DOID Description GeneRatio BgRatio pvalue padj geneID geneName EntrezID Count Up Up_Gene_names Down Down_Gene_names DOID:0050161 lower respiratory tract disease 50/433 390/6411 5.63764655222765e-06 0.0015704456947104 ENSG00000165949/ENSG00000103811/ENSG00000106366/ENSG00000115415/ENSG00000149948/ENSG00000122691/ENSG00000197249/ENSG00000157873/ENSG00000146674/ENSG00000178573/ENSG00000124731/ENSG00000163661/ENSG00000181104/ENSG00000006210/ENSG00000130702/ENSG00000145147/ENSG00000166949/ENSG00000100985/ENSG00000156804/ENSG00000011422/ENSG00000118194/ENSG00000184371/ENSG00000100234/ENSG00000140279/ENSG00000023909/ENSG00000116701/ENSG00000169896/ENSG00000115602/ENSG00000169252/ENSG00000065361/ENSG00000104368/ENSG00000057149/ENSG00000069702/ENSG00000196611/ENSG00000138696/ENSG00000166828/ENSG00000189143/ENSG00000115008/ENSG00000104371/ENSG00000117525/ENSG00000136244/ENSG00000119630/ENSG00000105974/ENSG00000239732/ENSG00000197405/ENSG00000148926/ENSG00000164683/ENSG00000115604/ENSG00000169194/ENSG00000140465 IFI27/CTSH/SERPINE1/STAT1/HMGA2/TWIST1/SERPINA1/TNFRSF14/IGFBP3/MAF/TREM1/PTX3/F2R/CX3CL1/LAMA5/SLIT2/SMAD3/MMP9/FBXO32/PLAUR/TNNT2/CSF1/TIMP3/DUOX2/GCLM/NCF2/ITGAM/IL1RL1/ADRB2/ERBB3/PLAT/SERPINB3/TGFBR3/MMP1/BMPR1B/SCNN1G/CLDN4/IL1A/DKK4/F3/IL6/PGF/CAV1/TLR9/C5AR1/ADM/HEY1/IL18R1/IL13/CYP1A1 3429/1512/5054/6772/8091/7291/5265/8764/3486/4094/54210/5806/2149/6376/3911/9353/4088/4318/114907/5329/7139/1435/7078/50506/2730/4688/3684/9173/154/2065/5327/6317/7049/4312/658/6340/1364/3552/27121/2152/3569/5228/857/54106/728/133/23462/8809/3596/1543 50 21 ENSG00000103811/ENSG00000146674/ENSG00000181104/ENSG00000130702/ENSG00000145147/ENSG00000166949/ENSG00000156804/ENSG00000118194/ENSG00000100234/ENSG00000140279/ENSG00000116701/ENSG00000169252/ENSG00000065361/ENSG00000057149/ENSG00000069702/ENSG00000189143/ENSG00000117525/ENSG00000105974/ENSG00000239732/ENSG00000148926/ENSG00000140465 29 ENSG00000165949/ENSG00000106366/ENSG00000115415/ENSG00000149948/ENSG00000122691/ENSG00000197249/ENSG00000157873/ENSG00000178573/ENSG00000124731/ENSG00000163661/ENSG00000006210/ENSG00000100985/ENSG00000011422/ENSG00000184371/ENSG00000023909/ENSG00000169896/ENSG00000115602/ENSG00000104368/ENSG00000196611/ENSG00000138696/ENSG00000166828/ENSG00000115008/ENSG00000104371/ENSG00000136244/ENSG00000119630/ENSG00000197405/ENSG00000164683/ENSG00000115604/ENSG00000169194 DOID:1579 respiratory system disease 54/433 434/6411 5.73469049472394e-06 0.0015704456947104 ENSG00000165949/ENSG00000103811/ENSG00000234745/ENSG00000106366/ENSG00000137033/ENSG00000115415/ENSG00000149948/ENSG00000122691/ENSG00000146648/ENSG00000197249/ENSG00000157873/ENSG00000146674/ENSG00000178573/ENSG00000124731/ENSG00000163661/ENSG00000181104/ENSG00000006210/ENSG00000130702/ENSG00000145147/ENSG00000166949/ENSG00000100985/ENSG00000156804/ENSG00000185436/ENSG00000011422/ENSG00000118194/ENSG00000184371/ENSG00000100234/ENSG00000140279/ENSG00000023909/ENSG00000116701/ENSG00000169896/ENSG00000115602/ENSG00000169252/ENSG00000065361/ENSG00000104368/ENSG00000057149/ENSG00000069702/ENSG00000196611/ENSG00000138696/ENSG00000166828/ENSG00000189143/ENSG00000115008/ENSG00000104371/ENSG00000117525/ENSG00000136244/ENSG00000119630/ENSG00000105974/ENSG00000239732/ENSG00000197405/ENSG00000148926/ENSG00000164683/ENSG00000115604/ENSG00000169194/ENSG00000140465 IFI27/CTSH/HLA-B/SERPINE1/IL33/STAT1/HMGA2/TWIST1/EGFR/SERPINA1/TNFRSF14/IGFBP3/MAF/TREM1/PTX3/F2R/CX3CL1/LAMA5/SLIT2/SMAD3/MMP9/FBXO32/IFNLR1/PLAUR/TNNT2/CSF1/TIMP3/DUOX2/GCLM/NCF2/ITGAM/IL1RL1/ADRB2/ERBB3/PLAT/SERPINB3/TGFBR3/MMP1/BMPR1B/SCNN1G/CLDN4/IL1A/DKK4/F3/IL6/PGF/CAV1/TLR9/C5AR1/ADM/HEY1/IL18R1/IL13/CYP1A1 3429/1512/3106/5054/90865/6772/8091/7291/1956/5265/8764/3486/4094/54210/5806/2149/6376/3911/9353/4088/4318/114907/163702/5329/7139/1435/7078/50506/2730/4688/3684/9173/154/2065/5327/6317/7049/4312/658/6340/1364/3552/27121/2152/3569/5228/857/54106/728/133/23462/8809/3596/1543 