"","Term","Overlap","P.value","Adjusted.P.value","Old.P.value","Old.Adjusted.P.value","Odds.Ratio","Combined.Score","Genes" "1","Circadian entrainment","11/97",3.26622567504556e-07,7.3490077688525e-05,0,0,8.35786821705426,124.820253257436,"CAMK2B;GRIA2;CAMK2D;GNB4;ITPR3;GNG12;GRIN2C;GNG11;CACNA1H;PRKG1;KCNJ3" "2","Axon guidance","13/182",5.74778277601669e-06,0.000646625562301877,0,0,5.03871966959215,60.80070040542,"EPHA5;CAMK2B;EPHA7;CAMK2D;EPHA8;PTCH1;SEMA3A;SEMA4F;NRAS;BOC;SLIT2;BMPR1B;EPHA2" "3","Cholinergic synapse","10/113",1.08071467312246e-05,0.000810536004841847,0,0,6.31745314969519,72.2419903758285,"CAMK2B;CAMK2D;NRAS;KCNJ12;KCNQ2;GNB4;ITPR3;GNG12;GNG11;KCNJ3" "4","Dopaminergic synapse","10/132",4.19081203786835e-05,0.00235733177130094,0,0,5.3284134851043,53.7105728230763,"CAMK2B;GRIA2;CAMK2D;GNB4;ITPR3;GNG12;CLOCK;GNG11;SCN1A;KCNJ3" "5","Proteoglycans in cancer","12/205",9.26923595545459e-05,0.00417115617995456,0,0,4.05413554681408,37.647612881653,"CAMK2B;NRAS;CAMK2D;CCND1;PLAU;WNT7B;CAV1;PTCH1;MMP2;KDR;GAB1;ITPR3" "6","AGE-RAGE signaling pathway in diabetic complications","8/100",0.000168361020675393,0.00631353827532722,0,0,5.62404936145789,48.8696142493747,"EGR1;JUN;NRAS;CXCL8;CCND1;MMP2;CCL2;ICAM1" "7","Long-term potentiation","6/67",0.000606267114640608,0.0170729556553567,0,0,6.32991131416286,46.8931849754405,"CAMK2B;GRIA2;CAMK2D;NRAS;ITPR3;GRIN2C" "8","GnRH signaling pathway","7/93",0.000621238716808818,0.0170729556553567,0,0,5.24866126070991,38.7550395230152,"CAMK2B;EGR1;CAMK2D;NRAS;JUN;MMP2;ITPR3" "9","Amphetamine addiction","6/69",0.000709641875506544,0.0170729556553567,0,0,6.12833723653396,44.4350419279304,"CAMK2B;GRIA2;ARC;CAMK2D;JUN;GRIN2C" "10","Biosynthesis of unsaturated fatty acids","4/27",0.000758798029126966,0.0170729556553567,0,0,11.1406316385781,80.0317901276714,"FADS2;SCD;SCD5;ELOVL6" "11","Kaposi sarcoma-associated herpesvirus infection","10/193",0.000913873855295307,0.0186928743128585,0,0,3.54120145961549,24.7806833509055,"JUN;NRAS;CXCL8;CCND1;GNB4;ITPR3;GNG12;GNG11;CXCL2;ICAM1" "12","Apelin signaling pathway","8/137",0.00138047352071297,0.0258838785133682,0,0,4.00337708189424,26.3635540252167,"EGR1;NRAS;CCND1;GNB4;ITPR3;GNG12;PPARGC1A;GNG11" "13","Fluid shear stress and atherosclerosis","8/139",0.001514134998282,0.026206182662573,0,0,3.94185372735747,25.5941052742369,"CDH5;JUN;CAV1;MMP2;KDR;CCL2;BMPR1B;ICAM1" "14","Serotonergic synapse","7/113",0.00194729670421794,0.029609317496227,0,0,4.25400322740814,26.5505663843816,"NRAS;KCND2;GNB4;ITPR3;GNG12;GNG11;KCNJ3" "15","Glutamatergic synapse","7/114",0.00204767503064046,0.029609317496227,0,0,4.21403098868667,26.0892776516982,"GRIA2;GNB4;ITPR3;GNG12;GRIN2C;GNG11;KCNJ3" "16","ErbB signaling pathway","6/85",0.00210555146639837,0.029609317496227,0,0,4.88317078231998,30.0958500857493,"CAMK2B;CAMK2D;NRAS;JUN;SHC3;GAB1" "17","Long-term depression","5/60",0.00239018333353493,0.0316347794144328,0,0,5.83303624480095,35.2104537022783,"GRIA2;GRID2;NRAS;ITPR3;PRKG1" "18","Neurotrophin signaling pathway","7/119",0.00261100460872073,0.0326375576090092,0,0,4.02487664473684,23.9400476826022,"CAMK2B;JUN;CAMK2D;NRAS;SHC3;GAB1;NGF" "19","Oxytocin signaling pathway","8/154",0.00287481693646083,0.0340438847738783,0,0,3.53415615534156,20.6810558217387,"CAMK2B;JUN;CAMK2D;NRAS;CCND1;KCNJ12;ITPR3;KCNJ3" "20","Ras signaling pathway","10/232",0.00354015062721899,0.0395610338428527,0,0,2.91326209930861,16.4412452057957,"NRAS;SHC3;KDR;GAB1;GNB4;GNG12;RAPGEF5;NGF;GNG11;EPHA2" "21","Bladder cancer","4/41",0.00369236315866625,0.0395610338428527,0,0,6.9203274936174,38.7641355880536,"NRAS;CXCL8;CCND1;MMP2" "22","Hippo signaling pathway","8/163",0.00406179113039335,0.0398617210275374,0,0,3.32741403172575,18.3211783402865,"MOB1B;SMAD1;CCND2;FRMD6;CCND1;WNT7B;BMPR1B;BMP5" "23","Relaxin signaling pathway","7/129",0.00408779877422071,0.0398617210275374,0,0,3.69308132010354,20.311019007606,"JUN;NRAS;SHC3;MMP2;GNB4;GNG12;GNG11" "24","Focal