Figure 4.

NPM-ALK degradation properties of Gal-MS99 in senescent Karpas 299 cells. A, C) Western blot analysis of NPM-ALK protein in-Karpas 299 and s-Karpas 299 cells treated with MS99 and Gal-MS99 for 16 h. B, E) Cell viabilities of n-Karpas 299 and s-Karpas 299 cells treated with (B) Gal-MS99 and (E) MS99 for 72 h. D) Structure of Gal-MS99.