.02381075,0.021429178, case_vs_ctrl,Baseline,REACTOME_DISEASES_OF_IMMUNE_SYSTEM,18,0.69,1.81,0.001135703,0.022133866,0.019400512, case_vs_ctrl,Baseline,GOBP_LEUKOCYTE_MEDIATED_IMMUNITY,185,0.51,1.81,2.07E-08,3.50E-06,3.15E-06, case_vs_ctrl,Baseline,KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION,31,-0.48,-1.81,0.002789096,0.040329424,0.035349065, case_vs_ctrl,Baseline,GOBP_HUMORAL_IMMUNE_RESPONSE,65,0.55,1.81,6.62E-05,0.003601501,0.003241276, case_vs_ctrl,Baseline,GOBP_POSITIVE_REGULATION_OF_LEUKOCYTE_CELL_CELL_ADHESION,127,0.52,1.81,8.96E-07,9.59E-05,8.63E-05, case_vs_ctrl,Baseline,GOBP_DOSAGE_COMPENSATION,15,0.71,1.80,0.00126362,0.030378454,0.027339976, case_vs_ctrl,Baseline,GOBP_RESPONSE_TO_INTERFERON_GAMMA,68,0.55,1.80,4.81E-05,0.002763697,0.00248727, case_vs_ctrl,Baseline,GOBP_MATURE_B_CELL_DIFFERENTIATION,15,0.71,1.80,0.001337227,0.031400391,0.028259697, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION,52,0.58,1.80,0.000108751,0.005090432,0.004581282, case_vs_ctrl,Baseline,GOBP_HOMOTYPIC_CELL_CELL_ADHESION,61,-0.40,-1.80,0.000414678,0.013383311,0.012044701, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE,90,0.54,1.80,1.46E-05,0.001008793,0.000907892, case_vs_ctrl,Baseline,REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA,200,0.50,1.79,5.35E-08,5.65E-06,4.95E-06, case_vs_ctrl,Baseline,GOBP_RETINA_HOMEOSTASIS,19,0.67,1.79,0.001436617,0.033401341,0.030060511, case_vs_ctrl,Baseline,GOBP_T_CELL_DIFFERENTIATION_IN_THYMUS,41,0.59,1.79,0.00061227,0.017678289,0.015910092, case_vs_ctrl,Baseline,GOBP_T_CELL_DIFFERENTIATION,119,0.52,1.79,4.99E-06,0.000419775,0.000377789, case_vs_ctrl,Baseline,GOBP_RNA_LOCALIZATION,137,0.51,1.78,6.25E-07,7.01E-05,6.31E-05, case_vs_ctrl,Baseline,GOBP_PEPTIDE_BIOSYNTHETIC_PROCESS,398,0.48,1.78,1.00E-10,3.72E-08,3.35E-08, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_BIOLOGICAL_PROCESS_INVOLVED_IN_SYMBIOTIC_INTERACTION,27,0.61,1.78,0.001704517,0.038303322,0.034472191, case_vs_ctrl,Baseline,GOBP_RNA_SPLICING_VIA_TRANSESTERIFICATION_REACTIONS,214,0.49,1.78,2.32E-08,3.81E-06,3.43E-06, case_vs_ctrl,Baseline,GOBP_RNA_SPLICING,294,0.49,1.78,1.96E-10,5.80E-08,5.22E-08, case_vs_ctrl,Baseline,REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES,63,0.55,1.77,0.000109256,0.00306088,0.002682886, case_vs_ctrl,Baseline,GOBP_VIRAL_RNA_GENOME_REPLICATION,27,0.61,1.77,0.001882765,0.041327273,0.037193684, case_vs_ctrl,Baseline,GOBP_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_EXOGENOUS_PEPTIDE_ANTIGEN_VIA_MHC_CLASS_II,15,0.70,1.77,0.002245048,0.047651654,0.042885495, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_PHAGOCYTOSIS,47,0.57,1.77,0.000251726,0.00903148,0.008128144, case_vs_ctrl,Baseline,GOBP_T_CELL_RECEPTOR_SIGNALING_PATHWAY,82,0.53,1.77,2.38E-05,0.001573358,0.001415989, case_vs_ctrl,Baseline,GOBP_ADAPTIVE_IMMUNE_RESPONSE,193,0.49,1.77,3.11E-08,4.57E-06,4.11E-06, case_vs_ctrl,Baseline,GOBP_POSITIVE_REGULATION_OF_INTERLEUKIN_1_PRODUCTION,27,0.61,1.77,0.002083294,0.044620365,0.040157398, case_vs_ctrl,Baseline,KEGG_HEMATOPOIETIC_CELL_LINEAGE,34,0.60,1.77,0.000530341,0.012036717,0.01055028, case_vs_ctrl,Baseline,GOBP_POSITIVE_REGULATION_OF_IMMUNE_RESPONSE,260,0.49,1.77,2.94E-09,6.70E-07,6.03E-07, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_VIRAL_GENOME_REPLICATION,57,0.55,1.76,0.000131624,0.005716679,0.005144892, case_vs_ctrl,Baseline,GOBP_LEUKOCYTE_PROLIFERATION,154,0.50,1.76,1.11E-06,0.000114613,0.000103149, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_LYMPHOCYTE_ACTIVATION,224,0.49,1.76,3.08E-08,4.57E-06,4.11E-06, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_T_CELL_DIFFERENTIATION,71,0.54,1.76,9.56E-05,0.004689017,0.004220017, case_vs_ctrl,Baseline,REACTOME_PURINERGIC_SIGNALING_IN_LEISHMANIASIS_INFECTION,17,0.68,1.76,0.002345417,0.036568113,0.032052246, case_vs_ctrl,Baseline,REACTOME_NUCLEAR_ENVELOPE_BREAKDOWN,35,0.59,1.76,0.0008646,0.018677452,0.016370938, case_vs_ctrl,Baseline,GOBP_ALPHA_BETA_T_CELL_ACTIVATION,76,0.53,1.76,0.000131836,0.005716679,0.005144892, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_LEUKOCYTE_PROLIFERATION,118,0.51,1.76,3.77E-06,0.000333299,0.000299962, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_T_CELL_MEDIATED_CYTOTOXICITY,18,0.67,1.76,0.001198708,0.029215399,0.02629325, case_vs_ctrl,Baseline,GOBP_NEGATIVE_REGULATION_OF_LYMPHOCYTE_ACTIVATION,70,0.53,1.76,0.000144471,0.006021906,0.00541959, case_vs_ctrl,Baseline,GOBP_VIRAL_TRANSLATION,17,0.67,1.75,0.002288187,0.04799082,0.043190737, case_vs_ctrl,Baseline,GOBP_ALPHA_BETA_T_CELL_DIFFERENTIATION,53,0.56,1.75,0.000347867,0.011435918,0.010292088, case_vs_ctrl,Baseline,GOBP_IMMUNE_EFFECTOR_PROCESS,278,0.48,1.75,2.49E-09,6.06E-07,5.45E-07, case_vs_ctrl,Baseline,GOBP_POSITIVE_REGULATION_OF_RESPONSE_TO_DNA_DAMAGE_STIMULUS,70,0.53,1.75,0.000181514,0.007229483,0.006506384, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_CHROMATIN_ASSEMBLY,24,0.62,1.75,0.002283633,0.04799082,0.043190737, case_vs_ctrl,Baseline,GOBP_LEUKOCYTE_DIFFERENTIATION,256,0.48,1.75,1.25E-08,2.46E-06,2.21E-06, case_vs_ctrl,Baseline,GOBP_MATURATION_OF_SSU_RRNA_FROM_TRICISTRONIC_RRNA_TRANSCRIPT_SSU_RRNA_5_8S_RRNA_LSU_RRNA,17,0.67,1.74,0.002555012,0.051303473,0.046172056, case_vs_ctrl,Baseline,HALLMARK_TNFA_SIGNALING_VIA_NFKB,89,0.52,1.74,8.13E-05,0.001015734,0.000727052, case_vs_ctrl,Baseline,REACTOME_INTERFERON_SIGNALING,125,0.50,1.74,1.58E-05,0.000643323,0.000563878, case_vs_ctrl,Baseline,KEGG_SPLICEOSOME,107,0.50,1.74,3.44E-05,0.00118543,0.001039039, case_vs_ctrl,Baseline,GOBP_THYMIC_T_CELL_SELECTION,14,0.70,1.74,0.002796554,0.054602329,0.049140957, case_vs_ctrl,Baseline,GOBP_POSITIVE_REGULATION_OF_HEMOPOIESIS,86,0.52,1.74,8.85E-05,0.004435375,0.003991745, case_vs_ctrl,Baseline,GOBP_POSITIVE_REGULATION_OF_CELL_CELL_ADHESION,139,0.50,1.74,1.20E-06,0.000119806,0.000107823, case_vs_ctrl,Baseline,GOBP_B_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE,46,0.56,1.74,0.000539615,0.016025212,0.014422357, case_vs_ctrl,Baseline,KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY,39,0.57,1.74,0.001336041,0.023939978,0.020983584, case_vs_ctrl,Baseline,GOBP_DEFENSE_RESPONSE_TO_SYMBIONT,143,0.49,1.74,5.80E-06,0.000476358,0.000428712, case_vs_ctrl,Baseline,REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION,178,-0.32,-1.74,1.29E-05,0.000578083,0.000506695, case_vs_ctrl,Baseline,GOBP_T_CELL_ACTIVATION,235,0.48,1.73,4.80E-08,6.66E-06,5.99E-06, case_vs_ctrl,Baseline,GOBP_CD4_POSITIVE_ALPHA_BETA_T_CELL_DIFFERENTIATION,37,0.57,1.73,0.001243587,0.03000399,0.027002966, case_vs_ctrl,Baseline,GOBP_MRNA_TRANSPORT,86,0.52,1.73,0.000111354,0.005144121,0.004629602, case_vs_ctrl,Baseline,REACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS,30,0.60,1.73,0.001186319,0.022628401,0.019833976, case_vs_ctrl,Baseline,GOBP_ESTABLISHMENT_OF_RNA_LOCALIZATION,109,0.50,1.73,2.23E-05,0.001489943,0.001340918, case_vs_ctrl,Baseline,GOBP_IMMUNOGLOBULIN_PRODUCTION_INVOLVED_IN_IMMUNOGLOBULIN_MEDIATED_IMMUNE_RESPONSE,40,0.57,1.73,0.00173897,0.038895687,0.035005308, case_vs_ctrl,Baseline,REACTOME_GENE_SILENCING_BY_RNA,52,0.55,1.72,0.000315036,0.007737797,0.006782242, case_vs_ctrl,Baseline,GOBP_VIRAL_GENOME_REPLICATION,90,0.51,1.72,0.000121799,0.005448572,0.004903601, case_vs_ctrl,Baseline,GOBP_B_CELL_MEDIATED_IMMUNITY,67,0.52,1.72,0.000498834,0.015396326,0.013856372, case_vs_ctrl,Baseline,REACTOME_POSTMITOTIC_NUCLEAR_PORE_COMPLEX_NPC_REFORMATION,21,0.64,1.72,0.002423544,0.036825553,0.032277894, case_vs_ctrl,Baseline,REACTOME_ANTIMICROBIAL_PEPTIDES,11,0.74,1.71,0.002257648,0.035822676,0.031398864, case_vs_ctrl,Baseline