DOID Description GeneRatio BgRatio pvalue padj geneID geneName EntrezID Count Up Up_Gene_names Down Down_Gene_names DOID:0060180 colitis 16/507 57/6464 4.56128035353359e-06 0.00165802540850946 ENSG00000090339/ENSG00000196611/ENSG00000105426/ENSG00000167207/ENSG00000131196/ENSG00000023445/ENSG00000095752/ENSG00000136244/ENSG00000169429/ENSG00000265972/ENSG00000108576/ENSG00000166828/ENSG00000169194/ENSG00000187796/ENSG00000149968/ENSG00000169245 ICAM1/MMP1/PTPRS/NOD2/NFATC1/BIRC3/IL11/IL6/CXCL8/TXNIP/SLC6A4/SCNN1G/IL13/CARD9/MMP3/CXCL10 3383/4312/5802/64127/4772/330/3589/3569/3576/10628/6532/6340/3596/64170/4314/3627 16 9 ENSG00000090339/ENSG00000105426/ENSG00000167207/ENSG00000131196/ENSG00000023445/ENSG00000136244/ENSG00000169429/ENSG00000187796/ENSG00000169245 7 ENSG00000196611/ENSG00000095752/ENSG00000265972/ENSG00000108576/ENSG00000166828/ENSG00000169194/ENSG00000149968 DOID:8577 ulcerative colitis 16/507 57/6464 4.56128035353359e-06 0.00165802540850946 ENSG00000090339/ENSG00000196611/ENSG00000105426/ENSG00000167207/ENSG00000131196/ENSG00000023445/ENSG00000095752/ENSG00000136244/ENSG00000169429/ENSG00000265972/ENSG00000108576/ENSG00000166828/ENSG00000169194/ENSG00000187796/ENSG00000149968/ENSG00000169245 ICAM1/MMP1/PTPRS/NOD2/NFATC1/BIRC3/IL11/IL6/CXCL8/TXNIP/SLC6A4/SCNN1G/IL13/CARD9/MMP3/CXCL10 3383/4312/5802/64127/4772/330/3589/3569/3576/10628/6532/6340/3596/64170/4314/3627 16 9 ENSG00000090339/ENSG00000105426/ENSG00000167207/ENSG00000131196/ENSG00000023445/ENSG00000136244/ENSG00000169429/ENSG00000187796/ENSG00000169245 7 ENSG00000196611/ENSG00000095752/ENSG00000265972/ENSG00000108576/ENSG00000166828/ENSG00000169194/ENSG00000149968 DOID:2462 retinal vascular disease 14/507 48/6464 1.1103000812644e-05 0.00201797039769805 ENSG00000049130/ENSG00000090339/ENSG00000196611/ENSG00000232810/ENSG00000271503/ENSG00000106366/ENSG00000119630/ENSG00000176697/ENSG00000136244/ENSG00000169429/ENSG00000087245/ENSG00000125378/ENSG00000175567/ENSG00000146674 KITLG/ICAM1/MMP1/TNF/CCL5/SERPINE1/PGF/BDNF/IL6/CXCL8/MMP2/BMP4/UCP2/IGFBP3 4254/3383/4312/7124/6352/5054/5228/627/3569/3576/4313/652/7351/3486 14 8 ENSG00000090339/ENSG00000232810/ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000125378/ENSG00000175567/ENSG00000146674 6 ENSG00000049130/ENSG00000196611/ENSG00000106366/ENSG00000119630/ENSG00000176697/ENSG00000087245 DOID:8947 diabetic retinopathy 14/507 48/6464 1.1103000812644e-05 0.00201797039769805 ENSG00000049130/ENSG00000090339/ENSG00000196611/ENSG00000232810/ENSG00000271503/ENSG00000106366/ENSG00000119630/ENSG00000176697/ENSG00000136244/ENSG00000169429/ENSG00000087245/ENSG00000125378/ENSG00000175567/ENSG00000146674 KITLG/ICAM1/MMP1/TNF/CCL5/SERPINE1/PGF/BDNF/IL6/CXCL8/MMP2/BMP4/UCP2/IGFBP3 4254/3383/4312/7124/6352/5054/5228/627/3569/3576/4313/652/7351/3486 14 8 ENSG00000090339/ENSG00000232810/ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000125378/ENSG00000175567/ENSG00000146674 6 ENSG00000049130/ENSG00000196611/ENSG00000106366/ENSG00000119630/ENSG00000176697/ENSG00000087245 DOID:1492 eye and adnexa disease 58/507 433/6464 2.64220799566495e-05 0.00317586454930191 ENSG00000049130/ENSG00000090339/ENSG00000077942/ENSG00000154277/ENSG00000196611/ENSG00000171812/ENSG00000232810/ENSG00000129038/ENSG00000271503/ENSG00000174804/ENSG00000120949/ENSG00000196754/ENSG00000115414/ENSG00000122691/ENSG00000196116/ENSG00000183876/ENSG00000087088/ENSG00000175806/ENSG00000166033/ENSG00000167207/ENSG00000106366/ENSG00000119630/ENSG00000243649/ENSG00000092969/ENSG00000117115/ENSG00000204390/ENSG00000055332/ENSG00000115415/ENSG00000124762/ENSG00000142227/ENSG00000176697/ENSG00000136450/ENSG00000178573/ENSG00000136244/ENSG00000169429/ENSG00000087245/ENSG00000120738/ENSG00000125730/ENSG00000107165/ENSG00000125378/ENSG00000211445/ENSG00000167995/ENSG00000101115/ENSG00000137462/ENSG00000150627/ENSG00000140470/ENSG00000172349/ENSG00000169194/ENSG00000183770/ENSG00000175567/ENSG00000149968/ENSG00000135437/ENSG00000128656/ENSG00000186765/ENSG00000163635/ENSG00000146674/ENSG00000108255/ENSG00000099953 KITLG/ICAM1/FBLN1/UCHL1/MMP1/COL8A2/TNF/LOXL1/CCL5/FZD4/TNFRSF8/S100A2/FN1/TWIST1/TDRD7/ARSI/BAX/MSRA/HTRA1/NOD2/SERPINE1/PGF/CFB/TGFB2/PADI2/HSPA1L/EIF2AK2/STAT1/CDKN1A/EMP3/BDNF/SRSF1/MAF/IL6/CXCL8/MMP2/EGR1/C3/TYRP1/BMP4/GPX3/BEST1/SALL4/TLR2/WDR17/ADAMTS17/IL16/IL13/FOXL2/UCP2/MMP3/RDH5/CHN1/FSCN2/ATXN7/IGFBP3/CRYBA1/MMP11 4254/3383/2192/7345/4312/1296/7124/4016/6352/8322/943/6273/2335/7291/23424/340075/581/4482/5654/64127/5054/5228/629/7042/11240/3305/5610/6772/1026/2014/627/6426/4094/3569/3576/4313/1958/718/7306/652/2878/7439/57167/7097/116966/170691/3603/3596/668/7351/4314/5959/1123/25794/6314/3486/1411/4320 58 37 ENSG00000090339/ENSG00000077942/ENSG00000154277/ENSG00000171812/ENSG00000232810/ENSG00000129038/ENSG00000271503/ENSG00000174804/ENSG00000120949/ENSG00000196116/ENSG00000183876/ENSG00000167207/ENSG00000243649/ENSG00000092969/ENSG00000117115/ENSG00000204390/ENSG00000055332/ENSG00000115415/ENSG00000136244/ENSG00000169429/ENSG00000120738/ENSG00000125730/ENSG00000107165/ENSG00000125378/ENSG00000211445/ENSG00000167995/ENSG00000101115/ENSG00000137462/ENSG00000140470/ENSG00000172349/ENSG00000183770/ENSG00000175567/ENSG00000135437/ENSG00000186765/ENSG00000163635/ENSG00000146674/ENSG00000099953 21 ENSG00000049130/ENSG00000196611/ENSG00000196754/ENSG00000115414/ENSG00000122691/ENSG00000087088/ENSG00000175806/ENSG00000166033/ENSG00000106366/ENSG00000119630/ENSG00000124762/ENSG00000142227/ENSG00000176697/ENSG00000136450/ENSG00000178573/ENSG00000087245/ENSG00000150627/ENSG00000169194/ENSG00000149968/ENSG00000128656/ENSG00000108255 DOID:288 endometriosis of uterus 6/507 10/6464 3.61484735249673e-05 0.00317586454930191 ENSG00000135679/ENSG00000124762/ENSG00000136244/ENSG00000169429/ENSG00000087245/ENSG00000163464 MDM2/CDKN1A/IL6/CXCL8/MMP2/CXCR1 4193/1026/3569/3576/4313/3577 6 2 ENSG00000136244/ENSG00000169429 4 ENSG00000135679/ENSG00000124762/ENSG00000087245/ENSG00000163464 DOID:4248 coronary stenosis 7/507 14/6464 3.69689911122777e-05 0.00317586454930191 ENSG00000090339/ENSG00000232810/ENSG00000106366/ENSG00000136244/ENSG00000087245/ENSG00000137462/ENSG00000149968 ICAM1/TNF/SERPINE1/IL6/MMP2/TLR2/MMP3 3383/7124/5054/3569/4313/7097/4314 7 4 ENSG00000090339/ENSG00000232810/ENSG00000136244/ENSG00000137462 3 ENSG00000106366/ENSG00000087245/ENSG00000149968 DOID:2723 dermatitis 25/507 135/6464 3.896302281056e-05 0.00317586454930191 ENSG00000049130/ENSG00000090339/ENSG00000232810/ENSG00000271503/ENSG00000168685/ENSG00000167207/ENSG00000124762/ENSG00000072274/ENSG00000176697/ENSG00000008517/ENSG00000166949/ENSG00000151882/ENSG00000136244/ENSG00000162891/ENSG00000164136/ENSG00000162892/ENSG00000137462/ENSG00000108576/ENSG00000128342/ENSG00000006210/ENSG00000143631/ENSG00000172349/ENSG00000169194/ENSG00000134489/ENSG00000169245 KITLG/ICAM1/TNF/CCL5/IL7R/NOD2/CDKN1A/TFRC/BDNF/IL32/SMAD3/CCL28/IL6/IL20/IL15/IL24/TLR2/SLC6A4/LIF/CX3CL1/FLG/IL16/IL13/HRH4/CXCL10 4254/3383/7124/6352/3575/64127/1026/7037/627/9235/4088/56477/3569/50604/3600/11009/7097/6532/3976/6376/2312/3603/3596/59340/3627 25 18 ENSG00000090339/ENSG00000232810/ENSG00000271503/ENSG00000168685/ENSG00000167207/ENSG00000072274/ENSG00000008517/ENSG00000166949/ENSG00000151882/ENSG00000136244/ENSG00000162891/ENSG00000164136/ENSG00000162892/ENSG00000137462/ENSG00000006210/ENSG00000143631/ENSG00000172349/ENSG00000169245 7 ENSG00000049130/ENSG00000124762/ENSG00000176697/ENSG00000108576/ENSG00000128342/ENSG00000169194/ENSG00000134489 DOID:0050589 inflammatory bowel disease 17/507 74/6464 4.18717254490581e-05 0.00317586454930191 ENSG00000090339/ENSG00000196611/ENSG00000105426/ENSG00000271503/ENSG00000167207/ENSG00000131196/ENSG00000023445/ENSG00000095752/ENSG00000136244/ENSG00000169429/ENSG00000265972/ENSG00000108576/ENSG00000166828/ENSG00000169194/ENSG00000187796/ENSG00000149968/ENSG00000169245 ICAM1/MMP1/PTPRS/CCL5/NOD2/NFATC1/BIRC3/IL11/IL6/CXCL8/TXNIP/SLC6A4/SCNN1G/IL13/CARD9/MMP3/CXCL10 3383/4312/5802/6352/64127/4772/330/3589/3569/3576/10628/6532/6340/3596/64170/4314/3627 17 10 ENSG00000090339/ENSG00000105426/ENSG00000271503/ENSG00000167207/ENSG00000131196/ENSG00000023445/ENSG00000136244/ENSG00000169429/ENSG00000187796/ENSG00000169245 7 ENSG00000196611/ENSG00000095752/ENSG00000265972/ENSG00000108576/ENSG00000166828/ENSG00000169194/ENSG00000149968 DOID:2797 idiopathic interstitial pneumonia 9/507 24/6464 4.69719773926774e-05 0.00317586454930191 ENSG00000196611/ENSG00000167207/ENSG00000176697/ENSG00000095752/ENSG00000136244/ENSG00000087245/ENSG00000169194/ENSG00000146674/ENSG00000105255 MMP1/NOD2/BDNF/IL11/IL6/MMP2/IL13/IGFBP3/FSD1 4312/64127/627/3589/3569/4313/3596/3486/79187 9 3 ENSG00000167207/ENSG00000136244/ENSG00000146674 6 ENSG00000196611/ENSG00000176697/ENSG00000095752/ENSG00000087245/ENSG00000169194/ENSG00000105255 DOID:3388 periodontal disease 20/507 97/6464 4.8052971172381e-05 0.00317586454930191 ENSG00000168918/ENSG00000196611/ENSG00000232810/ENSG00000271503/ENSG00000167207/ENSG00000131196/ENSG00000106366/ENSG00000095752/ENSG00000136244/ENSG00000169429/ENSG00000087245/ENSG00000164136/ENSG00000162892/ENSG00000137462/ENSG00000108576/ENSG00000102524/ENSG00000172349/ENSG00000169194/ENSG00000121858/ENSG00000149968 INPP5D/MMP1/TNF/CCL5/NOD2/NFATC1/SERPINE1/IL11/IL6/CXCL8/MMP2/IL15/IL24/TLR2/SLC6A4/TNFSF13B/IL16/IL13/TNFSF10/MMP3 3635/4312/7124/6352/64127/4772/5054/3589/3569/3576/4313/3600/11009/7097/6532/10673/3603/3596/8743/4314 20 11 ENSG00000232810/ENSG00000271503/ENSG00000167207/ENSG00000131196/ENSG00000136244/ENSG00000169429/ENSG00000164136/ENSG00000162892/ENSG00000137462/ENSG00000172349/ENSG00000121858 9 ENSG00000168918/ENSG00000196611/ENSG00000106366/ENSG00000095752/ENSG00000087245/ENSG00000108576/ENSG00000102524/ENSG00000169194/ENSG00000149968 DOID:5614 eye disease 56/507 424/6464 5.50078035573078e-05 0.0033325560988469 ENSG00000049130/ENSG00000090339/ENSG00000077942/ENSG00000154277/ENSG00000196611/ENSG00000171812/ENSG00000232810/ENSG00000129038/ENSG00000271503/ENSG00000174804/ENSG00000120949/ENSG00000196754/ENSG00000115414/ENSG00000122691/ENSG00000196116/ENSG00000183876/ENSG00000087088/ENSG00000175806/ENSG00000166033/ENSG00000167207/ENSG00000106366/ENSG00000119630/ENSG00000243649/ENSG00000092969/ENSG00000117115/ENSG00000204390/ENSG00000055332/ENSG00000115415/ENSG00000124762/ENSG00000142227/ENSG00000176697/ENSG00000178573/ENSG00000136244/ENSG00000169429/ENSG00000087245/ENSG00000120738/ENSG00000125730/ENSG00000107165/ENSG00000125378/ENSG00000211445/ENSG00000167995/ENSG00000101115/ENSG00000137462/ENSG00000150627/ENSG00000140470/ENSG00000172349/ENSG00000169194/ENSG00000175567/ENSG00000149968/ENSG00000135437/ENSG00000128656/ENSG00000186765/ENSG00000163635/ENSG00000146674/ENSG00000108255/ENSG00000099953 KITLG/ICAM1/FBLN1/UCHL1/MMP1/COL8A2/TNF/LOXL1/CCL5/FZD4/TNFRSF8/S100A2/FN1/TWIST1/TDRD7/ARSI/BAX/MSRA/HTRA1/NOD2/SERPINE1/PGF/CFB/TGFB2/PADI2/HSPA1L/EIF2AK2/STAT1/CDKN1A/EMP3/BDNF/MAF/IL6/CXCL8/MMP2/EGR1/C3/TYRP1/BMP4/GPX3/BEST1/SALL4/TLR2/WDR17/ADAMTS17/IL16/IL13/UCP2/MMP3/RDH5/CHN1/FSCN2/ATXN7/IGFBP3/CRYBA1/MMP11 4254/3383/2192/7345/4312/1296/7124/4016/6352/8322/943/6273/2335/7291/23424/340075/581/4482/5654/64127/5054/5228/629/7042/11240/3305/5610/6772/1026/2014/627/4094/3569/3576/4313/1958/718/7306/652/2878/7439/57167/7097/116966/170691/3603/3596/7351/4314/5959/1123/25794/6314/3486/1411/4320 56 36 ENSG00000090339/ENSG00000077942/ENSG00000154277/ENSG00000171812/ENSG00000232810/ENSG00000129038/ENSG00000271503/ENSG00000174804/ENSG00000120949/ENSG00000196116/ENSG00000183876/ENSG00000167207/ENSG00000243649/ENSG00000092969/ENSG00000117115/ENSG00000204390/ENSG00000055332/ENSG00000115415/ENSG00000136244/ENSG00000169429/ENSG00000120738/ENSG00000125730/ENSG00000107165/ENSG00000125378/ENSG00000211445/ENSG00000167995/ENSG00000101115/ENSG00000137462/ENSG00000140470/ENSG00000172349/ENSG00000175567/ENSG00000135437/ENSG00000186765/ENSG00000163635/ENSG00000146674/ENSG00000099953 