54 23 ENSG00000103811/ENSG00000146648/ENSG00000146674/ENSG00000181104/ENSG00000130702/ENSG00000145147/ENSG00000166949/ENSG00000156804/ENSG00000185436/ENSG00000118194/ENSG00000100234/ENSG00000140279/ENSG00000116701/ENSG00000169252/ENSG00000065361/ENSG00000057149/ENSG00000069702/ENSG00000189143/ENSG00000117525/ENSG00000105974/ENSG00000239732/ENSG00000148926/ENSG00000140465 31 ENSG00000165949/ENSG00000234745/ENSG00000106366/ENSG00000137033/ENSG00000115415/ENSG00000149948/ENSG00000122691/ENSG00000197249/ENSG00000157873/ENSG00000178573/ENSG00000124731/ENSG00000163661/ENSG00000006210/ENSG00000100985/ENSG00000011422/ENSG00000184371/ENSG00000023909/ENSG00000169896/ENSG00000115602/ENSG00000104368/ENSG00000196611/ENSG00000138696/ENSG00000166828/ENSG00000115008/ENSG00000104371/ENSG00000136244/ENSG00000119630/ENSG00000197405/ENSG00000164683/ENSG00000115604/ENSG00000169194 DOID:850 lung disease 49/433 382/6411 6.94847072052938e-06 0.0015704456947104 ENSG00000165949/ENSG00000103811/ENSG00000106366/ENSG00000115415/ENSG00000149948/ENSG00000122691/ENSG00000197249/ENSG00000157873/ENSG00000146674/ENSG00000178573/ENSG00000124731/ENSG00000163661/ENSG00000181104/ENSG00000006210/ENSG00000130702/ENSG00000145147/ENSG00000166949/ENSG00000100985/ENSG00000156804/ENSG00000011422/ENSG00000118194/ENSG00000184371/ENSG00000100234/ENSG00000140279/ENSG00000023909/ENSG00000116701/ENSG00000169896/ENSG00000115602/ENSG00000169252/ENSG00000065361/ENSG00000104368/ENSG00000057149/ENSG00000069702/ENSG00000196611/ENSG00000138696/ENSG00000189143/ENSG00000115008/ENSG00000104371/ENSG00000117525/ENSG00000136244/ENSG00000119630/ENSG00000105974/ENSG00000239732/ENSG00000197405/ENSG00000148926/ENSG00000164683/ENSG00000115604/ENSG00000169194/ENSG00000140465 IFI27/CTSH/SERPINE1/STAT1/HMGA2/TWIST1/SERPINA1/TNFRSF14/IGFBP3/MAF/TREM1/PTX3/F2R/CX3CL1/LAMA5/SLIT2/SMAD3/MMP9/FBXO32/PLAUR/TNNT2/CSF1/TIMP3/DUOX2/GCLM/NCF2/ITGAM/IL1RL1/ADRB2/ERBB3/PLAT/SERPINB3/TGFBR3/MMP1/BMPR1B/CLDN4/IL1A/DKK4/F3/IL6/PGF/CAV1/TLR9/C5AR1/ADM/HEY1/IL18R1/IL13/CYP1A1 3429/1512/5054/6772/8091/7291/5265/8764/3486/4094/54210/5806/2149/6376/3911/9353/4088/4318/114907/5329/7139/1435/7078/50506/2730/4688/3684/9173/154/2065/5327/6317/7049/4312/658/1364/3552/27121/2152/3569/5228/857/54106/728/133/23462/8809/3596/1543 49 21 ENSG00000103811/ENSG00000146674/ENSG00000181104/ENSG00000130702/ENSG00000145147/ENSG00000166949/ENSG00000156804/ENSG00000118194/ENSG00000100234/ENSG00000140279/ENSG00000116701/ENSG00000169252/ENSG00000065361/ENSG00000057149/ENSG00000069702/ENSG00000189143/ENSG00000117525/ENSG00000105974/ENSG00000239732/ENSG00000148926/ENSG00000140465 28 ENSG00000165949/ENSG00000106366/ENSG00000115415/ENSG00000149948/ENSG00000122691/ENSG00000197249/ENSG00000157873/ENSG00000178573/ENSG00000124731/ENSG00000163661/ENSG00000006210/ENSG00000100985/ENSG00000011422/ENSG00000184371/ENSG00000023909/ENSG00000169896/ENSG00000115602/ENSG00000104368/ENSG00000196611/ENSG00000138696/ENSG00000115008/ENSG00000104371/ENSG00000136244/ENSG00000119630/ENSG00000197405/ENSG00000164683/ENSG00000115604/ENSG00000169194 DOID:37 skin disease 38/433 269/6411 8.79801509641683e-06 0.0015704456947104 ENSG00000234745/ENSG00000112964/ENSG00000049130/ENSG00000167768/ENSG00000146648/ENSG00000128342/ENSG00000072274/ENSG00000157873/ENSG00000146674/ENSG00000181104/ENSG00000206337/ENSG00000006210/ENSG00000149131/ENSG00000130702/ENSG00000166949/ENSG00000100985/ENSG00000133710/ENSG00000124762/ENSG00000011422/ENSG00000134760/ENSG00000115602/ENSG00000169252/ENSG00000073111/ENSG00000011201/ENSG00000169035/ENSG00000163207/ENSG00000196611/ENSG00000115008/ENSG00000117525/ENSG00000136244/ENSG00000132965/ENSG00000119630/ENSG00000105974/ENSG00000096696/ENSG00000064300/ENSG00000169194/ENSG00000162924/ENSG00000140465 