Table 2. Genes regulated in the VTA of Clock mutant mice
AFFY # | Signal | log2 ratio Mut/Cont | P value | Gene | ||
Genes up-regulated in the VTA of Clock mutant mice vs littermate controls | ||||||
103582_r_at | 54.33333 | 1.1 | 0.003903 | RIKEN cDNA 6130401J04 gene | ||
101393_at | 87.66667 | 1.1 | 0.002759 | Annexin A3 | ||
100324_g_at | 216.9 | 1.05 | 8.5E-06 | --- | ||
92247_at | 198 | 1 | 0.007882 | Rho GTPase activating protein 5 | ||
98474_r_at | 76.2 | 0.95 | 0.006026 | TNFa -induced protein 6 | ||
101524_at | 233.0333 | 0.9 | 0.021427 | RIKEN cDNA 2610510D13 gene | ||
99098_at | 1402.733 | 0.9 | 0.003766 | Farnesyl diphosphate synthetase | ||
102703_s_at | 728.1 | 0.9 | 0.006518 | Aquaporin 4 | ||
94143_at | 159.2667 | 0.8 | 0.002703 | Glial fibrillary acidic protein | ||
98770_at | 184.3333 | 0.8 | 0.007123 | Centromere autoantigen C | ||
102885_at | 140.2667 | 0.75 | 1.5E-06 | Synaptobrevin like 1 | ||
94494_at | 268.9667 | 0.75 | 0.01474 | Phenylalanine-tRNA synthetase-like | ||
96731_at | 455.8333 | 0.7 | 0.000156 | RIKEN cDNA 1110001P04 gene | ||
92944_at | 417.9 | 0.7 | 0.000333 | Glutamate receptor, ionotropic, AMPA1 (a 1) | ||
98762_f_at | 59.9 | 0.65 | 0.004006 | Zinc finger protein 97 | ||
103710_at | 119.7667 | 0.65 | 0.000244 | Sequence with weak similarity to protein pir:T14757 (Homo sapiens) | ||
99121_at | 97.2 | 0.65 | 0.00063 | Fragile X mental retardation gene 1, autosomal homolog | ||
102277_at | 134.7 | 0.6 | 0.004991 | Zinc finger protein 26 | ||
100690_at | 2155.1 | 0.6 | 0.000001 | Tyrosine hydroxylase | ||
103569_at | 191.7 | 0.6 | 0.008265 | SH3-domain GRB2-like B1 (endophilin) | ||
101966_s_at | 1049.267 | 0.6 | 0.000145 | Ring finger protein 13 | ||
93039_at | 72.4 | 0.6 | 0.000215 | RIKEN cDNA 1190003P12 gene | ||
160266_r_at | 205.6 | 0.6 | 0.00012 | RIKEN cDNA 1110064N10 gene | ||
93390_g_at | 72.5 | 0.6 | 0.02839 | Prominin 1 | ||
101590_at | 464.8333 | 0.6 | 0.009483 | Lysosomal membrane glycoprotein 2 | ||
100435_at | 489.1667 | 0.6 | 3.65E-05 | Endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2 | ||
95093_at | 85.93333 | 0.55 | 0.021511 | RIKEN cDNA 2610511G16 gene | ||
96885_at | 89.83333 | 0.55 | 0.018079 | RIKEN cDNA 2510015F01 gene | ||
103321_at | 120.8 | 0.55 | 0.007924 | Hypothetical protein B230364F10 | ||
94144_g_at | 603.6667 | 0.55 | 0.004874 | Glial fibrillary acidic protein | ||
103895_at | 568.3333 | 0.55 | 0.014737 | Expressed sequence AW549877 | ||
160678_at | 126.3333 | 0.55 | 0.005337 | EST AI426782 | ||
102704_at | 1646.033 | 0.55 | 3.25E-05 | Aquaporin4 | ||
93909_f_at | 1776.433 | 0.55 | 0.003766 | --- | ||
102872_f_at | 49.5 | 0.5 | 0.01073 | Zinc finger protein51 | ||
160392_at | 228.2333 | 0.5 | 0.003148 | RIKEN cDNA B430110G05 gene | ||
160200_at | 137.7667 | 0.5 | 0.0197 | RIKEN cDNA 3230401D17 gene | ||
