DOID Description GeneRatio BgRatio pvalue padj geneID geneName EntrezID Count Up Up_Gene_names Down Down_Gene_names DOID:8469 influenza 19/268 93/6421 5.81680862622865e-09 3.8565441191896e-06 ENSG00000187608/ENSG00000234745/ENSG00000185507/ENSG00000115415/ENSG00000107201/ENSG00000090339/ENSG00000130303/ENSG00000115267/ENSG00000271503/ENSG00000160710/ENSG00000055332/ENSG00000157601/ENSG00000137752/ENSG00000185885/ENSG00000169429/ENSG00000163661/ENSG00000232810/ENSG00000239713/ENSG00000008517 ISG15/HLA-B/IRF7/STAT1/DDX58/ICAM1/BST2/IFIH1/CCL5/ADAR/EIF2AK2/MX1/CASP1/IFITM1/CXCL8/PTX3/TNF/APOBEC3G/IL32 9636/3106/3665/6772/23586/3383/684/64135/6352/103/5610/4599/834/8519/3576/5806/7124/60489/9235 19 0 19 ENSG00000187608/ENSG00000234745/ENSG00000185507/ENSG00000115415/ENSG00000107201/ENSG00000090339/ENSG00000130303/ENSG00000115267/ENSG00000271503/ENSG00000160710/ENSG00000055332/ENSG00000157601/ENSG00000137752/ENSG00000185885/ENSG00000169429/ENSG00000163661/ENSG00000232810/ENSG00000239713/ENSG00000008517 DOID:526 Human immunodeficiency virus infectious disease 21/268 132/6421 9.43207511472565e-08 3.04095428342701e-05 ENSG00000234745/ENSG00000125347/ENSG00000204525/ENSG00000166710/ENSG00000090339/ENSG00000132274/ENSG00000271503/ENSG00000179750/ENSG00000168685/ENSG00000169248/ENSG00000006210/ENSG00000184371/ENSG00000197249/ENSG00000232810/ENSG00000164136/ENSG00000239713/ENSG00000160255/ENSG00000150782/ENSG00000044574/ENSG00000277586/ENSG00000197299 HLA-B/IRF1/HLA-C/B2M/ICAM1/TRIM22/CCL5/APOBEC3B/IL7R/CXCL11/CX3CL1/CSF1/SERPINA1/TNF/IL15/APOBEC3G/ITGB2/IL18/HSPA5/NEFL/BLM 3106/3659/3107/567/3383/10346/6352/9582/3575/6373/6376/1435/5265/7124/3600/60489/3689/3606/3309/4747/641 21 2 ENSG00000150782/ENSG00000277586 19 ENSG00000234745/ENSG00000125347/ENSG00000204525/ENSG00000166710/ENSG00000090339/ENSG00000132274/ENSG00000271503/ENSG00000179750/ENSG00000168685/ENSG00000169248/ENSG00000006210/ENSG00000184371/ENSG00000197249/ENSG00000232810/ENSG00000164136/ENSG00000239713/ENSG00000160255/ENSG00000044574/ENSG00000197299 DOID:104 bacterial infectious disease 26/268 198/6421 1.51103600470402e-07 3.04095428342701e-05 ENSG00000234745/ENSG00000125347/ENSG00000115415/ENSG00000090339/ENSG00000079385/ENSG00000271503/ENSG00000136244/ENSG00000137752/ENSG00000169248/ENSG00000240065/ENSG00000149131/ENSG00000169429/ENSG00000135899/ENSG00000204264/ENSG00000000971/ENSG00000115009/ENSG00000163661/ENSG00000232810/ENSG00000149968/ENSG00000111674/ENSG00000102962/ENSG00000008517/ENSG00000160255/ENSG00000169403/ENSG00000137462/ENSG00000150782 HLA-B/IRF1/STAT1/ICAM1/CEACAM1/CCL5/IL6/CASP1/CXCL11/PSMB9/SERPING1/CXCL8/SP110/PSMB8/CFH/CCL20/PTX3/TNF/MMP3/ENO2/CCL22/IL32/ITGB2/PTAFR/TLR2/IL18 3106/3659/6772/3383/634/6352/3569/834/6373/5698/710/3576/3431/5696/3075/6364/5806/7124/4314/2026/6367/9235/3689/5724/7097/3606 26 2 ENSG00000149968/ENSG00000150782 24 ENSG00000234745/ENSG00000125347/ENSG00000115415/ENSG00000090339/ENSG00000079385/ENSG00000271503/ENSG00000136244/ENSG00000137752/ENSG00000169248/ENSG00000240065/ENSG00000149131/ENSG00000169429/ENSG00000135899/ENSG00000204264/ENSG00000000971/ENSG00000115009/ENSG00000163661/ENSG00000232810/ENSG00000111674/ENSG00000102962/ENSG00000008517/ENSG00000160255/ENSG00000169403/ENSG00000137462 DOID:9588 encephalitis 12/268 45/6421 1.83466321775385e-07 3.04095428342701e-05 ENSG00000187608/ENSG00000134321/ENSG00000115415/ENSG00000111331/ENSG00000111335/ENSG00000136244/ENSG00000055332/ENSG00000169429/ENSG00000006210/ENSG00000163661/ENSG00000111674/ENSG00000008517 ISG15/RSAD2/STAT1/OAS3/OAS2/IL6/EIF2AK2/CXCL8/CX3CL1/PTX3/ENO2/IL32 9636/91543/6772/4940/4939/3569/5610/3576/6376/5806/2026/9235 12 0 12 ENSG00000187608/ENSG00000134321/ENSG00000115415/ENSG00000111331/ENSG00000111335/ENSG00000136244/ENSG00000055332/ENSG00000169429/ENSG00000006210/ENSG00000163661/ENSG00000111674/ENSG00000008517 DOID:3213 demyelinating disease 19/268 127/6421 1.04764611080255e-06 0.000138917874292418 ENSG00000234745/ENSG00000125347/ENSG00000165949/ENSG00000204525/ENSG00000090339/ENSG00000115267/ENSG00000271503/ENSG00000136244/ENSG00000157601/ENSG00000137752/ENSG00000168685/ENSG00000023445/ENSG00000169429/ENSG00000006210/ENSG00000149968/ENSG00000176697/ENSG00000160255/ENSG00000150782/ENSG00000115232 HLA-B/IRF1/IFI27/HLA-C/ICAM1/IFIH1/CCL5/IL6/MX1/CASP1/IL7R/BIRC3/CXCL8/CX3CL1/MMP3/BDNF/ITGB2/IL18/ITGA4 3106/3659/3429/3107/3383/64135/6352/3569/4599/834/3575/330/3576/6376/4314/627/3689/3606/3676 19 3 ENSG00000149968/ENSG00000176697/ENSG00000150782 16 ENSG00000234745/ENSG00000125347/ENSG00000165949/ENSG00000204525/ENSG00000090339/ENSG00000115267/ENSG00000271503/ENSG00000136244/ENSG00000157601/ENSG00000137752/ENSG00000168685/ENSG00000023445/ENSG00000169429/ENSG00000006210/ENSG00000160255/ENSG00000115232 DOID:2723 dermatitis 19/268 132/6421 1.91139631290387e-06 0.00018599144050513 ENSG00000090339/ENSG00000271503/ENSG00000162892/ENSG00000136244/ENSG00000168685/ENSG00000151882/ENSG00000006210/ENSG00000011201/ENSG00000232810/ENSG00000157873/ENSG00000164136/ENSG00000102962/ENSG00000176697/ENSG00000008517/ENSG00000128342/ENSG00000162891/ENSG00000206073/ENSG00000137462/ENSG00000150782 ICAM1/CCL5/IL24/IL6/IL7R/CCL28/CX3CL1/ANOS1/TNF/TNFRSF14/IL15/CCL22/BDNF/IL32/LIF/IL20/SERPINB4/TLR2/IL18 3383/6352/11009/3569/3575/56477/6376/3730/7124/8764/3600/6367/627/9235/3976/50604/6318/7097/3606 19 2 ENSG00000176697/ENSG00000150782 17 ENSG00000090339/ENSG00000271503/ENSG00000162892/ENSG00000136244/ENSG00000168685/ENSG00000151882/ENSG00000006210/ENSG00000011201/ENSG00000232810/ENSG00000157873/ENSG00000164136/ENSG00000102962/ENSG00000008517/ENSG00000128342/ENSG00000162891/ENSG00000206073/ENSG00000137462 DOID:0050339 commensal bacterial infectious disease 9/268 30/6421 2.22312050088972e-06 0.00018599144050513 ENSG00000115415/ENSG00000090339/ENSG00000136244/ENSG00000149131/ENSG00000169429/ENSG00000000971/ENSG00000102962/ENSG00000160255/ENSG00000169403 STAT1/ICAM1/IL6/SERPING1/CXCL8/CFH/CCL22/ITGB2/PTAFR 6772/3383/3569/710/3576/3075/6367/3689/5724 9 0 9 ENSG00000115415/ENSG00000090339/ENSG00000136244/ENSG00000149131/ENSG00000169429/ENSG00000000971/ENSG00000102962/ENSG00000160255/ENSG00000169403 DOID:2377 multiple sclerosis 18/268 122/6421 2.49593953953203e-06 0.00018599144050513 ENSG00000234745/ENSG00000125347/ENSG00000165949/ENSG00000204525/ENSG00000090339/ENSG00000115267/ENSG00000271503/ENSG00000136244/ENSG00000157601/ENSG00000137752/ENSG00000168685/ENSG00000023445/ENSG00000169429/ENSG00000006210/ENSG00000149968/ENSG00000176697/ENSG00000150782/ENSG00000115232 HLA-B/IRF1/IFI27/HLA-C/ICAM1/IFIH1/CCL5/IL6/MX1/CASP1/IL7R/BIRC3/CXCL8/CX3CL1/MMP3/BDNF/IL18/ITGA4 3106/3659/3429/3107/3383/64135/6352/3569/4599/834/3575/330/3576/6376/4314/627/3606/3676 18 3 ENSG00000149968/ENSG00000176697/ENSG00000150782 15 ENSG00000234745/ENSG00000125347/ENSG00000165949/ENSG00000204525/ENSG00000090339/ENSG00000115267/ENSG00000271503/ENSG00000136244/ENSG00000157601/ENSG00000137752/ENSG00000168685/ENSG00000023445/ENSG00000169429/ENSG00000006210/ENSG00000115232 DOID:2237 hepatitis 34/268 349/6421 2.52477068559001e-06 0.00018599144050513 ENSG00000187608/ENSG00000234745/ENSG00000125347/ENSG00000134321/ENSG00000115415/ENSG00000204525/ENSG00000166710/ENSG00000107201/ENSG00000172183/ENSG00000089127/ENSG00000090339/ENSG00000079385/ENSG00000271503/ENSG00000170430/ENSG00000136244/ENSG00000055332/ENSG00000157601/ENSG00000179750/ENSG00000213928/ENSG00000169248/ENSG00000240065/ENSG00000120949/ENSG00000169429/ENSG00000115009/ENSG00000197249/ENSG00000232810/ENSG00000167165/ENSG00000149968/ENSG00000239713/ENSG00000206073/ENSG00000137462/ENSG00000101412/ENSG00000150782/ENSG00000044574 ISG15/HLA-B/IRF1/RSAD2/STAT1/HLA-C/B2M/DDX58/ISG20/OAS1/ICAM1/CEACAM1/CCL5/MGMT/IL6/EIF2AK2/MX1/APOBEC3B/IRF9/CXCL11/PSMB9/TNFRSF8/CXCL8/CCL20/SERPINA1/TNF/UGT1A6/MMP3/APOBEC3G/SERPINB4/TLR2/E2F1/IL18/HSPA5 9636/3106/3659/91543/6772/3107/567/23586/3669/4938/3383/634/6352/4255/3569/5610/4599/9582/10379/6373/5698/943/3576/6364/5265/7124/54578/4314/60489/6318/7097/1869/3606/3309 34 2 ENSG00000149968/ENSG00000150782 32 ENSG00000187608/ENSG00000234745/ENSG00000125347/ENSG00000134321/ENSG00000115415/ENSG00000204525/ENSG00000166710/ENSG00000107201/ENSG00000172183/ENSG00000089127/ENSG00000090339/ENSG00000079385/ENSG00000271503/ENSG00000170430/ENSG00000136244/ENSG00000055332/ENSG00000157601/ENSG00000179750/ENSG00000213928/ENSG00000169248/ENSG00000240065/ENSG00000120949/ENSG00000169429/ENSG00000115009/ENSG00000197249/ENSG00000232810/ENSG00000167165/ENSG00000239713/ENSG00000206073/ENSG00000137462/ENSG00000101412/ENSG00000044574 DOID:381 arthropathy 13/268 70/6421 4.89787567413084e-06 0.000324729157194875 ENSG00000234745/ENSG00000204525/ENSG00000162892/ENSG00000136244/ENSG00000101347/ENSG00000169429/ENSG00000184371/ENSG00000164308/ENSG00000232810/ENSG00000149968/ENSG00000162891/ENSG00000150782/ENSG00000044574 HLA-B/HLA-C/IL24/IL6/SAMHD1/CXCL8/CSF1/ERAP2/TNF/MMP3/IL20/IL18/HSPA5 3106/3107/11009/3569/25939/3576/1435/64167/7124/4314/50604/3606/3309 13 2 ENSG00000149968/ENSG00000150782 11 ENSG00000234745/ENSG00000204525/ENSG00000162892/ENSG00000136244/ENSG00000101347/ENSG00000169429/ENSG00000184371/ENSG00000164308/ENSG00000232810/ENSG00000162891/ENSG00000044574 DOID:1116 pertussis 8/268 26/6421 6.73039791327283e-06 0.000374042200361374 ENSG00000115415/ENSG00000090339/ENSG00000136244/ENSG00000149131/ENSG00000000971/ENSG00000102962/ENSG00000160255/ENSG00000169403 STAT1/ICAM1/IL6/SERPING1/CFH/CCL22/ITGB2/PTAFR 6772/3383/3569/710/3075/6367/3689/5724 8 0 8 ENSG00000115415/ENSG00000090339/ENSG00000136244/ENSG00000149131/ENSG00000000971/ENSG00000102962/ENSG00000160255/ENSG00000169403 DOID:399 tuberculosis 16/268 106/6421 6.76999457667646e-06 0.000374042200361374 ENSG00000234745/ENSG00000125347/ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000137752/ENSG00000169429/ENSG00000135899/ENSG00000115009/ENSG00000163661/ENSG00000232810/ENSG00000149968/ENSG00000102962/ENSG00000008517/ENSG00000137462/ENSG00000150782 HLA-B/IRF1/ICAM1/CCL5/IL6/CASP1/CXCL8/SP110/CCL20/PTX3/TNF/MMP3/CCL22/IL32/TLR2/IL18 3106/3659/3383/6352/3569/834/3576/3431/6364/5806/7124/4314/6367/9235/7097/3606 16 2 ENSG00000149968/ENSG00000150782 14 ENSG00000234745/ENSG00000125347/ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000137752/ENSG00000169429/ENSG00000135899/ENSG00000115009/ENSG00000163661/ENSG00000232810/ENSG00000102962/ENSG00000008517/ENSG00000137462 DOID:0050338 primary bacterial infectious disease 21/268 171/6421 7.40303333895547e-06 0.000377554700286729 ENSG00000234745/ENSG00000125347/ENSG00000090339/ENSG00000079385/ENSG00000271503/ENSG00000136244/ENSG00000137752/ENSG00000169248/ENSG00000240065/ENSG00000169429/ENSG00000135899/ENSG00000204264/ENSG00000115009/ENSG00000163661/ENSG00000232810/ENSG00000149968/ENSG00000111674/ENSG00000102962/ENSG00000008517/ENSG00000137462/ENSG00000150782 HLA-B/IRF1/ICAM1/CEACAM1/CCL5/IL6/CASP1/CXCL11/PSMB9/CXCL8/SP110/PSMB8/CCL20/PTX3/TNF/MMP3/ENO2/CCL22/IL32/TLR2/IL18 3106/3659/3383/634/6352/3569/834/6373/5698/3576/3431/5696/6364/5806/7124/4314/2026/6367/9235/7097/3606 21 2 ENSG00000149968/ENSG00000150782 19 ENSG00000234745/ENSG00000125347/ENSG00000090339/ENSG00000079385/ENSG00000271503/ENSG00000136244/ENSG00000137752/ENSG00000169248/ENSG00000240065/ENSG00000169429/ENSG00000135899/ENSG00000204264/ENSG00000115009/ENSG00000163661/ENSG00000232810/ENSG00000111674/ENSG00000102962/ENSG00000008517/ENSG00000137462 DOID:1883 hepatitis C 22/268 190/6421 1.16822764775649e-05 0.000553239236044679 ENSG00000187608/ENSG00000234745/ENSG00000125347/ENSG00000134321/ENSG00000115415/ENSG00000204525/ENSG00000107201/ENSG00000172183/ENSG00000089127/ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000055332/ENSG00000157601/ENSG00000169248/ENSG00000120949/ENSG00000169429/ENSG00000197249/ENSG00000232810/ENSG00000137462/ENSG00000101412/ENSG00000150782 ISG15/HLA-B/IRF1/RSAD2/STAT1/HLA-C/DDX58/ISG20/OAS1/ICAM1/CCL5/IL6/EIF2AK2/MX1/CXCL11/TNFRSF8/CXCL8/SERPINA1/TNF/TLR2/E2F1/IL18 9636/3106/3659/91543/6772/3107/23586/3669/4938/3383/6352/3569/5610/4599/6373/943/3576/5265/7124/7097/1869/3606 22 1 ENSG00000150782 21 