,Adjusted P-value (EV vs. non-EV),Correlation with EV class,Feature importance (Trained model),Feature importance (Random model) Sequence length,0.0012120426150646,-0.009859448612449903,0.012257546442765822,0.013727335826588 Hydrophobic residues,2.561514764213037e-46,0.08566775767159103,0.013607305736991695,0.0143225703832507 Polar residues,2.977938723255137e-11,0.04577462340332046,0.01028335207888084,0.0151337201441271 Molecular weight,0.0014633742731366,-0.009035929359537433,0.012274439253352679,0.0142986126137289 Helix,8.499189774495478e-36,0.0923639894832667,0.013995130584470272,0.0156719416976896 Turn,1.103622684962311e-158,-0.19937111676639654,0.02506634590919005,0.015213680614561 Sheet,9.93986937144195e-55,0.12770732435656768,0.013884465848295665,0.0143828160542126 A,3.978066971965442e-12,0.034718213574311034,0.012540204296374364,0.0173806904794461 C,3.598801774440196e-81,-0.11658398365274995,0.0206760582894028,0.0173074786852597 D,9.732012241069849e-90,0.14773398987679992,0.013441673713148618,0.0163262117092276 E,9.462417188502445e-08,0.041089157704366,0.010752908176990884,0.0154922981311938 F,2.4221363496940617e-08,0.033182233477999916,0.011133681019369594,0.0168436932065587 G,2.1453894670182653e-06,0.03950079562083921,0.012027645753578696,0.0164685321452827 H,1.9883686710670453e-74,-0.15354778434365762,0.01745308060099126,0.0171432918319243 I,1.1957959904392143e-92,0.1522010425152938,0.014014060228061632,0.0170751971808665 K,4.8985571137257115e-30,0.08207492257090425,0.01114172257244812,0.0160521985172782 L,5.254210324137978e-05,-0.03289527319683268,0.012556800142224827,0.0164067977862815 M,1.596134583925562e-31,0.0822219528766974,0.012182493660595326,0.0173320624513891 N,3.7606597197413286e-30,0.08162425711988484,0.012084508971324837,0.0171206878627192 P,3.61504745761721e-86,-0.14905576849297542,0.014078626979893413,0.0163600055704449 Q,4.2721966887959627e-08,-0.05003225335659897,0.011160327764398726,0.0169200317621194 R,9.09970575397738e-20,-0.062425578302726936,0.01098934634847511,0.0166424000104686 S,2.095083958810809e-154,-0.19018215068055452,0.02209611230765749,0.0167980681580921 T,0.1377385784264783,0.00480154746038329,0.011615126186699038,0.0169705762632259 V,1.7911757019299464e-97,0.15745926368194776,0.01665028579294983,0.0173504671158935 W,6.867632056425098e-11,-0.052335682969762674,0.01187314704101504,0.0159572010892762 Y,4.358910488296032e-30,0.0802373985909112,0.011967595743875226,0.0166809646662868 THSA,6.79432466222242e-39,-0.09427510501918562,0.013651992349959917,0.0154019525977083 TASA,4.3696969162091386e-23,-0.06289079751933736,0.01329910163449414,0.0145572104464576 RHSA,2.944579327912963e-22,-0.05958476357697797,0.01153878201839735,0.0151701058923472 Disorder,6.905731912399665e-136,-0.17777445909361558,0.01861930412385652,0.0158664085112137 Exposed A,0.0022961309886715,-0.03365258016766081,0.01100648285735337,0.0165403091011636 Exposed C,6.501099793654346e-105,-0.12328127459713119,0.014404878350011424,0.0117727255089785 Exposed D,2.0657413324255968e-138,0.19756308592545038,0.015239621687395583,0.0160614785658008 Exposed E,1.4227605892014688e-66,0.13574630124129256,0.01149866480756013,0.015848746051986 Exposed F,9.615197366562031e-10,-0.03316528198771491,0.00949592143400528,0.0143374917824172 Exposed G,0.1392010533525431,0.008055796012822072,0.011352551590549098,0.0167266934333835 Exposed H,1.720774397805001e-38,-0.0923346758961804,0.01261406063083536,0.0167519918291233 Exposed I,1.7957573805102114e-10,-0.032227412639240345,0.009775384715607667,0.014056416631766 Exposed K,1.4073661066036725e-74,0.1449440947836795,0.011678929358703032,0.015721286535354 Exposed L,1.367643133562474e-67,-0.11153351135875036,0.011846412678173377,0.0159965056365204 Exposed M,0.0432184271436168,0.020357652537360393,0.012082177192089228,0.0174618948997566 Exposed N,6.648046463218114e-47,0.10770223192943354,0.011933272372956138,0.0171007329740946 Exposed P,1.2561058986864024e-61,-0.12802755458235976,0.012410658858648348,0.0164398005318005 Exposed Q,0.0010320001780307,0.014977918843921688,0.011147178140178021,0.0174666474847918 Exposed R,3.828458193926645e-06,-0.033682332006739556,0.010965786051781093,0.0170012663416931 Exposed S,5.092747085537546e-111,-0.16790388228879338,0.016638728221836496,0.0168542564004054 Exposed T,0.0001954626461326,-0.029535576805570625,0.011785792069409804,0.0169274114536508 