20 ENSG00000049130/ENSG00000196611/ENSG00000196754/ENSG00000115414/ENSG00000122691/ENSG00000087088/ENSG00000175806/ENSG00000166033/ENSG00000106366/ENSG00000119630/ENSG00000124762/ENSG00000142227/ENSG00000176697/ENSG00000178573/ENSG00000087245/ENSG00000150627/ENSG00000169194/ENSG00000149968/ENSG00000128656/ENSG00000108255 DOID:16 integumentary system disease 44/507 309/6464 6.23100532732756e-05 0.00340995346129178 ENSG00000049130/ENSG00000090339/ENSG00000196611/ENSG00000232810/ENSG00000271503/ENSG00000087088/ENSG00000168685/ENSG00000167207/ENSG00000119630/ENSG00000124762/ENSG00000072274/ENSG00000176697/ENSG00000026025/ENSG00000112964/ENSG00000008517/ENSG00000166949/ENSG00000151882/ENSG00000136244/ENSG00000169429/ENSG00000087245/ENSG00000073111/ENSG00000125730/ENSG00000131080/ENSG00000162891/ENSG00000164136/ENSG00000197506/ENSG00000162892/ENSG00000137462/ENSG00000108576/ENSG00000128342/ENSG00000006210/ENSG00000136695/ENSG00000143631/ENSG00000102524/ENSG00000172349/ENSG00000169194/ENSG00000134760/ENSG00000167768/ENSG00000134489/ENSG00000149968/ENSG00000163736/ENSG00000169245/ENSG00000146674/ENSG00000151623 KITLG/ICAM1/MMP1/TNF/CCL5/BAX/IL7R/NOD2/PGF/CDKN1A/TFRC/BDNF/VIM/GHR/IL32/SMAD3/CCL28/IL6/CXCL8/MMP2/MCM2/C3/EDA2R/IL20/IL15/SLC28A3/IL24/TLR2/SLC6A4/LIF/CX3CL1/IL36RN/FLG/TNFSF13B/IL16/IL13/DSG1/KRT1/HRH4/MMP3/PPBP/CXCL10/IGFBP3/NR3C2 4254/3383/4312/7124/6352/581/3575/64127/5228/1026/7037/627/7431/2690/9235/4088/56477/3569/3576/4313/4171/718/60401/50604/3600/64078/11009/7097/6532/3976/6376/26525/2312/10673/3603/3596/1828/3848/59340/4314/5473/3627/3486/4306 44 27 ENSG00000090339/ENSG00000232810/ENSG00000271503/ENSG00000168685/ENSG00000167207/ENSG00000072274/ENSG00000008517/ENSG00000166949/ENSG00000151882/ENSG00000136244/ENSG00000169429/ENSG00000073111/ENSG00000125730/ENSG00000162891/ENSG00000164136/ENSG00000197506/ENSG00000162892/ENSG00000137462/ENSG00000006210/ENSG00000136695/ENSG00000143631/ENSG00000172349/ENSG00000134760/ENSG00000167768/ENSG00000169245/ENSG00000146674/ENSG00000151623 17 ENSG00000049130/ENSG00000196611/ENSG00000087088/ENSG00000119630/ENSG00000124762/ENSG00000176697/ENSG00000026025/ENSG00000112964/ENSG00000087245/ENSG00000131080/ENSG00000108576/ENSG00000128342/ENSG00000102524/ENSG00000169194/ENSG00000134489/ENSG00000149968/ENSG00000163736 DOID:37 skin disease 40/507 272/6464 6.56662289657289e-05 0.00340995346129178 ENSG00000049130/ENSG00000090339/ENSG00000196611/ENSG00000232810/ENSG00000271503/ENSG00000087088/ENSG00000168685/ENSG00000167207/ENSG00000119630/ENSG00000124762/ENSG00000072274/ENSG00000176697/ENSG00000026025/ENSG00000112964/ENSG00000008517/ENSG00000166949/ENSG00000151882/ENSG00000136244/ENSG00000169429/ENSG00000087245/ENSG00000073111/ENSG00000125730/ENSG00000162891/ENSG00000164136/ENSG00000197506/ENSG00000162892/ENSG00000137462/ENSG00000108576/ENSG00000128342/ENSG00000006210/ENSG00000143631/ENSG00000172349/ENSG00000169194/ENSG00000134760/ENSG00000167768/ENSG00000134489/ENSG00000149968/ENSG00000163736/ENSG00000169245/ENSG00000146674 KITLG/ICAM1/MMP1/TNF/CCL5/BAX/IL7R/NOD2/PGF/CDKN1A/TFRC/BDNF/VIM/GHR/IL32/SMAD3/CCL28/IL6/CXCL8/MMP2/MCM2/C3/IL20/IL15/SLC28A3/IL24/TLR2/SLC6A4/LIF/CX3CL1/FLG/IL16/IL13/DSG1/KRT1/HRH4/MMP3/PPBP/CXCL10/IGFBP3 4254/3383/4312/7124/6352/581/3575/64127/5228/1026/7037/627/7431/2690/9235/4088/56477/3569/3576/4313/4171/718/50604/3600/64078/11009/7097/6532/3976/6376/2312/3603/3596/1828/3848/59340/4314/5473/3627/3486 40 25 ENSG00000090339/ENSG00000232810/ENSG00000271503/ENSG00000168685/ENSG00000167207/ENSG00000072274/ENSG00000008517/ENSG00000166949/ENSG00000151882/ENSG00000136244/ENSG00000169429/ENSG00000073111/ENSG00000125730/ENSG00000162891/ENSG00000164136/ENSG00000197506/ENSG00000162892/ENSG00000137462/ENSG00000006210/ENSG00000143631/ENSG00000172349/ENSG00000134760/ENSG00000167768/ENSG00000169245/ENSG00000146674 15 ENSG00000049130/ENSG00000196611/ENSG00000087088/ENSG00000119630/ENSG00000124762/ENSG00000176697/ENSG00000026025/ENSG00000112964/ENSG00000087245/ENSG00000108576/ENSG00000128342/ENSG00000169194/ENSG00000134489/ENSG00000149968/ENSG00000163736 DOID:0050155 sensory system disease 61/507 480/6464 7.9523196421172e-05 0.0038542242532128 ENSG00000049130/ENSG00000090339/ENSG00000077942/ENSG00000154277/ENSG00000196611/ENSG00000171812/ENSG00000232810/ENSG00000129038/ENSG00000271503/ENSG00000174804/ENSG00000120949/ENSG00000196754/ENSG00000115414/ENSG00000122691/ENSG00000196116/ENSG00000183876/ENSG00000087088/ENSG00000175806/ENSG00000166033/ENSG00000167207/ENSG00000106366/ENSG00000119630/ENSG00000243649/ENSG00000092969/ENSG00000117115/ENSG00000204390/ENSG00000055332/ENSG00000115415/ENSG00000124762/ENSG00000142227/ENSG00000176697/ENSG00000136450/ENSG00000178573/ENSG00000136244/ENSG00000169429/ENSG00000087245/ENSG00000120738/ENSG00000125730/ENSG00000107165/ENSG00000125378/ENSG00000211445/ENSG00000091536/ENSG00000167995/ENSG00000101115/ENSG00000137462/ENSG00000150627/ENSG00000140470/ENSG00000117013/ENSG00000121742/ENSG00000172349/ENSG00000169194/ENSG00000183770/ENSG00000175567/ENSG00000149968/ENSG00000135437/ENSG00000128656/ENSG00000186765/ENSG00000163635/ENSG00000146674/ENSG00000108255/ENSG00000099953 KITLG/ICAM1/FBLN1/UCHL1/MMP1/COL8A2/TNF/LOXL1/CCL5/FZD4/TNFRSF8/S100A2/FN1/TWIST1/TDRD7/ARSI/BAX/MSRA/HTRA1/NOD2/SERPINE1/PGF/CFB/TGFB2/PADI2/HSPA1L/EIF2AK2/STAT1/CDKN1A/EMP3/BDNF/SRSF1/MAF/IL6/CXCL8/MMP2/EGR1/C3/TYRP1/BMP4/GPX3/MYO15A/BEST1/SALL4/TLR2/WDR17/ADAMTS17/KCNQ4/GJB6/IL16/IL13/FOXL2/UCP2/MMP3/RDH5/CHN1/FSCN2/ATXN7/IGFBP3/CRYBA1/MMP11 4254/3383/2192/7345/4312/1296/7124/4016/6352/8322/943/6273/2335/7291/23424/340075/581/4482/5654/64127/5054/5228/629/7042/11240/3305/5610/6772/1026/2014/627/6426/4094/3569/3576/4313/1958/718/7306/652/2878/51168/7439/57167/7097/116966/170691/9132/10804/3603/3596/668/7351/4314/5959/1123/25794/6314/3486/1411/4320 61 40 ENSG00000090339/ENSG00000077942/ENSG00000154277/ENSG00000171812/ENSG00000232810/ENSG00000129038/ENSG00000271503/ENSG00000174804/ENSG00000120949/ENSG00000196116/ENSG00000183876/ENSG00000167207/ENSG00000243649/ENSG00000092969/ENSG00000117115/ENSG00000204390/ENSG00000055332/ENSG00000115415/ENSG00000136244/ENSG00000169429/ENSG00000120738/ENSG00000125730/ENSG00000107165/ENSG00000125378/ENSG00000211445/ENSG00000091536/ENSG00000167995/ENSG00000101115/ENSG00000137462/ENSG00000140470/ENSG00000117013/ENSG00000121742/ENSG00000172349/ENSG00000183770/ENSG00000175567/ENSG00000135437/ENSG00000186765/ENSG00000163635/ENSG00000146674/ENSG00000099953 21 ENSG00000049130/ENSG00000196611/ENSG00000196754/ENSG00000115414/ENSG00000122691/ENSG00000087088/ENSG00000175806/ENSG00000166033/ENSG00000106366/ENSG00000119630/ENSG00000124762/ENSG00000142227/ENSG00000176697/ENSG00000136450/ENSG00000178573/ENSG00000087245/ENSG00000150627/ENSG00000169194/ENSG00000149968/ENSG00000128656/ENSG00000108255 DOID:8469 influenza 19/507 94/6464 9.82394874234151e-05 0.00416544369593072 ENSG00000090339/ENSG00000185507/ENSG00000187608/ENSG00000115267/ENSG00000232810/ENSG00000271503/ENSG00000107201/ENSG00000087088/ENSG00000106366/ENSG00000055332/ENSG00000115415/ENSG00000130303/ENSG00000008517/ENSG00000169429/ENSG00000185885/ENSG00000157601/ENSG00000137648/ENSG00000121858/ENSG00000169245 ICAM1/IRF7/ISG15/IFIH1/TNF/CCL5/DDX58/BAX/SERPINE1/EIF2AK2/STAT1/BST2/IL32/CXCL8/IFITM1/MX1/TMPRSS4/TNFSF10/CXCL10 3383/3665/9636/64135/7124/6352/23586/581/5054/5610/6772/684/9235/3576/8519/4599/56649/8743/3627 19 17 ENSG00000090339/ENSG00000185507/ENSG00000187608/ENSG00000115267/ENSG00000232810/ENSG00000271503/ENSG00000107201/ENSG00000055332/ENSG00000115415/ENSG00000130303/ENSG00000008517/ENSG00000169429/ENSG00000185885/ENSG00000157601/ENSG00000137648/ENSG00000121858/ENSG00000169245 2 ENSG00000087088/ENSG00000106366 DOID:640 encephalomyelitis 7/507 16/6464 0.000107221285656461 0.00416544369593072 ENSG00000090339/ENSG00000232810/ENSG00000125347/ENSG00000125730/ENSG00000137462/ENSG00000172349/ENSG00000169245 ICAM1/TNF/IRF1/C3/TLR2/IL16/CXCL10 3383/7124/3659/718/7097/3603/3627 7 7 ENSG00000090339/ENSG00000232810/ENSG00000125347/ENSG00000125730/ENSG00000137462/ENSG00000172349/ENSG00000169245 0 DOID:289 endometriosis 16/507 72/6464 0.000107377032985755 0.00416544369593072 ENSG00000090339/ENSG00000196611/ENSG00000271503/ENSG00000135679/ENSG00000124762/ENSG00000095752/ENSG00000136244/ENSG00000169429/ENSG00000087245/ENSG00000164136/ENSG00000128342/ENSG00000172349/ENSG00000163464/ENSG00000149968/ENSG00000146674/ENSG00000086696 ICAM1/MMP1/CCL5/MDM2/CDKN1A/IL11/IL6/CXCL8/MMP2/IL15/LIF/IL16/CXCR1/MMP3/IGFBP3/HSD17B2 3383/4312/6352/4193/1026/3589/3569/3576/4313/3600/3976/3603/3577/4314/3486/3294 16 7 ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000164136/ENSG00000172349/ENSG00000146674 9 ENSG00000196611/ENSG00000135679/ENSG00000124762/ENSG00000095752/ENSG00000087245/ENSG00000128342/ENSG00000163464/ENSG00000149968/ENSG00000086696 DOID:824 periodontitis 18/507 87/6464 0.000108863040196264 0.00416544369593072 ENSG00000168918/ENSG00000196611/ENSG00000232810/ENSG00000271503/ENSG00000167207/ENSG00000131196/ENSG00000106366/ENSG00000095752/ENSG00000136244/ENSG00000169429/ENSG00000087245/ENSG00000162892/ENSG00000137462/ENSG00000108576/ENSG00000102524/ENSG00000172349/ENSG00000169194/ENSG00000149968 INPP5D/MMP1/TNF/CCL5/NOD2/NFATC1/SERPINE1/IL11/IL6/CXCL8/MMP2/IL24/TLR2/SLC6A4/TNFSF13B/IL16/IL13/MMP3 3635/4312/7124/6352/64127/4772/5054/3589/3569/3576/4313/11009/7097/6532/10673/3603/3596/4314 18 9 ENSG00000232810/ENSG00000271503/ENSG00000167207/ENSG00000131196/ENSG00000136244/ENSG00000169429/ENSG00000162892/ENSG00000137462/ENSG00000172349 9 ENSG00000168918/ENSG00000196611/ENSG00000106366/ENSG00000095752/ENSG00000087245/ENSG00000108576/ENSG00000102524/ENSG00000169194/ENSG00000149968 DOID:15 reproductive system disease 41/507 289/6464 0.000121208549410669 0.00423246176567621 ENSG00000049130/ENSG00000090339/ENSG00000006047/ENSG00000139618/ENSG00000126803/ENSG00000196611/ENSG00000232810/ENSG00000271503/ENSG00000135679/ENSG00000099139/ENSG00000007038/ENSG00000106366/ENSG00000124762/ENSG00000176697/ENSG00000095752/ENSG00000163083/ENSG00000126733/ENSG00000196139/ENSG00000178919/ENSG00000136244/ENSG00000169429/ENSG00000087245/ENSG00000125730/ENSG00000164136/ENSG00000211445/ENSG00000012048/ENSG00000101115/ENSG00000137462/ENSG00000105146/ENSG00000204531/ENSG00000128342/ENSG00000006210/ENSG00000167034/ENSG00000169679/ENSG00000172349/ENSG00000183770/ENSG00000163464/ENSG00000130005/ENSG00000149968/ENSG00000146674/ENSG00000086696 KITLG/ICAM1/YBX2/BRCA2/HSPA2/MMP1/TNF/CCL5/MDM2/PCSK5/PRSS21/SERPINE1/CDKN1A/BDNF/IL11/INHBB/DACH2/AKR1C3/FOXE1/IL6/CXCL8/MMP2/C3/IL15/GPX3/BRCA1/SALL4/TLR2/AURKC/POU5F1/LIF/CX3CL1/NKX3-1/BUB1/IL16/FOXL2/CXCR1/GAMT/MMP3/IGFBP3/HSD17B2 4254/3383/51087/675/3306/4312/7124/6352/4193/5125/10942/5054/1026/627/3589/3625/117154/8644/2304/3569/3576/4313/718/3600/2878/672/57167/7097/6795/5460/3976/6376/4824/699/3603/668/3577/2593/4314/3486/3294 41 23 ENSG00000090339/ENSG00000006047/ENSG00000139618/ENSG00000126803/ENSG00000232810/ENSG00000271503/ENSG00000099139/ENSG00000007038/ENSG00000178919/ENSG00000136244/ENSG00000169429/ENSG00000125730/ENSG00000164136/ENSG00000211445/ENSG00000012048/ENSG00000101115/ENSG00000137462/ENSG00000204531/ENSG00000006210/ENSG00000169679/ENSG00000172349/ENSG00000183770/ENSG00000146674 18 ENSG00000049130/ENSG00000196611/ENSG00000135679/ENSG00000106366/ENSG00000124762/ENSG00000176697/ENSG00000095752/ENSG00000163083/ENSG00000126733/ENSG00000196139/ENSG00000087245/ENSG00000105146/ENSG00000128342/ENSG00000167034/ENSG00000163464/ENSG00000130005/ENSG00000149968/ENSG00000086696 DOID:9588 encephalitis 12/507 45/6464 