ENSG00000187608/ENSG00000234745/ENSG00000125347/ENSG00000134321/ENSG00000115415/ENSG00000204525/ENSG00000107201/ENSG00000172183/ENSG00000089127/ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000055332/ENSG00000157601/ENSG00000169248/ENSG00000120949/ENSG00000169429/ENSG00000197249/ENSG00000232810/ENSG00000137462/ENSG00000101412 DOID:2349 arteriosclerosis 28/268 280/6421 1.277392499646e-05 0.000564607484843531 ENSG00000134321/ENSG00000166710/ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000168685/ENSG00000163739/ENSG00000173391/ENSG00000076706/ENSG00000006210/ENSG00000184371/ENSG00000000971/ENSG00000163661/ENSG00000232810/ENSG00000157873/ENSG00000205413/ENSG00000149968/ENSG00000181634/ENSG00000146674/ENSG00000008517/ENSG00000162891/ENSG00000104267/ENSG00000137462/ENSG00000129757/ENSG00000150782/ENSG00000163131/ENSG00000199038/ENSG00000241635 RSAD2/B2M/ICAM1/CCL5/IL6/IL7R/CXCL1/OLR1/MCAM/CX3CL1/CSF1/CFH/PTX3/TNF/TNFRSF14/SAMD9/MMP3/TNFSF15/IGFBP3/IL32/IL20/CA2/TLR2/CDKN1C/IL18/CTSS/MIR210/UGT1A1 91543/567/3383/6352/3569/3575/2919/4973/4162/6376/1435/3075/5806/7124/8764/54809/4314/9966/3486/9235/50604/760/7097/1028/3606/1520/406992/54658 28 5 ENSG00000149968/ENSG00000146674/ENSG00000104267/ENSG00000150782/ENSG00000199038 23 ENSG00000134321/ENSG00000166710/ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000168685/ENSG00000163739/ENSG00000173391/ENSG00000076706/ENSG00000006210/ENSG00000184371/ENSG00000000971/ENSG00000163661/ENSG00000232810/ENSG00000157873/ENSG00000205413/ENSG00000181634/ENSG00000008517/ENSG00000162891/ENSG00000137462/ENSG00000129757/ENSG00000163131/ENSG00000241635 DOID:1492 eye and adnexa disease 37/268 429/6421 1.54085927828031e-05 0.000638493563437403 ENSG00000234745/ENSG00000115415/ENSG00000090339/ENSG00000154277/ENSG00000271503/ENSG00000171812/ENSG00000136244/ENSG00000160710/ENSG00000055332/ENSG00000077942/ENSG00000196116/ENSG00000120949/ENSG00000149131/ENSG00000169429/ENSG00000174804/ENSG00000120708/ENSG00000000971/ENSG00000197249/ENSG00000232810/ENSG00000166033/ENSG00000101115/ENSG00000243649/ENSG00000149968/ENSG00000111674/ENSG00000183770/ENSG00000239713/ENSG00000176697/ENSG00000146674/ENSG00000144810/ENSG00000184792/ENSG00000148600/ENSG00000137462/ENSG00000099953/ENSG00000150782/ENSG00000107165/ENSG00000044574/ENSG00000100234 HLA-B/STAT1/ICAM1/UCHL1/CCL5/COL8A2/IL6/ADAR/EIF2AK2/FBLN1/TDRD7/TNFRSF8/SERPING1/CXCL8/FZD4/TGFBI/CFH/SERPINA1/TNF/HTRA1/SALL4/CFB/MMP3/ENO2/FOXL2/APOBEC3G/BDNF/IGFBP3/COL8A1/OSBP2/CDHR1/TLR2/MMP11/IL18/TYRP1/HSPA5/TIMP3 3106/6772/3383/7345/6352/1296/3569/103/5610/2192/23424/943/710/3576/8322/7045/3075/5265/7124/5654/57167/629/4314/2026/668/60489/627/3486/1295/23762/92211/7097/4320/3606/7306/3309/7078 37 9 ENSG00000120708/ENSG00000166033/ENSG00000149968/ENSG00000183770/ENSG00000176697/ENSG00000146674/ENSG00000148600/ENSG00000150782/ENSG00000100234 28 ENSG00000234745/ENSG00000115415/ENSG00000090339/ENSG00000154277/ENSG00000271503/ENSG00000171812/ENSG00000136244/ENSG00000160710/ENSG00000055332/ENSG00000077942/ENSG00000196116/ENSG00000120949/ENSG00000149131/ENSG00000169429/ENSG00000174804/ENSG00000000971/ENSG00000197249/ENSG00000232810/ENSG00000101115/ENSG00000243649/ENSG00000111674/ENSG00000239713/ENSG00000144810/ENSG00000184792/ENSG00000137462/ENSG00000099953/ENSG00000107165/ENSG00000044574 DOID:1176 bronchial disease 16/268 115/6421 1.95952894649712e-05 0.000764216289133875 ENSG00000125347/ENSG00000090339/ENSG00000271503/ENSG00000055332/ENSG00000151882/ENSG00000169429/ENSG00000006210/ENSG00000197249/ENSG00000232810/ENSG00000157873/ENSG00000102962/ENSG00000176697/ENSG00000206073/ENSG00000137462/ENSG00000150782/ENSG00000115232 IRF1/ICAM1/CCL5/EIF2AK2/CCL28/CXCL8/CX3CL1/SERPINA1/TNF/TNFRSF14/CCL22/BDNF/SERPINB4/TLR2/IL18/ITGA4 3659/3383/6352/5610/56477/3576/6376/5265/7124/8764/6367/627/6318/7097/3606/3676 16 2 ENSG00000176697/ENSG00000150782 14 ENSG00000125347/ENSG00000090339/ENSG00000271503/ENSG00000055332/ENSG00000151882/ENSG00000169429/ENSG00000006210/ENSG00000197249/ENSG00000232810/ENSG00000157873/ENSG00000102962/ENSG00000206073/ENSG00000137462/ENSG00000115232 DOID:1724 duodenal ulcer 6/268 16/6421 2.81155760900629e-05 0.00103559038598398 ENSG00000136244/ENSG00000169429/ENSG00000232810/ENSG00000149968/ENSG00000239713/ENSG00000137462 IL6/CXCL8/TNF/MMP3/APOBEC3G/TLR2 3569/3576/7124/4314/60489/7097 6 1 ENSG00000149968 5 ENSG00000136244/ENSG00000169429/ENSG00000232810/ENSG00000239713/ENSG00000137462 DOID:1123 spondyloarthropathy 10/268 52/6421 4.53721755385918e-05 0.00151985995956878 ENSG00000234745/ENSG00000204525/ENSG00000162892/ENSG00000136244/ENSG00000164308/ENSG00000232810/ENSG00000149968/ENSG00000162891/ENSG00000150782/ENSG00000044574 HLA-B/HLA-C/IL24/IL6/ERAP2/TNF/MMP3/IL20/IL18/HSPA5 3106/3107/11009/3569/64167/7124/4314/50604/3606/3309 10 2 ENSG00000149968/ENSG00000150782 8 ENSG00000234745/ENSG00000204525/ENSG00000162892/ENSG00000136244/ENSG00000164308/ENSG00000232810/ENSG00000162891/ENSG00000044574 DOID:321 tropical spastic paraparesis 5/268 11/6421 4.58479625812603e-05 0.00151985995956878 ENSG00000204525/ENSG00000100285/ENSG00000136244/ENSG00000164136/ENSG00000277586 HLA-C/NEFH/IL6/IL15/NEFL 3107/4744/3569/3600/4747 5 1 ENSG00000277586 4 ENSG00000204525/ENSG00000100285/ENSG00000136244/ENSG00000164136 DOID:37 skin disease 26/268 271/6421 5.42573845006022e-05 0.00159143400738441 ENSG00000234745/ENSG00000090339/ENSG00000271503/ENSG00000162892/ENSG00000136244/ENSG00000168685/ENSG00000151882/ENSG00000149131/ENSG00000169429/ENSG00000006210/ENSG00000011201/ENSG00000232810/ENSG00000157873/ENSG00000206337/ENSG00000164136/ENSG00000149968/ENSG00000102962/ENSG00000176697/ENSG00000146674/ENSG00000008517/ENSG00000128342/ENSG00000167768/ENSG00000162891/ENSG00000206073/ENSG00000137462/ENSG00000150782 HLA-B/ICAM1/CCL5/IL24/IL6/IL7R/CCL28/SERPING1/CXCL8/CX3CL1/ANOS1/TNF/TNFRSF14/HCP5/IL15/MMP3/CCL22/BDNF/IGFBP3/IL32/LIF/KRT1/IL20/SERPINB4/TLR2/IL18 3106/3383/6352/11009/3569/3575/56477/710/3576/6376/3730/7124/8764/10866/3600/4314/6367/627/3486/9235/3976/3848/50604/6318/7097/3606 26 5 ENSG00000149968/ENSG00000176697/ENSG00000146674/ENSG00000167768/ENSG00000150782 21 ENSG00000234745/ENSG00000090339/ENSG00000271503/ENSG00000162892/ENSG00000136244/ENSG00000168685/ENSG00000151882/ENSG00000149131/ENSG00000169429/ENSG00000006210/ENSG00000011201/ENSG00000232810/ENSG00000157873/ENSG00000206337/ENSG00000164136/ENSG00000102962/ENSG00000008517/ENSG00000128342/ENSG00000162891/ENSG00000206073/ENSG00000137462 DOID:2320 obstructive lung disease 24/268 240/6421 5.48429708186405e-05 0.00159143400738441 ENSG00000125347/ENSG00000115415/ENSG00000090339/ENSG00000271503/ENSG00000094804/ENSG00000136244/ENSG00000055332/ENSG00000151882/ENSG00000169248/ENSG00000169429/ENSG00000006210/ENSG00000197249/ENSG00000232810/ENSG00000157873/ENSG00000149968/ENSG00000102962/ENSG00000176697/ENSG00000206073/ENSG00000160255/ENSG00000137462/ENSG00000150782/ENSG00000163131/ENSG00000115232/ENSG00000069702 IRF1/STAT1/ICAM1/CCL5/CDC6/IL6/EIF2AK2/CCL28/CXCL11/CXCL8/CX3CL1/SERPINA1/TNF/TNFRSF14/MMP3/CCL22/BDNF/SERPINB4/ITGB2/TLR2/IL18/CTSS/ITGA4/TGFBR3 3659/6772/3383/6352/990/3569/5610/56477/6373/3576/6376/5265/7124/8764/4314/6367/627/6318/3689/7097/3606/1520/3676/7049 24 4 ENSG00000149968/ENSG00000176697/ENSG00000150782/ENSG00000069702 20 ENSG00000125347/ENSG00000115415/ENSG00000090339/ENSG00000271503/ENSG00000094804/ENSG00000136244/ENSG00000055332/ENSG00000151882/ENSG00000169248/ENSG00000169429/ENSG00000006210/ENSG00000197249/ENSG00000232810/ENSG00000157873/ENSG00000102962/ENSG00000206073/ENSG00000160255/ENSG00000137462/ENSG00000163131/ENSG00000115232 DOID:5614 eye disease 35/268 420/6421 5.520811790323e-05 0.00159143400738441 ENSG00000234745/ENSG00000115415/ENSG00000090339/ENSG00000154277/ENSG00000271503/ENSG00000171812/ENSG00000136244/ENSG00000160710/ENSG00000055332/ENSG00000077942/ENSG00000196116/ENSG00000120949/ENSG00000149131/ENSG00000169429/ENSG00000174804/ENSG00000120708/ENSG00000000971/ENSG00000197249/ENSG00000232810/ENSG00000166033/ENSG00000101115/ENSG00000243649/ENSG00000149968/ENSG00000111674/ENSG00000239713/ENSG00000176697/ENSG00000146674/ENSG00000144810/ENSG00000184792/ENSG00000148600/ENSG00000137462/ENSG00000099953/ENSG00000107165/ENSG00000044574/ENSG00000100234 HLA-B/STAT1/ICAM1/UCHL1/CCL5/COL8A2/IL6/ADAR/EIF2AK2/FBLN1/TDRD7/TNFRSF8/SERPING1/CXCL8/FZD4/TGFBI/CFH/SERPINA1/TNF/HTRA1/SALL4/CFB/MMP3/ENO2/APOBEC3G/BDNF/IGFBP3/COL8A1/OSBP2/CDHR1/TLR2/MMP11/TYRP1/HSPA5/TIMP3 3106/6772/3383/7345/6352/1296/3569/103/5610/2192/23424/943/710/3576/8322/7045/3075/5265/7124/5654/57167/629/4314/2026/60489/627/3486/1295/23762/92211/7097/4320/7306/3309/7078 35 7 ENSG00000120708/ENSG00000166033/ENSG00000149968/ENSG00000176697/ENSG00000146674/ENSG00000148600/ENSG00000100234 28 ENSG00000234745/ENSG00000115415/ENSG00000090339/ENSG00000154277/ENSG00000271503/ENSG00000171812/ENSG00000136244/ENSG00000160710/ENSG00000055332/ENSG00000077942/ENSG00000196116/ENSG00000120949/ENSG00000149131/ENSG00000169429/ENSG00000174804/ENSG00000000971/ENSG00000197249/ENSG00000232810/ENSG00000101115/ENSG00000243649/ENSG00000111674/ENSG00000239713/ENSG00000144810/ENSG00000184792/ENSG00000137462/ENSG00000099953/ENSG00000107165/ENSG00000044574 DOID:3310 atopic dermatitis 14/268 100/6421 6.07959700947099e-05 0.00167314726249281 ENSG00000271503/ENSG00000168685/ENSG00000151882/ENSG00000006210/ENSG00000011201/ENSG00000232810/ENSG00000157873/ENSG00000164136/ENSG00000102962/ENSG00000176697/ENSG00000008517/ENSG00000206073/ENSG00000137462/ENSG00000150782 CCL5/IL7R/CCL28/CX3CL1/ANOS1/TNF/TNFRSF14/IL15/CCL22/BDNF/IL32/SERPINB4/TLR2/IL18 6352/3575/56477/6376/3730/7124/8764/3600/6367/627/9235/6318/7097/3606 14 2 ENSG00000176697/ENSG00000150782 12 ENSG00000271503/ENSG00000168685/ENSG00000151882/ENSG00000006210/ENSG00000011201/ENSG00000232810/ENSG00000157873/ENSG00000164136/ENSG00000102962/ENSG00000008517/ENSG00000206073/ENSG00000137462 DOID:0050155 sensory system disease 38/268 475/6421 6.30900174393969e-05 0.00167314726249281 ENSG00000234745/ENSG00000115415/ENSG00000090339/ENSG00000154277/ENSG00000271503/ENSG00000171812/ENSG00000136244/ENSG00000160710/ENSG00000055332/ENSG00000077942/ENSG00000196116/ENSG00000120949/ENSG00000149131/ENSG00000169429/ENSG00000174804/ENSG00000120708/ENSG00000000971/ENSG00000197249/ENSG00000232810/ENSG00000166033/ENSG00000101115/ENSG00000243649/ENSG00000149968/ENSG00000111674/ENSG00000183770/ENSG00000239713/ENSG00000176697/ENSG00000146674/ENSG00000144810/ENSG00000184792/ENSG00000148600/ENSG00000137462/ENSG00000099953/ENSG00000150782/ENSG00000107165/ENSG00000044574/ENSG00000117013/ENSG00000100234 HLA-B/STAT1/ICAM1/UCHL1/CCL5/COL8A2/IL6/ADAR/EIF2AK2/FBLN1/TDRD7/TNFRSF8/SERPING1/CXCL8/FZD4/TGFBI/CFH/SERPINA1/TNF/HTRA1/SALL4/CFB/MMP3/ENO2/FOXL2/APOBEC3G/BDNF/IGFBP3/COL8A1/OSBP2/CDHR1/TLR2/MMP11/IL18/TYRP1/HSPA5/KCNQ4/TIMP3 3106/6772/3383/7345/6352/1296/3569/103/5610/2192/23424/943/710/3576/8322/7045/3075/5265/7124/5654/57167/629/4314/2026/668/60489/627/3486/1295/23762/92211/7097/4320/3606/7306/3309/9132/7078 38 9 ENSG00000120708/ENSG00000166033/ENSG00000149968/ENSG00000183770/ENSG00000176697/ENSG00000146674/ENSG00000148600/ENSG00000150782/ENSG00000100234 29 ENSG00000234745/ENSG00000115415/ENSG00000090339/ENSG00000154277/ENSG00000271503/ENSG00000171812/ENSG00000136244/ENSG00000160710/ENSG00000055332/ENSG00000077942/ENSG00000196116/ENSG00000120949/ENSG00000149131/ENSG00000169429/ENSG00000174804/ENSG00000000971/ENSG00000197249/ENSG00000232810/ENSG00000101115/ENSG00000243649/ENSG00000111674/ENSG00000239713/ENSG00000144810/ENSG00000184792/ENSG00000137462/ENSG00000099953/ENSG00000107165/ENSG00000044574/ENSG00000117013 DOID:219 colon cancer 24/268 245/6421 7.63563264513844e-05 0.0019470863245103 ENSG00000115415/ENSG00000108679/ENSG00000090339/ENSG00000128567/ENSG00000079385/ENSG00000131196/ENSG00000023445/ENSG00000126561/ENSG00000136167/ENSG00000081041/ENSG00000169429/ENSG00000025708/ENSG00000232810/ENSG00000142089/ENSG00000164136/ENSG00000008516/ENSG00000146674/ENSG00000188641/ENSG00000099250/ENSG00000108947/ENSG00000135480/ENSG00000163734/ENSG00000100234/ENSG00000156413 STAT1/LGALS3BP/ICAM1/PODXL/CEACAM1/NFATC1/BIRC3/STAT5A/LCP1/CXCL2/CXCL8/TYMP/TNF/IFITM3/IL15/MMP25/IGFBP3/DPYD/NRP1/EFNB3/KRT7/CXCL3/TIMP3/FUT6 6772/3959/3383/5420/634/4772/330/6776/3936/2920/3576/1890/7124/10410/3600/64386/3486/1806/8829/1949/3855/2921/7078/2528 