adhesion","9/201",0.00433510885766275,0.0398617210275374,0,0,3.02623137417219,16.4657508045238,"LAMA5;JUN;RELN;CCND2;SHC3;CCND1;CAV1;KDR;COL9A1" "25","Calcium signaling pathway","10/240",0.00449136992240274,0.0398617210275374,0,0,2.81077567528528,15.1939220155254,"CAMK2B;CAMK2D;PLN;KDR;CASQ2;ITPR3;ATP2B1;GRIN2C;NGF;CACNA1H" "26","Terpenoid backbone biosynthesis","3/22",0.00460624331873765,0.0398617210275374,0,0,10.0837320574163,54.2539336849514,"IDI1;HMGCS1;HMGCR" "27","Glycosphingolipid biosynthesis","4/45",0.00517543728303242,0.0431286440252702,0,0,6.24390243902439,32.8668499934524,"FUT9;B3GALT2;B3GALT1;ST6GALNAC3" "28","PPAR signaling pathway","5/74",0.00591394449851225,0.0475227682916163,0,0,4.6462063086104,23.8370931124087,"FADS2;HMGCS1;SCD;SCD5;CD36" "29","Glioma","5/75",0.00625758690439975,0.0485502432237912,0,0,4.57959850606909,23.2367025975561,"CAMK2B;CAMK2D;NRAS;SHC3;CCND1" "30","Lipid and atherosclerosis","9/215",0.00667317316716967,0.0498717652648778,0,0,2.81853983154375,14.1199256746199,"CAMK2B;JUN;NRAS;CAMK2D;CXCL8;CCL2;CD36;CXCL2;ICAM1" "31","cAMP signaling pathway","9/216",0.00687122099204983,0.0498717652648778,0,0,2.80477972934063,13.9689627175752,"CAMK2B;GRIA2;JUN;CAMK2D;PLN;PTCH1;SOX9;ATP2B1;GRIN2C" "32","Malaria","4/50",0.00753050738799916,0.0529488800718691,0,0,5.5638011613086,27.2002713764869,"CXCL8;CCL2;CD36;ICAM1" "33","PI3K-Akt signaling pathway","12/354",0.00978474336851902,0.0667141593308115,0,0,2.27037493399049,10.5048679491696,"LAMA5;NRAS;RELN;CCND2;CCND1;KDR;COL9A1;GNB4;GNG12;NGF;GNG11;EPHA2" "34","Chemokine signaling pathway","8/192",0.0105490361755269,0.0698097982203987,0,0,2.79882336059693,12.7394624527868,"NRAS;SHC3;CXCL8;GNB4;CCL2;GNG12;GNG11;CXCL2" "35","Hedgehog signaling pathway","4/56",0.0111722977708503,0.0701791940906953,0,0,4.92032072162365,22.1134858764143,"CCND2;CCND1;PTCH1;BOC" "36","AMPK signaling pathway","6/120",0.0112286710545112,0.0701791940906953,0,0,3.3779119930975,15.1644091558595,"CCND1;SCD;SCD5;CD36;HMGCR;PPARGC1A" "37","ECM-receptor interaction","5/88",0.0120773079015276,0.0734430885903703,0,0,3.85975273643594,17.0463160717087,"LAMA5;RELN;COL9A1;CD36;NPNT" "38","Rheumatoid arthritis","5/93",0.0150568120578286,0.0883494550649151,0,0,3.6395202020202,15.2711529366022,"JUN;CXCL8;CCL2;CXCL2;ICAM1" "39","Wnt signaling pathway","7/166",0.0153314001077275,0.0883494550649151,0,0,2.82832671300894,11.8163311472496,"CAMK2B;JUN;CAMK2D;CCND2;CCND1;WNT7B;LGR5" "40","TGF-beta signaling pathway","5/94",0.0157065697893182,0.0883494550649151,0,0,3.59844312256738,14.9467675417267,"SMAD1;PITX2;BMPR1B;BMP5;FBN1" "41","GnRH secretion","4/64",0.0175577829375359,0.0963536868523314,0,0,4.26254071661238,17.2302891208803,"NRAS;ITPR3;CACNA1H;KCNJ3" "42","Aldosterone synthesis and secretion","5/98",0.0184920537715683,0.0990645737762587,0,0,3.44296858528358,13.7388706124747,"CAMK2B;CAMK2D;ITPR3;ATP2B1;CACNA1H" "43","Pathways in cancer","15/531",0.0196294877414331,0.102712435856336,0,0,1.882954902577,7.40137295110902,"CAMK2B;LAMA5;JUN;CAMK2D;CXCL8;WNT7B;PTCH1;MMP2;GNG12;GNG11;DLL3;NRAS;CCND2;CCND1;GNB4" "44","Estrogen signaling pathway","6/137",0.0203558661906198,0.103911528285466,0,0,2.93700412964585,11.4378281865957,"JUN;NRAS;SHC3;MMP2;ITPR3;KCNJ3" "45","Melanogenesis","5/101",0.0207823056570931,0.103911528285466,0,0,3.33486519607843,12.9181117181762,"CAMK2B;CAMK2D;NRAS;WNT7B;TYRP1" "46","C-type lectin receptor signaling pathway","5/104",0.023250274559669,0.110549638931296,0,0,3.23331352743117,12.1619094608552,"EGR2;JUN;NRAS;EGR3;ITPR3" "47","NOD-like receptor signaling pathway","7/181",0.0234000766018663,0.110549638931296,0,0,2.58252041742287,9.6974054439495,"JUN;CXCL8;TRIP6;CCL2;ITPR3;ANTXR2;CXCL2" "48","Prolactin signaling pathway","4/70",0.0235839229720097,0.110549638931296,0,0,3.87385253183299,14.5160615814603,"NRAS;CCND2;SHC3;CCND1" "49","Human cytomegalovirus