HLA-B/GHR/KITLG/KRT1/EGFR/LIF/TFRC/TNFRSF14/IGFBP3/F2R/HCP5/CX3CL1/SERPING1/LAMA5/SMAD3/MMP9/SPINK5/CDKN1A/PLAUR/DSG1/IL1RL1/ADRB2/MCM2/ANOS1/KLK7/IVL/MMP1/IL1A/F3/IL6/ALOX5AP/PGF/CAV1/DSP/NGFR/IL13/REL/CYP1A1 3106/2690/4254/3848/1956/3976/7037/8764/3486/2149/10866/6376/710/3911/4088/4318/11005/1026/5329/1828/9173/154/4171/3730/5650/3713/4312/3552/2152/3569/241/5228/857/1832/4804/3596/5966/1543 38 18 ENSG00000167768/ENSG00000146648/ENSG00000072274/ENSG00000146674/ENSG00000181104/ENSG00000130702/ENSG00000166949/ENSG00000133710/ENSG00000134760/ENSG00000169252/ENSG00000073111/ENSG00000169035/ENSG00000163207/ENSG00000117525/ENSG00000105974/ENSG00000096696/ENSG00000162924/ENSG00000140465 20 ENSG00000234745/ENSG00000112964/ENSG00000049130/ENSG00000128342/ENSG00000157873/ENSG00000206337/ENSG00000006210/ENSG00000149131/ENSG00000100985/ENSG00000124762/ENSG00000011422/ENSG00000115602/ENSG00000011201/ENSG00000196611/ENSG00000115008/ENSG00000136244/ENSG00000132965/ENSG00000119630/ENSG00000064300/ENSG00000169194 DOID:16 integumentary system disease 41/433 306/6411 1.44080376633562e-05 0.00205746777832726 ENSG00000234745/ENSG00000112964/ENSG00000168453/ENSG00000049130/ENSG00000167768/ENSG00000146648/ENSG00000128342/ENSG00000072274/ENSG00000157873/ENSG00000146674/ENSG00000181104/ENSG00000206337/ENSG00000006210/ENSG00000149131/ENSG00000130702/ENSG00000166949/ENSG00000100985/ENSG00000133710/ENSG00000124762/ENSG00000011422/ENSG00000134760/ENSG00000136695/ENSG00000115602/ENSG00000169252/ENSG00000073111/ENSG00000011201/ENSG00000169035/ENSG00000134762/ENSG00000163207/ENSG00000196611/ENSG00000115008/ENSG00000117525/ENSG00000136244/ENSG00000132965/ENSG00000119630/ENSG00000105974/ENSG00000096696/ENSG00000064300/ENSG00000169194/ENSG00000162924/ENSG00000140465 HLA-B/GHR/HR/KITLG/KRT1/EGFR/LIF/TFRC/TNFRSF14/IGFBP3/F2R/HCP5/CX3CL1/SERPING1/LAMA5/SMAD3/MMP9/SPINK5/CDKN1A/PLAUR/DSG1/IL36RN/IL1RL1/ADRB2/MCM2/ANOS1/KLK7/DSC3/IVL/MMP1/IL1A/F3/IL6/ALOX5AP/PGF/CAV1/DSP/NGFR/IL13/REL/CYP1A1 3106/2690/55806/4254/3848/1956/3976/7037/8764/3486/2149/10866/6376/710/3911/4088/4318/11005/1026/5329/1828/26525/9173/154/4171/3730/5650/1825/3713/4312/3552/2152/3569/241/5228/857/1832/4804/3596/5966/1543 41 21 ENSG00000168453/ENSG00000167768/ENSG00000146648/ENSG00000072274/ENSG00000146674/ENSG00000181104/ENSG00000130702/ENSG00000166949/ENSG00000133710/ENSG00000134760/ENSG00000136695/ENSG00000169252/ENSG00000073111/ENSG00000169035/ENSG00000134762/ENSG00000163207/ENSG00000117525/ENSG00000105974/ENSG00000096696/ENSG00000162924/ENSG00000140465 20 ENSG00000234745/ENSG00000112964/ENSG00000049130/ENSG00000128342/ENSG00000157873/ENSG00000206337/ENSG00000006210/ENSG00000149131/ENSG00000100985/ENSG00000124762/ENSG00000011422/ENSG00000115602/ENSG00000011201/ENSG00000196611/ENSG00000115008/ENSG00000136244/ENSG00000132965/ENSG00000119630/ENSG00000064300/ENSG00000169194 DOID:3770 pulmonary fibrosis 19/433 101/6411 3.58533649685885e-05 0.00426655043126203 ENSG00000122691/ENSG00000146674/ENSG00000124731/ENSG00000181104/ENSG00000145147/ENSG00000100985/ENSG00000184371/ENSG00000100234/ENSG00000116701/ENSG00000065361/ENSG00000057149/ENSG00000196611/ENSG00000115008/ENSG00000104371/ENSG00000136244/ENSG00000105974/ENSG00000239732/ENSG00000164683/ENSG00000169194 TWIST1/IGFBP3/TREM1/F2R/SLIT2/MMP9/CSF1/TIMP3/NCF2/ERBB3/SERPINB3/MMP1/IL1A/DKK4/IL6/CAV1/TLR9/HEY1/IL13 7291/3486/54210/2149/9353/4318/1435/7078/4688/2065/6317/4312/3552/27121/3569/857/54106/23462/3596 19 9 ENSG00000146674/ENSG00000181104/ENSG00000145147/ENSG00000100234/ENSG00000116701/ENSG00000065361/ENSG00000057149/ENSG00000105974/ENSG00000239732 10 ENSG00000122691/ENSG00000124731/ENSG00000100985/ENSG00000184371/ENSG00000196611/ENSG00000115008/ENSG00000104371/ENSG00000136244/ENSG00000164683/ENSG00000169194 