24 3 ENSG00000146674/ENSG00000108947/ENSG00000100234 21 ENSG00000115415/ENSG00000108679/ENSG00000090339/ENSG00000128567/ENSG00000079385/ENSG00000131196/ENSG00000023445/ENSG00000126561/ENSG00000136167/ENSG00000081041/ENSG00000169429/ENSG00000025708/ENSG00000232810/ENSG00000142089/ENSG00000164136/ENSG00000008516/ENSG00000188641/ENSG00000099250/ENSG00000135480/ENSG00000163734/ENSG00000156413 DOID:7148 rheumatoid arthritis 35/268 428/6421 8.1309789833265e-05 0.00199660706146129 ENSG00000204525/ENSG00000090339/ENSG00000115267/ENSG00000271503/ENSG00000162892/ENSG00000136244/ENSG00000131196/ENSG00000168685/ENSG00000120949/ENSG00000133321/ENSG00000169429/ENSG00000006210/ENSG00000120708/ENSG00000197646/ENSG00000000971/ENSG00000115009/ENSG00000197249/ENSG00000232810/ENSG00000157873/ENSG00000164136/ENSG00000149968/ENSG00000181634/ENSG00000102962/ENSG00000008517/ENSG00000138378/ENSG00000162891/ENSG00000160255/ENSG00000137462/ENSG00000213694/ENSG00000150782/ENSG00000163131/ENSG00000078081/ENSG00000044574/ENSG00000100234/ENSG00000115232 HLA-C/ICAM1/IFIH1/CCL5/IL24/IL6/NFATC1/IL7R/TNFRSF8/RARRES3/CXCL8/CX3CL1/TGFBI/PDCD1LG2/CFH/CCL20/SERPINA1/TNF/TNFRSF14/IL15/MMP3/TNFSF15/CCL22/IL32/STAT4/IL20/ITGB2/TLR2/S1PR3/IL18/CTSS/LAMP3/HSPA5/TIMP3/ITGA4 3107/3383/64135/6352/11009/3569/4772/3575/943/5920/3576/6376/7045/80380/3075/6364/5265/7124/8764/3600/4314/9966/6367/9235/6775/50604/3689/7097/1903/3606/1520/27074/3309/7078/3676 35 4 ENSG00000120708/ENSG00000149968/ENSG00000150782/ENSG00000100234 31 ENSG00000204525/ENSG00000090339/ENSG00000115267/ENSG00000271503/ENSG00000162892/ENSG00000136244/ENSG00000131196/ENSG00000168685/ENSG00000120949/ENSG00000133321/ENSG00000169429/ENSG00000006210/ENSG00000197646/ENSG00000000971/ENSG00000115009/ENSG00000197249/ENSG00000232810/ENSG00000157873/ENSG00000164136/ENSG00000181634/ENSG00000102962/ENSG00000008517/ENSG00000138378/ENSG00000162891/ENSG00000160255/ENSG00000137462/ENSG00000213694/ENSG00000163131/ENSG00000078081/ENSG00000044574/ENSG00000115232 DOID:9256 colorectal cancer 24/268 249/6421 9.87093854746878e-05 0.00223220830019559 ENSG00000115415/ENSG00000108679/ENSG00000090339/ENSG00000128567/ENSG00000079385/ENSG00000131196/ENSG00000023445/ENSG00000126561/ENSG00000136167/ENSG00000081041/ENSG00000169429/ENSG00000025708/ENSG00000232810/ENSG00000142089/ENSG00000164136/ENSG00000008516/ENSG00000146674/ENSG00000188641/ENSG00000099250/ENSG00000108947/ENSG00000135480/ENSG00000163734/ENSG00000100234/ENSG00000156413 STAT1/LGALS3BP/ICAM1/PODXL/CEACAM1/NFATC1/BIRC3/STAT5A/LCP1/CXCL2/CXCL8/TYMP/TNF/IFITM3/IL15/MMP25/IGFBP3/DPYD/NRP1/EFNB3/KRT7/CXCL3/TIMP3/FUT6 6772/3959/3383/5420/634/4772/330/6776/3936/2920/3576/1890/7124/10410/3600/64386/3486/1806/8829/1949/3855/2921/7078/2528 24 3 ENSG00000146674/ENSG00000108947/ENSG00000100234 21 ENSG00000115415/ENSG00000108679/ENSG00000090339/ENSG00000128567/ENSG00000079385/ENSG00000131196/ENSG00000023445/ENSG00000126561/ENSG00000136167/ENSG00000081041/ENSG00000169429/ENSG00000025708/ENSG00000232810/ENSG00000142089/ENSG00000164136/ENSG00000008516/ENSG00000188641/ENSG00000099250/ENSG00000135480/ENSG00000163734/ENSG00000156413 DOID:612 primary immunodeficiency disease 18/268 159/6421 0.000100042027765687 0.00223220830019559 ENSG00000115415/ENSG00000130303/ENSG00000271503/ENSG00000136244/ENSG00000160710/ENSG00000168685/ENSG00000120949/ENSG00000006210/ENSG00000171843/ENSG00000135899/ENSG00000197249/ENSG00000232810/ENSG00000164136/ENSG00000239713/ENSG00000128394/ENSG00000160255/ENSG00000137462/ENSG00000241635 STAT1/BST2/CCL5/IL6/ADAR/IL7R/TNFRSF8/CX3CL1/MLLT3/SP110/SERPINA1/TNF/IL15/APOBEC3G/APOBEC3F/ITGB2/TLR2/UGT1A1 6772/684/6352/3569/103/3575/943/6376/4300/3431/5265/7124/3600/60489/200316/3689/7097/54658 18 1 ENSG00000171843 17 ENSG00000115415/ENSG00000130303/ENSG00000271503/ENSG00000136244/ENSG00000160710/ENSG00000168685/ENSG00000120949/ENSG00000006210/ENSG00000135899/ENSG00000197249/ENSG00000232810/ENSG00000164136/ENSG00000239713/ENSG00000128394/ENSG00000160255/ENSG00000137462/ENSG00000241635 DOID:1520 colon carcinoma 17/268 145/6421 0.000101004900461339 0.00223220830019559 ENSG00000115415/ENSG00000128567/ENSG00000131196/ENSG00000126561/ENSG00000081041/ENSG00000169429/ENSG00000025708/ENSG00000232810/ENSG00000164136/ENSG00000146674/ENSG00000188641/ENSG00000099250/ENSG00000108947/ENSG00000135480/ENSG00000163734/ENSG00000100234/ENSG00000156413 STAT1/PODXL/NFATC1/STAT5A/CXCL2/CXCL8/TYMP/TNF/IL15/IGFBP3/DPYD/NRP1/EFNB3/KRT7/CXCL3/TIMP3/FUT6 6772/5420/4772/6776/2920/3576/1890/7124/3600/3486/1806/8829/1949/3855/2921/7078/2528 17 3 ENSG00000146674/ENSG00000108947/ENSG00000100234 14 ENSG00000115415/ENSG00000128567/ENSG00000131196/ENSG00000126561/ENSG00000081041/ENSG00000169429/ENSG00000025708/ENSG00000232810/ENSG00000164136/ENSG00000188641/ENSG00000099250/ENSG00000135480/ENSG00000163734/ENSG00000156413 DOID:5672 large intestine cancer 24/268 250/6421 0.000105140264207189 0.00224864500546344 ENSG00000115415/ENSG00000108679/ENSG00000090339/ENSG00000128567/ENSG00000079385/ENSG00000131196/ENSG00000023445/ENSG00000126561/ENSG00000136167/ENSG00000081041/ENSG00000169429/ENSG00000025708/ENSG00000232810/ENSG00000142089/ENSG00000164136/ENSG00000008516/ENSG00000146674/ENSG00000188641/ENSG00000099250/ENSG00000108947/ENSG00000135480/ENSG00000163734/ENSG00000100234/ENSG00000156413 STAT1/LGALS3BP/ICAM1/PODXL/CEACAM1/NFATC1/BIRC3/STAT5A/LCP1/CXCL2/CXCL8/TYMP/TNF/IFITM3/IL15/MMP25/IGFBP3/DPYD/NRP1/EFNB3/KRT7/CXCL3/TIMP3/FUT6 6772/3959/3383/5420/634/4772/330/6776/3936/2920/3576/1890/7124/10410/3600/64386/3486/1806/8829/1949/3855/2921/7078/2528 24 3 ENSG00000146674/ENSG00000108947/ENSG00000100234 21 ENSG00000115415/ENSG00000108679/ENSG00000090339/ENSG00000128567/ENSG00000079385/ENSG00000131196/ENSG00000023445/ENSG00000126561/ENSG00000136167/ENSG00000081041/ENSG00000169429/ENSG00000025708/ENSG00000232810/ENSG00000142089/ENSG00000164136/ENSG00000008516/ENSG00000188641/ENSG00000099250/ENSG00000135480/ENSG00000163734/ENSG00000156413 DOID:1579 respiratory system disease 35/268 436/6421 0.000118150562034944 0.00239467578180538 ENSG00000234745/ENSG00000125347/ENSG00000165949/ENSG00000115415/ENSG00000204525/ENSG00000090339/ENSG00000115267/ENSG00000271503/ENSG00000094804/ENSG00000136244/ENSG00000055332/ENSG00000151882/ENSG00000169248/ENSG00000120949/ENSG00000076706/ENSG00000169429/ENSG00000006210/ENSG00000184371/ENSG00000197249/ENSG00000163661/ENSG00000232810/ENSG00000157873/ENSG00000149968/ENSG00000102962/ENSG00000176697/ENSG00000146674/ENSG00000206073/ENSG00000160255/ENSG00000137462/ENSG00000145147/ENSG00000150782/ENSG00000163131/ENSG00000100234/ENSG00000115232/ENSG00000069702 HLA-B/IRF1/IFI27/STAT1/HLA-C/ICAM1/IFIH1/CCL5/CDC6/IL6/EIF2AK2/CCL28/CXCL11/TNFRSF8/MCAM/CXCL8/CX3CL1/CSF1/SERPINA1/PTX3/TNF/TNFRSF14/MMP3/CCL22/BDNF/IGFBP3/SERPINB4/ITGB2/TLR2/SLIT2/IL18/CTSS/TIMP3/ITGA4/TGFBR3 3106/3659/3429/6772/3107/3383/64135/6352/990/3569/5610/56477/6373/943/4162/3576/6376/1435/5265/5806/7124/8764/4314/6367/627/3486/6318/3689/7097/9353/3606/1520/7078/3676/7049 35 6 ENSG00000149968/ENSG00000176697/ENSG00000146674/ENSG00000150782/ENSG00000100234/ENSG00000069702 29 ENSG00000234745/ENSG00000125347/ENSG00000165949/ENSG00000115415/ENSG00000204525/ENSG00000090339/ENSG00000115267/ENSG00000271503/ENSG00000094804/ENSG00000136244/ENSG00000055332/ENSG00000151882/ENSG00000169248/ENSG00000120949/ENSG00000076706/ENSG00000169429/ENSG00000006210/ENSG00000184371/ENSG00000197249/ENSG00000163661/ENSG00000232810/ENSG00000157873/ENSG00000102962/ENSG00000206073/ENSG00000160255/ENSG00000137462/ENSG00000145147/ENSG00000163131/ENSG00000115232 DOID:4248 coronary stenosis 5/268 13/6421 0.000119192007239182 0.00239467578180538 ENSG00000090339/ENSG00000136244/ENSG00000232810/ENSG00000149968/ENSG00000137462 ICAM1/IL6/TNF/MMP3/TLR2 3383/3569/7124/4314/7097 5 1 ENSG00000149968 4 ENSG00000090339/ENSG00000136244/ENSG00000232810/ENSG00000137462 DOID:850 lung disease 32/268 389/6421 0.000150684676415264 0.00287378982714135 ENSG00000125347/ENSG00000165949/ENSG00000115415/ENSG00000090339/ENSG00000115267/ENSG00000271503/ENSG00000094804/ENSG00000136244/ENSG00000055332/ENSG00000151882/ENSG00000169248/ENSG00000120949/ENSG00000169429/ENSG00000006210/ENSG00000184371/ENSG00000197249/ENSG00000163661/ENSG00000232810/ENSG00000157873/ENSG00000149968/ENSG00000102962/ENSG00000176697/ENSG00000146674/ENSG00000206073/ENSG00000160255/ENSG00000137462/ENSG00000145147/ENSG00000150782/ENSG00000163131/ENSG00000100234/ENSG00000115232/ENSG00000069702 IRF1/IFI27/STAT1/ICAM1/IFIH1/CCL5/CDC6/IL6/EIF2AK2/CCL28/CXCL11/TNFRSF8/CXCL8/CX3CL1/CSF1/SERPINA1/PTX3/TNF/TNFRSF14/MMP3/CCL22/BDNF/IGFBP3/SERPINB4/ITGB2/TLR2/SLIT2/IL18/CTSS/TIMP3/ITGA4/TGFBR3 3659/3429/6772/3383/64135/6352/990/3569/5610/56477/6373/943/3576/6376/1435/5265/5806/7124/8764/4314/6367/627/3486/6318/3689/7097/9353/3606/1520/7078/3676/7049 32 6 ENSG00000149968/ENSG00000176697/ENSG00000146674/ENSG00000150782/ENSG00000100234/ENSG00000069702 26 ENSG00000125347/ENSG00000165949/ENSG00000115415/ENSG00000090339/ENSG00000115267/ENSG00000271503/ENSG00000094804/ENSG00000136244/ENSG00000055332/ENSG00000151882/ENSG00000169248/ENSG00000120949/ENSG00000169429/ENSG00000006210/ENSG00000184371/ENSG00000197249/ENSG00000163661/ENSG00000232810/ENSG00000157873/ENSG00000102962/ENSG00000206073/ENSG00000160255/ENSG00000137462/ENSG00000145147/ENSG00000163131/ENSG00000115232 DOID:1936 atherosclerosis 25/268 272/6421 0.000151708361915456 0.00287378982714135 ENSG00000134321/ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000168685/ENSG00000163739/ENSG00000173391/ENSG00000006210/ENSG00000184371/ENSG00000000971/ENSG00000163661/ENSG00000232810/ENSG00000157873/ENSG00000205413/ENSG00000149968/ENSG00000181634/ENSG00000146674/ENSG00000008517/ENSG00000162891/ENSG00000104267/ENSG00000137462/ENSG00000129757/ENSG00000150782/ENSG00000163131/ENSG00000199038 RSAD2/ICAM1/CCL5/IL6/IL7R/CXCL1/OLR1/CX3CL1/CSF1/CFH/PTX3/TNF/TNFRSF14/SAMD9/MMP3/TNFSF15/IGFBP3/IL32/IL20/CA2/TLR2/CDKN1C/IL18/CTSS/MIR210 91543/3383/6352/3569/3575/2919/4973/6376/1435/3075/5806/7124/8764/54809/4314/9966/3486/9235/50604/760/7097/1028/3606/1520/406992 25 5 ENSG00000149968/ENSG00000146674/ENSG00000104267/ENSG00000150782/ENSG00000199038 20 ENSG00000134321/ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000168685/ENSG00000163739/ENSG00000173391/ENSG00000006210/ENSG00000184371/ENSG00000000971/ENSG00000163661/ENSG00000232810/ENSG00000157873/ENSG00000205413/ENSG00000181634/ENSG00000008517/ENSG00000162891/ENSG00000137462/ENSG00000129757/ENSG00000163131 DOID:2348 arteriosclerotic cardiovascular disease 25/268 273/6421 0.000160804046716368 0.00296147452702645 ENSG00000134321/ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000168685/ENSG00000163739/ENSG00000173391/ENSG00000006210/ENSG00000184371/ENSG00000000971/ENSG00000163661/ENSG00000232810/ENSG00000157873/ENSG00000205413/ENSG00000149968/ENSG00000181634/ENSG00000146674/ENSG00000008517/ENSG00000162891/ENSG00000104267/ENSG00000137462/ENSG00000129757/ENSG00000150782/ENSG00000163131/ENSG00000199038 RSAD2/ICAM1/CCL5/IL6/IL7R/CXCL1/OLR1/CX3CL1/CSF1/CFH/PTX3/TNF/TNFRSF14/SAMD9/MMP3/TNFSF15/IGFBP3/IL32/IL20/CA2/TLR2/CDKN1C/IL18/CTSS/MIR210 91543/3383/6352/3569/3575/2919/4973/6376/1435/3075/5806/7124/8764/54809/4314/9966/3486/9235/50604/760/7097/1028/3606/1520/406992 25 5 ENSG00000149968/ENSG00000146674/ENSG00000104267/ENSG00000150782/ENSG00000199038 20 ENSG00000134321/ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000168685/ENSG00000163739/ENSG00000173391/ENSG00000006210/ENSG00000184371/ENSG00000000971/ENSG00000163661/ENSG00000232810/ENSG00000157873/ENSG00000205413/ENSG00000181634/ENSG00000008517/ENSG00000162891/ENSG00000137462/ENSG00000129757/ENSG00000163131 DOID:16 integumentary system disease 27/268 308/6421 0.000181884563115672 0.00317759597512578 ENSG00000234745/ENSG00000090339/ENSG00000271503/ENSG00000162892/ENSG00000136244/ENSG00000168685/ENSG00000151882/ENSG00000149131/ENSG00000169429/ENSG00000006210/ENSG00000011201/ENSG00000232810/ENSG00000157873/ENSG00000206337/ENSG00000164136/ENSG00000149968/ENSG00000102962/ENSG00000176697/ENSG00000146674/ENSG00000008517/ENSG00000128342/ENSG00000167768/ENSG00000162891/ENSG00000206073/ENSG00000137462/ENSG00000150782/ENSG00000171346 