My short name TLR Numerical Designation Species common name Species scientific name Scaffold # Length (aa) Notes Sequence ch 8p chicken Gallus gallus reassembled from raw sequence reads NA pseudogene GGGGGAAACGAATCTCGCCCTGTGGTGGATTCTATATTCCCACATCAAGGGGAAACAGTATTTTTCGTAATAGCATGAGAAAAAGATGTATAAATGATCACCCTCAGCTGATACGGAAACTCAAGTCACAAGCATCACTAACATAATCTGATGGGTAAAAAGAGCACACGTACTATTCAGATAATCAACACTAAACAATACCAAAGTATCTTGGATTTGGGTAAAAAAATATCATCTTCATAAATATAAATGAGTTTAAATTTCCTAAGGGTATAGCTTCTTTGAATTTTTCTTCAAATACTGTTGTGAAGCTTTCAATAACAGTGAATTAATATTTCACCTAGTTTGTAGTATTTACATCTCTTAACAAATTGGAACACACCAGTTATTTTGCATTTAGAGAGGTGCATAATCTTGAGGTAATAGACTTCATCTATAACAAATTTTATATTTTAGTGGTAGATTTGGCATATTTATTGAAAACATTCCTGAATTAAAGATTTCGCATTTAAACTTGAATGATATTTCTCTGTTATTAAATTTTAACTAGGAAGTTCTTCCCTTCAGAAATGAGGCTTCAGGGAAGGTATCTTTTTATTATATGACAAAATGGAAACAAATTATATAGGATTACATAGGTTAGAGCTCTTCTTCTAACAATCTTTTATATATCCCTCTGAGGGCATTTGAAAATCTGCCAAAGAGCTTAACTGAACTGTATCTCAATAACAACAAAGTACACATTCCCATCTGGGAAAAACTTAGCTACTTTAAATCCGTGAAGCTGCTTGAGTAAGAACTGATTAAAGGCAGATATGCAATTAAATCTACTATATAATTTCACACAGCTATTTCATATTCCGATTCTGAAACAGAACAAAACTGTTATGATTTCTACTGAGTTGACTAATGGATCACTGCATCCAGATTTGGGTTGTAAGTGGCTCCAAGGCTCAGGCAAACTAACATTCCCAGTGGAAATTAGAGAAGTTCTCTTAAATGAAAAGGGAACTATTTTCATCACACTTATTCATTTCAGAAAAGACAAAATTCCTATCTTGCAACTGCACAATGTTTCCTATTTATTTCCATGGAAACCACAACAGATATAAAGAGCACAGCAACACTGATAGAGCAAATTCTCAGCAAGAAAACACTCTTTTACAATGTAATAATGACCATGAGCTATGCATTTTCACCAGTGAAGTACAAGAACCTGCATGCCATGCTCATAACAACCTGCACCATTGGAAGTGACCCACCGTTGCTGTCTCCACTGCTGAGATGCACCACCCACCGCTTCACTGTGCTCACATCCACTGAGTAGTCTCCATAAAAGTTCAGCAAGTGTTGATGAATGTCACTGGGTGTCATTTTTTCCACCTGGAGGAATTCAGTGACACACCATTACTTCATCTGTACTTCCATGTGAGATGCCACTGTGTCAGACTGCCTCTCTACTGTCATTTGTCTCGCGGTAACAACATGTAATGGAATATTGGTGAGAAGGTTCAGCCTCTACTGCCATACCACCAGCATCCGCTTCTGATATCGTGGACCAACAGAATAGCACACTGGGCATTACTTTTGGAAAAGCCCTCATACCATCCACAAGAATCCACTCAACCAAACATATTGCACAGGACATCTGAGAAACAACATGACTGGCTAGAAAGTGCTGAGTTTCCATTTCACCTGAAGGAAAAGGGTCAAATAGGTCCTGATGTGCCCAGAAGGAAGGATCTGAGAGATGGGAAAAGCTGTGGCCAACAGATGGGTGCAGAGTGTATAAGTGGCAGAAATATAGTGTCTGTCCTATCAGGAATATAAGAAAGGGTTAGTGGAGGTGCTGTGAACATGGAACTGTGACAGCTGCCTGAGGGAGGGCAGAATTATTGAAGAATTTTTAACTGGGGACCCTCAATACTATAGATTGCTATTAAAAACTAATAAACAAACAGAAATATCATACATTTTCCTTTCATTGAAGTTTTGTGCTGCCATTTTCAGACCTATTGACCTTCTGTATGCAGTGTAACAACTGTAGTCATCTTACCTTGTTGCAGTGCTTGCATTAGAAGGAGATGGTTTATGTTTTGGAGGTGCTCTTTTCTCCCCACCAATTACAAAGGAATTCATGAAGGCCCTGGAGTGTATTCAGAGAAGGGCAACAAAGCTAAGGGAGGTCTGGAACACAGCCCTTATGAGAAGCAACTCAGGGAACTGGGATTGTTTAGTCTGGAGAAGAGGAGGCTCAGGGCAGACCTCATTGCTCTCTACAACAACCAGTAAAGAGATTGTGGTAAGGTGGGGGCTGGCCTCTTCTCCCAGGTAACAGAAATAGGATGAAAGGAAACAGCCTCAAGTTGTGCCAGAGGAGATTCAGGTTGGATATTAGGAAAAGTTTTCTTCTCCAAAAGAGTATTCAGGCAGTGGCACAGGCTGCCCAGGGAGGTGGTGGAGTCAACATCCCTGTAGGTATTCTAGAGCCACGTACATGTGGCACTGAGGGACTGTTAGTGGACATGGCGATGATGGGTTGACAGTTAGACTAGAATATTTGAGGTCTTTTCCAAAATTAATGATTCTGTAATTCTATGAAAATATCAAATCCGTGACATTTGTATTTTAACAAGTCAATCCCACATAAGCTGTGAACTACATGTCTCACTTGGGCAGCCAGGGCTAGCTGGTAAGCTTGCTTACAACCTGCAGCTGGCAAACATCTGTAATGTAAATATTGACCCTGCCTGTGGCAATGAAGATGATCATGTTGTGGATGTTGCAAACAAATATAGAGTGTATGTCATCAGTAATACTTGTGTAGATCAGACTTAATGCTTGTGAGCCAAACAGCTACTGAGGTTTGTTTGTTTGTTTGTTTGTTTGCAGAACATCTGATGTTTCCCATCAATGCTGAAGCTGTTACACAGGTGTCGAATTCATGCTGTCTGCATGCTCTTGACTGATTGCCCTGCACCACTTCACATGTGCAGCTAGGATTGATTGGCTAGTGATAATGCACATCCAGAAGGCCTTCATACCTACAGAATATCCTTGGTGTCAGTATATTTAAAACTGAGGAGGCAGACCAAAGAGAACAAGCCTAGCTGACTCACGGCCACACTTCTTTCCAGTTGTGGGGTCCCTCCCCCATTTATGGCCAGGTTCTGCTTTCCTCACACTGTGCTGAAACATTCCCACAAAAATCAGTTCTCCATTCATGAGATCAGCCTTTCTACAGCCAACTCCTCTGCACTCTGCAACACAGCTGGTGCTGCAAATAGCTGTCCTGTCAGACGCTGCCCTGTTGGCTACAAGCTTGGTACTGACATTGAGTTTGATGCAAAGCAGTTCTGCCTGCAGTATTGTTCTCTGATTAACAGATTTAAACTCTTTTAAATTCAGAATTGTCTCATTTATGCTGCAGACTAATTATGTGCTGCTATACTCATGTTTTCACTTTATCTTCCTCCTCCTTTCACCAACAATAAAAATTTGTAAAGCACCTGGTTCCTGTTTCATAGTTTTTGATTCCATCAAAAGTTTCAGACTTCCCTTTAATCCTTCTTTCACTTCTTGATTTTAAGATATCCGATTACATACTCTAAAAAGAAATTGTTCTTGTATTTATTCTGCAGGTAGCTTGATAGCGTTCCCATTTTAGTTAATATATTTGCTTTGGTGCTTGAGACTGCTTGAGGAGATTTTGATATTAACCTCCTGTCATTAGACATCTTTATATTCTGAAAGGGATTTATCAAAGATAGAGTTTATATACTTTGCAGTGATGTAGAAGTCAAACTCATGCACCCCCTTTCCAAGGACGCGAGGTTTACCGCAGGAACACGAGTGTCTTTCAGCAAACTTACCACATTTAGTAAGGTATCACAATTCTTGCAAGTAAGTGGCATGCACTCTTATTTTTATTCTAAGAAGTTGGAATATTTCAGTTTTGATTAATACAAATTTGTAAAGACCCACAGATCTTTTGAAAATTTCCACATAACCATTCTGTAAAGATTTAAATCTGTGTTTGCGTTGAACAGACACTCAAAACTAGAAAGATCAGTACTTACTTTCTCACACTGCTGCTAACATTTCTATCTTTTATTTGCAATGCCATAAAGAGACAATTCAGGTCACAGGATGGAGACAACAAAAGACAGAAAAGGAGTGTGCAGCATTGATTTAAACTGAGTCCCAATTAAGCCAGTGGTAATTTTTCCATGACTTCAAGGGCTTTTGAATTATGCCCTGAGGGGCAGATTTGAAAAGTAATGTAGGCACCAGCTTTTTTTGTAAATCCCACTTGGTACCTGTCCATATGTTCAGGCAGCTGAATAACAGTGAATTTCTGCGCTATCAGATATCCCATGTTTCAGAGGAAGTTATGTTTCTGCTGTTGCAGACTGAGTTACACCTTGCTGATACTCTTTATATAGTCTAGTCTTCAGATCTTTTTCCTCAGCACTCACTGTCAAGGTAATTTAGCTGCTTGCTTCTACTTTTATTGCTTCCAACATGTGCACTCAAATAGGACACATGCCCTCTAGCATGCCCCATCATCTAGTCTTTGGCCATATCTTGACTGCACAGTCGGAGAAAAGATTTGGACAAACAAAACATCTGCACACATCTGAGTTCCTACTCAGAGAAAGCCCCAAACTGCAGCCAGAAAGGGATGTGCAATGTCTTCCAACAAGTCCCCAGGCCAGGAGGCAGAAGGTATGTGATACGCTATGGAGTACACCTGGTACCGGGCTTAGGTAGGGGCAACTTGGGCTTGTTGAGACTATTGATGATGACATTTTGTTGGAAGGAGTGGGTGAAGACTATGCCACTTTGGTACCTGATTACATTCTTCTCTTCAAGAGACTACCCTTGGCTTATACTCTCCTGTAAGCTAGAGATGACTCACATTTGTCATGACATAGTCTCTTTCTGCAGTACTTGAGGTGGGAGCAGCTCAGCTGCTCAGTATGTCCGCTTTTTGAAGGCTTTTTCTGCTGACTGATAACTATGCTTGTTTTTGTGAGCAGTGACAGTGCTTAAGGGTTTTTTTGCATATTTAGAAGGGCTAAGCCAACAGCATTGTTGTTATTCTAGTACTGTGCTTTTTTATTTTACCTTTTTTTTTCTTTTTTTTATACTAAAATCAGTGTCTATGTTTGACAGACAAGTTTGATTAACCCATTTGCACAAGATCCCATCTTACCTTAACTGTTCAAGCAGAACCTTGGCACAAGACTTTGATGAGGTTCATGATTTTTGTTGGCATGTAAGAGACCTTCAAGATGTTCTGGTGTGAATTGCACTGGCAGCTGTCAAAAGCTTCCATAAGCCCAGATAAGTTTAAGTCTCTAAATACTTCTAGAAATATGTCTCTAATTGAACTAGGTTCTGTAACTTTTGGATTTAAAACCTTCTGTCAGTATTTCTGGATTTAAAATCTGCCCTGTTTATCATATGATGACCGCACTAGTTGGGTCATCTTTTCAACTTCCATCTTATAGCTCATGCCTGTGAAAGCTACAGTCATCGATAAATTGCAGATGCATGGATCACATGAAATTCACAGGCACTTCCAGCTTTAGCCTCTTACAGACCTTTCACAAATCAAATTATGAAAAACTACCTGTATAGGAAAAAAGGTGCTAGATAAAAATCTTTTACATTCCTTTTTACTTTCCCCTTGGCTAGAGCACTGCTACTGAGACCATCTTATTGTCATAGACCTTCCCCTCGCACTCAGGTCACACACTGAAGCACAAATCTGTACTCTAATTTCCCCAAACCTTTCTCCATATTTAAACCTATGTGATGACATCAGCAACGCAGGACATTTTCTGATAGTATGAAAATATTATTCTGCTCCTGCAGAAAGATAATTGCTAACACCCCTCTTGATGGAATGCCTATCTGTTGTAGATGATTGACTGTCTGCTTCAGTTCATAATCAGAAGAATGAATTTCCTACTGTCTTCTGAACTGAAAAGTTAAAGGAGTGAGCCTGACTACTCTACCAGCTCAAAACATGTTTTAGTATTCAGAATACCTTCCTTTTTCAATAGGATAAAAGATGTTGAAGATAAAAATTGAAATGAGTGAAAATCTTTTTTTTTTTTTGAAGTCTGTATAGGAGGGTAAACAACCCCAAAACTGCAGTTAGTGTTCAACTAATTACTGATATTTGTTACTCAGTGGAAAGGAGAACCAAAGAATCTATTCAGAAATAATTCAGAATATCCTGTAGTCTTCCACTTATGAGAGCTGTAGGCTGAAATATTTGTATGAAGAGGAGGGAACAATGCAACTACCCAGTCACCTCTGTTACCAACTGTAACCACTGAGCCTGGACAGAAATAAGGGGAACTGAATCTAAACCAATTAGCAAAAGCAATCACAATGCATTTTTGATGAAATATCATAGAATCATAGAATCTTCTGAGTTGGAAGGGACCCTTAAAAGGCCATCTTGTCCAACTCCCCTACAGTTAACAGGGAGACCTATAGATAAATGAGGTTGCTCAGGGTGCCATTCAGCCTGACCTTGAGTGTCTTCTGGGATAGCTTTCACTACATCTCTGGGCAACCTATTCCAGTGCCTCACCACACTTATTGTAAAAAAAAATGTCCTCATATCTAATCCAAATCTCCCCCTCTTTTAGTTTAAAACCATTTCCACTCATCCTATCACAACAGACTGTGCTAAAGAGTCCGTCCCCTTCTTTCTTACAGCCTCTCCTTAGATACTGAAAGGCCACTATCAGGTCTCCCTGGAGCCTTCTCTTCCGCATGCTGAACAGCCCCAGCTCTCTCAGCCTGTCCTCGTTCCTATGAGGACAGAACTCAGTACTTTTATTTTCTGGTATTTTCAAAATGATTAAATCTTCCTTGTTATGTTTTTAAAGACCTATCTGACCATCCCTGAAAAAGTCAGGTTTTTTGATCTTGGCATCAACTTTATGAAACAACTCAACTTCATTATCTTTCAAAGTAAAAAAGGTAATCTACAAGATGTCACCTTTAGTACAAAATAGGTCTAGCCTGTTAAAATTTGTTGAAAAAATGTCTATTTTACTATGTGAAATGATAAGTAACTGAGACATTTCATGCACTTTCTAGGACAAAACAAGGGACATTTTATGCTATCTATCTGCTCTCCGACCACAGCACATCTGACCTTGCAAAGCGCTGAGTTTCAGCTTAAAAAGCCTCACATTCATTAACTGGGATCAGTTTAAGCTCAGATCAGTTAATAAGCTTTGGGGAAATGGCCCAACTGAATTTGTCTGCAAATTGCGTTAGTCAGGCATTGAATGGAACTGAATTCAATCAGAGTGGCTTCAAATATTTAAATCTGTCTATCAAACAATATATTGGATTTTACGTGTGGTTTTGCATTACAAGAAATCATAAATCTAGAAGCATTAGACTTGAACCACAATAGGCATAAGTAACATCTCAGCTGGCACTTACTGAAAGCCTCCATTGCCTGAAGGTTTTTAGCTGGTGGTACATTCTCTACAGATAGAGACAAAGCAGCAATTCTCCTGAGGAATCAGCTTTCAAAGGAAATCACTTCAAAGTTTCATGGGAAAAGAGATACAGGGAAGACAGACAGTTTTAAAGAATCTCAGCAACATAACACATCTTGATATATCCCACATTAAACAGCTAACAATCCCCACAGAAACATACTTACTATTCCAGCTCCAAAAGGCAGCAAGCTGAAAGCCTTTAACTTTACACCCTCCACTGCATTTATTTTTGTGAAGATGAATGATCAGAGCTTTGGACTAAGCATAACCACTGATGTTTCCCCTGGAGATTCCTGGACAACTCTGTTGATAAGACTTAACAGAATTTCAGGGATTTTTGCAAACTCTTCTGTTGAAGAAGGCTATCCTTGGTACCTTGAACTGAGTTACAGCATAGTATGAGAGCCAATCAGCCTGCAAGGTTTGAAAAGGCATACAGCTAAGAGGTAAACTGACAAAGTAGTAACTTCATCAAAAGGAAGCAGGATGCTCACAGTTTTATACTGTGGGCAGCAACAAGAAATTGTGCAAGTCCATAGAATCATAGAATCACCAAGGTTGGAGAAGACCTGTAAGATCATCCAGTCCAACCTTCCAGCTAATATTTCCCCACTAAACCATGCCCCTTAGTACAACGTCTCTAGAGCACCTCCAGGGACAGTGACTCCACCACCTCCCTGGGCAGCCTGTTTCATTACCACTCTTTTGGAGAAGAAATTTTTCCTAATGTCCAACCTGAACCTCCCCTAGTGCAACTTGAGGTCATTTCCTCTAGTCCTATTGCTAGTTACATGGGAGAAGGAGCTAACCCTCACTTCATCACAGCCTTCTTTCAGGCAGTAGTAGAGAGTGATAAGGTCTCCCCTGAGTCTTCTCTTCTCCAGACTAAACAATTCCAGTTCCCTCATCCTCTCCCTGTAAGTCTTGTGCTCCAGGTACTTCACAGTTCACTTGCCATTCTCTGGACATGCTCCAGAGCCTCCGTGGCTTTCTTGTAGTGAGGGCTCAAAACTGCACACAGTACTTGAGGTGTGGCTTCACCAGTGCTGGGTTCAGAGGGATGATCACCTCCCTGCTTTTGCTACAAACACTATTTCTGATACAAGCCAGGATTGCATTAGCTTTCTTGGGCACACTGCTGGCTCATGTTCAACTGAACATGAACATGTTCAATTGAACCGACACCTAGAACATAGAACACAAAACCACAAAGACCATAACCCTGTAAGAGAACATCAGAGCATGTTGAGGAGTTTATGATCCATGTAACAACTGATTTGAGGATCTGACTGGGCATTGAGGGCTTTGCCATGCTGCACACATCCCTTGCCATATGATAAACACAGCCAGCCTGCAGGCAGCACCCACGTGGTGCCAGCAGTGATGTCAGCAGTATGTCCTTGACTTTATCTTTGTGACGTGGTATGTTTTCACATAAGAATCCTTTAGCACCACAGTAACAAATAAATAAACAAATAAACAAACAAATAGATCTGGTTTGCTTCTAAGACAATCCTATGAAAACTCTGAAGATGGCAGTTCTAACAGACCTTGCCATGTATAGGAAGCCTGCACAGAGTTTACATCTTGAAAAGAGGTCTAACGCAATATCATTTCAGGGCTCCCAGCATCAGAAGGGACCGAAGATGTTACAACTTGCTGTCTGGTTTTGTGGGATATCAGTAACACAATTATCTTTCTTGAGAGTGCTTGTAGTGCTTTTACTGGAATCAAAAGCACCAGCACTTTCAATACTAGACAGATGCTATGTATGCTGGTCTGGGAACCTGCAGGTGGTTTCCGCCTGTTATTAACTCCACTGTGATAGCAATCACAAAACATTTATTTTGCTGAGAACCCTGGGACACCTACTGCTCCTGTCTGACAAAGTGCCTGGCTCTGTGGCCATGGCCACAAAAGACTCACTCTTACAATGTGCACATTGTGTAGAACACCTGACAGATAGCAATGATCATCCAGAAAGCACTGGGTTTCAGTTATTTTTATTTTTATTTTATTTTATTTATTTTCTGGAGAAAAAAGAGGCAAGTATGTACTGATATGTCTAGAAATAAGGGGCTGGGAGCTGGGCATGACTGTGAGCAGCAGCTGCATGCAGTGGGGCCAGGCAGAAGAGAAACATTCACCCCCATTATGATTACATGGAAGGGTTCTCAAGGTGTAGTGGCCTGTAGTGGCCATTGTTCTGCCAGGTCTTTCCTGGCAGTCTAGAGGAGCAGGGCTTGTGGATAATACTCTGCAACATGGTGGGGTGTTTAGGAAGTGAGCAGTGTGTTTTATTCTCTGAAATGTGCTGTTTCGTTGCTATGACAAGCTTTGTTCCTGGGAAATCCTGGCTTTCACATTTGTAAAATTGCAGACAGATGCTACATAGGAGACACACAGGGAAAGGCATCATTGTAAATTTTAAAGGAATTTCTACTTGTAAGATTGTTTACTAATTCCATGTAGGACATTCATTTACTTACTGAGTGACTCTCTGAGTCTCTCTACCCTTTCTCCTACCATTTGTGCAAAGCAGATAGTAAGAATCACTTTGTAAGTCATTTTGTATCTATAAAGTGATTTGGGATGCCAGGATGTAAGGCACAGGGATCCTCATCTTGCTAGAGGGAGATGTGTCAGGATCTCCAAGATATCTCAGTCAATATTCAAGCTATTAAAGTTACTGATGAAATATTAGAAGCATAGAATCATAGAACTGTTAAGGTTGGAAAGGACCTCTAAGATCATCTAGTCCAATCAACAACCCATGCCCACCATGCCCACTAACCATATCCCTCAGTGGCATATCCACACATTCCTTGTTATTGATCATTTAAAGTGATTCTACCTTTCTCATGTGTAATGTGTAATCATTATGATTGTTTTCCACATTGGTCCCCTTGCTTACAATCCTGTCCAGCTCCTGGGATTTATGCATCTAATTTCCAGTCTGAGTATATGTTGGTGTGTGTACACCTGTGAAGCTGAATACAAAAGGGTCAGGACTGATCCCTGACCTCAGGCCAAGTAACATTGCTGGCTGGTTTCCACACAACTTAAAGCCAGTCTCTTGCTTTGAAGCTTTAGGGGTGTAGCTGGAGTAGTCCAAAACAGGGGATGAATTGAGCACCAAGGGGGGTATATGGCTGGGTATGCAGAGCTTCATTCACTCCCAGTGTGGATCCTTCTGGTGAGGATGAAATTCAGTAGGACTTCTTGTGCTTAGATGAGGTCTAAGAACATGGAATGGGTAATGGTAATGTGGAAATTCTCTACATTAGCCCAGTGGTCATAGCATTCTCACAAGACAATCAGCAACTGGTTTCAGGGCTCTTTGCCTGAAGAGATTGAAATGCGGTTTTACCTGATCAGGATGAGGGAGAGTTGCAAGAAAGGTATCTGAAGGGGGTTTATCTGGAGATAGCTGCAGCCTCTTTAGGCATGTAGATCTTATGCATGTGCATACTCTATGTATTCCTCCCGTGCCTTATCTGTGTAAAAATGAGAACTGATGGACTCTTTGGCAGTTGAACATAAAAGGAGGATTTGTGGAAAAAAACAAAATCAAAATCCCCCAAAGTTTAGAGCTAGTCTCCTTCCTTAACTTCACTGAAAGTGCAGTCAACTTGAACTAATATGATACATTTTGCACAGCAAGGTGGGCTTATCATACAGTGACATGTTGAGGTGTGGAACCAAGCTGTCTCCTCATGAAAGATGGATCAAGACAGAACATCATCCTCTGAACAGTTTTTTTGAAGATAAGATAGCAGAAGTCATGTCAGTGGCAAAAACAATGTAAAAATAAATGCTTTATTTATTTTCTGATTAGAGAGTGAGACCGTGCAACTTAGTGAATTGCAGTTAATCATTTTAGAGTGATTATTTCTCTTAGTCTTTGGTTCTCTGTCCTCTCTCTCTAAGTGAAATTTATTGCAAATCCTACCACCTGTGAATTTCATTAAATTGAAGGTGGTGAGTTGTGGCTTGTACACACTTGAGTATTTCCAATTTATGTCTCTGCCCAAGTATCCAAAAATTTGCCAGAAGATGTTGCAATAAACAGTTCCTCTGTCATTCCTGGATGTAGTATGCATCACCTGAAGTGAGTGCATGGTGATGCAACTGAGCTGAAACTCCCAAACAACTGAAATAAGAAGGTTTTAGAAAAATTTTTCAGGGCCTGAATAAGCTAATTAAAAAAAAACAAAAAAATTAAACAGGAATCACTATCCAAAGGCAATGGAAATGTCTCAAGATTTTTGCAAGAAACGGGTAAAAATGAATATGCAACATTTGCTAGCTGAGCACATGTTAAAGACTTGCTGTCTGATGAAAACCATTTATGTAAACACCTTTAACCACTCTGAGCTTTAGAAATAAATGATTGCATAATTTCCATCAGCAATACTTCTTTCAGCACTTGCATGGTGGAAGAACTCTACTTGAACGCAAATTATCTTTACAATAACCCCTGTAGAAAAAGAATTCTGCACTGAACCCTTTTTCTTCCACACTTTGCAACCACATCTCCACCTCCACTCTCTGAGGCCAAGATGATTTAAGGCCTAAGGACATTGGAAGCTGTCCAAGGTACTTCCTGGGTGCTCGCACACAGCTATGCCCTCCACTAACCAGTACTGGTGACATTGGTGTCGTTTAAGCCTTCCTCCTATTATAATTTTCAGCTGGCTGTATTGCAAAAACAATTGTTCCTCTTGAATACAGATGCTCAAAAAAGGATACAGCCTCAGGTGAGTTTTTATTCCACCACATTTTGTTGCTTCTTGATTCATATTTTAATTACGGGGAAAAAAGAACAGCCCCAGATATATAAGCATTTCTAACAAGTCCCATAATCTGCTTCTTTTCAGCAGCTATATTAAAGAGATTTGATGTTCAAGGACTTCATTATGAACAGCAAAGCCCGTTAGAAATCTTAAAATCTTCTTAGCTGCAGTTTTGGAGTTCTGTTTATCAAGCAAATTGATCTCAGTCTTTCACTGAGCAAAGTAGACTGAGCTGCCTGGAAGCAGAATATCACCTTCATCACAGGGTAACAACAACAGTACTATTAGTAGGAAATCAGTCAAAGACAGATATAGACCTGGAGGAAATAATATGCCCTTGCCAGAAGATAAGCCCAGGAATTGATACATCTTTGCTCAAAGCACAGTGCAGAAGGTTTGATAAATCTTTCAAAGTTCAAACAGTGATTTTCTTCACTGACAAAAAGCAATTTGAAGGTGTTCAGTGGGTGTTTTGCTTGAATTTGTCTTTTGATATCATTAGCCGTGGTCTGAATAGTATCTATTCTGTCTTCCAAAATTATCTGAAGTATTTAGGTCTGACTAGTAATAAATTGGACTTAGTTTCTCATTATGCTTTTTTTGAACCACTCTCTTTAGAGGTGATAGATTTCAGTGAAAATAAGCACTACTTCACCATGGCAGGAATAAAACATAAGCTGACTTTTAATACATTTTTTTTCTGTGACCTTGAAAACAATGAAACAGAGCTTTAGGGGGCCTACCTCATGTGTACACACGTGAATAAAGAAATCATGAGAGAAGAAAATAATGGTAAAAGTATTCATACTTGTGGGAAATCAAACACACATAGAATCATAGAATCATAGAATCACTAAGGTTGGAAAAGATCTCTATGATCATCTAGTCCAACCACCAGCCCATTATCATCTTGGCCACTAACCATGTCCCTCAGTGTCACTTCTACATATTTCTTGAACACCTTCATGGACAGTTACTTCACCATCTCCTTGGACAGCCTGTGCCAATGCCTCACCGCTCTTTTGGAGAAGAAATTTTCCTAATATACAACCGGATTTGAGGGATTTCTCTGCATACCTCCTGCACACATTGTTAACAACCCATGTCCAAATGTGATTGCAGGATTAAATAAAATTAATTTTGTTGGTATGGAAAGCTGAACTCCTCTGAACTCCTCTGAGCTGTTCCATAAGCCCTCAAATATGCCAACAGTCACACGACCCCACCTGAGTGTTCTCATCCTTATGTGACCACCTCCAGCCAAGCTGATCCCATCCCCAGACCCTCTCCCACCCCTTCTGAAGTAATACAGCTGCTCCCCCAGGGTTTACACGTTTGGTGGATGTCTTCCCTGTATGCCTAGTGCCTAACGGGGGGGGAAAAACAAACAAGAAAGAAATTAAAAAGTTCCCCTGTTTTGACCCTGCCCCTCCCCTGTGAACATCCCTTCAAAAGCCCCAAAAAAAAAAAATAGGGGAGGGGGAAATTTATTTTCACCCCCACCCCTCGGGGAAACGGCCTTCCACAACAATCCTATTGAAAAAAATCCCCCCACCCCTCTTT