The cysteine-rich region of respiratory syncytial virus attachment protein inhibits innate immunity elicited by the virus and endotoxin -- Polack et al. 102 (25): 8996 Data Supplement - HTML Page - index.htslp -- Proceedings of the National Academy of Sciences

Polack et al. 10.1073/pnas.0409478102.

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Fig. 6. Scheme of the structure of respiratory syncytial virus (RSV) glycoprotein-based on RSV A2 strain (1). Cysteine residues are indicated with filled circles and the disulfide bonding pattern with dotted lines. Also shown are the 13-aa segment and the domain that has similarity to the CX3C chemokine fractalkine (1, 2).

1. Collins, P. L., Chanock, R. M. & Murphy, B. R. (2001) in Fields Virology, eds. Knipe, D. M. & Howley, P. M. (Lippincott Williams and Wilkins, Philadelphia), pp. 1443-1486.

2. Tripp, R .A., Jones, L. P., Haynes, L. M., Zheng, H., Murphy, P. M. & Anderson, L. J. (2001) Nat Immunol.2, 732-738.

Fig. 7.
Modulation of Toll-like receptor 2 (TLR2)- and TLR9-mediated inflammatory responses. Purified human monocytes were stimulated with PGN or PGN plus glycoprotein (a) and CPG DNA or CpG DNA plus glycoprotein (b). Supernatants were collected 18 h after addition of stimulants. IL-10 was measured by immunoassay. Results are mean ± SEM.