HLA-B/ICAM1/CCL5/IL24/IL6/IL7R/CCL28/SERPING1/CXCL8/CX3CL1/ANOS1/TNF/TNFRSF14/HCP5/IL15/MMP3/CCL22/BDNF/IGFBP3/IL32/LIF/KRT1/IL20/SERPINB4/TLR2/IL18/KRT15 3106/3383/6352/11009/3569/3575/56477/710/3576/6376/3730/7124/8764/10866/3600/4314/6367/627/3486/9235/3976/3848/50604/6318/7097/3606/3866 27 6 ENSG00000149968/ENSG00000176697/ENSG00000146674/ENSG00000167768/ENSG00000150782/ENSG00000171346 21 ENSG00000234745/ENSG00000090339/ENSG00000271503/ENSG00000162892/ENSG00000136244/ENSG00000168685/ENSG00000151882/ENSG00000149131/ENSG00000169429/ENSG00000006210/ENSG00000011201/ENSG00000232810/ENSG00000157873/ENSG00000206337/ENSG00000164136/ENSG00000102962/ENSG00000008517/ENSG00000128342/ENSG00000162891/ENSG00000206073/ENSG00000137462 DOID:10155 intestinal cancer 24/268 259/6421 0.000182124656191221 0.00317759597512578 ENSG00000115415/ENSG00000108679/ENSG00000090339/ENSG00000128567/ENSG00000079385/ENSG00000131196/ENSG00000023445/ENSG00000126561/ENSG00000136167/ENSG00000081041/ENSG00000169429/ENSG00000025708/ENSG00000232810/ENSG00000142089/ENSG00000164136/ENSG00000008516/ENSG00000146674/ENSG00000188641/ENSG00000099250/ENSG00000108947/ENSG00000135480/ENSG00000163734/ENSG00000100234/ENSG00000156413 STAT1/LGALS3BP/ICAM1/PODXL/CEACAM1/NFATC1/BIRC3/STAT5A/LCP1/CXCL2/CXCL8/TYMP/TNF/IFITM3/IL15/MMP25/IGFBP3/DPYD/NRP1/EFNB3/KRT7/CXCL3/TIMP3/FUT6 6772/3959/3383/5420/634/4772/330/6776/3936/2920/3576/1890/7124/10410/3600/64386/3486/1806/8829/1949/3855/2921/7078/2528 24 3 ENSG00000146674/ENSG00000108947/ENSG00000100234 21 ENSG00000115415/ENSG00000108679/ENSG00000090339/ENSG00000128567/ENSG00000079385/ENSG00000131196/ENSG00000023445/ENSG00000126561/ENSG00000136167/ENSG00000081041/ENSG00000169429/ENSG00000025708/ENSG00000232810/ENSG00000142089/ENSG00000164136/ENSG00000008516/ENSG00000188641/ENSG00000099250/ENSG00000135480/ENSG00000163734/ENSG00000156413 DOID:4195 hyperglycemia 14/268 112/6421 0.000210896364270501 0.00346598332128781 ENSG00000090339/ENSG00000154277/ENSG00000271503/ENSG00000128602/ENSG00000178445/ENSG00000136244/ENSG00000076706/ENSG00000117594/ENSG00000169429/ENSG00000000971/ENSG00000232810/ENSG00000243649/ENSG00000137462/ENSG00000150782 ICAM1/UCHL1/CCL5/SMO/GLDC/IL6/MCAM/HSD11B1/CXCL8/CFH/TNF/CFB/TLR2/IL18 3383/7345/6352/6608/2731/3569/4162/3290/3576/3075/7124/629/7097/3606 14 1 ENSG00000150782 13 ENSG00000090339/ENSG00000154277/ENSG00000271503/ENSG00000128602/ENSG00000178445/ENSG00000136244/ENSG00000076706/ENSG00000117594/ENSG00000169429/ENSG00000000971/ENSG00000232810/ENSG00000243649/ENSG00000137462 DOID:2841 asthma 13/268 99/6421 0.000215786813853722 0.00346598332128781 ENSG00000125347/ENSG00000090339/ENSG00000271503/ENSG00000151882/ENSG00000169429/ENSG00000006210/ENSG00000157873/ENSG00000102962/ENSG00000176697/ENSG00000206073/ENSG00000137462/ENSG00000150782/ENSG00000115232 IRF1/ICAM1/CCL5/CCL28/CXCL8/CX3CL1/TNFRSF14/CCL22/BDNF/SERPINB4/TLR2/IL18/ITGA4 3659/3383/6352/56477/3576/6376/8764/6367/627/6318/7097/3606/3676 13 2 ENSG00000176697/ENSG00000150782 11 ENSG00000125347/ENSG00000090339/ENSG00000271503/ENSG00000151882/ENSG00000169429/ENSG00000006210/ENSG00000157873/ENSG00000102962/ENSG00000206073/ENSG00000137462/ENSG00000115232 DOID:3388 periodontal disease 13/268 99/6421 0.000215786813853722 0.00346598332128781 ENSG00000234745/ENSG00000271503/ENSG00000162892/ENSG00000136244/ENSG00000131196/ENSG00000169429/ENSG00000184371/ENSG00000115009/ENSG00000232810/ENSG00000164136/ENSG00000149968/ENSG00000137462/ENSG00000150782 HLA-B/CCL5/IL24/IL6/NFATC1/CXCL8/CSF1/CCL20/TNF/IL15/MMP3/TLR2/IL18 3106/6352/11009/3569/4772/3576/1435/6364/7124/3600/4314/7097/3606 13 2 ENSG00000149968/ENSG00000150782 11 ENSG00000234745/ENSG00000271503/ENSG00000162892/ENSG00000136244/ENSG00000131196/ENSG00000169429/ENSG00000184371/ENSG00000115009/ENSG00000232810/ENSG00000164136/ENSG00000137462 DOID:0050161 lower respiratory tract disease 32/268 397/6421 0.000219564554289726 0.00346598332128781 ENSG00000125347/ENSG00000165949/ENSG00000115415/ENSG00000090339/ENSG00000115267/ENSG00000271503/ENSG00000094804/ENSG00000136244/ENSG00000055332/ENSG00000151882/ENSG00000169248/ENSG00000120949/ENSG00000169429/ENSG00000006210/ENSG00000184371/ENSG00000197249/ENSG00000163661/ENSG00000232810/ENSG00000157873/ENSG00000149968/ENSG00000102962/ENSG00000176697/ENSG00000146674/ENSG00000206073/ENSG00000160255/ENSG00000137462/ENSG00000145147/ENSG00000150782/ENSG00000163131/ENSG00000100234/ENSG00000115232/ENSG00000069702 IRF1/IFI27/STAT1/ICAM1/IFIH1/CCL5/CDC6/IL6/EIF2AK2/CCL28/CXCL11/TNFRSF8/CXCL8/CX3CL1/CSF1/SERPINA1/PTX3/TNF/TNFRSF14/MMP3/CCL22/BDNF/IGFBP3/SERPINB4/ITGB2/TLR2/SLIT2/IL18/CTSS/TIMP3/ITGA4/TGFBR3 3659/3429/6772/3383/64135/6352/990/3569/5610/56477/6373/943/3576/6376/1435/5265/5806/7124/8764/4314/6367/627/3486/6318/3689/7097/9353/3606/1520/7078/3676/7049 32 6 ENSG00000149968/ENSG00000176697/ENSG00000146674/ENSG00000150782/ENSG00000100234/ENSG00000069702 26 ENSG00000125347/ENSG00000165949/ENSG00000115415/ENSG00000090339/ENSG00000115267/ENSG00000271503/ENSG00000094804/ENSG00000136244/ENSG00000055332/ENSG00000151882/ENSG00000169248/ENSG00000120949/ENSG00000169429/ENSG00000006210/ENSG00000184371/ENSG00000197249/ENSG00000163661/ENSG00000232810/ENSG00000157873/ENSG00000102962/ENSG00000206073/ENSG00000160255/ENSG00000137462/ENSG00000145147/ENSG00000163131/ENSG00000115232 DOID:865 vasculitis 12/268 88/6421 0.000263294639736311 0.00405963595686452 ENSG00000234745/ENSG00000125347/ENSG00000108679/ENSG00000090339/ENSG00000136244/ENSG00000157601/ENSG00000169429/ENSG00000197249/ENSG00000232810/ENSG00000164136/ENSG00000138378/ENSG00000150782 HLA-B/IRF1/LGALS3BP/ICAM1/IL6/MX1/CXCL8/SERPINA1/TNF/IL15/STAT4/IL18 3106/3659/3959/3383/3569/4599/3576/5265/7124/3600/6775/3606 12 1 ENSG00000150782 11 ENSG00000234745/ENSG00000125347/ENSG00000108679/ENSG00000090339/ENSG00000136244/ENSG00000157601/ENSG00000169429/ENSG00000197249/ENSG00000232810/ENSG00000164136/ENSG00000138378 DOID:0050589 inflammatory bowel disease 11/268 76/6421 0.000279008514056706 0.00420415101862718 ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000131196/ENSG00000023445/ENSG00000169429/ENSG00000149968/ENSG00000160255/ENSG00000104267/ENSG00000135480/ENSG00000150782 ICAM1/CCL5/IL6/NFATC1/BIRC3/CXCL8/MMP3/ITGB2/CA2/KRT7/IL18 3383/6352/3569/4772/330/3576/4314/3689/760/3855/3606 11 3 ENSG00000149968/ENSG00000104267/ENSG00000150782 8 ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000131196/ENSG00000023445/ENSG00000169429/ENSG00000160255/ENSG00000135480 DOID:15 reproductive system disease 25/268 285/6421 0.000314488779667559 0.00463346802043537 ENSG00000090339/ENSG00000139618/ENSG00000271503/ENSG00000136244/ENSG00000100918/ENSG00000006047/ENSG00000007038/ENSG00000163739/ENSG00000169429/ENSG00000006210/ENSG00000232810/ENSG00000101115/ENSG00000164136/ENSG00000164045/ENSG00000149968/ENSG00000183770/ENSG00000176697/ENSG00000146674/ENSG00000128342/ENSG00000137462/ENSG00000167034/ENSG00000150782/ENSG00000005073/ENSG00000115232/ENSG00000069702 ICAM1/BRCA2/CCL5/IL6/REC8/YBX2/PRSS21/CXCL1/CXCL8/CX3CL1/TNF/SALL4/IL15/CDC25A/MMP3/FOXL2/BDNF/IGFBP3/LIF/TLR2/NKX3-1/IL18/HOXA11/ITGA4/TGFBR3 3383/675/6352/3569/9985/51087/10942/2919/3576/6376/7124/57167/3600/993/4314/668/627/3486/3976/7097/4824/3606/3207/3676/7049 25 6 ENSG00000149968/ENSG00000183770/ENSG00000176697/ENSG00000146674/ENSG00000150782/ENSG00000069702 19 ENSG00000090339/ENSG00000139618/ENSG00000271503/ENSG00000136244/ENSG00000100918/ENSG00000006047/ENSG00000007038/ENSG00000163739/ENSG00000169429/ENSG00000006210/ENSG00000232810/ENSG00000101115/ENSG00000164136/ENSG00000164045/ENSG00000128342/ENSG00000137462/ENSG00000167034/ENSG00000005073/ENSG00000115232 DOID:2043 hepatitis B 17/268 162/6421 0.000389970941115479 0.00562066812955571 ENSG00000115415/ENSG00000204525/ENSG00000089127/ENSG00000271503/ENSG00000136244/ENSG00000055332/ENSG00000157601/ENSG00000179750/ENSG00000213928/ENSG00000240065/ENSG00000232810/ENSG00000149968/ENSG00000239713/ENSG00000206073/ENSG00000137462/ENSG00000150782/ENSG00000044574 STAT1/HLA-C/OAS1/CCL5/IL6/EIF2AK2/MX1/APOBEC3B/IRF9/PSMB9/TNF/MMP3/APOBEC3G/SERPINB4/TLR2/IL18/HSPA5 6772/3107/4938/6352/3569/5610/4599/9582/10379/5698/7124/4314/60489/6318/7097/3606/3309 17 2 ENSG00000149968/ENSG00000150782 15 ENSG00000115415/ENSG00000204525/ENSG00000089127/ENSG00000271503/ENSG00000136244/ENSG00000055332/ENSG00000157601/ENSG00000179750/ENSG00000213928/ENSG00000240065/ENSG00000232810/ENSG00000239713/ENSG00000206073/ENSG00000137462/ENSG00000044574 DOID:1483 gingival disease 6/268 25/6421 0.000452548942765258 0.00605370070416033 ENSG00000136244/ENSG00000131196/ENSG00000164136/ENSG00000149968/ENSG00000137462/ENSG00000150782 IL6/NFATC1/IL15/MMP3/TLR2/IL18 3569/4772/3600/4314/7097/3606 6 2 ENSG00000149968/ENSG00000150782 4 ENSG00000136244/ENSG00000131196/ENSG00000164136/ENSG00000137462 DOID:10871 age related macular degeneration 9/268 56/6421 0.000453691686280054 0.00605370070416033 ENSG00000234745/ENSG00000090339/ENSG00000149131/ENSG00000000971/ENSG00000232810/ENSG00000166033/ENSG00000243649/ENSG00000184792/ENSG00000100234 HLA-B/ICAM1/SERPING1/CFH/TNF/HTRA1/CFB/OSBP2/TIMP3 3106/3383/710/3075/7124/5654/629/23762/7078 9 2 ENSG00000166033/ENSG00000100234 7 ENSG00000234745/ENSG00000090339/ENSG00000149131/ENSG00000000971/ENSG00000232810/ENSG00000243649/ENSG00000184792 DOID:2007 degeneration of macula and posterior pole 9/268 56/6421 0.000453691686280054 0.00605370070416033 ENSG00000234745/ENSG00000090339/ENSG00000149131/ENSG00000000971/ENSG00000232810/ENSG00000166033/ENSG00000243649/ENSG00000184792/ENSG00000100234 HLA-B/ICAM1/SERPING1/CFH/TNF/HTRA1/CFB/OSBP2/TIMP3 3106/3383/710/3075/7124/5654/629/23762/7078 9 2 ENSG00000166033/ENSG00000100234 7 ENSG00000234745/ENSG00000090339/ENSG00000149131/ENSG00000000971/ENSG00000232810/ENSG00000243649/ENSG00000184792 DOID:6590 spondylitis 8/268 45/6421 0.00046566928493541 0.00605370070416033 ENSG00000234745/ENSG00000204525/ENSG00000136244/ENSG00000164308/ENSG00000232810/ENSG00000149968/ENSG00000150782/ENSG00000044574 HLA-B/HLA-C/IL6/ERAP2/TNF/MMP3/IL18/HSPA5 3106/3107/3569/64167/7124/4314/3606/3309 8 2 ENSG00000149968/ENSG00000150782 6 ENSG00000234745/ENSG00000204525/ENSG00000136244/ENSG00000164308/ENSG00000232810/ENSG00000044574 DOID:7147 ankylosing spondylitis 8/268 45/6421 0.00046566928493541 0.00605370070416033 ENSG00000234745/ENSG00000204525/ENSG00000136244/ENSG00000164308/ENSG00000232810/ENSG00000149968/ENSG00000150782/ENSG00000044574 HLA-B/HLA-C/IL6/ERAP2/TNF/MMP3/IL18/HSPA5 3106/3107/3569/64167/7124/4314/3606/3309 8 2 ENSG00000149968/ENSG00000150782 6 ENSG00000234745/ENSG00000204525/ENSG00000136244/ENSG00000164308/ENSG00000232810/ENSG00000044574 DOID:3952 adrenal cortex disease 7/268 35/6421 0.000501843683554431 0.006398506965319 ENSG00000115267/ENSG00000158050/ENSG00000170430/ENSG00000136244/ENSG00000117594/ENSG00000169429/ENSG00000150782 IFIH1/DUSP2/MGMT/IL6/HSD11B1/CXCL8/IL18 64135/1844/4255/3569/3290/3576/3606 7 1 ENSG00000150782 6 ENSG00000115267/ENSG00000158050/ENSG00000170430/ENSG00000136244/ENSG00000117594/ENSG00000169429 DOID:12361 Graves' disease 9/268 57/6421 0.000519450013923597 0.0064005771271612 ENSG00000234745/ENSG00000125347/ENSG00000204525/ENSG00000090339/ENSG00000115267/ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000232810 HLA-B/IRF1/HLA-C/ICAM1/IFIH1/CCL5/IL6/CXCL8/TNF 3106/3659/3107/3383/64135/6352/3569/3576/7124 9 0 9 ENSG00000234745/ENSG00000125347/ENSG00000204525/ENSG00000090339/ENSG00000115267/ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000232810 DOID:4481 allergic rhinitis 10/268 69/6421 0.000521313974157926 0.0064005771271612 ENSG00000234745/ENSG00000204525/ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000006210/ENSG00000232810/ENSG00000137462/ENSG00000150782 HLA-B/HLA-C/ICAM1/CCL5/IL6/CXCL8/CX3CL1/TNF/TLR2/IL18 3106/3107/3383/6352/3569/3576/6376/7124/7097/3606 10 1 ENSG00000150782 9 ENSG00000234745/ENSG00000204525/ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000006210/ENSG00000232810/ENSG00000137462 DOID:10923 sickle cell anemia 6/268 26/6421 0.000567981445351315 0.00684675815032585 ENSG00000090339/ENSG00000232810/ENSG00000146674/ENSG00000150782/ENSG00000241635/ENSG00000115232 