0.000124158843982904 0.00423246176567621 ENSG00000187608/ENSG00000134321/ENSG00000055332/ENSG00000115415/ENSG00000008517/ENSG00000111331/ENSG00000136244/ENSG00000169429/ENSG00000174469/ENSG00000111335/ENSG00000006210/ENSG00000121858 ISG15/RSAD2/EIF2AK2/STAT1/IL32/OAS3/IL6/CXCL8/CNTNAP2/OAS2/CX3CL1/TNFSF10 9636/91543/5610/6772/9235/4940/3569/3576/26047/4939/6376/8743 12 11 ENSG00000187608/ENSG00000134321/ENSG00000055332/ENSG00000115415/ENSG00000008517/ENSG00000111331/ENSG00000136244/ENSG00000169429/ENSG00000111335/ENSG00000006210/ENSG00000121858 1 ENSG00000174469 DOID:0050161 lower respiratory tract disease 52/507 397/6464 0.000128079998411109 0.00423246176567621 ENSG00000090339/ENSG00000103811/ENSG00000196611/ENSG00000115267/ENSG00000232810/ENSG00000271503/ENSG00000120949/ENSG00000125347/ENSG00000122691/ENSG00000087088/ENSG00000145147/ENSG00000175806/ENSG00000167207/ENSG00000106366/ENSG00000119630/ENSG00000055332/ENSG00000115415/ENSG00000169248/ENSG00000149948/ENSG00000113810/ENSG00000136824/ENSG00000176697/ENSG00000095752/ENSG00000189143/ENSG00000166949/ENSG00000178573/ENSG00000151882/ENSG00000136244/ENSG00000169429/ENSG00000087245/ENSG00000165949/ENSG00000140279/ENSG00000156804/ENSG00000167972/ENSG00000137462/ENSG00000108576/ENSG00000163131/ENSG00000006210/ENSG00000166828/ENSG00000172349/ENSG00000169194/ENSG00000163464/ENSG00000124731/ENSG00000173585/ENSG00000149968/ENSG00000065989/ENSG00000128271/ENSG00000169245/ENSG00000146674/ENSG00000169896/ENSG00000105255/ENSG00000130234 ICAM1/CTSH/MMP1/IFIH1/TNF/CCL5/TNFRSF8/IRF1/TWIST1/BAX/SLIT2/MSRA/NOD2/SERPINE1/PGF/EIF2AK2/STAT1/CXCL11/HMGA2/SMC4/SMC2/BDNF/IL11/CLDN4/SMAD3/MAF/CCL28/IL6/CXCL8/MMP2/IFI27/DUOX2/FBXO32/ABCA3/TLR2/SLC6A4/CTSS/CX3CL1/SCNN1G/IL16/IL13/CXCR1/TREM1/CCR9/MMP3/PDE4A/ADORA2A/CXCL10/IGFBP3/ITGAM/FSD1/ACE2 3383/1512/4312/64135/7124/6352/943/3659/7291/581/9353/4482/64127/5054/5228/5610/6772/6373/8091/10051/10592/627/3589/1364/4088/4094/56477/3569/3576/4313/3429/50506/114907/21/7097/6532/1520/6376/6340/3603/3596/3577/54210/10803/4314/5141/135/3627/3486/3684/79187/59272 52 32 ENSG00000090339/ENSG00000103811/ENSG00000115267/ENSG00000232810/ENSG00000271503/ENSG00000120949/ENSG00000125347/ENSG00000145147/ENSG00000167207/ENSG00000055332/ENSG00000115415/ENSG00000169248/ENSG00000113810/ENSG00000136824/ENSG00000189143/ENSG00000166949/ENSG00000151882/ENSG00000136244/ENSG00000169429/ENSG00000140279/ENSG00000156804/ENSG00000167972/ENSG00000137462/ENSG00000163131/ENSG00000006210/ENSG00000172349/ENSG00000173585/ENSG00000065989/ENSG00000128271/ENSG00000169245/ENSG00000146674/ENSG00000130234 20 ENSG00000196611/ENSG00000122691/ENSG00000087088/ENSG00000175806/ENSG00000106366/ENSG00000119630/ENSG00000149948/ENSG00000176697/ENSG00000095752/ENSG00000178573/ENSG00000087245/ENSG00000165949/ENSG00000108576/ENSG00000166828/ENSG00000169194/ENSG00000163464/ENSG00000124731/ENSG00000149968/ENSG00000169896/ENSG00000105255 DOID:229 female reproductive system disease 25/507 147/6464 0.000164519915628165 0.005200259941812 ENSG00000049130/ENSG00000090339/ENSG00000196611/ENSG00000232810/ENSG00000271503/ENSG00000135679/ENSG00000124762/ENSG00000095752/ENSG00000163083/ENSG00000126733/ENSG00000178919/ENSG00000136244/ENSG00000169429/ENSG00000087245/ENSG00000164136/ENSG00000101115/ENSG00000137462/ENSG00000204531/ENSG00000128342/ENSG00000172349/ENSG00000183770/ENSG00000163464/ENSG00000149968/ENSG00000146674/ENSG00000086696 KITLG/ICAM1/MMP1/TNF/CCL5/MDM2/CDKN1A/IL11/INHBB/DACH2/FOXE1/IL6/CXCL8/MMP2/IL15/SALL4/TLR2/POU5F1/LIF/IL16/FOXL2/CXCR1/MMP3/IGFBP3/HSD17B2 4254/3383/4312/7124/6352/4193/1026/3589/3625/117154/2304/3569/3576/4313/3600/57167/7097/5460/3976/3603/668/3577/4314/3486/3294 25 13 ENSG00000090339/ENSG00000232810/ENSG00000271503/ENSG00000178919/ENSG00000136244/ENSG00000169429/ENSG00000164136/ENSG00000101115/ENSG00000137462/ENSG00000204531/ENSG00000172349/ENSG00000183770/ENSG00000146674 12 ENSG00000049130/ENSG00000196611/ENSG00000135679/ENSG00000124762/ENSG00000095752/ENSG00000163083/ENSG00000126733/ENSG00000087245/ENSG00000128342/ENSG00000163464/ENSG00000149968/ENSG00000086696 DOID:1176 bronchial disease 21/507 114/6464 0.000173742259745122 0.00526294261811266 ENSG00000090339/ENSG00000196611/ENSG00000232810/ENSG00000271503/ENSG00000125347/ENSG00000087088/ENSG00000106366/ENSG00000055332/ENSG00000176697/ENSG00000178573/ENSG00000151882/ENSG00000169429/ENSG00000087245/ENSG00000137462/ENSG00000006210/ENSG00000166828/ENSG00000172349/ENSG00000169194/ENSG00000163464/ENSG00000173585/ENSG00000169245 ICAM1/MMP1/TNF/CCL5/IRF1/BAX/SERPINE1/EIF2AK2/BDNF/MAF/CCL28/CXCL8/MMP2/TLR2/CX3CL1/SCNN1G/IL16/IL13/CXCR1/CCR9/CXCL10 3383/4312/7124/6352/3659/581/5054/5610/627/4094/56477/3576/4313/7097/6376/6340/3603/3596/3577/10803/3627 21 12 ENSG00000090339/ENSG00000232810/ENSG00000271503/ENSG00000125347/ENSG00000055332/ENSG00000151882/ENSG00000169429/ENSG00000137462/ENSG00000006210/ENSG00000172349/ENSG00000173585/ENSG00000169245 9 ENSG00000196611/ENSG00000087088/ENSG00000106366/ENSG00000176697/ENSG00000178573/ENSG00000087245/ENSG00000166828/ENSG00000169194/ENSG00000163464 DOID:2030 anxiety disorder 12/507 48/6464 0.000242026798831878 0.00703813931003102 ENSG00000146477/ENSG00000116741/ENSG00000069482/ENSG00000176697/ENSG00000136244/ENSG00000169429/ENSG00000174469/ENSG00000198929/ENSG00000108576/ENSG00000125510/ENSG00000128271/ENSG00000149295 SLC22A3/RGS2/GAL/BDNF/IL6/CXCL8/CNTNAP2/NOS1AP/SLC6A4/OPRL1/ADORA2A/DRD2 6581/5997/51083/627/3569/3576/26047/9722/6532/4987/135/1813 12 7 ENSG00000146477/ENSG00000069482/ENSG00000136244/ENSG00000169429/ENSG00000198929/ENSG00000125510/ENSG00000128271 5 ENSG00000116741/ENSG00000176697/ENSG00000174469/ENSG00000108576/ENSG00000149295 DOID:10933 obsessive-compulsive disorder 7/507 18/6464 0.00025960837154396 0.00714369977961952 ENSG00000146477/ENSG00000176697/ENSG00000136244/ENSG00000174469/ENSG00000198929/ENSG00000108576/ENSG00000149295 SLC22A3/BDNF/IL6/CNTNAP2/NOS1AP/SLC6A4/DRD2 6581/627/3569/26047/9722/6532/1813 7 3 ENSG00000146477/ENSG00000136244/ENSG00000198929 4 ENSG00000176697/ENSG00000174469/ENSG00000108576/ENSG00000149295 DOID:1579 respiratory system disease 55/507 439/6464 0.000265309345322871 0.00714369977961952 ENSG00000090339/ENSG00000103811/ENSG00000196611/ENSG00000115267/ENSG00000232810/ENSG00000271503/ENSG00000120949/ENSG00000125347/ENSG00000122691/ENSG00000087088/ENSG00000145147/ENSG00000175806/ENSG00000137033/ENSG00000167207/ENSG00000106366/ENSG00000119630/ENSG00000055332/ENSG00000115415/ENSG00000169248/ENSG00000149948/ENSG00000113810/ENSG00000136824/ENSG00000176697/ENSG00000095752/ENSG00000189143/ENSG00000166949/ENSG00000178573/ENSG00000151882/ENSG00000136244/ENSG00000169429/ENSG00000087245/ENSG00000076706/ENSG00000165949/ENSG00000140279/ENSG00000156804/ENSG00000167972/ENSG00000137462/ENSG00000108576/ENSG00000163131/ENSG00000006210/ENSG00000143631/ENSG00000166828/ENSG00000172349/ENSG00000169194/ENSG00000163464/ENSG00000124731/ENSG00000173585/ENSG00000149968/ENSG00000065989/ENSG00000128271/ENSG00000169245/ENSG00000146674/ENSG00000169896/ENSG00000105255/ENSG00000130234 ICAM1/CTSH/MMP1/IFIH1/TNF/CCL5/TNFRSF8/IRF1/TWIST1/BAX/SLIT2/MSRA/IL33/NOD2/SERPINE1/PGF/EIF2AK2/STAT1/CXCL11/HMGA2/SMC4/SMC2/BDNF/IL11/CLDN4/SMAD3/MAF/CCL28/IL6/CXCL8/MMP2/MCAM/IFI27/DUOX2/FBXO32/ABCA3/TLR2/SLC6A4/CTSS/CX3CL1/FLG/SCNN1G/IL16/IL13/CXCR1/TREM1/CCR9/MMP3/PDE4A/ADORA2A/CXCL10/IGFBP3/ITGAM/FSD1/ACE2 3383/1512/4312/64135/7124/6352/943/3659/7291/581/9353/4482/90865/64127/5054/5228/5610/6772/6373/8091/10051/10592/627/3589/1364/4088/4094/56477/3569/3576/4313/4162/3429/50506/114907/21/7097/6532/1520/6376/2312/6340/3603/3596/3577/54210/10803/4314/5141/135/3627/3486/3684/79187/59272 55 34 ENSG00000090339/ENSG00000103811/ENSG00000115267/ENSG00000232810/ENSG00000271503/ENSG00000120949/ENSG00000125347/ENSG00000145147/ENSG00000167207/ENSG00000055332/ENSG00000115415/ENSG00000169248/ENSG00000113810/ENSG00000136824/ENSG00000189143/ENSG00000166949/ENSG00000151882/ENSG00000136244/ENSG00000169429/ENSG00000076706/ENSG00000140279/ENSG00000156804/ENSG00000167972/ENSG00000137462/ENSG00000163131/ENSG00000006210/ENSG00000143631/ENSG00000172349/ENSG00000173585/ENSG00000065989/ENSG00000128271/ENSG00000169245/ENSG00000146674/ENSG00000130234 21 ENSG00000196611/ENSG00000122691/ENSG00000087088/ENSG00000175806/ENSG00000137033/ENSG00000106366/ENSG00000119630/ENSG00000149948/ENSG00000176697/ENSG00000095752/ENSG00000178573/ENSG00000087245/ENSG00000165949/ENSG00000108576/ENSG00000166828/ENSG00000169194/ENSG00000163464/ENSG00000124731/ENSG00000149968/ENSG00000169896/ENSG00000105255 DOID:381 arthropathy 15/507 71/6464 0.000317134765821064 0.00823417766971119 ENSG00000126803/ENSG00000196611/ENSG00000232810/ENSG00000167207/ENSG00000101347/ENSG00000136244/ENSG00000169429/ENSG00000087245/ENSG00000125378/ENSG00000162891/ENSG00000162892/ENSG00000187796/ENSG00000173432/ENSG00000121858/ENSG00000149968 HSPA2/MMP1/TNF/NOD2/SAMHD1/IL6/CXCL8/MMP2/BMP4/IL20/IL24/CARD9/SAA1/TNFSF10/MMP3 3306/4312/7124/64127/25939/3569/3576/4313/652/50604/11009/64170/6288/8743/4314 15 12 ENSG00000126803/ENSG00000232810/ENSG00000167207/ENSG00000101347/ENSG00000136244/ENSG00000169429/ENSG00000125378/ENSG00000162891/ENSG00000162892/ENSG00000187796/ENSG00000173432/ENSG00000121858 3 ENSG00000196611/ENSG00000087245/ENSG00000149968 DOID:5295 intestinal disease 22/507 129/6464 0.000385679115368698 0.00947823157425445 ENSG00000090339/ENSG00000196611/ENSG00000105426/ENSG00000271503/ENSG00000167207/ENSG00000131196/ENSG00000119888/ENSG00000023445/ENSG00000095752/ENSG00000136244/ENSG00000169429/ENSG00000185885/ENSG00000164136/ENSG00000265972/ENSG00000108576/ENSG00000166828/ENSG00000172349/ENSG00000169194/ENSG00000187796/ENSG00000121858/ENSG00000149968/ENSG00000169245 ICAM1/MMP1/PTPRS/CCL5/NOD2/NFATC1/EPCAM/BIRC3/IL11/IL6/CXCL8/IFITM1/IL15/TXNIP/SLC6A4/SCNN1G/IL16/IL13/CARD9/TNFSF10/MMP3/CXCL10 3383/4312/5802/6352/64127/4772/4072/330/3589/3569/3576/8519/3600/10628/6532/6340/3603/3596/64170/8743/4314/3627 22 15 ENSG00000090339/ENSG00000105426/ENSG00000271503/ENSG00000167207/ENSG00000131196/ENSG00000119888/ENSG00000023445/ENSG00000136244/ENSG00000169429/ENSG00000185885/ENSG00000164136/ENSG00000172349/ENSG00000187796/ENSG00000121858/ENSG00000169245 7 ENSG00000196611/ENSG00000095752/ENSG00000265972/ENSG00000108576/ENSG00000166828/ENSG00000169194/ENSG00000149968 DOID:7148 rheumatoid arthritis 54/507 436/6464 0.000403772645590083 0.00947823157425445 ENSG00000090339/ENSG00000078081/ENSG00000196611/ENSG00000115267/ENSG00000232810/ENSG00000271503/ENSG00000135679/ENSG00000120949/ENSG00000115414/ENSG00000198719/ENSG00000168685/ENSG00000175806/ENSG00000137033/ENSG00000167207/ENSG00000131196/ENSG00000106366/ENSG00000133321/ENSG00000117115/ENSG00000124762/ENSG00000026025/ENSG00000008517/ENSG00000136244/ENSG00000169429/ENSG00000087245/ENSG00000120738/ENSG00000151849/ENSG00000185052/ENSG00000165078/ENSG00000027869/ENSG00000181634/ENSG00000125378/ENSG00000162891/ENSG00000164136/ENSG00000196154/ENSG00000130513/ENSG00000162892/ENSG00000137462/ENSG00000163131/ENSG00000006210/ENSG00000263528/ENSG00000143631/ENSG00000102524/ENSG00000172349/ENSG00000169194/ENSG00000173432/ENSG00000124731/ENSG00000173585/ENSG00000170989/ENSG00000134489/ENSG00000121858/ENSG00000149968/ENSG00000140368/ENSG00000169245/ENSG00000169896 ICAM1/LAMP3/MMP1/IFIH1/TNF/CCL5/MDM2/TNFRSF8/FN1/DLL1/IL7R/MSRA/IL33/NOD2/NFATC1/SERPINE1/RARRES3/PADI2/CDKN1A/VIM/IL32/IL6/CXCL8/MMP2/EGR1/CENPJ/SLC24A3/CPA6/SH2D2A/TNFSF15/BMP4/IL20/IL15/S100A4/GDF15/IL24/TLR2/CTSS/CX3CL1/IKBKE/FLG/TNFSF13B/IL16/IL13/SAA1/TREM1/CCR9/S1PR1/HRH4/TNFSF10/MMP3/PSTPIP1/CXCL10/ITGAM 3383/27074/4312/64135/7124/6352/4193/943/2335/28514/3575/4482/90865/64127/4772/5054/5920/11240/1026/7431/9235/3569/3576/4313/1958/55835/57419/57094/9047/9966/652/50604/3600/6275/9518/11009/7097/1520/6376/9641/2312/10673/3603/3596/6288/54210/10803/1901/59340/8743/4314/9051/3627/3684 