infection","8/225",0.0249008790765663,0.114340771269947,0,0,2.36918069687153,8.7490340819587,"NRAS;CXCL8;CCND1;GNB4;CCL2;ITPR3;GNG12;GNG11" "50","Breast cancer","6/147",0.0275850521776831,0.124132734799574,0,0,2.72731077781653,9.79235818540673,"JUN;NRAS;SHC3;CCND1;WNT7B;DLL3" "51","Retrograde endocannabinoid signaling","6/148",0.0283900764600937,0.125250337323943,0,0,2.70796582775341,9.64500417439659,"GRIA2;GNB4;ITPR3;GNG12;GNG11;KCNJ3" "52","Gastric cancer","6/149",0.0292104479086086,0.126391361143018,0,0,2.68889143643242,9.50046874022048,"NRAS;SHC3;CCND1;WNT7B;GAB1;CDH17" "53","Gastric acid secretion","4/76",0.0307244729739721,0.13043408338007,0,0,3.5499457111835,12.3633809357838,"CAMK2B;CAMK2D;SLC26A7;ITPR3" "54","Cushing syndrome","6/155",0.0344601320482909,0.143583883534546,0,0,2.57982176257014,8.68871642203041,"CAMK2B;CAMK2D;CCND1;WNT7B;ITPR3;CACNA1H" "55","Cellular senescence","6/156",0.0353904557961509,0.14477913734789,0,0,2.56249180327869,8.5620874449597,"NRAS;CCND2;CXCL8;CCND1;ITPR3;HIPK1" "56","Steroid biosynthesis","2/20",0.0380868642114108,0.153027579420847,0,0,7.07335490830636,23.1149162587988,"CYP2R1;MSMO1" "57","Cocaine addiction","3/49",0.0405852391391867,0.159603767447832,0,0,4.15930265386787,13.3278649796949,"GRIA2;JUN;GRIN2C" "58","MAPK signaling pathway","9/294",0.0411423044976634,0.159603767447832,0,0,2.0289996514465,6.47396648157415,"JUN;DUSP2;NRAS;KDR;GNG12;NGF;DUSP6;CACNA1H;EPHA2" "59","Cytokine-cytokine receptor interaction","9/295",0.0418848769453245,0.159730462927085,0,0,2.02180104663548,6.41483192318804,"GDF11;CXCL8;MSTN;TNFRSF19;CCL2;BMPR1B;NGF;CXCL2;BMP5" "60","Morphine addiction","4/91",0.0535968949031194,0.200988355886698,0,0,2.93563967202067,8.59045711045665,"GNB4;GNG12;GNG11;KCNJ3" "61","Human T-cell leukemia virus 1 infection","7/219",0.0557657136698173,0.205693206159162,0,0,2.11548845580933,6.10656061783934,"EGR1;EGR2;JUN;NRAS;CCND2;CCND1;ICAM1" "62","Legionellosis","3/57",0.0589497531259987,0.210833141810914,0,0,3.54166666666667,10.0267056828434,"CXCL8;EEF1A2;CXCL2" "63","IL-17 signaling pathway","4/94",0.0590332797070559,0.210833141810914,0,0,2.83735070575461,8.02872057892629,"JUN;CXCL8;CCL2;CXCL2" "64","Mineral absorption","3/60",0.0666833853965112,0.227457312418944,0,0,3.35475051264525,9.08399159837827,"ATP2B1;STEAP2;TRPM6" "65","Viral myocarditis","3/60",0.0666833853965112,0.227457312418944,0,0,3.35475051264525,9.08399159837827,"CCND1;CAV1;ICAM1" "66","Inflammatory mediator regulation of TRP channels","4/98",0.0667208116428902,0.227457312418944,0,0,2.7160579388731,7.35301622949146,"CAMK2B;CAMK2D;ITPR3;NGF" "67","Alcoholism","6/186",0.0709863413176328,0.235418874480128,0,0,2.13213114754098,5.64005786198325,"NRAS;SHC3;GNB4;GNG12;GRIN2C;GNG11" "68","Apoptosis","5/142",0.0711488153984388,0.235418874480128,0,0,2.33194981155479,6.16330045324884,"JUN;NRAS;ITPR3;CTSF;NGF" "69","NF-kappa B signaling pathway","4/104",0.0791734554197739,0.256897387476336,0,0,2.55231270358306,6.47295647809849,"CXCL8;PLAU;CXCL2;ICAM1" "70","Transcriptional misregulation in cancer","6/192",0.0799236316593045,0.256897387476336,0,0,2.06271813855103,5.21183630763649,"SMAD1;CCND2;CXCL8;PLAU;ETV1;DUSP6" "71","Adrenergic signaling in cardiomyocytes","5/150",0.0852728491043244,0.266298029063646,0,0,2.20238900157764,5.42205966391321,"CAMK2B;CAMK2D;PLN;AGTR2;ATP2B1" "72","Glucagon signaling pathway","4/107",0.0858035418263366,0.266298029063646,0,0,2.47759400398469,6.08421519104748,"CAMK2B;CAMK2D;ITPR3;PPARGC1A" "73","Acute myeloid leukemia","3/67",0.086398916096205,0.266298029063646,0,0,2.98675933441558,7.31391696626573,"NRAS;CCND1;DUSP6" "74","Renal cell carcinoma","3/69",0.0924370091079112,0.281058473638919,0,0,2.89595631641086,6.89593183028403,"NRAS;JUN;GAB1" "75","Epithelial cell signaling in Helicobacter pylori infection","3/70",0.0955199853990681,0.28230706417536,0,0,2.85258771079667,6.69907341048177,"JUN;CXCL8;CXCL2" "76","TNF signaling