ch 1-like chicken Gallus gallus "Contig595, start at 10298" 652 appears to be partial (LRRCT 384-437; TIR 495-639); N -terminus may be in a gap MTKNMRYLRNCFIYNCLFVFTFWDNIGLAKKNELFASVPNNFLEDGLDKKNMSFPHSYANNQHYKADYGWVVIENTTESLSLSEIADDNVRKLITLLSKFRKGSRLRNLTLTNMSVDWKDIIKVLQVVWHSSIEYFNINNLTQLGNVVSTRFDYSKTSMKAFAVNKVLITDLYFSQDDIYNIFANMNIAALTIAESELIHMLCPSSDSPLRYINFSKNDLTDLLFQNCDKLIQLETFILHRNKFESLSKVSFMTSRMKSLRYLDMSSNLLRNSRAEGRCQWADSLAELDLSSNQLTEAVFECLPANINKVDLQNNQIASVPKGITELHSLQELNLASNRLADLPGCRAFTGLEILNIERNLILTPSADFFETCPSVKELQAGQNPFKCSCELQDFLRLERQSGGKLSGWPEAYVCKYPEDLSGTQLKDFHLTELACNTTLLLVTALLLTLVLVAVVAFPCIYLDVPWYVRMLWQWTQTKRRAWHDCPEERETALQFHAFISYSERDSLWVKNELIPNLEKGEGCIQLCQHERNFIPGKSIVENIINCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHKLFSENSNSLILILLEPIPPYVIPARYHKLKALMAKRTYLEWPKERSKHALFWANLRAAISINLSVADEQNRTEV. ch 1L1 chicken Gallus gallus "Contig595, range 22719-25175" 818 MGSLTSIYVFACVFLSILWNNIQPTVENKITANYSGHLLTEVPKNIPVHTHILDLSHNSISEITNFRFTSLSDLQVLNLSHNLITELDFSAFMFNQDLEYLDLSHNNIWTAYCQLLARLRHLDLSFNKFTVLPICQEFGIMFHLEYLGLSAMMIRRSDFRYVAHLQLDTVFLTLEDFSLYEPLSLTALNTRSLHIVFATNQNFNFSLLYDGMSTSEKLKIVNLRYTLSHKDFPSPSLELQKKIKTTDLTLDTVDLEWTVILQIFLLVWDSSVEHLTVRNLIFRGPVVELTEYKHVPLLRSLEQLLSLGSSMKALTLERVRNKLYYFNQEILYRQFSEMNIDSLTIHDACMPHMLCPKKRSSFQYINFSRNALTDELFQNCDTLANLKILILHRNKFESLSKVSFMTSRMKSLRYLDMSSNLLRNSRAEGRCQWADSLAELDLSSNQLTEAVFECLPANINKVDLQNNQIANVPKGITELHSLQELNLASNRLADLPGCRAFTGLEILNIERNLILTPSADFFETCPSVKELQAGQNPFKCSCELQDFLRLERQSGGKLSGWPEAYVCKYPEDLSGTQLEDFHLTELACNTTLLLVTALLLTLVLVAVVAFPCIYLDVPWYVRMLWQWTQTKRRAWHDCPEERETALQFHAFISYSERDSLWVKNELIPNLEKGEGCIQLCQHERNFIPGKSIVENIINCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHRLFSENSNSLILILLEPIPSYVIPARYHKLKALMAKRTYLEWPKERSKHALFWANLRAVVNIKLPTSFETDEEQSDVTSTSSITQCLIK ch 1-like chicken Gallus gallus "Contig13310, entire 1357bp" 451 "partial from a very short contig; both N and C-termini are off ends; based on syntenic considerations, this contig is probably allelic to Contig595 (range 10625-11968) as aligns at DNA level 98.4%" LTNMSVDWKDIIKVLQVVWHSSIEYFNINNLTQLGNVVSTCFDYSKTSMKAFAVNKVLITDLYFSQDDVYNIFANMNIAALTIAESELIHMLCPSSDSPLRYINFSKNDLTDLLFQNCDKLIQLETFILHRNKFESLSKVSFMTSRMKSLRYLDMSSNLLRNSRAEGRCQWADSLAELDLSSNQLTEAVFECLPANINKVDLQNNQIASVPKGITELHSLQELNLASNRLADLPGCRAFTGLEILNIERNLILTPSADFFETCPSVKELQAGQNPFKCSCELQDFLRLERQSGGKLSSWPEAYVCKYPEDLSGTQLKDFHLTELACNTTLLLVTALLLTLVLVAVVAFLCIYLDVPWYVRMLWQWTQTKRRAWHDCPEERETALQFHAFISYSERDSLWVKNELIPNLEKGEGCIQLCQHERNFIPGKSIVENIIYCIEKTTSSSLCCHPT ch 1-like chicken Gallus gallus "Contig539, is an overlapping (reverse orientation) allele of contig 595 (bp 1 of contig 595 is about bp 17126 of Contig539. Contig 539 has the complete LOC92689 but Contig595 has only part of it." 525 partial; gaps in middle of sequence MRGAERSAELPARSSAAAIRHPSDPRAMRSAALPPDSRRRFALRGTRPRCHLPQRKAGATAAPSNPQLPPFLPSFFSLLKPSGLEPPASSPQPVSKAAARKTQTAALLTAPRSVPAHPRLRPRPATSATAGGGGSAGRARRDGRAGPRRAEGGFCSRSPSVPPRRPSVAEWPPRVVGCRPGALRRPAAAAATLRGPTGRVRQRRSDKACKPVAAELNNGGFASSGPPDTPAVAVTGKAAEPLGGAPANFQQCPSRFFLFFPASYKGKACPFAAISSSTVHCSIASAARLPLLKKVTRSCPGGVTTHPMSRXXXXXXXXXLVTLVLVAVVAFLCIYLDVPWYVRMLWGWTQTKRRAWHDCPEERETALQFHAFISYSERDSLWVKNELIPNLEKGEGCIQLCQHERNFIPGKSIVENIINCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHKLFSENSNSLILILLEPIPPYVIPARYHKLKALMAKRTYLEWPKERSKHALFWANLRAAISINLSVADEQNRTEV. ch 2 chicken Gallus gallus MFNQSKQKPTMKLMWQAWLIYTALAAHLPEEQALRQACLSCDATQSCNCSFMGLDFIPPGLTGKITVLNLAHNRIKLIRTHDLQKAVNLRTLLLQSNQISSIDEDSFGSQGKLELLDLSNNSLAHLSPVWFGPLFSLQHLRIQGNSYSDLGESSPFSSLRNLSSLHLGNPQFSIIRQGNFEGIVFLNTLRIDGDNLSQYEPGSLKSIRKINHMIISIRRIDVFSAVIRDLLHSAIWLEVREIKLDIENEKLVQNSTLPLTIQKLTFTGASFTDKYISQIAVLLKEIRSLRELEAIDCVLEGKGAWDMTEIARSKQSSIETLSITNMTILDFYLFFDLEGIETQVGKLKRLSIASSKVFMVPCRLARYFSSLLYLDFHDNLLVNNRLGETICEDAWPSLQTLNLSKNSLKSLKQAARYISNLHKLINLDISENNFGEIPDMCEWPENLKYLNLSSTQIPKLTTCIPSTLEVLDVSANNLQDFGLQLPFLKELYLTKNHLKTLPEATDIPNLVAMSISRNKLNSFSKEEFESFKQMELLDASANNFICSCEFLSFIHHEAGIAQVLVGWPESYICDSPLTVRGAQVGSVQLSLMECHRSLLVSLICTLVFLFILILVVVGYKYHAVWYMRMTWAWLQAKRKPKRAPTKDICYDAFVSYSENDSNWVENIMVQQLEQACPPFRLCLHKRDFVPGKWIVDNIIDSIEKSHKTLFVLSEHFVQSEWCKYELDFSHFRLFDENNDVAILILLEPIQSQAIPKRFCKLRKIMNTKTYLEWPPDEEQQQMFWENLKAALKS ch 4 chicken Gallus gallus LHKLPFGLHSSVLSAFSTLQLLPEQDLPGSFGRLNDAPYEATYKLLQLNASSKRYAGFGYPGNHDTTTPIHYYNTGLSRKNELFQHNLTAERNWLLKMIDHFSQVFIERQLLLHSKRYKMQNRRQEVFQALQLLLVLSLLAGCIPSPCLEHLGLAAFHGLTSLKKLVLVETSISSLSDLPIGHLNTLQELNLGHNNIASLKLPKYFANLTSLRHLSFSSNNITYISKGDLDALRETNRLNLTLVLSLNNIKYIQSGSFAKIHLGELILRSSFENLNAMHSSLQGLAGLQVNRLIVGEFTNILKITAFQNGLLSGLCQVQMQEFVLMCFREFDNDTDTLFDCIGNVTTIRLVDLNLETLSEVPMFSQVKHLEWKKCKFQELPAEKLSLFKELRVLRITKSKDLNGFEQKFGSLTHLEVVDLSENRLSFLTCCSPKFPRSPNLKHLNLSFNSDISLTGEFANLRNLLYLDLQHTKLIHHGTYPVFLLLQKLIYLDISYTKTHVMSHLIFHGLNSLQVLKMAGNSFENNTLTNNFENVRRLRILDISSCKLVWVDQSTFNALSELKELIISNNKLLTFDPVTYKPLQALTALDFSNNQMSFLSDSALEILPDSLVLLDISHNLFECSCTHLNFLKWVKEKQDLLRNKHSMICHTPAYMKNMSLSNFDMSSCHPNPTTVACSVTVLLAAGVFLFLIYKYYFQLYYSLVLLSGCKHSAERGDIYDAFVIHSSKDQEWVMKELVEPLEEGKPPFQLCLYFRDFLPGVPIVTNIIQEGFLSSRNVIAVISADFLESKWCSFEFDIARSWQLVEGKAGIIMIILGEVDKTLLRQRLGLSRYLRRNTYLEWKNKEISRHIFWRQLTSVLLEGKKWNHEEIKLM ch 21 chicken Gallus gallus MCPSHCCPLWLLLLVTVTLMPMVHPYGFRNCIEDVKAPLYFRCIQRFLQSPALAVSDLPPHAIALNLSYNKMRCLQPSAFAHLTQLHTLDLTYNLLETLSPGAFNGLGVLVVLDLSHNKLTTLAEGVFNSLGNLSSLQVQHNPLSTVSPSALLPLVNLRRLSLRGGRLNGLGAVAAAVQGLAQLELLDLCENNLTTLGPGPPLPASLLTLQLCNNSLRELAGGSPDMLWHVKILDLSYNSISQAEVFTQLHLRNISLLHLIGNPLDVFHLLDISDIQPRSLDFSGLVLGAQGLDKVCLRLQGPQALRRLQLQRNGLKVLHCNALQLCPVLRELDLSWNRLQHVGCAGRLLGKKQREKLEVLTVEHNLLKKLPSCLGAQVLPRLYNISFRFNRILTVGPQAFAYAPALQVLWLNINSLVWLDRQALWRLHNLTELRLDNNLLTDLYHNSFIDLHRLRTLNLRNNRVSVLFSGVFQGLAELQTLDLGGNNLRHLTAQSLQGLPKLRRLYLDRNRLLEVSSTVFAPVQATLGVLDLRANNLQYISQWLRKPPPFRNLSSLYDLKLQAQQPYGLKMLPHYFFQGLVRLQQLSLSQNMLRSIPPDVFEDLGQLRSLALADSSNGLHDLPDGIFRNLGNLRFLDLENAGLHSLTLEVFGNLSRLQVLHLARNELKTFNDSVASRLSSLRYLDLRKCPLSCTCDNMWLQGWLNNSRVQVVYPYNYTCGSQHNAYIHSFDTHVCFLDLGLYLFAGTAPAVLLLLVVPVVYHRAYWRLKYHWYLLRCWVNQRWRREEKCYLYDSFVSYNSADESWVLQKLVPELEHGAFRLCLHHRDFQPGRSIIDNIVDAVYNSRKTVCVVSRSYLRSEWCSLEVQLASYRLLDERRDILVLVLLEDVGDAELSAYHRMRRVLLRRTYLRWPLDPAAQPLFWARLKRALRWVEGGEEEEEEGAGGETLKKWSVALGPQNCSWDAT ch 3 chicken Gallus gallus MTLSSAVEESLATKRKESKGLIFLKINRGYKLGGDEPSKLDNVQKADMVITSLKASVQDNYEVKNTWVSARAVTESLHSAPRRAPLSLSLLLPSPRRGLDISHNQLKKLDPENLTEYSNLIYLNAGYNIISKLKPGLCKNLPLLQILKLEHNQLHELPDGVFASCSNLTELNLGYNIIEVKNDPFKTLENLNILDLSHNHLKSANLGLQQQLKNLRELVLYSNQITELNKEDLKFLSNTSLNSLDLSSNPLKEFHTGCLHAIGNLFGLILNNVELGENRTKKLCTELSDTAIQNLSLSHVKLSHINRLTLQGLQGTNLTVLNLSKNSLSVIEDDSFQWLSKLEYLNLEDNNIINVSSHLFYGLSSITHLNLINSLTGKIEDFSFQWLHHLEYLIMDNNNFPRITTNMFTGLKNLKYLSLYNCNTNLQRITNKTFVSLANSRLQVLNLTKTRISTVESEAFSSLGQLKILDLGLNEINQELTGHEFEGLNNIEYIYLSYNKNVTLRSESFIFVPSLRKLMLRKVGCNNLAISPSPFHPLRNLTVLDISNNNIANIREDLFNGLHELDILNLQHNNLARLWKCANPGGPVLFLKDVPNLHILNLKSNGFDEIPVHVFKGLHQLKDLDLGSNNLNLLPATLFDDQTSLNTLNLQKNLITSVEENVFGPAFKSLRTLEMDFNPFDCTCESIAWFASWLNDTQAYIPGLQSQYICNTPPKYHGTLVLHFDTSACKDSAPFKLLFLITTTAVMQFMFIVLLIHFEGWRIAFYWNISINRILGFKELDRLPGVFDYDAYVIHARKDTNWVLTNFTTLEENEQFQVKFCLEERDFEAGISEFEAIINCIRRSRKIIFIVTEHLLQDPWCRKFKVHHALQQAIEQSRDSIILIFLHNIQDYKLNHALCLRRGMFRSCCILNWPVQKERINAFHQQLMMALKSNSKVR ch 15 chicken Gallus gallus reassembled from raw sequence reads MRILIGSLYFYFISFLFSKVNGFLTQRTSPVSSFPFYNYSYLNLSSVSQAQAPKTARALNFSYNAIEKITKRDFEGFHVLEVLDLSHNHIKDIEPGAFENLLSLVSVDLSFNDKNLLVSGLAPHLKLIPTSGASGPSQIYMYFQKSAEAALEPSAPAELLPHLEDPPNPGNVNPRFRQRRTEENKTSPPAATLRPDLCGAPINGLLDLSRTKLSNEELTAKLDADLCQAQLGTVLEFNISHSDLEMDLLSLFILFLPMKDIQSVDASYNRITINNIDVEAICHFPFSNFSFLNISNNPINSLETVCLPESITVIDLSFTNISTIPANFAKKLSKLERMYVQGNQLIYTVRPENPSATPRPPPGTVQISAISLVRNQAGTPIESLPESVKHLKVSNCSIVELPEWFANRMQELLFLDLSSNRISMLPDLPISLQQLDISNSDIKIIPPRFKSLSNLTVFNIQNNKLTEMHPEYFPSTLTTCDISKNKLKVLSLTKALENLESLNVSGNLITRLEPACQLPSLTNLDSSHNLISELPDHLGQSLLMLKHFNLSGNKISFLQRGSLPASLEELDISDNAITTIVQDTFGQLTSLSVLTVQGKHFFCNCDLYWFVNIYIRNPHLQINGKDDLRCSFPPDRRGSLVKSSNLTLLHCSLGIQMAITACMAILVVLVLTGLCWRFDGLWYVRMGWYWCMAKRRQYKKRPENKPFDAFISYSEHDADWTKEHLLKKLETDGFKICYHERDFKPGHPVLGNIFYCIENSHKVLFVLSPSFVNSCWCQYELYFAEHRVLDENQDSLIMVVLEDLPPDSVPQKFSKLRKLLKRKTYLKWSPEEHKQKIFWHQLAAVLKTTNEPLVRAENGPNEDVIEME ch 7 chicken Gallus gallus MTNLSEVAAHRKMVHHARTSNALLFVLLFLFPMLLSGRWFPKTLPCDVEAFESTVRVDCSDRRLKEVPRGIPGNATNLTLTINHIPRISPASFTQLENLVEIDFRCNCVPPRLGPKDNVCVTPPSIENGSFAALTRLKSLYLDANQLSKIPRGLPATLRLLSLEANNIFSIKKNTFSELRNIELLYLGQNCYYRNPCNVSFEIEETAFLNLKNLTVLSLKSNNLTFIPPNLSSTLKELYIYNNRIQEVQEHDLSNLYNLEILDLSGNCPRCYNAPYPCTPCPNISIKIHSKAFYSLKKLRILRLHSNSLQSIPSSWFKNIKNLKNLDLSQNFLIKEIGDAEFLKLIPSLVELDLSFNFELQMYSPFLNLSKTFSCLSNLETLRIKGYVFKELREENLDPLLNLRNLTVLDLGTNFIKIADLRVFKKFRSLKIIDLSMNKISPSSGEGNFYGFCSDHRITVEQYSRHVLQEMHYFRYDEYGRSCKSKDKEADSYQPLVNGDCMSYGETLDLSRNNIFFVNSIDFQDLSFLKCLNLSGNAISQTLNGSEFYYLSGLKYLDFSNNRIDLLYSTAFKELKFLEILDLSNNKHYFLAEGVSHVLSFMKNLAYLKKLMMNENEISTSISTGMESQSLQTLEFRGNRLDIFWSDGKKEYLSFFKNLTNLEQLDISSNMLNFLPPDVFEAMPPELKILNLTSNRLHTFNWGKLHLLTKLITLDLSNNLLTTVPRKLSNCTSTLQELILRNNRITRITKYFLRGAIQLTYLDLSSNKIQIIKKSSFPENIINNLRMLLLHNNPFKCNCDAVWFVGWINQTQVAIPLLATDVTCAGPGAHKGRSLVFLDLNTCELDTSYFIMYALSTSAVLCLMMFAVMSHLYFWDVWYSYHYCTAKLKGYRRIPLPDACYDAFIAYDNTDLAVNEWVMTELVEKLEDQKARQFNLCLEERDWLPGQPVFDNLSQSIQLSKKTIFVLTNKYIKSGTFKTTFYMAHQRLLDEKIDVIILIFLEKVLQKSRYVQLRKRLCRSSVLEWPTNPRSQPYFWQRLKNAIAMNNTLSYNKLLQETV Genbank My short name TLR Digit Species common name Species scientific name Accession # Length (AA) Notes FASTA chTLR2 2 chicken Gallus gallus NP_989609 793 GeneID: 374141 ch_not_a_tlr NOT A TLR chicken Gallus gallus XP_425176 935 blastps to COG4886 and KIP1 (LRR and kinesin-ike protein) chTLR15 15 chicken Gallus gallus XP_419294 868 "We initially hypothesized that the chicken sequence XP_419294 might be based on an imperfect gene model, causing incorrect phylogenetic positioning. However, reassmebly of the genomic sequence provides a high level of confidence in the local assembly." chTLR3 3 chicken Gallus gallus XP_420675 991 gene model may have some problems MGCSIPCWNSLSFRLVFVCLLCASVGKQCQIRNTMADCSHLKLTQIPSDLPKNITGldishnqlkkldpenlteysnliylnagyniisklkpglcknlpllqilklehnqlhelpdgvfascsnltelnlgyniievkndpfktlenlnildlshnhlksanlglqqqlknlrelvlysnqitelnkedlkflsntslnsldlssnplkefhtgclhaignlfglilnnvelgenrtkklctelsdtaiqnlslshvklshinrltlqglqgtnltvlnlsknslsvieddsfqwlskleylnlednniinvsshlfyglssithlnlinsltgkiedfsfqwlhhleylimdnnnfprittnmftglknlkylslyncntnlqritnktfvslansrlqvlnltktristveseafsslgqlkildlglneinqeltghefeglnnieyiylsynknvtlrsesfifvpslrklmlrkvgcnnlaispspfhplrnltvldisnnnianiredlfnglheldilnlqhnnlarlwkcanpggpvlflkdvpnlhilnlksngfdeipvhvfkglhqlkdldlgsnnlnllpatlfddqtslntlnlqknlitsveenvfgpafkslrtlemdfnpfdctcesiawfaswlndtqayipglqsqyicntppkyhgtlvlhfdtsackdsapfkllflitttavmqfmfivllihfegwriafywnisinrilgfkeldrlpgvfdydayviharkdtnwvltnfttleeneqfqvkfcleerdfeagisefeaiincirrsrkiifivtehllqdpwcrkfkvhhalqqaieqsrdsiiliflhniqdyklnhalclrrgmfrsccilnwpvqkerinafhqqlmmalksnskvr chTLR4 4 chicken Gallus gallus XP_415518 1195 gene model may have some problems >chTLR4 LHKLPFGLHSSVLSAFSTLQLLPEQDLPGSFGRLNDAPYEATYKLLQLNASSKRYAGFGYPGNHDTTTPIHYYNTGLSRKNELFQHNLTAERNWLLKMIDHFSQVFIERQLLLHSKRYKMQNRRQEVFQALQLLLVLSLLAGCIPSPCLEHLGLAAFHGLTSLKKLVLVETSISSLSDLPIGHLNTLQELNLGHNNIASLKLPKYFANLTSLRHLSFSSNNITYISKGDLDALRETNRLNLTLVLSLNNIKYIQSGSFAKIHLGELILRSSFENLNAMHSSLQGLAGLQVNRLIVGEFTNILKITAFQNGLLSGLCQVQMQEFVLMCFREFDNDTDTLFDCIGNVTTIRLVDLNLETLSEVPMFSQVKHLEWKKCKFQELPAEKLSLFKELRVLRITKSKDLNGFEQKFGSLTHLEVVDLSENRLSFLTCCSPKFPRSPNLKHLNLSFNSDISLTGEFANLRNLLYLDLQHTKLIHHGTYPVFLLLQKLIYLDISYTKTHVMSHLIFHGLNSLQVLKMAGNSFENNTLTNNFENVRRLRILDISSCKLVWVDQSTFNALSELKELIISNNKLLTFDPVTYKPLQALTALDFSNNQMSFLSDSALEILPDSLVLLDISHNLFECSCTHLNFLKWVKEKQDLLRNKHSMICHTPAYMKNMSLSNFDMSSCHPNPTTVACSVTVLLAAGVFLFLIYKYYFQLYYSLVLLSGCKHSAERGDIYDAFVIHSSKDQEWVMKELVEPLEEGKPPFQLCLYFRDFLPGVPIVTNIIQEGFLSSRNVIAVISADFLESKWCSFEFDIARSWQLVEGKAGIIMIILGEVDKTLLRQRLGLSRYLRRNTYLEWKNKEISRHIFWRQLTSVLLEGKKWNHEEIKLM chTLR1 1L1 chicken Gallus gallus NP_001007489 818 gene model may have some problems >chTLR6 MGSLTSIYVFACVFLSILWNNIQPTVENKITANYSGHLLTEVPKNIPVHTHILDLSHNSISEITNFRFTSLSDLQVLNLSHNLITELDFSAFMFNQDLEYLDLSHNNIWTAYCQLLARLRHLDLSFNKFTVLPICQEFGIMFHLEYLGLSAMMIRRSDFRYVAHLQLDTVFLTLEDFSLYEPLSLTALNTRSLHIVFATNQNFNFSLLYDGMSTSEKLKIVNLRYTLSHKDFPSPSLELQKKIKTTDLTLDTVDLEWTVILQIFLLVWDSSVEHLTVRNLIFRGPVVELTEYKHVPLLRSLGSSMKALTLERVRNKLYYFNQEILYRQFSEMNIDSLTIHDACMPHMLCPKKRSSFQYINFSRNALTDELFQNCDTLANLKILILHRNKFESLSKVSFMTSRMKSLRYLDMSSNLLRNSRAEGRCQWADSLAELDLSSNQLTEAVFECLPANINKVDLQNNQIANVPKGITELHSLQELNLASNRLADLPGCRAFTGLEILNIERNLILTPSADFFETCPSVKELQAGQNPFKCSCELQDFLRLERQSGGKLSGWPEAYVCKYPEDLSGTQLEDFHLTELACNTTLLLVTALLLTLVLVAVVAFPCIYLDVPWYVRMLWQWTQTKRRAWHDCPEERETALQFHAFISYSERDSLWVKNELIPNLEKGEGCIQLCQHERNFIPGKSIVENIINCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHRLFSENSNSLILILLEPIPSYVIPARYHKLKALMAKRTYLEWPKERSKHALFWANLRAVVNIKLPTSFETDEEQSDVTSTSSITQCLIK