54 32 ENSG00000090339/ENSG00000078081/ENSG00000115267/ENSG00000232810/ENSG00000271503/ENSG00000120949/ENSG00000198719/ENSG00000168685/ENSG00000167207/ENSG00000131196/ENSG00000133321/ENSG00000117115/ENSG00000008517/ENSG00000136244/ENSG00000169429/ENSG00000120738/ENSG00000151849/ENSG00000181634/ENSG00000125378/ENSG00000162891/ENSG00000164136/ENSG00000162892/ENSG00000137462/ENSG00000163131/ENSG00000006210/ENSG00000263528/ENSG00000143631/ENSG00000172349/ENSG00000173432/ENSG00000173585/ENSG00000121858/ENSG00000169245 22 ENSG00000196611/ENSG00000135679/ENSG00000115414/ENSG00000175806/ENSG00000137033/ENSG00000106366/ENSG00000124762/ENSG00000026025/ENSG00000087245/ENSG00000185052/ENSG00000165078/ENSG00000027869/ENSG00000196154/ENSG00000130513/ENSG00000102524/ENSG00000169194/ENSG00000124731/ENSG00000170989/ENSG00000134489/ENSG00000149968/ENSG00000140368/ENSG00000169896 DOID:438 autoimmune disease of the nervous system 10/507 37/6464 0.000404161181295582 0.00947823157425445 ENSG00000232810/ENSG00000100097/ENSG00000175920/ENSG00000136244/ENSG00000087245/ENSG00000125730/ENSG00000131095/ENSG00000102524/ENSG00000108556/ENSG00000169245 TNF/LGALS1/DOK7/IL6/MMP2/C3/GFAP/TNFSF13B/CHRNE/CXCL10 7124/3956/285489/3569/4313/718/2670/10673/1145/3627 10 7 ENSG00000232810/ENSG00000175920/ENSG00000136244/ENSG00000125730/ENSG00000131095/ENSG00000108556/ENSG00000169245 3 ENSG00000100097/ENSG00000087245/ENSG00000102524 DOID:850 lung disease 49/507 389/6464 0.000511874652703709 0.01143671990566 ENSG00000090339/ENSG00000103811/ENSG00000196611/ENSG00000115267/ENSG00000232810/ENSG00000271503/ENSG00000120949/ENSG00000125347/ENSG00000122691/ENSG00000087088/ENSG00000145147/ENSG00000175806/ENSG00000167207/ENSG00000106366/ENSG00000119630/ENSG00000055332/ENSG00000115415/ENSG00000169248/ENSG00000149948/ENSG00000176697/ENSG00000095752/ENSG00000189143/ENSG00000166949/ENSG00000178573/ENSG00000151882/ENSG00000136244/ENSG00000169429/ENSG00000087245/ENSG00000165949/ENSG00000140279/ENSG00000156804/ENSG00000167972/ENSG00000137462/ENSG00000108576/ENSG00000163131/ENSG00000006210/ENSG00000172349/ENSG00000169194/ENSG00000163464/ENSG00000124731/ENSG00000173585/ENSG00000149968/ENSG00000065989/ENSG00000128271/ENSG00000169245/ENSG00000146674/ENSG00000169896/ENSG00000105255/ENSG00000130234 ICAM1/CTSH/MMP1/IFIH1/TNF/CCL5/TNFRSF8/IRF1/TWIST1/BAX/SLIT2/MSRA/NOD2/SERPINE1/PGF/EIF2AK2/STAT1/CXCL11/HMGA2/BDNF/IL11/CLDN4/SMAD3/MAF/CCL28/IL6/CXCL8/MMP2/IFI27/DUOX2/FBXO32/ABCA3/TLR2/SLC6A4/CTSS/CX3CL1/IL16/IL13/CXCR1/TREM1/CCR9/MMP3/PDE4A/ADORA2A/CXCL10/IGFBP3/ITGAM/FSD1/ACE2 3383/1512/4312/64135/7124/6352/943/3659/7291/581/9353/4482/64127/5054/5228/5610/6772/6373/8091/627/3589/1364/4088/4094/56477/3569/3576/4313/3429/50506/114907/21/7097/6532/1520/6376/3603/3596/3577/54210/10803/4314/5141/135/3627/3486/3684/79187/59272 49 30 ENSG00000090339/ENSG00000103811/ENSG00000115267/ENSG00000232810/ENSG00000271503/ENSG00000120949/ENSG00000125347/ENSG00000145147/ENSG00000167207/ENSG00000055332/ENSG00000115415/ENSG00000169248/ENSG00000189143/ENSG00000166949/ENSG00000151882/ENSG00000136244/ENSG00000169429/ENSG00000140279/ENSG00000156804/ENSG00000167972/ENSG00000137462/ENSG00000163131/ENSG00000006210/ENSG00000172349/ENSG00000173585/ENSG00000065989/ENSG00000128271/ENSG00000169245/ENSG00000146674/ENSG00000130234 19 ENSG00000196611/ENSG00000122691/ENSG00000087088/ENSG00000175806/ENSG00000106366/ENSG00000119630/ENSG00000149948/ENSG00000176697/ENSG00000095752/ENSG00000178573/ENSG00000087245/ENSG00000165949/ENSG00000108576/ENSG00000169194/ENSG00000163464/ENSG00000124731/ENSG00000149968/ENSG00000169896/ENSG00000105255 DOID:1091 tooth disease 20/507 115/6464 0.000541667770991625 0.01143671990566 ENSG00000168918/ENSG00000196611/ENSG00000232810/ENSG00000271503/ENSG00000167207/ENSG00000131196/ENSG00000106366/ENSG00000095752/ENSG00000136244/ENSG00000169429/ENSG00000087245/ENSG00000164136/ENSG00000162892/ENSG00000137462/ENSG00000108576/ENSG00000102524/ENSG00000172349/ENSG00000169194/ENSG00000121858/ENSG00000149968 INPP5D/MMP1/TNF/CCL5/NOD2/NFATC1/SERPINE1/IL11/IL6/CXCL8/MMP2/IL15/IL24/TLR2/SLC6A4/TNFSF13B/IL16/IL13/TNFSF10/MMP3 3635/4312/7124/6352/64127/4772/5054/3589/3569/3576/4313/3600/11009/7097/6532/10673/3603/3596/8743/4314 20 11 ENSG00000232810/ENSG00000271503/ENSG00000167207/ENSG00000131196/ENSG00000136244/ENSG00000169429/ENSG00000164136/ENSG00000162892/ENSG00000137462/ENSG00000172349/ENSG00000121858 9 ENSG00000168918/ENSG00000196611/ENSG00000106366/ENSG00000095752/ENSG00000087245/ENSG00000108576/ENSG00000102524/ENSG00000169194/ENSG00000149968 DOID:4798 aggressive systemic mastocytosis 7/507 20/6464 0.000550598619942364 0.01143671990566 ENSG00000271503/ENSG00000176697/ENSG00000136244/ENSG00000169429/ENSG00000087245/ENSG00000169194/ENSG00000163464 CCL5/BDNF/IL6/CXCL8/MMP2/IL13/CXCR1 6352/627/3569/3576/4313/3596/3577 7 3 ENSG00000271503/ENSG00000136244/ENSG00000169429 4 ENSG00000176697/ENSG00000087245/ENSG00000169194/ENSG00000163464 DOID:9471 meningitis 7/507 20/6464 0.000550598619942364 0.01143671990566 ENSG00000090339/ENSG00000169429/ENSG00000087245/ENSG00000137462/ENSG00000102524/ENSG00000121858/ENSG00000117228 ICAM1/CXCL8/MMP2/TLR2/TNFSF13B/TNFSF10/GBP1 3383/3576/4313/7097/10673/8743/2633 7 5 ENSG00000090339/ENSG00000169429/ENSG00000137462/ENSG00000121858/ENSG00000117228 2 ENSG00000087245/ENSG00000102524 DOID:437 myasthenia gravis 8/507 26/6464 0.000596100309364701 0.0117125655380578 ENSG00000232810/ENSG00000100097/ENSG00000175920/ENSG00000136244/ENSG00000125730/ENSG00000102524/ENSG00000108556/ENSG00000169245 TNF/LGALS1/DOK7/IL6/C3/TNFSF13B/CHRNE/CXCL10 7124/3956/285489/3569/718/10673/1145/3627 8 6 ENSG00000232810/ENSG00000175920/ENSG00000136244/ENSG00000125730/ENSG00000108556/ENSG00000169245 2 ENSG00000100097/ENSG00000102524 DOID:439 neuromuscular junction disease 8/507 26/6464 0.000596100309364701 0.0117125655380578 ENSG00000232810/ENSG00000100097/ENSG00000175920/ENSG00000136244/ENSG00000125730/ENSG00000102524/ENSG00000108556/ENSG00000169245 TNF/LGALS1/DOK7/IL6/C3/TNFSF13B/CHRNE/CXCL10 7124/3956/285489/3569/718/10673/1145/3627 8 6 ENSG00000232810/ENSG00000175920/ENSG00000136244/ENSG00000125730/ENSG00000108556/ENSG00000169245 2 ENSG00000100097/ENSG00000102524 DOID:9007 sudden infant death syndrome 6/507 15/6464 0.000612576783950073 0.0117195611034659 ENSG00000198626/ENSG00000136244/ENSG00000213523/ENSG00000108576/ENSG00000117013/ENSG00000123700 RYR2/IL6/SRA1/SLC6A4/KCNQ4/KCNJ2 6262/3569/10011/6532/9132/3759 6 4 ENSG00000198626/ENSG00000136244/ENSG00000117013/ENSG00000123700 2 ENSG00000213523/ENSG00000108576 DOID:0060072 benign neoplasm 56/507 469/6464 0.000788873844756207 0.0147054175676349 ENSG00000049130/ENSG00000106484/ENSG00000077942/ENSG00000166670/ENSG00000078018/ENSG00000196611/ENSG00000168477/ENSG00000232810/ENSG00000087494/ENSG00000135679/ENSG00000196730/ENSG00000122691/ENSG00000087088/ENSG00000136205/ENSG00000106366/ENSG00000183734/ENSG00000119888/ENSG00000100097/ENSG00000023445/ENSG00000124762/ENSG00000149948/ENSG00000069482/ENSG00000176697/ENSG00000163083/ENSG00000112964/ENSG00000166949/ENSG00000163347/ENSG00000038427/ENSG00000136244/ENSG00000169429/ENSG00000087245/ENSG00000076706/ENSG00000120738/ENSG00000073111/ENSG00000197956/ENSG00000181885/ENSG00000125378/ENSG00000091129/ENSG00000196154/ENSG00000211445/ENSG00000012048/ENSG00000130513/ENSG00000128342/ENSG00000163131/ENSG00000131095/ENSG00000162366/ENSG00000173267/ENSG00000165887/ENSG00000173432/ENSG00000121858/ENSG00000149968/ENSG00000149295/ENSG00000196584/ENSG00000146674/ENSG00000105255/ENSG00000163132 KITLG/MEST/FBLN1/MMP10/MAP2/MMP1/TNXB/TNF/PTHLH/MDM2/DAPK1/TWIST1/BAX/TNS3/SERPINE1/ASCL2/EPCAM/LGALS1/BIRC3/CDKN1A/HMGA2/GAL/BDNF/INHBB/GHR/SMAD3/CLDN1/VCAN/IL6/CXCL8/MMP2/MCAM/EGR1/MCM2/S100A6/CLDN7/BMP4/NRCAM/S100A4/GPX3/BRCA1/GDF15/LIF/CTSS/GFAP/PDZK1IP1/SNCG/ANKRD2/SAA1/TNFSF10/MMP3/DRD2/XRCC2/IGFBP3/FSD1/MSX1 4254/4232/2192/4319/4133/4312/7148/7124/5744/4193/1612/7291/581/64759/5054/430/4072/3956/330/1026/8091/51083/627/3625/2690/4088/9076/1462/3569/3576/4313/4162/1958/4171/6277/1366/652/4897/6275/2878/672/9518/3976/1520/2670/10158/6623/26287/6288/8743/4314/1813/7516/3486/79187/4487 56 30 ENSG00000106484/ENSG00000077942/ENSG00000078018/ENSG00000168477/ENSG00000232810/ENSG00000136205/ENSG00000183734/ENSG00000119888/ENSG00000023445/ENSG00000069482/ENSG00000166949/ENSG00000163347/ENSG00000136244/ENSG00000169429/ENSG00000076706/ENSG00000120738/ENSG00000073111/ENSG00000181885/ENSG00000125378/ENSG00000211445/ENSG00000012048/ENSG00000163131/ENSG00000131095/ENSG00000162366/ENSG00000173267/ENSG00000165887/ENSG00000173432/ENSG00000121858/ENSG00000196584/ENSG00000146674 26 ENSG00000049130/ENSG00000166670/ENSG00000196611/ENSG00000087494/ENSG00000135679/ENSG00000196730/ENSG00000122691/ENSG00000087088/ENSG00000106366/ENSG00000100097/ENSG00000124762/ENSG00000149948/ENSG00000176697/ENSG00000163083/ENSG00000112964/ENSG00000038427/ENSG00000087245/ENSG00000197956/ENSG00000091129/ENSG00000196154/ENSG00000130513/ENSG00000128342/ENSG00000149968/ENSG00000149295/ENSG00000105255/ENSG00000163132 DOID:2320 obstructive lung disease 33/507 238/6464 0.000839377513244552 0.0152556863032197 ENSG00000090339/ENSG00000196611/ENSG00000232810/ENSG00000271503/ENSG00000125347/ENSG00000087088/ENSG00000167207/ENSG00000106366/ENSG00000055332/ENSG00000115415/ENSG00000169248/ENSG00000176697/ENSG00000166949/ENSG00000178573/ENSG00000151882/ENSG00000136244/ENSG00000169429/ENSG00000087245/ENSG00000140279/ENSG00000156804/ENSG00000137462/ENSG00000108576/ENSG00000163131/ENSG00000006210/ENSG00000172349/ENSG00000169194/ENSG00000124731/ENSG00000173585/ENSG00000149968/ENSG00000065989/ENSG00000128271/ENSG00000169245/ENSG00000169896 ICAM1/MMP1/TNF/CCL5/IRF1/BAX/NOD2/SERPINE1/EIF2AK2/STAT1/CXCL11/BDNF/SMAD3/MAF/CCL28/IL6/CXCL8/MMP2/DUOX2/FBXO32/TLR2/SLC6A4/CTSS/CX3CL1/IL16/IL13/TREM1/CCR9/MMP3/PDE4A/ADORA2A/CXCL10/ITGAM 3383/4312/7124/6352/3659/581/64127/5054/5610/6772/6373/627/4088/4094/56477/3569/3576/4313/50506/114907/7097/6532/1520/6376/3603/3596/54210/10803/4314/5141/135/3627/3684 33 22 ENSG00000090339/ENSG00000232810/ENSG00000271503/ENSG00000125347/ENSG00000167207/ENSG00000055332/ENSG00000115415/ENSG00000169248/ENSG00000166949/ENSG00000151882/ENSG00000136244/ENSG00000169429/ENSG00000140279/ENSG00000156804/ENSG00000137462/ENSG00000163131/ENSG00000006210/ENSG00000172349/ENSG00000173585/ENSG00000065989/ENSG00000128271/ENSG00000169245 11 ENSG00000196611/ENSG00000087088/ENSG00000106366/ENSG00000176697/ENSG00000178573/ENSG00000087245/ENSG00000108576/ENSG00000169194/ENSG00000124731/ENSG00000149968/ENSG00000169896 DOID:2055 post-traumatic stress disorder 5/507 11/6464 0.000902866831036911 0.0156281949086627 ENSG00000176697/ENSG00000136244/ENSG00000169429/ENSG00000108576/ENSG00000149295 BDNF/IL6/CXCL8/SLC6A4/DRD2 627/3569/3576/6532/1813 5 2 ENSG00000136244/ENSG00000169429 3 ENSG00000176697/ENSG00000108576/ENSG00000149295 DOID:2945 severe acute respiratory syndrome 5/507 11/6464 0.000902866831036911 0.0156281949086627 ENSG00000271503/ENSG00000136244/ENSG00000157601/ENSG00000169245/ENSG00000130234 CCL5/IL6/MX1/CXCL10/ACE2 6352/3569/4599/3627/59272 5 5 ENSG00000271503/ENSG00000136244/ENSG00000157601/ENSG00000169245/ENSG00000130234 0 DOID:633 myositis 13/507 63/6464 0.00099437740025404 0.0168119155810392 ENSG00000115267/ENSG00000232810/ENSG00000176697/ENSG00000136244/ENSG00000169429/ENSG00000087245/ENSG00000164136/ENSG00000137462/ENSG00000108576/ENSG00000166313/ENSG00000146674/ENSG00000169896/ENSG00000151623 IFIH1/TNF/BDNF/IL6/CXCL8/MMP2/IL15/TLR2/SLC6A4/APBB1/IGFBP3/ITGAM/NR3C2 64135/7124/627/3569/3576/4313/3600/7097/6532/322/3486/3684/4306 13 8 