pathway","4/112",0.0974311634613076,0.28230706417536,0,0,2.36228736880203,5.50084401996955,"JUN;CCL2;CXCL2;ICAM1" "77","Diabetic cardiomyopathy","6/203",0.0978664489141249,0.28230706417536,0,0,1.94644253973537,4.52382734041768,"CAMK2B;CAMK2D;PLN;MMP2;PDK4;CD36" "78","Viral carcinogenesis","6/203",0.0978664489141249,0.28230706417536,0,0,1.94644253973537,4.52382734041768,"EGR2;JUN;NRAS;EGR3;CCND2;CCND1" "79","p53 signaling pathway","3/73",0.105015681103655,0.299095294282562,0,0,2.72991651205937,6.15226432520779,"CCND2;CCND1;PERP" "80","Hepatitis B","5/162",0.108992529997779,0.306415122903814,0,0,2.03280462928271,4.5056625337019,"EGR2;JUN;NRAS;EGR3;CXCL8" "81","Rap1 signaling pathway","6/210",0.110309444245373,0.306415122903814,0,0,1.87897782063645,4.14214221890435,"NRAS;P2RY1;KDR;RAPGEF5;NGF;EPHA2" "82","Thyroid cancer","2/37",0.112628179624813,0.307675579015528,0,0,3.63458159963014,7.93670256441816,"NRAS;CCND1" "83","Human immunodeficiency virus 1 infection","6/212",0.11400703552643,0.307675579015528,0,0,1.86054432595894,4.04016291942903,"JUN;NRAS;GNB4;ITPR3;GNG12;GNG11" "84","Chronic myeloid leukemia","3/76",0.11486554949913,0.307675579015528,0,0,2.61732787760185,5.66387912569345,"NRAS;SHC3;CCND1" "85","Bacterial invasion of epithelial cells","3/77",0.118223944569404,0.312945735624893,0,0,2.58182695682696,5.51265138576028,"SHC3;CAV1;GAB1" "86","cGMP-PKG signaling pathway","5/167",0.119731913283273,0.313252098706238,0,0,1.96955942870976,4.18039006745188,"PLN;ITPR3;PDE5A;ATP2B1;PRKG1" "87","Hepatocellular carcinoma","5/168",0.121937693134292,0.315356102933515,0,0,1.95737599743374,4.11879880589117,"NRAS;SHC3;CCND1;WNT7B;GAB1" "88","Nicotine addiction","2/40",0.128061143411238,0.32742905985828,0,0,3.34712996082439,6.87918030413866,"GRIA2;GRIN2C" "89","Fat digestion and absorption","2/43",0.143951392290478,0.359010206720755,0,0,3.10174441550241,6.01204789374304,"MTTP;CD36" "90","Synthesis and degradation of ketone bodies","1/10",0.145088063484166,0.359010206720755,0,0,7.05376344086022,13.6166864254927,"HMGCS1" "91","FoxO signaling pathway","4/131",0.147634326128876,0.359010206720755,0,0,2.00692503013671,3.83928136322432,"NRAS;CCND2;CCND1;PLK2" "92","Natural killer cell mediated cytotoxicity","4/131",0.147634326128876,0.359010206720755,0,0,2.00692503013671,3.83928136322432,"NRAS;SHC3;SH3BP2;ICAM1" "93","Colorectal cancer","3/86",0.149986486363338,0.359010206720755,0,0,2.30081364418714,4.36512683762066,"NRAS;JUN;CCND1" "94","Insulin secretion","3/86",0.149986486363338,0.359010206720755,0,0,2.30081364418714,4.36512683762066,"CAMK2B;CAMK2D;ITPR3" "95","Gap junction","3/88",0.157385830676366,0.372755914759815,0,0,2.24644766997708,4.1538052248979,"NRAS;ITPR3;PRKG1" "96","GABAergic synapse","3/89",0.16112727540096,0.377642051721,0,0,2.22021292660828,4.05313345525978,"GNB4;GNG12;GNG11" "97","Valine, leucine and isoleucine degradation","2/48",0.171252422344869,0.39723500028449,0,0,2.7638947516533,4.87721471657622,"HMGCS1;BCAT1" "98","Salivary secretion","3/93",0.176353308237099,0.404855016985174,0,0,2.1211038961039,3.68067918274328,"ITPR3;ATP2B1;PRKG1" "99","Cholesterol metabolism","2/50",0.1824009659887,0.404855016985174,0,0,2.64846278317152,4.50648630114333,"CETP;CD36" "100","N-Glycan biosynthesis","2/50",0.1824009659887,0.404855016985174,0,0,2.64846278317152,4.50648630114333,"MGAT4C;SRD5A3" "101","Signaling pathways regulating pluripotency of stem cells","4/143",0.183534274366612,0.404855016985174,0,0,1.83254048227216,3.1068045575753,"SMAD1;NRAS;WNT7B;BMPR1B" "102","Spinocerebellar ataxia","4/143",0.183534274366612,0.404855016985174,0,0,1.83254048227216,3.1068045575753,"GRIA2;RELN;ITPR3;GRIN2C" "103","Prostate cancer","3/97",0.19195865409285,0.419327156998943,0,0,2.03042967670627,3.35117397580249,"NRAS;CCND1;PLAU" "104","Cell adhesion molecules","4/148",0.199270613268433,0.423066892522575,0,0,1.76845819761129,2.85268490854273,"CDH5;CNTN2;NCAM2;ICAM1" "105","Phospholipase