chTLR1_2 1 chicken Gallus gallus XP_428678 311 partial chTLR1_3 1 chicken Gallus gallus XP_428184 429 partial chTLR1_4 1 chicken Gallus gallus CAG32465 818 BLATS to same place as TLR1 NP_001007489 so allelic or alternative splice form chTLR7 7 chicken Gallus gallus XP_416836 1059 chTLR7_2 7 chicken Gallus gallus CAG32163 1059 nearly identical to XP_416836 (1056/1059) 99% chTLR21 21 chicken Gallus gallus XP_413989 1331 gene prdiction extens further N and C than expected >chTLR21 MCPSHCCPLWLLLLVTVTLMPMVHPYGFRNCIEDVKAPLYFRCIQRFLQSPALAVSDLPPHAIALNLSYNKMRCLQPSAFAHLTQLHTLDLTYNLLETLSPGAFNGLGVLVVLDLSHNKLTTLAEGVFNSLGNLSSLQVQHNPLSTVSPSALLPLVNLRRLSLRGGRLNGLGAVAAAVQGLAQLELLDLCENNLTTLGPGPPLPASLLTLQLCNNSLRELAGGSPDMLWHVKILDLSYNSISQAEVFTQLHLRNISLLHLIGNPLDVFHLLDISDIQPRSLDFSGLVLGAQGLDKVCLRLQGPQALRRLQLQRNGLKVLHCNALQLCPVLRELDLSWNRLQHVGCAGRLLGKKQREKLEVLTVEHNLLKKLPSCLGAQVLPRLYNISFRFNRILTVGPQAFAYAPALQVLWLNINSLVWLDRQALWRLHNLTELRLDNNLLTDLYHNSFIDLHRLRTLNLRNNRVSVLFSGVFQGLAELQTLDLGGNNLRHLTAQSLQGLPKLRRLYLDRNRLLEVSSTVFAPVQATLGVLDLRANNLQYISQWLRKPPPFRNLSSLYDLKLQAQQPYGLKMLPHYFFQGLVRLQQLSLSQNMLRSIPPDVFEDLGQLRSLALADSSNGLHDLPDGIFRNLGNLRFLDLENAGLHSLTLEVFGNLSRLQVLHLARNELKTFNDSVASRLSSLRYLDLRKCPLSCTCDNMWLQGWLNNSRVQVVYPYNYTCGSQHNAYIHSFDTHVCFLDLGLYLFAGTAPAVLLLLVVPVVYHRAYWRLKYHWYLLRCWVNQRWRREEKCYLYDSFVSYNSADESWVLQKLVPELEHGAFRLCLHHRDFQPGRSIIDNIVDAVYNSRKTVCVVSRSYLRSEWCSLEVQLASYRLLDERRDILVLVLLEDVGDAELSAYHRMRRVLLRRTYLRWPLDPAAQPLFWARLKRALRWVEGGEEEEEEGAGGETLKKWSVALGPQNCSWDAT chTLR2_2 2 chicken Gallus gallus Q9DGB6 781 chTLR8 8 chicken Gallus gallus "chr1:116,625,014-116,637,247" unknown gaps in draft sequence hide TIR domain and preclude a good gene model Scaffold TLR Evalue TIR Evalue intestinalis scaffold_187 1.00E-34 5.00E-70 must be a TLR (allele of scaffold 743 TLR?) scaffold_743 3.00E-32 8.00E-70 must be a TLR (allele of scaffold 187 TLR?) scaffold_193 6.00E-12 3.00E-13 definitely a TLR scaffold_24 10000 0.007 hard to read much into the TIR alignment; could conceivably be a real TIR scaffold_430 3.00E-04 0.021 could be a TLR scaffold_13 0.006 0.065 probably not a TLR as TIR hits are remote from tlr hit scaffold_134 2.00E-06 0.15 "seems more likely to be a SLIT than a TLR, but could be a TLR" scaffold_833 8.00E-04 1.6 not a TLR; no TIR by inspection scaffold_204 2.00E-18 2.8 not a TLR; ortholog to RIKEN cDNA 1810038N08 [Mus] scaffold_44 1.00E-04 4 not a TLR; might have a TIR by inspection; ortholog to LRRC15 Gene Models scaffold_187 or scaffold_743 >genscanv1.1303.2.1 MLKLPGRDINPLYKVRCFGMSVIPTGTLPPVEIMDLSGNSLTQIESRSFQFCCASVSYTTWLSFANNFLTKVGNGSFDCFVSLKNLSLQLNSLVQLEAGTFHGLYGLETLLLKSNLFKEIPYESLKRLDNLETLDLSGNSFNSFAFGDYFSQKNKPRSLKKLYLADMDDLNIHKSPESCCGGSCRTYYEVLDFRQLYNVKMDTELFRCYHIDNLYFSDFPMLYEPSILDALRCSHVNNLHVNMGGEQAKQRHIHLTDASFKGLTYQSCNETIVRRIGLNFAQVTEVRKFVFSNIKGLEYIDLSKNQIHRVDPEAFANVDNLRGINISHNNLQSVPMIKYTYNVTLIEYIDLSWNKIFQDKISIGIAPKRFKSIYSQTKSVVLAGSWFTYAFADYGVSALESLNISHCKIGWFDLGHMSQLSALRLRVMDVSYNNLLEIPIDWLKYLHHLEYFDFSGNHVVYNDEVNNAFKHHVNLTCIKFNQVLNIEQGLNTGIMFSGLMVKQLYFIRSNIRSISSSAFTGSVHLRLLDVSYNKITGLEKNIFQTNHLLEELNLRGNQIRVLDPPNTFSSLVNLRSLDIENNRFLCNCDIIPLQQWIIDNLYLTVGRSRILLRNVTCFLHSSRSYVDIIEWDSEALCWKKATKIVGIVLGCLLLSTACAVFGFSVRFQALFWYEMIKSKLSYHKALPRNRSDVYEYQAYLSCVPDSVDEAWVVRQLLCAIENPPYELTPMKLCFPSRDFKPGCPKMVSAANNLRLSKHALVILSKDYVANSWTRFELSMVSEMWRNSERSAESLIVVYLKRHGESLVGVERLPVLGVRRNAWLVWPTDVADRPSFWMKLRRSLAK scaffold_187 or scaffold_743 >SP.10453.IPI00019006_from_IPI_based_GeneWise PMRLWFPSRDLKPGCPTMVSAANNLRLSKHALVILSKDYVANSWTRFELSMVSEMWRNSERSAESLIVVYLKRHGESLVGVERLPVLGVRRNAWLVWPTDVADRPSFWMKLRRSL scaffold_193 >genscanv1.58.23.1 MPLSLRTLQISSCKIPWPRVSIRWPRNINHLTVIYCKVETTDPTTFKDLVRVDFLSMRGNLMTDVPFGLPQTTKTLDVSYNRMRTVSDNVWGGLNNLTKLYISNNQLVSIPKYLPSSLEQLNLKENQISYSDRDALERLVNLRQLDMSYNSTIQTQEVSIFLAVTSVLLRGNPLECNCKLRPLITWIQTNEKNEQNLSTHDLKDLICFTPKRFEGRYIINLSESEYCPVVNLSLIGGLVGGFTALLIIIIIIVNIYLYKKRKKQERRDIVQGFKDLLEKEAMNEGDPETGVGVAPVTYEYDAFVSYVSDSDDVEFVYKMLEEMEEKRERKMCIHERDFTPGRGIADNIVECISTSRRMVLVVSRKYASSAWCQYEVQIALTELHAKRRGRLLVPILLEDVTRDEQYAGSVTTILSAITAIQAPKAQDNDRTWTNFWNKLDKTLT Genbank My short name TLR Digit Species common name Species scientific name Accession # NA Not a TLR sea squirt Ciona intestinalis AAP91723.1 located on scaffold_88 (best hit is a glycoprptein; no TIR) Scaffold TLR Evalue TIR Evalue savignyi separate_scaffold_14408 8.00E-35 5.00E-89 must be a TLR separate_scaffold_27967 9.00E-33 5.00E-89 must be a TLR separate_scaffold_14863 6.00E-37 6.00E-89 must be a TLR separate_scaffold_16592 8.00E-26 6.00E-89 must be a TLR separate_scaffold_19449 4.00E-41 2.00E-88 must be a TLR separate_scaffold_16593 5.00E-12 3.00E-88 must be a TLR separate_scaffold_12854 1.00E-13 9.00E-77 must be a TLR separate_scaffold_21070 6.00E-09 2.00E-74 must be a TLR separate_scaffold_14137 4.00E-08 1.00E-61 definitely a TLR separate_scaffold_24874 3.00E-14 3.00E-59 must be a TLR separate_scaffold_27085 5.00E-32 1.00E-56 must be a TLR separate_scaffold_22568 5.00E-14 2.00E-37 must be a TLR separate_scaffold_14862 10000 2.00E-28 could be a TLR TIR domain separate_scaffold_30965 10000 2.00E-20 could be a TLR TIR domain separate_scaffold_31412 5.00E-13 3.00E-14 must be a TLR separate_scaffold_33579 3.00E-12 2.00E-13 must be a TLR separate_scaffold_10867 10000 6.00E-05 might be a TLR TIR domain separate_scaffold_30655 0.008 0.002 is a TLR (or perhaps a TLR pseudogene?) separate_scaffold_20424 0.007 0.005 is a TLR (or perhaps a TLR pseudogene?) separate_scaffold_31762 6.00E-09 0.22 probably not a TLR as the TLR hit and the TIR hit are separated by 127 kb Gene Models > Cs21.7 MLDMSRNSIREISNHTFSSSCEAFKVTRILDLANNLISGIEADSFSCFTGLEYLHLQLNF IANIDQWTFRDLEKLKLLNLKANNLIEIPRQAIRSLLALESLYLGGNRFQDFVFDDYFSN PHRPPGLKHLYLVGLTDLNITGRQGEVCKHVTYYETIDLTLTTNLVLSKNLFACYQIGTL HLSDYPYLIDPLRMKALKCTTIGTLDFGPGWRNEHPGIMALTNKTFAALKCLNSSSIVHR IRIRNTQLHALKNFSFSEVAGLQYIDLSHNKLSSIHAAAFSNVSTLREIDLSNNDLQTFP VLHYSPMVHSIQSINLARNKIFSDGFSLDVVQRNGQRSLYSQTRAINVAENWFRYVLATV SISETESINISHCKIEWFDLGGIYTLEKIPLRIMDLSYNRFVELPPSVLPRLPKLEYFDF SGNSIRHILNCTVFWRNVNLTYIAFNEVHNIQSYLNSGMFSHLNVKFLFLSKSSIRNISS NAFHGSEHMRTLDLSMNKISMIPGSLFRDNLMLEIINLQGNQISQLDPAVFTLLTRLGSL NIQNNPFFCECAIIPLQQWIIKNTFSSPPNRNRIFFGKMTCFLQKSHIYLDFLRWDAEKQ CWMKTTIVVGILLASCLLGSCFVVFLYFSRFHMLFWYEMIKAKISFQRKVAMDTSNAFKY QAYISCVPDSKDEAWVVRHLICAIENPPYELAPMNLCFPSRDFRAGCPKMASAATSIRTS KHTLVVLSPEYVRNSWTRLELSMVSEMWLNSERSAESLVVVYLKRRGEDLVDIERLPVLG VRRNCWLTWPLDVSDRPAFWMKLRGSLAK > Cs28.14 MRLERTIIASCIVFSTVRIAASITWAASNCTIKVTSGRFVPRRYYVNCSNLRMPDLPRGR LPTVGVLDMTGNSVTTVGVESFRSSCGAFKATRTLDLSNNLISSIHNDSFGCFVALERLH LQLNNIDILFRWVFRGLAKLKVLNLSANSLVEVPQQSIGGLPRLESLDLSANPLHDFVFD DHFSKRNKPPALKRLYLVGLHDSNIKGGRGGARCSNVAFYEIIDLSQTNRVALSKRLFAC YKIGTLYLSDYPYLTLPRSMEAFQCSTVDSIDIRFGLRSNRPMPQALDRTVFSGLQCANL STTVRGIRIRYTTIKTVGGYTFSDVTGLRRIDLSHNKLASVHSAAFSDVPSLREIDLSNN NLQRVPFLLRSSTPRTFDRISLAWNKIFDDTLSFYITATTEQASLYNQARYVDLAGNWFT SFRSGEIDTALEGINVSRCKIQDLEKGSLPLLTNITLRTLDLSYNRIAAFPTDWLRHLTH LEHVDYSGNRVLHSPFPVKAFRNNHNLTHVAFNQVDGIQRSLNAGMFSGLKVKFLFLSKC NIRQISSSAFNGSTHMKVIDLSWNKISMIPGSLFRHNPMLEVINLRGNRISQMDPAAFAF LAHLRSLDLQNNRFLCDCDIVPLQQWIIENTYTTARHRRRILFQNATCFQQSSHAYLEML RWDAGKQCWMKSTVVTGIAFASVLLAVCCVAFAYSSRFQALFWYEMVKAKISYRRKVPAD AFGGNEYNAYISCVPDSNDEAWVVRHLLSAIENPPYELEPMKLCFPSRDFRPGRPKMASA ASGIRSAERTLVVLSAGYARCSWTRLELSMVSEMWRSGERSAESLVVVYLKRRGEDWVDV ERLPVLGVRKNRWLIWPLEVADRPAFWMKLRRSLMR > Cs35.19 MRLERMIIASCIVFSTVRIAASITWAASNCTIKVTSGRFVPRRYYVNCSNLRMPDLPRGR LPTVGVLDMTGNSVTTVGVESFRSSCGAFKATRTLDLSNNLISSIHNDSFGCFVALERLH LQLNNIDILYRWVFRGLAKLKVLNLSANSLVEVPQQSIGGLPRLESLDLSANPLHDFVFD DHFSKRNKPPALKRLYLVGLHDSNIKGGRGGARCSNVAFYEIIDLSQTNRVALSKRLFAC YKIGTLYLSDYPYLTLPRSMEAFQCSTIDSIDIRFGLRSNRPMPDALDGTVFSGLQCANL STTVRRIRIRYTTINTVGGYTFSDVAGLRRIDLSHNKLASVHSAAFSDVPSLREIDLSNN NLQRVPFLLRSSTPRTVDRISLAWNKIFDDTLSFYITATTEQASLYNQARYVDLAGNWFT SFRSGEIDTALEGINVSHCKIQDLEKGSLPLLKNITLRTLDLSYNRVAAFPTDWLRHLTH LEYVDYSGNRVLHSPFPVKAFRNNHNLTHVAFNQVDGIQRGLNAGMFSGLKVEFLFLSKC KIRQISSSAFNGSTHMKVIDLSWNKISMIPGSLFRHNPMLEVINLRGNRISQMEPAAFAF LAHLRSLDVQNNRFLCDCDIVPLQQWIIENTYPTARHRRRILFENATCFQQSSHAYLEML RWDAGKQCWMKSTVVTGIAFASVLLVVCCVAFAYSSRFQALFWYEMVKAKISYRRKVPAD AFGGNEYNAYISCVPDSNDEAWVVRHLLSAIENPPYELEPMKLCFPSRDFRPGRPKMASA ASGIRSAERTLVILSAGYARCSWTRLELSMVSETWRSGERSAESLVVVYLKRRGEDWVDV ERLPVLGVRKNRWLIWPLEVADRPAFWMKLRRSLMR > Cs28.11 MRLERIVITSCIVFFMVRIAASITWAASNCTIKVTSGQFVPHRYYVNCSNLRMPDIPRGR LPMVGVLDMTGNSVMTVSVKSFRSSCGAFKVTRTLDLSNNLISSIHNDSFSCFVALERLH LQLNNIDILFRWVFRGLAKLKVLNLSANSLVKVPQQSIKGLLQLESLYLSANPLHDFVFD DYFSKQSKLPALKRLYLVGLHDSNITVGRGGACCSNVAFYEIIDLSFTNRVALSKYLFAC YKIGTLYLSDYPYLTLPRSMEAFQCSTIDSIDIRFGLRSNHPMPYVLNGTVFSGLQCAYL STTVRRIRIRYTTINTVGDYTFSNITGLQHIDLSHNKLATVHSAAFSNVPSLREIDLSNN NLQRVPFLLRSSTPQTIDRISLAWNKIFDDTLSFYIAATTERVLLYNQARYVDLAGNWFT SFASRKIDTVLESINVSYCKIQTLLKGSLPLLTNINLRTLDLSYNQIAAFPTDWLRQLIH LEYIDYSGNRVLHSPFPVKVFRNNHNLTYIAFNQVEGIQRSLNAGMFSGLNVKFLFLSKC NIRQISSSAFNGSTHMKVIDLSWNKISMIPESLFRHNPMLEVINLRGNQISQMDPAAFAF LAHLRSLDVQNNRFLCDCDIIPLQQWIIENTYTTVRHRRRILFQTATCFQESSHAYLEML RWDAGKQCWMNSTIITGIILASILLVVYCVVFMYSSRFQALFWYEMVKAKISYRRKVPAG TFGGNEYNAYISCVPDSNDEAWVVRHLLSAIENPPYELEPMKLCFPSRDFRPGRPKMASA ASGIRSAKHTLVILSAGYARCSWTRLELSMVSEMWRSSERSAESLVVVYLKRRGEDSVDV ERLPVLGVRKNRWLIWPLEVADRPAFWMKLRRSLMK > Cs28.17 MRLERTIIASCIVFSTVRIAASITWAASNCTIKVTSGRFVPRRYYVNCSILRMPDLPRGR LPTVGVLDMTGNSVTTVGVESFRSSCGAFKATRTLDLSNNLISSIHNDSFGCFVALERLH LQLNNIDILFRWVFRGLAKLKVLNLSANSLVEVPQQSIGGLPRLESLDLSANPLHDFVFD DHFSKRNKPPALKRLYLVGLHDSNIKGGRGGARCSNAAFYEIIDLSQTNRVALSKRLFAC YKIGTLYLSDYPYLTLPRSMEAFQCSTIDSIDVRFGLRSNRPMPHALDGTVFSGLQCADL STTVRRIRIRYTTINTVGGYTFSDVAGLRRIDLSHNKLASVHSAAFSDVPSLREIDLSNN NLQRVPFLLRSSTPRTVDRISLAWNKIFDDTLSFYITATTEQASLYNQARYVDLAGNWFT SFRSGEIDTALEGINVSRCKIQDLEKGNLSYNRIAAFPTDWLRHLIHLEYVDYSGNRVLH SPFPVKAFRNNRNLTHVAFNQVDGIQRSLNAGMFSGLKVKFLFLSKCNIRQISSSAFNGS THMKVIDLSWNKISMIPGSLFRHNPMLEVINLRGNRISQMEPAAFAFLAHLRSLDVQNNR FLCDCDIVPLQQWIIENTYTTARHRRRILFENATCFQQSSHAYLEMLRWDAGKQCWMKST VVTGIAFASVLLVVCCVAFAYSSRFQALFWYEMVKAKISYRRKVPADAFGGNEYNAYISC VPDSNDEAWVVRHLLSAIENPPYELEPMKLCFPSRDFRPGRPKTASAASGIRSAERTLVI LSAGYARCSWTRLELSMVSEMWRSGERSAESLVVVYLKRRGEDWVDVERLPVLGVRKNRW LIWPLEVADRPAFWMKLRRSLMR > Cs28.18 MRLERMIIASCIVFSTVRIAASITWAASNCTIKVTSGRFVPRRYYVNCSNLRMPDLPRGR LPTVGVLDMTGNSVTTVGVESFRSSCGAFKATRTLDLSNNLISSIHNDSFGCFVALERLH LQLNNIDILYRWVFRGLAKLKVLNLSANSLVEVPQQSIGGLPRLESLDLSANPLHDFVFD DHFSKRNKPPALKRLYLVGLHDSNIKGGRGGARCSNVAFYEIIDLSQTNRVALSKRLFAC YKIGTLYLSDYPYLTLPRSMEAFQCSTIDSIDIRFGLRSNRPMPDALDGTVFSGLQCANL STTVRRIRIRYTTINTGGGYTFSDVAGLRRIDLSHNKLASVHSAAFSDVPSLREIDLSNN NLQRVPFLLRSSTPRTVDRISLAWNKIFDDTLSFYITATTEQASLYNQARYVDLAGNWFT SFRSGEIDTALEGINVSHCKIQDLEKGSLPLLKNITLRTLDLSYNRIAAFPTDWLRHLTH LEYVDYSGNRVLHSPFPVKAFRNNHNLTHVAFNQVDGIQRGLNAGMFSGLKVEFLFLSKC KIRQISSSAFNGSTHMKVIDLSWNKISMIPGSLFRHNPMLEVINLRGNRISQMEPAAFAF LAHLRSLDVQNNRFLCDCDIVPLQQWIIENTYPTARHRRRILFENATCFQQSSHAYLEML RWDAGKQCWMKSTVVTGIAFASVLLVVCCVAFAYSSRFQALFWYEMVKAKISYRRKVPAD AFGGNEYNAYISCVPDSNDEAWVVRHLLSAIENPPYELEPMKLCFPSRDFRPGRPKMASA ASGIRSAERTLVILSAGYAKCSWTRLELSMVSEMWRSGERSAESLVVVYLKRRGEDWVDV ERLPVLGVRKNRWLLWPLEVADRPAFWMKLRRSLMR > Cs28.15 MRLERRIIASCVVFSTVRIAASITWAASNCTIKVTSGRFVPRRYYVNCSNLRMPDLPRGR LPTVGVLDMTGNSVTTVGVESFRSSCGAFKVTRTLDLSNNLISSIHNDSFGCFVALERLH LQLNNIDILFRWVFRGLAKLKVLNLSANSLVQVPQQSIGGLPRLESLDLSANPLHDFVFD DHFSKRNKPPALKRLYLVGLHDSNIKGGRGCARCSNVAFYEIIDLSQTNRVALSKRLFAC YKIGTLYLSDYPYLTLPRSMEAFQCSTIDSIDIRFGLRSNRPMPHALDGTVFSGLQCANL STTVRGIRIRYTTIKTVGDYTFSNVAGLRRIDLSHNKLASVHSAAFSDVPSLREIDLSNN NLQRVPFLLRSSTPRTVDRISLAWNKILDDTLSFDITATTEQVSLYNQARYVDLAGNWFT SFRSGEIDTALEGINVSHCKIQDLEKGSLPLLTNITLRTLDLSYNRIAAFPTDWLRHLTH LEYVDYSGNRVLHSPFPVKAFRNNHNLTHVAFNQVDGIQRGLNAGMFSGLKVKFLFLSKC NIRQISSSAFNGSTHMKVIDLSWNKISMIPGSLFRHNPMLEVINLRGNRISQMEPAAFAF LAHLRSLDVQNNRFLCDCDIVPLQQWIIENTYTTARHRRRILFENATCFQQSSHAYLEML RWDAGKQCCMKSTVVTGIVFASLLLAVCCVAFAYSSRFQALFWYEMVKAKISYRRKVPAD AFGGNEYNAYISCVPDSNDEAWVVRRLLSAIENPPYELEPMKLCFPSRDFRPGRPKTASA ASGIRSAERTLVILSAGYARCSWTRLELSMVSERRAIGRIAGRRLPEATRGRLG > Cs35.12 MRLERMIIASCIVFSTVRIAASITWAASNCTIKVTSGRFVPRRYYVNCSNLRMPDLPRGR LPTVGVLDMTGNSVTTVGVESFRSSCGAFKATRTLDLSNNLISSIHNDSFGCFVALERLH LQLNNIDILFRWVFRGLAKLKVLNLSANSLVEVPQQSIGGLPRLESLDLSANPLHDFVFD DHFSKRNKPPALKRLYLVGLHDSNIKGGRGGARCSNVAFYEIIDLSQTNRVALSKRLFAC YKIGTLYLSDYPYLTLPRSMEAFQCSTIDSIDIRFGLRSNRPMPYALDGTVFSGLQCADL STTVRRIRIRYTTINTVGGYTFSDVAGLRRIDLSHNKLASVHSAAFSDVPSLREIDLSNN NLQRVPFLLRSSTPRTVDRISLAWNKIFDDTLSFYITATTEQVSLYNQARYVDLAGNWFT SFRSGEIDTALEGINVSHCKIQDLEKGSLPLLTNITLRTLDLSYNRIAAFPTDWLRHLTH LEYVDYSGNRVLHSPFPVKAFRNNRNLTHVAFNQVAGIQRGLNAGMFSGLKVKFLFLSKC NIRQISSSAFNGSTHMKVIDLSWNKISMIPGSLFRHNPMLEVINLRGNRISQMEPAAFAF LAHLRSLDVQNNRFLCDCDIVPLQQWIIENTYTTARHRRRILFQNATCFQQSSHAYLEML RWDAGKQCWMKSTVVTGIVFASILLVVCCVAFAYSSRFQALFWYEMVKAKISYRRKVPAD AFGGNEYNAYISCVPDSNDEAWVVRHLLSAIENPPYELEPMKLCFPSRDFRPGRPKMASA ASGIRSAERALVILSAGYARCSWTRLELSMVSEMWRSGERSAESLVVVYLKRRGEDWVDV ERLPVLGVRKNRWLIWPLEVADRPAFWMKLRRSLMR > Cs2811 MRLERIVITSCIVFFMVRIAASITWAASNCTIKVTSGQFVPHRYYVNCSNLRMPDIPRGR LPMVGVLDMTGNSVMTVSVKSFRSSCGAFKVTRTLDLSNNLISSIHNDSFSCFVALERLH LQLNNIDILFRWVFRGLAKLKVLNLSANSLVKVPQQSIKGLLQLESLYLSANPLHDFVFD DYFSKQSKLPALKRLYLVGLHDSNITVGRGGACCSNVAFYEIIDLSFTNRVALSKYLFAC YKIGTLYLSDYPYLTLPRSMEAFQCSTIDSIDIRFGLRSNHPMPYVLNGTVFSGLQCAYL STTVRRIRIRYTTINTVGDYTFSNITGLQHIDLSHNKLATVHSAAFSNVPSLREIDLSNN NLQRVPFLLRSSTPQTIDRISLAWNKIFDDTLSFYIAATTERVLLYNQARYVDLAGNWFT