ENSG00000115267/ENSG00000232810/ENSG00000136244/ENSG00000169429/ENSG00000164136/ENSG00000137462/ENSG00000146674/ENSG00000151623 5 ENSG00000176697/ENSG00000087245/ENSG00000108576/ENSG00000166313/ENSG00000169896 DOID:403 mouth disease 22/507 139/6464 0.00109796289021441 0.0181413413905881 ENSG00000168918/ENSG00000196611/ENSG00000232810/ENSG00000271503/ENSG00000167207/ENSG00000131196/ENSG00000106366/ENSG00000095752/ENSG00000008517/ENSG00000136244/ENSG00000169429/ENSG00000087245/ENSG00000164136/ENSG00000162892/ENSG00000137462/ENSG00000108576/ENSG00000263528/ENSG00000102524/ENSG00000172349/ENSG00000169194/ENSG00000121858/ENSG00000149968 INPP5D/MMP1/TNF/CCL5/NOD2/NFATC1/SERPINE1/IL11/IL32/IL6/CXCL8/MMP2/IL15/IL24/TLR2/SLC6A4/IKBKE/TNFSF13B/IL16/IL13/TNFSF10/MMP3 3635/4312/7124/6352/64127/4772/5054/3589/9235/3569/3576/4313/3600/11009/7097/6532/9641/10673/3603/3596/8743/4314 22 13 ENSG00000232810/ENSG00000271503/ENSG00000167207/ENSG00000131196/ENSG00000008517/ENSG00000136244/ENSG00000169429/ENSG00000164136/ENSG00000162892/ENSG00000137462/ENSG00000263528/ENSG00000172349/ENSG00000121858 9 ENSG00000168918/ENSG00000196611/ENSG00000106366/ENSG00000095752/ENSG00000087245/ENSG00000108576/ENSG00000102524/ENSG00000169194/ENSG00000149968 DOID:74 hematopoietic system disease 46/507 372/6464 0.00113071637150441 0.0182673511574156 ENSG00000049130/ENSG00000090339/ENSG00000166126/ENSG00000139618/ENSG00000232810/ENSG00000271503/ENSG00000120949/ENSG00000198719/ENSG00000087088/ENSG00000167207/ENSG00000106366/ENSG00000243649/ENSG00000023445/ENSG00000172115/ENSG00000055332/ENSG00000124762/ENSG00000072274/ENSG00000149948/ENSG00000176697/ENSG00000095752/ENSG00000126561/ENSG00000136244/ENSG00000169429/ENSG00000087245/ENSG00000140525/ENSG00000120738/ENSG00000125730/ENSG00000241635/ENSG00000164136/ENSG00000197506/ENSG00000158578/ENSG00000104870/ENSG00000137462/ENSG00000197299/ENSG00000006210/ENSG00000136492/ENSG00000144554/ENSG00000102524/ENSG00000169194/ENSG00000163464/ENSG00000160957/ENSG00000121858/ENSG00000169245/ENSG00000146674/ENSG00000169896/ENSG00000181544 KITLG/ICAM1/AMN/BRCA2/TNF/CCL5/TNFRSF8/DLL1/BAX/NOD2/SERPINE1/CFB/BIRC3/CYCS/EIF2AK2/CDKN1A/TFRC/HMGA2/BDNF/IL11/STAT5A/IL6/CXCL8/MMP2/FANCI/EGR1/C3/UGT1A1/IL15/SLC28A3/ALAS2/FCGRT/TLR2/BLM/CX3CL1/BRIP1/FANCD2/TNFSF13B/IL13/CXCR1/RECQL4/TNFSF10/CXCL10/IGFBP3/ITGAM/FANCB 4254/3383/81693/675/7124/6352/943/28514/581/64127/5054/629/330/54205/5610/1026/7037/8091/627/3589/6776/3569/3576/4313/55215/1958/718/54658/3600/64078/212/2217/7097/641/6376/83990/2177/10673/3596/3577/9401/8743/3627/3486/3684/2187 46 33 ENSG00000090339/ENSG00000166126/ENSG00000139618/ENSG00000232810/ENSG00000271503/ENSG00000120949/ENSG00000198719/ENSG00000167207/ENSG00000243649/ENSG00000023445/ENSG00000055332/ENSG00000072274/ENSG00000126561/ENSG00000136244/ENSG00000169429/ENSG00000140525/ENSG00000120738/ENSG00000125730/ENSG00000241635/ENSG00000164136/ENSG00000197506/ENSG00000158578/ENSG00000104870/ENSG00000137462/ENSG00000197299/ENSG00000006210/ENSG00000136492/ENSG00000144554/ENSG00000160957/ENSG00000121858/ENSG00000169245/ENSG00000146674/ENSG00000181544 13 ENSG00000049130/ENSG00000087088/ENSG00000106366/ENSG00000172115/ENSG00000124762/ENSG00000149948/ENSG00000176697/ENSG00000095752/ENSG00000087245/ENSG00000102524/ENSG00000169194/ENSG00000163464/ENSG00000169896 DOID:3310 atopic dermatitis 18/507 105/6464 0.00120393223208925 0.0190273637549758 ENSG00000049130/ENSG00000232810/ENSG00000271503/ENSG00000168685/ENSG00000124762/ENSG00000176697/ENSG00000008517/ENSG00000166949/ENSG00000151882/ENSG00000164136/ENSG00000137462/ENSG00000108576/ENSG00000006210/ENSG00000143631/ENSG00000172349/ENSG00000169194/ENSG00000134489/ENSG00000169245 KITLG/TNF/CCL5/IL7R/CDKN1A/BDNF/IL32/SMAD3/CCL28/IL15/TLR2/SLC6A4/CX3CL1/FLG/IL16/IL13/HRH4/CXCL10 4254/7124/6352/3575/1026/627/9235/4088/56477/3600/7097/6532/6376/2312/3603/3596/59340/3627 18 12 ENSG00000232810/ENSG00000271503/ENSG00000168685/ENSG00000008517/ENSG00000166949/ENSG00000151882/ENSG00000164136/ENSG00000137462/ENSG00000006210/ENSG00000143631/ENSG00000172349/ENSG00000169245 6 ENSG00000049130/ENSG00000124762/ENSG00000176697/ENSG00000108576/ENSG00000169194/ENSG00000134489 DOID:631 fibromyalgia 6/507 17/6464 0.00132255964958793 0.0204574652180941 ENSG00000176697/ENSG00000169429/ENSG00000108576/ENSG00000146674/ENSG00000169896/ENSG00000151623 BDNF/CXCL8/SLC6A4/IGFBP3/ITGAM/NR3C2 627/3576/6532/3486/3684/4306 6 3 ENSG00000169429/ENSG00000146674/ENSG00000151623 3 ENSG00000176697/ENSG00000108576/ENSG00000169896 DOID:552 pneumonia 15/507 82/6464 0.00154795973299597 0.0234451401226682 ENSG00000196611/ENSG00000232810/ENSG00000120949/ENSG00000167207/ENSG00000106366/ENSG00000176697/ENSG00000095752/ENSG00000136244/ENSG00000169429/ENSG00000087245/ENSG00000167972/ENSG00000169194/ENSG00000124731/ENSG00000146674/ENSG00000105255 MMP1/TNF/TNFRSF8/NOD2/SERPINE1/BDNF/IL11/IL6/CXCL8/MMP2/ABCA3/IL13/TREM1/IGFBP3/FSD1 4312/7124/943/64127/5054/627/3589/3569/3576/4313/21/3596/54210/3486/79187 15 7 ENSG00000232810/ENSG00000120949/ENSG00000167207/ENSG00000136244/ENSG00000169429/ENSG00000167972/ENSG00000146674 8 ENSG00000196611/ENSG00000106366/ENSG00000176697/ENSG00000095752/ENSG00000087245/ENSG00000169194/ENSG00000124731/ENSG00000105255 DOID:0060085 organ system benign neoplasm 30/507 218/6464 0.00161355213077729 0.0239398448790835 ENSG00000049130/ENSG00000077942/ENSG00000166670/ENSG00000078018/ENSG00000168477/ENSG00000135679/ENSG00000087088/ENSG00000106366/ENSG00000183734/ENSG00000119888/ENSG00000124762/ENSG00000149948/ENSG00000176697/ENSG00000112964/ENSG00000038427/ENSG00000136244/ENSG00000087245/ENSG00000120738/ENSG00000073111/ENSG00000197956/ENSG00000181885/ENSG00000125378/ENSG00000012048/ENSG00000128342/ENSG00000131095/ENSG00000165887/ENSG00000173432/ENSG00000149295/ENSG00000146674/ENSG00000105255 KITLG/FBLN1/MMP10/MAP2/TNXB/MDM2/BAX/SERPINE1/ASCL2/EPCAM/CDKN1A/HMGA2/BDNF/GHR/VCAN/IL6/MMP2/EGR1/MCM2/S100A6/CLDN7/BMP4/BRCA1/LIF/GFAP/ANKRD2/SAA1/DRD2/IGFBP3/FSD1 4254/2192/4319/4133/7148/4193/581/5054/430/4072/1026/8091/627/2690/1462/3569/4313/1958/4171/6277/1366/652/672/3976/2670/26287/6288/1813/3486/79187 30 15 ENSG00000077942/ENSG00000078018/ENSG00000168477/ENSG00000183734/ENSG00000119888/ENSG00000136244/ENSG00000120738/ENSG00000073111/ENSG00000181885/ENSG00000125378/ENSG00000012048/ENSG00000131095/ENSG00000165887/ENSG00000173432/ENSG00000146674 15 ENSG00000049130/ENSG00000166670/ENSG00000135679/ENSG00000087088/ENSG00000106366/ENSG00000124762/ENSG00000149948/ENSG00000176697/ENSG00000112964/ENSG00000038427/ENSG00000087245/ENSG00000197956/ENSG00000128342/ENSG00000149295/ENSG00000105255 DOID:5082 liver cirrhosis 25/507 171/6464 0.00166793386502906 0.024191050063153 ENSG00000090339/ENSG00000185507/ENSG00000232810/ENSG00000135679/ENSG00000120949/ENSG00000115414/ENSG00000087088/ENSG00000168685/ENSG00000167207/ENSG00000119630/ENSG00000172500/ENSG00000124762/ENSG00000136244/ENSG00000169429/ENSG00000073111/ENSG00000244122/ENSG00000174469/ENSG00000025708/ENSG00000132561/ENSG00000137462/ENSG00000102524/ENSG00000121858/ENSG00000149968/ENSG00000169245/ENSG00000146674 ICAM1/IRF7/TNF/MDM2/TNFRSF8/FN1/BAX/IL7R/NOD2/PGF/FIBP/CDKN1A/IL6/CXCL8/MCM2/UGT1A7/CNTNAP2/TYMP/MATN2/TLR2/TNFSF13B/TNFSF10/MMP3/CXCL10/IGFBP3 3383/3665/7124/4193/943/2335/581/3575/64127/5228/9158/1026/3569/3576/4171/54577/26047/1890/4147/7097/10673/8743/4314/3627/3486 25 16 ENSG00000090339/ENSG00000185507/ENSG00000232810/ENSG00000120949/ENSG00000168685/ENSG00000167207/ENSG00000136244/ENSG00000169429/ENSG00000073111/ENSG00000244122/ENSG00000025708/ENSG00000132561/ENSG00000137462/ENSG00000121858/ENSG00000169245/ENSG00000146674 9 ENSG00000135679/ENSG00000115414/ENSG00000087088/ENSG00000119630/ENSG00000172500/ENSG00000124762/ENSG00000174469/ENSG00000102524/ENSG00000149968 DOID:1883 hepatitis C 27/507 190/6464 0.00169703377334361 0.024191050063153 ENSG00000090339/ENSG00000187608/ENSG00000232810/ENSG00000271503/ENSG00000107201/ENSG00000135679/ENSG00000120949/ENSG00000125347/ENSG00000134321/ENSG00000172183/ENSG00000055332/ENSG00000115415/ENSG00000089127/ENSG00000124762/ENSG00000169248/ENSG00000026025/ENSG00000163347/ENSG00000178573/ENSG00000136244/ENSG00000169429/ENSG00000073111/ENSG00000197506/ENSG00000157601/ENSG00000137462/ENSG00000173432/ENSG00000121858/ENSG00000169245 ICAM1/ISG15/TNF/CCL5/DDX58/MDM2/TNFRSF8/IRF1/RSAD2/ISG20/EIF2AK2/STAT1/OAS1/CDKN1A/CXCL11/VIM/CLDN1/MAF/IL6/CXCL8/MCM2/SLC28A3/MX1/TLR2/SAA1/TNFSF10/CXCL10 3383/9636/7124/6352/23586/4193/943/3659/91543/3669/5610/6772/4938/1026/6373/7431/9076/4094/3569/3576/4171/64078/4599/7097/6288/8743/3627 27 23 ENSG00000090339/ENSG00000187608/ENSG00000232810/ENSG00000271503/ENSG00000107201/ENSG00000120949/ENSG00000125347/ENSG00000134321/ENSG00000172183/ENSG00000055332/ENSG00000115415/ENSG00000089127/ENSG00000169248/ENSG00000163347/ENSG00000136244/ENSG00000169429/ENSG00000073111/ENSG00000197506/ENSG00000157601/ENSG00000137462/ENSG00000173432/ENSG00000121858/ENSG00000169245 4 ENSG00000135679/ENSG00000124762/ENSG00000026025/ENSG00000178573 DOID:10283 prostate cancer 45/507 371/6464 0.00189544733114383 0.0264998117257993 ENSG00000090339/ENSG00000139618/ENSG00000156113/ENSG00000196611/ENSG00000232810/ENSG00000087494/ENSG00000271503/ENSG00000135679/ENSG00000122691/ENSG00000087088/ENSG00000169891/ENSG00000141753/ENSG00000102996/ENSG00000106366/ENSG00000118971/ENSG00000183479/ENSG00000145088/ENSG00000100097/ENSG00000023445/ENSG00000153162/ENSG00000124762/ENSG00000026025/ENSG00000166949/ENSG00000196139/ENSG00000136244/ENSG00000169429/ENSG00000036672/ENSG00000087245/ENSG00000076706/ENSG00000120738/ENSG00000025708/ENSG00000125378/ENSG00000114200/ENSG00000164136/ENSG00000012048/ENSG00000130513/ENSG00000265972/ENSG00000136492/ENSG00000133101/ENSG00000172349/ENSG00000167653/ENSG00000121858/ENSG00000169245/ENSG00000146674/ENSG00000135424 ICAM1/BRCA2/KCNMA1/MMP1/TNF/PTHLH/CCL5/MDM2/TWIST1/BAX/REPS2/IGFBP4/MMP15/SERPINE1/CCND2/TREX2/EAF2/LGALS1/BIRC3/BMP6/CDKN1A/VIM/SMAD3/AKR1C3/IL6/CXCL8/USP2/MMP2/MCAM/EGR1/TYMP/BMP4/BCHE/IL15/BRCA1/GDF15/TXNIP/BRIP1/CCNA1/IL16/PSCA/TNFSF10/CXCL10/IGFBP3/ITGA7 3383/675/3778/4312/7124/5744/6352/4193/7291/581/9185/3487/4324/5054/894/11219/55840/3956/330/654/1026/7431/4088/8644/3569/3576/9099/4313/4162/1958/1890/652/590/3600/672/9518/10628/83990/8900/3603/8000/8743/3627/3486/3679 45 26 ENSG00000090339/ENSG00000139618/ENSG00000232810/ENSG00000271503/ENSG00000169891/ENSG00000141753/ENSG00000102996/ENSG00000183479/ENSG00000023445/ENSG00000166949/ENSG00000136244/ENSG00000169429/ENSG00000036672/ENSG00000076706/ENSG00000120738/ENSG00000025708/ENSG00000125378/ENSG00000164136/ENSG00000012048/ENSG00000136492/ENSG00000172349/ENSG00000167653/ENSG00000121858/ENSG00000169245/ENSG00000146674/ENSG00000135424 19 ENSG00000156113/ENSG00000196611/ENSG00000087494/ENSG00000135679/ENSG00000122691/ENSG00000087088/ENSG00000106366/ENSG00000118971/ENSG00000145088/ENSG00000100097/ENSG00000153162/ENSG00000124762/ENSG00000026025/ENSG00000196139/ENSG00000087245/ENSG00000114200/ENSG00000130513/ENSG00000265972/ENSG00000133101 DOID:2377 multiple sclerosis 20/507 127/6464 0.00193816427813474 0.0265857628340369 ENSG00000090339/ENSG00000115267/ENSG00000271503/ENSG00000125347/ENSG00000168685/ENSG00000167207/ENSG00000106366/ENSG00000023445/ENSG00000176697/ENSG00000136244/ENSG00000169429/ENSG00000125730/ENSG00000165949/ENSG00000114200/ENSG00000198888/ENSG00000157601/ENSG00000006210/ENSG00000169194/ENSG00000149968/ENSG00000169245 ICAM1/IFIH1/CCL5/IRF1/IL7R/NOD2/SERPINE1/BIRC3/BDNF/IL6/CXCL8/C3/IFI27/BCHE/ND1/MX1/CX3CL1/IL13/MMP3/CXCL10 3383/64135/6352/3659/3575/64127/5054/330/627/3569/3576/718/3429/590/4535/4599/6376/3596/4314/3627 20 13 ENSG00000090339/ENSG00000115267/ENSG00000271503/ENSG00000125347/ENSG00000168685/ENSG00000167207/ENSG00000023445/ENSG00000136244/ENSG00000169429/ENSG00000125730/ENSG00000157601/ENSG00000006210/ENSG00000169245 