D signaling pathway","4/148",0.199270613268433,0.423066892522575,0,0,1.76845819761129,2.85268490854273,"NRAS;SHC3;CXCL8;GAB1" "106","Glycosaminoglycan biosynthesis","2/53",0.199311513810635,0.423066892522575,0,0,2.49229011993147,4.01978054564902,"NDST3;HS3ST5" "107","Viral protein interaction with cytokine and cytokine receptor","3/100",0.203882290734554,0.428724443133407,0,0,1.96733163743473,3.12847527861685,"CXCL8;CCL2;CXCL2" "108","Amoebiasis","3/102",0.211924780218299,0.437459408707497,0,0,1.92739079102715,2.99039283367026,"LAMA5;CXCL8;CXCL2" "109","Chagas disease","3/102",0.211924780218299,0.437459408707497,0,0,1.92739079102715,2.99039283367026,"JUN;CXCL8;CCL2" "110","Protein digestion and absorption","3/103",0.215971847390997,0.44176059693613,0,0,1.90801948051948,2.92424442400828,"COL24A1;COL23A1;COL9A1" "111","Endometrial cancer","2/58",0.227860410248956,0.461879209964099,0,0,2.26918631530282,3.35617664869674,"NRAS;CCND1" "112","VEGF signaling pathway","2/59",0.233607932124668,0.465869184664851,0,0,2.2292624765798,3.24159525090727,"NRAS;KDR" "113","Nitrogen metabolism","1/17",0.233969857187236,0.465869184664851,0,0,3.96633064516129,5.76134509079704,"CPS1" "114","Basal cell carcinoma","2/63",0.256666760856166,0.503813186491586,0,0,2.08265690487559,2.83236483521473,"PTCH1;WNT7B" "115","Human papillomavirus infection","7/331",0.257504517540144,0.503813186491586,0,0,1.37624878167641,1.86718151547958,"LAMA5;NRAS;RELN;CCND2;CCND1;WNT7B;COL9A1" "116","Leukocyte transendothelial migration","3/114",0.261408246475005,0.507041857386862,0,0,1.71797121797122,2.30495376132916,"CDH5;MMP2;ICAM1" "117","Cortisol synthesis and secretion","2/65",0.268215524770852,0.515799086097792,0,0,2.01633533672369,2.65342557151119,"ITPR3;CACNA1H" "118","Pantothenate and CoA biosynthesis","1/21",0.280559060933075,0.533703858866683,0,0,3.17241935483871,4.03205306415009,"BCAT1" "119","Growth hormone synthesis, secretion and action","3/119",0.282465156822802,0.533703858866683,0,0,1.64350089565607,2.0777139550297,"NRAS;SHC3;ITPR3" "120","Mitophagy","2/68",0.285530259384784,0.533703858866683,0,0,1.92438952633127,2.41204381908438,"NRAS;JUN" "121","Thyroid hormone signaling pathway","3/121",0.290931768536392,0.533703858866683,0,0,1.61547985912393,1.99457888236534,"NRAS;PLN;CCND1" "122","Adipocytokine signaling pathway","2/69",0.29129423692827,0.533703858866683,0,0,1.89557069023813,2.33803745301102,"CD36;PPARGC1A" "123","Arginine biosynthesis","1/22",0.291758109513787,0.533703858866683,0,0,3.02119815668203,3.72160316613043,"CPS1" "124","RIG-I-like receptor signaling pathway","2/70",0.297052303008546,0.533783825033686,0,0,1.86759946697125,2.26698010595165,"SIKE1;CXCL8" "125","Mannose type O-glycan biosynthesis","1/23",0.302783381724688,0.533783825033686,0,0,2.88372434017595,3.44529401531398,"FUT9" "126","Protein export","1/23",0.302783381724688,0.533783825033686,0,0,2.88372434017595,3.44529401531398,"SPCS3" "127","Renin-angiotensin system","1/23",0.302783381724688,0.533783825033686,0,0,2.88372434017595,3.44529401531398,"AGTR2" "128","Platelet activation","3/124",0.303663687130275,0.533783825033686,0,0,1.57518514543308,1.87735997233956,"P2RY1;ITPR3;PRKG1" "129","Melanoma","2/72",0.308545912723011,0.534021772020595,0,0,1.81405455386038,2.13311885158981,"NRAS;CCND1" "130","Non-small cell lung cancer","2/72",0.308545912723011,0.534021772020595,0,0,1.81405455386038,2.13311885158981,"NRAS;CCND1" "131","alpha-Linolenic acid metabolism","1/25",0.324323307202112,0.553859545517239,0,0,2.64314516129032,2.97621951022827,"FADS2" "132","Oocyte meiosis","3/129",0.324930933370113,0.553859545517239,0,0,1.51229128014842,1.70003109993166,"CAMK2B;CAMK2D;ITPR3" "133","Pertussis","2/76",0.331411644607857,0.560658797268931,0,0,1.71564768652147,1.89475107456178,"JUN;CXCL8" "134","Leishmaniasis","2/77",0.337096649187786,0.566020493039193,0,0,1.69268608414239,1.84060246797777,"JUN;EEF1A2" "135","Vascular