SFASRKIDTVLESINVSYCKIQTLLKGSLPLLTNINLRTLDLSYNQIAAFPTDWLRQLIH LEYIDYSGNRVLHSPFPVKVFRNNHNLTYIAFNQVEGIQRSLNAGMFSGLNVKFLFLSKC NIRQISSSAFNGSTHMKVIDLSWNKISMIPESLFRHNPMLEVINLRGNQISQMDPAAFAF LAHLRSLDVQNNRFLCDCDIIPLQQWIIENTYTTVRHRRRILFQTATCFQESSHAYLEML RWDAGKQCWMNSTIITGIILASILLVVYCVVFMYSSRFQALFWYEMVKAKISYRRKVPAG TFGGNEYNAYISCVPDSNDEAWVVRHLLSAIENPPYELEPMKLCFPSRDFRPGRPKMASA ASGIRSAKHTLVILSAGYARCSWTRLELSMVSEMWRSSERSAESLVVVYLKRRGEDSVDV ERLPVLGVRKNRWLIWPLEVADRPAFWMKLRRSLMK > Cs28.9 MPDIPRGRLPMVGVLDMTGNSVMTVSVESFRSSCGAFKVTRTLDLSNNLISSIHNDSFSC FFALERLHLQLNNIDSLFRWVFRGLGKLKVLNLSANSLVKIPQQSIKGLLQLESLDFSAN PLHDFVFDDYFSKQNKPPALKRLYLVGLHDSNITVGRGGACCSNVTFYETIDLSFTNRVA LSKYLFACYKIGTLYLSDYPYLTLPRSMEAFQCSTIDSIDIRFGLRSNHPMPYVLNGTVF SGLQCAYLSTTVRRIRIRYTTINTVGDYTFSNITGLQHIDLSHNKLASVHSAAFSNVPSL REIDLSNNNLQRVPFLLRSSTPQTIDRISLAWNKIFDNTLSFYIAATTEQVLLYNQARYV DLAGNWFTSFASRKIDTILESINVSHCKIQTLLKGSLPLLTNITLRTLDLSYNQIAAFPT DWLRQLIHLEYIDYSGNRVLHSPFPVKAFRNNHNLTYIAFNQVEGIQHSLNAGMFSGLNV KFLFLSKCNIRQISSSAFNGSTHMKVIDLSWNKISMIPESLFRHNLMLEVINLQGNQISQ MDPASFAFLAHLRSLDVQNNRFLCDCDIIPLQQWIIENTYTTVQHRHRILFQTATCFQQS SHAYLEMIRWDAGKQCWMKSTIITGIILASILLVVYCLVFMYSSRFQALFWYEMVKAKIS YRRKVTADTFSGNEYNAYISCIPDSNDEVWVVRHLLSAIENPPYELEPMKLCFPSRDFRP GRPKMASVASGIRSAKHTLVILSAGYAKCSWTRLELSMVSENVAERRAIGRIA My short name TLR Digit Location Species common name Species scientific name Accession # Seqeunce dogTLR1 1 chr3_15.70 chr3:76722359-76724308 dog Canis familiaris MSQLEFLGLSATQLQKSSMLPIASLHIRKVLLVLGDTYGKKEDPESLQKLNTESLHIVFPIRKEFSFTLDVSVSTAVSLELSNIKCVPDGHGWSYFQNVLSKLQKNSRLSSLTLNNIETTWNFFIMLLQLVWHTSIEYFSISNVKLQGYPDFRDFDYSDTSLKALSIHQVVSNAFNLPQSYIYKIFSNMNIQNFTVSGTHMVHMVCPSQISPFLHLDFSNNLLTDIVFKNCRNLIKLETLSLQMNQLKELASIAQMTNEMKSLQQLDISQNSLRYDENEGNCSWTRSLLSLNMSSNILTDSVFRCLPPKVKVLDLHDNRIRSIPKPIMKLEDLQELNVASNSLAHFPDCGTFNRLSVLIIDSNSISNPSADFLQSCHNIRSISAGNNPFQCTCELREFVQSLGQVASKVVEGWPDSYKCDSPENYKGTLLKDFHVSPLSCNTTLLLVTIGVAVLVFTVTVTALCIYFDLPWYLRMVFQWTQTRRRARNTPLENLQRTIQFHAFISYSGHDSAWVKSELLPNLEKEELRICLHERNFIPGKSIVENIINCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHNLFHEGSNNLILILLEPIPQYSIPSSYHKLKNLMAQRTYLEWPKEKSKHGLFWANLRASINIKLREQAKK dogTLR2 2 chr15_11.34 chr15:54493328-54495685 dog Canis familiaris MSRVLWTLWVLGAVTNLSKEEAPDQSSSLSCDPTGVCDGRSRSLNSMPSGLTAAVRSLDLSNNEITYIGNSDLRDCVNLKALRLESNGINTIEEESFFSLWSLEHLDLSYNLLSNLSSSWFRPLSSLKFLNLLGNPYKSLGETPLFSQLTNLRILKVGNIYSFTEIQDKDFAGLTFLEELEIDASNLQRYEPKSLKSIQNISYLALRMKQPVLLVEIFVDLSSSLKHLELRDTHLDTFHFSEASINETHTLVKKWTFRNVKVTDRSFTEVVRLLNYVSGVLEVEFEDCTLYGLGDFDIPDVDKIKNIGQIETLTVRRLHIPHFYSFYDMSSIYSLTEDVKRITVESSKVFLVPCSLSQHLKSLEYLDLSDNLMVEEYLRNSACQHAWPLLQTLILRQNRLKSLEKTGETLLTLKNLVNLDISKNNYLSMPETCQWPEKLKCLNLSDTRMQSITRCIPQTLEILDVSNNNLESFSLILPQLKELSISRNKLKTLPDASFLPTLQIMRISRNTINAFSKEQLDSFHRLQTLEAGGNNFLCSCEFLSFTQEQQALAGLLVGWPEDYLCHSPSYVRGQRVGTARLPASECHRTALVAAVCCVLLLLVLLTAGACHHFHGLWYLRMLWAWLQAKRKPRKAPSRDVCYDAFVSYSEHDSYWVENLLVQKLEHFNPPFKLCLHKRDFIPGKWIIDNIIDSIEKSHKTIFVLSENFVKSEWCKYELDFSHFRLFDENNDAAILILLEPIEKKAIPQRFCKLRKIMNTKTYLEWPTDDAQQEGFWLNLRTAIKS dogTLR3 3 "chr16_9.55 chr16:46,214,201-46,221,367 " dog Canis familiaris MDVLGVGVGKPQDGGLEDTVPGRSSGIQKGVSVLQCKDLTENPAQQGLLVVSLRRWSMADAGLILGEEDFKGKTNKGTAISGCTMQQNKTRNNEKDILPTSPQMTVYWAFAQGSHQSTAVVSGTMLTSAPTGPNTPTARHPPTQGTTYLEVFRVPGERPGWSREGLRIPDARVPASDPVCPGTYGHQAVTGSKCHQMVIFTDKISFTFEIAGNLPFFPGENNWIWTNEKKEWSAVIRANEDQTFVFCVNLTELHLMSNSIKIIQNNPFRSLKNLVKLDLSHNGLSSTKLGSQLQLENLQELLLSNNKINVLRREELDFLGNSSLEKLELSSNPIKEFSPGCFHAIGKLFGLSLNNVQLNPSLTENLCLELSNTSIQNLSLSNTQLHRTSNMTFLGLKHTNLTMLDLSHNNLNVIENNSFVWLPHLEYFLLEYNNIEHLFSHSFYGLLNVRYLDLKRSFAKQSTSLASHPRIDDFSFQWLKCLQYLNMEDNYFAGIKSNMFTGLIKLKHLSLSNSFTSLQTLTNETFLSLAQSPLITLNLTKNKISKIESGAFSWLGHLQVLDLGLNEIGQELTGQEWRGLENIVEIYLSYNKYLQLTSSSFALIPSLRRLMLRRTALRNVDSSPSPFHPLRNLNILDLSNNNIANINDELLEGLEKLEILDMQHNNLARLWKHANPGGPVHFLKGLSHLHILNLESNGFDEIPAEVFKGLSELKSIDLGLNNLNIFPSSLFNDQVSLKSLNLQKNLITSVEKNVFGPAFRNLSNLDMSFNPFDCTCESIAWFVNWINSTHTNISELSSHYLCNTPPQYHGFPVMLFDISPCKDSAPFEIFFIINTSVLLTFIFIVLLIHFEGWRISFYWNVSVHRILGFKEIDKQPEQFEYAAYIIHAYKDRDWVWEHFSPMEEKDETLKFCLEERDFEAGVLELESIINSIKKSRKTIFVITQHLLKDPLCKRPLLFTLPDIGEERTSDSDSEGGREAYPTLFVFTLTSPCLSSTRFFSFAHTPHYLFLHFWCELHNYHLVKGLTLFVLKIKEFLTVVQMETSTYQYTQTQVCREVIGSDTIKHLCENGERDPEGAQLDLEFLLIRFASCIYQGTRGFLRASPPRKPPRILTHSEYSVRFRQAFKAEMQNYERFDHTNVEFLQGKRTEEFDKANAQKVQQLFWEVEEMLFEGKVSPQTQNLVAECSEWARRSLHLRVLGRQLIVPTDEGFQHFQGSEPRSALHKPFLDACGHNHNSREDDECLEQKSAHRHRMWHKHGLPPVSPHDCIKDAVAAEVFDHVWTNVVEILEELIRKNWEVTLTEGKKQKEKLKVAENKSPLLHISRINTDAPSVPPSRSSEARSLSLASHLNPPQVHRFSNNFYSDLSGVMTIQAKPLQQRPTYFADRTQNEQEDRSLGTGAGAISLARHRLGRISDARVLHTSGKKTPAHTRLPSLTSDSQRMKTPNVYSDEVLRGTKLQTGGDRVSSSSAQASRSRLPPIGSETCEQNMAVPGSRPVSLDTPRKGSLTLMEFAGHSWTSQSFLTEDNSDYKKEIPGGILMELGLKLQSLTMPLSLEKWKNKYYTVYLSDSEM dogTLR4 4 chr11_14.100 chr11:72715920-72745708 dog Canis familiaris MKSTMYLSTEALEHRQEILGGRNGKEKAQDNHRVSYRSRSTWYEKITGLSVQGTLKDARLVMVSKETLLGTENARMMSPTRLVGILIPAMAFLSCLRPESWDPCMQVVANTTYQCMELNLSKIPNNIPTSTEKLDLSFNPLRHLGSHCFSNFPKLQVLDLSRCEIQVIEDDAYQGLNHLSILILTGNPIQRLFPRAFSGLSSLKTLVAKETKLTSLEDFPIGHLKTLKELNVAHNLIHSFKLPAYFSNMPNLENVDLSNNKIQNIYREDLQVLHHMPLLNLSLDLSLNPLYFIQPGSFKEIKLHKLTLRSNFNSTDVMKTFIQGLAGLKINQLVLGEFKNERKLESFDNSLLEGLCNLTIEKFRIAYFDSFSKDTTNLFNQLVNISAISLAHLYLDTPKYLPKNLRWQRLEIVNCNLEQFPAWELDSLKEFVLTSNKGMNTFADMKMESLEFLDLSRNRLSFKTCCSHSDFGTTRLKHLDLSFNEIITMSSNFLGLEQLEYLDLQHSSLKQASDFSVFLSLRNLRYLDISYTRTEVAFQGIFDGLVSLEVLKMADNSFPDNSLPNIFKGLTNLTILDLSRCHLERVSQESFVSLPKLQEINMSHNSLLSLDTLAYEPLLSLQILDCSFNRIVAFKEQGQQHFPSNLVSLNLTRNNFACDCEHQSFLQWVKDHRQLLVEVEQMVCAKPLDMKDMPLLSFRNATCQRSKTIISVSVFTVLMVSLVAVLAYKFYFHLMLLAGCKRYNRGESTYDAFVIYSSQDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIAANIIQEGFYKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSRAGIIFIVLQKVEKSLLRQQVELYRLLSRNTYLEWEDSVLGRHIFWRRLRKALLDGKPWSPEGTEDAEKS dogTLR5 5 "chr38_4.21 chr38:18,938,163-18,945,461" dog Canis familiaris MTGALSRAALAPTGLGRGWEGDALTRQAGRFADGGPKDQRVRADPGRVWSAQGAEGRAPGTGRGRHQYPPPAIFPDALHASRLSDGKQTLLKVSVSQGPSTALSARPAGRTCGGRQVPVQGPPSWAPGWRWACTAVFPSRRIMGRQLGRALGLLLVAGAVAAASCCVADGRRALYRSCNLSQVPPVPSTTEILLLSFNYIRAVTRASFPLLERLQLLELGTQQTPFSVDREAFRNLPNLRTLDLGNSRVDFLHPDAFQGLPHLQELRLFACGLSDVVLTDGYFRNLGALSRLDLSKNQIGSLELHASFRELGSLRSVDFSLNRIPAACEQGLRPLQGKALSLLNLAANGLYSRAPVDWGRCGNPFRNVVLETLDVSNNGWTADVTGNVTRAIGGSQISSLVLAHHIMGQGFGFRNIRDPDRSTFAGLAGSSVLRLDLSHGFVFSLNARLFEVLGDLKLLDLAHNKINRIAGEAFHGLGSVQVLNLSHNLLGELYDSDFSGLAEVAYIDLQHNHIGIIQDQTFRFLGALRTLDLRDNALKTVSFVPSIDTIFLGNNKLETVSHMDLTASFLELSDNRLEDLGDLYSLLRVPALQVLILNRNRLSACRGGHGPTGSVGPERLFLGSNMLQLAWETGRCWDVFRGLPRLRVLHLNHNYLAALPPGLLRDLTALRGLDLSANRLSTLSRGDLPAALEVLDVSRNQLLSLDPGLLAPLRAVDLTHNKFICGCELRPLVRWLNRTNVTVFGSRADVRCAYPSLLAGTPLSSVSMEGCDDEEALRTLTFSLFIFSTVGVTLFLLAVLVAAKLRGLCFLCYKAARRLLPAGPAEDGAPDAYQYDAYLCFSGRDFEWVQRALLRHLDAQYSSRNRLNLCFEERDFVPGREHIANIQDAVWSSRKVVCLVSRHFLRDGWCLEAFAAARSRCASHLDGALVLVVVGSLSQYQLRRHPAIGGFVRQRRYLRWPEDLQDVGWFLDTLSRHILQEQRGARGDGGIPLRTVAAVA dogTLR6 6 chr3_15.69 chr3:76700388-76702782 dog Canis familiaris MIKDKDSITGSFHFVYIVTLIVGTIIQFSDESEFTVDMSNMNLTHVPEDLPPKTKILDMSQNNISELHLSDMSYLSGLKILRISHNRIWWLDFSIFKFNQDLEYLDLSYNQLRNMSCHLIRSLKHLDLSFNDFHVLPICKEFGNLTQLQFLGLSATKLRQLDLLPIAHLHLSYILLDLQGYYAKESEKGSLQILDTKTLHLVFHPNQLFSVQANICLPPKVKVLDLHDNRIRSIPKPIMKLEDLQELNVASNSLAHFPDCGTFNRLSVLIIDSNSISNPSADFLQSCHNIRSMSAGNNPFQCTCELREFVQSLGQVASKVVEGWPDSYKCDSPENYKGTLLKDFHVSPLSCNTTLLLVTIGVAVLVFTVTVTALCIYFDLPCEHDSAWVKNELVPCLEKEELRICLHERNFIPGKSIVENIINCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHNLFHEGSNNLILILLEPIPQNCIPSKYHKLRALMTQRTYLEWPKEKSKHGLFWANIRAAFNMKLTLIAENNNAEAS dogTLR7 7 chrX_2.123 chrX:9251638-9270561 dog Canis familiaris MLKGDRPYLSKGFLYTLAYCHLPRDLIPPDWKVFPMWTLKRQFFILLNIILISKLLGARWFPKTLPCDVSLDAPKAHVIVDCTDKHLTEIPGGIPSNATNLTLTINHIPGISPASFHQLDYLVEIDFRCNCIPVRLGPKDHLCTRRPQIKPRSFSSLTYLKSLYLDGNQLLEIPEGLPPSLELLSLEANSIFSIMKNNLTELTNIERLYLGQNCYFRNPCNVSFFIEKDAFLSLKNLKLLSLKDNNITYVPTTLPSTLTELYLYNNAIAKIQEDDFNNLNQLRILDLSGNCPRCYNVPFPCTPCENNSPLQIHESAFDALTELQVLRLHSNSLQRVPQRWFKNIKKLKELDLSQNFLAKEIGDAKFLYLLHDLVQLDLSFNYELQVYRAALNLSDAFSSLKNLKVLRIKGYVFKELSSHHLSPLQSLTNLEVLDLGTNFIKIADLSIFEQFKTLKVIDLSMNKISPSGDSGEVGFCSSTRTSVEGHAPQVLETLHYFRYDEYARSCRFKNKETPSFLPFNKDCYMYGQTLDLSRNNIFFIKSSDFQHLSFLKCLNLSGNTIGQTLNGSEFQPLVELKYLDFSNNRLDLLYSTAFEELRKLEVLDISSNSHYFQSEGITHMLNFTKNLKVLKKLMMNNNDIATSTSRTMESESLKILEFRGNHLDVLWRDGDNRYLKFFKNLLNLEELDISENSLSFLPSGVFDGMPPNLKTLSLVKNGLKSFHWERLQYLKNLETLDLSYNELKIVPERLYNCSRSLKKLILKYNQIRQLTKHFLQDAFQLRYLDLSSNKIQIIQKTSFPENVLNNLEMLLLHHNRFLCTCDAVWFVWWVNHTEVTIPYLATDVTCVGPGAHKGQSVVSLDLYTCELDLTNLVLFSFSLSLALFLMVITTANHLYFWDVWYSYHYCKAKIKGYRRLKSLDSCYDAFVVYDTKDPAVTEWVLDELVAKLEDPREKHFNLCLEERDWLPGQPVLENLSQSIQLSKKTVFVMTNKYAKTENFKIAFYLSHQRLMDEKVDVIILIFLEKPLQKSKFLQLRKRLYPELAPHGGLPTCHCLFALGPVAGSLVEIVLSPSHPNQDGWETRVALLGEVGNGDGEKVPSVLCIFRLRPSEQRALARGRAHPSWDSGCQGSGAAGDPKEHWGPLRSSEGEQNQPISLTWWEEGGQEPKRPTPHWQGEPRQLKYPVRLYRARYGLNTDSSPPTHPDAFIREMVASAEQAAKETGRSKRVVNVNLKLSKDRLGFPRAGTVAANATLWFKQRWNPSYMSPALPLSTSLAEHPPLVALNNLTINHSPLPPCPPSHRHLSAAEQYTLAPGGVKIQHLPNSVPIAWTCRLGTLRFPNSVELTHPGTGRKPEMQASNPDNVGCRHGNGPQTRNKAFIHVRIFIHFYGDLKFHTPVAASRTNDPSAWFRETEIVGRERHLVAARLLTPLPLAGSSRSSVTSKEVPQALWGAEAQGKKQKWSFPTLRTPLLFSCRLFPKARLFPGSGMEPVPRADTLAPKDPASPPLSQRNWRLPDTHLFQCRMFCVTVSGTFAQNQDSSPEEPVHPDAYPVPQGELGPP dogTLR8 8 chrX_2.125 chrX:9295241-9298357 dog Canis familiaris MSPRSLVLTCLFLLISDSYEFVTKANYSRSYPCDERRQNGSVIAECNGRRLQEVPQTVGKYVTVLDLSDNYITHITNESFHGLQNLTKINLNHNANPQHLSENPDNKNGMNITDGAFLNLQNLNQLLLEDNQLYQIPAGLPGSLKELSLIQNNIIWVTKKNTSGLTNLERLYLSWNCYFGNNCNNKTFNIEDGTFESLTNLEVLSLSFNKLVHVPPKLPSSLKELYLSNAKIKIISQEDFKGLRNLRVLDLSGNCPRCFNAPFPCTPCEGGASIQIHPLAFQTLTELRYLNLSSTSLRKIPATWFDNMRNLKVLHLEFNYLVDEIASGEFLTKLPVLEILDLSYNYVKAKYPKYINISHNFSSLKLLQALHLRGYVFQELRAGDFEPLMGLSNLKTINLGVNFIKQINFTLFQNFPNLSIIYLSENRISPLVNDIRQNEVNSSSSQRHVLKPRSADMEFDPHSNFYHNTHPLIKPQCTVYGKALDLSLNSIFFIGREQFEAFHDIACLNLSSNGNGQVLHGNEFSAVPHIKYLDLTNNRLDFDDDNALSDLPELEVLDLSYNAHYFRIAGVTHRLGFIQNLTQLKVLNLSHNSIYTLTEQDLRSVSLEELVFSGNRLDILWNAEGDKYWKIFTRLRNLTRLDLSLNNLRRIPNEAFLNLPQSLTQLYIKNNALNFFNWTLLQEFPHLQVLDLSGNRLSSITNSLSKFTSSLQTLLLHRNRISHLPASFLSEASSLIHLDLSSNLLKMINKSTLQTKTNTSLAILELGRNPFDCTCDIGDFRRWMDENLNVTIPRLTDVICSSPGDQRGKSIVSLELTTCISDTLAAVLCIFTSFITVTVMLAALGHHWFYWDVWFIYHVCLAKVKGYRSVSTSQTFYDAYVSYDTKDASVTDWVINELRFHLEESEGKNVLLCLEERDWDPGLAIIDNLMQSINQSKKTIFVLTKEYAQNWNFKTAFYLALQRLMDENMDVIIFILLEPVLQHSQYLRLRQRICKSSILQWPDNPKAEGLFWQSLKNVVLTENDSRYNNLYVDSIKQY dogTLR9 9 "chr20:40,393,972-40,396,942 " dog Canis familiaris BAC65192.3 Toll-like receptor 9 protein MGPCRGALHPLSLLVQAAALALALAQGTLPAFLPCELQPHGLVNCNWLFLKSVPRFSAAAPRGNVTSLSLYSNRIHHLHDYDFVHFVHLRRLNLKWNCPPASLSPMHFPCHMTIEPNTFLAVPTLEDLNLSYNSITTVPALPSSLVSLSLSRTNILVPDPATLAGLYALRFLFLDGNCYYKNPCQQALQVAPGALLGLGNLTHLSLKYNNLTVVPRGLPPSLEYLLLSYNHIITLAPEDLANLTALRVLDVGGNCRRCDHARNPCRECPKGFPQLHPNTFGHLNHLEGLVLRDSSLYSLDPRWFHGLGNLMVLDLSENFLYDCITKTKAFYGLARLRRLNLSFNYHKKVSFAHLHLASSFGSLLSLQELDIHGIFFRSLSETTLQSLAHLPMLQRLHLQLNFISQAQLSIFGAFPGLRYVDLSDNRISGAAEPAAATGEVEADCGERVWPQSRDLALGPLGTPGSEAFMPSCRTLNFTLDLSRNNLVTVQPEMFVRLARLQCLGLSHNSISQAVNGSQFVPLSNLRVLDLSHNKLDLYHGRSFTELPRLEALDLSYNSQPFSMRGVGHNLSFVAQLPALRYLSLAHNGIHSRVSQQLRSASLRALDFSGNTPSLMWAEGDLYLRFFQGLRSLVQLDLSQNRLHTLLPRNLDNLPKSLRLLRLRDNYLAFFNWSSLALLPKLEALDLAGNQLKALSNGSLPNGTQLQRLDLSGNSIGFVVPGFFALAVRLRELNLSANALKTAEPSWFGSLAGALKVLDVTANPLHCACGATFVDFLLEVQAAVPGLPSRVKCGSPGQLQGRSIFAQDLRLCLDEALSWVCFSLSLLAVALSLAVPMLHQLCGWDLWYCFHLCLAWLPRRGRRRGVDALAYDAFVVFDKAQSSVADWVYNELRVQLEERRGRRALRLCLEERDWVPGKTLFENLWASVYSSRKTLFVLARTDRVSGLLRASFLLAQQRLLEDRKDVVVLVILCPDAHRSRYVRLRQRLCRQSVLLWPHQPSGQRSFWAQLGTALTRDNRHFYNQNFCRGPTTA dogTLR10 10 chr3_15.71 chr3:76748113-76750428 dog Canis familiaris MSLRKIPADLTPTTTTLDLSYNLLSQLQSSDFRSVSKLKVLILCHNRIQELNIKIFEFNRELRYLDLSYNRLKIVTWYSLAGLRHLDLSFNDFDTVPICEETGNMSHLEILGLSGAKIQKSNFQKIAHLHLKTVFLGLRSLSHYEEGSLPILNTTKLHIVLPMNTNFWVLLHDGIKTSKILEMTNIDGKSQFASYGTQKNLTLENSKTSILLLNKVDLLWDDLLLIFQFVWHTSVECFQIQHLTFGGKVYLDHYSFDYSNTVMRTIKLEHVQFRIFYIPQERVYLLFTKMDIENLTISDAQMPYMLFPIYPTRFQYLNFANNILTDDLFKQPIQLPHLKTLILKGNKLETFSLVSFFANNTSLKHLDLSQNLLQHENGENCFWPETLITMNLSSNKFADSVFRCLPRNIQILDLNNNKIQTVPKDIIHLKSLQELNLAFNFLTDLPGCSHFRKLSILNIEMNLILSPSLDFFQSCQEVKILNAGRNPFRCTCELRDFIQLEEYSEGMMIGWLDSYICEYPLTLKGTLLKDVHLPELSCNTTLLIVTIVVIMLVLGMAVAFCCFYFDLPWYLRMLGQWTLQRIRKTTQEQLKRNVQFHVFIAYSEHDSTWVKHELIPNLEKKEKLICLHEGNFDPGKSIIENIMNCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHSLFHENSDYIIFILLEPIPLYCIPTKYPKLKALMEKKAYLEWPKDRRICGLFWANLRAAINANLLETREMYELQTFVGLNEESQGSAISLIRTDCL Probable Pseudogenes dogTLR11 11 dog Canis familiaris AGHGLPDCSIIDSSLLPNISYYIPFSSLAPGMDLFASCSNVKDQVQTLTEVPLGHTSYPAE.CLCTLPHNTAEVTAGRP.DCIYDI.RIGLQLNISFEHHAPYYWSLFLPPDALELLNTLSFHGHHLNSSHRLHLPISFSHLTLKHSCLMEQKL.GFFPNLVFGFSPTTSHSHGSPFLEVLDLSANLKLSWVHNRALHGLQFHCLR.DGIPLNALELDSGLFHLDSLSLVETDGEKLPENVAGYFELHALNLGRNQIQNTKEMYFPSCDFLELLSFHASGLQLPPSRFLSALT.LQRLNLSMNKLGPTLVLPRGLVSSNLKLLYLSHNELSVLPYRAFSPVLLFQWLWLSVNYYLQLNLESLEGLK.LKT.DLSWNQIKLLKLGWLSSLPATTAHLTPWAAIQSIRTTLYVLSCQDLRSPWCNLKLRLTTYHLVAKPGTCLLPIAVSGIFSH.LQLQSYYHLAWRLQEKTNIFVPREIK.DDFCEQL.KRLRKSGQKRED. dogTLR12 12 dog Canis familiaris XP_544422.1 PREDICTED: similar to toll-like receptor 12 MTDPILVSGTPATPSSLCWCPFKCQSRLRPTGGPSLTPGQKCGRPGCQARLGRRGGRRGQARRPGLLALCGTSAAGAGLCAGLCAGLCAEGARPPGSRPGRCSRRCPSACRKRRPRSGAAALAAPGVPHPAPPNYQSGSLQKGILTNSGAISQAPLKHFYERLNEGDELSSGTCLSFLATGNELFVLKGFPKLRSKEFSGIMQLAVKYSCFQNVGELANIVLDLGLSCFSGDAWTLGMLDLSFTTWLKVASPGALQGLQLGTPCLDHEGGSLWWLQRLYLSGNRLWSAVLCTNGTGAVSGLQALDLYNKRGWLAPLLTLITLNLLGTHMVLSLALNFYGSENLHTLRLQFPSPSSRVELSLLTSLELSAVSDKEFWKLASLAFSVLQTLTAKGEALQLETRNIAKIFLTLCQLSLLGNTWRLYAPRVPLVSSSGSSPGPSSCGMGGQTGAGDTACCCFQSPGSLQVLVLDWETGLMLHGSLQEHSPQITQYVYILGASLACQCAMLLLVFLEPVSHHHLPGYCGLAWLLCRGDFSFSLPLFISPYFCCDVSPAHLSRVFPEAGPAPFSLSARPLGGAIISEPVERTGVAIGSALKNRSCSDLFRCPRPGEDDTPIG