7 ENSG00000106366/ENSG00000176697/ENSG00000165949/ENSG00000114200/ENSG00000198888/ENSG00000169194/ENSG00000149968 DOID:1100 ovarian disease 10/507 45/6464 0.00209426181429867 0.0268160733525252 ENSG00000049130/ENSG00000196611/ENSG00000163083/ENSG00000126733/ENSG00000178919/ENSG00000169429/ENSG00000087245/ENSG00000101115/ENSG00000204531/ENSG00000183770 KITLG/MMP1/INHBB/DACH2/FOXE1/CXCL8/MMP2/SALL4/POU5F1/FOXL2 4254/4312/3625/117154/2304/3576/4313/57167/5460/668 10 5 ENSG00000178919/ENSG00000169429/ENSG00000101115/ENSG00000204531/ENSG00000183770 5 ENSG00000049130/ENSG00000196611/ENSG00000163083/ENSG00000126733/ENSG00000087245 DOID:2394 ovarian cancer 36/507 281/6464 0.00210200678039861 0.0268160733525252 ENSG00000049130/ENSG00000139618/ENSG00000196611/ENSG00000232810/ENSG00000066923/ENSG00000135679/ENSG00000102317/ENSG00000087088/ENSG00000106366/ENSG00000133321/ENSG00000119888/ENSG00000092969/ENSG00000124762/ENSG00000038427/ENSG00000136244/ENSG00000169429/ENSG00000036672/ENSG00000087245/ENSG00000076706/ENSG00000073111/ENSG00000213523/ENSG00000033327/ENSG00000025708/ENSG00000197956/ENSG00000181885/ENSG00000164136/ENSG00000196154/ENSG00000012048/ENSG00000130513/ENSG00000204531/ENSG00000128342/ENSG00000186153/ENSG00000169194/ENSG00000173267/ENSG00000196584/ENSG00000146674 KITLG/BRCA2/MMP1/TNF/STAG3/MDM2/RBM3/BAX/SERPINE1/RARRES3/EPCAM/TGFB2/CDKN1A/VCAN/IL6/CXCL8/USP2/MMP2/MCAM/MCM2/SRA1/GAB2/TYMP/S100A6/CLDN7/IL15/S100A4/BRCA1/GDF15/POU5F1/LIF/WWOX/IL13/SNCG/XRCC2/IGFBP3 4254/675/4312/7124/10734/4193/5935/581/5054/5920/4072/7042/1026/1462/3569/3576/9099/4313/4162/4171/10011/9846/1890/6277/1366/3600/6275/672/9518/5460/3976/51741/3596/6623/7516/3486 36 20 ENSG00000139618/ENSG00000232810/ENSG00000066923/ENSG00000133321/ENSG00000119888/ENSG00000092969/ENSG00000136244/ENSG00000169429/ENSG00000036672/ENSG00000076706/ENSG00000073111/ENSG00000033327/ENSG00000025708/ENSG00000181885/ENSG00000164136/ENSG00000012048/ENSG00000204531/ENSG00000173267/ENSG00000196584/ENSG00000146674 16 ENSG00000049130/ENSG00000196611/ENSG00000135679/ENSG00000102317/ENSG00000087088/ENSG00000106366/ENSG00000124762/ENSG00000038427/ENSG00000087245/ENSG00000213523/ENSG00000197956/ENSG00000196154/ENSG00000130513/ENSG00000128342/ENSG00000186153/ENSG00000169194 DOID:50 thyroid gland disease 19/507 119/6464 0.0021173690682576 0.0268160733525252 ENSG00000090339/ENSG00000115267/ENSG00000232810/ENSG00000271503/ENSG00000125347/ENSG00000087088/ENSG00000106366/ENSG00000100097/ENSG00000169248/ENSG00000178919/ENSG00000136244/ENSG00000169429/ENSG00000092295/ENSG00000140279/ENSG00000172349/ENSG00000169194/ENSG00000175567/ENSG00000169245/ENSG00000146674 ICAM1/IFIH1/TNF/CCL5/IRF1/BAX/SERPINE1/LGALS1/CXCL11/FOXE1/IL6/CXCL8/TGM1/DUOX2/IL16/IL13/UCP2/CXCL10/IGFBP3 3383/64135/7124/6352/3659/581/5054/3956/6373/2304/3569/3576/7051/50506/3603/3596/7351/3627/3486 19 15 ENSG00000090339/ENSG00000115267/ENSG00000232810/ENSG00000271503/ENSG00000125347/ENSG00000169248/ENSG00000178919/ENSG00000136244/ENSG00000169429/ENSG00000092295/ENSG00000140279/ENSG00000172349/ENSG00000175567/ENSG00000169245/ENSG00000146674 4 ENSG00000087088/ENSG00000106366/ENSG00000100097/ENSG00000169194 DOID:350 mastocytosis 8/507 31/6464 0.00212272863558074 0.0268160733525252 ENSG00000049130/ENSG00000271503/ENSG00000176697/ENSG00000136244/ENSG00000169429/ENSG00000087245/ENSG00000169194/ENSG00000163464 KITLG/CCL5/BDNF/IL6/CXCL8/MMP2/IL13/CXCR1 4254/6352/627/3569/3576/4313/3596/3577 8 3 ENSG00000271503/ENSG00000136244/ENSG00000169429 5 ENSG00000049130/ENSG00000176697/ENSG00000087245/ENSG00000169194/ENSG00000163464 DOID:2355 anemia 27/507 193/6464 0.00213938411890848 0.0268160733525252 ENSG00000049130/ENSG00000090339/ENSG00000166126/ENSG00000139618/ENSG00000232810/ENSG00000271503/ENSG00000087088/ENSG00000243649/ENSG00000055332/ENSG00000124762/ENSG00000072274/ENSG00000136244/ENSG00000169429/ENSG00000140525/ENSG00000120738/ENSG00000125730/ENSG00000241635/ENSG00000164136/ENSG00000197506/ENSG00000158578/ENSG00000197299/ENSG00000006210/ENSG00000136492/ENSG00000144554/ENSG00000121858/ENSG00000146674/ENSG00000181544 KITLG/ICAM1/AMN/BRCA2/TNF/CCL5/BAX/CFB/EIF2AK2/CDKN1A/TFRC/IL6/CXCL8/FANCI/EGR1/C3/UGT1A1/IL15/SLC28A3/ALAS2/BLM/CX3CL1/BRIP1/FANCD2/TNFSF10/IGFBP3/FANCB 4254/3383/81693/675/7124/6352/581/629/5610/1026/7037/3569/3576/55215/1958/718/54658/3600/64078/212/641/6376/83990/2177/8743/3486/2187 27 24 ENSG00000090339/ENSG00000166126/ENSG00000139618/ENSG00000232810/ENSG00000271503/ENSG00000243649/ENSG00000055332/ENSG00000072274/ENSG00000136244/ENSG00000169429/ENSG00000140525/ENSG00000120738/ENSG00000125730/ENSG00000241635/ENSG00000164136/ENSG00000197506/ENSG00000158578/ENSG00000197299/ENSG00000006210/ENSG00000136492/ENSG00000144554/ENSG00000121858/ENSG00000146674/ENSG00000181544 3 ENSG00000049130/ENSG00000087088/ENSG00000124762 DOID:10113 trypanosomiasis 5/507 13/6464 0.00220370116011873 0.0271540803967172 ENSG00000232810/ENSG00000136244/ENSG00000164136/ENSG00000137462/ENSG00000169245 TNF/IL6/IL15/TLR2/CXCL10 7124/3569/3600/7097/3627 5 5 ENSG00000232810/ENSG00000136244/ENSG00000164136/ENSG00000137462/ENSG00000169245 0 DOID:594 panic disorder 7/507 25/6464 0.00241889631307603 0.0285561806327027 ENSG00000116741/ENSG00000069482/ENSG00000176697/ENSG00000108576/ENSG00000125510/ENSG00000128271/ENSG00000149295 RGS2/GAL/BDNF/SLC6A4/OPRL1/ADORA2A/DRD2 5997/51083/627/6532/4987/135/1813 7 3 ENSG00000069482/ENSG00000125510/ENSG00000128271 4 ENSG00000116741/ENSG00000176697/ENSG00000108576/ENSG00000149295 DOID:3083 chronic obstructive pulmonary disease 25/507 176/6464 0.00249992891509743 0.0285561806327027 ENSG00000090339/ENSG00000196611/ENSG00000232810/ENSG00000271503/ENSG00000087088/ENSG00000106366/ENSG00000115415/ENSG00000169248/ENSG00000166949/ENSG00000136244/ENSG00000169429/ENSG00000087245/ENSG00000140279/ENSG00000156804/ENSG00000137462/ENSG00000108576/ENSG00000163131/ENSG00000172349/ENSG00000169194/ENSG00000124731/ENSG00000149968/ENSG00000065989/ENSG00000128271/ENSG00000169245/ENSG00000169896 ICAM1/MMP1/TNF/CCL5/BAX/SERPINE1/STAT1/CXCL11/SMAD3/IL6/CXCL8/MMP2/DUOX2/FBXO32/TLR2/SLC6A4/CTSS/IL16/IL13/TREM1/MMP3/PDE4A/ADORA2A/CXCL10/ITGAM 3383/4312/7124/6352/581/5054/6772/6373/4088/3569/3576/4313/50506/114907/7097/6532/1520/3603/3596/54210/4314/5141/135/3627/3684 25 16 ENSG00000090339/ENSG00000232810/ENSG00000271503/ENSG00000115415/ENSG00000169248/ENSG00000166949/ENSG00000136244/ENSG00000169429/ENSG00000140279/ENSG00000156804/ENSG00000137462/ENSG00000163131/ENSG00000172349/ENSG00000065989/ENSG00000128271/ENSG00000169245 9 ENSG00000196611/ENSG00000087088/ENSG00000106366/ENSG00000087245/ENSG00000108576/ENSG00000169194/ENSG00000124731/ENSG00000149968/ENSG00000169896 DOID:6543 acne 6/507 19/6464 0.00253272938789322 0.0285561806327027 ENSG00000232810/ENSG00000167207/ENSG00000136244/ENSG00000087245/ENSG00000137462/ENSG00000143631 TNF/NOD2/IL6/MMP2/TLR2/FLG 7124/64127/3569/4313/7097/2312 6 5 ENSG00000232810/ENSG00000167207/ENSG00000136244/ENSG00000137462/ENSG00000143631 1 ENSG00000087245 DOID:9098 sebaceous gland disease 6/507 19/6464 0.00253272938789322 0.0285561806327027 ENSG00000232810/ENSG00000167207/ENSG00000136244/ENSG00000087245/ENSG00000137462/ENSG00000143631 TNF/NOD2/IL6/MMP2/TLR2/FLG 7124/64127/3569/4313/7097/2312 6 5 ENSG00000232810/ENSG00000167207/ENSG00000136244/ENSG00000137462/ENSG00000143631 1 ENSG00000087245 DOID:9744 type 1 diabetes mellitus 6/507 19/6464 0.00253272938789322 0.0285561806327027 ENSG00000232810/ENSG00000136244/ENSG00000169429/ENSG00000137462/ENSG00000169194/ENSG00000169245 TNF/IL6/CXCL8/TLR2/IL13/CXCL10 7124/3569/3576/7097/3596/3627 6 5 ENSG00000232810/ENSG00000136244/ENSG00000169429/ENSG00000137462/ENSG00000169245 1 ENSG00000169194 DOID:10763 hypertension 53/507 461/6464 0.0025531660813283 0.0285561806327027 ENSG00000090339/ENSG00000035862/ENSG00000156113/ENSG00000089199/ENSG00000196611/ENSG00000173391/ENSG00000232810/ENSG00000120949/ENSG00000146477/ENSG00000166033/ENSG00000167207/ENSG00000106366/ENSG00000119630/ENSG00000116741/ENSG00000100097/ENSG00000204390/ENSG00000153904/ENSG00000182492/ENSG00000176697/ENSG00000163083/ENSG00000112964/ENSG00000038427/ENSG00000136244/ENSG00000169429/ENSG00000087245/ENSG00000125730/ENSG00000146411/ENSG00000127954/ENSG00000240065/ENSG00000125378/ENSG00000164136/ENSG00000196154/ENSG00000211445/ENSG00000130513/ENSG00000198888/ENSG00000137462/ENSG00000204531/ENSG00000108576/ENSG00000128342/ENSG00000006210/ENSG00000186115/ENSG00000102524/ENSG00000166828/ENSG00000172349/ENSG00000175567/ENSG00000149968/ENSG00000173320/ENSG00000128271/ENSG00000169245/ENSG00000170965/ENSG00000134716/ENSG00000151623/ENSG00000130234 ICAM1/TIMP2/KCNMA1/CHGB/MMP1/OLR1/TNF/TNFRSF8/SLC22A3/HTRA1/NOD2/SERPINE1/PGF/RGS2/LGALS1/HSPA1L/DDAH1/BGN/BDNF/INHBB/GHR/VCAN/IL6/CXCL8/MMP2/C3/SLC2A12/STEAP4/PSMB9/BMP4/IL15/S100A4/GPX3/GDF15/ND1/TLR2/POU5F1/SLC6A4/LIF/CX3CL1/CYP4F2/TNFSF13B/SCNN1G/IL16/UCP2/MMP3/STOX2/ADORA2A/CXCL10/PLAC1/CYP2J2/NR3C2/ACE2 3383/7077/3778/1114/4312/4973/7124/943/6581/5654/64127/5054/5228/5997/3956/3305/23576/633/627/3625/2690/1462/3569/3576/4313/718/154091/79689/5698/652/3600/6275/2878/9518/4535/7097/5460/6532/3976/6376/8529/10673/6340/3603/7351/4314/56977/135/3627/10761/1573/4306/59272 53 29 ENSG00000090339/ENSG00000035862/ENSG00000173391/ENSG00000232810/ENSG00000120949/ENSG00000146477/ENSG00000167207/ENSG00000204390/ENSG00000153904/ENSG00000182492/ENSG00000136244/ENSG00000169429/ENSG00000125730/ENSG00000146411/ENSG00000127954/ENSG00000240065/ENSG00000125378/ENSG00000164136/ENSG00000211445/ENSG00000137462/ENSG00000204531/ENSG00000006210/ENSG00000172349/ENSG00000175567/ENSG00000128271/ENSG00000169245/ENSG00000170965/ENSG00000151623/ENSG00000130234 24 ENSG00000156113/ENSG00000089199/ENSG00000196611/ENSG00000166033/ENSG00000106366/ENSG00000119630/ENSG00000116741/ENSG00000100097/ENSG00000176697/ENSG00000163083/ENSG00000112964/ENSG00000038427/ENSG00000087245/ENSG00000196154/ENSG00000130513/ENSG00000198888/ENSG00000108576/ENSG00000128342/ENSG00000186115/ENSG00000102524/ENSG00000166828/ENSG00000149968/ENSG00000173320/ENSG00000134716 DOID:9500 leukocyte disease 13/507 70/6464 0.00271866128931338 0.0299464660201641 ENSG00000049130/ENSG00000232810/ENSG00000271503/ENSG00000023445/ENSG00000176697/ENSG00000136244/ENSG00000169429/ENSG00000087245/ENSG00000241635/ENSG00000164136/ENSG00000169194/ENSG00000163464/ENSG00000160957 KITLG/TNF/CCL5/BIRC3/BDNF/IL6/CXCL8/MMP2/UGT1A1/IL15/IL13/CXCR1/RECQL4 4254/7124/6352/330/627/3569/3576/4313/54658/3600/3596/3577/9401 13 8 ENSG00000232810/ENSG00000271503/ENSG00000023445/ENSG00000136244/ENSG00000169429/ENSG00000241635/ENSG00000164136/ENSG00000160957 5 ENSG00000049130/ENSG00000176697/ENSG00000087245/ENSG00000169194/ENSG00000163464 DOID:2237 hepatitis 42/507 347/6464 0.00277578642924793 0.0301193542397499 ENSG00000090339/ENSG00000167165/ENSG00000187608/ENSG00000232810/ENSG00000271503/ENSG00000107201/ENSG00000135679/ENSG00000120949/ENSG00000125347/ENSG00000134321/ENSG00000087088/ENSG00000172183/ENSG00000179750/ENSG00000213928/ENSG00000055332/ENSG00000115415/ENSG00000089127/ENSG00000124762/ENSG00000169248/ENSG00000026025/ENSG00000166949/ENSG00000163347/ENSG00000178573/ENSG00000136244/ENSG00000169429/ENSG00000087245/ENSG00000073111/ENSG00000244122/ENSG00000240065/ENSG00000197506/ENSG00000157601/ENSG00000179388/ENSG00000137462/ENSG00000175745/ENSG00000102524/ENSG00000163464/ENSG00000173432/ENSG00000121858/ENSG00000149968/ENSG00000122877/ENSG00000169245/ENSG00000125798 ICAM1/UGT1A6/ISG15/TNF/CCL5/DDX58/MDM2/TNFRSF8/IRF1/RSAD2/BAX/ISG20/APOBEC3B/IRF9/EIF2AK2/STAT1/OAS1/CDKN1A/CXCL11/VIM/SMAD3/CLDN1/MAF/IL6/CXCL8/MMP2/MCM2/UGT1A7/PSMB9/SLC28A3/MX1/EGR3/TLR2/NR2F1/TNFSF13B/CXCR1/SAA1/TNFSF10/MMP3/EGR2/CXCL10/FOXA2 