smooth muscle contraction","3/133",0.341948414760638,0.569914024601063,0,0,1.46545954045954,1.57257787318492,"CALCRL;ITPR3;PRKG1" "136","Fatty acid elongation","1/27",0.345199847228398,0.571102688429334,0,0,2.43957816377171,2.59481282168074,"ELOVL6" "137","MicroRNAs in cancer","6/310",0.352052408778527,0.573961135208064,0,0,1.25442191544435,1.30958540253924,"NRAS;CCND2;CCND1;PLAU;SPRY2;SOX4" "138","Butanoate metabolism","1/28",0.355395736984594,0.573961135208064,0,0,2.34910394265233,2.43020289977702,"HMGCS1" "139","Insulin signaling pathway","3/137",0.358933901067433,0.573961135208064,0,0,1.4214237255282,1.45641495180811,"NRAS;SHC3;PPARGC1A" "140","Yersinia infection","3/137",0.358933901067433,0.573961135208064,0,0,1.4214237255282,1.45641495180811,"JUN;CXCL8;CCL2" "141","B cell receptor signaling pathway","2/81",0.359682311397053,0.573961135208064,0,0,1.60665273851952,1.6428572207957,"NRAS;JUN" "142","Measles","3/139",0.36740507867223,0.582155934515857,0,0,1.40037719633308,1.40218407924962,"JUN;CCND2;CCND1" "143","Complement and coagulation cascades","2/85",0.381980142293432,0.597180512819174,0,0,1.52891176355909,1.47140427830676,"PLAU;A2M" "144","Epstein-Barr virus infection","4/202",0.384730747774993,0.597180512819174,0,0,1.28259796663705,1.2251523863343,"JUN;CCND2;CCND1;ICAM1" "145","Circadian rhythm","1/31",0.385043615555974,0.597180512819174,0,0,2.11387096774194,2.01747562738085,"CLOCK" "146","Taste transduction","2/86",0.387503799429331,0.597180512819174,0,0,1.51063337956542,1.43212519673146,"P2RY1;ITPR3" "147","PD-L1 expression and PD-1 checkpoint pathway in cancer","2/89",0.403941758116477,0.61827820119869,0,0,1.45831938399732,1.32194402627553,"NRAS;JUN" "148","Prion disease","5/273",0.419616913615155,0.630250703713797,0,0,1.18409179592235,1.02828082051585,"EGR1;CAV1;ITPR3;NCAM2;GRIN2C" "149","Small cell lung cancer","2/92",0.420167135809198,0.630250703713797,0,0,1.40949298813376,1.22217518192812,"LAMA5;CCND1" "150","Th1 and Th2 cell differentiation","2/92",0.420167135809198,0.630250703713797,0,0,1.40949298813376,1.22217518192812,"JUN;DLL3" "151","Mucin type O-glycan biosynthesis","1/36",0.431466569523958,0.638684066729543,0,0,1.81142857142857,1.52262390364439,"ST6GALNAC3" "152","Tyrosine metabolism","1/36",0.431466569523958,0.638684066729543,0,0,1.81142857142857,1.52262390364439,"TYRP1" "153","Neuroactive ligand-receptor interaction","6/341",0.437809948830194,0.639178822191592,0,0,1.13652067531196,0.938732402189612,"GRIA2;GRID2;CALCRL;P2RY1;AGTR2;GRIN2C" "154","African trypanosomiasis","1/37",0.440323188620875,0.639178822191592,0,0,1.76102150537634,1.44447137771132,"ICAM1" "155","Alanine, aspartate and glutamate metabolism","1/37",0.440323188620875,0.639178822191592,0,0,1.76102150537634,1.44447137771132,"CPS1" "156","Phosphatidylinositol signaling system","2/97",0.446696676574267,0.644274052751346,0,0,1.33496848918413,1.07581838615933,"INPP1;ITPR3" "157","Choline metabolism in cancer","2/98",0.451921323401362,0.646514216387194,0,0,1.32099514563107,1.04919666600379,"JUN;NRAS" "158","Hematopoietic cell lineage","2/99",0.457117878035798,0.646514216387194,0,0,1.30730991225436,1.02338047882486,"CD9;CD36" "159","Various types of N-glycan biosynthesis","1/39",0.457625959424879,0.646514216387194,0,0,1.66816638370119,1.30401085182685,"MGAT4C" "160","Pathways of neurodegeneration","8/475",0.459743442764227,0.646514216387194,0,0,1.08674850354414,0.844497784670128,"CAMK2B;GRIA2;NRAS;CAMK2D;WNT7B;ITPR3;GRIN2C;DNALI1" "161","Glycine, serine and threonine metabolism","1/40",0.466076336106815,0.650847442721731,0,0,1.62531017369727,1.2407712896007,"PIPOX" "162","Longevity regulating pathway","2/102",0.472535170151604,0.650847442721731,0,0,1.26789644012945,0.950469818662892,"NRAS;PPARGC1A" "163","Pancreatic secretion","2/102",0.472535170151604,0.650847442721731,0,0,1.26789644012945,0.950469818662892,"ITPR3;ATP2B1" "164","Ferroptosis","1/41",0.474395469361617,0.650847442721731,0,0,1.58459677419355,1.18165596970451,"SLC39A8" "165","T