DOID:10124 corneal disease 12/433 48/6411 5.76617531186292e-05 0.00588149881810018 ENSG00000142227/ENSG00000092969/ENSG00000144810/ENSG00000100985/ENSG00000124762/ENSG00000011422/ENSG00000184292/ENSG00000067082/ENSG00000117525/ENSG00000119699/ENSG00000239732/ENSG00000140465 EMP3/TGFB2/COL8A1/MMP9/CDKN1A/PLAUR/TACSTD2/KLF6/F3/TGFB3/TLR9/CYP1A1 2014/7042/1295/4318/1026/5329/4070/1316/2152/7043/54106/1543 12 7 ENSG00000092969/ENSG00000184292/ENSG00000067082/ENSG00000117525/ENSG00000119699/ENSG00000239732/ENSG00000140465 5 ENSG00000142227/ENSG00000144810/ENSG00000100985/ENSG00000124762/ENSG00000011422 DOID:9588 encephalitis 11/433 44/6411 0.000117412376641269 0.0104790546152332 ENSG00000134321/ENSG00000187608/ENSG00000115415/ENSG00000111335/ENSG00000163661/ENSG00000006210/ENSG00000174469/ENSG00000186868/ENSG00000189058/ENSG00000136244/ENSG00000111331 RSAD2/ISG15/STAT1/OAS2/PTX3/CX3CL1/CNTNAP2/MAPT/APOD/IL6/OAS3 91543/9636/6772/4939/5806/6376/26047/4137/347/3569/4940 11 1 ENSG00000186868 10 ENSG00000134321/ENSG00000187608/ENSG00000115415/ENSG00000111335/ENSG00000163661/ENSG00000006210/ENSG00000174469/ENSG00000189058/ENSG00000136244/ENSG00000111331 DOID:0060072 benign neoplasm 52/433 469/6411 0.000199287383714289 0.015314107029729 ENSG00000154646/ENSG00000170430/ENSG00000106366/ENSG00000077942/ENSG00000112964/ENSG00000049130/ENSG00000106484/ENSG00000135679/ENSG00000163739/ENSG00000149948/ENSG00000122691/ENSG00000146648/ENSG00000183734/ENSG00000143878/ENSG00000128342/ENSG00000117594/ENSG00000196730/ENSG00000168477/ENSG00000075213/ENSG00000146674/ENSG00000087494/ENSG00000099250/ENSG00000100097/ENSG00000136205/ENSG00000123342/ENSG00000079385/ENSG00000120738/ENSG00000166949/ENSG00000020922/ENSG00000100985/ENSG00000187244/ENSG00000124762/ENSG00000011422/ENSG00000170776/ENSG00000166670/ENSG00000073111/ENSG00000104368/ENSG00000140937/ENSG00000196611/ENSG00000197956/ENSG00000163347/ENSG00000173267/ENSG00000165887/ENSG00000136244/ENSG00000211445/ENSG00000105974/ENSG00000119699/ENSG00000064300/ENSG00000069482/ENSG00000148926/ENSG00000163083/ENSG00000140465 TMPRSS15/MGMT/SERPINE1/FBLN1/GHR/KITLG/MEST/MDM2/CXCL1/HMGA2/TWIST1/EGFR/ASCL2/RHOB/LIF/HSD11B1/DAPK1/TNXB/SEMA3A/IGFBP3/PTHLH/NRP1/LGALS1/TNS3/MMP19/CEACAM1/EGR1/SMAD3/MRE11/MMP9/BCAM/CDKN1A/PLAUR/AKAP13/MMP10/MCM2/PLAT/CDH11/MMP1/S100A6/CLDN1/SNCG/ANKRD2/IL6/GPX3/CAV1/TGFB3/NGFR/GAL/ADM/INHBB/CYP1A1 5651/4255/5054/2192/2690/4254/4232/4193/2919/8091/7291/1956/430/388/3976/3290/1612/7148/10371/3486/5744/8829/3956/64759/4327/634/1958/4088/4361/4318/4059/1026/5329/11214/4319/4171/5327/1009/4312/6277/9076/6623/26287/3569/2878/857/7043/4804/51083/133/3625/1543 52 22 ENSG00000154646/ENSG00000077942/ENSG00000106484/ENSG00000146648/ENSG00000183734/ENSG00000168477/ENSG00000146674/ENSG00000136205/ENSG00000120738/ENSG00000166949/ENSG00000020922/ENSG00000187244/ENSG00000170776/ENSG00000073111/ENSG00000163347/ENSG00000173267/ENSG00000165887/ENSG00000211445/ENSG00000105974/ENSG00000119699/ENSG00000148926/ENSG00000140465 30 ENSG00000170430/ENSG00000106366/ENSG00000112964/ENSG00000049130/ENSG00000135679/ENSG00000163739/ENSG00000149948/ENSG00000122691/ENSG00000143878/ENSG00000128342/ENSG00000117594/ENSG00000196730/ENSG00000075213/ENSG00000087494/ENSG00000099250/ENSG00000100097/ENSG00000123342/ENSG00000079385/ENSG00000100985/ENSG00000124762/ENSG00000011422/ENSG00000166670/ENSG00000104368/ENSG00000140937/ENSG00000196611/ENSG00000197956/ENSG00000136244/ENSG00000064300/ENSG00000069482/ENSG00000163083 DOID:2600 laryngeal carcinoma 8/433 26/6411 0.000214483291732899 0.015314107029729 ENSG00000178934/ENSG00000100097/ENSG00000100985/ENSG00000124762/ENSG00000196611/ENSG00000136244/ENSG00000105974/ENSG00000169194 LGALS7B/LGALS1/MMP9/CDKN1A/MMP1/IL6/CAV1/IL13 