ICAM1/TNF/IGFBP3/IL18/UGT1A1/ITGA4 3383/7124/3486/3606/54658/3676 6 2 ENSG00000146674/ENSG00000150782 4 ENSG00000090339/ENSG00000232810/ENSG00000241635/ENSG00000115232 DOID:4448 macular degeneration 9/268 58/6421 0.000592831251641621 0.00699187784012509 ENSG00000234745/ENSG00000090339/ENSG00000149131/ENSG00000000971/ENSG00000232810/ENSG00000166033/ENSG00000243649/ENSG00000184792/ENSG00000100234 HLA-B/ICAM1/SERPING1/CFH/TNF/HTRA1/CFB/OSBP2/TIMP3 3106/3383/710/3075/7124/5654/629/23762/7078 9 2 ENSG00000166033/ENSG00000100234 7 ENSG00000234745/ENSG00000090339/ENSG00000149131/ENSG00000000971/ENSG00000232810/ENSG00000243649/ENSG00000184792 DOID:9553 adrenal gland disease 7/268 36/6421 0.000601111669513017 0.00699187784012509 ENSG00000115267/ENSG00000158050/ENSG00000170430/ENSG00000136244/ENSG00000117594/ENSG00000169429/ENSG00000150782 IFIH1/DUSP2/MGMT/IL6/HSD11B1/CXCL8/IL18 64135/1844/4255/3569/3290/3576/3606 7 1 ENSG00000150782 6 ENSG00000115267/ENSG00000158050/ENSG00000170430/ENSG00000136244/ENSG00000117594/ENSG00000169429 DOID:2163 nasal cavity disease 10/268 71/6421 0.000657758049011417 0.00726822644157616 ENSG00000234745/ENSG00000204525/ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000006210/ENSG00000232810/ENSG00000137462/ENSG00000150782 HLA-B/HLA-C/ICAM1/CCL5/IL6/CXCL8/CX3CL1/TNF/TLR2/IL18 3106/3107/3383/6352/3569/3576/6376/7124/7097/3606 10 1 ENSG00000150782 9 ENSG00000234745/ENSG00000204525/ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000006210/ENSG00000232810/ENSG00000137462 DOID:2825 nose disease 10/268 71/6421 0.000657758049011417 0.00726822644157616 ENSG00000234745/ENSG00000204525/ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000006210/ENSG00000232810/ENSG00000137462/ENSG00000150782 HLA-B/HLA-C/ICAM1/CCL5/IL6/CXCL8/CX3CL1/TNF/TLR2/IL18 3106/3107/3383/6352/3569/3576/6376/7124/7097/3606 10 1 ENSG00000150782 9 ENSG00000234745/ENSG00000204525/ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000006210/ENSG00000232810/ENSG00000137462 DOID:4483 rhinitis 10/268 71/6421 0.000657758049011417 0.00726822644157616 ENSG00000234745/ENSG00000204525/ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000006210/ENSG00000232810/ENSG00000137462/ENSG00000150782 HLA-B/HLA-C/ICAM1/CCL5/IL6/CXCL8/CX3CL1/TNF/TLR2/IL18 3106/3107/3383/6352/3569/3576/6376/7124/7097/3606 10 1 ENSG00000150782 9 ENSG00000234745/ENSG00000204525/ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000006210/ENSG00000232810/ENSG00000137462 DOID:13241 Behcet's disease 9/268 59/6421 0.000674488665917236 0.00733091779513324 ENSG00000234745/ENSG00000125347/ENSG00000108679/ENSG00000090339/ENSG00000169429/ENSG00000232810/ENSG00000164136/ENSG00000138378/ENSG00000150782 HLA-B/IRF1/LGALS3BP/ICAM1/CXCL8/TNF/IL15/STAT4/IL18 3106/3659/3959/3383/3576/7124/3600/6775/3606 9 1 ENSG00000150782 8 ENSG00000234745/ENSG00000125347/ENSG00000108679/ENSG00000090339/ENSG00000169429/ENSG00000232810/ENSG00000164136/ENSG00000138378 DOID:403 mouth disease 15/268 140/6421 0.000686149794542543 0.00733737602873719 ENSG00000234745/ENSG00000271503/ENSG00000162892/ENSG00000136244/ENSG00000160710/ENSG00000131196/ENSG00000169429/ENSG00000184371/ENSG00000115009/ENSG00000232810/ENSG00000164136/ENSG00000149968/ENSG00000008517/ENSG00000137462/ENSG00000150782 HLA-B/CCL5/IL24/IL6/ADAR/NFATC1/CXCL8/CSF1/CCL20/TNF/IL15/MMP3/IL32/TLR2/IL18 3106/6352/11009/3569/103/4772/3576/1435/6364/7124/3600/4314/9235/7097/3606 15 2 ENSG00000149968/ENSG00000150782 13 ENSG00000234745/ENSG00000271503/ENSG00000162892/ENSG00000136244/ENSG00000160710/ENSG00000131196/ENSG00000169429/ENSG00000184371/ENSG00000115009/ENSG00000232810/ENSG00000164136/ENSG00000008517/ENSG00000137462 DOID:8398 osteoarthritis 16/268 156/6421 0.000742865057013978 0.00781777036190901 ENSG00000166710/ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000049089/ENSG00000132031/ENSG00000115009/ENSG00000232810/ENSG00000166033/ENSG00000149968/ENSG00000196562/ENSG00000160255/ENSG00000163131/ENSG00000123610/ENSG00000044574/ENSG00000069702 B2M/CCL5/IL6/CXCL8/COL9A2/MATN3/CCL20/TNF/HTRA1/MMP3/SULF2/ITGB2/CTSS/TNFAIP6/HSPA5/TGFBR3 567/6352/3569/3576/1298/4148/6364/7124/5654/4314/55959/3689/1520/7130/3309/7049 16 4 ENSG00000166033/ENSG00000149968/ENSG00000196562/ENSG00000069702 12 ENSG00000166710/ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000049089/ENSG00000132031/ENSG00000115009/ENSG00000232810/ENSG00000160255/ENSG00000163131/ENSG00000123610/ENSG00000044574 DOID:0060005 autoimmune disease of endocrine system 9/268 60/6421 0.00076510931412911 0.00792605430105625 ENSG00000234745/ENSG00000125347/ENSG00000204525/ENSG00000090339/ENSG00000115267/ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000232810 HLA-B/IRF1/HLA-C/ICAM1/IFIH1/CCL5/IL6/CXCL8/TNF 3106/3659/3107/3383/64135/6352/3569/3576/7124 9 0 9 ENSG00000234745/ENSG00000125347/ENSG00000204525/ENSG00000090339/ENSG00000115267/ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000232810 DOID:974 upper respiratory tract disease 11/268 86/6421 0.000823573124245216 0.00840044586730121 ENSG00000234745/ENSG00000204525/ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000076706/ENSG00000169429/ENSG00000006210/ENSG00000232810/ENSG00000137462/ENSG00000150782 HLA-B/HLA-C/ICAM1/CCL5/IL6/MCAM/CXCL8/CX3CL1/TNF/TLR2/IL18 3106/3107/3383/6352/3569/4162/3576/6376/7124/7097/3606 11 1 ENSG00000150782 10 ENSG00000234745/ENSG00000204525/ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000076706/ENSG00000169429/ENSG00000006210/ENSG00000232810/ENSG00000137462 DOID:4798 aggressive systemic mastocytosis 5/268 19/6421 0.000875977817622432 0.00879959534975261 ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000176697/ENSG00000101412 CCL5/IL6/CXCL8/BDNF/E2F1 6352/3569/3576/627/1869 5 1 ENSG00000176697 4 ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000101412 DOID:824 periodontitis 11/268 87/6421 0.000908616080793712 0.00899123076964524 ENSG00000234745/ENSG00000271503/ENSG00000162892/ENSG00000136244/ENSG00000131196/ENSG00000169429/ENSG00000184371/ENSG00000232810/ENSG00000149968/ENSG00000137462/ENSG00000150782 HLA-B/CCL5/IL24/IL6/NFATC1/CXCL8/CSF1/TNF/MMP3/TLR2/IL18 3106/6352/11009/3569/4772/3576/1435/7124/4314/7097/3606 11 2 ENSG00000149968/ENSG00000150782 9 ENSG00000234745/ENSG00000271503/ENSG00000162892/ENSG00000136244/ENSG00000131196/ENSG00000169429/ENSG00000184371/ENSG00000232810/ENSG00000137462 DOID:1091 tooth disease 13/268 116/6421 0.00101873814855446 0.00979712304343861 ENSG00000234745/ENSG00000271503/ENSG00000162892/ENSG00000136244/ENSG00000131196/ENSG00000169429/ENSG00000184371/ENSG00000115009/ENSG00000232810/ENSG00000164136/ENSG00000149968/ENSG00000137462/ENSG00000150782 HLA-B/CCL5/IL24/IL6/NFATC1/CXCL8/CSF1/CCL20/TNF/IL15/MMP3/TLR2/IL18 3106/6352/11009/3569/4772/3576/1435/6364/7124/3600/4314/7097/3606 13 2 ENSG00000149968/ENSG00000150782 11 ENSG00000234745/ENSG00000271503/ENSG00000162892/ENSG00000136244/ENSG00000131196/ENSG00000169429/ENSG00000184371/ENSG00000115009/ENSG00000232810/ENSG00000164136/ENSG00000137462 DOID:12365 malaria 10/268 75/6421 0.00101961009049361 0.00979712304343861 ENSG00000234745/ENSG00000125347/ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000006210/ENSG00000232810/ENSG00000185339/ENSG00000137462/ENSG00000150782 HLA-B/IRF1/ICAM1/CCL5/IL6/CX3CL1/TNF/TCN2/TLR2/IL18 3106/3659/3383/6352/3569/6376/7124/6948/7097/3606 10 1 ENSG00000150782 9 ENSG00000234745/ENSG00000125347/ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000006210/ENSG00000232810/ENSG00000185339/ENSG00000137462 DOID:229 female reproductive system disease 15/268 146/6421 0.00106322750144808 0.00984548448245931 ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000163739/ENSG00000169429/ENSG00000232810/ENSG00000101115/ENSG00000164136/ENSG00000149968/ENSG00000183770/ENSG00000146674/ENSG00000128342/ENSG00000137462/ENSG00000150782/ENSG00000069702 ICAM1/CCL5/IL6/CXCL1/CXCL8/TNF/SALL4/IL15/MMP3/FOXL2/IGFBP3/LIF/TLR2/IL18/TGFBR3 3383/6352/3569/2919/3576/7124/57167/3600/4314/668/3486/3976/7097/3606/7049 15 5 ENSG00000149968/ENSG00000183770/ENSG00000146674/ENSG00000150782/ENSG00000069702 10 ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000163739/ENSG00000169429/ENSG00000232810/ENSG00000101115/ENSG00000164136/ENSG00000128342/ENSG00000137462 DOID:417 hypersensitivity reaction type II disease 33/268 453/6421 0.0010758150302302 0.00984548448245931 ENSG00000234745/ENSG00000125347/ENSG00000115415/ENSG00000204525/ENSG00000090339/ENSG00000115267/ENSG00000079385/ENSG00000271503/ENSG00000136244/ENSG00000160710/ENSG00000157601/ENSG00000168685/ENSG00000132109/ENSG00000141682/ENSG00000240065/ENSG00000169429/ENSG00000006210/ENSG00000204264/ENSG00000197646/ENSG00000000971/ENSG00000197249/ENSG00000163661/ENSG00000232810/ENSG00000167165/ENSG00000164136/ENSG00000102962/ENSG00000176697/ENSG00000146674/ENSG00000138378/ENSG00000137462/ENSG00000115163/ENSG00000150782/ENSG00000107165 HLA-B/IRF1/STAT1/HLA-C/ICAM1/IFIH1/CEACAM1/CCL5/IL6/ADAR/MX1/IL7R/TRIM21/PMAIP1/PSMB9/CXCL8/CX3CL1/PSMB8/PDCD1LG2/CFH/SERPINA1/PTX3/TNF/UGT1A6/IL15/CCL22/BDNF/IGFBP3/STAT4/TLR2/CENPA/IL18/TYRP1 3106/3659/6772/3107/3383/64135/634/6352/3569/103/4599/3575/6737/5366/5698/3576/6376/5696/80380/3075/5265/5806/7124/54578/3600/6367/627/3486/6775/7097/1058/3606/7306 33 3 ENSG00000176697/ENSG00000146674/ENSG00000150782 30 ENSG00000234745/ENSG00000125347/ENSG00000115415/ENSG00000204525/ENSG00000090339/ENSG00000115267/ENSG00000079385/ENSG00000271503/ENSG00000136244/ENSG00000160710/ENSG00000157601/ENSG00000168685/ENSG00000132109/ENSG00000141682/ENSG00000240065/ENSG00000169429/ENSG00000006210/ENSG00000204264/ENSG00000197646/ENSG00000000971/ENSG00000197249/ENSG00000163661/ENSG00000232810/ENSG00000167165/ENSG00000164136/ENSG00000102962/ENSG00000138378/ENSG00000137462/ENSG00000115163/ENSG00000107165 DOID:12140 Chagas disease 4/268 12/6421 0.00112627028569456 0.00984548448245931 ENSG00000136244/ENSG00000232810/ENSG00000164136/ENSG00000137462 IL6/TNF/IL15/TLR2 3569/7124/3600/7097 4 0 4 ENSG00000136244/ENSG00000232810/ENSG00000164136/ENSG00000137462 DOID:1969 cerebral palsy 4/268 12/6421 0.00112627028569456 0.00984548448245931 ENSG00000136244/ENSG00000169429/ENSG00000146674/ENSG00000150782 IL6/CXCL8/IGFBP3/IL18 3569/3576/3486/3606 4 2 ENSG00000146674/ENSG00000150782 2 ENSG00000136244/ENSG00000169429 DOID:2978 carbohydrate metabolic disorder 5/268 20/6421 0.00112859248969368 0.00984548448245931 ENSG00000174607/ENSG00000136244/ENSG00000169429/ENSG00000184185/ENSG00000069702 UGT8/IL6/CXCL8/KCNJ12/TGFBR3 7368/3569/3576/3768/7049 5 1 ENSG00000069702 4 ENSG00000174607/ENSG00000136244/ENSG00000169429/ENSG00000184185 DOID:9446 cholangitis 5/268 20/6421 0.00112859248969368 0.00984548448245931 ENSG00000204525/ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000137462 HLA-C/ICAM1/CCL5/IL6/TLR2 3107/3383/6352/3569/7097 5 0 5 ENSG00000204525/ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000137462 DOID:9471 meningitis 5/268 20/6421 0.00112859248969368 0.00984548448245931 ENSG00000090339/ENSG00000169429/ENSG00000117228/ENSG00000111674/ENSG00000137462 ICAM1/CXCL8/GBP1/ENO2/TLR2 3383/3576/2633/2026/7097 5 0 5 ENSG00000090339/ENSG00000169429/ENSG00000117228/ENSG00000111674/ENSG00000137462 DOID:2355 anemia 18/268 195/6421 0.00122884378150787 0.0105808237290872 ENSG00000234745/ENSG00000090339/ENSG00000139618/ENSG00000271503/ENSG00000136244/ENSG00000055332/ENSG00000169429/ENSG00000006210/ENSG00000000971/ENSG00000232810/ENSG00000243649/ENSG00000164136/ENSG00000146674/ENSG00000185339/ENSG00000104267/ENSG00000150782/ENSG00000241635/ENSG00000197299 HLA-B/ICAM1/BRCA2/CCL5/IL6/EIF2AK2/CXCL8/CX3CL1/CFH/TNF/CFB/IL15/IGFBP3/TCN2/CA2/IL18/UGT1A1/BLM 3106/3383/675/6352/3569/5610/3576/6376/3075/7124/629/3600/3486/6948/760/3606/54658/641 18 3 ENSG00000146674/ENSG00000104267/ENSG00000150782 15 ENSG00000234745/ENSG00000090339/ENSG00000139618/ENSG00000271503/ENSG00000136244/ENSG00000055332/ENSG00000169429/ENSG00000006210/ENSG00000000971/ENSG00000232810/ENSG00000243649/ENSG00000164136/ENSG00000185339/ENSG00000241635/ENSG00000197299 DOID:3947 adrenal gland hyperfunction 5/268 21/6421 0.00143138675175689 0.0120196389533029 ENSG00000158050/ENSG00000136244/ENSG00000117594/ENSG00000169429/ENSG00000150782 DUSP2/IL6/HSD11B1/CXCL8/IL18 