Exposed V,6.500895979355337e-16,-0.04702351651707745,0.011234552305605947,0.0170378538745219 Exposed W,2.0269569208418058e-33,-0.062379423402564096,0.0081045794950782,0.0106089524176532 Exposed Y,0.0121380030185396,-0.0006810092432717995,0.010266967034275423,0.0145404032080319 Probability_solubility,4.697403330790676e-06,0.045619960092847696,0.01227974132679314,0.0150034629528153 Aggregation propensity,6.306466396740119e-18,0.022306565048896315,0.013387368851584114,0.0150519396578141 Aromaticity,1.3756201297810902e-12,0.0424294878481182,0.010632501752705982,0.0157640051043798 Instability index,2.940745958228501e-194,-0.21669272518181745,0.024516165018890573,0.0168679838359605 Gravy,3.865053022587052e-19,0.05168944566276685,0.011428980814106144,0.0143379474344294 Isoelectric point,1.045453053196225e-48,-0.11442077928521703,0.013470464205288702,0.016033412164311 Charge at pH 7,2.2860977173245913e-53,-0.08962247624750068,0.01578859339374856,0.016417526754327 Charge at pH 5,1.9914132785744385e-43,-0.07523986908861292,0.014546977335733135,0.0157240295753194 Exposed polar residues,2.2125928552546745e-115,0.1754633812546335,0.01265293557405391,0.0145916105239915 Exposed hydrophobic residues,2.573768457248478e-46,-0.09223635023702342,0.01118320257121859,0.0147260336403733 HSP¹,1.055095468369183e-12,0.057957442825573004,0.000348418286526007,0.0005205285217065 PTM¹,2.1998596028657257e-199,0.22868864343290277,0.02238464238469826,0.0017968352963408 Citrullination¹,2.8074459403888375e-10,0.05108331564904545,9.196290263535203e-05,0.000107193604954 GPI-anchor¹,0.058340343024033,0.0158190940810745,0.000233284509157244,0.0002340766344892 Nitration¹,3.4256474263259077e-09,0.047762526549988076,6.030959979463322e-05,0.0001195359451642 Prenylation¹,3.795805954150666e-17,0.06836894905720768,0.00022693413414368233,0.0002831259165327 ISGylation¹,1.3237936772996173e-13,0.058412315783536985,3.6175363420946425e-05,0.000158732546959 NEDDylation¹,0.5206901367729354,0.004973559189126828,0.000131938532280179,9.454450410727564e-05 Acetylation¹,5.466725035216234e-240,0.25960038193538054,0.018440802255479817,0.0018664978979148 Glycosylation¹,3.984998745017754e-14,0.060276470265277,0.0054610267819042765,0.0014444498475745 Methylation¹,3.6234657474220384e-163,0.21595746529187415,0.011510575496807075,0.0018066655842358 Myristoylation¹,8.877968824801906e-10,0.04979774336827578,0.0004530115861018359,0.0003455601025089 Nitrosylation¹,1.322971915491516e-207,0.24537980806787738,0.01032989327703291,0.0014057452256854 Palmitoylation¹,0.0,0.4264634406248553,0.07879436094717633,0.0017585877862062 Phosphorylation¹,1.352426027143295e-54,0.11599349342952579,0.0018584993374744223,0.0008151377529216 SUMOylation¹,4.1082415676588356e-15,0.06277757485258258,0.0010899982469088972,0.0014552622506906 Ubiquitination¹,9.081944901201307e-264,0.26461062532722335,0.028245477589307125,0.0017555497008547 PTM predicted,0.172885341254986,-0.010929644686356085,0.00025150173908932154,0.0004368197526739 Phosphorylation predicted,0.0386072920303686,-0.016655926399819592,0.0008865746995475184,0.0011731733294522 Glycosylation predicted,0.0022316572166121,-0.02447259275401366,0.0010466062711001597,0.0013913704756471 Ubiquitination predicted,3.240185922337545e-13,0.0588776665024792,0.0006493663070788638,0.0007891264387206 SUMOylation predicted,0.0615017691001326,0.015000796611325695,0.0014100429946084182,0.0018329255040498 Acetylation predicted,1.092029063344113e-96,0.1670985426041715,0.0026837966024829793,0.0017568969960426 Palmitoylation predicted,0.3224447394838688,-0.007910925601311902,0.0013609744037675136,0.001748801609984 Methylation predicted,0.1362006293761322,-0.012008251793264717,0.001358342186787004,0.0018610026194267 Coiled coil domain,2.843197963758235e-14,0.06110490770663458,0.001795981496232578,0.0013575457764176 RAS profile,7.951071150615765e-16,0.06557659527824129,0.00012074160508397713,0.0001422917700454 WW domain,0.2399145333800333,0.009634344320690979,0.00022413833969119838,0.0001393817268713 EGF,5.140530850804979e-09,0.04767460021108663,0.000873085038677169,0.0004158416425636 RRM,5.208918743173617e-07,0.040914592208939934,0.0002960864747713395,0.0002737506544141 Transmembrane,0.0094786392449535,0.02086660337904521,0.0015345972892807183,0.0013990593549005 TMHMM,0.3851743486218487,-0.00697897142096458,0.0015281510546466418,0.0011679575182061