cell receptor signaling pathway","2/104",0.482666224891514,0.654216268678257,0,0,1.24290881401104,0.905371955509647,"JUN;NRAS" "166","Toll-like receptor signaling pathway","2/104",0.482666224891514,0.654216268678257,0,0,1.24290881401104,0.905371955509647,"JUN;CXCL8" "167","Thermogenesis","4/232",0.488145367783844,0.657680884738712,0,0,1.11212069261101,0.797548494089996,"NRAS;PPARGC1A;COA7;PRKG1" "168","Parathyroid hormone synthesis, secretion and action","2/106",0.492676631184056,0.659834773907217,0,0,1.21888225043565,0.862849476194556,"EGR1;ITPR3" "169","Influenza A","3/172",0.502143105132248,0.663830112870032,0,0,1.12502881733651,0.774998747574245,"CXCL8;CCL2;ICAM1" "170","Insulin resistance","2/108",0.502564171034352,0.663830112870032,0,0,1.19576234963669,0.822722693565647,"CD36;PPARGC1A" "171","ABC transporters","1/45",0.506399738265028,0.663830112870032,0,0,1.44024926686217,0.979987260392447,"ABCA8" "172","HIF-1 signaling pathway","2/109",0.507461241838425,0.663830112870032,0,0,1.18452650999607,0.803505721152779,"CAMK2B;CAMK2D" "173","Chemical carcinogenesis","4/239",0.51132589770372,0.665019231117555,0,0,1.07860558597269,0.723472677077743,"JUN;NRAS;CCND1;DLL3" "174","Salmonella infection","4/249",0.543586992287183,0.699025945137299,0,0,1.03404905936316,0.630320658597454,"JUN;CXCL8;AHNAK;RHOJ" "175","Cysteine and methionine metabolism","1/50",0.543686846217899,0.699025945137299,0,0,1.29295589203423,0.787903851143389,"BCAT1" "176","Endocytosis","4/252",0.55305182857977,0.707026485400274,0,0,1.02138278869392,0.604968661134918,"RAB31;IQSEC1;CAV1;ARAP2" "177","Endocrine and other factor-regulated calcium reabsorption","1/53",0.564697240445351,0.717835475142395,0,0,1.21817617866005,0.696145718811155,"ATP2B1" "178","Cell cycle","2/124",0.577051964570378,0.726744477169511,0,0,1.0380922064831,0.570766926207724,"CCND2;CCND1" "179","Regulation of lipolysis in adipocytes","1/55",0.578165606281522,0.726744477169511,0,0,1.17293906810036,0.642647374815548,"PRKG1" "180","Glutathione metabolism","1/57",0.591218554727363,0.739023193409204,0,0,1.1309331797235,0.5943840140557,"CHAC1" "181","Purine metabolism","2/129",0.598599933894939,0.744115939924648,0,0,0.996967612058202,0.511605688360016,"AMPD1;PDE5A" "182","Notch signaling pathway","1/59",0.603868858871876,0.746541171682265,0,0,1.09182424916574,0.550714214049502,"DLL3" "183","Steroid hormone biosynthesis","1/61",0.616128900118138,0.757535532932137,0,0,1.05532258064516,0.511091759025993,"SRD5A3" "184","Lysine degradation","1/63",0.628010680568343,0.767947843086289,0,0,1.02117585848075,0.475049074629255,"PIPOX" "185","Inflammatory bowel disease","1/65",0.639525834210259,0.777801690255721,0,0,0.989163306451613,0.442183952990311,"JUN" "186","Fc epsilon RI signaling pathway","1/68",0.656135713646153,0.793712556830024,0,0,0.944727973038036,0.398096682381463,"NRAS" "187","Renin secretion","1/69",0.661501024507661,0.795923692589431,0,0,0.930787476280835,0.384642104046138,"ITPR3" "188","Central carbon metabolism in cancer","1/70",0.666782885064628,0.798011431593305,0,0,0.917251051893408,0.37175340868268,"NRAS" "189","Adherens junction","1/71",0.671982589075716,0.799979272709186,0,0,0.904101382488479,0.359400956364518,"YES1" "190","Inositol phosphate metabolism","1/73",0.682140603312908,0.807694760334617,0,0,0.878897849462366,0.336195547621719,"INPP1" "191","Thyroid hormone synthesis","1/75",0.691985023476692,0.807694760334617,0,0,0.855056669572799,0.314824141131998,"ITPR3" "192","mTOR signaling pathway","2/154",0.693957580771792,0.807694760334617,0,0,0.831928121274059,0.303940316208215,"NRAS;WNT7B" "193","Pancreatic cancer","1/76",0.696792663409428,0.807694760334617,0,0,0.843612903225806,0.304769825370869,"CCND1" "194","Non-alcoholic fatty liver disease","2/155",0.697353017929578,0.807694760334617,0,0,0.826448378704232,0.297904487120183,"JUN;CXCL8" "195","Coronavirus