653499/3956/4318/1026/4312/3569/857/3596 8 1 ENSG00000105974 7 ENSG00000178934/ENSG00000100097/ENSG00000100985/ENSG00000124762/ENSG00000196611/ENSG00000136244/ENSG00000169194 DOID:0060085 organ system benign neoplasm 29/433 217/6411 0.000280021038324663 0.0181759110330736 ENSG00000170430/ENSG00000106366/ENSG00000077942/ENSG00000112964/ENSG00000049130/ENSG00000135679/ENSG00000163739/ENSG00000149948/ENSG00000146648/ENSG00000183734/ENSG00000143878/ENSG00000128342/ENSG00000168477/ENSG00000075213/ENSG00000146674/ENSG00000123342/ENSG00000120738/ENSG00000100985/ENSG00000187244/ENSG00000124762/ENSG00000166670/ENSG00000073111/ENSG00000104368/ENSG00000197956/ENSG00000165887/ENSG00000136244/ENSG00000105974/ENSG00000119699/ENSG00000064300 MGMT/SERPINE1/FBLN1/GHR/KITLG/MDM2/CXCL1/HMGA2/EGFR/ASCL2/RHOB/LIF/TNXB/SEMA3A/IGFBP3/MMP19/EGR1/MMP9/BCAM/CDKN1A/MMP10/MCM2/PLAT/S100A6/ANKRD2/IL6/CAV1/TGFB3/NGFR 4255/5054/2192/2690/4254/4193/2919/8091/1956/430/388/3976/7148/10371/3486/4327/1958/4318/4059/1026/4319/4171/5327/6277/26287/3569/857/7043/4804 29 11 ENSG00000077942/ENSG00000146648/ENSG00000183734/ENSG00000168477/ENSG00000146674/ENSG00000120738/ENSG00000187244/ENSG00000073111/ENSG00000165887/ENSG00000105974/ENSG00000119699 18 ENSG00000170430/ENSG00000106366/ENSG00000112964/ENSG00000049130/ENSG00000135679/ENSG00000163739/ENSG00000149948/ENSG00000143878/ENSG00000128342/ENSG00000075213/ENSG00000123342/ENSG00000100985/ENSG00000124762/ENSG00000166670/ENSG00000104368/ENSG00000197956/ENSG00000136244/ENSG00000064300 DOID:5100 middle ear disease 7/433 21/6411 0.000309206374896629 0.0183977793063494 ENSG00000106366/ENSG00000146648/ENSG00000100985/ENSG00000124762/ENSG00000113916/ENSG00000136244/ENSG00000119630 SERPINE1/EGFR/MMP9/CDKN1A/BCL6/IL6/PGF 5054/1956/4318/1026/604/3569/5228 7 2 ENSG00000146648/ENSG00000113916 5 ENSG00000106366/ENSG00000100985/ENSG00000124762/ENSG00000136244/ENSG00000119630 DOID:2320 obstructive lung disease 30/433 236/6411 0.000526968288279605 0.0289074457879859 ENSG00000106366/ENSG00000115415/ENSG00000197249/ENSG00000157873/ENSG00000178573/ENSG00000124731/ENSG00000006210/ENSG00000130702/ENSG00000166949/ENSG00000100985/ENSG00000156804/ENSG00000011422/ENSG00000118194/ENSG00000140279/ENSG00000023909/ENSG00000169896/ENSG00000115602/ENSG00000169252/ENSG00000057149/ENSG00000069702/ENSG00000196611/ENSG00000138696/ENSG00000115008/ENSG00000117525/ENSG00000136244/ENSG00000197405/ENSG00000148926/ENSG00000115604/ENSG00000169194/ENSG00000140465 SERPINE1/STAT1/SERPINA1/TNFRSF14/MAF/TREM1/CX3CL1/LAMA5/SMAD3/MMP9/FBXO32/PLAUR/TNNT2/DUOX2/GCLM/ITGAM/IL1RL1/ADRB2/SERPINB3/TGFBR3/MMP1/BMPR1B/IL1A/F3/IL6/C5AR1/ADM/IL18R1/IL13/CYP1A1 5054/6772/5265/8764/4094/54210/6376/3911/4088/4318/114907/5329/7139/50506/2730/3684/9173/154/6317/7049/4312/658/3552/2152/3569/728/133/8809/3596/1543 30 11 ENSG00000130702/ENSG00000166949/ENSG00000156804/ENSG00000118194/ENSG00000140279/ENSG00000169252/ENSG00000057149/ENSG00000069702/ENSG00000117525/ENSG00000148926/ENSG00000140465 19 ENSG00000106366/ENSG00000115415/ENSG00000197249/ENSG00000157873/ENSG00000178573/ENSG00000124731/ENSG00000006210/ENSG00000100985/ENSG00000011422/ENSG00000023909/ENSG00000169896/ENSG00000115602/ENSG00000196611/ENSG00000138696/ENSG00000115008/ENSG00000136244/ENSG00000197405/ENSG00000115604/ENSG00000169194 DOID:1492 eye and adnexa disease 47/433 430/6411 0.000566812662509527 0.0289074457879859 ENSG00000234745/ENSG00000142227/ENSG00000106366/ENSG00000183876/ENSG00000077942/ENSG00000049130/ENSG00000115415/ENSG00000183770/ENSG00000129038/ENSG00000122691/ENSG00000069667/ENSG00000197249/ENSG00000150627/ENSG00000146674/ENSG00000178573/ENSG00000092969/ENSG00000144810/ENSG00000136450/ENSG00000115414/ENSG00000204390/ENSG00000149131/ENSG00000239713/ENSG00000120738/ENSG00000000971/ENSG00000100985/ENSG00000124762/ENSG00000011422/ENSG00000100234/ENSG00000169252/ENSG00000166165/ENSG00000184292/ENSG00000135437/ENSG00000196611/ENSG00000067082/ENSG00000115008/ENSG00000186765/ENSG00000117525/ENSG00000136244/ENSG00000211445/ENSG00000117115/ENSG00000119630/ENSG00000105974/ENSG00000119699/ENSG00000239732/ENSG00000148926/ENSG00000169194/ENSG00000140465 