Supporting Information

Files in this Data Supplement:

Fig. 6. Shown is the time series of total potential energy, backbone H-bond population, and Z coordinates of TMX-3s, TMX-3sH2L, and TMX-3sA2L from the lowest temperature (300 K) ensemble during the REX simulations.

Movie 1. Illustrated is the insertion process for WALP16 peptides shown in Fig. 1. A representative replica is depicted for the peptide, and translation in the XY plane is removed.

Movie 2. Illustrated is the insertion process for WALP19 peptides shown in Fig. 1. A representative replica is depicted for the peptide, and translation in the XY plane is removed.

Movie 3. Illustrated is the insertion process for WALP23 peptides shown in Fig. 1. A representative replica is depicted for the peptide, and translation in the XY plane is removed.

Movie 4. Illustrated is the insertion process for TMX-1 peptides shown in Fig. 5. A representative replica is depicted for the peptide, and translation in the XY plane is removed.

Movie 5. Illustrated is the insertion process for TMX-3sH2L peptides shown in Fig. 5. A representative replica is depicted for the peptide, and translation in the XY plane is removed.