1844/3569/3290/3576/3606 5 1 ENSG00000150782 4 ENSG00000158050/ENSG00000136244/ENSG00000117594/ENSG00000169429 DOID:10591 pre-eclampsia 19/268 214/6421 0.00143896784122743 0.0120196389533029 ENSG00000090339/ENSG00000136244/ENSG00000120949/ENSG00000173391/ENSG00000169429/ENSG00000184371/ENSG00000038427/ENSG00000164308/ENSG00000000971/ENSG00000163661/ENSG00000232810/ENSG00000166033/ENSG00000164136/ENSG00000128342/ENSG00000137462/ENSG00000135636/ENSG00000129757/ENSG00000150782/ENSG00000044574 ICAM1/IL6/TNFRSF8/OLR1/CXCL8/CSF1/VCAN/ERAP2/CFH/PTX3/TNF/HTRA1/IL15/LIF/TLR2/DYSF/CDKN1C/IL18/HSPA5 3383/3569/943/4973/3576/1435/1462/64167/3075/5806/7124/5654/3600/3976/7097/8291/1028/3606/3309 19 3 ENSG00000038427/ENSG00000166033/ENSG00000150782 16 ENSG00000090339/ENSG00000136244/ENSG00000120949/ENSG00000173391/ENSG00000169429/ENSG00000184371/ENSG00000164308/ENSG00000000971/ENSG00000163661/ENSG00000232810/ENSG00000164136/ENSG00000128342/ENSG00000137462/ENSG00000135636/ENSG00000129757/ENSG00000044574 DOID:2789 parasitic protozoa infectious disease 11/268 92/6421 0.00145033350869417 0.0120196389533029 ENSG00000234745/ENSG00000125347/ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000006210/ENSG00000232810/ENSG00000164136/ENSG00000185339/ENSG00000137462/ENSG00000150782 HLA-B/IRF1/ICAM1/CCL5/IL6/CX3CL1/TNF/IL15/TCN2/TLR2/IL18 3106/3659/3383/6352/3569/6376/7124/3600/6948/7097/3606 11 1 ENSG00000150782 10 ENSG00000234745/ENSG00000125347/ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000006210/ENSG00000232810/ENSG00000164136/ENSG00000185339/ENSG00000137462 DOID:8778 Crohn's disease 7/268 42/6421 0.00156853307685918 0.0125719228771126 ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000149968/ENSG00000160255/ENSG00000150782 ICAM1/CCL5/IL6/CXCL8/MMP3/ITGB2/IL18 3383/6352/3569/3576/4314/3689/3606 7 2 ENSG00000149968/ENSG00000150782 5 ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000160255 DOID:10113 trypanosomiasis 4/268 13/6421 0.00157386063167473 0.0125719228771126 ENSG00000136244/ENSG00000232810/ENSG00000164136/ENSG00000137462 IL6/TNF/IL15/TLR2 3569/7124/3600/7097 4 0 4 ENSG00000136244/ENSG00000232810/ENSG00000164136/ENSG00000137462 DOID:1273 respiratory syncytial virus infectious disease 4/268 13/6421 0.00157386063167473 0.0125719228771126 ENSG00000089127/ENSG00000271503/ENSG00000169429/ENSG00000150782 OAS1/CCL5/CXCL8/IL18 4938/6352/3576/3606 4 1 ENSG00000150782 3 ENSG00000089127/ENSG00000271503/ENSG00000169429 DOID:1588 thrombocytopenia 8/268 55/6421 0.00183353263831678 0.0144718111810003 ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000000971/ENSG00000160255/ENSG00000129757/ENSG00000150782 ICAM1/CCL5/IL6/CXCL8/CFH/ITGB2/CDKN1C/IL18 3383/6352/3569/3576/3075/3689/1028/3606 8 1 ENSG00000150782 7 ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000000971/ENSG00000160255/ENSG00000129757 DOID:7998 hyperthyroidism 9/268 68/6421 0.00190633784922642 0.0146965348143851 ENSG00000234745/ENSG00000125347/ENSG00000204525/ENSG00000090339/ENSG00000115267/ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000232810 HLA-B/IRF1/HLA-C/ICAM1/IFIH1/CCL5/IL6/CXCL8/TNF 3106/3659/3107/3383/64135/6352/3569/3576/7124 9 0 9 ENSG00000234745/ENSG00000125347/ENSG00000204525/ENSG00000090339/ENSG00000115267/ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000232810 DOID:9500 leukocyte disease 9/268 68/6421 0.00190633784922642 0.0146965348143851 ENSG00000271503/ENSG00000136244/ENSG00000023445/ENSG00000169429/ENSG00000232810/ENSG00000164136/ENSG00000176697/ENSG00000101412/ENSG00000241635 CCL5/IL6/BIRC3/CXCL8/TNF/IL15/BDNF/E2F1/UGT1A1 6352/3569/330/3576/7124/3600/627/1869/54658 9 1 ENSG00000176697 8 ENSG00000271503/ENSG00000136244/ENSG00000023445/ENSG00000169429/ENSG00000232810/ENSG00000164136/ENSG00000101412/ENSG00000241635 DOID:5679 retinal disease 23/268 289/6421 0.00205283103952465 0.0156439882667223 ENSG00000234745/ENSG00000090339/ENSG00000271503/ENSG00000171812/ENSG00000136244/ENSG00000149131/ENSG00000169429/ENSG00000174804/ENSG00000000971/ENSG00000232810/ENSG00000166033/ENSG00000243649/ENSG00000149968/ENSG00000111674/ENSG00000176697/ENSG00000146674/ENSG00000144810/ENSG00000184792/ENSG00000148600/ENSG00000137462/ENSG00000107165/ENSG00000044574/ENSG00000100234 HLA-B/ICAM1/CCL5/COL8A2/IL6/SERPING1/CXCL8/FZD4/CFH/TNF/HTRA1/CFB/MMP3/ENO2/BDNF/IGFBP3/COL8A1/OSBP2/CDHR1/TLR2/TYRP1/HSPA5/TIMP3 3106/3383/6352/1296/3569/710/3576/8322/3075/7124/5654/629/4314/2026/627/3486/1295/23762/92211/7097/7306/3309/7078 23 6 ENSG00000166033/ENSG00000149968/ENSG00000176697/ENSG00000146674/ENSG00000148600/ENSG00000100234 17 ENSG00000234745/ENSG00000090339/ENSG00000271503/ENSG00000171812/ENSG00000136244/ENSG00000149131/ENSG00000169429/ENSG00000174804/ENSG00000000971/ENSG00000232810/ENSG00000243649/ENSG00000111674/ENSG00000144810/ENSG00000184792/ENSG00000137462/ENSG00000107165/ENSG00000044574 DOID:84 osteochondritis dissecans 4/268 14/6421 0.00213175601422979 0.0159247080322659 ENSG00000232810/ENSG00000149968/ENSG00000176697/ENSG00000135312 TNF/MMP3/BDNF/HTR1B 7124/4314/627/3351 4 2 ENSG00000149968/ENSG00000176697 2 ENSG00000232810/ENSG00000135312 DOID:3480 uveal disease 6/268 33/6421 0.00213770590478381 0.0159247080322659 ENSG00000090339/ENSG00000000971/ENSG00000197249/ENSG00000232810/ENSG00000149968/ENSG00000137462 ICAM1/CFH/SERPINA1/TNF/MMP3/TLR2 3383/3075/5265/7124/4314/7097 6 1 ENSG00000149968 5 ENSG00000090339/ENSG00000000971/ENSG00000197249/ENSG00000232810/ENSG00000137462 DOID:12894 Sjogren's syndrome 8/268 57/6421 0.00231559692483708 0.0170582306796331 ENSG00000115415/ENSG00000090339/ENSG00000132109/ENSG00000240065/ENSG00000232810/ENSG00000176697/ENSG00000138378/ENSG00000150782 STAT1/ICAM1/TRIM21/PSMB9/TNF/BDNF/STAT4/IL18 6772/3383/6737/5698/7124/627/6775/3606 8 2 ENSG00000176697/ENSG00000150782 6 ENSG00000115415/ENSG00000090339/ENSG00000132109/ENSG00000240065/ENSG00000232810/ENSG00000138378 DOID:1398 parasitic infectious disease 12/268 113/6421 0.00250786399365042 0.0182715805251674 ENSG00000234745/ENSG00000125347/ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000006210/ENSG00000232810/ENSG00000164136/ENSG00000185339/ENSG00000206073/ENSG00000137462/ENSG00000150782 HLA-B/IRF1/ICAM1/CCL5/IL6/CX3CL1/TNF/IL15/TCN2/SERPINB4/TLR2/IL18 3106/3659/3383/6352/3569/6376/7124/3600/6948/6318/7097/3606 12 1 ENSG00000150782 11 ENSG00000234745/ENSG00000125347/ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000006210/ENSG00000232810/ENSG00000164136/ENSG00000185339/ENSG00000206073/ENSG00000137462 DOID:10223 dermatomyositis 5/268 24/6421 0.00269834753300229 0.019257119164333 ENSG00000115267/ENSG00000136244/ENSG00000232810/ENSG00000164136/ENSG00000137462 IFIH1/IL6/TNF/IL15/TLR2 64135/3569/7124/3600/7097 5 0 5 ENSG00000115267/ENSG00000136244/ENSG00000232810/ENSG00000164136/ENSG00000137462 DOID:10952 nephritis 12/268 114/6421 0.0027012248601553 0.019257119164333 ENSG00000107201/ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000184371/ENSG00000000971/ENSG00000100342/ENSG00000163661/ENSG00000232810/ENSG00000146674/ENSG00000162891/ENSG00000150782 DDX58/ICAM1/CCL5/IL6/CSF1/CFH/APOL1/PTX3/TNF/IGFBP3/IL20/IL18 23586/3383/6352/3569/1435/3075/8542/5806/7124/3486/50604/3606 12 2 ENSG00000146674/ENSG00000150782 10 ENSG00000107201/ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000184371/ENSG00000000971/ENSG00000100342/ENSG00000163661/ENSG00000232810/ENSG00000162891 DOID:11729 Lyme disease 4/268 15/6421 0.00281254717575056 0.0196286187107645 ENSG00000136244/ENSG00000169248/ENSG00000111674/ENSG00000137462 IL6/CXCL11/ENO2/TLR2 3569/6373/2026/7097 4 0 4 ENSG00000136244/ENSG00000169248/ENSG00000111674/ENSG00000137462 DOID:12252 Cushing's syndrome 4/268 15/6421 0.00281254717575056 0.0196286187107645 ENSG00000136244/ENSG00000117594/ENSG00000169429/ENSG00000150782 IL6/HSD11B1/CXCL8/IL18 3569/3290/3576/3606 4 1 ENSG00000150782 3 ENSG00000136244/ENSG00000117594/ENSG00000169429 DOID:289 endometriosis 9/268 72/6421 0.00284753812683472 0.0196658101884523 ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000164136/ENSG00000149968/ENSG00000146674/ENSG00000128342/ENSG00000150782 ICAM1/CCL5/IL6/CXCL8/IL15/MMP3/IGFBP3/LIF/IL18 3383/6352/3569/3576/3600/4314/3486/3976/3606 9 3 ENSG00000149968/ENSG00000146674/ENSG00000150782 6 ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000164136/ENSG00000128342 DOID:1485 cystic fibrosis 12/268 115/6421 0.00290654924586204 0.0198664139175931 ENSG00000115415/ENSG00000090339/ENSG00000154277/ENSG00000136244/ENSG00000169429/ENSG00000197249/ENSG00000163661/ENSG00000232810/ENSG00000146674/ENSG00000137462/ENSG00000150782/ENSG00000016602 STAT1/ICAM1/UCHL1/IL6/CXCL8/SERPINA1/PTX3/TNF/IGFBP3/TLR2/IL18/CLCA4 6772/3383/7345/3569/3576/5265/5806/7124/3486/7097/3606/22802 12 3 ENSG00000146674/ENSG00000150782/ENSG00000016602 9 ENSG00000115415/ENSG00000090339/ENSG00000154277/ENSG00000136244/ENSG00000169429/ENSG00000197249/ENSG00000163661/ENSG00000232810/ENSG00000137462 DOID:4029 gastritis 7/268 47/6421 0.00306133437930661 0.0207108642191866 ENSG00000166710/ENSG00000170430/ENSG00000169429/ENSG00000115009/ENSG00000232810/ENSG00000240563/ENSG00000137462 B2M/MGMT/CXCL8/CCL20/TNF/L1TD1/TLR2 567/4255/3576/6364/7124/54596/7097 7 0 7 ENSG00000166710/ENSG00000170430/ENSG00000169429/ENSG00000115009/ENSG00000232810/ENSG00000240563/ENSG00000137462 DOID:0060031 autoimmune disease of gastrointestinal tract 9/268 73/6421 0.00313231830490826 0.0209241873319025 ENSG00000234745/ENSG00000125347/ENSG00000115415/ENSG00000090339/ENSG00000136244/ENSG00000169429/ENSG00000232810/ENSG00000167165/ENSG00000164136 HLA-B/IRF1/STAT1/ICAM1/IL6/CXCL8/TNF/UGT1A6/IL15 3106/3659/6772/3383/3569/3576/7124/54578/3600 9 0 9 ENSG00000234745/ENSG00000125347/ENSG00000115415/ENSG00000090339/ENSG00000136244/ENSG00000169429/ENSG00000232810/ENSG00000167165/ENSG00000164136 DOID:936 brain disease 26/268 353/6421 0.00316584012112611 0.0209241873319025 ENSG00000187608/ENSG00000234745/ENSG00000134321/ENSG00000115415/ENSG00000111331/ENSG00000111335/ENSG00000090339/ENSG00000136244/ENSG00000055332/ENSG00000159164/ENSG00000117594/ENSG00000169429/ENSG00000006210/ENSG00000163661/ENSG00000232810/ENSG00000171121/ENSG00000149968/ENSG00000111674/ENSG00000174482/ENSG00000176697/ENSG00000146674/ENSG00000008517/ENSG00000160255/ENSG00000196218/ENSG00000145147/ENSG00000150782 ISG15/HLA-B/RSAD2/STAT1/OAS3/OAS2/ICAM1/IL6/EIF2AK2/SV2A/HSD11B1/CXCL8/CX3CL1/PTX3/TNF/KCNMB3/MMP3/ENO2/LINGO2/BDNF/IGFBP3/IL32/ITGB2/RYR1/SLIT2/IL18 9636/3106/91543/6772/4940/4939/3383/3569/5610/9900/3290/3576/6376/5806/7124/27094/4314/2026/158038/627/3486/9235/3689/6261/9353/3606 26 4 ENSG00000149968/ENSG00000176697/ENSG00000146674/ENSG00000150782 22 ENSG00000187608/ENSG00000234745/ENSG00000134321/ENSG00000115415/ENSG00000111331/ENSG00000111335/ENSG00000090339/ENSG00000136244/ENSG00000055332/ENSG00000159164/ENSG00000117594/ENSG00000169429/ENSG00000006210/ENSG00000163661/ENSG00000232810/ENSG00000171121/ENSG00000111674/ENSG00000174482/ENSG00000008517/ENSG00000160255/ENSG00000196218/ENSG00000145147 DOID:0060180 colitis 8/268 60/6421 0.00321910574336961 0.0209241873319025 ENSG00000090339/ENSG00000136244/ENSG00000131196/ENSG00000023445/ENSG00000169429/ENSG00000149968/ENSG00000104267/ENSG00000135480 ICAM1/IL6/NFATC1/BIRC3/CXCL8/MMP3/CA2/KRT7 3383/3569/4772/330/3576/4314/760/3855 8 2 ENSG00000149968/ENSG00000104267 6 ENSG00000090339/ENSG00000136244/ENSG00000131196/ENSG00000023445/ENSG00000169429/ENSG00000135480 DOID:8577 ulcerative colitis 8/268 60/6421 0.00321910574336961 0.0209241873319025 ENSG00000090339/ENSG00000136244/ENSG00000131196/ENSG00000023445/ENSG00000169429/ENSG00000149968/ENSG00000104267/ENSG00000135480 ICAM1/IL6/NFATC1/BIRC3/CXCL8/MMP3/CA2/KRT7 3383/3569/4772/330/3576/4314/760/3855 8 2 ENSG00000149968/ENSG00000104267 6 ENSG00000090339/ENSG00000136244/ENSG00000131196/ENSG00000023445/ENSG00000169429/ENSG00000135480 DOID:5295 intestinal disease 13/268 132/6421 0.00329222786501337 0.0211917191699404 ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000131196/ENSG00000023445/ENSG00000185885/ENSG00000169429/ENSG00000164136/ENSG00000149968/ENSG00000160255/ENSG00000104267/ENSG00000135480/ENSG00000150782 ICAM1/CCL5/IL6/NFATC1/BIRC3/IFITM1/CXCL8/IL15/MMP3/ITGB2/CA2/KRT7/IL18 