3383/54578/9636/7124/6352/23586/4193/943/3659/91543/581/3669/9582/10379/5610/6772/4938/1026/6373/7431/4088/9076/4094/3569/3576/4313/4171/54577/5698/64078/4599/1960/7097/7025/10673/3577/6288/8743/4314/1959/3627/3170 42 31 ENSG00000090339/ENSG00000167165/ENSG00000187608/ENSG00000232810/ENSG00000271503/ENSG00000107201/ENSG00000120949/ENSG00000125347/ENSG00000134321/ENSG00000172183/ENSG00000179750/ENSG00000213928/ENSG00000055332/ENSG00000115415/ENSG00000089127/ENSG00000169248/ENSG00000166949/ENSG00000163347/ENSG00000136244/ENSG00000169429/ENSG00000073111/ENSG00000244122/ENSG00000240065/ENSG00000197506/ENSG00000157601/ENSG00000179388/ENSG00000137462/ENSG00000173432/ENSG00000121858/ENSG00000122877/ENSG00000169245 11 ENSG00000135679/ENSG00000087088/ENSG00000124762/ENSG00000026025/ENSG00000178573/ENSG00000087245/ENSG00000175745/ENSG00000102524/ENSG00000163464/ENSG00000149968/ENSG00000125798 DOID:3856 male reproductive organ cancer 45/507 380/6464 0.00304255909892894 0.0319449576499311 ENSG00000090339/ENSG00000139618/ENSG00000156113/ENSG00000196611/ENSG00000232810/ENSG00000087494/ENSG00000271503/ENSG00000135679/ENSG00000122691/ENSG00000087088/ENSG00000169891/ENSG00000141753/ENSG00000102996/ENSG00000106366/ENSG00000118971/ENSG00000183479/ENSG00000145088/ENSG00000100097/ENSG00000023445/ENSG00000153162/ENSG00000124762/ENSG00000026025/ENSG00000166949/ENSG00000196139/ENSG00000136244/ENSG00000169429/ENSG00000036672/ENSG00000087245/ENSG00000076706/ENSG00000120738/ENSG00000025708/ENSG00000125378/ENSG00000114200/ENSG00000164136/ENSG00000012048/ENSG00000130513/ENSG00000265972/ENSG00000136492/ENSG00000133101/ENSG00000172349/ENSG00000167653/ENSG00000121858/ENSG00000169245/ENSG00000146674/ENSG00000135424 ICAM1/BRCA2/KCNMA1/MMP1/TNF/PTHLH/CCL5/MDM2/TWIST1/BAX/REPS2/IGFBP4/MMP15/SERPINE1/CCND2/TREX2/EAF2/LGALS1/BIRC3/BMP6/CDKN1A/VIM/SMAD3/AKR1C3/IL6/CXCL8/USP2/MMP2/MCAM/EGR1/TYMP/BMP4/BCHE/IL15/BRCA1/GDF15/TXNIP/BRIP1/CCNA1/IL16/PSCA/TNFSF10/CXCL10/IGFBP3/ITGA7 3383/675/3778/4312/7124/5744/6352/4193/7291/581/9185/3487/4324/5054/894/11219/55840/3956/330/654/1026/7431/4088/8644/3569/3576/9099/4313/4162/1958/1890/652/590/3600/672/9518/10628/83990/8900/3603/8000/8743/3627/3486/3679 45 26 ENSG00000090339/ENSG00000139618/ENSG00000232810/ENSG00000271503/ENSG00000169891/ENSG00000141753/ENSG00000102996/ENSG00000183479/ENSG00000023445/ENSG00000166949/ENSG00000136244/ENSG00000169429/ENSG00000036672/ENSG00000076706/ENSG00000120738/ENSG00000025708/ENSG00000125378/ENSG00000164136/ENSG00000012048/ENSG00000136492/ENSG00000172349/ENSG00000167653/ENSG00000121858/ENSG00000169245/ENSG00000146674/ENSG00000135424 19 ENSG00000156113/ENSG00000196611/ENSG00000087494/ENSG00000135679/ENSG00000122691/ENSG00000087088/ENSG00000106366/ENSG00000118971/ENSG00000145088/ENSG00000100097/ENSG00000153162/ENSG00000124762/ENSG00000026025/ENSG00000196139/ENSG00000087245/ENSG00000114200/ENSG00000130513/ENSG00000265972/ENSG00000133101 DOID:3213 demyelinating disease 20/507 132/6464 0.00309251925347787 0.0319449576499311 ENSG00000090339/ENSG00000115267/ENSG00000271503/ENSG00000125347/ENSG00000168685/ENSG00000167207/ENSG00000106366/ENSG00000023445/ENSG00000176697/ENSG00000136244/ENSG00000169429/ENSG00000125730/ENSG00000165949/ENSG00000114200/ENSG00000198888/ENSG00000157601/ENSG00000006210/ENSG00000169194/ENSG00000149968/ENSG00000169245 ICAM1/IFIH1/CCL5/IRF1/IL7R/NOD2/SERPINE1/BIRC3/BDNF/IL6/CXCL8/C3/IFI27/BCHE/ND1/MX1/CX3CL1/IL13/MMP3/CXCL10 3383/64135/6352/3659/3575/64127/5054/330/627/3569/3576/718/3429/590/4535/4599/6376/3596/4314/3627 20 13 ENSG00000090339/ENSG00000115267/ENSG00000271503/ENSG00000125347/ENSG00000168685/ENSG00000167207/ENSG00000023445/ENSG00000136244/ENSG00000169429/ENSG00000125730/ENSG00000157601/ENSG00000006210/ENSG00000169245 7 ENSG00000106366/ENSG00000176697/ENSG00000165949/ENSG00000114200/ENSG00000198888/ENSG00000169194/ENSG00000149968 DOID:440 neuromuscular disease 12/507 63/6464 0.00314531757048044 0.0319449576499311 ENSG00000232810/ENSG00000196218/ENSG00000100097/ENSG00000175920/ENSG00000277586/ENSG00000136244/ENSG00000087245/ENSG00000125730/ENSG00000102524/ENSG00000108556/ENSG00000169245/ENSG00000149295 TNF/RYR1/LGALS1/DOK7/NEFL/IL6/MMP2/C3/TNFSF13B/CHRNE/CXCL10/DRD2 7124/6261/3956/285489/4747/3569/4313/718/10673/1145/3627/1813 12 7 ENSG00000232810/ENSG00000196218/ENSG00000175920/ENSG00000136244/ENSG00000125730/ENSG00000108556/ENSG00000169245 5 ENSG00000100097/ENSG00000277586/ENSG00000087245/ENSG00000102524/ENSG00000149295 DOID:987 alopecia 9/507 40/6464 0.00316693571179345 0.0319449576499311 ENSG00000090339/ENSG00000136244/ENSG00000131080/ENSG00000128342/ENSG00000136695/ENSG00000143631/ENSG00000102524/ENSG00000172349/ENSG00000151623 ICAM1/IL6/EDA2R/LIF/IL36RN/FLG/TNFSF13B/IL16/NR3C2 3383/3569/60401/3976/26525/2312/10673/3603/4306 9 6 ENSG00000090339/ENSG00000136244/ENSG00000136695/ENSG00000143631/ENSG00000172349/ENSG00000151623 3 ENSG00000131080/ENSG00000128342/ENSG00000102524 DOID:2151 malignant ovarian surface epithelial-stromal neoplasm 33/507 258/6464 0.00326529390813944 0.0319449576499311 ENSG00000139618/ENSG00000196611/ENSG00000232810/ENSG00000066923/ENSG00000135679/ENSG00000102317/ENSG00000087088/ENSG00000106366/ENSG00000133321/ENSG00000119888/ENSG00000092969/ENSG00000124762/ENSG00000038427/ENSG00000136244/ENSG00000169429/ENSG00000036672/ENSG00000087245/ENSG00000076706/ENSG00000073111/ENSG00000213523/ENSG00000033327/ENSG00000025708/ENSG00000197956/ENSG00000181885/ENSG00000196154/ENSG00000012048/ENSG00000130513/ENSG00000204531/ENSG00000128342/ENSG00000186153/ENSG00000173267/ENSG00000196584/ENSG00000146674 BRCA2/MMP1/TNF/STAG3/MDM2/RBM3/BAX/SERPINE1/RARRES3/EPCAM/TGFB2/CDKN1A/VCAN/IL6/CXCL8/USP2/MMP2/MCAM/MCM2/SRA1/GAB2/TYMP/S100A6/CLDN7/S100A4/BRCA1/GDF15/POU5F1/LIF/WWOX/SNCG/XRCC2/IGFBP3 675/4312/7124/10734/4193/5935/581/5054/5920/4072/7042/1026/1462/3569/3576/9099/4313/4162/4171/10011/9846/1890/6277/1366/6275/672/9518/5460/3976/51741/6623/7516/3486 33 19 ENSG00000139618/ENSG00000232810/ENSG00000066923/ENSG00000133321/ENSG00000119888/ENSG00000092969/ENSG00000136244/ENSG00000169429/ENSG00000036672/ENSG00000076706/ENSG00000073111/ENSG00000033327/ENSG00000025708/ENSG00000181885/ENSG00000012048/ENSG00000204531/ENSG00000173267/ENSG00000196584/ENSG00000146674 14 ENSG00000196611/ENSG00000135679/ENSG00000102317/ENSG00000087088/ENSG00000106366/ENSG00000124762/ENSG00000038427/ENSG00000087245/ENSG00000213523/ENSG00000197956/ENSG00000196154/ENSG00000130513/ENSG00000128342/ENSG00000186153 DOID:2152 ovary epithelial cancer 33/507 258/6464 0.00326529390813944 0.0319449576499311 ENSG00000139618/ENSG00000196611/ENSG00000232810/ENSG00000066923/ENSG00000135679/ENSG00000102317/ENSG00000087088/ENSG00000106366/ENSG00000133321/ENSG00000119888/ENSG00000092969/ENSG00000124762/ENSG00000038427/ENSG00000136244/ENSG00000169429/ENSG00000036672/ENSG00000087245/ENSG00000076706/ENSG00000073111/ENSG00000213523/ENSG00000033327/ENSG00000025708/ENSG00000197956/ENSG00000181885/ENSG00000196154/ENSG00000012048/ENSG00000130513/ENSG00000204531/ENSG00000128342/ENSG00000186153/ENSG00000173267/ENSG00000196584/ENSG00000146674 BRCA2/MMP1/TNF/STAG3/MDM2/RBM3/BAX/SERPINE1/RARRES3/EPCAM/TGFB2/CDKN1A/VCAN/IL6/CXCL8/USP2/MMP2/MCAM/MCM2/SRA1/GAB2/TYMP/S100A6/CLDN7/S100A4/BRCA1/GDF15/POU5F1/LIF/WWOX/SNCG/XRCC2/IGFBP3 675/4312/7124/10734/4193/5935/581/5054/5920/4072/7042/1026/1462/3569/3576/9099/4313/4162/4171/10011/9846/1890/6277/1366/6275/672/9518/5460/3976/51741/6623/7516/3486 33 19 ENSG00000139618/ENSG00000232810/ENSG00000066923/ENSG00000133321/ENSG00000119888/ENSG00000092969/ENSG00000136244/ENSG00000169429/ENSG00000036672/ENSG00000076706/ENSG00000073111/ENSG00000033327/ENSG00000025708/ENSG00000181885/ENSG00000012048/ENSG00000204531/ENSG00000173267/ENSG00000196584/ENSG00000146674 14 ENSG00000196611/ENSG00000135679/ENSG00000102317/ENSG00000087088/ENSG00000106366/ENSG00000124762/ENSG00000038427/ENSG00000087245/ENSG00000213523/ENSG00000197956/ENSG00000196154/ENSG00000130513/ENSG00000128342/ENSG00000186153 DOID:4001 ovarian carcinoma 33/507 258/6464 0.00326529390813944 0.0319449576499311 ENSG00000139618/ENSG00000196611/ENSG00000232810/ENSG00000066923/ENSG00000135679/ENSG00000102317/ENSG00000087088/ENSG00000106366/ENSG00000133321/ENSG00000119888/ENSG00000092969/ENSG00000124762/ENSG00000038427/ENSG00000136244/ENSG00000169429/ENSG00000036672/ENSG00000087245/ENSG00000076706/ENSG00000073111/ENSG00000213523/ENSG00000033327/ENSG00000025708/ENSG00000197956/ENSG00000181885/ENSG00000196154/ENSG00000012048/ENSG00000130513/ENSG00000204531/ENSG00000128342/ENSG00000186153/ENSG00000173267/ENSG00000196584/ENSG00000146674 BRCA2/MMP1/TNF/STAG3/MDM2/RBM3/BAX/SERPINE1/RARRES3/EPCAM/TGFB2/CDKN1A/VCAN/IL6/CXCL8/USP2/MMP2/MCAM/MCM2/SRA1/GAB2/TYMP/S100A6/CLDN7/S100A4/BRCA1/GDF15/POU5F1/LIF/WWOX/SNCG/XRCC2/IGFBP3 675/4312/7124/10734/4193/5935/581/5054/5920/4072/7042/1026/1462/3569/3576/9099/4313/4162/4171/10011/9846/1890/6277/1366/6275/672/9518/5460/3976/51741/6623/7516/3486 33 19 ENSG00000139618/ENSG00000232810/ENSG00000066923/ENSG00000133321/ENSG00000119888/ENSG00000092969/ENSG00000136244/ENSG00000169429/ENSG00000036672/ENSG00000076706/ENSG00000073111/ENSG00000033327/ENSG00000025708/ENSG00000181885/ENSG00000012048/ENSG00000204531/ENSG00000173267/ENSG00000196584/ENSG00000146674 14 ENSG00000196611/ENSG00000135679/ENSG00000102317/ENSG00000087088/ENSG00000106366/ENSG00000124762/ENSG00000038427/ENSG00000087245/ENSG00000213523/ENSG00000197956/ENSG00000196154/ENSG00000130513/ENSG00000128342/ENSG00000186153 DOID:2841 asthma 16/507 97/6464 0.00331753703340984 0.0319449576499311 ENSG00000090339/ENSG00000271503/ENSG00000125347/ENSG00000087088/ENSG00000106366/ENSG00000176697/ENSG00000178573/ENSG00000151882/ENSG00000169429/ENSG00000087245/ENSG00000137462/ENSG00000006210/ENSG00000172349/ENSG00000169194/ENSG00000173585/ENSG00000169245 ICAM1/CCL5/IRF1/BAX/SERPINE1/BDNF/MAF/CCL28/CXCL8/MMP2/TLR2/CX3CL1/IL16/IL13/CCR9/CXCL10 3383/6352/3659/581/5054/627/4094/56477/3576/4313/7097/6376/3603/3596/10803/3627 16 10 ENSG00000090339/ENSG00000271503/ENSG00000125347/ENSG00000151882/ENSG00000169429/ENSG00000137462/ENSG00000006210/ENSG00000172349/ENSG00000173585/ENSG00000169245 6 ENSG00000087088/ENSG00000106366/ENSG00000176697/ENSG00000178573/ENSG00000087245/ENSG00000169194 DOID:11963 esophagitis 6/507 20/6464 0.00338221400272929 0.0319449576499311 ENSG00000136244/ENSG00000169429/ENSG00000164136/ENSG00000136695/ENSG00000169194/ENSG00000163464 IL6/CXCL8/IL15/IL36RN/IL13/CXCR1 3569/3576/3600/26525/3596/3577 6 4 ENSG00000136244/ENSG00000169429/ENSG00000164136/ENSG00000136695 2 ENSG00000169194/ENSG00000163464 DOID:2043 hepatitis B 23/507 161/6464 0.00340440328199588 0.0319449576499311 ENSG00000232810/ENSG00000271503/ENSG00000179750/ENSG00000213928/ENSG00000055332/ENSG00000115415/ENSG00000089127/ENSG00000124762/ENSG00000166949/ENSG00000136244/ENSG00000087245/ENSG00000244122/ENSG00000240065/ENSG00000157601/ENSG00000179388/ENSG00000137462/ENSG00000175745/ENSG00000163464/ENSG00000121858/ENSG00000149968/ENSG00000122877/ENSG00000169245/ENSG00000125798 TNF/CCL5/APOBEC3B/IRF9/EIF2AK2/STAT1/OAS1/CDKN1A/SMAD3/IL6/MMP2/UGT1A7/PSMB9/MX1/EGR3/TLR2/NR2F1/CXCR1/TNFSF10/MMP3/EGR2/CXCL10/FOXA2 7124/6352/9582/10379/5610/6772/4938/1026/4088/3569/4313/54577/5698/4599/1960/7097/7025/3577/8743/4314/1959/3627/3170 23 17 ENSG00000232810/ENSG00000271503/ENSG00000179750/ENSG00000213928/ENSG00000055332/ENSG00000115415/ENSG00000089127/ENSG00000166949/ENSG00000136244/ENSG00000244122/ENSG00000240065/ENSG00000157601/ENSG00000179388/ENSG00000137462/ENSG00000121858/ENSG00000122877/ENSG00000169245 6 ENSG00000124762/ENSG00000087245/ENSG00000175745/ENSG00000163464/ENSG00000149968/ENSG00000125798 DOID:10591 pre-eclampsia 29/507 219/6464 0.00343010895699736 0.0319449576499311 