97346_at | 80.03333 | 0.5 | 0.003441 | RIKEN cDNA 2610001J05 gene | ||
96068_at | 124.8333 | 0.5 | 0.004627 | RIKEN cDNA 1500034J20 gene | ||
96295_at | 1711.767 | 0.5 | 0.024019 | Phosphoserine aminotransferase1 | ||
94915_at | 421.5 | 0.5 | 9.25E-05 | Peptidylprolyl isomeraseB | ||
97853_at | 179.9667 | 0.5 | 0.021292 | PC4 and SFRS1 interacting protein2 | ||
94459_at | 183.6667 | 0.5 | 0.009662 | Mus musculus cDNA clone MGC:36861 IMAGE:4460168, complete cds | ||
94975_at | 242.2 | 0.5 | 0.010096 | Iron responsive element-binding protein2 | ||
97204_s_at | 246.2333 | 0.5 | 0.000121 | DnaJ (Hsp40) homolog, subfamily D, member 1 | ||
92257_at | 204.7 | 0.5 | 0.000788 | Circadian locomoter output cycles kaput | ||
104135_at | 803.4333 | 0.5 | 0.000784 | ADP-ribosylation factor-like3 | ||
101781_f_at | 138.2333 | 0.5 | 0.008955 | --- | ||
101588_at | 92.03333 | 0.45 | 0.000771 | Solute carrier family 16 (monocarboxylic acid transporters), member 1 | ||
95502_at | 1166.667 | 0.45 | 0.001427 | Sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae) | ||
95387_f_at | 211.9333 | 0.45 | 0.025122 | Semaphorin4B | ||
101489_at | 1285.333 | 0.45 | 0.007664 | S -adenosylmethionine decarboxylase1 | ||
97506_at | 170.7 | 0.45 | 0.017044 | Ring finger protein2 | ||
103257_at | 395.0667 | 0.45 | 0.01065 | RIKEN cDNA C730036B01 gene | ||
95288_i_at | 260.3667 | 0.45 | 0.00641 | RIKEN cDNA C330012F17 gene | ||
94895_at | 175.2 | 0.45 | 0.000823 | RIKEN cDNA 9430020E02 gene | ||
102052_at | 135.6 | 0.45 | 0.00279 | RIKEN cDNA 1300003D03 gene | ||
99445_at | 92.46667 | 0.45 | 0.006568 | RIKEN cDNA 1110028E10 gene | ||
100711_at | 1413.7 | 0.45 | 0.001477 | Ribosomal protein L10A | ||
92379_f_at | 873.2333 | 0.45 | 0.000621 | Protein tyrosine phosphatase, receptor type, Z polypeptide 1 | ||
93485_at | 1217.3 | 0.45 | 0.001033 | Protein tyrosine phosphatase, receptor type, D | ||
97989_at | 221.9 | 0.45 | 0.006547 | Protein phosphatase 3, catalytic subunit, b isoform | ||
103791_at | 102.8333 | 0.45 | 0.00359 | NMDA receptor-regulated gene1 | ||
92876_at | 77.16667 | 0.45 | 0.017808 | NADH dehydrogenase (ubiquinone) Fe-S protein 4 | ||
101946_at | 230.3 | 0.45 | 0.000939 | Lysophospholipase1 | ||
94214_at | 327.4 | 0.45 | 0.022215 | Fatty acid-binding protein 3, muscle and heart | ||
93885_g_at | 121.0333 | 0.45 | 0.025394 | Endomucin | ||
98025_at | 992.1667 | 0.45 | 0.001676 | Ecotropic viral integration site2 | ||
98132_at | 541.5333 | 0.45 | 0.000759 | Cytochrome c, somatic | ||
93057_at | 716.3 | 0.45 | 0.0197 | Basic transcription factor3 | ||
104330_g_at | 157.8 | 0.4 | 0.006429 | SWI/SNF related, matrix associated, actin-dependent regulator of chromatin, subfamily f, member 1 | ||
101906_at | 101.6667 | 0.4 | 0.02726 | SMC4 structural maintenance of chromosomes 4-like 1 (yeast) | ||