Genbank My short name TLR Digit Species common name Species scientific name Accession # Length (AA) dogTLR2 2 dog Canis familiaris NP_001005264 dogTLR4 4 dog Canis familiaris NP_001002950 636 dogTLR9 9 dog Canis familiaris NP_001002998 Rainbow Trout ESTs AB062504 "Oncorhynchus mykiss TLR5 mRNA for Toll-like receptor5, complete cds" gi|28972009|dbj|AB062504.1|[28972009] AJ628348 Oncorhynchus mykiss mRNA for Toll-like-receptor (tlr gene) gi|47678173|emb|AJ628348.1|[47678173] AF281346 "Oncorhynchus mykiss putative Toll-like/IL-1 receptor mRNA, partial cds" gi|11095784|gb|AF281346.1|[11095784] Rainbow Trout ESTs from TIGR "TC47862 similar to SP|P58681|TLR7_MOUSE Toll-like receptor 7 precursor. {Mus musculus;}, partial (4%) " "TC50354 similar to SP|Q9QZ06|TLIP_MOUSE Toll-interacting protein. {Mus musculus;}, partial (96%) " "TC51262 similar to GB|AAF78035.1|8575525|AF245702 toll-like receptor 7 {Homo sapiens;} , partial (3%) " "TC61840 weakly similar to UP|AAQ91310 (AAQ91310) Toll-like receptor 5a (Fragment), partial (71%) " "TC67442 UP|Q7ZT81 (Q7ZT81) Toll-like receptor5, complete " "TC68587 weakly similar to UP|BAD01045 (BAD01045) Toll-like receptor 3, partial (3%) " Atlantic salmon ESTs from TIGR "TC30555 homologue to UP|Q7ZT81 (Q7ZT81) Toll-like receptor5, partial (42%) " "TC32326 weakly similar to UP|TLR4_HORSE (Q9MYW3) Toll-like receptor 4 precursor, partial (3%)" Other amby salamander Ambystoma tigrinum CN059792.1 EST hagfish1 hagfish Eptatretus burgeri BJ647133.1 VLR EST hagfish2 hagfish Eptatretus burgeri BJ655662.1 VLR EST sback1 three spined stickleback Gasterosteus aculeatus CD505894.1 EST sback2 three spined stickleback Gasterosteus aculeatus CD505605.1 EST sback3 three spined stickleback Gasterosteus aculeatus CD504027.1 EST trout1 trout Oncorhynchus mykiss BX882819.1 EST trout2 trout Oncorhynchus mykiss CA379121.1 EST lamprey lamprey Petromyzon marinus CK988491.1 likely VLR EST lamprey lamprey Petromyzon marinus CO552675.1 likely VLR EST lamprey lamprey Petromyzon marinus CO552495.1 likely VLR EST lamprey lamprey Petromyzon marinus CO552300.1 likely VLR EST lamprey lamprey Petromyzon marinus CK988545.1 likely VLR EST lamprey lamprey Petromyzon marinus CO548222.1 likely VLR EST lamprey lamprey Petromyzon marinus CK988464.1 likely VLR EST lamprey lamprey Petromyzon marinus CK988520.1 likely VLR EST lamprey lamprey Petromyzon marinus CK988494.1 likely VLR EST lamprey lamprey Petromyzon marinus BX879818.2 likely VLR EST lamprey lamprey Petromyzon marinus CO552352.1 likely VLR EST lamprey lamprey Petromyzon marinus CK988642.1 VLR EST lamprey lamprey Petromyzon marinus CK988506.1 likely VLR EST lamprey lamprey Petromyzon marinus CK988495.1 likely VLR EST lamprey lamprey Petromyzon marinus CK988489.1 likely VLR EST lamprey lamprey Petromyzon marinus CK988592.1 likely VLR EST finch zebra finch Taeniopygia guttata CK313318 likely VLR EST kfish killifish (Percomorpha) Fundulus heteroclitus CN981200 EST similar to Insulin-like growth factor binding protein complex trout2 TLR3-like? trout Oncorhynchus mykiss TC54038 ESTMy short name TLR Numerical Deisgnation Species common name Species scientific name Scaffold # Sequence Xt 1L1 frog Xenopus tropicalis MLSIYILVQSESSKASFIHRRLPRGLSNCPSADTQLDFTKRNITQLQTSDFSCFLDLKFLNLSYNSIEELDCSVFQFNPSLEYLDISNNRLHTIQCQSLQYIKHIKHLDLSYNNFKQMHFCKEFTALSQLKHLGLSAEQIQTNSFLNIAPMQLEYVFLGMEDLTEYENGSLQFLNTNKLLINLPTNLNLASSYLLSDALNTSTTLEVSGAQCDVHCDYFTKSFSTITKNSKVVNLIISNGAMPGNEIFKIMPPIWDSSIEHLYIKIFRLQNELKYVKMDFLHHSIKSLTVEDLTNEVVSFRDTHPLQMFAEMLVENITFSRAELYFFFCPPAPSIFRVINLPSNRLTDDIFQNCANLKELELLNLQNNKLEQMSKISSMTLTMPNLKHLDLSRNGLHIDNEKQCKWMDSLVFLNLSESGLTNSVFGCLPINLQILDLSKNQISSIPIEVKNFVSLKELHLASNRLTDIPDCHNIGNNLGVLKVDENLINLPSKEFLQNCEYVKYLSAGKNPFQCNCDLREFVKMGVMFPKRLIGWPESYKCADPENLRGIFLQDFYLPEISCNISMLLGVVLGTIFILSIIVVSACFYFDVPWYIRMLFRWFRTKHRLRNVNQQDIQNDKLFHAFISYSQEDSDWVKNMLLPNLERKDGSIKICHHERHFIPGKAIIENIIDCIEKSFKSIFVLSPNFIQSDWCHYELYFAQHTLFGKNSNNLILILLDPIPQYLIPNKYNKLRSIMKHRTYLEWPKEKGKHALFWANLREAIHVNLSIKEEDMADPEVRT Xt 1L2 frog Xenopus tropicalis MAAIFFLLIYLSSSGQCVRQEIFESHIANYSNKFLFAVPKNLSSLTTVLDISFNSIATMETSEFNYIFDLQVLNASYNKMKYLNSSIFKFNTQLQYLDFSHNVLRNISGTFPSHIQHLDISFNNFQTLSVCSGFGNMVLLEYLGLGADQILKSDFEGIVHLHLKEVFIELNSLNDYENGSLLLLNTKKLTLDFGVLSNEDRYNVLFDAVNTTSVLELSHLQRWNIHIDPKKYIFNIVQNSKVTDLTMRHVNVEWKMIVLALQYIWHSSVETLTFYDFSLKGLIAKTSFDYSNTSVKAVNVQGVNVGVFQFDQSSVYRVFSNMNIENLTLNFASLLFMVCPLNSSTFQSIDFSHNALTDDLFKDCFTLINLKRLKLRKNKLEKIYKLSAMTENMPSLEYLDASHNLLAYDEEDCHWSQNIVELNLASNFLTASIFKCLPISIKILILESNDITHVPSGVTHLDDLVELNLSFNRLGDLPDCSNISSLSLLGVEGNQILYPSIESIESCSRVKHISAGQNPFQCNCELRRFINQEKEAPGTLIGWPEAYVCKYPDHLRGTMLKDFYISEITCNVFILIPVIILPIIISIALIIGLCKYLDGPWFLKMIWQYTRTKQRTRTSKQGYQSLQRDFDFNAFISYSEHDASWVKNIFLPSIERSNDCIRICQHERNFIPGKSIIENIINCIEKSYKSIFILSPNFVQSEWCHYELYFAHHKLYTENNDNLILILLEPIPQYLIPSKYYKLKTLMAQRTYLEWPSEKSKHGLFWANLRAAISIDLTHAESEIPYSISSENPCSISSENPHSISSENPYSISSDNPCLGTSENPCSISSENPYSISSENPC Xt 1L3 frog Xenopus tropicalis MRVHAAEYNLYFLFAIIIYILAQFESNKALIIQRKLHKCFSSCPSVCTLLDFTKENITHLKTSDFNCFLQLRLLNLSHNLIGELDCSVFKFNPSLEYLDISNNRLHTIKCHSLQYIKNIKRMDLSYNNFKTMDFCSEFTALSQLKHLGLSSKKIQKDSFINIASMDLDFVFLGIENEIEYENGSLQFLNTNKLHINLQPNLSLASSYLLSDALDTSMTLEVSGAQCDVHCDYFTKSFFTINKNSKVVNLIISNSTMPGNEMLKIIPPIWDSSVEHLHIKMFRLIKEFKYVKMDFTHHSIKSFTLEYFTNDVFFFQGTHPFNIFAEMLVENVTFSNAGMIHFFCPPVPSIVRFLNLPSNRITDEIFLNCSSLNELELLNLQNNKLEQMSKISSMTLKMKNLKHLDLSKNGLHIDNEKQCNWMDSLVFLNLSESGLTNSVFGCLPINLQILDLSKNQISSIPIEVKNFVSLKELHLASNRLTDIPDCHNIGNNLGVLKVDENFINLPSKEFLQNCEYVQYLSAGKNPFQCNCDLREFVKMGVMFPKRLIGWPESYKCADPENLRGIFLQDFYLPEISCNISMLLGVVLGTIFILSIIVVSACFYFDVPWYIRMLFRWFRTKHRLRNVNQQDIQNDKLFHAFISYSQEDSDWVKNMLLPNLERKDGSIKICHHERHFIPGKAIIENIIDCIEKSFKSIFVLSPNFIQSDWCHYELYFAQHTLFGKNSNNLILILLDPIPQYSIPNKYNKLRSIMKHRTYLEWPKEKGKHALFWANLREAIHVNLSIKEEDMADPEITIT Xt 2 frog Xenopus tropicalis MMQSISLSCLILSLVVTVLSKGNTDCPCDAAHFCHCSSMHWEAIPSGLPRDVRGLNLSSNAIQIVTETDLQPYDQLQTLLLQYNAIHTINDGSFQPLGNLEELDLSYNNLSHLSSAWFRNLYNLKHLNLLGNQYLTLGNNSLFASLSSLRSLQFGNQDFSAIQKLHFESLERLNILEIKAAQLGLYEEGSLAAIKQINHAVLTVNIQNLRALLNDFVHSVTLLEMKDMQFGDAADVKAMVILNDTSIKYLVFRNCIITDQSASRLLEIFQTYRNITDFILDDSTLYGTGTASPVIGDDPFSVTTAIINKLHIPKFFLFSDLQGIYKLASNFKNIACIDSKVFLMPCAFSRSFSSLQYLDLSGNLLSDNLLASSACAFEGGGAWPILQTLNVSRNLLTSLRRLAQITSGLKYLTNLDVSQNNFGELSTSTCQWPKSLKYLNISSSQMSNITCIPPTLQILDVSSNYLTVFTIKMPNLTELYISNNRLSKLPEGMYFPRLFMLSIDRNKLNDFYQSDLDLFPQLTTLDGRDNNYLCSCQFLSFMHSHTIALVGWPDDYICDSPSSVRGKRIQDANLPPLVCHKTLIVTLSCILLIALVAAIAALCHFLHVVWYAKMTWAWLKAKRKPLKNCDREICYNGFVSYSERDSEWVENMMVPKLENAVPPMKLCLHKRDFVPGKWIIDNIIDAMEKSYKTVFVLSEHFVRSEWCKYELEFSHFRLFDENNDSAILILLEPIENETVPKRFCKLRKLMNTKTYLEWPTDEEQQEVFWDNLKTALQSEY Xt 3 frog Xenopus tropicalis MGQLWLSLHILYAIYGMSLVAGNPCKITEDLTADCSHLKLSAIPSDLPRNIKALDLSHNQLKKLPAANLSVYDQLERLDAGFNTLHQFEPALCKQLLMLKTLNLEHNEFTKISENDFTFCVHLSELHLASNGISNIDGNPFEKLENLLFLDMSHNKMISTALGNKQQLKNLKELYLNSNKISKLNKEAFEFLANTSLQKLDLSSNPLTEINPGCFQAIGSFAALVIQNTQLDPQRTEQVCSELAHTGVLNLTLNNIRLSKIRNTTFKGLADTNLTVLDLSGNSLSQIDNDSFVSLGALEILNLENNDISHVNPKTFNGLSKVRVLNLRKSLSSNLKLDDLSFQSLHNVQYLNMEANKMIAITEHTFIGLTSLTNLSLSDSTLQQHTLTNRTFLSLSKSPLYHLNLTKTGLTKIENGAFLCLKHLQLLDMGLNQIDQEVSGNELEGLANIEMIYLSYNRRITLTSNSFIFAPSLSKLYLRKTALTFRDLNPSPFKVLQNLTVLDLSNNNIANIQEDVFESLSNLRILSFEHNNLARLWKEANPGGPVLFLKGLKNLEKLSLLSNGFDEIPANAFKGLCKLKVLDIGENNVYILPPSVFDDQHSLTLLDLHKNLITSVEQDLFKNVFSSLKYLNMGGNPYDCTCESIAWFASWLNTTNTSVPLAHSQYICNTPARYHGNPVDTFDSSPCKELAPFRLFVSTFSLMLVFILSVLLIQFQGWRINFYWTVSINRILGFKEIDPRKRNFDYDAYIIHAQNDVSWVENHLIPLEKNAGSKLQFCFEERDLEAGTSTLSAFVDCINRSRKTIFVVTRNLLNDSWCRRFKVQHAFQQAIEQNRDSIILIFLEDIPDYKLYHTIHLRRGMFKSRCILDWPDQMERIKTFYQRLKIALGSTNLVN Xt 4 frog Xenopus tropicalis HFFVAITLYLKVVFLHRCSITVIEDLAFFGLNILQTLVFTGNPRSHWAPLSFFGLFSxhklivvetslssltelplrnitslrelyaghnklksllftsllvnldlhgnqiteikdndldlirgvmktslslilscnpihyfspkafmdinlhklqiqgcfsnaeslrsnlkvlsgskiekleigdyrssavkisfqeglmeglcradiqelsingmyfpardtpldcvkystslcvvnnnleldniiqsneifdrlqsvyiknctltnipslflskcpslrevritgiqklsnfnreltglrelkvldfsnnqlnmnyyctqlvagtkesriqhlnlsynsfigfdsafinmphlqsldlihskiqtvgkfpvfmllinfldlsytychfpidcsfcglyrleelrvsrstfagdilsvvfqnltkllslhlsecslefipkgtflslkvlnvlnlsknklldlqtsmliplsnlisldlnfnqfkvisdnsirslpsslakvdlsgnpfdcscwqiifllwvqqqkdkllkqsyqmfcktpntlnglpltdftpncsmtalisetvlgilcpsliaitgklicnkckrnhdnnyvydafvmysnadqlvpklenengfiiclhyrdfvpgvpivtnisnsilnsqkvsvvlsqtfleskwcnfefemakawqslegsfqiivillexinktqlkkalglhkylakttylelnkdlffwlrlqnslkngq Xt 5 frog Xenopus tropicalis LCSFFLFRVTLFYKLIAIIGGSALAFGQIPKCTTTNRIAYFFYCNLTHMPPVNSDTLVLDLSFNYLSEVNSTFFPRLLQLVDLNLGSQQTERLIVKKDSFRNTPSLVKLDLAYNQLLILDSDGLAGLSQLKILFLYYNKLNGSILENDYFKDLMSLEYVDLSSNEITYLRPNPLFYHLYSLDIINLRHNQISSICAGDLHSFERKYFTIMELSHNRFNKWEMLGSDRCGNPFRNIEFDTLMLSGTGFDVDKMQKFCGALNGTKMMQLKLDSHGMGAGFGYNHIKDPDNSTFVGLVNSNLQILDLSTGNIFSLKPYTFGNLTVLKLLNLAENKINRIENKAFCGLNSLITLNLSYNLLGELYDYSFEGLPDLTxidlqqnhigaiqnnafksleklnyldlrgnamkkvtffealipityiffggnklksidssyvystfldlsendlndlgglfkilqypllqyvilkrnrlsvcyshfsisknnsllhldlsdnminliwdngqclnvfsnlsllgllklnnnflrylpdgifngleslqtlnlssnllthlmpgvfptnldtvdlsknqlyspspkvflsvkkldlthnqyicdcflldfimwlnetnatllgspydtycmyppnflfqplhiltvencdddkvlmplmfslfvltsttilvlmstvvtythyrgfcfatykrilgliignekkeeaadackydaylcysskdfqwvqdaflrnldtqycdrnrfrlcfeerdfipgedhivnirdaiwnskkticivqsssdgwslslnyaqsryftelkdvlimvvvgslsqyqfmkyqpirayvkraqylrwpediqdvewflgrlsyqilkentvekkpnqasrkpfnhelqnietis Xt 7 frog Xenopus tropicalis MRRQLLFFLISILSFSGLLATNWFPKSLPCDVEQNAKGNVIVVDCSDRHLTSIPWGIPTNVTNLTLTINHIPRISVDSFAEFTNLVELDFRCNCVPAKVGPKDHVCTKRLDVEDRSFASLYNLRSLYLDGNQLIEFPKGLPPNLQLLSLEINNIISISRNNLSELSNIQMLYLGQNCYHRNPCSDSFKIEKDAFKDLKNLSILSMKSNNLSFVPGGLSDSLKELYLYNNAIQYIEEHDLENLINLEILDLSGNCPRCYNSPFPCTPCPNNAPIQIHPKAFSSLKNLQVLRLHSNSLRSIPEQWFKNNRNLQVLDLSENFLASEISTANFLKYIPSLKSLDLSFNFELQVYPSDLKLSSIFSSLASLETLRIRGYVFQNLKKNNLMPLVHLPNLTLLDLSTNFIKVADFSLFPKFKSLQTIILSNNKISPSSEANIDSCSASQVSSGHYIGRTFQEVHYFEYDENARKCKAKDKENFTFKLFLNESCQAYGQSLDLSQNNIFFVKATDFTNLSFLKCLNLSGNAISQTLNGSEFRNLNRLKYLDFSNNRIDLLYSTAFQELTELEVLDISNNDHYFLAEGITHVFNFTKNLEKLTKLMMNNNQISTSTNRHLVSQSLRILEFKGNYLNILWKDGDTRYLNFFKNLNKLYKLDISENSLTFVPPGVFEGMPPDLLELYLARNKLKTFSWDKLHLLEKLSVLDLSNNYLTTVPRELSNCTSSIKKLILSNNKIKKLTPFFLRGSVSLKYLDLSDNLIQNIGHSSFPEDVLDNLTELLLQGNPFKCNCNLVWLVSWINQTKVYIPNLVTGVTCSGPGAHRGQSLVLLDLYTCEQYHLNLILQALSASFIICLMVVSVSSHLFYWDFWFIYHLFKAKIHGYKRFPKCCYDALIMYDTKDSAVSDWVFNDLVNILEKQGNKMLNLCLEERDFLAGQPFLDNLSESIQISRKTVFVLTRKYVKKGHFKTAFYMAHQRLIEEKVDVIILILLEKTLQRSRYLRLRKDYVQTLFYI Xt 8 frog Xenopus tropicalis IKLLFGLHSCNYYTANILFFSPQAKMTGSLQTLVLVVLITCNSLECSDTNPNNRTIPCKIAENGSSVSFDCSARWLQMVPYPIKYSSDSVELLLSQNLILTINNESFHSWHNLTKIDLNWNHYPKSRLDNADICKRGLEIENGTFSYLTKLEKLFIDHNYLCKIPQGIPSTLTFLSLSYNNIFSVKKQILSPLINLKNLFLSNNCYFGNECGQVLDIEEGTFSGLTELTELSLSFNNLTHVPSKLPASLKQLYLSNNNIQIINRNDFHNLVNLEVLYLSGNCPRCFNANYPCKNLCPNTSLKDHFAFQNLKNLTELHLSSTSLKTIPPTWFQNTTQLKKLYLERNYLVNEIASADFLLNLPFLEVLDLSFNYDLRSYTNNINISDHFSKLVSLKELHIQGYVFKHIAANNLAPLLNLSKLKILNLGTNFIRQVDFKIFQQFTGLELIYLSENRITPFSEKNNKMKLVEGYEDKHSRVSSPGVSFPTQFNFQMTKTFSEVVKPQCSSRGKTLDLSLNSIFFIDPKEFRSFSDVSCLNLSSNGIGQDLNGTEFIYLKNLTYLDLSFNKLDFDSINAFQELPSLEVLDLSYNSHYFIVDGVIHSLKFIENLQHLKVLNLSWNKISTLTDFRLTSHSLKELQFSGNRLDVLWKNEDKRYHKLFMNLSSLTCLDISYNRLSKIKGELRYLPLSLTELYLNNNELVYFGWEELQAYENLKYLDLSHNKLTMIMGNLSIHTYSLSSLIISYNSISSLPVAFLHKARNLSELDLSFNHLKSINSSVLLSGSENYLKVLGLKGNPFVCTCEITDFISWIYANNVTIPRLATDVNCATPENKKGSGIIYFDVHTCDLDGAAMILYFFSVFLVMSITVLPILINVFSWDLWYVYHLCVAKLRLHKVCKSECLYDVFITYDNKDPNVNDWIFNELCQHLEDKGDKHMYLCLEERDWEPGKAIIDNLAHSINQSKKTLFVLTKKYVKSGKFKIAFYLALQKLMDENMDVIVIVLLEPVLQNSQYLKLRRKICKSSIMEWPKNPNAKGLFWQRMKNVLLTDNCKRYNNFYTDPIENYE Xt 9 frog Xenopus tropicalis YLHLYNIVSLHAQQKRKVFLPLSLGLILGVCLAFCKIPHFLPCDDFNNASTVICRERQLIHVPHIVSQSVKVFDLAINEIRLLANSTFSGVPNLVILNLSDNCQPSNLRPYKEICRLIIEPHALVSLKSLTNLDLSGNSLTSIPPLPENIKFLNLNLNQIHMISGWEFSRLNNVKMIRLGYNCFYSKQCEPFHLSDSAFINNEFLEELALSFNNITSFPQNLPSSIRILDLSENKISKIDREDLCNLNNLYSLDLQWNCQRCDHALQACYPCKNNSALLLVPGVFDCLHKLSYLNLRGNSLHTLHSSLFSSLTNLSHLVLSDNFLNLETETFFSALTNVKELNLDFNFKPYSMYERLVLNSNVARMKSLERITIVGYFFNVLDEEGIMPLLSLPNLREISLRTNFILKVNLSMLFTHKPLRFISLSENLISFEEHKHGQKLAMHPPLFDRGNQVDGGWMDSHCGPKQVEAGEVEYPGCWQYNHSVDLSFNNIGSIYPDEFLGMDEIECLNMSYNYINQRLNGTQFGHLKSLRHLDLSHNRFDMYYYKALSELPRLKILNLAHNDYQFMMKGVNHRLDFLENLTSLVELNLNNNFIGLRITRELKSHSLETLRFRNNELGSSWQYGKDTYLNMFTNLRSLKILDISYNQLPVIPNEVLEKLPESLQKLNLSHNKLYTFNWAKTAHLGNLAILDLGFNALTKLRANLTESNIAFLNLTYNKINSLDKDFFDSFSELKQLILSNNLIKTIHITSFPINFLQNLDSLDVSGNPFQCTCKAYWFITFLMETEVTVDHLSTGMKCDSPDSLRGRSLLSMDPQSCQELYGHVCFIWSSILVIFLMVIPTIWNLFFWNLWYAGHLIVATLRSYTKLHDKSTEHFDAFIAFNTKNSSVRDWVYNELLVQLESPERGGFTLCLEERDWIAGRSSIENLYDSIYRSKKTIFIITREWFNCGLLRHAFFMSNQRLLDEKKDVVALVVLDHKMKMSQYFLTRKRLCPKSFLNWPCNPKAHSHFWHMLRIYIRQDSRRCCGSQLKKYVDK Xt 11 frog Xenopus tropicalis Sc568 (4/04 assembly); Sc892 (10/04 assembly) MDLCFKRKHWKTCYYLIGCILLFLPSISFGWTVKKCNVADRSMLLRDPMFATRCSLYKNATSLALCGNITNITADISDVPSTINILCLSGSNTFIPGGTFANFKRIKYLFMKMPLVRIYPNAFKGLESLESLAISFLGHSKCNNLSIPTDAFSNLYYLRDLSIEGFKLVKSMLIHLPFSTSLYSLSLPTNCITDLFHVFHIFQNLIFIHNLDVGSNKIERVSLQHDLNISLPNITELVLEKNPLILIQQNALARFGIHLLNLGFTKLNLEDILNAGVENLKSLSLTSACRRAINKTHTLCSIAQRFQLKSLSAPVNRFSGIYTKDFLGCSSLEFLNLNHNHIHIVDPDLLYTLPKLKELHLSYSLLHMNLCPLSYQDNFTSSVEALYFIGNRITVLKNKQFFCMTKLTDLLLARNGIEHIEESAFWGLNDLRVLDLRNNRLTSLQISSLSGLSNLMELYLQNNVMESMQRYSLKWQTKLRLVKIGFVSVSVSFELFPNTETLDIQTTGKYITVFMNETAASSLKSLSVNGSHVELDIKCGHQFFSTLRELKVINNNGLISCSHYGYQLEHFENLENIQYHFSGAPLTRNVNFSNIANLRSLEVENLATALDPNVPPNDLFHKLHKLEVLKLFNCGFKYMTTALLKDMRSLRVLVMKNQMILAVDPGLQNTLSPLEFIYFIDVTFQCDCDNSWFVTWALEDKHTFVSGICSLFCLQLNKKFNLVNFSESSCRQEIDFMLFVITFTSLLLFIVLTMLCNIFNSDIIQLFYVFQIWLKKLRGKTNNPIAYEYDAFVSYCSRDQGWVVNYLVPNLEEKGRNTIKLCLHNRDFLVGKDIVDNIMDSIYKSRKTICLISYNYLQSDWCSLEMRMATYKLLAEKNDDLILVFLESISGYHLSAYHRLARIVRKKTYIDWPQEENEQAEFWERLRMTVLETKED