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. Author manuscript; available in PMC: 2024 Jul 6.
Published in final edited form as: J Med Chem. 2024 Apr 18;67(9):7301–7311. doi: 10.1021/acs.jmedchem.4c00152

Figure 4.

Figure 4.

NPM-ALK degradation properties of Gal-MS99 in senescent Karpas 299 cells. A, C) Western blot analysis of NPM-ALK protein in-Karpas 299 and s-Karpas 299 cells treated with MS99 and Gal-MS99 for 16 h. B, E) Cell viabilities of n-Karpas 299 and s-Karpas 299 cells treated with (B) Gal-MS99 and (E) MS99 for 72 h. D) Structure of Gal-MS99.