92579_at | 282 | 0.4 | 0.000837 | Sjogren syndrome antigenB | ||
99185_at | 352.4333 | 0.4 | 0.005913 | RIKEN cDNA 2810443J12 gene | ||
96688_at | 127.1 | 0.4 | 0.000385 | RIKEN cDNA 2610318G18 gene | ||
98491_at | 503.4333 | 0.4 | 0.025206 | RIKEN cDNA 2610313E07 gene | ||
96672_at | 577.3333 | 0.4 | 0.000193 | RIKEN cDNA 2300002F06 gene | ||
97874_at | 520.8667 | 0.4 | 0.000331 | RIKEN cDNA 1500032D16 gene | ||
104386_f_at | 1440.9 | 0.4 | 0.00623 | RIKEN cDNA 1110004F14 gene | ||
94913_at | 627.1 | 0.4 | 2.05E-05 | Ras-GTPase-activating protein (GAP<120>) SH3-domain-binding protein 2 | ||
102395_at | 567.4333 | 0.4 | 0.001519 | Peripheral myelin protein | ||
96082_at | 550.6333 | 0.4 | 0.001034 | Mitochondrial ribosomal protein L30 | ||
93078_at | 682.5667 | 0.4 | 0.001898 | Lymphocyte antigen 6 complex, locus A | ||
95359_at | 6454.5 | 0.4 | 0.001108 | Heat-shock protein 1, b | ||
98026_g_at | 1335.167 | 0.4 | 0.001191 | Ecotropic viral integration site2 | ||
99128_at | 1791.5 | 0.4 | 0.002592 | ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit | ||
104602_at | 177.4 | 0.35 | 0.01441 | Wiskott-Aldrich syndrome protein interacting protein | ||
103328_at | 212.8333 | 0.35 | 0.010525 | TRAF family member-associated Nf-k B activator | ||
103074_f_at | 366.7667 | 0.35 | 0.008492 | TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor | ||
93471_at | 515.7 | 0.35 | 0.001094 | Solute carrier family 4, sodium bicarbonate cotransporter, member 7 | ||
99179_at | 408 | 0.35 | 0.008499 | RIKEN cDNA 3010002G01 gene | ||
95743_at | 1290.2 | 0.35 | 0.007723 | RIKEN cDNA 2310050K10 gene | ||
103567_at | 485.5333 | 0.35 | 0.022124 | RIKEN cDNA 2010313D22 gene | ||
93580_at | 1174.767 | 0.35 | 0.009042 | Pumilio 2 (Drosophila) | ||
101992_at | 841.8333 | 0.35 | 0.020526 | Proteasome (prosome, macropain) subunit b type 6 | ||
93623_at | 88.86667 | 0.35 | 0.01303 | Dystrophin, muscular dystrophy | ||
96059_at | 299.5667 | 0.35 | 0.002777 | DNA segment, Chr 4, ERATO Doi 786, expressed | ||
160655_at | 206.0667 | 0.35 | 0.009076 | CarboxypeptidaseD | ||
92575_at | 544.2333 | 0.35 | 0.019418 | Aryl-hydrocarbon receptor-interacting protein | ||
103745_at | 224.2 | 0.3 | 0.015185 | Sorting nexin13 | ||
104709_at | 1290.333 | 0.3 | 0.005919 | SEC23A (S. cerevisiae) | ||
97315_at | 286.8333 | 0.3 | 0.016868 | RIKEN cDNA 2610028L19 gene | ||
98039_at | 412.4333 | 0.3 | 0.012747 | RIKEN cDNA 2410015M20 gene | ||
98397_at | 112.3667 | 0.3 | 0.025333 | RIKEN cDNA 1700030G05 gene | ||
98089_at | 95.36667 | 0.3 | 0.02404 | RIKEN cDNA 1190005P17 gene | ||
104725_at | 702.6667 | 0.3 | 0.022716 | Ras homolog gene family, member Q | ||
96632_at | 2964.9 | 0.3 | 0.00811 | Mortality factor 4 like2 | ||
95003_at | 422.2667 | 0.3 | 0.02054 | Metallothionein-I activator | ||