Xt 13 frog Xenopus tropicalis MPFHWTCPIAALMTLILQPISFIECYGYRKCSLEGIHTEYANCVGQSVVTLADAIQDLPYQTRVLNISENEISKIDGYTFSHLPKLQELVLRKNKVNGVDTWAFHNLNDLLILDLSYNLIQSLDTVDLTDLKHLQIFDLSHNRIHTIQMGTLGPLGALQELDLSFNNVSDFRSVANAVSQLPDFLRLSLSSNFITDLKSEQSVTVLSSLQSLNLRNNSISVLDFTFYSMPSLIELNVTRNNLSAVNKSSFSNLPMLAKVTFDENSLNISQLLGLVLPNLTEFHWSSMRPALQHELVSACQVFQTFPKLQLLDIKHSKIAVTNLSIIGRCTNLTSLILSTSPLPRLQEKDLQDFKYLEVLYLDKCKLRRIANSSWRGLNNLHTLILERNQLSDLEDKLFSPLTSLQYLDLSKNYLTHLNEKAFSGLRRLNYLSLKGCKITAATRNNFRYFSNLRVLDLQDNSISLIKSNAHIYLRKLETLLLSGNKILTIQKNGLKGLVSLKELSLANNNIYKITDNTFKFVKSLRSLDLSRNQLWPLHKFQSPTPFLNLTQLEYLDASYQAEGNIYIPASLFQGLQSLKVLRLQGNPSAFFRNVSFEFLLNLTELDISATVYTMTDPPISFEKELFKKLGQLRNLTLDNNGIQFLPEDVFTNVPMLEHISLRYNRLTNISEDILKNVPNLNYFDMYMNTLSCSCDNYWFQNWSKCNTEVQIPFIQSYKCFGLEANEMLFENQDFSFCTNTGYYFFLGSFIITFSLLTVNLLVVKLKWTVRYMYCMLEVWFRWKLETTDKVHKYDAYISYCEDDEIWVVEKLLHMLEEQGQRKFKLCFKPRDFVPGIYHLDNIQDAISNSRKTLCVVSRKYLESEWCREEMQLACSWAFSYKEDVLLMVFLEEIPEYR Xt 14 frog Xenopus tropicalis MEKLSHHERLVILCILALGLVERAQGQTPCKTDGIYANCKGRSLAAVPKDLPTTLVELDLSYNRLSHIQFDDFASFTHLRALNLSYNNISAIETGSFASNVLLTNLTLFNNSLTEMPSALFEPLRFLQFLDISNNFYNCATLGAEFSMLENLRNLSIGGPLVSKVLKGDFAPIKNISLQRFSLKTMSSLWLYEKGAFSDLNTQSLWLDIALDTNPQALPRMLKDLAGKAFSSLRFRNLFEFTYYTDAMDVFFGLADIFIKELTFYRGKFNENLLRLTLKNVEKSNIQDLFLLSIDFARSLSTNRTDIRINDLALRRLVIKDVTNPDILRFDWTFTWFNKVSHLDIINVNFNFVPCDAWSQMVNVERLDISNNRLLASNLYNLLCQYSELPNLHTFIASDNNMRSLYTLSLLTLTWPKLATLDLTSNYLGALDEVCTWTPQITKLILKDNTLKVGVFKCLPVTVEHLDMSNSLLERLDMDYFNRATKLKVLILSQNKLKFISRDWKCPNLQVLGLEGNSFSVIDKGSFKDLPELRRLTAGDNPYHCTCDLYAFFTETLTERRVSLADWPEEYNCYHPPHLLDTKVEFYNPGRVECDVRLVVAISVSTTAVVVMLCMLLCWRFDVPWYLRTTCSIVQSKYRSRSFHDSRDYNYHAFISYSHSDADWVRGELLYRLESCSPPYRVCIHERDFLPGRWIIDNIIENIESSRKIIFVLSRNFVNSEWCNYELYFAHQRAIGHAFEDVILVVKEKVTMEDLPKRFQKLRKMMRTKTYLEWPSEQNRQHFFWIQLKSILGKANPPVTSQETLSVVSETVAYGTCSVSETPSVPLGKVTLPSS Xt 14L1 frog Xenopus tropicalis Sc9853 MNPVLQNGQLGLWCVLVLGLVRELWCQTPCLVDESRRFVSCSGRNLVEIPKNFSVTLEELDMSFNRIFQIKSDDFSAYTNLRALNLSYNQIATIENGSFNSNTQLRSLTLFNNSLTEMPSALLEPLHLLEFLDMSNNFYNKSTLGDVFQTLVNLQTLSIGGPLVSKVQKDDFVPIRNIGLQKFALKTMSSLTLYEEGAFSVLNTHVLWFDIALDTNPQALLLILKDLKGKSFDVLRFRNLFEITYYTDTVDIFSWLPSISTRELVFYRGKFNENLLWIMLENIQRSSILDLSLLSVDFSRSHSANKTNVSIDDLRLRTLRVKDVTNPDILRFDWTFTWFRKISNLYIINVNFNSVPCDAWSEMSNLEKLDMSTDELVDTYLYNPWCQDVALPTTDTFILAYNNLQSLRMLSLLTAKWPKLATLDLRSNSLGSNDEMCTWTPSIRTVILKDNMLKVGVFQCLPTTVEFLDLSHSQLEQLDMDYFNKATNLKQLILSHNKIKFISSEWKSPNLQVLALEDNSFGVINVGSFKDLPKLRNLTAGDNPYGCTCDLYRFFSQIREEGRIVLADWPQAYKCYSPPDLLDTKVEFYNPGKVQCDVRLVVAISVSTTAVVVILSMLLCWRFDVLWYVQTMFAIVQSKYRSRNMGNTKDYLYHAFISYIENSRKIIFVLSRNFVNSEWCNYELYFAHQRAVGHALEDVILVVKEKVTMEDLPKRFQKLRKLLRTKTYLEWPLEHTRQHFFWIQLRSILGKVSSPVIGQDDLLVDNGAAASWDGPASEAHHEDEIYETLIPQ Xt 14L2 frog Xenopus tropicalis QVPFLQNLFFPNRCEDPGRVSAQQKVHVCFLLLNLLKWTSCQNPCQRDSTNRYANCQGQDLVEVPQDLPVTLQSLDLSYNRLFHIRYEDFSSYTNLRALNLSFNNISTIECGSFASNTLLRNLTLFNNSLTEMPSTLFEPLLLLEFLDVSNNLYNYSTLGKVFENLVNLQNLAIGGPLVSKVLKDDFAPIKNRSLKKFSLKTMSKLGFYEPGALEVLNTRVLWLDISLDTNAQALPLILKDLAGKTIDSLRFRRLFESSYYTDTMDLFCGLVDINIRELIFFRGMFTENLLHQALHSIQKSTIQDLLLLSVKFDRSLNTNNTHILFDRLYLNSLVIRDIAGPHIFKYDWTFTWFSKVRNLQLSRVHLGSLPCIAWRQMGNIECLDVSDNRLIGSNLYNPSCWDGGLPKLDTFIAANNNLQSLRLISLLTAKWPKLTKLDLSSNDLGVYNEVCTWIPNITTLILKGNTLKMCVFQCLPTSVELLDLSYSQLEQLDLNYFNRATNLKELVLSHNKLNFISSDWRSPNLQVLHLEGNSISLIDKGTFKDLPSLRRLTAGNNPYDCTCDLYAFFSTLQNNDEMLLADWPYDYQCFHPQHLRDTDVEDYTPWRVECDVSLVITISVSTTAAIIILCMLVCWRFDVPWYLRMTWRIVKSKYRSKKSNKSREYNYHAFISYSYSDADWVRGELLYRLESCSPPYRVCIHERDFLPGRWIIDNIIENIENSRKIIFVLSSNFINSEWCNYELYFAHQRAIGHSLEDIILVVKEKVTMEDLPKRFHKLRKMLRTKTYLEWPSEPSKQHFFWIQLKSILGDASVSLAGQEGLSVVNEAVVGPVFYLYHI Xt 14L3 frog Xenopus tropicalis MEMFRRYNEPVFYCFLLLALTKGIWSQNSCQVDEKQKYANCQGQNLNDVPKDLPVTLEVLDLSCNWISQIRVDDFSSYTNLQALNLSFNNISTIDNSSFASNTQLRNLTLFNNGLTEMPSTLLEPLLLLEVLDLSDNLYNYSTLGKVFKTLANLRSLSIGGPFVSKVLRGDFVPIKNISLQKFELKTRSSLRFYQTGAFSVLNTDVLVLVMTLDTNPKVLPMILKDLAGKSLDILSFGNLFEHNYYAGPTNPFSSLPDINVRELIFNRGKVNQKLLQLILETIQTSSIQDLSLLSVDFDYSDVRTTVDVKMDNLFLRSLVIKDATNPDILTFDQTFTWFSKVSNLYIINVNFNFAQCDTWSQMKNVERLDIRNNLLLSSDLYNPSCKYGELPKLHTFTAANNNLQILKPISLLTANWPKLSSLDLSSNYIGSEDENCSWTPNITTFILKNNLLTPGVFTCLPTTVRYLDLSNSRLESLDMDYFSNATNLKTLVLSYNKLTSISSNWSNPFLQVLFLDNNIISIIDKGSFNNLPQLRTLTAGNNPYHCTCDLYSFFSDVLGKNKITISDWPQSYCCYHPQQLRNTRVDIYTPGSIECNVGLLVAITVSTTAVVVIACMIMCWRLDAPWYFRMMCHIVKSKYRSKKANDSREYNYHAFISYSYSDADWVRGELLYRLESCSPPYRVCIHERDFLPGRWIIDNIIDNIETSRKTIFVLSHNFVNSEWCNYELYFAHQRAIGHSFEDVILVVKENVTLKDLPKRFHKLRKMLRKKTYLEWPSEPSKQHFFWIQLKNILGSPSTAGALEPCPASEVPSITYSKINLPGS Xt 16 frog Xenopus tropicalis MDLCFKRKHWKTCYYLIGCILLFLPSISFGWTVKKCNVADRSMLLRDPMFATRCSLYKNATSLALCGNITNITADISDVPSTINILCLSGSNTFIPGGTFANFKRIKYLFMKMPLVRIYPNAFKGLESLESLAISFLGHSKCNNLSIPTDAFSNLYYLRDLSIEGFKLVKSMLIHLPFSTSLYSLSLPTNCITDLFHVFHIFQNLIFIHNLDVGSNKIERVSLQHDLNISLPNITELVLEKNPLILIQQNALARFGIHLLNLGFTKLNLEDILNAGVENLKSLSLTSACRRAINKTHTLCSIAQRFQLKSLSAPVNRFSGIYTKDFLGCSSLEFLNLNHNHIHIVDPDLLYTLPKLKELHLSYSLLHMNLCPLSYQDNFTSSVEALYFIGNRITVLKNKQFFCMTKLTDLLLARNGIEHIEESAFWGLNDLRVLDLRNNRLTSLQISSLSGLSNLMELYLQNNVMESMQRYSLKWQTKLRLVKIGFVSVSVSFELFPNTETLDIQTTGKYITVFMNETAASSLKSLSVNGSHVELDIKCGHQFFSTLRELKVINNNGLISCSHYGYQLEHFENLENIQYHFSGAPLTRNVNFSNIANLRSLEVENLATALDPNVPPNDLFHKLHKLEVLKLFNCGFKYMTTALLKDMRSLRVLVMKNQMILAVDPGLQNTLSPLEFIYFIDVTFQCDCDNSWFVTWALEDKHTFVSGICSLFCLQLNKKFNLVNFSESSCRQEIDFMLFVITFTSLLLFIVLTMLCNIFNSDIIQLFYVFQIWLKKLRGKTNNPIAYEYDAFVSYCSRDQGWVVNYLVPNLEEKGRNTIKLCLHNRDFLVGKDIVDNIMDSIYKSRKTICLISYNYLQSDWCSLEMRMATYKLLAEKNDDLILVFLESISGYHLSAYHRLARIVRKKTYIDWPQEENEQAEFWERLRMTVLETKED Xt 21 frog Xenopus tropicalis MAILLVALTFVVLLIPGLTSYGFRNCIQSSVIINSYNCIARGLTDVKSAVGDLPSDVWYLNISYNNIQTLHQGSFGHMPFLRTLRLNHNQLQRLDPGAFENLTMLEKLHLSSNKISNLSKEVFCGLQNVSWLFLDDNLLSSIHPEAFSHLTNLQNLNLSMNNLHNFEKVVQSIHPLQKLNTLMLCSNQISSLNHTHRLPSTLRWLFLCKNQLATLDCQQDFFLNISWLDLSYNNIATSSLQTMDLRKVIYLNVAFNGNFDILIFIKNPTVPINRIDYSGLNLNNDSKLKTMCRYLKGFNINTLYLSGNKIKTLNRGTLTDCPLNKTLDLSRNRLKGLGCLEFMSKTNVENLIVEHNLLKELINCSKKSHFPRLRHISFRYNRIWIVKGNAFHFAPNLQTLYLNINNIVFLERYSFSGLGKLRELRLDNNLITDLYENSFANLTELRILNLRNNRVSVIFSKVFYNLGKLTTLDLGGNKITQLKNQSFYGLRSLSKLYLDGNQIKEISRYVFSHVESTLLVLDLKSNHLRYNTTRETYSPFLTLSKLYDLKLQAQQPYGLTAIPQGFFKGLKSLKALYLAQNRISSLSSDAFNELGQLTYLSLAEDCNGIQRLPPGIFKNLKNLQILDLENICLQYMRMEVFSSLTNLKRLLLTKNALTHINIKVFENMTQLKYLDLRKCPLSCTCNNAELQMWFKKGPVQIVLPYNLTCPANENSYFHDFDTHVCDMEIKIKLFCSSFTSILLFIIIPIVYSKFYWMIKYNYFLFVAWLHERWKSEKELYKYDAFVSYNTHDEEWVYKIMLPVLETSALRLCLHHRDFQLGRDIIDNIVDSIHNSRKTICVVSRSYLQSEWCSLEMQLASYKLFDEMRDVLVLILLDNIPDRELSTYHRMRKLMLKKTYITWPTEPEAQQLFWAKVQEAVSGKRPSEGHQGIKIVKW Xt 22 frog Xenopus tropicalis Sc1833 MGWLMLQFKMFSLFNCLVLFHLVTRGVSFAIKGCEVHRQYNLKVLCYNRDLTKVPAQLPELSFMLDLSHNIIKTINRTDFQNLTVLQNLNLSNNRIQYMENGAFGKLVALQLLNLTKNRIGSLSSRTFEGLQNLSTLLLDNNNIVTLEPNTFLHLYNLKTISLSYNCFYKLKTLNPAFQIGTLREINIANCSIQTFSTEDIVNVSASLRSVDASRNPFSVISFPMSILENLTNLDISLTQRPILWYVKEPCFLRGLKKLNIKENNIKPPAIIGIIKNLSCSSLEELNLSYLNLTDSDQLIQELCLRHPKVQTLKLTGNQYTEFREDTFQNCTSVKVLDLSHNRLHSAPGSTFHHLASIRELSLANNSLTAIPDNFSFITSLQKLNLSYNHVKEVNLNDSFSNLKELDLSGNKMTFFLSSGLGNWNLQDLNLRENYLLDISASFASSLPTLQRLTISKNKLSSLSTNTFQNVTFLKHLNLADNQIEVIDPGAFSGLDKLRTLIIGSNKITRNTLHNMTFQGLGSLLELQLFGNYLNYDSSNYLDIVPFLPLKSLKMITLNSQGHNGMQNLPINFFEGLLALERIHAGNLALSSIDSRTFSYTPQLRELDISENPIKILDPFLFRNVPHLTELHISKTRMESLDFLILSNLTHLKLLRAVDSQLNSFTSQQGAALPSLRFLDLRNNPLTCICDNQWFIDWVHNDTKTQVLHFYEYTCAYPPVARNSKLSTFNLSSCRLDYSFIFFLTSTLFITTFIISATVWNFWRWHVIYAYYITLAFLYNRRWQGKKQKCKYDAFISYNFHDEKWVFRQLVPNLEGRYNWRLCLHHRDFEPGKAIVDNIVDSIYSSRKTICIISRHYLESEWCSKEIQLASFRLFEEHTDVLILLFLEQIPDHHLSPYHQIRKVIKKKTYLIWPQERNATSIFWYRVSQALQTEEREEDEKCLLMy short name TLR Digit Species common name Species scientific name Accession # Length (AA) Notes FASTA AeTLRa yellow fever mosquito Aedes aegypti AAM97775 1124 AeTLRb yellow fever mosquito Aedes aegypti AAM97774 1007 AeTLRc yellow fever mosquito Aedes aegypti AAM97776 1076 AgTLR mosquito Anopheles gambiae AAL37901 AgTLRb ENSANGG00000015554 mosquito Anopheles gambiae XP_309195 964 AgTLRc ENSANGG00000006772 mosquito Anopheles gambiae XP_320221 845 AgTLRd ENSANGG00000006734 mosquito Anopheles gambiae XP_320172 788 AgTLRe ENSANGG00000006280 mosquito Anopheles gambiae XP_309461 1173 AgTLRf ENSANGG00000006278 mosquito Anopheles gambiae XP_309458 1168 AgSARM (was AgTLRg) ENSANGG00000011022 mosquito Anopheles gambiae XP_315931 744 Sterile alpha - TIR protein (motifs include ARM and SAM) AgTLRh ENSANGG00000015552 mosquito Anopheles gambiae XP_309194 1005 AgTLRi ENSANGG00000014747 mosquito Anopheles gambiae XP_307829 155 partial AgTLRj ENSANGG00000017045 mosquito Anopheles gambiae XP_309087 424 partial AgTLRk ENSANGG00000013260 mosquito Anopheles gambiae XP_314167 410 partial AgTLRl ENSANGG00000014400 mosquito Anopheles gambiae XP_311355 945 AgTLRm ENSANGG00000012039 mosquito Anopheles gambiae XP_308786 817 AgTLRn ENSANGG00000014148 mosquito Anopheles gambiae XP_311384 998 beeTLR1 honey bee Apis mellifera XP_396158 1068 beeTLRb LOC410235 honey bee Apis mellifera XP_393717 1291 beeTLRc Trex; LOC410231 honey bee Apis mellifera XP_393713 1248 beeTLR6 LOC410229 honey bee Apis mellifera XP_393712 1201 beeTLRd LOC410902 honey bee Apis mellifera XP_394378 1370 swormTLR silkworm Bombyx mori BAB85498 1295 cowTLR1 1 cow Bos taurus AAT48486 172 cowTLR2 2 cow Bos taurus AAT48487 cowTLR3 3 cow Bos taurus AAM91032 154 partial cowTLR4 4 cow Bos taurus NP_776623 cowTLR5 5 cow Bos taurus AAT48489 173 partial cowTLR6 6 cow Bos taurus NP_001001159 cowTLR9 9 cow Bos taurus NP_898904 cowTLR10 10 cow Bos taurus AAT48490 100 partial lancelet lancelet Branchiostoma floridae AAM18891 940 CbTLR worm Caenorhabditis briggsae CAE74340 1215 Celeg GeneID: 171635 worm Caenorhabditis elegans NP_490733 1221 dogTLR2 2 dog Canis familiaris NP_001005264 dogTLR4 4 dog Canis familiaris NP_001002950 636 dogTLR9 9 dog Canis familiaris NP_001002998 goldfish 22 goldfish Carassius auratus AAO53555 165 cfish Ci TLR7 sea squirt Ciona intestinalis AAP91723 933 no TIR domain hamTLR2 2 hamster Cricetulus griseus Q9R1F8 hamTLR4 4 hamster Cricetulus griseus Q9WV82 hamTLR6 6 hamster Cricetulus griseus AAN40691 389 partial zebTLR2 2 zebrafish Danio rerio NP_997977 788 zebTLR18 1 zebrafish Danio rerio AAQ91316 165 partial zebTLR19 not sure (on chr22; one of two tandem genes; best gene model not clear ortholog of any other TLR) zebrafish Danio rerio AAQ91317 103 partial zebTLR21 21 zebrafish Danio rerio AAQ91320 149 partial zebTLR22 22 zebrafish Danio rerio AAQ91321 198 partial zebTLR20a not sure (on chr5; best gene model not clear ortholog of any other TLR) zebrafish Danio rerio AAQ91318 174 partial zebTLR20f not sure (chr9; one of two tandem genes; best gene model not clear ortholog of any other TLR) zebrafish Danio rerio AAQ91319 175 partial zebTLR4b 4 zebrafish Danio rerio NP_997978 817 dTLR8 fruit fly Drosophila melaogaster AAF86224 dTLR7 fruit fly Drosophila melaogaster AAF86225 dTLR6 fruit fly Drosophila melaogaster AAF86226 18wheel 18w fruit fly Drosophila melaogaster NP_476814 1385 dTLR4 fruit fly Drosophila melaogaster AAF86228 dTLR3 MstProx fruit fly Drosophila melaogaster AAF86229 dTLR1 Tl fruit fly Drosophila melaogaster P08953 dTLR5 Tehao fruit fly Drosophila melaogaster NP_477438 795 dTLR9 fruit fly Drosophila melaogaster NP_649214 900 DyTLR fly Drosophila yakuba AAQ65064 1026 horTLR2 2 horse Equus caballus AAR08196 horTLR4 4 horse Equus caballus Q9MYW3 843 horTLR4_2 4 horse Equus caballus AAU95608 724 catTLR1 1 cat Felis catus AAU12171 234 partial catTLR2 2 cat Felis catus AAU12172 259 partial catTLR3 3 cat Felis catus AAU12173 232 partial catTLR4 4 cat Felis catus P58727 833 catTLR5 5 cat Felis catus AAU12174 217 partial catTLR6 6 cat Felis catus AAU12175 133 partial catTLR7 7 cat Felis catus AAU12176 255 partial catTLR8 8 cat Felis catus AAU12177 217 partial catTLR9 9 cat Felis catus AAN15751 gorTLR4 4 gorilla Gorilla gorilla AAM18617 hTLR1 1 human Homo sapiens NP_003254 hTLR2 2 human Homo sapiens AAC34133 784 hTLR3 3 human Homo sapiens O15455 hTLR4_C 4 human Homo sapiens NP_003257 799 hTLR4_D 4 human Homo sapiens NP_612567 639 hTLR4_B 4 human Homo sapiens NP_612566 782 hTLR5 5 human Homo sapiens NP_003259 hTLR6 6 human Homo sapiens NP_006059 hTLR7 7 human Homo sapiens AAQ88659 hTLR8_2 8 human Homo sapiens NP_619542 1041 hTLR8_1 8 human Homo sapiens NP_057694 1059 hTLR9_B 9 human Homo sapiens NP_619633 975 hTLR10 10 human Homo sapiens AAQ88667 811 hTLR11 11 human Homo sapiens AL138837 pseudogene; The sequence of the human pseudogene for TLR11 was acquired by TBLASTN search of human clones in Genbank with the mouse TLR11 sequence described by Zhang et al. (2004). The pseudogene hTLR11 is contained on clone RP1-149P10 (AL138837); a hypothetical protein sequence was created using mTLR11 as an alignment template. cfishTLR3 3 catfish ictalurus punctatus AAU95562 677 partial macTLR2 2 macaque Macaca fascicularis Q95M53 mTLR1 1 mouse Mus musculus AAG35062 mTLR2 2 mouse Mus musculus NP_036035 >gi|31981333|ref|NP_036035.2| toll-like receptor 2 [Mus