Hirschfield et al. 10.1073/pnas.0503202102.

Supporting Information

Files in this Data Supplement:

Supporting Table 3




Table 3. Serum cholesterol and triglyceride concentrations in apoE-/- and apoE+/+ mice with and without transgenic human CRP

Age

Serum concentrations, mg/liter

ApoE+/+

ApoE+/+-hCRP+

ApoE-/-

ApoE-/--hCRP+

 

Cholesterol

Triglycerides

Cholesterol

Triglycerides

Cholesterol

Triglycerides

Cholesterol

Triglycerides

 

 

 

 

 

8 weeks

2.68 (2.15-3.45)

1.0 (0.85-1.07)

2.23 (1.80-3.24)

0.94 (0.54-1.20)

10.64 (6.63-22.43)

1.44 (0.70-3.56)

10.17 (6.72-16.80)

1.68 (0.89-6.12)

 

n

 = 5

n

 = 5

n

 = 12

n

 = 12

n

 = 32

n

 = 32

n

 = 25

n

 = 25

12 weeks

2.64 (1.97-3.74)

0.81 (0.64-1.31)

2.46 (1.49-3.80)

0.88 (0.49-1.25)

12.03 (7.60-20.60)

1.34 (0.70-3.47)

13.24 (8.18-21.39)

1.57 (0.81-3.97)

 

n

 = 8

n

 = 8

n

 = 20

n

 = 20

n

 = 29

n

 = 29

n

 = 24

n

 = 24

16 weeks

2.79 (1.61-3.04)

0.94 (0.54-1.60)

2.51 (1.22-3.54)

0.97 (0.52-1.51

11.64 (3.05-17.42)

1.34 (0.72-2.75)

12.41 (7.51-19.38)

1.55 (0.74-2.99)

 

n

 = 11

n

 = 11

n

 = 24)

n

 = 24

n

 = 30

n

 = 30

n

 = 24

n

 = 24

20 weeks

3.25 (2.56-3.51)

1.12 (0.92-1.77)

2.89 (1.49-3.44)

0.98 (0.56-1.55)

13.05 (7.79-18.66)

1.80 (0.79-3.19)

13.57 (5.47-19.70)

1.74 (0.90-3.50)

 

n

 = 9

n

 = 9

n

 = 20

n

 = 20

n

 = 38

n

 = 38

n

 = 38

n

 = 38

52 weeks

 

 

 

 

17.61 (9.37-20.54)

1.93 (1.35-2.60)

15.13 (4.81-19.75)

1.78 (1.26-4.11)

 

 

 

 

 

n

 = 20

n

 = 20

n

 = 16

n

 = 16

56 weeks

 

 

 

 

16.26 (9.49-20.59)

1.99 (1.17-3.32)

15.80 (10.08-20.59)

2.15 (1.45-3.43)

 

 

 

 

 

n

 = 15

n

 = 15

n

 = 13

n

 = 13

Concentrations are presented as median (range).