3383/6352/3569/4772/330/8519/3576/3600/4314/3689/760/3855/3606 13 3 ENSG00000149968/ENSG00000104267/ENSG00000150782 10 ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000131196/ENSG00000023445/ENSG00000185885/ENSG00000169429/ENSG00000164136/ENSG00000160255/ENSG00000135480 DOID:750 peptic ulcer disease 7/268 48/6421 0.00345912433517686 0.0220519176367525 ENSG00000136244/ENSG00000169429/ENSG00000232810/ENSG00000167165/ENSG00000149968/ENSG00000239713/ENSG00000137462 IL6/CXCL8/TNF/UGT1A6/MMP3/APOBEC3G/TLR2 3569/3576/7124/54578/4314/60489/7097 7 1 ENSG00000149968 6 ENSG00000136244/ENSG00000169429/ENSG00000232810/ENSG00000167165/ENSG00000239713/ENSG00000137462 DOID:3087 gingivitis 4/268 16/6421 0.00362846571190039 0.0229111692094282 ENSG00000136244/ENSG00000131196/ENSG00000137462/ENSG00000150782 IL6/NFATC1/TLR2/IL18 3569/4772/7097/3606 4 1 ENSG00000150782 3 ENSG00000136244/ENSG00000131196/ENSG00000137462 DOID:2462 retinal vascular disease 7/268 49/6421 0.00389512302792601 0.0234376520884613 ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000232810/ENSG00000176697/ENSG00000146674 ICAM1/CCL5/IL6/CXCL8/TNF/BDNF/IGFBP3 3383/6352/3569/3576/7124/627/3486 7 2 ENSG00000176697/ENSG00000146674 5 ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000232810 DOID:8947 diabetic retinopathy 7/268 49/6421 0.00389512302792601 0.0234376520884613 ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000232810/ENSG00000176697/ENSG00000146674 ICAM1/CCL5/IL6/CXCL8/TNF/BDNF/IGFBP3 3383/6352/3569/3576/7124/627/3486 7 2 ENSG00000176697/ENSG00000146674 5 ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000232810 DOID:13375 temporal arteritis 5/268 26/6421 0.00390070568894493 0.0234376520884613 ENSG00000090339/ENSG00000136244/ENSG00000157601/ENSG00000138378/ENSG00000150782 ICAM1/IL6/MX1/STAT4/IL18 3383/3569/4599/6775/3606 5 1 ENSG00000150782 4 ENSG00000090339/ENSG00000136244/ENSG00000157601/ENSG00000138378 DOID:319 spinal cord disease 5/268 26/6421 0.00390070568894493 0.0234376520884613 ENSG00000204525/ENSG00000100285/ENSG00000136244/ENSG00000169429/ENSG00000277586 HLA-C/NEFH/IL6/CXCL8/NEFL 3107/4744/3569/3576/4747 5 1 ENSG00000277586 4 ENSG00000204525/ENSG00000100285/ENSG00000136244/ENSG00000169429 DOID:525 central nervous system vasculitis 5/268 26/6421 0.00390070568894493 0.0234376520884613 ENSG00000090339/ENSG00000136244/ENSG00000157601/ENSG00000138378/ENSG00000150782 ICAM1/IL6/MX1/STAT4/IL18 3383/3569/4599/6775/3606 5 1 ENSG00000150782 4 ENSG00000090339/ENSG00000136244/ENSG00000157601/ENSG00000138378 DOID:4138 bile duct disease 8/268 62/6421 0.00395930171026798 0.0234376520884613 ENSG00000204525/ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000157601/ENSG00000197249/ENSG00000137462/ENSG00000241635 HLA-C/ICAM1/CCL5/IL6/MX1/SERPINA1/TLR2/UGT1A1 3107/3383/6352/3569/4599/5265/7097/54658 8 0 8 ENSG00000204525/ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000157601/ENSG00000197249/ENSG00000137462/ENSG00000241635 DOID:633 myositis 8/268 62/6421 0.00395930171026798 0.0234376520884613 ENSG00000115267/ENSG00000136244/ENSG00000169429/ENSG00000232810/ENSG00000164136/ENSG00000176697/ENSG00000146674/ENSG00000137462 IFIH1/IL6/CXCL8/TNF/IL15/BDNF/IGFBP3/TLR2 64135/3569/3576/7124/3600/627/3486/7097 8 2 ENSG00000176697/ENSG00000146674 6 ENSG00000115267/ENSG00000136244/ENSG00000169429/ENSG00000232810/ENSG00000164136/ENSG00000137462 DOID:5223 infertility 14/268 151/6421 0.00404442627583603 0.0237296869104362 ENSG00000139618/ENSG00000271503/ENSG00000136244/ENSG00000100918/ENSG00000006047/ENSG00000007038/ENSG00000006210/ENSG00000232810/ENSG00000164045/ENSG00000183770/ENSG00000176697/ENSG00000128342/ENSG00000005073/ENSG00000115232 BRCA2/CCL5/IL6/REC8/YBX2/PRSS21/CX3CL1/TNF/CDC25A/FOXL2/BDNF/LIF/HOXA11/ITGA4 675/6352/3569/9985/51087/10942/6376/7124/993/668/627/3976/3207/3676 14 2 ENSG00000183770/ENSG00000176697 12 ENSG00000139618/ENSG00000271503/ENSG00000136244/ENSG00000100918/ENSG00000006047/ENSG00000007038/ENSG00000006210/ENSG00000232810/ENSG00000164045/ENSG00000128342/ENSG00000005073/ENSG00000115232 DOID:50 thyroid gland disease 12/268 120/6421 0.00413183093171679 0.0240298588397213 ENSG00000234745/ENSG00000125347/ENSG00000204525/ENSG00000090339/ENSG00000115267/ENSG00000271503/ENSG00000136244/ENSG00000169248/ENSG00000169429/ENSG00000232810/ENSG00000146674/ENSG00000150782 HLA-B/IRF1/HLA-C/ICAM1/IFIH1/CCL5/IL6/CXCL11/CXCL8/TNF/IGFBP3/IL18 3106/3659/3107/3383/64135/6352/3569/6373/3576/7124/3486/3606 12 2 ENSG00000146674/ENSG00000150782 10 ENSG00000234745/ENSG00000125347/ENSG00000204525/ENSG00000090339/ENSG00000115267/ENSG00000271503/ENSG00000136244/ENSG00000169248/ENSG00000169429/ENSG00000232810 DOID:9741 biliary tract disease 8/268 63/6421 0.0043754721948733 0.0252255483930521 ENSG00000204525/ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000157601/ENSG00000197249/ENSG00000137462/ENSG00000241635 HLA-C/ICAM1/CCL5/IL6/MX1/SERPINA1/TLR2/UGT1A1 3107/3383/6352/3569/4599/5265/7097/54658 8 0 8 ENSG00000204525/ENSG00000090339/ENSG00000271503/ENSG00000136244/ENSG00000157601/ENSG00000197249/ENSG00000137462/ENSG00000241635 DOID:9352 type 2 diabetes mellitus 15/268 169/6421 0.00448663255379425 0.025564134892256 ENSG00000090339/ENSG00000115267/ENSG00000271503/ENSG00000170430/ENSG00000136244/ENSG00000168685/ENSG00000117594/ENSG00000169429/ENSG00000163661/ENSG00000164136/ENSG00000176697/ENSG00000146674/ENSG00000160255/ENSG00000150782/ENSG00000044574 ICAM1/IFIH1/CCL5/MGMT/IL6/IL7R/HSD11B1/CXCL8/PTX3/IL15/BDNF/IGFBP3/ITGB2/IL18/HSPA5 3383/64135/6352/4255/3569/3575/3290/3576/5806/3600/627/3486/3689/3606/3309 15 3 ENSG00000176697/ENSG00000146674/ENSG00000150782 12 ENSG00000090339/ENSG00000115267/ENSG00000271503/ENSG00000170430/ENSG00000136244/ENSG00000168685/ENSG00000117594/ENSG00000169429/ENSG00000163661/ENSG00000164136/ENSG00000160255/ENSG00000044574 DOID:3082 interstitial lung disease 13/268 137/6421 0.00453870877639762 0.025564134892256 ENSG00000115267/ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000184371/ENSG00000197249/ENSG00000232810/ENSG00000149968/ENSG00000176697/ENSG00000146674/ENSG00000145147/ENSG00000150782/ENSG00000100234 IFIH1/CCL5/IL6/CXCL8/CSF1/SERPINA1/TNF/MMP3/BDNF/IGFBP3/SLIT2/IL18/TIMP3 64135/6352/3569/3576/1435/5265/7124/4314/627/3486/9353/3606/7078 13 5 ENSG00000149968/ENSG00000176697/ENSG00000146674/ENSG00000150782/ENSG00000100234 8 ENSG00000115267/ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000184371/ENSG00000197249/ENSG00000232810/ENSG00000145147 DOID:12554 hemolytic-uremic syndrome 4/268 17/6421 0.00459128192144747 0.025564134892256 ENSG00000006210/ENSG00000000971/ENSG00000243649/ENSG00000164136 CX3CL1/CFH/CFB/IL15 6376/3075/629/3600 4 0 4 ENSG00000006210/ENSG00000000971/ENSG00000243649/ENSG00000164136 DOID:640 encephalomyelitis 4/268 17/6421 0.00459128192144747 0.025564134892256 ENSG00000125347/ENSG00000090339/ENSG00000232810/ENSG00000137462 IRF1/ICAM1/TNF/TLR2 3659/3383/7124/7097 4 0 4 ENSG00000125347/ENSG00000090339/ENSG00000232810/ENSG00000137462 DOID:349 systemic mastocytosis 5/268 27/6421 0.00462699274067981 0.025564134892256 ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000176697/ENSG00000101412 CCL5/IL6/CXCL8/BDNF/E2F1 6352/3569/3576/627/1869 5 1 ENSG00000176697 4 ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000101412 DOID:7166 thyroiditis 6/268 39/6421 0.00510803488594406 0.0279886539618257 ENSG00000234745/ENSG00000090339/ENSG00000115267/ENSG00000136244/ENSG00000169248/ENSG00000150782 HLA-B/ICAM1/IFIH1/IL6/CXCL11/IL18 3106/3383/64135/3569/6373/3606 6 1 ENSG00000150782 5 ENSG00000234745/ENSG00000090339/ENSG00000115267/ENSG00000136244/ENSG00000169248 DOID:4989 pancreatitis 9/268 79/6421 0.00534400096009641 0.0290415789880649 ENSG00000090339/ENSG00000136244/ENSG00000169429/ENSG00000006210/ENSG00000197249/ENSG00000232810/ENSG00000104267/ENSG00000137462/ENSG00000150782 ICAM1/IL6/CXCL8/CX3CL1/SERPINA1/TNF/CA2/TLR2/IL18 3383/3569/3576/6376/5265/7124/760/7097/3606 9 2 ENSG00000104267/ENSG00000150782 7 ENSG00000090339/ENSG00000136244/ENSG00000169429/ENSG00000006210/ENSG00000197249/ENSG00000232810/ENSG00000137462 DOID:28 endocrine system disease 22/268 294/6421 0.00539114502408351 0.0290595865932306 ENSG00000234745/ENSG00000125347/ENSG00000115415/ENSG00000204525/ENSG00000090339/ENSG00000115267/ENSG00000158050/ENSG00000271503/ENSG00000170430/ENSG00000136244/ENSG00000137752/ENSG00000169248/ENSG00000117594/ENSG00000169429/ENSG00000006210/ENSG00000197249/ENSG00000011201/ENSG00000232810/ENSG00000146674/ENSG00000104267/ENSG00000137462/ENSG00000150782 HLA-B/IRF1/STAT1/HLA-C/ICAM1/IFIH1/DUSP2/CCL5/MGMT/IL6/CASP1/CXCL11/HSD11B1/CXCL8/CX3CL1/SERPINA1/ANOS1/TNF/IGFBP3/CA2/TLR2/IL18 3106/3659/6772/3107/3383/64135/1844/6352/4255/3569/834/6373/3290/3576/6376/5265/3730/7124/3486/760/7097/3606 22 3 ENSG00000146674/ENSG00000104267/ENSG00000150782 19 ENSG00000234745/ENSG00000125347/ENSG00000115415/ENSG00000204525/ENSG00000090339/ENSG00000115267/ENSG00000158050/ENSG00000271503/ENSG00000170430/ENSG00000136244/ENSG00000137752/ENSG00000169248/ENSG00000117594/ENSG00000169429/ENSG00000006210/ENSG00000197249/ENSG00000011201/ENSG00000232810/ENSG00000137462 DOID:4251 conjunctival disease 5/268 28/6421 0.00544452126390836 0.0291106257900907 ENSG00000115415/ENSG00000090339/ENSG00000136244/ENSG00000120949/ENSG00000169429 STAT1/ICAM1/IL6/TNFRSF8/CXCL8 6772/3383/3569/943/3576 5 0 5 ENSG00000115415/ENSG00000090339/ENSG00000136244/ENSG00000120949/ENSG00000169429 DOID:1205 hypersensitivity reaction type I disease 10/268 94/6421 0.00555301610238577 0.0294531974070541 ENSG00000234745/ENSG00000204525/ENSG00000139618/ENSG00000055332/ENSG00000126561/ENSG00000120949/ENSG00000232810/ENSG00000206337/ENSG00000137462/ENSG00000150782 HLA-B/HLA-C/BRCA2/EIF2AK2/STAT5A/TNFRSF8/TNF/HCP5/TLR2/IL18 3106/3107/675/5610/6776/943/7124/10866/7097/3606 10 1 ENSG00000150782 9 ENSG00000234745/ENSG00000204525/ENSG00000139618/ENSG00000055332/ENSG00000126561/ENSG00000120949/ENSG00000232810/ENSG00000206337/ENSG00000137462 DOID:13378 Kawasaki disease 6/268 40/6421 0.0058040472563143 0.0305403438963205 ENSG00000234745/ENSG00000204525/ENSG00000232810/ENSG00000149968/ENSG00000099953/ENSG00000150782 HLA-B/HLA-C/TNF/MMP3/MMP11/IL18 3106/3107/7124/4314/4320/3606 6 2 ENSG00000149968/ENSG00000150782 4 ENSG00000234745/ENSG00000204525/ENSG00000232810/ENSG00000099953 DOID:6364 migraine 7/268 53/6421 0.00606716250058852 0.0316734546290566 ENSG00000090339/ENSG00000136244/ENSG00000232810/ENSG00000149968/ENSG00000111674/ENSG00000176697/ENSG00000160255 ICAM1/IL6/TNF/MMP3/ENO2/BDNF/ITGB2 3383/3569/7124/4314/2026/627/3689 7 2 ENSG00000149968/ENSG00000176697 5 ENSG00000090339/ENSG00000136244/ENSG00000232810/ENSG00000111674/ENSG00000160255 DOID:5082 liver cirrhosis 15/268 175/6421 0.00619335544329062 0.0320796457726694 ENSG00000185507/ENSG00000166710/ENSG00000090339/ENSG00000136244/ENSG00000168685/ENSG00000120949/ENSG00000169429/ENSG00000025708/ENSG00000197249/ENSG00000232810/ENSG00000149968/ENSG00000146674/ENSG00000188641/ENSG00000137462/ENSG00000150782 IRF7/B2M/ICAM1/IL6/IL7R/TNFRSF8/CXCL8/TYMP/SERPINA1/TNF/MMP3/IGFBP3/DPYD/TLR2/IL18 3665/567/3383/3569/3575/943/3576/1890/5265/7124/4314/3486/1806/7097/3606 15 3 ENSG00000149968/ENSG00000146674/ENSG00000150782 12 ENSG00000185507/ENSG00000166710/ENSG00000090339/ENSG00000136244/ENSG00000168685/ENSG00000120949/ENSG00000169429/ENSG00000025708/ENSG00000197249/ENSG00000232810/ENSG00000188641/ENSG00000137462 DOID:74 hematopoietic system disease 26/268 372/6421 0.00633572414195692 0.0324312421768847 ENSG00000234745/ENSG00000090339/ENSG00000139618/ENSG00000271503/ENSG00000136244/ENSG00000055332/ENSG00000023445/ENSG00000126561/ENSG00000120949/ENSG00000169429/ENSG00000006210/ENSG00000000971/ENSG00000232810/ENSG00000243649/ENSG00000164136/ENSG00000176697/ENSG00000146674/ENSG00000185339/ENSG00000160255/ENSG00000104267/ENSG00000137462/ENSG00000129757/ENSG00000101412/ENSG00000150782/ENSG00000241635/ENSG00000197299 HLA-B/ICAM1/BRCA2/CCL5/IL6/EIF2AK2/BIRC3/STAT5A/TNFRSF8/CXCL8/CX3CL1/CFH/TNF/CFB/IL15/BDNF/IGFBP3/TCN2/ITGB2/CA2/TLR2/CDKN1C/E2F1/IL18/UGT1A1/BLM 3106/3383/675/6352/3569/5610/330/6776/943/3576/6376/3075/7124/629/3600/627/3486/6948/3689/760/7097/1028/1869/3606/54658/641 26 4 