musculus] MLRALWLFWILVAITVLFSKRCSAQESLSCDASGVCDGRSRSFTSIPSGLTAAMKSLDLSFNKITYIGHGDLRACANLQVLILKSSRINTIEGDAFYSLGSLEHLDLSDNHLSSLSSSWFGPLSSLKYLNLMGNPYQTLGVTSLFPNLTNLQTLRIGNVETFSEIRRIDFAGLTSLNELEIKALSLRNYQSQSLKSIRDIHHLTLHLSESAFLLEIFADILSSVRYLELRDTNLARFQFSPLPVDEVSSPMKKLAFRGSVLTDESFNELLKLLRYILELSEVEFDDCTLNGLGDFNPSESDVVSELGKVETVTIRRLHIPQFYLFYDLSTVYSLLEKVKRITVENSKVFLVPCSFSQHLKSLEFLDLSENLMVEEYLKNSACKGAWPPLQTLVLSQNHLRSMQKTGEILLTLKNLTSLDISRNTFHPMPDSCQWPEKMRFLNLSSTGIRVVKTCIPQTLEVLDVSNNNLDSFSLFLPRLQELYISRNKLKTLPDASLFPVLLVMKIRENAVSTFSKDQLGSFPKLETLEAGDNHFVCSCELLSFTMETPALAQILVDWPDSYLCDSPPRLHGHRLQDARPSVLECHQAALVSGVCCALLLLILLVGALCHHFHGLWYLRMMWAWLQAKRKPKKAPCRDVCYDAFVSYSEQDSHWVENLMVQQLENSDPPFKLCLHKRDFVPGKWIIDNIIDSIEKSHKTVFVLSENFVRSEWCKYELDFSHFRLFDENNDAAILVLLEPIERKAIPQRFCKLRKIMNTKTYLEWPLDEGQQEVFWVNLRTAIKS mTLR3 3 mouse Mus musculus NP_569054 >gi|31543872|ref|NP_569054.2| toll-like receptor 3 [Mus musculus] MKGCSSYLMYSFGGLLSLWILLVSSTNQCTVRYNVADCSHLKLTHIPDDLPSNITVLNLTHNQLRRLPPTNFTRYSQLAILDAGFNSISKLEPELCQILPLLKVLNLQHNELSQISDQTFVFCTNLTELDLMSNSIHKIKSNPFKNQKNLIKLDLSHNGLSSTKLGTGVQLENLQELLLAKNKILALRSEELEFLGNSSLRKLDLSSNPLKEFSPGCFQTIGKLFALLLNNAQLNPHLTEKLCWELSNTSIQNLSLANNQLLATSESTFSGLKWTNLTQLDLSYNNLHDVGNGSFSYLPSLRYLSLEYNNIQRLSPRSFYGLSNLRYLSLKRAFTKQSVSLASHPNIDDFSFQWLKYLEYLNMDDNNIPSTKSNTFTGLVSLKYLSLSKTFTSLQTLTNETFVSLAHSPLLTLNLTKNHISKIANGTFSWLGQLRILDLGLNEIEQKLSGQEWRGLRNIFEIYLSYNKYLQLSTSSFALVPSLQRLMLRRVALKNVDISPSPFRPLRNLTILDLSNNNIANINEDLLEGLENLEILDFQHNNLARLWKRANPGGPVNFLKGLSHLHILNLESNGLDEIPVGVFKNLFELKSINLGLNNLNKLEPFIFDDQTSLRSLNLQKNLITSVEKDVFGPPFQNLNSLDMRFNPFDCTCESISWFVNWINQTHTNISELSTHYLCNTPHHYYGFPLKLFDTSSCKDSAPFELLFIISTSMLLVFILVVLLIHIEGWRISFYWNVSVHRILGFKEIDTQAEQFEYTAYIIHAHKDRDWVWEHFSPMEEQDQSLKFCLEERDFEAGVLGLEAIVNSIKRSRKIIFVITHHLLKDPLCRRFKVHHAVQQAIEQNLDSIILIFLQNIPDYKLNHALCLRRGMFKSHCILNWPVQKERINAFHHKLQVALGSRNSA mTLR4 4 mouse Mus musculus AAH29856 835 mTLR5 5 mouse Mus musculus Q9JLF7 859 mTLR5_2 5 mouse Mus musculus BAC29603 853 mTLR6 6 mouse Mus musculus NP_035734 mTLR8 8 mouse Mus musculus P58682 mTLR9 9 mouse Mus musculus NP_112455 mTLR11 11 mouse Mus musculus NP_991388 >gi|45429992|ref|NP_991388.1| toll-like receptor 11 [Mus musculus] MPRMERHQFCSVLLILILLTLVSLTLTGWAWTIPDCIIADSLLFPNLSYYIPFCTSAPGLHLLASCSNVKNLNQTLKRVPRNTEVLCLQGMVPTLPAKAFIRFHSLQLLRLQLRTTSVTSRTFQGLDQLQYLFFDHHAPCCLSLFLSPNCFESLRSLSSLSFQGYCLTYSQSIYLPTSLRHLTLRNSCLTKFQDLQRLFPDLLLSTSSTPNIKPGAPFLETLDLSYNLQLKQAGVRDLYGLTLHSLILDGTPLKALDLTDSGLLHLHFLSLVGTGIEKVPASLTGYSELRALDLGKNQIQNILENGEIPGYKALEFLSLHDNHLQTLPTRFLHTLPQLQKLNLSMNKLGPILELPEGLFSTNLKVLDLSYNQLCDVPHGALSLLSQLQELWLSGNNISSLSNESLQGLRQLRTLDLSWNQIKVLKPGWLSHLPALTTLNLLGTYLEYILGIQLQGPKMLRHLQLGSYPILDIYPPWPPTLLSLEIQAESCIQFMIHSGQPFLFLENLTLETSILLLKPDNITIHFPSLRRLTLRGYSFIFSTSQLQRFFPQQLPLLEHFFIWCENSYAVDLYLFGMPRLRVLELGYLNFFYESSTMKLEMLLKEVPQLQVLALSHLNLRNLSVSSFKSLQDLKLLLFNSERALEMNSNLQEFIPQMPQYVYFSDVTFTCQCEASWLESWATRAPNTFVYGLEKSICIANASDYSKTLLFSFLATNCPHGTEFWGFLTSFILLLLLIILPLISCPKWSWLHHLWTLFHTCWWKLCGHRLRGQFNYDVFISYCEEDQAWVLEELVPVLEKAPPEGEGLRLCLPARDFGIGNDRMESMIASMGKSRATLCVLTGQALASPWCNLELRLATYHLVARPGTTHLLLLFLEPLDRQRLHSYHRLSRWLQKEDYFDLSQGKVEWNSFCEQLKRRLSKAGQERD mTLR12 12 mouse Mus musculus NP_991392 906 mTLR13 13 mouse Mus musculus NP_991389 model may extend too far 5' at N-terminus; use later start methionine >gi|45429999|ref|NP_991389.1| toll-like receptor 13 [Mus musculus] MSGLYRILVQLEQSPYVKTVPLNMRRDFFFLVVTWMPKTVKMNGSSFVPSLQLLLMLVGFSLPPVAETYGFNKCTQYEFDIHHVLCIRKKITNLTEAISDIPRYTTHLNLTHNEIQVLPPWSFTNLSALVDLRLEWNSIWKIDEGAFRGLENLTLLNLVENKIQSVNNSFEGLSSLKTLLLSHNQITHIHKDAFTPLIKLKYLSLSRNNISDFSGILEAVQHLPCLERLDLTNNSIMYLDHSPRSLVSLTHLSFEGNKLRELNFSALSLPNLTNLSASRNGNKVIQNVYLKTLPQLKSLNLSGTVIKLENLSAKHLQNLRAMDLSNWELRHGHLDMKTVCHLLGNLPKLETLVFQKNVTNAEGIKQLAKCTRLLFLDLGQNSDLIYLNDSEFNALPSLQKLNLNKCQLSFINNRTWSSLQNLTSLDLSHNKFKSFPDFAFSPLKHLEFLSLSRNPITELNNLAFSGLFALKELNLAACWIVTIDRYSFTQFPNLEVLDLGDNNIRTLNHGTFRPLKKLQSLILSHNCLKILEPNSFSGLTNLRSLDLMYNSLSYFHEHLFSGLEKLLILKLGFNKITYETTRTLQYPPFIKLKSLKQLNLEGQRHGIQVVPSNFFQGLGSLQELLLGKNPSVFLDHHQFDPLINLTKLDISGTKDGDRSLYLNASLFQNLKRLKILRLENNNLESLVPDMFSSLQSLQVFSLRFNNLKVINQSHLKNLKSLMFFDVYGNKLQCTCDNLWFKNWSMNTEEVHIPFLRSYPCQQPGSQSLLIDFDDAMCNFDLGKVYFLCSFSMVLSTMVFSWFSTKMIASLWYGLYICRAWYLTKWHKTEKKFLYDAFVSFSATDEAWVYKELVPALEQGSQTTFKLCLHQRDFEPGIDIFENIQNAINTSRKTLCVVSNHYLHSEWCRLEVQLASMKMFYEHKDVIILIFLEEIPNYKLSSYHRLRKLINKQTFITWPDSVHQQPLFWARIRNALGKETVEKENTHLIVVE troutTLR22 22 trout Oncorhynchus mykiss CAF31506 troutTLR5 S5 trout Oncorhynchus mykiss BAC65467 664 no TIR domain troutTLR5m 5 trout Oncorhynchus mykiss BAD38860 879 rabbitTLR2 2 rabbit Oryctolagus cuniculus AAM50059 rabbitTLR4 4 rabbit Oryctolagus cuniculus AAM50060 chimpTLR4 4 chimpanzee Pan paniscus Q9TTN0 (identical to AAF05320) 839 may have some gene model problems as does not align as well as expected to human ortholog chimpTLR1 1 chimpanzee Pan troglodytes XP_517148.1 760 may have some gene model problems as does not align as well as expected to human ortholog chimpTLR1 2 chimpanzee Pan troglodytes XP_526707 1235 may have some gene model problems as does not align as well as expected to human ortholog chimpTLR10 10 chimpanzee Pan troglodytes XP_517147 499 may have some gene model problems as does not align as well as expected to human ortholog babTLR4 4 baboon Papio anubis Q9TSP2 halTLR2 2 halibut Paralichthys olivaceus BAD01044 818 "nearly identical to BAD01046 Identities = 796/818 (97%), Positives = 796/818 (97%), Gaps = 20/818 (2%)" halTLR2_2 2 halibut Paralichthys olivaceus BAD01046 798 halTLR22 22 halibut Paralichthys olivaceus BAD01045 961 halTLR22_2 22 halibut Paralichthys olivaceus BAD01047 961 orangTLR4 4 orangutan Pongo pygmaeus Q8SPE9 ratTLR1 1 rat Rattus norvegicus XP_223421 ratTLR2 2 rat Rattus norvegicus NP_942064 >gi|38454274|ref|NP_942064.1| toll-like receptor 2; toll-like receptor 2 variant 2; toll-like receptor 2 variant 1 [Rattus norvegicus] MLQALWLFWILMAVIGLSREGHSAQASLSCDAAGVCDGSSRSFTSIPSGLTANTKKLDLSFNKITYIGHGDLRACVNLRVLTLESSGINTIEGDAFYSLGSLEHLDLSNNHLSSLSSSWFRPLSSLKYLNLMGNPYRTLGETSLFSNLTNLQTLRVGNVDTFSEIRRIDFAGLTSLNELEIQVLSLGNYESRSLQSIRDIYHLTLHLSESAFLLGIFADILSSVRYLELRDTNLARFQFSELSVDEINSPMKKLAFRNADLTDKSFNELLKLLRYILELMEVEFDHCTLNGVGNFNPSESDVVRELGKVETVTIRSLHIPQFYLFYDLSTVYSLLEKVKRITVENSKVFLVPCSFSQHLKSLEFLDLSENLMVEEYLKNSACEGGWPSLQSLVLSQNHLRSIRKTAEILLTLKNLTALDISKNSFQPMPDSCQWPGKMRFLNLSSTGIQAVKTCIPQTLEVLDVSNNNLDSFSLFLPRLQELYISRNKLKTLPEASLFPVLQVMKIRENAISTFSKDQLGSFPKLETLEAGDNHFICSCELLSFILERPALVHVLVDWPDSYLCDSPPRLHGQRLQDARPSVLECHQAALVSGVCCALLLLILLLGALCYHFHGLWYLRMMWAWLRAKRKPKKAPCRDLCYDAFVSYSEQDSYWVENLMVQQLENSDPPFKLCLHKRDFVPGKWIIDNIIDSIEKSHKTVFVLSENFVRSEWCKYELDFSHFRLFDENNDAAILVLLEPIEKKAIPQRFCKLRKIMNTKTYLEWPLDEGQREVFWANLRTAIKS ratTLR3 3 rat Rattus norvegicus NP_942086 >gi|38454316|ref|NP_942086.1| toll-like receptor 3 [Rattus norvegicus] MKGRSSYLIYSFGGLLSLWILVVSSTNQCTVRYNVADCSHLKLTHIPDDLPSNITVLNLTHNQLRGLPPANFTRYSQLALLDAGFNSISKLEPELCQILPLLKVLNLQHNELSQISDQTFAFCTNLTELHLMSNSIRKIKSNPFKNQKSLIKLDLSHNGLSSTKLGTWVQLENLQELLLAKNKIFALRNEELDFLGNSSLQKLDLSSNPLKEFSPGCFHAIGKLFVLLLNNAQLNLDLTEKLCWELSNTSIQNLSLANNQLLATSNSTFSGLKQTNLTSLDLSYNSLRDVGNDAFSWLPHLKYLSLEYNNIQRLTPHSFRGLSNLRYLSLKRAFTKQSVALASHPNIDDFSFQWLKCLEHLNMDDNTIPGIKSNTFTGLVSLKYLSLSKTFTGLQTLTNETFVSLTHSPLLTLNLTKNHISKIASGTFSWLGQLRILDLGLNEIEQELTGQEWRGLGNIFEIYLSYNKYLQLTSKSFTLVPSLQRLMLRRVALKSVDISPSPFRPLYNLTILDLSNNNIANLNEDLLEGLENLEILDFQHNNLARLWKHANPGGPVNFLKGLSHLHILNLESNGLDEIPVKVFKNLFELKSINLGLNNLNTLLPSIFDDQTSLRSLNLQKNLITSVEKSVFGPAFHNLNSLDMSFNPFDCTCESIAWFVTWLNQTHTNIPELSTHYLCNTPQRYHGLPVKLFDTSSCKDSAPFQLLFIINTSTLLTFILAVLLIHFEGWRISFYWNVSVHRILGFKEIDAQGEQFEYTAYIIHAQKDRDWVWEHFSPMEEQDQSLKFCLEERDFEAGVLGLEAIVNSIKRSRKIIFVITHHLLKDPLCRRFKVHHAVQQAIEQNLDSIILIFLQNIPDYKLNHALCLRRGMFKSHCILNWPIQKERINAFHHKLQVALGSRNSAH ratTLR4 4 rat Rattus norvegicus NP_062051 ratTLR5 5 rat Rattus norvegicus XP_223016 ratTLR6 6 rat Rattus norvegicus NP_997487 ratTLR7 7 rat Rattus norvegicus XP_228909 ratTLR9 9 rat Rattus norvegicus NP_937764 ratTLR10 10 rat Rattus norvegicus XP_223422 ratTLR13 13 rat Rattus norvegicus XP_228540 >gi|34881297|ref|XP_228540.2| similar to toll-like receptor [Rattus norvegicus] MCGSSVVPSLQLLLMLIGLSLLSLAETYGFNKCTQYEFDIHHVFCIRKKITNLTEAISDIPRYTTHLNLTNNYIQVLPPWSFTNLSALVDLRLEWNLIWKIDEGAFRGLENLTLLNLVENKIQSVNNSFEGLSNLETLLLSHNQITHIHKDAFTPLVKLKYLSLSRNRISNFSGILEAVQHLPCLEHLDLINNSIMYLDHSPRSLVSLTHLSFEGNNLTELNFSTLSLPNLTNLSASQNGHGVIQDVYLKTLPQLQSLNLSGTVVKLEMLSAKHLQNVRVMDLSNRELKHGHLNMKIVCYLLRNLPMLEILFFHKNATNAEGIKQLAKCTRLLFLDLGQNSDLVHLNDSEFNALPSLQRLNLNKCQLSFISNKTWSSLQNLTILDLSHNKFKSFPDFAFSPLKRLEFLSLSRNPITELNNLAFSGLFSLKELNLAACWIVTIDRYSFTQFPNLEVLDLGDNNIRTLNHGTFQPLKKLHTLILSHNRLEIMESNAFSGLTGLRYLDLMYNSLSYFHKHHFMGLEKLLVLKLGFNKITYETTRTLQYPPFMKLKSLKQLNLEGQKHGIQVVPRNFFQGLSSLQELLLGKNPSVFLDHHQFDPLINLTKLDISGTKDGDRSLYLNSSLFQNLKRLKVLRLENNNLESLVPGMFSSLQNLQVFSLRFNNLKVINQSHLENLKSLMFFDVYGNKLQCTCDNLWFKNWSMNTEEVHIPFLRSYPCQQPNSQSLLIDFDDAMCNFDLGKVYFLCSFSVVLSTMVFSWFSAKMIASLWYGLYICRAWYLTKWHKTEKKFLYDAFVSFSATDEAWVYKELVPALEEGSQTTFKLCLHQRDFEPGIDIFENIQNAINASRKTLCVVSNHYLHSEWCRLEVQLASMKMFYEHKDVIILIFLEEIPNYKLSSYHRLRKLINRQTFITWPDSAHQQPLFWARIRNALGNETVEKENTHLIVVE pigTLR1 1 pig Sus scrofa CAE47753 partial pigTLR2 2 pig Sus scrofa NP_998926 >gi|47523322|ref|NP_998926.1| toll-like receptor 2 [Sus scrofa] MPCALWTAWVLGIVISLSKEGAPHQASSLSCDPAGVCDGRSRSLSSIPSGLTAAVKSLDLSNNRIAYVGSSDLRKCVNLRALRLGANSIHTVEEDSFSSLGSLEHLDLSYNHLSNLSSSWFKSLSTLKFLNLLGNPYKTLGEAPLFSHLPNLRILKIGNNDTFPEIQAKDFQGLTFLQELEIGASHLQRYAPKSLRSIQNISHLILHMRRPALLPKIFVDLLSSLEYLELRNTDFSTFNFSDVSINEHCTVMKKFTFRKAEITDASFTEIVKLLNYVSGALEVEFDDCTLNGRGDLSTSALDTIKSLGNVETLTVRRLHIPQFFLFYDLRSIYSLTGAVKRITIENSKVFLVPCSLSQHLKSLEYLDLSENLMSEEYLKNSACEHAWPFLHTLILRQNHLKSLEKTGEVLVTLKNLTNLDISKNNFDSMPETCQWPEKMKYLNLSSTRIHSLTHCLPQTLEVLDISNNNLNSFSLSLPQLKELYISRNKLKTLPDASFLPMLSVLRISRNTINTFSKEQLDSFQKLKTLEAGGNNFICSCDFLSFTQGQQALAQVLSDWPENYLCDSPSHVRGQRVQDTRLSLTECHRVAVVSVVCCALFLLLLLTGALCHHFHGLWCMKMMWAWLQAKRKPRKAPRRDVCYDAFVSYSEQDSYWVENLMVQELEHFQPPFKLCLHKRDFIPGKWIIDNIIDSIEKSQKTIFVLSENFVKSEWCKYELDFSHFRLFDENDDTAILILLEPIEKKTIPQRFCKLRKIMNTRTYLEWPADETQREGFWLNLRAAIKS pigTLR4 4 pig Sus scrofa BAD36843 >gi|51465802|dbj|BAD36843.1| toll-like receptor 4 [Sus scrofa] MIPRIRLAVATIPAMAFLSCLRSESWDPCVQVVPNISYQCMELNFYKIPDNIPTSVKILDLSFNYLSHLDSNSFSSFPELQVLDLSRCEIQTIDDDAYQGLNYLSTLILTGNPIQSLALGAFSGLPSLQKLVAVETNLASLEDFPIGHLKTLNELNVAHNHIHSFKLPEYFSNLPNLEHLDLSKNKIENIYHEHLQVLHQVPLHNLSLDLSLNPLNFIEPGAFNKIRLNGLTLRSNFNSSDVMKTCIQGLAGSKVNQLVLGEFKNERNLESFDKSVLEELCNLTLEQFRIAHFGEFPDDVSDLFNCLANASVISLLSLNLHGLEALPNDFRWQHLEVVNCKLQQFPALKFNSLKKFVFKDNKHMHTFTEINLPNLQFLDLSGNHLSFKGCCSHNEFGTTKLKHLDLSFNEIITMKSNFMGLEQLEYLDFQHSSLKQANDFSIFLSLRNLHYLDISYTNIHVVFRGIFAGLVSLQTLKMAGNSFQNNLLPDVFTDLTNLILLDLSKCQLEQVSQRAFHSLPRLQVLNMSHNRLLFLDTLPYKPLHSLRILDCSYNLIVASKEQELQHLPRSLAFLNLTKNDFSCACEHQTFLQWVKDQKQLLVGAEQMVCTQPLEMQDLPVLSFRNATCQISEAVISASVLTFLLVSVAGILVYKFYFHLLLFVGCKKYGRGESTYDAFVIYSSQDEDWVRNELVKNLEEGVPPFHLCLHYRDFIPGVAIAANIIQEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLRSHAGIIFIVLQKLEKSLLRQQVELYRLLSRNTYLEWEDSVLGRHIFWRRLKKALLDGKPWSPEGTEDSESNQHDTTAFT pigTLR6 6 pig Sus scrofa NP_998925 >gi|47523320|ref|NP_998925.1| toll-like receptor 6 [Sus scrofa] MTKDKKPTVISLHSVYVMTLVWGTLIQFSEESEFVVDKSKIGLTRVPKDLPPQTKVLDVSQNFITELHLSDISFLSQLTVLRLSQNRMQCLDISVFKFNQDLEYLDLSHNQLQTILCHPITSLKHLDLSFNDFEALPICKEFGNLTQLNFLGLSATKLQQLDLLPIAHLHLSCILLDLERYYMKENEKESLQILNTEKLHLVFHPNSFFSVQVNISVKSVGCLQLANIKLGDDNCQVFITFLLELTQGPTLLNFTLNHVETTWKCLVGIFQFLWPKPVEYLSIYNLTIVESIDEEDFIYYETTLKGVKIEHITKRVFIFSQTALYRVFSDMNIRMLTIADTHFIHMLCPQVPSTFNFLNFTQNVFTDSVFQNCKTLARLETLILQKNKLEDLFKISLMTKDMLSLEILDVSSNSLEYDRHGENCTWVGSIVVLNLSSNILTDSVFRCLPPRIKVLDLHSNRIRSIPKDVAHLEALQELNVASNSLAHLPGCGSFSSLSILSIDYNSISNPSADFFQSCQKIRSLKAGNNPFQCTCELRDFIQSLGQVSSDVVESWPDSYECEYPESYKGTLLKDFRVSELSCNTALLIVTIGVTGLALALTMTGLCVYFDLPWYLRMLCQWTQTRRRARNVPLEELQRTLQFHAFISYSEHDSAWVKNELVPCLEKEGIKICLHERNFVPGKSIMENIINCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHNLFHEGSDNLILILLDPIPQNSIPGKYHKLKALMAQRTYLEWPKEKSKHGPFWANIRAAFNIKLKLVAEEDDVKT pigTLR8 8 pig Sus scrofa NP_999352 >gi|47523454|ref|NP_999352.1| Toll-like receptor 8 [Sus scrofa] MTLHFLLLTCLFLLIPDSCEFFTGANYSRSYPCDERKENGSVIAECTNRQLQEVPRRVGNYVTELDLSDNFIRRITNESFQGLQNLTKINLNHNAKLWPQSENGMTITDGAFLNLHHLRELLLEDNQLREIPTGLPESLRELSLIQNKIILLNTKNMFGLRKLESLYLGWNCYFTCNETFIIDEGAFENLTNLKVLSLSFNTLYRVPPKLPSSLTKLYLSNTKIRNINQEDFKGLENLRVLDLSGNCPRCFNAPFPCNPCPGDASIQIHPLAFRYLTALRYLNLSSTSLRRIPATWFENLHHLKVLHLEFNYLMDEIASGNFLAKLPSLEILDLSYNYEQKKYPQYINISHYFANLTSLQILHLRAYVFQELRKEDFQPLRNLLHLKFINLGINFIKQIDFTIFSEFSNLSIIYLSENRISPLVNNTGQKNGDRPSFQSHVLKPRSATPKFDPHSNFYHNTKPLIKPQCSRYGKALDLSLNSIFFIGPNQFEAFKDIACLNLSSNGNGQVLHGSEFSHLPGIKCLDLTNNRLDFDDDAAFSELPLLEVLDLSYNSHYFRIAGVTHRLGFIQNLPQLRVLNLSHNSIFTLTETYLKSTSLKELVFSGNRLDLLWNAQDDRYWQIFKNLSTLTHLDLSSNNLQHIPSEAFLNLPQTLTELYISDNRLNFFNWSLLQQFPNLTLLDLSGNELSFLTDSLSKFTTSLQTLILRQNRISYLPSGLLSEASSLTHLDLSSNQLKMVNISKLHAKTTTNLAILKLDRNPFDCTCDIRDFRKWMDENLRVTIPRLTDVICASPGDQRGRSIVSLELTTCVSDTIAAIICFFTFFVTSTVMLAALAHHWFYWDAWFIYHVCLAKVKGYRSLPTSQTFYDAYVSYDTKDASVTDWVMNELRFHLEESEGKNVLLCLEERDWDPGLAIIDNLMQSINQSKKTIFVLTKKYAKNWNFKTAFYLALQRLMDENMDVIVFILLEPVLQHSQYLRLRQRICKSSILQWPDNPKAEGLFWQSLKNVVLTENDSRYNSLYVNSIK pigTLR9 9 pig Sus scrofa NP_999123 Ucrab horseshoe crab Tachypleus tridentatus BAD12073 1058 fTLR21 21 fugu Takifugu rubripes BAC66138 793 fTLR23 23 fugu Takifugu rubripes AAW70378 fTLRS5 S5 fugu Takifugu rubripes AAW69378 fTLR9 9 fugu Takifugu rubripes AAW69377 fTLR8 8 fugu Takifugu rubripes AAW69376 fTLR7 7 fugu Takifugu rubripes AAW69375 fTLR5 5 fugu Takifugu rubripes AAW69374 fTLR3 3 fugu Takifugu rubripes AAW69373 fTLR22 22 fugu Takifugu rubripes AAW69372 fTLR21 21 fugu Takifugu rubripes AAW69371 fTLR2 2 fugu Takifugu rubripes AAW69370 fTLR14 14 fugu Takifugu rubripes AAW69369 fTLR1 1 fugu Takifugu rubripes AAW69368 tetTLR2 2 Tetraodon Tetraodon