Fig. 1A,,,,
labelname,model,c,lower,upper
Smoking,individual_CRF,0.527,0.502,0.551
Prevalent diabetes,individual_CRF,0.527,0.512,0.541
Exercise,individual_CRF,0.555,0.535,0.575
HDL,individual_CRF,0.575,0.543,0.607
Family history,individual_CRF,0.579,0.553,0.606
BMI,individual_CRF,0.591,0.561,0.620
Total cholesterol,individual_CRF,0.607,0.577,0.637
PRS,PRS,0.626,0.595,0.656
Systolic BP,individual_CRF,0.649,0.619,0.679
Baseline age,individual_CRF,0.719,0.695,0.743
Conventional risk factors,all_crf,0.771,0.748,0.793
PRS + Conventional risk factors,PRS_and_all_crf,0.794,0.771,0.817
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,,,,
Fig. 1B,,,,
labelname,model,c,lower,upper
Smoking,individual_CRF,0.514,0.496,0.532
Exercise,individual_CRF,0.556,0.542,0.571
Total cholesterol,individual_CRF,0.558,0.534,0.582
Family history,individual_CRF,0.591,0.571,0.612
PRS,PRS,0.612,0.589,0.636
Systolic BP,individual_CRF,0.620,0.597,0.643
Baseline age,individual_CRF,0.625,0.605,0.646
HDL,individual_CRF,0.634,0.612,0.657
Triglyceride,individual_CRF,0.698,0.677,0.718
BMI,individual_CRF,0.745,0.726,0.764
Conventional risk factors,all_crf,0.785,0.768,0.802
PRS + Conventional risk factors,PRS_and_all_crf,0.795,0.778,0.812
,,,,
,,,,
Fig. 1C,,,,
labelname,model,c,lower,upper
Prevalent psychiatric disorders,individual_CRF,0.510,0.498,0.522
Prevalent stroke,individual_CRF,0.515,0.503,0.528
HDL,individual_CRF,0.518,0.482,0.554
Diastolic BP,individual_CRF,0.520,0.485,0.554
Prevalent T2D,individual_CRF,0.523,0.508,0.538
Smoking,individual_CRF,0.540,0.518,0.561
Exercise,individual_CRF,0.543,0.521,0.565
Total cholesterol,individual_CRF,0.577,0.543,0.611
BMI,individual_CRF,0.610,0.578,0.642
Alcohol consumption,individual_CRF,0.617,0.584,0.651
PRS,PRS,0.650,0.616,0.684
Systolic BP,individual_CRF,0.656,0.623,0.688
Baseline age,individual_CRF,0.880,0.864,0.895
Conventional risk factors,all_crf,0.883,0.868,0.899
PRS + Conventional risk factors,PRS_and_all_crf,0.900,0.885,0.915
,,,,
,,,,
Fig. 1D,,,,
labelname,model,c,lower,upper
Alcohol consumption,individual_CRF,0.512,0.467,0.557
Exercise,individual_CRF,0.518,0.483,0.553
BMI,individual_CRF,0.544,0.502,0.587
Family history,individual_CRF,0.554,0.513,0.595
Smoking,individual_CRF,0.565,0.534,0.596
PRS,PRS,0.641,0.593,0.690
Baseline age,individual_CRF,0.769,0.739,0.798
Conventional risk factors,all_crf,0.773,0.744,0.802
PRS + Conventional risk factors,PRS_and_all_crf,0.800,0.770,0.831