,GOBP_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_OR_POLYSACCHARIDE_ANTIGEN_VIA_MHC_CLASS_II,18,0.65,1.71,0.002433467,0.049424564,0.044481077, case_vs_ctrl,Baseline,GOBP_RNA_EXPORT_FROM_NUCLEUS,55,0.54,1.71,0.000444706,0.014222533,0.012799984, case_vs_ctrl,Baseline,GOBP_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY,59,0.53,1.71,0.000507681,0.015466771,0.013919771, case_vs_ctrl,Baseline,GOBP_MRNA_PROCESSING,328,0.47,1.71,2.80E-09,6.60E-07,5.94E-07, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_IMMUNE_RESPONSE,404,0.46,1.70,1.00E-10,3.72E-08,3.35E-08, case_vs_ctrl,Baseline,GOBP_NATURAL_KILLER_CELL_ACTIVATION,39,0.56,1.70,0.002041396,0.043989584,0.039589708, case_vs_ctrl,Baseline,GOBP_EXTERNAL_ENCAPSULATING_STRUCTURE_ORGANIZATION,68,-0.38,-1.70,0.000843576,0.021832804,0.019649069, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_LEUKOCYTE_MEDIATED_CYTOTOXICITY,33,0.57,1.70,0.001869204,0.041157416,0.037040816, case_vs_ctrl,Baseline,REACTOME_RAC2_GTPASE_CYCLE,61,0.53,1.70,0.00045717,0.010645525,0.009330889, case_vs_ctrl,Baseline,GOBP_CELLULAR_RESPONSE_TO_INTERLEUKIN_1,37,0.56,1.70,0.001914028,0.041862957,0.037675788, case_vs_ctrl,Baseline,GOBP_DEFENSE_RESPONSE_TO_OTHER_ORGANISM,441,0.46,1.70,1.00E-10,3.72E-08,3.35E-08, case_vs_ctrl,Baseline,GOBP_POSITIVE_REGULATION_OF_LEUKOCYTE_PROLIFERATION,76,0.51,1.70,0.000383839,0.012505063,0.011254296, case_vs_ctrl,Baseline,HALLMARK_KRAS_SIGNALING_UP,70,0.52,1.69,0.000921784,0.00658417,0.004712879, case_vs_ctrl,Baseline,GOBP_NEGATIVE_REGULATION_OF_VIRAL_PROCESS,53,0.54,1.69,0.001109409,0.027321616,0.024588884, case_vs_ctrl,Baseline,REACTOME_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_NLR_SIGNALING_PATHWAYS,45,0.55,1.69,0.000772765,0.016897158,0.014810495, case_vs_ctrl,Baseline,REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS,110,0.49,1.69,9.86E-05,0.00289899,0.002540988, case_vs_ctrl,Baseline,GOBP_SOMATIC_DIVERSIFICATION_OF_IMMUNE_RECEPTORS,47,0.55,1.69,0.001135452,0.027865874,0.025078706, case_vs_ctrl,Baseline,GOBP_INTERLEUKIN_2_PRODUCTION,32,0.57,1.68,0.002395887,0.049084426,0.04417496, case_vs_ctrl,Baseline,REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES,194,0.47,1.68,3.96E-06,0.000262655,0.000230219, case_vs_ctrl,Baseline,GOBP_AMIDE_BIOSYNTHETIC_PROCESS,461,0.45,1.68,1.00E-10,3.72E-08,3.35E-08, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION,135,0.48,1.68,4.07E-05,0.002437094,0.002193333, case_vs_ctrl,Baseline,REACTOME_ROS_AND_RNS_PRODUCTION_IN_PHAGOCYTES,23,0.61,1.68,0.003201431,0.044497412,0.03900234, case_vs_ctrl,Baseline,REACTOME_RAC3_GTPASE_CYCLE,64,0.52,1.68,0.001013574,0.020192645,0.017699016, case_vs_ctrl,Baseline,GOBP_POSITIVE_REGULATION_OF_LYMPHOCYTE_DIFFERENTIATION,57,0.53,1.68,0.00083111,0.021596649,0.019436534, case_vs_ctrl,Baseline,GOBP_POSITIVE_REGULATION_OF_CELL_ACTIVATION,189,0.47,1.68,3.16E-06,0.000286348,0.000257707, case_vs_ctrl,Baseline,GOBP_CELL_CELL_JUNCTION_ORGANIZATION,78,-0.35,-1.67,0.00178945,0.039773068,0.035794932, case_vs_ctrl,Baseline,GOBP_DEFENSE_RESPONSE_TO_BACTERIUM,79,0.50,1.67,0.00049677,0.015396326,0.013856372, case_vs_ctrl,Baseline,GOBP_LEUKOCYTE_CELL_CELL_ADHESION,183,0.47,1.67,5.24E-06,0.000435642,0.000392069, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_VIRAL_PROCESS,99,0.49,1.67,0.000144839,0.006021906,0.00541959, case_vs_ctrl,Baseline,GOBP_RNA_PHOSPHODIESTER_BOND_HYDROLYSIS,73,0.51,1.67,0.000474017,0.014956916,0.013460913, case_vs_ctrl,Baseline,GOBP_INNATE_IMMUNE_RESPONSE,353,0.45,1.66,5.44E-09,1.16E-06,1.05E-06, case_vs_ctrl,Baseline,REACTOME_MRNA_SPLICING,168,0.46,1.65,2.06E-05,0.000737057,0.000646037, case_vs_ctrl,Baseline,GOBP_RESPONSE_TO_VIRUS,202,0.46,1.65,6.89E-06,0.000514829,0.000463335, case_vs_ctrl,Baseline,GOBP_PHAGOCYTOSIS,127,0.47,1.65,8.24E-05,0.004160535,0.003744395, case_vs_ctrl,Baseline,GOBP_TELOMERE_MAINTENANCE,86,0.49,1.64,0.000718391,0.019680572,0.017712104, case_vs_ctrl,Baseline,REACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR,97,0.48,1.64,0.00045327,0.010645525,0.009330889, case_vs_ctrl,Baseline,GOBP_MRNA_METABOLIC_PROCESS,471,0.44,1.64,1.60E-10,5.38E-08,4.84E-08, case_vs_ctrl,Baseline,GOBP_CELLULAR_RESPONSE_TO_XENOBIOTIC_STIMULUS,48,0.53,1.64,0.002352486,0.048885334,0.043995782, case_vs_ctrl,Baseline,REACTOME_GLYCOLYSIS,49,0.52,1.64,0.002624048,0.038564909,0.033802453, case_vs_ctrl,Baseline,REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM,398,0.44,1.63,1.08E-08,1.21E-06,1.06E-06, case_vs_ctrl,Baseline,GOBP_PEPTIDE_METABOLIC_PROCESS,482,0.44,1.63,6.30E-10,1.71E-07,1.54E-07, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_INFLAMMATORY_RESPONSE,140,0.46,1.62,0.000148115,0.006122097,0.005509759, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_T_CELL_ACTIVATION,155,0.46,1.62,9.61E-05,0.004689017,0.004220017, case_vs_ctrl,Baseline,REACTOME_FCERI_MEDIATED_NF_KB_ACTIVATION,71,0.49,1.62,0.000901853,0.019023803,0.016674517, case_vs_ctrl,Baseline,REACTOME_SUMOYLATION,123,0.46,1.62,0.000299851,0.007467111,0.006544983, case_vs_ctrl,Baseline,GOBP_NEGATIVE_REGULATION_OF_CELLULAR_MACROMOLECULE_BIOSYNTHETIC_PROCESS,155,0.46,1.62,0.000100718,0.004842679,0.00435831, case_vs_ctrl,Baseline,KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION,58,-0.37,-1.62,0.002493912,0.037263197,0.032661493, case_vs_ctrl,Baseline,GOBP_NEGATIVE_REGULATION_OF_IMMUNE_RESPONSE,88,0.48,1.61,0.000806356,0.021108607,0.018997306, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY,114,0.47,1.61,0.000344129,0.011419279,0.010277113, case_vs_ctrl,Baseline,GOBP_RESPONSE_TO_BACTERIUM,228,0.45,1.61,1.04E-05,0.000745704,0.000671118, case_vs_ctrl,Baseline,GOBP_PROTEIN_LOCALIZATION_TO_CHROMOSOME,59,0.50,1.61,0.002423457,0.049363094,0.044425756, case_vs_ctrl,Baseline,REACTOME_C_TYPE_LECTIN_RECEPTORS_CLRS,102,0.47,1.61,0.001155309,0.022273864,0.019523221, case_vs_ctrl,Baseline,HALLMARK_INTERFERON_ALPHA_RESPONSE,71,0.49,1.61,0.001385986,0.007987477,0.005717352, case_vs_ctrl,Baseline,GOBP_NIK_NF_KAPPAB_SIGNALING,68,0.49,1.60,0.001919015,0.041862957,0.037675788, case_vs_ctrl,Baseline,GOBP_NUCLEAR_TRANSCRIBED_MRNA_CATABOLIC_PROCESS,88,0.48,1.60,0.001031348,0.025758198,0.023181842, case_vs_ctrl,Baseline,HALLMARK_COMPLEMENT,121,0.46,1.60,0.000532248,0.004448252,0.003184012, case_vs_ctrl,Baseline,GOBP_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY,89,0.48,1.60,0.000866848,0.022118696,0.019906366, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS,180,0.45,1.60,6.37E-05,0.0034896,0.003140567, case_vs_ctrl,Baseline,REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION,94,-0.33,-1.60,0.001703521,0.028545916,0.025020725, case_vs_ctrl,Baseline,REACTOME_TOLL_LIKE_RECEPTOR_CASCADES,107,0.46,1.60,0.000896662,0.019023803,0.016674517, case_vs_ctrl,Baseline,HALLMARK_IL2_STAT5_SIGNALING,96,0.47,1.60,0.001437746,0.007987477,0.005717352, case_vs_ctrl,Baseline,GOBP_INTERLEUKIN_6_PRODUCTION,65,0.49,1.60,0.002416234,0.049358205,0.044421355, case_vs_ctrl,Baseline,GOBP_NUCLEIC_ACID_PHOSPHODIESTER_BOND_HYDROLYSIS,118,0.46,1.60,0.000239208,0.008670374,0.007803156, case_vs_ctrl,Baseline,GOBP_TELOMERE_ORGANIZATION,90,0.47,1.59,0.001674254,0.037940344,0.034145518, case_vs_ctrl,Baseline,GOBP_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE,103,0.47,1.59,0.000729385,0.019757571,0.017781402, case_vs_ctrl,Baseline,REACTOME_FC_EPSILON_RECEPTOR_FCERI_SIGNALING,115,0.46,1.59,0.000942639,0.01950788,0.017098814, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_RESPONSE_TO_WOUNDING,67,-0.35,-1.59,0.002666016,0.053080009,0.047770901, case_vs_ctrl,Baseline,GOBP_POSITIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS,415,0.43,1.59,1.75E-08,3.18E-06,2.86E-06, case_vs_ctrl,Baseline,GOBP_CELLULAR_RESPONSE_TO_INTERFERON_GAMMA,55,0.50,1.59,0.002766035,0.054174967,0.048756341, case_vs_ctrl,Baseline,REACTOME_HCMV_EARLY_EVENTS,53,0.50,1.59,0.004257148,0.056125491,0.049194445, case_vs_ctrl,Baseline,GOBP_TRANSLATIONAL_INITIATION,93,0.47,1.58,0.001524224,0.03520658,0.031685188, case_vs_ctrl,Baseline,REACTOME_INTERLEUKIN_1_FAMILY_SIGNALING,101,0.46,1.58,0.001212281,0.022880214,0.020054692, case_vs_ctrl,Baseline,REACTOME_CLEC7A_DECTIN_1_SIGNALING,87,0.46,1.58,0.002066274,0.033376841,0.02925507, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_INNATE_IMMUNE_RESPONSE,125,0.45,1.57,0.000612787,0.017678289,0.015910092, case_vs_ctrl,Baseline,GOBP_POSITIVE_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS,118,0.45,1.57,0.000442885,0.014222533,0.012799984, case_vs_ctrl,Baseline,GOBP_POSITIVE_REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING,109,0.46,1.57,0.000819086,0.021362739,0.019226019, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_CELL_CELL_ADHESION,205,0.43,1.57,6.10E-05,0.003366186,0.003029497, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS,162,0.44,1.57,0.000219818,0.008220487,0.007398267, case_vs_ctrl,Baseline,GOBP_RESPONSE_TO_CYTOKINE,413,0.42,1.57,1.11E-07,1.35E-05,1.21E-05, case_vs_ctrl,Baseline,GOBP_RNA_CATABOLIC_PROCESS,183,0.44,1.56,0.000115329,0.005194164,0.004674639, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION,147,0.44,1.56,0.000185435,0.007292214,0.006562841, case_vs_ctrl,Baseline,GOBP_POSITIVE_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS,88,0.46,1.55,0.002388742,0.049084426,0.04417496, case_vs_ctrl,Baseline,GOBP_NUCLEOBASE_CONTAINING_COMPOUND_TRANSPORT,131,0.45,1.55,0.000536229,0.015991832,0.014392315, case_vs_ctrl,Baseline,GOBP_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING,155,0.44,1.55,0.000490648,0.015396326,0.013856372, case_vs_ctrl,Baseline,HALLMARK_IL6_JAK_STAT3_SIGNALING,37,0.52,1.55,0.012290471,0.047271041,0.033836114, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_RESPONSE_TO_DNA_DAMAGE_STIMULUS,136,0.44,1.54,0.00080479,0.021108607,0.018997306, case_vs_ctrl,Baseline,GOBP_POSITIVE_REGULATION_OF_CYTOKINE_PRODUCTION,208,0.43,1.54,0.000182067,0.007229483,0.006506384, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_HEMOPOIESIS,182,0.43,1.54,0.00044734,0.014242342,0.012817811, case_vs_ctrl,Baseline,GOBP_MYELOID_LEUKOCYTE_ACTIVATION,107,0.45,1.54,0.001804067,0.039972243,0.035974185, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_RNA_SPLICING,111,0.45,1.53,0.002722612,0.053903151,0.048511712, case_vs_ctrl,Baseline,GOBP_VIRAL_PROCESS,263,0.42,1.53,7.20E-05,0.003854842,0.003469277, case_vs_ctrl,Baseline,REACTOME_RHOA_GTPASE_CYCLE,87,0.45,1.52,0.004152955,0.055157398,0.048345903, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_DEFENSE_RESPONSE,274,0.42,1.52,7.98E-05,0.004089593,0.003680549, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_BODY_FLUID_LEVELS,189,-0.28,-1.52,0.000231381,0.008562312,0.007705902, case_vs_ctrl,Baseline,GOBP_VIRAL_LIFE_CYCLE,188,0.42,1.52,0.000506756,0.015466771,0.013919771, case_vs_ctrl,Baseline,GOBP_MRNA_CATABOLIC_PROCESS,156,0.43,1.51,0.000855993,0.021920864,0.01972832, case_vs_ctrl,Baseline,GOBP_CELLULAR_NITROGEN_COMPOUND_CATABOLIC_PROCESS,251,0.41,1.50,0.000153809,0.006283957,0.00565543, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_CELL_ACTIVATION,297,0.41,1.50,5.26E-05,0.002976222,0.002678538, case_vs_ctrl,Baseline,REACTOME_SIGNALING_BY_INTERLEUKINS,254,0.41,1.50,0.000147121,0.003879241,0.003400186, case_vs_ctrl,Baseline,REACTOME_CELLULAR_RESPONSES_TO_STIMULI,500,0.40,1.50,5.75E-07,5.15E-05,4.52E-05, case_vs_ctrl,Baseline,GOBP_HEMOSTASIS,139,-0.30,-1.49,0.000657417,0.0184679,0.016620725, case_vs_ctrl,Baseline,GOBP_T_CELL_PROLIFERATION,100,0.44,1.49,0.002285412,0.04799082,0.043190737, case_vs_ctrl,Baseline,HALLMARK_COAGULATION,55,-0.34,-1.48,0.018003369,0.060011231,0.042955407, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_CELLULAR_AMIDE_METABOLIC_PROCESS,282,0.40,1.47,0.000198783,0.007675678,0.00690795, case_vs_ctrl,Baseline,HALLMARK_APOPTOSIS,105,0.43,1.47,0.006091661,0.030458306,0.021801735, case_vs_ctrl,Baseline,GOBP_IMMUNE_SYSTEM_DEVELOPMENT,464,0.39,1.46,7.58E-06,0.000558065,0.000502247, case_vs_ctrl,Baseline,GOBP_CYTOKINE_PRODUCTION,330,0.40,1.46,0.000114727,0.005194164,0.004674639, case_vs_ctrl,Baseline,REACTOME_NEUTROPHIL_DEGRANULATION,300,0.40,1.46,0.000349303,0.008350679,0.007319437, case_vs_ctrl,Baseline,GOBP_POSTTRANSCRIPTIONAL_REGULATION_OF_GENE_EXPRESSION,329,0.40,1.45,0.000189696,0.007407573,0.006666661, case_vs_ctrl,Baseline,GOBP_ORGANIC_CYCLIC_COMPOUND_CATABOLIC_PROCESS,263,0.40,1.45,0.000750195,0.020082773,0.018074077, case_vs_ctrl,Baseline,GOBP_POSITIVE_REGULATION_OF_CELL_DEATH,296,0.39,1.44,0.000285666,0.009995464,0.00899571, case_vs_ctrl,Baseline,GOBP_POSITIVE_REGULATION_OF_CELL_ADHESION,210,0.40,1.44,0.001605135,0.036761025,0.033084156, case_vs_ctrl,Baseline,HALLMARK_FATTY_ACID_METABOLISM,91,0.43,1.43,0.010331598,0.043048326,0.030813539, case_vs_ctrl,Baseline,HALLMARK_E2F_TARGETS,115,0.41,1.42,0.008198807,0.037267306,0.026675546, case_vs_ctrl,Baseline,GOBP_INFLAMMATORY_RESPONSE,293,0.39,1.41,0.00055578,0.016436201,0.014792238, case_vs_ctrl,Baseline,REACTOME_RHO_GTPASE_CYCLE,271,0.38,1.37,0.003185619,0.044497412,0.03900234, case_vs_ctrl,Baseline,HALLMARK_MYOGENESIS,76,-0.29,-1.36,0.015880869,0.056717391,0.040597711, case_vs_ctrl,Baseline,GOBP_CELL_CELL_ADHESION,350,0.37,1.36,0.001612326,0.036761025,0.033084156, case_vs_ctrl,Baseline,GOBP_REGULATION_OF_CELLULAR_MACROMOLECULE_BIOSYNTHETIC_PROCESS,407,0.37,1.35,0.000774698,0.020507728,0.018456528, case_vs_ctrl,Baseline,GOBP_DNA_METABOLIC_PROCESS,459,0.36,1.33,0.001612326,0.036761025,0.033084156, case_vs_ctrl,Baseline,REACTOME_ADAPTIVE_IMMUNE_SYSTEM,462,0.35,1.28,0.003089347,0.043615739,0.038229547, case_vs_ctrl,postCPET,REACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM,14,-0.75,-2.21,0.000140849,0.014030094,0.013565952, case_vs_ctrl,postCPET,REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION,79,0.61,2.18,7.43E-09,3.06E-06,2.96E-06, case_vs_ctrl,postCPET,REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY,84,0.61,2.17,8.54E-09,3.06E-06,2.96E-06, case_vs_ctrl,postCPET,KEGG_RIBOSOME,76,0.61,2.17,2.89E-08,8.63E-06,8.35E-06, case_vs_ctrl,postCPET,REACTOME_ECM_PROTEOGLYCANS,20,-0.68,-2.16,0.000156251,0.014745169,0.014257372, case_vs_ctrl,postCPET,GOBP_PROTEOGLYCAN_METABOLIC_PROCESS,21,-0.68,-2.15,9.95E-05,0.04627511,0.045509618, case_vs_ctrl,postCPET,REACTOME_EUKARYOTIC_TRANSLATION_INITIATION,103,0.58,2.15,7.28E-09,3.06E-06,2.96E-06, case_vs_ctrl,postCPET,REACTOME_SELENOAMINO_ACID_METABOLISM,84,0.59,2.13,3.77E-08,9.65E-06,9.33E-06, case_vs_ctrl,postCPET,GOBP_POSITIVE_REGULATION_OF_MUSCLE_CONTRACTION,15,-0.73,-2.10,0.000104011,0.04627511,0.045509618, case_vs_ctrl,postCPET,REACTOME_PLATELET_AGGREGATION_PLUG_FORMATION,23,-0.63,-2.07,0.000198521,0.016949892,0.016389158, case_vs_ctrl,postCPET,REACTOME_RRNA_PROCESSING,139,0.54,2.07,2.52E-09,2.26E-06,2.19E-06, case_vs_ctrl,postCPET,REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION,94,-0.45,-2.01,5.59E-06,0.000933164,0.000902293, case_vs_ctrl,postCPET,REACTOME_NONSENSE_MEDIATED_DECAY_NMD,101,0.53,1.94,3.46E-06,0.000776173,0.000750495, case_vs_ctrl,postCPET,REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE,96,0.52,1.91,9.34E-06,0.001116874,0.001079926, case_vs_ctrl,postCPET,HALLMARK_COAGULATION,55,-0.46,-1.89,0.000538088,0.026904396,0.026054784, case_vs