HLA-B/EMP3/SERPINE1/ARSI/FBLN1/KITLG/STAT1/FOXL2/LOXL1/TWIST1/RORA/SERPINA1/WDR17/IGFBP3/MAF/TGFB2/COL8A1/SRSF1/FN1/HSPA1L/SERPING1/APOBEC3G/EGR1/CFH/MMP9/CDKN1A/PLAUR/TIMP3/ADRB2/CKB/TACSTD2/RDH5/MMP1/KLF6/IL1A/FSCN2/F3/IL6/GPX3/PADI2/PGF/CAV1/TGFB3/TLR9/ADM/IL13/CYP1A1 3106/2014/5054/340075/2192/4254/6772/668/4016/7291/6095/5265/116966/3486/4094/7042/1295/6426/2335/3305/710/60489/1958/3075/4318/1026/5329/7078/154/1152/4070/5959/4312/1316/3552/25794/2152/3569/2878/11240/5228/857/7043/54106/133/3596/1543 47 24 ENSG00000183876/ENSG00000077942/ENSG00000183770/ENSG00000129038/ENSG00000069667/ENSG00000146674/ENSG00000092969/ENSG00000204390/ENSG00000120738/ENSG00000100234/ENSG00000169252/ENSG00000166165/ENSG00000184292/ENSG00000135437/ENSG00000067082/ENSG00000186765/ENSG00000117525/ENSG00000211445/ENSG00000117115/ENSG00000105974/ENSG00000119699/ENSG00000239732/ENSG00000148926/ENSG00000140465 23 ENSG00000234745/ENSG00000142227/ENSG00000106366/ENSG00000049130/ENSG00000115415/ENSG00000122691/ENSG00000197249/ENSG00000150627/ENSG00000178573/ENSG00000144810/ENSG00000136450/ENSG00000115414/ENSG00000149131/ENSG00000239713/ENSG00000000971/ENSG00000100985/ENSG00000124762/ENSG00000011422/ENSG00000196611/ENSG00000115008/ENSG00000136244/ENSG00000119630/ENSG00000169194 DOID:3082 interstitial lung disease 20/433 135/6411 0.0006665972612874 0.0317300296372802 ENSG00000122691/ENSG00000197249/ENSG00000146674/ENSG00000124731/ENSG00000181104/ENSG00000145147/ENSG00000100985/ENSG00000184371/ENSG00000100234/ENSG00000116701/ENSG00000065361/ENSG00000057149/ENSG00000196611/ENSG00000115008/ENSG00000104371/ENSG00000136244/ENSG00000105974/ENSG00000239732/ENSG00000164683/ENSG00000169194 TWIST1/SERPINA1/IGFBP3/TREM1/F2R/SLIT2/MMP9/CSF1/TIMP3/NCF2/ERBB3/SERPINB3/MMP1/IL1A/DKK4/IL6/CAV1/TLR9/HEY1/IL13 7291/5265/3486/54210/2149/9353/4318/1435/7078/4688/2065/6317/4312/3552/27121/3569/857/54106/23462/3596 20 9 ENSG00000146674/ENSG00000181104/ENSG00000145147/ENSG00000100234/ENSG00000116701/ENSG00000065361/ENSG00000057149/ENSG00000105974/ENSG00000239732 11 ENSG00000122691/ENSG00000197249/ENSG00000124731/ENSG00000100985/ENSG00000184371/ENSG00000196611/ENSG00000115008/ENSG00000104371/ENSG00000136244/ENSG00000164683/ENSG00000169194 DOID:0050339 commensal bacterial infectious disease 8/433 31/6411 0.000802742511211954 0.0346908701718099 ENSG00000115415/ENSG00000149131/ENSG00000000971/ENSG00000182782/ENSG00000169896/ENSG00000169403/ENSG00000117525/ENSG00000136244 STAT1/SERPING1/CFH/HCAR2/ITGAM/PTAFR/F3/IL6 6772/710/3075/338442/3684/5724/2152/3569 8 2 ENSG00000182782/ENSG00000117525 6 ENSG00000115415/ENSG00000149131/ENSG00000000971/ENSG00000169896/ENSG00000169403/ENSG00000136244 DOID:0050155 sensory system disease 50/433 474/6411 0.000856583116965813 0.0346908701718099 ENSG00000234745/ENSG00000142227/ENSG00000106366/ENSG00000183876/ENSG00000077942/ENSG00000049130/ENSG00000115415/ENSG00000183770/ENSG00000129038/ENSG00000122691/ENSG00000069667/ENSG00000146648/ENSG00000121742/ENSG00000197249/ENSG00000150627/ENSG00000146674/ENSG00000178573/ENSG00000092969/ENSG00000144810/ENSG00000136450/ENSG00000115414/ENSG00000204390/ENSG00000149131/ENSG00000239713/ENSG00000120738/ENSG00000000971/ENSG00000100985/ENSG00000124762/ENSG00000011422/ENSG00000100234/ENSG00000169252/ENSG00000166165/ENSG00000184292/ENSG00000135437/ENSG00000196611/ENSG00000067082/ENSG00000113916/ENSG00000115008/ENSG00000186765/ENSG00000117525/ENSG00000136244/ENSG00000211445/ENSG00000117115/ENSG00000119630/ENSG00000105974/ENSG00000119699/ENSG00000239732/ENSG00000148926/ENSG00000169194/ENSG00000140465 