disease","3/232",0.702464962187142,0.807694760334617,0,0,0.827709408495435,0.292313651839516,"JUN;CXCL8;CCL2" "196","Hepatitis C","2/157",0.704050543819371,0.807694760334617,0,0,0.815701012631799,0.286233670044506,"NRAS;CCND1" "197","Necroptosis","2/159",0.71062458464279,0.807694760334617,0,0,0.805227464803249,0.275074558652048,"CAMK2B;CAMK2D" "198","RNA degradation","1/79",0.710771389094463,0.807694760334617,0,0,0.811042183622829,0.276893398629445,"DDX6" "199","JAK-STAT signaling pathway","2/162",0.720256782107273,0.814360683287118,0,0,0.790008090614887,0.259239171017941,"CCND2;CCND1" "200","Peroxisome","1/82",0.724107628259649,0.814621081792106,0,0,0.780884109916368,0.252081291220295,"PIPOX" "201","Shigellosis","3/246",0.739238714304627,0.823493317386873,0,0,0.779461279461279,0.235502055687613,"JUN;CXCL8;ITPR3" "202","Tight junction","2/169",0.741686473461429,0.823493317386873,0,0,0.756622676976145,0.226100546448687,"JUN;CCND1" "203","Cardiac muscle contraction","1/87",0.744986292366732,0.823493317386873,0,0,0.73529632408102,0.21646348799178,"CASQ2" "204","Parkinson disease","3/249",0.746633941097432,0.823493317386873,0,0,0.769836870446627,0.224931131305644,"CAMK2B;CAMK2D;ITPR3" "205","Bile secretion","1/90",0.756749532762985,0.830578755471568,0,0,0.710402319681044,0.198005429167254,"HMGCR" "206","Tuberculosis","2/180",0.772524295607066,0.842319902051556,0,0,0.709465110359623,0.183107141616514,"CAMK2B;CAMK2D" "207","Staphylococcus aureus infection","1/95",0.775165109304548,0.842319902051556,0,0,0.672443376801647,0.17125736011492,"ICAM1" "208","Dilated cardiomyopathy","1/96",0.77867795389655,0.842319902051556,0,0,0.665331069609508,0.166437708888274,"PLN" "209","Pathogenic Escherichia coli infection","2/197",0.813874058741274,0.872023700670299,0,0,0.6470500373413,0.133259724802372,"JUN;CXCL8" "210","Th17 cell differentiation","1/107",0.81388878729228,0.872023700670299,0,0,0.595952525867316,0.122725425746371,"JUN" "211","Amyotrophic lateral sclerosis","4/364",0.820543446351643,0.874987087341799,0,0,0.69956568946797,0.138365991556405,"GRIA2;ITPR3;GRIN2C;DNALI1" "212","Toxoplasmosis","1/112",0.827990195232658,0.875252480368693,0,0,0.568962510897995,0.107393930535996,"LAMA5" "213","Alzheimer disease","4/369",0.828572348082363,0.875252480368693,0,0,0.689804114051136,0.129718437434377,"NRAS;WNT7B;ITPR3;GRIN2C" "214","Sphingolipid signaling pathway","1/119",0.845960670709888,0.889444630419274,0,0,0.535019136139967,0.0894992899434268,"NRAS" "215","Regulation of actin cytoskeleton","2/218",0.855620574389132,0.893328554259039,0,0,0.583513124775261,0.0909861835053807,"NRAS;GNG12" "216","Huntington disease","3/306",0.857595412088678,0.893328554259039,0,0,0.623183746946123,0.0957352560443416,"GRIA2;PPARGC1A;DNALI1" "217","Osteoclast differentiation","1/127",0.864217638660685,0.894160857727743,0,0,0.50084485407066,0.0730886127500602,"JUN" "218","Lysosome","1/128",0.866342519931769,0.894160857727743,0,0,0.496875793751588,0.0712892192627464,"CTSF" "219","Autophagy","1/137",0.88403500308124,0.908255140151959,0,0,0.463780834914611,0.0571649861033824,"NRAS" "220","Spliceosome","1/150",0.905549583139499,0.924929202747998,0,0,0.423035289023598,0.0419707039475267,"BCAS2" "221","Phagosome","1/152",0.908486016921367,0.924929202747998,0,0,0.417389446699423,0.0400592788190233,"CD36" "222","RNA transport","1/186",0.946531625740582,0.957521353954769,0,0,0.340087183958152,0.018688095318781,"EEF1A2" "223","Neutrophil extracellular trap formation","1/189",0.949010053030727,0.957521353954769,0,0,0.334608785175017,0.0175120476169323,"CLCN3" "224","Olfactory transduction","3/440",0.968867386416698,0.973192687248916,0,0,0.429106362744807,0.0135715754680581,"CAMK2B;CAMK2D;PRKG1" "225","Herpes simplex virus 1 infection","2/498",0.996648340499496,0.996648340499496,0,0,0.250456728259735,0.000840855592029982,"CCL2;ZNF486"