ENSG00000176697/ENSG00000146674/ENSG00000104267/ENSG00000150782 22 ENSG00000234745/ENSG00000090339/ENSG00000139618/ENSG00000271503/ENSG00000136244/ENSG00000055332/ENSG00000023445/ENSG00000126561/ENSG00000120949/ENSG00000169429/ENSG00000006210/ENSG00000000971/ENSG00000232810/ENSG00000243649/ENSG00000164136/ENSG00000185339/ENSG00000160255/ENSG00000137462/ENSG00000129757/ENSG00000101412/ENSG00000241635/ENSG00000197299 DOID:811 lipodystrophy 5/268 29/6421 0.00635906709350681 0.0324312421768847 ENSG00000234745/ENSG00000136244/ENSG00000169429/ENSG00000232810/ENSG00000150782 HLA-B/IL6/CXCL8/TNF/IL18 3106/3569/3576/7124/3606 5 1 ENSG00000150782 4 ENSG00000234745/ENSG00000136244/ENSG00000169429/ENSG00000232810 DOID:11400 pyelonephritis 3/268 10/6421 0.0069352918875938 0.032691893218149 ENSG00000136244/ENSG00000120949/ENSG00000169429 IL6/TNFRSF8/CXCL8 3569/943/3576 3 0 3 ENSG00000136244/ENSG00000120949/ENSG00000169429 DOID:121 vaginal disease 3/268 10/6421 0.0069352918875938 0.032691893218149 ENSG00000136244/ENSG00000169429/ENSG00000137462 IL6/CXCL8/TLR2 3569/3576/7097 3 0 3 ENSG00000136244/ENSG00000169429/ENSG00000137462 DOID:12241 beta thalassemia 3/268 10/6421 0.0069352918875938 0.032691893218149 ENSG00000136244/ENSG00000169429/ENSG00000115232 IL6/CXCL8/ITGA4 3569/3576/3676 3 0 3 ENSG00000136244/ENSG00000169429/ENSG00000115232 DOID:1884 viral hepatitis 3/268 10/6421 0.0069352918875938 0.032691893218149 ENSG00000169429/ENSG00000115009/ENSG00000232810 CXCL8/CCL20/TNF 3576/6364/7124 3 0 3 ENSG00000169429/ENSG00000115009/ENSG00000232810 DOID:2170 vaginitis 3/268 10/6421 0.0069352918875938 0.032691893218149 ENSG00000136244/ENSG00000169429/ENSG00000137462 IL6/CXCL8/TLR2 3569/3576/7097 3 0 3 ENSG00000136244/ENSG00000169429/ENSG00000137462 DOID:2744 pyelitis 3/268 10/6421 0.0069352918875938 0.032691893218149 ENSG00000136244/ENSG00000120949/ENSG00000169429 IL6/TNFRSF8/CXCL8 3569/943/3576 3 0 3 ENSG00000136244/ENSG00000120949/ENSG00000169429 DOID:2945 severe acute respiratory syndrome 3/268 10/6421 0.0069352918875938 0.032691893218149 ENSG00000271503/ENSG00000136244/ENSG00000157601 CCL5/IL6/MX1 6352/3569/4599 3 0 3 ENSG00000271503/ENSG00000136244/ENSG00000157601 DOID:3086 gingival overgrowth 3/268 10/6421 0.0069352918875938 0.032691893218149 ENSG00000136244/ENSG00000164136/ENSG00000149968 IL6/IL15/MMP3 3569/3600/4314 3 1 ENSG00000149968 2 ENSG00000136244/ENSG00000164136 DOID:3385 bacterial vaginosis 3/268 10/6421 0.0069352918875938 0.032691893218149 ENSG00000136244/ENSG00000169429/ENSG00000137462 IL6/CXCL8/TLR2 3569/3576/7097 3 0 3 ENSG00000136244/ENSG00000169429/ENSG00000137462 DOID:13089 intracranial arterial disease 4/268 19/6421 0.00700188361535016 0.032691893218149 ENSG00000136244/ENSG00000232810/ENSG00000149968/ENSG00000100234 IL6/TNF/MMP3/TIMP3 3569/7124/4314/7078 4 2 ENSG00000149968/ENSG00000100234 2 ENSG00000136244/ENSG00000232810 DOID:3527 cerebral arterial disease 4/268 19/6421 0.00700188361535016 0.032691893218149 ENSG00000136244/ENSG00000232810/ENSG00000149968/ENSG00000100234 IL6/TNF/MMP3/TIMP3 3569/7124/4314/7078 4 2 ENSG00000149968/ENSG00000100234 2 ENSG00000136244/ENSG00000232810 DOID:9744 type 1 diabetes mellitus 4/268 19/6421 0.00700188361535016 0.032691893218149 ENSG00000136244/ENSG00000169429/ENSG00000232810/ENSG00000137462 IL6/CXCL8/TNF/TLR2 3569/3576/7124/7097 4 0 4 ENSG00000136244/ENSG00000169429/ENSG00000232810/ENSG00000137462 DOID:3083 chronic obstructive pulmonary disease 15/268 178/6421 0.00722453270088676 0.0334955607041113 ENSG00000115415/ENSG00000090339/ENSG00000271503/ENSG00000094804/ENSG00000136244/ENSG00000169248/ENSG00000169429/ENSG00000197249/ENSG00000232810/ENSG00000149968/ENSG00000160255/ENSG00000137462/ENSG00000150782/ENSG00000163131/ENSG00000069702 STAT1/ICAM1/CCL5/CDC6/IL6/CXCL11/CXCL8/SERPINA1/TNF/MMP3/ITGB2/TLR2/IL18/CTSS/TGFBR3 6772/3383/6352/990/3569/6373/3576/5265/7124/4314/3689/7097/3606/1520/7049 15 3 ENSG00000149968/ENSG00000150782/ENSG00000069702 12 ENSG00000115415/ENSG00000090339/ENSG00000271503/ENSG00000094804/ENSG00000136244/ENSG00000169248/ENSG00000169429/ENSG00000197249/ENSG00000232810/ENSG00000160255/ENSG00000137462/ENSG00000163131 DOID:3069 astrocytoma 10/268 98/6421 0.00743672865861878 0.0340314294399742 ENSG00000090339/ENSG00000170430/ENSG00000136244/ENSG00000160710/ENSG00000169429/ENSG00000253873/ENSG00000149968/ENSG00000141753/ENSG00000129757/ENSG00000258947 ICAM1/MGMT/IL6/ADAR/CXCL8/PCDHGA11/MMP3/IGFBP4/CDKN1C/TUBB3 3383/4255/3569/103/3576/56105/4314/3487/1028/10381 10 2 ENSG00000253873/ENSG00000149968 8 ENSG00000090339/ENSG00000170430/ENSG00000136244/ENSG00000160710/ENSG00000169429/ENSG00000141753/ENSG00000129757/ENSG00000258947 DOID:635 acquired immunodeficiency syndrome 7/268 55/6421 0.00744277114448907 0.0340314294399742 ENSG00000234745/ENSG00000204525/ENSG00000271503/ENSG00000179750/ENSG00000169248/ENSG00000150782/ENSG00000197299 HLA-B/HLA-C/CCL5/APOBEC3B/CXCL11/IL18/BLM 3106/3107/6352/9582/6373/3606/641 7 1 ENSG00000150782 6 ENSG00000234745/ENSG00000204525/ENSG00000271503/ENSG00000179750/ENSG00000169248/ENSG00000197299 DOID:11335 sarcoidosis 7/268 56/6421 0.00821123757508425 0.0370343572264004 ENSG00000234745/ENSG00000115415/ENSG00000136244/ENSG00000168685/ENSG00000232810/ENSG00000137462/ENSG00000150782 HLA-B/STAT1/IL6/IL7R/TNF/TLR2/IL18 3106/6772/3569/3575/7124/7097/3606 7 1 ENSG00000150782 6 ENSG00000234745/ENSG00000115415/ENSG00000136244/ENSG00000168685/ENSG00000232810/ENSG00000137462 DOID:76 stomach disease 7/268 56/6421 0.00821123757508425 0.0370343572264004 ENSG00000166710/ENSG00000170430/ENSG00000169429/ENSG00000115009/ENSG00000232810/ENSG00000240563/ENSG00000137462 B2M/MGMT/CXCL8/CCL20/TNF/L1TD1/TLR2 567/4255/3576/6364/7124/54596/7097 7 0 7 ENSG00000166710/ENSG00000170430/ENSG00000169429/ENSG00000115009/ENSG00000232810/ENSG00000240563/ENSG00000137462 DOID:11077 brucellosis 5/268 31/6421 0.00850170923197783 0.0378297531597403 ENSG00000136244/ENSG00000240065/ENSG00000204264/ENSG00000232810/ENSG00000137462 IL6/PSMB9/PSMB8/TNF/TLR2 3569/5698/5696/7124/7097 5 0 5 ENSG00000136244/ENSG00000240065/ENSG00000204264/ENSG00000232810/ENSG00000137462 DOID:350 mastocytosis 5/268 31/6421 0.00850170923197783 0.0378297531597403 ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000176697/ENSG00000101412 CCL5/IL6/CXCL8/BDNF/E2F1 6352/3569/3576/627/1869 5 1 ENSG00000176697 4 ENSG00000271503/ENSG00000136244/ENSG00000169429/ENSG00000101412 DOID:120 female reproductive organ cancer 27/268 402/6421 0.00912731751063886 0.0399978922330524 ENSG00000165949/ENSG00000188313/ENSG00000079385/ENSG00000139618/ENSG00000170430/ENSG00000136244/ENSG00000137752/ENSG00000185885/ENSG00000163739/ENSG00000066923/ENSG00000133321/ENSG00000076706/ENSG00000169429/ENSG00000181885/ENSG00000038427/ENSG00000025708/ENSG00000232810/ENSG00000164136/ENSG00000149968/ENSG00000176697/ENSG00000146674/ENSG00000128342/ENSG00000188641/ENSG00000206073/ENSG00000135480/ENSG00000150782/ENSG00000100234 IFI27/PLSCR1/CEACAM1/BRCA2/MGMT/IL6/CASP1/IFITM1/CXCL1/STAG3/RARRES3/MCAM/CXCL8/CLDN7/VCAN/TYMP/TNF/IL15/MMP3/BDNF/IGFBP3/LIF/DPYD/SERPINB4/KRT7/IL18/TIMP3 3429/5359/634/675/4255/3569/834/8519/2919/10734/5920/4162/3576/1366/1462/1890/7124/3600/4314/627/3486/3976/1806/6318/3855/3606/7078 27 6 ENSG00000038427/ENSG00000149968/ENSG00000176697/ENSG00000146674/ENSG00000150782/ENSG00000100234 21 ENSG00000165949/ENSG00000188313/ENSG00000079385/ENSG00000139618/ENSG00000170430/ENSG00000136244/ENSG00000137752/ENSG00000185885/ENSG00000163739/ENSG00000066923/ENSG00000133321/ENSG00000076706/ENSG00000169429/ENSG00000181885/ENSG00000025708/ENSG00000232810/ENSG00000164136/ENSG00000128342/ENSG00000188641/ENSG00000206073/ENSG00000135480 DOID:2055 post-traumatic stress disorder 3/268 11/6421 0.00924496800471408 0.0399978922330524 ENSG00000136244/ENSG00000169429/ENSG00000176697 IL6/CXCL8/BDNF 3569/3576/627 3 1 ENSG00000176697 2 ENSG00000136244/ENSG00000169429 DOID:2957 pulmonary tuberculosis 3/268 11/6421 0.00924496800471408 0.0399978922330524 ENSG00000271503/ENSG00000163661/ENSG00000150782 CCL5/PTX3/IL18 6352/5806/3606 3 1 ENSG00000150782 2 ENSG00000271503/ENSG00000163661 DOID:1602 lymphadenitis 6/268 44/6421 0.00929061146891414 0.0399978922330524 ENSG00000234745/ENSG00000204525/ENSG00000232810/ENSG00000149968/ENSG00000099953/ENSG00000150782 HLA-B/HLA-C/TNF/MMP3/MMP11/IL18 3106/3107/7124/4314/4320/3606 6 2 ENSG00000149968/ENSG00000150782 4 ENSG00000234745/ENSG00000204525/ENSG00000232810/ENSG00000099953 DOID:9942 lymph node disease 6/268 44/6421 0.00929061146891414 0.0399978922330524 ENSG00000234745/ENSG00000204525/ENSG00000232810/ENSG00000149968/ENSG00000099953/ENSG00000150782 HLA-B/HLA-C/TNF/MMP3/MMP11/IL18 3106/3107/7124/4314/4320/3606 6 2 ENSG00000149968/ENSG00000150782 4 ENSG00000234745/ENSG00000204525/ENSG00000232810/ENSG00000099953 DOID:12603 acute leukemia 9/268 87/6421 0.00997894986549221 0.0426841532956215 ENSG00000139618/ENSG00000170430/ENSG00000136244/ENSG00000055332/ENSG00000120949/ENSG00000169429/ENSG00000198286/ENSG00000101115/ENSG00000169403 BRCA2/MGMT/IL6/EIF2AK2/TNFRSF8/CXCL8/CARD11/SALL4/PTAFR 675/4255/3569/5610/943/3576/84433/57167/5724 9 1 ENSG00000198286 8 ENSG00000139618/ENSG00000170430/ENSG00000136244/ENSG00000055332/ENSG00000120949/ENSG00000169429/ENSG00000101115/ENSG00000169403 DOID:13129 severe pre-eclampsia 4/268 21/6421 0.0101263992544131 0.0430371968312556 ENSG00000136244/ENSG00000169429/ENSG00000000971/ENSG00000129757 IL6/CXCL8/CFH/CDKN1C 3569/3576/3075/1028 4 0 4 ENSG00000136244/ENSG00000169429/ENSG00000000971/ENSG00000129757 DOID:1040 chronic lymphocytic leukemia 14/268 168/6421 0.0102244920918765 0.0431773137383066 ENSG00000115415/ENSG00000166710/ENSG00000162892/ENSG00000136244/ENSG00000055332/ENSG00000023445/ENSG00000141682/ENSG00000132530/ENSG00000169429/ENSG00000197646/ENSG00000232810/ENSG00000102962/ENSG00000099250/ENSG00000115232 STAT1/B2M/IL24/IL6/EIF2AK2/BIRC3/PMAIP1/XAF1/CXCL8/PDCD1LG2/TNF/CCL22/NRP1/ITGA4 6772/567/11009/3569/5610/330/5366/54739/3576/80380/7124/6367/8829/3676 14 0 14 ENSG00000115415/ENSG00000166710/ENSG00000162892/ENSG00000136244/ENSG00000055332/ENSG00000023445/ENSG00000141682/ENSG00000132530/ENSG00000169429/ENSG00000197646/ENSG00000232810/ENSG00000102962/ENSG00000099250/ENSG00000115232 DOID:10608 celiac disease 7/268 59/6421 0.0108675513192553 0.0456024463586473 ENSG00000125347/ENSG00000115415/ENSG00000090339/ENSG00000136244/ENSG00000169429/ENSG00000232810/ENSG00000164136 IRF1/STAT1/ICAM1/IL6/CXCL8/TNF/IL15 3659/6772/3383/3569/3576/7124/3600 7 0 7 ENSG00000125347/ENSG00000115415/ENSG00000090339/ENSG00000136244/ENSG00000169429/ENSG00000232810/ENSG00000164136 DOID:26 pancreas disease 11/268 120/6421 0.0112124457672772 0.0467537832937407 ENSG00000115415/ENSG00000090339/ENSG00000136244/ENSG00000137752/ENSG00000169429/ENSG00000006210/ENSG00000197249/ENSG00000232810/ENSG00000104267/ENSG00000137462/ENSG00000150782 STAT1/ICAM1/IL6/CASP1/CXCL8/CX3CL1/SERPINA1/TNF/CA2/TLR2/IL18 6772/3383/3569/834/3576/6376/5265/7124/760/7097/3606 11 2 ENSG00000104267/ENSG00000150782 9 ENSG00000115415/ENSG00000090339/ENSG00000136244/ENSG00000137752/ENSG00000169429/ENSG00000006210/ENSG00000197249/ENSG00000232810/ENSG00000137462 DOID:2916 hypersensitivity reaction type IV disease 7/268 60/6421 0.0118777233764478 0.0486113250492562 ENSG00000234745/ENSG00000115415/ENSG00000136244/ENSG00000168685/ENSG00000232810/ENSG00000137462/ENSG00000150782 HLA-B/STAT1/IL6/IL7R/TNF/TLR2/IL18 3106/6772/3569/3575/7124/7097/3606 7 1 ENSG00000150782 6 ENSG00000234745/ENSG00000115415/ENSG00000136244/ENSG00000168685/ENSG00000232810/ENSG00000137462 DOID:10140 dry eye syndrome 3/268 12/6421 0.0119512005777206 0.0486113250492562 ENSG00000136244/ENSG00000160710/ENSG00000055332 IL6/ADAR/EIF2AK2 3569/103/5610 3 0 3 ENSG00000136244/ENSG00000160710/ENSG00000055332 DOID:11465 autonomic nervous system disease 3/268 12/6421 0.0119512005777206 0.0486113250492562 ENSG00000234745/ENSG00000136244/ENSG00000232810 HLA-B/IL6/TNF 3106/3569/7124 3 0 3 ENSG00000234745/ENSG00000136244/ENSG00000232810 DOID:1400 lacrimal apparatus disease 3/268 12/6421 0.0119512005777206 0.0486113250492562 ENSG00000136244/ENSG00000160710/ENSG00000055332 IL6/ADAR/EIF2AK2 3569/103/5610 3 0 3 ENSG00000136244/ENSG00000160710/ENSG00000055332