92816_r_at | 284.0333 | 0.3 | 0.022873 | Eukaryotic translation initiation factor 4A1 | ||
94766_at | 8905.767 | 0.3 | 0.002975 | Eukaryotic translation elongation factor 1 a 1 | ||
97248_at | 1545.5 | 0.3 | 0.004408 | Diazepam-binding inhibitor | ||
160326_at | 231.3 | 0.3 | 0.026864 | Carnitine deficiency-associated gene expressed in ventricle 3 | ||
98079_at | 565.1 | 0.3 | 0.002753 | Carbonic anhydrase14 | ||
98254_f_at | 6327.333 | 0.3 | 0.006856 | --- | ||
Genes down-regulated in the VTA of Clock mutant mice vs littermate controls | ||||||
92501_s_at | 69.83333 | -1.4 | 0.97294 | Pleiomorphic adenoma gene-like 1 | ||
160841_at | 173.4667 | -1.2 | 0.999696 | D site albumin promoter-binding protein | ||
92925_at | 119.4667 | -1 | 0.999957 | CCAAT/enhancer binding protein (C/EBP), b | ||
160878_at | 190.9333 | -0.75 | 0.999464 | Block of proliferation 1 | ||
101007_at | 169.6667 | -0.75 | 0.980898 | MAP kinase-interacting serine/threonine kinase 2 | ||
99390_at | 65.56667 | -0.75 | 0.99751 | Wingless-related MMTV integration site 5A | ||
93619_at | 71.06667 | -0.7 | 0.96911 | Period homolog 1 (Drosophila) | ||
96055_at | 1593.867 | -0.65 | 0.999982 | Cholecystokinin | ||
104685_g_at | 132.8 | -0.65 | 0.9971 | Glutamate receptor, ionotropic, NMDA1 (z 1) | ||
98008_at | 1678.2 | -0.6 | 1 | chemokine (C-X3-C motif) ligand 1 | ||
160965_at | 143.3333 | -0.6 | 0.996315 | EST AA793972 | ||
92749_at | 983.2667 | -0.6 | 0.999965 | GABA-A receptor, subunit b 1 | ||
102313_at | 152 | -0.6 | 0.999829 | GTP cyclohydrolase 1 | ||
92180_at | 373.6333 | -0.6 | 0.997895 | H1 histone family, member X | ||
97336_at | 606.6333 | -0.55 | 0.99989 | Cathepsin F | ||
94811_s_at | 2635.733 | -0.55 | 0.999625 | General transcription factor II H, polypeptide 1 | ||
104409_at | 268.7 | -0.55 | 0.999761 | Glutamate receptor, ionotropic, kainate 5 (g 2) | ||
104686_at | 192.4 | -0.55 | 0.999902 | Glutamate receptor, ionotropic, NMDA1 (z 1) | ||
93694_at | 21.06667 | -0.55 | 0.999992 | Period 2 | ||
104269_at | 487.3333 | -0.55 | 0.985713 | Synaptotagmin 5 | ||
96637_at | 164.4 | -0.55 | 0.98255 | TBC1 domain family, member 1 | ||
96069_at | 538.6667 | -0.5 | 0.99538 | Aldo-keto reductase family 7, member A5 (aflatoxin aldehyde reductase) | ||
100439_i_at | 1239.333 | -0.5 | 0.999979 | Ankyrin 1, erythroid | ||
97925_at | 393.0333 | -0.5 | 0.999994 | Casein kinase 1, e | ||
102196_at | 213.2 | -0.5 | 0.999884 | Guanine nucleotide binding protein, a 11 | ||
96911_at | 1542.3 | -0.5 | 0.999921 | Guanine nucleotide binding protein, b 2 | ||
93019_at | 525.3333 | -0.5 | 0.999781 | H2A histone family, member X | ||
92908_at | 291.7 | -0.5 | 0.999921 | Human immunodeficiency virus type I enhancer-binding protein 1 | ||
99109_at | 100.1667 | -0.5 | 0.983275 | Immediate early response 2 | ||