ENSG00000090339/ENSG00000196611/ENSG00000173391/ENSG00000232810/ENSG00000120949/ENSG00000146477/ENSG00000166033/ENSG00000167207/ENSG00000106366/ENSG00000119630/ENSG00000100097/ENSG00000153904/ENSG00000182492/ENSG00000163083/ENSG00000038427/ENSG00000136244/ENSG00000169429/ENSG00000087245/ENSG00000164136/ENSG00000211445/ENSG00000130513/ENSG00000137462/ENSG00000128342/ENSG00000102524/ENSG00000172349/ENSG00000173320/ENSG00000128271/ENSG00000169245/ENSG00000170965 ICAM1/MMP1/OLR1/TNF/TNFRSF8/SLC22A3/HTRA1/NOD2/SERPINE1/PGF/LGALS1/DDAH1/BGN/INHBB/VCAN/IL6/CXCL8/MMP2/IL15/GPX3/GDF15/TLR2/LIF/TNFSF13B/IL16/STOX2/ADORA2A/CXCL10/PLAC1 3383/4312/4973/7124/943/6581/5654/64127/5054/5228/3956/23576/633/3625/1462/3569/3576/4313/3600/2878/9518/7097/3976/10673/3603/56977/135/3627/10761 29 17 ENSG00000090339/ENSG00000173391/ENSG00000232810/ENSG00000120949/ENSG00000146477/ENSG00000167207/ENSG00000153904/ENSG00000182492/ENSG00000136244/ENSG00000169429/ENSG00000164136/ENSG00000211445/ENSG00000137462/ENSG00000172349/ENSG00000128271/ENSG00000169245/ENSG00000170965 12 ENSG00000196611/ENSG00000166033/ENSG00000106366/ENSG00000119630/ENSG00000100097/ENSG00000163083/ENSG00000038427/ENSG00000087245/ENSG00000130513/ENSG00000128342/ENSG00000102524/ENSG00000173320 DOID:750 peptic ulcer disease 10/507 48/6464 0.0034713227707628 0.0319449576499311 ENSG00000167165/ENSG00000232810/ENSG00000136244/ENSG00000169429/ENSG00000137462/ENSG00000204531/ENSG00000136695/ENSG00000163464/ENSG00000124731/ENSG00000149968 UGT1A6/TNF/IL6/CXCL8/TLR2/POU5F1/IL36RN/CXCR1/TREM1/MMP3 54578/7124/3569/3576/7097/5460/26525/3577/54210/4314 10 7 ENSG00000167165/ENSG00000232810/ENSG00000136244/ENSG00000169429/ENSG00000137462/ENSG00000204531/ENSG00000136695 3 ENSG00000163464/ENSG00000124731/ENSG00000149968 DOID:10747 lymphoid leukemia 12/507 64/6464 0.00360330319695792 0.0327450178023551 ENSG00000254087/ENSG00000161405/ENSG00000087494/ENSG00000120949/ENSG00000106366/ENSG00000118971/ENSG00000124762/ENSG00000169429/ENSG00000112182/ENSG00000265972/ENSG00000173585/ENSG00000121858 LYN/IKZF3/PTHLH/TNFRSF8/SERPINE1/CCND2/CDKN1A/CXCL8/BACH2/TXNIP/CCR9/TNFSF10 4067/22806/5744/943/5054/894/1026/3576/60468/10628/10803/8743 12 7 ENSG00000254087/ENSG00000161405/ENSG00000120949/ENSG00000169429/ENSG00000112182/ENSG00000173585/ENSG00000121858 5 ENSG00000087494/ENSG00000106366/ENSG00000118971/ENSG00000124762/ENSG00000265972 DOID:349 systemic mastocytosis 7/507 27/6464 0.00389567371207702 0.0349648739343209 ENSG00000271503/ENSG00000176697/ENSG00000136244/ENSG00000169429/ENSG00000087245/ENSG00000169194/ENSG00000163464 CCL5/BDNF/IL6/CXCL8/MMP2/IL13/CXCR1 6352/627/3569/3576/4313/3596/3577 7 3 ENSG00000271503/ENSG00000136244/ENSG00000169429 4 ENSG00000176697/ENSG00000087245/ENSG00000169194/ENSG00000163464 DOID:3480 uveal disease 8/507 34/6464 0.00396566492904342 0.0351590049196899 ENSG00000090339/ENSG00000196611/ENSG00000232810/ENSG00000129038/ENSG00000167207/ENSG00000204390/ENSG00000137462/ENSG00000149968 ICAM1/MMP1/TNF/LOXL1/NOD2/HSPA1L/TLR2/MMP3 3383/4312/7124/4016/64127/3305/7097/4314 8 6 ENSG00000090339/ENSG00000232810/ENSG00000129038/ENSG00000167207/ENSG00000204390/ENSG00000137462 2 ENSG00000196611/ENSG00000149968 DOID:1588 thrombocytopenia 11/507 57/6464 0.00415556153971061 0.0363987137273447 ENSG00000090339/ENSG00000271503/ENSG00000167207/ENSG00000106366/ENSG00000172115/ENSG00000095752/ENSG00000136244/ENSG00000169429/ENSG00000102524/ENSG00000121858/ENSG00000169245 ICAM1/CCL5/NOD2/SERPINE1/CYCS/IL11/IL6/CXCL8/TNFSF13B/TNFSF10/CXCL10 3383/6352/64127/5054/54205/3589/3569/3576/10673/8743/3627 11 7 ENSG00000090339/ENSG00000271503/ENSG00000167207/ENSG00000136244/ENSG00000169429/ENSG00000121858/ENSG00000169245 4 ENSG00000106366/ENSG00000172115/ENSG00000095752/ENSG00000102524 DOID:5100 middle ear disease 6/507 21/6464 0.00442680060855814 0.037862165204962 ENSG00000106366/ENSG00000119630/ENSG00000124762/ENSG00000136244/ENSG00000169429/ENSG00000087245 SERPINE1/PGF/CDKN1A/IL6/CXCL8/MMP2 5054/5228/1026/3569/3576/4313 6 2 ENSG00000136244/ENSG00000169429 4 ENSG00000106366/ENSG00000119630/ENSG00000124762/ENSG00000087245 DOID:9446 cholangitis 6/507 21/6464 0.00442680060855814 0.037862165204962 ENSG00000090339/ENSG00000271503/ENSG00000163347/ENSG00000136244/ENSG00000137462/ENSG00000124731 ICAM1/CCL5/CLDN1/IL6/TLR2/TREM1 3383/6352/9076/3569/7097/54210 6 5 ENSG00000090339/ENSG00000271503/ENSG00000163347/ENSG00000136244/ENSG00000137462 1 ENSG00000124731 DOID:84 osteochondritis dissecans 5/507 15/6464 0.00450784085784907 0.0381069802750729 ENSG00000232810/ENSG00000176697/ENSG00000108576/ENSG00000149968/ENSG00000149295 TNF/BDNF/SLC6A4/MMP3/DRD2 7124/627/6532/4314/1813 5 1 ENSG00000232810 4 ENSG00000176697/ENSG00000108576/ENSG00000149968/ENSG00000149295 DOID:4971 myelofibrosis 9/507 43/6464 0.00529215907559683 0.0432876182542814 ENSG00000254087/ENSG00000232810/ENSG00000115414/ENSG00000153162/ENSG00000149948/ENSG00000169429/ENSG00000076706/ENSG00000164136/ENSG00000163464 LYN/TNF/FN1/BMP6/HMGA2/CXCL8/MCAM/IL15/CXCR1 4067/7124/2335/654/8091/3576/4162/3600/3577 9 5 ENSG00000254087/ENSG00000232810/ENSG00000169429/ENSG00000076706/ENSG00000164136 4 ENSG00000115414/ENSG00000153162/ENSG00000149948/ENSG00000163464 DOID:127 leiomyoma 14/507 84/6464 0.00530987981780473 0.0432876182542814 ENSG00000106484/ENSG00000232810/ENSG00000087494/ENSG00000196730/ENSG00000087088/ENSG00000100097/ENSG00000124762/ENSG00000149948/ENSG00000038427/ENSG00000136244/ENSG00000087245/ENSG00000120738/ENSG00000196154/ENSG00000149295 MEST/TNF/PTHLH/DAPK1/BAX/LGALS1/CDKN1A/HMGA2/VCAN/IL6/MMP2/EGR1/S100A4/DRD2 4232/7124/5744/1612/581/3956/1026/8091/1462/3569/4313/1958/6275/1813 14 4 ENSG00000106484/ENSG00000232810/ENSG00000136244/ENSG00000120738 10 ENSG00000087494/ENSG00000196730/ENSG00000087088/ENSG00000100097/ENSG00000124762/ENSG00000149948/ENSG00000038427/ENSG00000087245/ENSG00000196154/ENSG00000149295 DOID:11400 pyelonephritis 4/507 10/6464 0.00535885232859054 0.0432876182542814 ENSG00000120949/ENSG00000136244/ENSG00000169429/ENSG00000169245 TNFRSF8/IL6/CXCL8/CXCL10 943/3569/3576/3627 4 4 ENSG00000120949/ENSG00000136244/ENSG00000169429/ENSG00000169245 0 DOID:2744 pyelitis 4/507 10/6464 0.00535885232859054 0.0432876182542814 ENSG00000120949/ENSG00000136244/ENSG00000169429/ENSG00000169245 TNFRSF8/IL6/CXCL8/CXCL10 943/3569/3576/3627 4 4 ENSG00000120949/ENSG00000136244/ENSG00000169429/ENSG00000169245 0 DOID:12361 Graves' disease 11/507 59/6464 0.00546720741931912 0.0435694351025676 ENSG00000090339/ENSG00000115267/ENSG00000232810/ENSG00000271503/ENSG00000125347/ENSG00000087088/ENSG00000136244/ENSG00000169429/ENSG00000172349/ENSG00000169194/ENSG00000169245 ICAM1/IFIH1/TNF/CCL5/IRF1/BAX/IL6/CXCL8/IL16/IL13/CXCL10 3383/64135/7124/6352/3659/581/3569/3576/3603/3596/3627 11 9 ENSG00000090339/ENSG00000115267/ENSG00000232810/ENSG00000271503/ENSG00000125347/ENSG00000136244/ENSG00000169429/ENSG00000172349/ENSG00000169245 2 ENSG00000087088/ENSG00000169194 DOID:409 liver disease 55/507 500/6464 0.00551360114090264 0.0435694351025676 ENSG00000090339/ENSG00000167165/ENSG00000185507/ENSG00000187608/ENSG00000232810/ENSG00000271503/ENSG00000107201/ENSG00000135679/ENSG00000120949/ENSG00000125347/ENSG00000115414/ENSG00000134321/ENSG00000087088/ENSG00000168685/ENSG00000167207/ENSG00000106366/ENSG00000119630/ENSG00000172183/ENSG00000179750/ENSG00000172500/ENSG00000213928/ENSG00000055332/ENSG00000115415/ENSG00000089127/ENSG00000124762/ENSG00000169248/ENSG00000026025/ENSG00000112964/ENSG00000166949/ENSG00000163347/ENSG00000178573/ENSG00000136244/ENSG00000169429/ENSG00000087245/ENSG00000073111/ENSG00000244122/ENSG00000174469/ENSG00000167779/ENSG00000025708/ENSG00000132561/ENSG00000240065/ENSG00000197506/ENSG00000157601/ENSG00000179388/ENSG00000137462/ENSG00000175745/ENSG00000102524/ENSG00000163464/ENSG00000173432/ENSG00000121858/ENSG00000149968/ENSG00000122877/ENSG00000169245/ENSG00000146674/ENSG00000125798 ICAM1/UGT1A6/IRF7/ISG15/TNF/CCL5/DDX58/MDM2/TNFRSF8/IRF1/FN1/RSAD2/BAX/IL7R/NOD2/SERPINE1/PGF/ISG20/APOBEC3B/FIBP/IRF9/EIF2AK2/STAT1/OAS1/CDKN1A/CXCL11/VIM/GHR/SMAD3/CLDN1/MAF/IL6/CXCL8/MMP2/MCM2/UGT1A7/CNTNAP2/IGFBP6/TYMP/MATN2/PSMB9/SLC28A3/MX1/EGR3/TLR2/NR2F1/TNFSF13B/CXCR1/SAA1/TNFSF10/MMP3/EGR2/CXCL10/IGFBP3/FOXA2 3383/54578/3665/9636/7124/6352/23586/4193/943/3659/2335/91543/581/3575/64127/5054/5228/3669/9582/9158/10379/5610/6772/4938/1026/6373/7431/2690/4088/9076/4094/3569/3576/4313/4171/54577/26047/3489/1890/4147/5698/64078/4599/1960/7097/7025/10673/3577/6288/8743/4314/1959/3627/3486/3170 55 38 ENSG00000090339/ENSG00000167165/ENSG00000185507/ENSG00000187608/ENSG00000232810/ENSG00000271503/ENSG00000107201/ENSG00000120949/ENSG00000125347/ENSG00000134321/ENSG00000168685/ENSG00000167207/ENSG00000172183/ENSG00000179750/ENSG00000213928/ENSG00000055332/ENSG00000115415/ENSG00000089127/ENSG00000169248/ENSG00000166949/ENSG00000163347/ENSG00000136244/ENSG00000169429/ENSG00000073111/ENSG00000244122/ENSG00000167779/ENSG00000025708/ENSG00000132561/ENSG00000240065/ENSG00000197506/ENSG00000157601/ENSG00000179388/ENSG00000137462/ENSG00000173432/ENSG00000121858/ENSG00000122877/ENSG00000169245/ENSG00000146674 17 ENSG00000135679/ENSG00000115414/ENSG00000087088/ENSG00000106366/ENSG00000119630/ENSG00000172500/ENSG00000124762/ENSG00000026025/ENSG00000112964/ENSG00000178573/ENSG00000087245/ENSG00000174469/ENSG00000175745/ENSG00000102524/ENSG00000163464/ENSG00000149968/ENSG00000125798 DOID:8398 osteoarthritis 22/507 158/6464 0.00564335743003356 0.0441152779745634 ENSG00000035862/ENSG00000196611/ENSG00000232810/ENSG00000049089/ENSG00000271503/ENSG00000166033/ENSG00000106366/ENSG00000137573/ENSG00000026025/ENSG00000112964/ENSG00000166949/ENSG00000178573/ENSG00000136244/ENSG00000169429/ENSG00000087245/ENSG00000123610/ENSG00000125378/ENSG00000163131/ENSG00000163435/ENSG00000263528/ENSG00000149968/ENSG00000169896 TIMP2/MMP1/TNF/COL9A2/CCL5/HTRA1/SERPINE1/SULF1/VIM/GHR/SMAD3/MAF/IL6/CXCL8/MMP2/TNFAIP6/BMP4/CTSS/ELF3/IKBKE/MMP3/ITGAM 7077/4312/7124/1298/6352/5654/5054/23213/7431/2690/4088/4094/3569/3576/4313/7130/652/1520/1999/9641/4314/3684 22 12 ENSG00000035862/ENSG00000232810/ENSG00000049089/ENSG00000271503/ENSG00000166949/ENSG00000136244/ENSG00000169429/ENSG00000123610/ENSG00000125378/ENSG00000163131/ENSG00000163435/ENSG00000263528 10 ENSG00000196611/ENSG00000166033/ENSG00000106366/ENSG00000137573/ENSG00000026025/ENSG00000112964/ENSG00000178573/ENSG00000087245/ENSG00000149968/ENSG00000169896 DOID:13207 proliferative diabetic retinopathy 7/507 29/6464 0.00597141387531142 0.0456970303931727 ENSG00000049130/ENSG00000090339/ENSG00000232810/ENSG00000119630/ENSG00000136244/ENSG00000087245/ENSG00000175567 KITLG/ICAM1/TNF/PGF/IL6/MMP2/UCP2 4254/3383/7124/5228/3569/4313/7351 7 4 ENSG00000090339/ENSG00000232810/ENSG00000136244/ENSG00000175567 3 ENSG00000049130/ENSG00000119630/ENSG00000087245 DOID:1459 hypothyroidism 7/507 29/6464 0.00597141387531142 0.0456970303931727 ENSG00000232810/ENSG00000169248/ENSG00000178919/ENSG00000092295/ENSG00000140279/ENSG00000175567/ENSG00000146674 TNF/CXCL11/FOXE1/TGM1/DUOX2/UCP2/IGFBP3 7124/6373/2304/7051/50506/7351/3486 7 7 ENSG00000232810/ENSG00000169248/ENSG00000178919/ENSG00000092295/ENSG00000140279/ENSG00000175567/ENSG00000146674 0 DOID:10883 herpangina 5/507 16/6464 0.00614059121008671 0.0460227815436396 ENSG00000135679/ENSG00000166949/ENSG00000169429/ENSG00000164136/ENSG00000108576 MDM2/SMAD3/CXCL8/IL15/SLC6A4 4193/4088/3576/3600/6532 5 3 ENSG00000166949/ENSG00000169429/ENSG00000164136 2 ENSG00000135679/ENSG00000108576 DOID:1724 duodenal ulcer 5/507 16/6464 0.00614059121008671 0.0460227815436396 ENSG00000232810/ENSG00000136244/ENSG00000169429/ENSG00000137462/ENSG00000149968 TNF/IL6/CXCL8/TLR2/MMP3 7124/3569/3576/7097/4314 5 4 ENSG00000232810/ENSG00000136244/ENSG00000169429/ENSG00000137462 1 ENSG00000149968