_ctrl,postCPET,GOBP_RIBOSOME_BIOGENESIS,158,0.48,1.89,1.41E-06,0.003491634,0.003433875, case_vs_ctrl,postCPET,GOBP_RRNA_METABOLIC_PROCESS,139,0.49,1.88,2.61E-06,0.004618196,0.004541801, case_vs_ctrl,postCPET,REACTOME_CELLULAR_RESPONSE_TO_STARVATION,118,0.50,1.88,4.71E-06,0.000933164,0.000902293, case_vs_ctrl,postCPET,GOBP_CYTOPLASMIC_TRANSLATION,119,0.49,1.87,3.64E-06,0.005151258,0.005066044, case_vs_ctrl,postCPET,REACTOME_INFLUENZA_INFECTION,131,0.49,1.87,7.61E-06,0.001116874,0.001079926, case_vs_ctrl,postCPET,REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2,89,-0.42,-1.86,0.000110341,0.01163776,0.011252761, case_vs_ctrl,postCPET,REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS,141,0.48,1.83,9.25E-06,0.001116874,0.001079926, case_vs_ctrl,postCPET,REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S,54,0.55,1.83,0.000173101,0.015518526,0.015005144, case_vs_ctrl,postCPET,REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION,178,-0.36,-1.78,5.72E-06,0.000933164,0.000902293, case_vs_ctrl,postCPET,REACTOME_TRANSLATION,189,0.44,1.75,9.02E-06,0.001116874,0.001079926, case_vs_ctrl,postCPET,GOBP_RIBONUCLEOPROTEIN_COMPLEX_BIOGENESIS,248,0.42,1.72,6.95E-06,0.007024602,0.0069084, case_vs_ctrl,postCPET,GOBP_NCRNA_METABOLIC_PROCESS,236,0.40,1.64,7.28E-05,0.042900895,0.04219122, case_vs_ctrl,postCPET,REACTOME_SIGNALING_BY_ROBO_RECEPTORS,165,0.41,1.62,0.00035613,0.027762665,0.026844225, case_vs_ctrl,postCPET,REACTOME_METABOLISM_OF_RNA,477,0.36,1.50,2.15E-05,0.002408382,0.002328708, postCPET_vs_Baseline,Case,REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION,79,-0.66,-2.19,1.24E-10,3.89E-08,3.39E-08, postCPET_vs_Baseline,Case,KEGG_RIBOSOME,76,-0.66,-2.19,1.52E-10,3.89E-08,3.39E-08, postCPET_vs_Baseline,Case,REACTOME_EUKARYOTIC_TRANSLATION_INITIATION,103,-0.64,-2.18,1.00E-10,3.89E-08,3.39E-08, postCPET_vs_Baseline,Case,GOBP_CYTOPLASMIC_TRANSLATION,119,-0.63,-2.16,1.00E-10,3.22E-08,2.80E-08, postCPET_vs_Baseline,Case,REACTOME_RRNA_PROCESSING,139,-0.62,-2.16,1.00E-10,3.89E-08,3.39E-08, postCPET_vs_Baseline,Case,GOBP_CELL_COMMUNICATION_INVOLVED_IN_CARDIAC_CONDUCTION,18,0.67,2.14,0.000276293,0.009170989,0.007982425, postCPET_vs_Baseline,Case,REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY,84,-0.64,-2.13,2.12E-10,4.75E-08,4.14E-08, postCPET_vs_Baseline,Case,GOBP_B_CELL_ACTIVATION,146,-0.60,-2.10,1.00E-10,3.22E-08,2.80E-08, postCPET_vs_Baseline,Case,GOBP_CELL_COMMUNICATION_BY_ELECTRICAL_COUPLING,16,0.66,2.09,0.001573211,0.035565626,0.030956306, postCPET_vs_Baseline,Case,HALLMARK_ALLOGRAFT_REJECTION,101,-0.62,-2.08,1.00E-10,3.57E-09,2.48E-09, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_B_CELL_ACTIVATION,77,-0.62,-2.06,2.23E-08,3.59E-06,3.12E-06, postCPET_vs_Baseline,Case,GOBP_CELL_COMMUNICATION_BY_ELECTRICAL_COUPLING_INVOLVED_IN_CARDIAC_CONDUCTION,14,0.69,2.05,0.001290528,0.030541053,0.026582919, postCPET_vs_Baseline,Case,REACTOME_INFLUENZA_INFECTION,131,-0.59,-2.05,1.48E-10,3.89E-08,3.39E-08, postCPET_vs_Baseline,Case,HALLMARK_INTERFERON_GAMMA_RESPONSE,132,-0.59,-2.05,1.43E-10,3.57E-09,2.48E-09, postCPET_vs_Baseline,Case,REACTOME_CELLULAR_RESPONSE_TO_STARVATION,118,-0.59,-2.04,3.91E-10,7.01E-08,6.11E-08, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_LYMPHOCYTE_DIFFERENTIATION,85,-0.61,-2.04,2.96E-08,4.45E-06,3.88E-06, postCPET_vs_Baseline,Case,GOBP_RRNA_METABOLIC_PROCESS,139,-0.58,-2.03,1.00E-10,3.22E-08,2.80E-08, postCPET_vs_Baseline,Case,REACTOME_TRANSLATION,189,-0.57,-2.02,1.00E-10,3.89E-08,3.39E-08, postCPET_vs_Baseline,Case,REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE,96,-0.60,-2.02,3.90E-09,5.37E-07,4.68E-07, postCPET_vs_Baseline,Case,GOBP_RIBOSOME_BIOGENESIS,158,-0.57,-2.02,1.00E-10,3.22E-08,2.80E-08, postCPET_vs_Baseline,Case,REACTOME_NONSENSE_MEDIATED_DECAY_NMD,101,-0.60,-2.02,8.07E-09,1.03E-06,9.01E-07, postCPET_vs_Baseline,Case,GOBP_POSITIVE_REGULATION_OF_MYELOID_LEUKOCYTE_DIFFERENTIATION,30,-0.69,-2.02,2.19E-05,0.001315299,0.001144836, postCPET_vs_Baseline,Case,GOBP_B_CELL_PROLIFERATION,43,-0.66,-2.02,1.57E-06,0.000137572,0.000119742, postCPET_vs_Baseline,Case,REACTOME_SELENOAMINO_ACID_METABOLISM,84,-0.61,-2.01,2.95E-08,3.53E-06,3.07E-06, postCPET_vs_Baseline,Case,GOBP_B_CELL_DIFFERENTIATION,67,-0.62,-2.01,4.68E-07,4.87E-05,4.24E-05, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION,135,-0.58,-2.01,2.51E-10,6.58E-08,5.73E-08, postCPET_vs_Baseline,Case,GOBP_POSITIVE_REGULATION_OF_HEMOPOIESIS,86,-0.60,-2.00,9.03E-08,1.21E-05,1.05E-05, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_T_CELL_DIFFERENTIATION,71,-0.61,-2.00,4.48E-07,4.82E-05,4.20E-05, postCPET_vs_Baseline,Case,GOBP_RIBONUCLEOPROTEIN_COMPLEX_BIOGENESIS,248,-0.56,-2.00,1.00E-10,3.22E-08,2.80E-08, postCPET_vs_Baseline,Case,REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S,54,-0.63,-1.99,1.75E-06,0.000130899,0.000114042, postCPET_vs_Baseline,Case,REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS,141,-0.57,-1.98,4.78E-10,7.80E-08,6.79E-08, postCPET_vs_Baseline,Case,GOBP_HUMORAL_IMMUNE_RESPONSE,65,-0.61,-1.98,1.87E-06,0.00015909,0.000138472, postCPET_vs_Baseline,Case,GOBP_LYMPHOCYTE_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE,99,-0.58,-1.97,1.61E-07,1.97E-05,1.71E-05, postCPET_vs_Baseline,Case,GOBP_NCRNA_PROCESSING,183,-0.55,-1.96,1.00E-10,3.22E-08,2.80E-08, postCPET_vs_Baseline,Case,GOBP_DEFENSE_RESPONSE_TO_BACTERIUM,79,-0.59,-1.96,3.06E-07,3.49E-05,3.04E-05, postCPET_vs_Baseline,Case,GOBP_POSITIVE_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION,39,-0.65,-1.95,7.32E-06,0.000544969,0.000474341, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_VIRAL_ENTRY_INTO_HOST_CELL,22,-0.72,-1.95,0.000133317,0.005211897,0.004536433, postCPET_vs_Baseline,Case,GOBP_POSITIVE_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_DIFFERENTIATION,15,-0.79,-1.94,2.75E-05,0.001531742,0.001333228, postCPET_vs_Baseline,Case,GOBP_MONONUCLEAR_CELL_DIFFERENTIATION,193,-0.54,-1.94,1.00E-10,3.22E-08,2.80E-08, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_SUPEROXIDE_ANION_GENERATION,13,-0.82,-1.94,7.70E-05,0.003425276,0.002981359, postCPET_vs_Baseline,Case,GOBP_RIBOSOME_ASSEMBLY,35,-0.66,-1.94,3.76E-05,0.001912447,0.001664593, postCPET_vs_Baseline,Case,KEGG_LEISHMANIA_INFECTION,42,-0.64,-1.94,2.09E-05,0.001294701,0.001127975, postCPET_vs_Baseline,Case,REACTOME_SIGNALING_BY_ROBO_RECEPTORS,165,-0.55,-1.94,1.20E-09,1.79E-07,1.56E-07, postCPET_vs_Baseline,Case,GOBP_RIBONUCLEOPROTEIN_COMPLEX_SUBUNIT_ORGANIZATION,126,-0.56,-1.93,3.83E-08,5.53E-06,4.82E-06, postCPET_vs_Baseline,Case,GOBP_RIBOSOMAL_SMALL_SUBUNIT_BIOGENESIS,42,-0.64,-1.93,1.71E-05,0.001080185,0.000940193, postCPET_vs_Baseline,Case,REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES,22,-0.71,-1.92,0.000179175,0.00698392,0.006084561, postCPET_vs_Baseline,Case,GOBP_LYMPHOCYTE_ACTIVATION,366,-0.52,-1.91,1.00E-10,3.22E-08,2.80E-08, postCPET_vs_Baseline,Case,GOBP_RIBOSOMAL_LARGE_SUBUNIT_BIOGENESIS,36,-0.64,-1.90,8.08E-05,0.003499733,0.003046167, postCPET_vs_Baseline,Case,GOBP_RESPIRATORY_BURST,23,-0.70,-1.90,0.00014827,0.005609044,0.00488211, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_DIFFERENTIATION,24,-0.69,-1.90,0.000182322,0.006738893,0.00586553, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_PLATELET_ACTIVATION,32,0.50,1.90,0.001956776,0.041086494,0.035761667, postCPET_vs_Baseline,Case,GOBP_T_CELL_DIFFERENTIATION,119,-0.55,-1.89,2.19E-07,2.58E-05,2.25E-05, postCPET_vs_Baseline,Case,GOBP_LEUKOCYTE_DIFFERENTIATION,256,-0.52,-1.89,1.00E-10,3.22E-08,2.80E-08, postCPET_vs_Baseline,Case,GOBP_RESPONSE_TO_TUMOR_CELL,19,-0.73,-1.89