HLA-B/EMP3/SERPINE1/ARSI/FBLN1/KITLG/STAT1/FOXL2/LOXL1/TWIST1/RORA/EGFR/GJB6/SERPINA1/WDR17/IGFBP3/MAF/TGFB2/COL8A1/SRSF1/FN1/HSPA1L/SERPING1/APOBEC3G/EGR1/CFH/MMP9/CDKN1A/PLAUR/TIMP3/ADRB2/CKB/TACSTD2/RDH5/MMP1/KLF6/BCL6/IL1A/FSCN2/F3/IL6/GPX3/PADI2/PGF/CAV1/TGFB3/TLR9/ADM/IL13/CYP1A1 3106/2014/5054/340075/2192/4254/6772/668/4016/7291/6095/1956/10804/5265/116966/3486/4094/7042/1295/6426/2335/3305/710/60489/1958/3075/4318/1026/5329/7078/154/1152/4070/5959/4312/1316/604/3552/25794/2152/3569/2878/11240/5228/857/7043/54106/133/3596/1543 50 27 ENSG00000183876/ENSG00000077942/ENSG00000183770/ENSG00000129038/ENSG00000069667/ENSG00000146648/ENSG00000121742/ENSG00000146674/ENSG00000092969/ENSG00000204390/ENSG00000120738/ENSG00000100234/ENSG00000169252/ENSG00000166165/ENSG00000184292/ENSG00000135437/ENSG00000067082/ENSG00000113916/ENSG00000186765/ENSG00000117525/ENSG00000211445/ENSG00000117115/ENSG00000105974/ENSG00000119699/ENSG00000239732/ENSG00000148926/ENSG00000140465 23 ENSG00000234745/ENSG00000142227/ENSG00000106366/ENSG00000049130/ENSG00000115415/ENSG00000122691/ENSG00000197249/ENSG00000150627/ENSG00000178573/ENSG00000144810/ENSG00000136450/ENSG00000115414/ENSG00000149131/ENSG00000239713/ENSG00000000971/ENSG00000100985/ENSG00000124762/ENSG00000011422/ENSG00000196611/ENSG00000115008/ENSG00000136244/ENSG00000119630/ENSG00000169194 DOID:2921 glomerulonephritis 12/433 63/6411 0.000874559752230501 0.0346908701718099 ENSG00000106366/ENSG00000049130/ENSG00000146674/ENSG00000178573/ENSG00000163661/ENSG00000166949/ENSG00000000971/ENSG00000100985/ENSG00000153246/ENSG00000130402/ENSG00000136244/ENSG00000151490 SERPINE1/KITLG/IGFBP3/MAF/PTX3/SMAD3/CFH/MMP9/PLA2R1/ACTN4/IL6/PTPRO 5054/4254/3486/4094/5806/4088/3075/4318/22925/81/3569/5800 12 4 ENSG00000146674/ENSG00000166949/ENSG00000153246/ENSG00000130402 8 ENSG00000106366/ENSG00000049130/ENSG00000178573/ENSG00000163661/ENSG00000000971/ENSG00000100985/ENSG00000136244/ENSG00000151490 DOID:9563 bronchiectasis 5/433 13/6411 0.00112230090534968 0.0406909551917277 ENSG00000197249/ENSG00000100985/ENSG00000169252/ENSG00000196611/ENSG00000166828 SERPINA1/MMP9/ADRB2/MMP1/SCNN1G 5265/4318/154/4312/6340 5 1 ENSG00000169252 4 ENSG00000197249/ENSG00000100985/ENSG00000196611/ENSG00000166828 DOID:5614 eye disease 45/433 421/6411 0.00119194664878867 0.0406909551917277 ENSG00000234745/ENSG00000142227/ENSG00000106366/ENSG00000183876/ENSG00000077942/ENSG00000049130/ENSG00000115415/ENSG00000129038/ENSG00000122691/ENSG00000069667/ENSG00000197249/ENSG00000150627/ENSG00000146674/ENSG00000178573/ENSG00000092969/ENSG00000144810/ENSG00000115414/ENSG00000204390/ENSG00000149131/ENSG00000239713/ENSG00000120738/ENSG00000000971/ENSG00000100985/ENSG00000124762/ENSG00000011422/ENSG00000100234/ENSG00000169252/ENSG00000166165/ENSG00000184292/ENSG00000135437/ENSG00000196611/ENSG00000067082/ENSG00000115008/ENSG00000186765/ENSG00000117525/ENSG00000136244/ENSG00000211445/ENSG00000117115/ENSG00000119630/ENSG00000105974/ENSG00000119699/ENSG00000239732/ENSG00000148926/ENSG00000169194/ENSG00000140465 HLA-B/EMP3/SERPINE1/ARSI/FBLN1/KITLG/STAT1/LOXL1/TWIST1/RORA/SERPINA1/WDR17/IGFBP3/MAF/TGFB2/COL8A1/FN1/HSPA1L/SERPING1/APOBEC3G/EGR1/CFH/MMP9/CDKN1A/PLAUR/TIMP3/ADRB2/CKB/TACSTD2/RDH5/MMP1/KLF6/IL1A/FSCN2/F3/IL6/GPX3/PADI2/PGF/CAV1/TGFB3/TLR9/ADM/IL13/CYP1A1 3106/2014/5054/340075/2192/4254/6772/4016/7291/6095/5265/116966/3486/4094/7042/1295/2335/3305/710/60489/1958/3075/4318/1026/5329/7078/154/1152/4070/5959/4312/1316/3552/25794/2152/3569/2878/11240/5228/857/7043/54106/133/3596/1543 45 23 