101947_at | 349.5667 | -0.5 | 0.999873 | Neighbor of A-kinase anchoring protein 95 | ||
94932_at | 711.8333 | -0.5 | 0.999993 | Platelet derived growth factor, a | ||
93347_at | 1243.533 | -0.5 | 0.998228 | RAB24, member RAS oncogene family | ||
161243_f_at | 598.6 | -0.5 | 0.999764 | RIKEN cDNA 0910001L24 gene | ||
99514_at | 1031.5 | -0.45 | 0.999879 | Brain expressed myelocytomatosis oncogene | ||
104589_at | 367.8333 | -0.45 | 0.998384 | Expressed sequence C80913 | ||
99872_s_at | 1897.567 | -0.45 | 0.999993 | Ferritin light chain1 | ||
95489_at | 385.7 | -0.45 | 0.990941 | Flightless I homolog (Drosophila) | ||
160335_at | 290 | -0.45 | 0.979469 | Glutamate-cysteine ligase, modifier subunit | ||
96656_at | 356.4333 | -0.45 | 0.99846 | Golgi reassembly stacking protein 1 | ||
97227_at | 243.4333 | -0.45 | 0.99992 | Guanine nucleotide-binding protein, a 12 | ||
161214_r_at | 1172.333 | -0.45 | 0.99913 | Hypothetical protein MGC47434 | ||
160820_at | 1006.4 | -0.45 | 0.997023 | Immunoglobulin superfamily, member8 | ||
160417_at | 1143.633 | -0.45 | 0.992719 | Kinesin family member5B | ||
93642_at | 457.3667 | -0.45 | 0.999648 | Longevity assurance homolog 1 (S. cerevisiae) | ||
104554_at | 327 | -0.45 | 0.996066 | Nuclear receptor subfamily 2, group F, member 6 | ||
160412_at | 91.03333 | -0.45 | 0.991294 | Programmed cell death2 | ||
103501_at | 1507.467 | -0.45 | 0.999674 | Purine rich element-binding protein A | ||
97104_g_at | 836.1333 | -0.45 | 0.999993 | RIKEN cDNA 0610038L10 gene | ||
94958_at | 133.5667 | -0.45 | 0.992878 | RIKEN cDNA 1110013L07 gene | ||
94925_at | 193.5667 | -0.45 | 0.994772 | RIKEN cDNA 1810055D05 gene | ||
97722_at | 254.5333 | -0.45 | 0.976877 | Signal sequence receptor, a | ||
103910_at | 382.2 | -0.4 | 0.997959 | --- | ||
97263_s_at | 946.5 | -0.4 | 0.980606 | Casein kinase 1, d | ||
95619_at | 114.8667 | -0.4 | 0.999132 | Chaperonin subunit 7 (h ) | ||
92223_at | 541.2667 | -0.4 | 0.999346 | Complement component 1, q subcomponent, g polypeptide | ||
162469_r_at | 2395.533 | -0.4 | 0.997532 | Cytochromec-1 | ||
101367_at | 1364.367 | -0.4 | 0.99007 | Dynactin1 | ||
104109_at | 699.9 | -0.4 | 0.999932 | F-box only protein21 | ||
95095_at | 848.3333 | -0.4 | 0.977229 | Flotillin1 | ||
94295_at | 1331.533 | -0.4 | 0.999062 | General transcription factor II I | ||
95566_at | 412.1667 | -0.4 | 0.98559 | Glycosylphosphatidylinositol specific phospholipase D1 | ||
98511_at | 121.1 | -0.4 | 0.978722 | HnRNP-associated with lethal yellow | ||
96741_at | 161.2 | -0.4 | 0.9716 | Mus musculus mRNA for mKIAA1523 protein | ||
97520_s_at | 1922.267 | -0.4 | 0.999896 | Neuronatin | ||
99599_s_at | 2116.233 | -0.4 | 0.999572 | Prostate tumor overexpressed gene 1 | ||
96313_at | 1281.267 | -0.4 | 0.999853 | RAS protein-specific guanine nucleotide-releasing factor 1 | ||