,0.000201837,0.007140986,0.006215511, postCPET_vs_Baseline,Case,HALLMARK_INTERFERON_ALPHA_RESPONSE,71,-0.59,-1.89,6.65E-06,8.31E-05,5.77E-05, postCPET_vs_Baseline,Case,REACTOME_METABOLISM_OF_RNA,477,-0.52,-1.89,1.00E-10,3.89E-08,3.39E-08, postCPET_vs_Baseline,Case,GOBP_T_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE,47,-0.62,-1.89,1.35E-05,0.000910761,0.000792726, postCPET_vs_Baseline,Case,GOBP_NATURAL_KILLER_CELL_ACTIVATION,39,-0.63,-1.88,3.79E-05,0.001916833,0.00166841, postCPET_vs_Baseline,Case,KEGG_PRIMARY_IMMUNODEFICIENCY,16,-0.75,-1.88,0.000123651,0.005407479,0.004711128, postCPET_vs_Baseline,Case,GOBP_POSITIVE_REGULATION_OF_LYMPHOCYTE_DIFFERENTIATION,57,-0.59,-1.88,1.29E-05,0.000891834,0.000776252, postCPET_vs_Baseline,Case,REACTOME_RRNA_MODIFICATION_IN_THE_NUCLEUS_AND_CYTOSOL,40,-0.62,-1.88,9.70E-05,0.004457565,0.003883539, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_LYMPHOCYTE_ACTIVATION,224,-0.52,-1.88,1.36E-10,4.07E-08,3.54E-08, postCPET_vs_Baseline,Case,GOBP_POSITIVE_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION,28,-0.66,-1.87,0.000240453,0.008102107,0.00705207, postCPET_vs_Baseline,Case,GOBP_CELLULAR_DEFENSE_RESPONSE,20,-0.71,-1.87,0.000303501,0.009851988,0.008575167, postCPET_vs_Baseline,Case,GOBP_SUPEROXIDE_METABOLIC_PROCESS,35,-0.64,-1.87,0.000149025,0.005609044,0.00488211, postCPET_vs_Baseline,Case,GOBP_ADAPTIVE_IMMUNE_RESPONSE_BASED_ON_SOMATIC_RECOMBINATION_OF_IMMUNE_RECEPTORS_BUILT_FROM_IMMUNOGLOBULIN_SUPERFAMILY_DOMAINS,135,-0.54,-1.87,1.39E-07,1.75E-05,1.53E-05, postCPET_vs_Baseline,Case,GOBP_B_CELL_MEDIATED_IMMUNITY,67,-0.57,-1.87,2.99E-05,0.00164039,0.001427795, postCPET_vs_Baseline,Case,GOBP_IMMUNE_RESPONSE_REGULATING_SIGNALING_PATHWAY,229,-0.52,-1.86,2.41E-10,6.56E-08,5.71E-08, postCPET_vs_Baseline,Case,REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL,39,-0.62,-1.86,9.14E-05,0.004378769,0.00381489, postCPET_vs_Baseline,Case,GOBP_IMMUNE_RESPONSE_REGULATING_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY,152,-0.53,-1.86,5.37E-08,7.60E-06,6.62E-06, postCPET_vs_Baseline,Case,GOBP_NCRNA_METABOLIC_PROCESS,236,-0.52,-1.85,1.44E-10,4.07E-08,3.54E-08, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_BIOLOGICAL_PROCESS_INVOLVED_IN_SYMBIOTIC_INTERACTION,27,-0.66,-1.85,0.000414421,0.012480015,0.0108626, postCPET_vs_Baseline,Case,GOBP_ALPHA_BETA_T_CELL_ACTIVATION,76,-0.56,-1.85,1.27E-05,0.000891834,0.000776252, postCPET_vs_Baseline,Case,GOBP_RESPONSE_TO_PROTOZOAN,12,-0.79,-1.85,0.000487563,0.014024364,0.0122068, postCPET_vs_Baseline,Case,GOBP_DEFENSE_RESPONSE_TO_GRAM_POSITIVE_BACTERIUM,26,-0.66,-1.85,0.000303524,0.009851988,0.008575167, postCPET_vs_Baseline,Case,GOBP_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE,153,-0.53,-1.84,1.31E-07,1.68E-05,1.46E-05, postCPET_vs_Baseline,Case,GOBP_LEUKOCYTE_MEDIATED_CYTOTOXICITY,59,-0.58,-1.84,8.11E-05,0.003499733,0.003046167, postCPET_vs_Baseline,Case,GOBP_POSITIVE_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION,18,-0.71,-1.84,0.000484695,0.013998787,0.012184538, postCPET_vs_Baseline,Case,REACTOME_DISEASES_OF_IMMUNE_SYSTEM,18,-0.72,-1.84,0.000235776,0.00862749,0.007516479, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_SUPEROXIDE_METABOLIC_PROCESS,18,-0.71,-1.84,0.000484695,0.013998787,0.012184538, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_B_CELL_PROLIFERATION,34,-0.62,-1.84,0.000282015,0.009238614,0.008041286, postCPET_vs_Baseline,Case,REACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS,22,0.55,1.83,0.003432869,0.056108583,0.048883164, postCPET_vs_Baseline,Case,GOBP_POSITIVE_REGULATION_OF_B_CELL_ACTIVATION,48,-0.60,-1.83,0.00010891,0.004364825,0.003799142, postCPET_vs_Baseline,Case,REACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS,43,-0.60,-1.83,0.000201649,0.007692689,0.006702058, postCPET_vs_Baseline,Case,GOBP_PEPTIDE_BIOSYNTHETIC_PROCESS,398,-0.50,-1.83,1.00E-10,3.22E-08,2.80E-08, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_HEMOPOIESIS,182,-0.51,-1.83,6.24E-08,8.57E-06,7.46E-06, postCPET_vs_Baseline,Case,GOBP_LYMPHOCYTE_MEDIATED_IMMUNITY,129,-0.53,-1.83,8.50E-07,7.81E-05,6.80E-05, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION,52,-0.59,-1.83,7.93E-05,0.003487168,0.00303523, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_MYELOID_LEUKOCYTE_DIFFERENTIATION,57,-0.57,-1.82,4.57E-05,0.002214886,0.001927836, postCPET_vs_Baseline,Case,GOBP_IMMUNOGLOBULIN_PRODUCTION,64,-0.57,-1.82,0.000113426,0.004509002,0.003924634, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_MONOCYTE_DIFFERENTIATION,12,-0.78,-1.82,0.0008221,0.021787202,0.018963571, postCPET_vs_Baseline,Case,GOBP_SUPEROXIDE_ANION_GENERATION,22,-0.68,-1.82,0.001295816,0.030563973,0.026602869, postCPET_vs_Baseline,Case,GOBP_MATURATION_OF_SSU_RRNA_FROM_TRICISTRONIC_RRNA_TRANSCRIPT_SSU_RRNA_5_8S_RRNA_LSU_RRNA,17,-0.72,-1.82,0.000994932,0.02546191,0.022162035, postCPET_vs_Baseline,Case,REACTOME_INTERFERON_GAMMA_SIGNALING,52,-0.58,-1.82,9.28E-05,0.004378769,0.00381489, postCPET_vs_Baseline,Case,REACTOME_INTERFERON_ALPHA_BETA_SIGNALING,41,-0.60,-1.81,0.000147322,0.006003365,0.005230278, postCPET_vs_Baseline,Case,GOBP_ANTIGEN_RECEPTOR_MEDIATED_SIGNALING_PATHWAY,115,-0.52,-1.81,4.66E-06,0.000366296,0.000318823, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION,34,-0.61,-1.80,0.000577822,0.016354667,0.014235095, postCPET_vs_Baseline,Case,REACTOME_TCR_SIGNALING,98,-0.53,-1.80,1.32E-05,0.000843875,0.000735204, postCPET_vs_Baseline,Case,GOBP_PHAGOCYTOSIS,127,-0.52,-1.79,5.60E-06,0.000430553,0.000374753, postCPET_vs_Baseline,Case,GOBP_RESPONSE_TO_BACTERIUM,228,-0.50,-1.79,2.19E-08,3.59E-06,3.12E-06, postCPET_vs_Baseline,Case,REACTOME_PURINERGIC_SIGNALING_IN_LEISHMANIASIS_INFECTION,17,-0.70,-1.79,0.000792071,0.022190353,0.019332776, postCPET_vs_Baseline,Case,GOBP_POSITIVE_REGULATION_OF_PHAGOCYTOSIS,31,-0.61,-1.79,0.001073681,0.02713344,0.023616935, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_DNA_RECOMBINATION,69,-0.55,-1.79,3.45E-05,0.001783504,0.001552361, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_LEUKOCYTE_MEDIATED_CYTOTOXICITY,33,-0.61,-1.79,0.00094328,0.02453915,0.021358865, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE,90,-0.53,-1.78,5.51E-05,0.002599165,0.002262312, postCPET_vs_Baseline,Case,REACTOME_INTERFERON_SIGNALING,125,-0.52,-1.78,1.71E-06,0.000130899,0.000114042, postCPET_vs_Baseline,Case,GOBP_CELL_KILLING,74,-0.54,-1.77,9.82E-05,0.004101993,0.003570373, postCPET_vs_Baseline,Case,GOBP_HOMOTYPIC_CELL_CELL_ADHESION,61,0.43,1.77,0.000194936,0.007001855,0.006094412, postCPET_vs_Baseline,Case,GOBP_DEFENSE_RESPONSE_TO_OTHER_ORGANISM,441,-0.48,-1.77,1.00E-10,3.22E-08,2.80E-08, postCPET_vs_Baseline,Case,GOBP_POSITIVE_REGULATION_OF_ALPHA_BETA_T_CELL_PROLIFERATION,16,-0.71,-1.77,0.001657893,0.037083795,0.032277719, postCPET_vs_Baseline,Case,GOBP_RNA_PHOSPHODIESTER_BOND_HYDROLYSIS_ENDONUCLEOLYTIC,30,-0.61,-1.77,0.001692469,0.037424715,0.032574456, postCPET_vs_Baseline,Case,GOBP_B_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE,46,-0.58,-1.76,0.000407083,0.012378025,0.010773828, postCPET_vs_Baseline,Case,GOBP_ALPHA_BETA_T_CELL_PROLIFERATION,27,-0.62,-1.76,0.00208973,0.042985267,0.037414358, postCPET_vs_Baseline,Case,REACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS,34,-0.60,-1.76,0.000961872,0.024942494,0.021730508, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_IMMUNE_RESPONSE,404,-0.48,-1.76,1.00E-10,3.22E-08,2.80E-08, postCPET_vs_Baseline,Case,GOBP_CELLULAR_RESPONSE_TO_XENOBIOTIC_STIMULUS,48,-0.57,-1.76,0.00042376,0.012651996,0.011012292, postCPET_vs_Baseline,Case,GOBP_NEGATIVE_REGULATION_OF_IMMUNE_RESPONSE,88,-0.52,-1.76,0.000102269,0.00423189,0.003683435, postCPET_vs_Baseline,Case,REACTOME_TRAF6_MEDIATED_NF_KB_ACTIVATION,20,-0.67,-1.76,0.00200289,0.040808892,0.0355537, postCPET_vs_Baseline,Case,GOBP_POSITIVE_REGULATION_OF_LEUKOCYTE_CELL_CELL_ADHESION,127,-0.51,-1.76,1.37E-05,0.000915814,0.000797124, postCPET_vs_Baseline,Case,GOBP_T_CELL_ACTIVATION,235,-0.49,-1.76,1.11E-08,1.91E-06,1.66E-06, postCPET_vs_Baseline,Case,HALLMARK_MYC_TARGETS_V1,163,-0.50,-1.76,7.38E-07,1.23E-05,8.54E-06, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_VIRAL_PROCESS,99,-0.52,-1.76,6.58E-05,0.003044055,0.002649544, postCPET_vs_Baseline,Case,GOBP_POSITIVE_REGULATION_OF_CELL_ACTIVATION,189,-0.49,-1.76,8.00E-07,7.54E-05,6.57E-05, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_T_CELL_MEDIATED_CYTOTOXICITY,18,-0.68,-1.75,0.001789808,0.038561244,0.033563691, postCPET_vs_Baseline,Case,REACTOME_TRNA_PROCESSING_IN_THE_NUCLEUS,35,-0.60,-1.75,0.000757645,0.021562808,0.018786044, postCPET_vs_Baseline,Case,KEGG_ANTIGEN_PROCESSING_AND_PRESENTATION,39,-0.58,-1.75,0.000677732,0.020951271,0.018253257, postCPET_vs_Baseline,Case,REACTOME_TRNA_PROCESSING,50,-0.56,-1.75,0.000424018,0.013822993,0.012042928, postCPET_vs_Baseline,Case,GOBP_POSITIVE_REGULATION_OF_CELL_CELL_ADHESION,139,-0.50,-1.75,8.36E-06,0.000603764,0.000525516, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_T_HELPER_CELL_DIFFERENTIATION,16,-0.70,-1.75,0.002341288,0.046863676,0.040790123, postCPET_vs_Baseline,Case,GOBP_T_CELL_RECEPTOR_SIGNALING_PATHWAY,82,-0.52,-1.75,0.000197511,0.007058525,0.006143737, postCPET_vs_Baseline,Case,GOBP_SOMATIC_DIVERSIFICATION_OF_IMMUNE_RECEPTORS,47,-0.57,-1.74,0.000325055,0.010314289,0.008977553, postCPET_vs_Baseline,Case,GOBP_IMMUNOGLOBULIN_PRODUCTION_INVOLVED_IN_IMMUNOGLOBULIN_MEDIATED_IMMUNE_RESPONSE,40,-0.58,-1.74,0.000839945,0.022177067,0.01930291, postCPET_vs_Baseline,Case,GOBP_T_CELL_MEDIATED_CYTOTOXICITY,23,-0.64,-1.74,0.002061965,0.042684859,0.037152883, postCPET_vs_Baseline,Case,GOBP_AMIDE_BIOSYNTHETIC_PROCESS,461,-0.48,-1.74,1.00E-10,3.22E-08,2.80E-08, postCPET_vs_Baseline,Case,GOBP_POSITIVE_REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING,109,-0.51,-1.74,3.85E-05,0.001933778,0.001683159, postCPET_vs_Baseline,Case,GOBP_IMMUNE_EFFECTOR_PROCESS,278,-0.48,-1.74,9.94E-09,1.76E-06,1.53E-06, postCPET_vs_Baseline,Case,GOBP_TELOMERE_MAINTENANCE,86,-0.52,-1.74,0.000104487,0.004298541,0.003741448, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_NECROTIC_CELL_DEATH,24,-0.63,-1.74,0.002641989,0.051825454,0.045108853, postCPET_vs_Baseline,Case,GOBP_ACTIVATION_OF_IMMUNE_RESPONSE,171,-0.49,-1.73,2.81E-06,0.00023151,0.000201506, postCPET_vs_Baseline,Case,GOBP_ADAPTIVE_IMMUNE_RESPONSE,193,-0.49,-1.73,7.56E-07,7.32E-05,6.37E-05, postCPET_vs_Baseline,Case,REACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA,26,-0.62,-1.73,0.001667727,0.036466264,0.031770298, postCPET_vs_Baseline,Case,GOBP_LEUKOCYTE_MEDIATED_IMMUNITY,185,-0.49,-1.73,1.07E-06,9.45E-05,8.23E-05, postCPET_vs_Baseline,Case,REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA,200,-0.48,-1.73,5.32E-07,5.02E-05,4.37E-05, postCPET_vs_Baseline,Case,GOBP_NEGATIVE_REGULATION_OF_VIRAL_ENTRY_INTO_HOST_CELL,11,-0.76,-1.73,0.002517663,0.049623901,0.043192622, postCPET_vs_Baseline,Case,GOBP_POSITIVE_REGULATION_OF_DNA_RECOMBINATION,44,-0.57,-1.73,0.000844854,0.022223747,0.01934354, postCPET_vs_Baseline,Case,GOBP_INNATE_IMMUNE_RESPONSE,353,-0.48,-1.73,1.39E-10,4.07E-08,3.54E-08, postCPET_vs_Baseline,Case,GOBP_POSITIVE_REGULATION_OF_IMMUNE_RESPONSE,260,-0.48,-1.73,6.30E-08,8.57E-06,7.46E-06, postCPET_vs_Baseline,Case,REACTOME_GENE_SILENCING_BY_RNA,52,-0.55,-1.73,0.000416826,0.013822993,0.012042928, postCPET_vs_Baseline,Case,KEGG_INTESTINAL_IMMUNE_NETWORK_FOR_IGA_PRODUCTION,15,-0.70,-1.73,0.002953587,0.05141535,0.044794305, postCPET_vs_Baseline,Case,GOBP_RESPONSE_TO_VIRUS,202,-0.48,-1.73,4.62E-07,4.87E-05,4.24E-05, postCPET_vs_Baseline,Case,GOBP_RNA_SPLICING,294,-0.48,-1.72,4.23E-09,7.68E-07,6.68E-07, postCPET_vs_Baseline,Case,GOBP_RESPONSE_TO_INTERFERON_GAMMA,68,-0.53,-1.72,0.000534806,0.015259227,0.013281624, postCPET_vs_Baseline,Case,GOBP_NEGATIVE_REGULATION_OF_TUMOR_NECROSIS_FACTOR_SUPERFAMILY_CYTOKINE_PRODUCTION,18,-0.66,-1.72,0.003017873,0.056195972,0.04891295, postCPET_vs_Baseline,Case,REACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS,36,-0.58,-1.72,0.000890577,0.023637519,0.020593582, postCPET_vs_Baseline,Case,GOBP_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_ANTIGEN,35,-0.58,-1.71,0.002120165,0.043359208,0.037739836, postCPET_vs_Baseline,Case,GOBP_TELOMERE_ORGANIZATION,90,-0.51,-1.71,0.000310456,0.009985399,0.008691287, postCPET_vs_Baseline,Case,GOBP_PLATELET_AGGREGATION,54,0.42,1.71,0.001779688,0.038561244,0.033563691, postCPET_vs_Baseline,Case,GOBP_ALPHA_BETA_T_CELL_DIFFERENTIATION,53,-0.55,-1.71,0.000778119,0.020935238,0.018222022, postCPET_vs_Baseline,Case,GOBP_INTERLEUKIN_1_PRODUCTION,41,-0.57,-1.71,0.001150303,0.02816451,0.024514378, postCPET_vs_Baseline,Case,GOBP_T_CELL_DIFFERENTIATION_IN_THYMUS,41,-0.57,-1.71,0.001150303,0.02816451,0.024514378, postCPET_vs_Baseline,Case,REACTOME_NUCLEAR_IMPORT_OF_REV_PROTEIN,24,-0.62,-1.71,0.002473745,0.045611126,0.039737524, postCPET_vs_Baseline,Case,REACTOME_ANTIMICROBIAL_PEPTIDES,11,-0.74,-1.71,0.002468567,0.045611126,0.039737524, postCPET_vs_Baseline,Case,GOBP_CELLULAR_RESPONSE_TO_MECHANICAL_STIMULUS,39,-0.57,-1.71,0.001111771,0.02760313,0.024025752, postCPET_vs_Baseline,Case,GOBP_DEFENSE_RESPONSE_TO_SYMBIONT,143,-0.49,-1.70,3.38E-05,0.001759298,0.001531293, postCPET_vs_Baseline,Case,REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS,26,-0.61,-1.70,0.003070648,0.052939161,0.046121886, postCPET_vs_Baseline,Case,GOBP_ENTRY_INTO_HOST,74,-0.52,-1.70,0.000406741,0.012378025,0.010773828, postCPET_vs_Baseline,Case,REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS,33,-0.59,-1.70,0.001829193,0.038585212,0.033616376, postCPET_vs_Baseline,Case,REACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS,28,-0.60,-1.70,0.001971806,0.040637333,0.035404234, postCPET_vs_Baseline,Case,GOBP_MATURATION_OF_SSU_RRNA,26,-0.61,-1.70,0.002792909,0.053412493,0.046490211, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR,54,-0.54,-1.70,0.00109078,0.027370067,0.023822895, postCPET_vs_Baseline,Case,GOBP_RNA_SPLICING_VIA_TRANSESTERIFICATION_REACTIONS,214,-0.47,-1.70,1.05E-06,9.45E-05,8.23E-05, postCPET_vs_Baseline,Case,GOBP_N_TERMINAL_PROTEIN_AMINO_ACID_ACETYLATION,10,-0.76,-1.70,0.003040632,0.056323327,0.049023799, postCPET_vs_Baseline,Case,GOBP_POSITIVE_REGULATION_OF_RESPONSE_TO_DNA_DAMAGE_STIMULUS,70,-0.52,-1.70,0.000996742,0.02546191,0.022162035, postCPET_vs_Baseline,Case,KEGG_HEMATOPOIETIC_CELL_LINEAGE,34,-0.58,-1.69,0.002508995,0.045611126,0.039737524, postCPET_vs_Baseline,Case,GOBP_LEUKOCYTE_CELL_CELL_ADHESION,183,-0.48,-1.69,4.60E-06,0.000365472,0.000318107, postCPET_vs_Baseline,Case,GOBP_B_CELL_RECEPTOR_SIGNALING_PATHWAY,41,-0.56,-1.69,0.001785693,0.038561244,0.033563691, postCPET_vs_Baseline,Case,KEGG_SPLICEOSOME,107,-0.50,-1.69,0.000102599,0.00459901,0.004006769, postCPET_vs_Baseline,Case,REACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS,53,-0.54,-1.69,0.000878909,0.023637519,0.020593582, postCPET_vs_Baseline,Case,REACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS,33,-0.58,-1.69,0.002458505,0.045611126,0.039737524, postCPET_vs_Baseline,Case,GOBP_PEPTIDE_METABOLIC_PROCESS,482,-0.46,-1.69,1.00E-10,3.22E-08,2.80E-08, postCPET_vs_Baseline,Case,REACTOME_INTERACTIONS_OF_REV_WITH_HOST_CELLULAR_PROTEINS,26,-0.61,-1.69,0.003539441,0.056108583,0.048883164, postCPET_vs_Baseline,Case,GOBP_RNA_PHOSPHODIESTER_BOND_HYDROLYSIS,73,-0.51,-1.68,0.001303202,0.030636059,0.026665613, postCPET_vs_Baseline,Case,GOBP_POSITIVE_REGULATION_OF_TYPE_I_INTERFERON_PRODUCTION,39,-0.56,-1.68,0.001684153,0.037357565,0.032516009, postCPET_vs_Baseline,Case,GOBP_MRNA_PROCESSING,328,-0.46,-1.68,3.65E-09,6.98E-07,6.07E-07, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS,162,-0.48,-1.68,1.47E-05,0.000972438,0.000846409, postCPET_vs_Baseline,Case,GOBP_NEGATIVE_REGULATION_OF_LYMPHOCYTE_ACTIVATION,70,-0.52,-1.68,0.001169466,0.02850876,0.024814013, postCPET_vs_Baseline,Case,GOBP_POSITIVE_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY,64,-0.52,-1.68,0.001912971,0.040476537,0.03523076, postCPET_vs_Baseline,Case,KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY,74,-0.51,-1.68,0.000718766,0.021020465,0.018313541, postCPET_vs_Baseline,Case,REACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS,69,-0.51,-1.68,0.001243953,0.029738763,0.025909134, postCPET_vs_Baseline,Case,GOBP_LEUKOCYTE_PROLIFERATION,154,-0.48,-1.68,2.31E-05,0.0013623,0.001185745, postCPET_vs_Baseline,Case,HALLMARK_KRAS_SIGNALING_UP,70,-0.52,-1.68,0.000900874,0.007953189,0.005525373, postCPET_vs_Baseline,Case,GOBP_RNA_EXPORT_FROM_NUCLEUS,55,-0.53,-1.68,0.001751375,0.038367591,0.033395135, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY,114,-0.49,-1.68,0.000140811,0.005385846,0.004687838, postCPET_vs_Baseline,Case,GOBP_MACROPHAGE_ACTIVATION,38,-0.56,-1.68,0.002747496,0.052829567,0.045982832, postCPET_vs_Baseline,Case,GOBP_POSITIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS,415,-0.46,-1.68,5.82E-10,1.32E-07,1.15E-07, postCPET_vs_Baseline,Case,GOBP_POSITIVE_REGULATION_OF_MYELOID_CELL_DIFFERENTIATION,61,-0.52,-1.67,0.000758841,0.020494498,0.017838402, postCPET_vs_Baseline,Case,REACTOME_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_NLR_SIGNALING_PATHWAYS,45,-0.55,-1.67,0.002282717,0.044977048,0.0391851, postCPET_vs_Baseline,Case,REACTOME_RAC1_GTPASE_CYCLE,109,-0.49,-1.67,7.46E-05,0.003934232,0.003427598, postCPET_vs_Baseline,Case,REACTOME_MRNA_SPLICING,168,-0.47,-1.67,1.28E-05,0.000843875,0.000735204, postCPET_vs_Baseline,Case,GOBP_POSITIVE_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS,118,-0.48,-1.67,0.000107626,0.004351779,0.003787787, postCPET_vs_Baseline,Case,GOBP_NEGATIVE_REGULATION_OF_VIRAL_PROCESS,53,-0.53,-1.67,0.00150009,0.034458906,0.029993017, postCPET_vs_Baseline,Case,REACTOME_SUMOYLATION,123,-0.48,-1.66,0.000173202,0.006901127,0.00601243, postCPET_vs_Baseline,Case,GOBP_NEGATIVE_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS,53,-0.53,-1.66,0.001521367,0.034726432,0.030225872, postCPET_vs_Baseline,Case,GOBP_RNA_CATABOLIC_PROCESS,183,-0.47,-1.66,1.57E-05,0.001012147,0.000880972, postCPET_vs_Baseline,Case,GOBP_MRNA_METABOLIC_PROCESS,471,-0.45,-1.66,1.00E-10,3.22E-08,2.80E-08, postCPET_vs_Baseline,Case,GOBP_NEGATIVE_REGULATION_OF_CELLULAR_MACROMOLECULE_BIOSYNTHETIC_PROCESS,155,-0.47,-1.66,2.62E-05,0.00149543,0.001301621, postCPET_vs_Baseline,Case,GOBP_NUCLEAR_TRANSCRIBED_MRNA_CATABOLIC_PROCESS,88,-0.49,-1.66,0.000820504,0.021787202,0.018963571, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_RESPONSE_TO_DNA_DAMAGE_STIMULUS,136,-0.48,-1.66,0.000109182,0.004364825,0.003799142, postCPET_vs_Baseline,Case,REACTOME_TOLL_LIKE_RECEPTOR_CASCADES,107,-0.49,-1.66,0.000206212,0.007702867,0.006710925, postCPET_vs_Baseline,Case,HALLMARK_MYC_TARGETS_V2,22,-0.62,-1.66,0.00570744,0.031708,0.022028716, postCPET_vs_Baseline,Case,GOBP_POSITIVE_REGULATION_OF_INTERLEUKIN_6_PRODUCTION,41,-0.55,-1.65,0.003060583,0.056544879,0.049216639, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_T_CELL_ACTIVATION,155,-0.47,-1.64,4.81E-05,0.002313692,0.002013836, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_PHAGOCYTOSIS,47,-0.54,-1.64,0.001877384,0.040134053,0.034932662, postCPET_vs_Baseline,Case,GOBP_POSITIVE_REGULATION_OF_DNA_REPAIR,53,-0.53,-1.64,0.002074584,0.042798119,0.037251464, postCPET_vs_Baseline,Case,REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM,62,-0.51,-1.64,0.001353079,0.031512878,0.027454787, postCPET_vs_Baseline,Case,GOBP_VIRAL_GENOME_REPLICATION,90,-0.49,-1.64,0.001135623,0.028093539,0.024452605, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_CELL_ACTIVATION,297,-0.45,-1.64,2.79E-07,3.23E-05,2.82E-05, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_VIRAL_GENOME_REPLICATION,57,-0.52,-1.64,0.00166657,0.037083795,0.032277719, postCPET_vs_Baseline,Case,GOBP_DOUBLE_STRAND_BREAK_REPAIR_VIA_NONHOMOLOGOUS_END_JOINING,45,-0.54,-1.64,0.00264851,0.051825454,0.045108853, postCPET_vs_Baseline,Case,GOBP_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE,103,-0.48,-1.64,0.000417091,0.012505668,0.010884928, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_DNA_REPAIR,86,-0.49,-1.63,0.000977325,0.025147469,0.021888346, postCPET_vs_Baseline,Case,GOBP_MYELOID_LEUKOCYTE_DIFFERENTIATION,107,-0.48,-1.63,0.000473452,0.01390101,0.012099433, postCPET_vs_Baseline,Case,GOBP_DNA_INTEGRITY_CHECKPOINT_SIGNALING,63,-0.51,-1.63,0.002992113,0.056097194,0.048826974, postCPET_vs_Baseline,Case,REACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE,54,-0.52,-1.63,0.002603056,0.046672795,0.040662476, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS,180,-0.46,-1.62,3.05E-05,0.001656709,0.001441999, postCPET_vs_Baseline,Case,GOBP_NEGATIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS,180,-0.46,-1.62,3.17E-05,0.001684203,0.00146593, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_CELL_CELL_ADHESION,205,-0.45,-1.62,2.67E-05,0.001513495,0.001317346, postCPET_vs_Baseline,Case,GOBP_IMMUNE_SYSTEM_DEVELOPMENT,464,-0.44,-1.62,3.02E-09,5.94E-07,5.17E-07, postCPET_vs_Baseline,Case,KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION,68,-0.49,-1.62,0.003272593,0.055356216,0.048227683, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_RNA_SPLICING,111,-0.47,-1.62,0.000695275,0.019217834,0.016727195, postCPET_vs_Baseline,Case,GOBP_VIRAL_LIFE_CYCLE,188,-0.45,-1.62,3.15E-05,0.001684203,0.00146593, postCPET_vs_Baseline,Case,GOBP_POSITIVE_REGULATION_OF_CYTOKINE_PRODUCTION,208,-0.45,-1.61,2.62E-05,0.00149543,0.001301621, postCPET_vs_Baseline,Case,GOBP_NUCLEIC_ACID_PHOSPHODIESTER_BOND_HYDROLYSIS,118,-0.47,-1.61,0.000392003,0.012165839,0.010589141, postCPET_vs_Baseline,Case,HALLMARK_IL2_STAT5_SIGNALING,96,-0.48,-1.61,0.00111827,0.007987645,0.005549311, postCPET_vs_Baseline,Case,GOBP_MRNA_CATABOLIC_PROCESS,156,-0.46,-1.61,0.000278655,0.009170989,0.007982425, postCPET_vs_Baseline,Case,REACTOME_CLEC7A_DECTIN_1_SIGNALING,87,-0.48,-1.61,0.00156716,0.035123966,0.030600854, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_LEUKOCYTE_PROLIFERATION,118,-0.46,-1.61,0.000472778,0.01390101,0.012099433, postCPET_vs_Baseline,Case,GOBP_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY,89,-0.48,-1.60,0.001258165,0.030027442,0.026135873, postCPET_vs_Baseline,Case,REACTOME_NEUTROPHIL_DEGRANULATION,300,-0.44,-1.60,1.53E-06,0.000125074,0.000108967, postCPET_vs_Baseline,Case,GOBP_CELLULAR_NITROGEN_COMPOUND_CATABOLIC_PROCESS,251,-0.44,-1.60,3.88E-06,0.000315515,0.000274624, postCPET_vs_Baseline,Case,GOBP_TUMOR_NECROSIS_FACTOR_SUPERFAMILY_CYTOKINE_PRODUCTION,72,-0.49,-1.60,0.00266866,0.051877585,0.045154228, postCPET_vs_Baseline,Case,GOBP_DNA_RECOMBINATION,146,-0.45,-1.59,0.000170564,0.006385755,0.005558158, postCPET_vs_Baseline,Case,REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM,398,-0.44,-1.59,6.87E-08,7.70E-06,6.71E-06, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_DOUBLE_STRAND_BREAK_REPAIR,66,-0.49,-1.59,0.002996713,0.056097194,0.048826974, postCPET_vs_Baseline,Case,REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES,194,-0.44,-1.59,0.000139116,0.00580082,0.005053815, postCPET_vs_Baseline,Case,REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION,82,-0.47,-1.58,0.002443446,0.045611126,0.039737524, postCPET_vs_Baseline,Case,GOBP_VIRAL_PROCESS,263,-0.44,-1.58,1.82E-05,0.001132241,0.000985502, postCPET_vs_Baseline,Case,GOBP_DOUBLE_STRAND_BREAK_REPAIR,145,-0.45,-1.58,0.000376615,0.011843975,0.01030899, postCPET_vs_Baseline,Case,GOBP_TRANSLATIONAL_INITIATION,93,-0.47,-1.58,0.002044297,0.04267094,0.037140768, postCPET_vs_Baseline,Case,REACTOME_RAC3_GTPASE_CYCLE,64,-0.49,-1.58,0.002825074,0.050152049,0.043693687, postCPET_vs_Baseline,Case,REACTOME_C_TYPE_LECTIN_RECEPTORS_CLRS,102,-0.46,-1.58,0.000864999,0.023637519,0.020593582, postCPET_vs_Baseline,Case,GOBP_NEGATIVE_REGULATION_OF_CELLULAR_AMIDE_METABOLIC_PROCESS,131,-0.45,-1.58,0.000787877,0.02111749,0.018380654, postCPET_vs_Baseline,Case,GOBP_ORGANIC_CYCLIC_COMPOUND_CATABOLIC_PROCESS,263,-0.44,-1.57,2.35E-05,0.001375961,0.001197636, postCPET_vs_Baseline,Case,HALLMARK_TNFA_SIGNALING_VIA_NFKB,89,-0.48,-1.57,0.000954383,0.007953189,0.005525373, postCPET_vs_Baseline,Case,GOBP_POSITIVE_REGULATION_OF_CELL_ADHESION,210,-0.44,-1.57,0.000184917,0.006738893,0.00586553, postCPET_vs_Baseline,Case,GOBP_POSITIVE_REGULATION_OF_DNA_METABOLIC_PROCESS,134,-0.45,-1.57,0.001001454,0.025490251,0.022186704, postCPET_vs_Baseline,Case,GOBP_HISTONE_METHYLATION,93,-0.46,-1.56,0.00295726,0.055653123,0.048440455, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_INNATE_IMMUNE_RESPONSE,125,-0.45,-1.56,0.001710766,0.037711465,0.032824043, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_DEFENSE_RESPONSE,274,-0.43,-1.56,1.84E-05,0.001132241,0.000985502, postCPET_vs_Baseline,Case,REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS,110,-0.45,-1.56,0.001741477,0.037620093,0.032775541, postCPET_vs_Baseline,Case,GOBP_RNA_LOCALIZATION,137,-0.45,-1.56,0.000715069,0.01968804,0.017136462, postCPET_vs_Baseline,Case,REACTOME_SIGNALING_BY_NOTCH4,64,-0.48,-1.55,0.003567417,0.056108583,0.048883164, postCPET_vs_Baseline,Case,REACTOME_INTERLEUKIN_1_FAMILY_SIGNALING,101,-0.46,-1.55,0.001799393,0.038408471,0.033462395, postCPET_vs_Baseline,Case,GOBP_CYTOKINE_PRODUCTION,330,-0.43,-1.55,3.93E-06,0.000315637,0.00027473, postCPET_vs_Baseline,Case,GOBP_INFLAMMATORY_RESPONSE,293,-0.43,-1.54,1.70E-05,0.001080185,0.000940193, postCPET_vs_Baseline,Case,HALLMARK_IL6_JAK_STAT3_SIGNALING,37,-0.52,-1.54,0.013221547,0.045311731,0.031479729, postCPET_vs_Baseline,Case,GOBP_NEGATIVE_REGULATION_OF_CELLULAR_CATABOLIC_PROCESS,160,-0.44,-1.54,0.000718601,0.019708603,0.01715436, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_MYELOID_CELL_DIFFERENTIATION,109,-0.45,-1.53,0.002695236,0.052107903,0.045354696, postCPET_vs_Baseline,Case,GOBP_POSITIVE_REGULATION_OF_CELL_DEATH,296,-0.42,-1.53,3.92E-05,0.001939888,0.001688478, postCPET_vs_Baseline,Case,REACTOME_CELLULAR_RESPONSES_TO_STIMULI,500,-0.42,-1.53,9.40E-08,9.91E-06,8.63E-06, postCPET_vs_Baseline,Case,GOBP_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING,155,-0.43,-1.52,0.001463178,0.033834802,0.029449798, postCPET_vs_Baseline,Case,GOBP_RESPONSE_TO_CYTOKINE,413,-0.42,-1.52,1.60E-06,0.000138347,0.000120418, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_INFLAMMATORY_RESPONSE,140,-0.43,-1.52,0.001488157,0.034300316,0.029854981, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY,198,-0.42,-1.51,0.000514488,0.014738947,0.012828773, postCPET_vs_Baseline,Case,GOBP_DNA_REPAIR,279,-0.42,-1.51,7.43E-05,0.003333584,0.00290155, postCPET_vs_Baseline,Case,HALLMARK_HYPOXIA,93,-0.46,-1.51,0.003838763,0.023992266,0.016668311, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_CELLULAR_AMIDE_METABOLIC_PROCESS,282,-0.42,-1.51,0.00011963,0.00472907,0.00411618, postCPET_vs_Baseline,Case,GOBP_BIOLOGICAL_PROCESS_INVOLVED_IN_SYMBIOTIC_INTERACTION,147,-0.43,-1.50,0.001916286,0.040476537,0.03523076, postCPET_vs_Baseline,Case,GOBP_POSTTRANSCRIPTIONAL_REGULATION_OF_GENE_EXPRESSION,329,-0.41,-1.50,1.53E-05,0.000997842,0.000868521, postCPET_vs_Baseline,Case,REACTOME_SIGNALING_BY_INTERLEUKINS,254,-0.42,-1.50,0.000131419,0.005610343,0.004887868, postCPET_vs_Baseline,Case,GOBP_CYTOKINE_MEDIATED_SIGNALING_PATHWAY,197,-0.42,-1.50,0.001107463,0.027592987,0.024016924, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_DNA_METABOLIC_PROCESS,226,-0.42,-1.49,0.00042663,0.012684172,0.011040298, postCPET_vs_Baseline,Case,GOBP_CELLULAR_RESPONSE_TO_EXTERNAL_STIMULUS,169,-0.42,-1.49,0.00265614,0.051825454,0.045108853, postCPET_vs_Baseline,Case,GOBP_HISTONE_MODIFICATION,300,-0.41,-1.48,0.00018571,0.006738893,0.00586553, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_CELL_ADHESION,339,-0.41,-1.48,5.73E-05,0.002682965,0.002335252, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_MRNA_METABOLIC_PROCESS,197,-0.41,-1.48,0.001665837,0.037083795,0.032277719, postCPET_vs_Baseline,Case,GOBP_HOMEOSTASIS_OF_NUMBER_OF_CELLS,162,-0.42,-1.47,0.002515676,0.049623901,0.043192622, postCPET_vs_Baseline,Case,HALLMARK_INFLAMMATORY_RESPONSE,77,-0.45,-1.46,0.011289618,0.045311731,0.031479729, postCPET_vs_Baseline,Case,HALLMARK_UNFOLDED_PROTEIN_RESPONSE,77,-0.45,-1.45,0.013076435,0.045311731,0.031479729, postCPET_vs_Baseline,Case,GOBP_NEGATIVE_REGULATION_OF_CATABOLIC_PROCESS,190,-0.41,-1.45,0.002763542,0.052994109,0.046126049, postCPET_vs_Baseline,Case,HALLMARK_E2F_TARGETS,115,-0.42,-1.43,0.013593519,0.045311731,0.031479729, postCPET_vs_Baseline,Case,HALLMARK_APOPTOSIS,105,-0.43,-1.43,0.010469357,0.045311731,0.031479729, postCPET_vs_Baseline,Case,GOBP_NUCLEAR_TRANSPORT,200,-0.40,-1.42,0.002827258,0.053917277,0.046929575, postCPET_vs_Baseline,Case,GOBP_PEPTIDYL_LYSINE_MODIFICATION,231,-0.39,-1.42,0.002717667,0.05239839,0.045607536, postCPET_vs_Baseline,Case,GOBP_NEGATIVE_REGULATION_OF_TRANSCRIPTION_BY_RNA_POLYMERASE_II,417,-0.39,-1.42,0.000146532,0.005574525,0.004852064, postCPET_vs_Baseline,Case,REACTOME_NERVOUS_SYSTEM_DEVELOPMENT,329,-0.39,-1.41,0.000344393,0.011650867,0.010150519, postCPET_vs_Baseline,Case,GOBP_CELL_CELL_ADHESION,350,-0.39,-1.41,0.000414472,0.012480015,0.0108626, postCPET_vs_Baseline,Case,HALLMARK_COMPLEMENT,121,-0.41,-1.41,0.013494296,0.045311731,0.031479729, postCPET_vs_Baseline,Case,GOBP_DNA_METABOLIC_PROCESS,459,-0.38,-1.41,0.000123567,0.00485756,0.004228018, postCPET_vs_Baseline,Case,GOBP_CELLULAR_RESPONSE_TO_DNA_DAMAGE_STIMULUS,438,-0.38,-1.38,0.000317024,0.010150509,0.008834998, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_CELLULAR_RESPONSE_TO_STRESS,361,-0.38,-1.37,0.001230294,0.029610739,0.025773174, postCPET_vs_Baseline,Case,REACTOME_DEVELOPMENTAL_BIOLOGY,465,-0.38,-1.37,0.000275971,0.009896333,0.008621926, postCPET_vs_Baseline,Case,GOBP_NEGATIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS,284,-0.38,-1.36,0.002395966,0.047757332,0.041567961, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_CELLULAR_MACROMOLECULE_BIOSYNTHETIC_PROCESS,407,-0.37,-1.35,0.001355712,0.031587608,0.02749384, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS,400,-0.37,-1.34,0.001504777,0.034458906,0.029993017, postCPET_vs_Baseline,Case,REACTOME_ADAPTIVE_IMMUNE_SYSTEM,462,-0.37,-1.33,0.00071969,0.021020465,0.018313541, postCPET_vs_Baseline,Case,GOBP_REGULATION_OF_MULTICELLULAR_ORGANISMAL_DEVELOPMENT,487,-0.36,-1.31,0.001262225,0.030027442,0.026135873, postCPET_vs_Baseline,Control,No significant results,--,--,--,--,--,--,