ENSG00000183876/ENSG00000077942/ENSG00000129038/ENSG00000069667/ENSG00000146674/ENSG00000092969/ENSG00000204390/ENSG00000120738/ENSG00000100234/ENSG00000169252/ENSG00000166165/ENSG00000184292/ENSG00000135437/ENSG00000067082/ENSG00000186765/ENSG00000117525/ENSG00000211445/ENSG00000117115/ENSG00000105974/ENSG00000119699/ENSG00000239732/ENSG00000148926/ENSG00000140465 22 ENSG00000234745/ENSG00000142227/ENSG00000106366/ENSG00000049130/ENSG00000115415/ENSG00000122691/ENSG00000197249/ENSG00000150627/ENSG00000178573/ENSG00000144810/ENSG00000115414/ENSG00000149131/ENSG00000239713/ENSG00000000971/ENSG00000100985/ENSG00000124762/ENSG00000011422/ENSG00000196611/ENSG00000115008/ENSG00000136244/ENSG00000119630/ENSG00000169194 DOID:1555 urticaria 8/433 33/6411 0.00125378293307844 0.0406909551917277 ENSG00000234745/ENSG00000049130/ENSG00000206337/ENSG00000100985/ENSG00000169252/ENSG00000117525/ENSG00000132965/ENSG00000169194 HLA-B/KITLG/HCP5/MMP9/ADRB2/F3/ALOX5AP/IL13 3106/4254/10866/4318/154/2152/241/3596 8 2 ENSG00000169252/ENSG00000117525 6 ENSG00000234745/ENSG00000049130/ENSG00000206337/ENSG00000100985/ENSG00000132965/ENSG00000169194 DOID:2596 larynx cancer 8/433 33/6411 0.00125378293307844 0.0406909551917277 ENSG00000178934/ENSG00000100097/ENSG00000100985/ENSG00000124762/ENSG00000196611/ENSG00000136244/ENSG00000105974/ENSG00000169194 LGALS7B/LGALS1/MMP9/CDKN1A/MMP1/IL6/CAV1/IL13 653499/3956/4318/1026/4312/3569/857/3596 8 1 ENSG00000105974 7 ENSG00000178934/ENSG00000100097/ENSG00000100985/ENSG00000124762/ENSG00000196611/ENSG00000136244/ENSG00000169194 DOID:2723 dermatitis 19/433 134/6411 0.00154232221943744 0.0478790462903622 ENSG00000049130/ENSG00000128342/ENSG00000072274/ENSG00000157873/ENSG00000006210/ENSG00000166949/ENSG00000100985/ENSG00000133710/ENSG00000124762/ENSG00000011422/ENSG00000115602/ENSG00000011201/ENSG00000169035/ENSG00000163207/ENSG00000115008/ENSG00000136244/ENSG00000064300/ENSG00000169194/ENSG00000162924 KITLG/LIF/TFRC/TNFRSF14/CX3CL1/SMAD3/MMP9/SPINK5/CDKN1A/PLAUR/IL1RL1/ANOS1/KLK7/IVL/IL1A/IL6/NGFR/IL13/REL 4254/3976/7037/8764/6376/4088/4318/11005/1026/5329/9173/3730/5650/3713/3552/3569/4804/3596/5966 19 6 ENSG00000072274/ENSG00000166949/ENSG00000133710/ENSG00000169035/ENSG00000163207/ENSG00000162924 13 ENSG00000049130/ENSG00000128342/ENSG00000157873/ENSG00000006210/ENSG00000100985/ENSG00000124762/ENSG00000011422/ENSG00000115602/ENSG00000011201/ENSG00000115008/ENSG00000136244/ENSG00000064300/ENSG00000169194 DOID:1116 pertussis 7/433 27/6411 0.00165725547563828 0.049303350400239 ENSG00000115415/ENSG00000149131/ENSG00000000971/ENSG00000182782/ENSG00000169896/ENSG00000169403/ENSG00000136244 STAT1/SERPING1/CFH/HCAR2/ITGAM/PTAFR/IL6 6772/710/3075/338442/3684/5724/3569 7 1 ENSG00000182782 6 ENSG00000115415/ENSG00000149131/ENSG00000000971/ENSG00000169896/ENSG00000169403/ENSG00000136244 DOID:3083 chronic obstructive pulmonary disease 23/433 177/6411 0.00172708946016139 0.0493256749822094 ENSG00000106366/ENSG00000115415/ENSG00000197249/ENSG00000124731/ENSG00000166949/ENSG00000100985/ENSG00000156804/ENSG00000011422/ENSG00000118194/ENSG00000140279/ENSG00000023909/ENSG00000169896/ENSG00000115602/ENSG00000169252/ENSG00000069702/ENSG00000196611/ENSG00000115008/ENSG00000117525/ENSG00000136244/ENSG00000197405/ENSG00000148926/ENSG00000169194/ENSG00000140465 SERPINE1/STAT1/SERPINA1/TREM1/SMAD3/MMP9/FBXO32/PLAUR/TNNT2/DUOX2/GCLM/ITGAM/IL1RL1/ADRB2/TGFBR3/MMP1/IL1A/F3/IL6/C5AR1/ADM/IL13/CYP1A1 5054/6772/5265/54210/4088/4318/114907/5329/7139/50506/2730/3684/9173/154/7049/4312/3552/2152/3569/728/133/3596/1543 23 9 ENSG00000166949/ENSG00000156804/ENSG00000118194/ENSG00000140279/ENSG00000169252/ENSG00000069702/ENSG00000117525/ENSG00000148926/ENSG00000140465 14 ENSG00000106366/ENSG00000115415/ENSG00000197249/ENSG00000124731/ENSG00000100985/ENSG00000011422/ENSG00000023909/ENSG00000169896/ENSG00000115602/ENSG00000196611/ENSG00000115008/ENSG00000136244/ENSG00000197405/ENSG00000169194