97514_at | 188.5333 | -0.4 | 0.996121 | RIKEN cDNA 1810063B05 gene | ||
104320_at | 1228.233 | -0.4 | 0.992107 | RIKEN cDNA 2310036D04 gene | ||
100633_at | 520.8333 | -0.4 | 0.995761 | RIKEN cDNA 2810484M10 gene | ||
160204_at | 172.5 | -0.4 | 0.987205 | RIKEN cDNA 3110013H01 gene | ||
103220_at | 227.7 | -0.4 | 0.999898 | RIKEN cDNA 5730494G16 gene | ||
160196_at | 492.5667 | -0.4 | 0.979481 | Stromal membrane-associated protein1 | ||
94457_at | 462.2 | -0.4 | 0.998709 | Ubiquitin conjugating enzyme 7 interacting protein 3 | ||
97724_at | 214.7333 | -0.35 | 0.982532 | Cryptochrome 2 (photolyase-like) | ||
101975_at | 890 | -0.35 | 0.999594 | Delta-like 1 homolog (Drosophila) | ||
99150_at | 192.1667 | -0.35 | 0.994637 | Immature colon carcinoma transcript 1 | ||
94516_f_at | 1535.1 | -0.35 | 0.992157 | Preproenkephalin1 | ||
92545_f_at | 2208.4 | -0.35 | 0.997533 | Prostaglandin D2 synthase (brain) | ||
160393_at | 1307.767 | -0.35 | 0.970397 | RIKEN cDNA 4930555L11 gene | ||
92757_at | 614.2333 | -0.35 | 0.999822 | Seizure-related gene6 | ||
101446_at | 153.8333 | -0.35 | 0.99675 | Tumor protein D52-like1 | ||
98617_at | 885.9 | -0.35 | 0.970653 | WW domain-binding protein 11 | ||
102835_at | 295.6 | -0.3 | 0.968314 | Adaptor protein complex AP-2, a 2 subunit | ||
95000_g_at | 81.96667 | -0.3 | 0.986379 | Mus musculus mRNA for hypothetical protein | ||
99449_at | 1003.033 | -0.3 | 0.990248 | Potassium voltage-gated channel, subfamily Q, member 2 | ||
104422_at | 1343.4 | -0.3 | 0.997804 | Protein tyrosine phosphatase, receptor type, N | ||
160240_at | 1132.467 | -0.3 | 0.999811 | RIKEN cDNA 1110003E01 gene | ||
96320_at | 1477.1 | -0.3 | 0.95387 | RIKEN cDNA 2310044H10 gene | ||
104375_at | 3760.567 | -0.3 | 0.980251 | Sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2 | ||
Cell growth or death.
SH3-domain GRB2-likeB1, peripheral myelin protein, ecotropic viral integration site2, mortality factor 4 like 2, block of proliferation 1, brain expressed myelocytomatosis oncogene, programmed cell death 2, platelet-derived growth factor a , pleiomorphic adenoma gene-like 1.Regulation of transcription.
Metallothionein-1 activator; matrix associated actin-dependent regulator of chromatin f1; basic transcription factor 3; ring finger protein 2; Circadian locomotor output cycles kaput; sirtuin 2; aryl-hydrocarbon receptor-interacting protein; zinc finger proteins 26, 51, and 97; centromere autoantigen C; TAF9 RNA polymerase II; H1 histone X; H2A histone X; HIV 1 enhancer-binding protein 1; ankyrin1; CCAAT/enhancer-binding protein b ; D site albumin promoter-binding protein; general transcription factor 2H1; general transcription factor 2I; nuclear receptor 2F6; purine rich element-binding protein A; period 1; period 2; cryptochrome 2.Signal transduction, second messengers.
Protein phosphatase 3 catalytic b , RAS-GTPase-activating protein, RAS homolog Q, r GTPase activating protein 5, ADP-ribosylation factor-like3, TRAF family member-Nfk B activator, protein tyrosine phosphatase receptor D, protein tyrosine phosphatase receptor Z1, endothelial differentiation G-protein coupled receptor 2, G-proteins a 11, a 12, b 2, casein kinase 1 d , casein kinase 1 e , MAP kinase-interacting serine/threonine kinase 2, RAB24, RAS protein specific guanine nucleotide-releasing factor 1, wingless-related MMTV integration site 5A, protein tyrosine phosphatase receptor N.RNA binding, translational control, protein synthesis.
Eukaryotic translation initiation factor 4A1, fragil X mental retardation gene 1 homolog, pumilio 2, Sjogren syndrome antigen B, lysosomal membrane glycoprotein 2, phenylalanine-tRNA synthetase-like, eukaryotic translation elongation factor 1 a 1, mitochondrial ribosomal protein L30, ribosomal protein L10A, iron responsive element-binding protein 2, hnRNP-associated with lethal yellow, immature colon carcinoma transcript 1.Cell structure, motility, adhesion.
Dystrophin, glial fibrillary acidic protein, TNFa -induced protein 6, Wiskott-Aldrich syndrome protein interacting protein, structural maintenance of chromosomes 4-like 1, adaptor protein complex AP-2 a 2, d -like 1 homolog, dynactin 1, flightless 1 homolog, kinesin family 5B, chemokine ligand 1.Protein folding, degredation, proteolysis.
Peptidylprolyly isomerase B, carboxypeptidase D, ring finger protein 13, heat-shock protein 1 b , proteasome subunit b 6, DNAJ (Hsp40) homolog D1, cathepsin F,chaperonin 7 h ubiquitin conjugating enzyme 7 interacting protein 3.Synaptic transmission, neurotransmitter synthesis, release and receptors.
Tyrosine hydroxylase, synaptobrevin like 1, NMDA receptor-regulated gene 1, GluR1, cholecystokinin, GABAA receptor b 1, glutamate receptor ionotropic kainate 5 g 2, glutamate receptor NMDA z 1, synaptotagmin 5, preproenkephalin 1, potassium channel Q2.Transport activity.
Aquaporin 4, monocarboxylic acid transporter 1, SEC23A, diazepam-binding inhibitor, fatty acid-binding protein 3, ATP synthase H+ transporting F1 O, sodium bicarbonate cotransporter 7, ferritin light chain 1.Cell metabolism, enzymes.
S-adenosylmethionine decarboxylase 1, farnesyl diphosphate synthetase, carbonic anhydrase 14, phosphoserine aminotransferase 1, cytochrome C somatic, PC4 and SFRS1 interacting protein 2, NADH dehydrogenase Fe-S protein 4, lysophospholipase 1, annexin A3, aldo-keto reductase 7A5, cytochrome C-1, glutamate-cysteine ligase modifier, glycosylphosphatidylinositol specific phospholipase D1, GTP cyclohydrolase 1, prostaglandin D2 synthase, sparc/osteonectin cwcv and kazal-like domains proteoglycan 2.Others.
Carnitine deficiency-associated gene expressed in ventricle 3, endomucin, sorting nexin 13, lymphocyte antigen 6 complex locus A, semaphorin 4B, prominin 1, and 35 ESTs , complement component 1Q g , F-box only protein 21, flotillin 1, Golgi reassembly stacking protein 1, immediate early response 2, Ig 8, longevity assurance homolog, neighbor of A-kinase anchoring protein 95, neuronatin, prostate tumor overexpressed gene 1, seizure related gene 6, stromal membrane-associated protein 1, WW domain-binding protein 11, tumor protein D52-like 1, TBC1 domain family 1, signal sequence receptor a , and 19 ESTs.