nigroviridis CAF90327 seems to have some small problems with frame in gene model >tetTLR2 CDASFSCNCSSAGLTRVPVVTGRALSLDLSSNLIAAVTAEDLRDHGRLRVLSLHRNRLVLIHPAAFDPLRDLEDLDLSNNQLTALEPSWFRQLEALRVLNLLHNPYSRLGPAPPFQNLLSLRRLKVGGPDLEELRTGDLAGVSPLEELSVQANGLRRYEAGALADIWPLGSVVLSLHRPFLEDQDLASSVLGDVSHPETALTLRDLNLTWAQSIRPLRAAARSRIRHLTFQNLSLSDVAVVELLVVLDGVPLTRLAMEDVTLKGQGRWERANWTDHRSIDEFLVRDMEVLDVYQFVSLGALGFLLQYPRKVSLVNAEVYVMPCLTSYLLRNLQYLDLSDNLLTDMTLTETLCDGRSPLRALRVLNVSGNALKSLSSTSRLLARFHRLSHVDLSRNVYGSMPGACSWPPSLRHLNLSRTRIRSVSRCLPAALEVLDLSHNDLRDLVLVLPALRELHLSGNKFLRLPAGCFFPSLHTLSIQANGLGQFGASDLRAYRRLRDLRAGGNSFVCTCDFVSFFRAAVAAPAVRLTDGEGSYVCDAPLHLRGALVSRVRLEPAQCHPVLVVSAGCGGALLVGAGVGVLLWRVHAFWYLRMTWAWLKAKRSSPAAARTRGAKVGEEPSATSCSWALGPGRTSSAPWSAAAGPSSCSPATSCAPSGAASSWTSPTSSSWTEPPRGGRQSSSSWSRCRTAQSPRRYCKLHRLLSSTTYLEWPQQEDKVEAF tetTLR22 22 Tetraodon Tetraodon nigroviridis CAG05452 647 tetTLR3 3 Tetraodon Tetraodon nigroviridis CAF96592 906 partial; seems to have some small problems with frame or retained introns in gene model; missing N-terminus >tetTLR3 SSCRVQGDSADCSHLSLDSIPPDLPGNLTSLDMSHNRLRGIPPEALRPYPGLLRLIVNYNSIAKLDGRLCETLPRLRTLNVAHNQLLTLREEDLNPCSGLTELNLSSNRLRLQGEPFSGLQNLKYLDVSLNKLQSARLGSRPQLPALVTLSLAHDTISVLRRDDFSFLNHSSFFRVLNLSSVLLKELEPGCLKPISGLSTVILDGTNTGTQVIAKLCSELSGTAISTLSLRNMKLVTLTNNTFVGLQKTNLSCLDLSRNGLGRIEKGSFLFLPRLQTLILEENNIKHLTSDTFQGLHSLKSLQLTKALVKGHTSANPVIDDFSFQPLKALESLVLQKTAIWKITPQTFTGLTSLMELDLSWSSCVSLKNITNQTFVSLAGSPLRKLNLTGTAITQISPGGFSALRNLTVLLLDSNFIRQTFSGRELEGLAQLEEMHMSLNYQKVNLSSASFVAVPSLRVLTLGKSLISTALNLDPSPFSPLVHLSYLDLSNNNIANIRRTLLKGLGRLKVLKLQHNNFARLWKNANPGGPVMFLQDAVKLRTLLMDSNGLDEIPAEALRGLTELQELSLGSNLLNSLRDSVFNDLTSLQALYLEKNMITTVRPEVFKTPMSNLGLLVMGRNPFDCTCESILWFVKWLNSTNTTSVPGLTEQYTCNTPLAYFNRSIMVFDPLSCKDSTPFQALFVLSSASVILLLVVALFVRFQGWRIQFYWNIMVNRTLGFSDAAVGEGRQFEYDAYVIHAEADGAWVERRLLPLENEKCKFCLEIRDSNPGMSQLESIVNNIRNSRKILFVVTETLLRDPWCRRFTARQALHQVIEASRDSVVLVFLQDVHDHRLSRTLFLRRGMLRSCCVLYWPVHKERVAAFHQKLLIALGMTNRLHD tetTLR5 5 Tetraodon Tetraodon nigroviridis CAF94909 838 tetTLR1 1 Tetraodon Tetraodon nigroviridis CAG06259 789 tetTLR8 8 Tetraodon Tetraodon nigroviridis CAG05899 has some retained introns in the gene model; incorrectly combines portions of TLR7 and TLR8 tetTLR9 9 Tetraodon Tetraodon nigroviridis CAG07333 1019 tetTLR21 21 Tetraodon Tetraodon nigroviridis CAF98054 349 partial tetTLR9384 23 Tetraodon Tetraodon nigroviridis CAF93842 939 tetTLR1b 1b Tetraodon Tetraodon nigroviridis CAF95159 455 has some errors and is missing the C-terminus due to a gap in the assembly; The gene model used for the gloobal vertebrate alignment and tree is the corrected Tetraodon TLR1b 592-residue N-terminus supplemented with the 176-residue Takifugu C-terminus. This hybrid gene model is only used to compute molecular distances and will have the effect of making the Tetraodon TLR1b appear to be slightly more closely related to the Takifugu sequence but should not affect any of the conclusions in this paper. frogTLR5 5 frog Xenopus laevis AAH84773 878 My short name TLR Numerical Deisgnation Species common name Species scientific name Scaffold # Length (AA) Notes Sequence Md 3 opossum Monodelphis domestica MERCLIHWSYFFLRILPFCMVCTQSVKNCVVRNEVADCSHQKLTQIPPDLPANITTLNLTHNQLKRLPPANLTRYGQLVILDGGFNSISKLEPELCQSLPLLKVLNLQHNELSQLSDKTFAFCLSLTELHLKSNPIQKISDNPLKNLKNLHLLDLSHIGLSSAKLGTQVQLENLQELLLTNNKIRMLKREDFDYLGNSSLRKLDLSSNHLIEFSPDCFRSIGKLYDLSLNNVQLGPELTEKLCLELSSTSVQSLNLSAIQLTKISNMTFRGLNQTNLTVLNLSHNGLTSIANDSFAWLSHLEWLVLENNNIDHLFSRSFYGLSNVKYLNLKRSFFKPKNSKISFPKIDDFSFQWLKCLEYLSMEDNSFSGITTNMFTGLTNLKSINLSSSFANLQILTNTTFSSLAYSPLLILNLTRNKISQIESGAFSWLGHLEVLDLGVNEISQELTGQEWKGLENIMEIYLSYNRYLILNSNSFASVPILKRLMLRRVDCKQLDVSPSPFHPLRNLTILDLSNNNIANINAEMLEGLDKLEILDLQHNNLARLWKHANPGGPVHFLKGLSHLRVLNLESNGFDEIPSDVFKGLFQLRAIYLGLNNLNLLPASLFDHQTSLKSLSLQKNLITSVEKGVFGPAFQNLTLLDMSFNPFDCTCESIAWFVSWLNKTHTHIEDLPSHYLCNTPPQYHGTPVMLFDISPCKDSAPFKMFFIINASFLCTLIFVVLLVHFQGWRISFYWNVTIHRALGFKEIERQQEQFDYAAYIIHAQEDSRWIWKYFSPMEEKDHSLRFCLEERDFEAGRPELEAIVHSIKRSRKIIFVVTQNLLKDPLCKRFKVHHAVQQAIEQNLDSIILIFLEDIPDYKLNHALCLRRGMFKSHCILHWPAQKERVHAFYQKLQVALGMRNRAH Md 6p opossum Monodelphis domestica "scaffold_13309:3,733,832-3,734,101" NA "pseudogene; 3733832-3734149 on scaffold; mostly a TIR domain with stop codons; orthologus region in humans and mice may be recombinogenic (e.g., is telomere-most on mouse chr5)" FVLS*TPGQV*ADVCRYLTVDAIICSPKLFHECSDNLILILLKPIPQYNIPSKYHKLKVLMQ*RTYLEWPKKKSEQALFWTNIRAAFNMKLTLVEEANDIE Md 2 opossum Monodelphis domestica MRQIRWSVWILCTIINFSEEDAPKQTSLSCDPAGGVCDGHSRSLDTIPSDLTEAVRQLDLSFNKISHIRELDLRNCVNLEALLLQSNRIRSIDPDSFQFLRNLKHLDLSSNSLSYLSPSWFNSLSSLRVLYLHKNPYQRLGQSPLFSHLPSLRVLKVGSYDRFSELQKQDFEGLRELEDLEIEAAYFQKYEPGSLKSIHKINHLALSIRKPNLLPDILVDLASSLQYLEFRKTNLGEFNFSMPPNTPSPLIEKIILREVIVTDKSFIDILKMFSYASELLEIVLEDCILNGLGLWEEDFISEIHHEVKVETIIIRRLRIGNFFLFRDLSPVYSLLQGIKRITLTSSKVFLVPCDLSKSLKSLEYFDLSDSLMSEGALENSACEGAWPSLHTLNLSQNKFESLKTMGELLLTVKNLTHLDISKNNLDSMPDSCQWPGKLKYLNISSTKTYTVTSCIPQTLEILDISNNQLSDFNLNLPHLKELYLSKNKLKTLPDAAHFPHLVVMNISQNTLYTFSKAQLESFQTTEILAAGGNNFICSCEFLSFVHHEQTLLVKVLTDWPGGYLCDAPFQVRGQRVQDVQLSFSECYRVELVAAICSSLFLLALLAGVLCYQFHGIWYMKMMWAWLQAKRKPRRNPDREICYDAFVSYSEGDSHWVENFMVQELENFDPPFRLCLHKRDFVPGKWIIDNIIDSIDKSHKTLFVLSESFVKSEWCKYELDFSHFRLFDENNDTAILILLEPIEKKTIPQRFCKLRKIMNTKTYLEWPRDEGLQEEFWFNLRAAIKS Md 4 opossum Monodelphis domestica MPAISACLISLLRHIHLLYHICMGSWVGRILSGNFPLFKSCLFYTPILLCRCDIQKIEDDTYEGLHNLSTLILTGNPIQSLGIRAFYGLPKLQKLVVVETNLMSLEDFPIGHIITLQELHLGHNSISSLQLPSYFASFSSMKHLDLHLNQIKNISDGDLEPVKLNPNLTLDLSENPIQYIHPGAFKGIHLSGLKLRSSFHNSTIMEACIKGMTGLKVGKLVLGNYKNDIQMTSFESSILDGLCEVDIGEFRMVQPSQFPSDGNGVFKCLVNVSVLFLVNTDIDQLTNLPIFPKLFSLSLTDCNFDIMPDLPSISLPSLKELKVTHHKDLTTLSDLALPNLQILDLSKNSLNVLSCCSDKTFNTPNLKYLNLSYNAHISLSKNFMGLENLESLDLQHTILKDHDKYPAFYSLINLRYLDISYTNTHVKFKNIFTGMSNLKHLKMAGSSFQDNILHDIFKNLTKLVSLNISYCQLERVSQETMSPLHQLQVLDLSHNKLQTFDPFICMPLLNLQVLNCSSNSITALNGENLQELSRTLISIDLSDNPFDCVCDHQIFFQWVKEHTHLLNRSKPMTCQTPSHMKDISVQLFDDSTCHMKKTVIAVSLLGIIVILLVLALVYKFYFHLMLLAGCKNIGGGESIYDAFVIYSSQDEDWVRKELVKNLEEGVPSFQLCLHYRDFIPGVAIAANIIQEGFHKSRKVIVVISEHFIQSRWCKFEYEIAQTWQFLSSQAGIIFIILQKVEKSLLRQQMELYRLLNRNTYLEWEDTNLGRHVFWRRLRKALLDGRTKNPKGAAEEEFSQPVSPT Md 5 opossum Monodelphis domestica MGHLLAFLLGLVFKATSVYGIPSCSADGQLAFYRFCNLTQVPQVPNTTTKLLLSFNYIRVVNATSFPLLDQLQFLELGTQNIPLTIEREAFRNLPNLLVLDIGNTKIQFLHTDAFQGLFNLVQLQLYYCHLSDSILKDGYFRNLSSLAILDLSRNEIENLQLHPSFGNLESLKSIDLSLNHISLICKRDLEVLQGKRFSLFNLASNNLYSKVSVNWKECMNPFKNMSFEILDVSSNGWTVDIVRDFCHAIQGTRISSLLLNYHIMGGGFGFHNLKEPDQDTFAALGMSSVIKMDISHGFIFSLNFHLFETLRELKVMNLSHNKVNKIANGAFYGLDNLQILNLSYNLLGELYQSDFAGLSKVAYIDLQRNHIGIIEKQTFKHLKNLQTLDLRDNAIKTVYFLPSVHTAFLSGNKLVHIEENINITAGFLDLAENRLANLNDLYILLQIPDLKFLILNKNRFSFCNQQYGPSKNHTLEQLYLSENMLQLIWEAGKCWDVFKRLSHLKILFLNNNYLNFLPPDVFSDLTALQILSLDGNKLISLSPGVLPENLRVLSLSQNHLLSPDPTVFASLSYLDITHNKYICECEARNFILWLNQTKVNMLGSPEDVYCTYPDSFSGVSLYSISTEGCDEEEALQFIHFSLFIFFTTTLTVFLTAVVTFTRFRGCCFLLWRKMFLTLALEYHPQGVKEDQHKYDAYLCFSSKDFEWVQNAFLNHLDSQYSPKNRFNLCFEERDFLPGEDHINNIRDAICNSKKTICIVTRHFLKDGWCIEAFNFAQSRYFSDLKDVLIMVVAGSLSQYQLMKYPPIRVFVQRQPYLKWPEDLQDVGWFLNKLSQRILNKKEEKKKSNNIPLQTVATIS Md 6 opossum Monodelphis domestica MCTTKLWFIPDPPIINTFHFVLIFVLILGSVIQHSSQNEFIGNYSNSHLSHVPHHLSPKTTVLDLSLNNITEIQIEDFKLLPKLRVLILSHNRIQHLNISVFKFNQDLEYLDLSHNNLWDISCHLLMNLIHLDLSFNEFEFLPICEEFSNLSQLDFLGLSAKRIQKSDLLPVSHLNLSNILLDLERFGGAKDKLETLPVLNTKKLQIIFPPNRAFFMQLNISVNNLRSLQITNINLNNDKCSVFTDFLSKVIHNSKSLNLTLYHIEDTWKCFVEILQFLWHKPIEYLYIYNLTLVGKIGFELFTYNETLLKGLKIEFINIKVYIFLQSNIYNIFSNMNINMLTITDSRMLHMSCPFKPSPFQYLNFANNLFPDTIFPDCKNLSLLQTLILQKNKLTHLSKIAGMTEKMKSLKHLDLSQNSISYDEEKKNCSWSESLLVLNLSSNELTESVFRCLPPSITVLDLYRNKIKSIPKNISNLESLQELNIAFNFLVDLPGCSTFSSLSVLIIQHNSVSHPSAHFFNSCQNIKSLQAEDNPFLCTCELREFSKNMATLSSQVVSGWPHSYKCAFPDNYKGTHLKDFHLSPLSCNIVLLLITIVIVVLVFVIVTTFFCVYFDLPWYLRMIFQWARMRRRARNIPLDELEKEVQFHAFISYSELDSPWVKHELLPNLEQEEIRICLHERNFVPGKSIVENIINCIEKSHKSIFVLSPNFIQSEWCHYELYFAHHKLFHERSDNLILILLEPIPQYNIPAKYHKLKALMARRTYLEWPKEKGKQALFWANIRAAFNRKLTLVEEANDVEII Md 7 opossum Monodelphis domestica FHIYLFVHRICPLLASFLLLLFQIFHVRGLYRSFLILFHLFILYKLPRARWFPKTLPCNVTQNIMEASVMVNCTEKHLTEIPNGIPSNTTNLTLTINHIPKISPNSFAGLKNLVEIDFRCNCVPVRLGPKDRICTKRPNIDSGSFRNLTKLKSLYLDANQLSEIPLDLPSSLQLLSLEANHIFSITRENLTDLVNLEILYLGQNCYFRNPCNDSFSIEKDAFQSLRNLTLLSLKANNLTAVPTVLPSSLTELYLHNNNIQRFKKDDFHNLYQLQILDLSGNCPRCFNVPFPCIPCPNNSPLVIHGGAFDSLSELKILRLHSNSLQHIPKSWFKNTKKLEELDLSQNFLAKEIGEAKFLNSLVNLKDLDLSFNYEPQVYRAYLNLSNTFASLKNLKILRLKGYVFKELQSTHLFYLKNLSQLEVLDLGTNFIKIADLSVFKNFPALKNIDLSVNKISPRESSQNGFCSWARTSTEFQTSFENIHYFRYDEFARRCKFKSKEEPFLPLLRNDCESYGELDLSRNNLFFVKPSDFEDLSFLKCLNLSGNSISQTLNGSEFQPLAKLKYLDFSNNKLDLLHSTAFQELQELEVLDISGNSHYFQSEGITHMLNFTKNLQVLKKLMMNGNDISTSTSTEMESESLKILEFRGNHLDVLWRDGDNRYLGFFRNLIHLEVLDISQNSLSFLPTGVFEGLPPNLKTLLLSKNQIKSFNWNKLSCLQNLETLDLSHNLLSRVPEVLSNCSRSLKKLILSYNQIHQLTKNFLQDAFQLRYLDLSSNKLRVIQKSSFPENVLNQLDVLLLHGNRFFCNCDAVWLVWWINQTEVTIPYLATEVTCAGPGVHKGQSLIKLNLYTCELDLINSILYMTSMFIILCLMVIPVASHLYFWDMWYSYHFCKAKLKGYQRLISPQFCYDAFIVYDTSDPKVVEWVFKELVENIESQGDKQFNLCLEERDWIPGKPVLENLSHSIQLSRKTVFVMTNAYVKSGNFKTAFYLSHQRLMDEKVDVIILIFLEKAFQRSKYLQLRKRLCKSSVLEWPTNPQAHPYFWQCLKNAIATDNDTVYSKVFKETL Md 8 opossum Monodelphis domestica MIPQYLSFTCLCLLVACSPEVLDHIVNSRGYPCSFRKNNSFVFADCQGCRLHSVPMIFKNVTEVDLSFNSIMEITNKSFAGLLNLTKINLNSNVDSQVENRANKRRMNISDGAFFNLKNLRDLLLEENLLQKIPVGLPPSLTTLSLVLNNISSISKDNMLGLTHLSSLYLGWNCFYGNGCERNVSIEDGAFEHLTNLTVLSLSFNNLLHVPTKLPPSLKELYLSNNKIKNISQDDLKGLENLRVLDLSGNCPRCFNSPFPCVPCENGASIQIHPDAFQNLANLTYLNLSSTSLRSIPVSWFSNMPKLKVLHLEFNYLVQEIATGGFLTKLRNLEILDLSYNYLKNQYPFYITLSSNFSKLDSLKVLHIRGYVFQELRKKDFQSLMKLPKLQIINLGVNFISRINLTLFKDFRNLTVIYLSENRISPPVTGKYLSFAHHAIHPRSVDTDNEPLARGIIDPHKNFYHYSRPLVKPECSSYGKALDLSLNSMFFINSLQFQSFNDVKCLNLSFNGNAQVLNGSEFLSMPHIKYLDLTHNQLDFDSDRAFQELQELEVLDLSHNEHYFQIAGVTHRLGFIQNLAHLKVLNLSQNDIFTLTEHQLESDSLEELVFKGNRLDIMWMEEDNRYIKIFTNLSNLTRLDLSFNRLHTIPTEAFHNLPQSLVELRLNNNHLRVFNWTSLQYFHNLTLLDLRCNSLFTIKPDLYESSVQTLLLGKNIISHLPDGLFSKAKNLYHLDLSYNLIKMVNKSTFHMKTSNNLKILNLRGNPFDCVCEMGDFRKWIDENPNVTIPRLVDVICSTPGDQTGKSIMELELTTCVSDLTAIISFFFSFIITVTTMVMATFHHFFYWDIWYIYHLCSAKIKGYKSLSTSQTFYDAFVAYDTKDTCVTDWVINGLRFQLEENEDKKVFLCLEERDWDPGIAIIDNLIQSINQSKKTIFVLTKKYAKNWNFKTAFYLALQRLMDENMDVIIFILLEPVLQHSQYLRLRRRICKSSVLKWPDNPRAEDLFWQSLKNVVLTDNDTRYNNLYVKFIK Md 9 opossum Monodelphis domestica MSLLALARALAHTSFPQFLPCELRNSSVVDCDRRSLGSVPPFFEATPSALANVTTLLLRHNHINHLQPAHFVRLKGLQKLLLRWNCAPTILTVLRQSCHMVIEQGTFLVLHHLKELDLSGNSITFIPELPPSLTSLVISYTMILRLDSDTFSGLCGLRSLYMDGNCYYKNPCEREVEVVPRALENLHHLENLSLKYDNLTSVPQGLPASLRMLLISSNRIVSLSPQDFVGLPALQVLDVSRNCRRCDHAHNPCQECPPGFPKVHPDTFSHLGALEGLVLKDNSLSRLDPRWFRNLVNLTVLDLSENFLSEDITVTRAFQNLTKLKKLNLSFNYHKKVSFAYLHLAPSFQNLTALQVLDMSGIFFRSLTQATLQPLLGLPHFQKLLLPMNFISKADLGIFGLFHSLQFVDLSDNKVTGGSNAGRVNGALLEEEGASQDPLPTLGVNRAPEVIAETLLEEEGASQDHPLTSELFMPNCGPPNFTLDLSQNNLVTVQQEIFVNLSALKCLRLSSNSISQAVNGSQFSPLTNLWLLDLSHNKLDLYYSSSFTELPRLRALDLSYNSQSFKAHGIGHNLTFVSRLRSLRYLSLAHNQINTRISHSLSSPSLIALDFSGNELSRMWAEGDLYLRFFQNLRTLVRLDLSQNKLRSLPAQALDNLPKSLRLLWAKDNHITFFNWSSLSSLPHLEVLDLSRNLLGHTSSLATGRLPNGSRLHTLRLSRNSIRFIALGFFALATELKVVDLSGNALKTVVRGWFGGLGPSLKKLDIRANPLSCGCDATFLDFLLEIQRAVPGLSTEVVCGSPSPLSGKSIFLEDLHSCQDPVLACSCFALSLLGTLLTLALATLQRLFGWDLWYIFHLGLSWLPWRAWQKRKAPAQAYDYDAFVVFDKAQEAVADWVYNELRVRLEEAKGRGKGWLRFRLCLEDRDWLPGKSLIENLWDSVYKSRKTLFVLSPRRDPLLGQPVSGLLRATFHLAQQRLLEDKQDVVVLVILNRAVGRSRYVRLRQRLCRQTVLFWPHQPSGQDSFWAQLCTALATNNRSFYDRNFCRGP Md 10 opossum Monodelphis domestica "scaffold_15136:1,800,754-1,802,991" MGIIRNIYILYSIDLSVLCGALLLPEMNELTTNCSQEYFKKVLMGMSLKITTMDLSNTFTCQPQNLDLSPFSKLKVLILSHNKIQHLDISIFQFNKELEYLDLSYNSLRNISCYPLLGLKHLDLSFNDFNNIPICQEFGSMSQLEFLGLSGAQIQKSHLQKVAHLHLNTVFLGLKHLSSYEEGSLSLLNTERLRIVFPEIADYRFILRDGIHTSKILEMANINMNQFTNHDNQKNPLLEKPKGSKTSHLLLSNVYGPWQEFLQALQFVWHSSIQQLQIQNFTLGAQSEFKTKIFDYSNTSMKVIKVEHVSIKIYSFPQDRIYLFFTQMGTENLTISGAGMPHIIFPDYPSKFQHLNFTNNALTDELFRKTLLLPHLKTLVLQRNKLETLSTVSSFAINTSLIHLDLSQNLLQHTDGNHCHWPETLTTMNLSSNKFIDSIFKCIPKSIQVLDLHNNDIRTIPREIENLKALQELNIASNSLTDLPGCRNFQRLSALNVEMNSIISPSLDFFQSCQEVQSLKAGDNPFRCNCDLRNFINLEKKSQGLMIGWPDAYTCEYPLELKGIHLENVDLPALSCNTPLLIAVILIIGLLWTVVIAILCIRFDLPWYLRMISQWTQNRHRVRNVPIEELKRTIQFHAFISYSEMDSLWVKSELIPNLEKEDRSISICLHERHFVPGKSIIENIINCIEKCYKSIFVLSPNFVQSEWCHYELYFAHHKVFHEGSNNLILILLEPIHSTAFPSSIIS Md 13 opossum Monodelphis domestica MGPKARGMPLKWLWFIVLEFSLLSLVEMYGFRHCTQYKFNIHHVLCVRKNITNLKESIHDLPEYVTHLNLTHNQIQTVPSRSFVNLSNLVDLRLEWNFIWDLGPEAFQGLKNLTLLNLVENKLQSINSSFEGLSSLKTLLLSHNQISWIQENAFVPLINLQYLNLSRNAITTFSNVLAAVQHLPCLEVLDLTYNTIASLDCNPTTLVSLTKLILMKNKLVDLDFSTLSLPNLTTLDVSQNALQNVHLDTLPQVKRLNLSQTCLEVEKLDAKHLQNLIELDLSGITPLPNTKHVNLSAVCHLLQNLPRIETLFFQKNGIDSENIKHLANCTMLVSLDLSHNKDLVHLCNSEFSDMPSLERLDLNSCMLSLVSNMTWDSLQNLTVLDLSRNRLKTFPDFAFAPLRRLQSLSLSRNPITELNNLSFYRLHELKELNLAGCWIVAIDSYSFSQFLSLENLNLRENNLRTLKKNTFLFLKNLQVLTLSYNRLATIEKSAFSGLPKLYKLDLAYNILSDFHPGMFLGLEGLEVLDLSFNKITYETLKSLQPPPFKDLQTLKRLNLEGQINGIQVVPINFFQGLGSLQELLLGKNSKVFLDHLQLDQLPNLTRLDISGTKAGNRGLYLNISLFQKLKQLKSLQLENNNLDSLAPEMFFGLEGLQIFSLRFNNLKIINQNLLQNLKSLMYFDVYGNKLECTCDNGWFKNWSVSTPTVHIPYLGSFQCQQPNTQSLLVGFDTSICNFDTGKICFFCSFSLVLATMVCSWFGTKMISSMRYGIYMFKSLYLAKWHRTEREFVYDAFVSFNAADEEWVYKELVPALEKVGQPTFKLCLHHRDFELGVDIFENIQNAINTSRKTLCIVSNNYLQSEWCRLEVQLASLQMFYDYQDVIILIFLEEIPNYRLSSYHRLRKLVKRQTFITWPEDFQERPLFWARIRNALGNKTVREENARLILTDPLGD Md 1L opossum Monodelphis domestica "scaffold_15136:1,828,857-1,831,265" MCTTKLWFIPDPPIINTFHFVLIFVLILGSVIQHSSQNEFIGNYSNSHLSHVPHHLSPKTTVLDLSLNNITEIQIEDFKLLPKLRVLILSHNRIQHLNISVFKFNQDLEYLDLSHNNLWDISCHLLMNLIHLDLSFNEFEFLPICEEFSNLSQLDFLGLSAKRIQKSDLLPVSHLNLSNILLDLERFGGAKDKLETLPVLNTKKLQIIFPPNRAFFMQLNISVNNLRSLQITNINLNNDKCSVFTDFLSKVIHNSKSLNLTLYHIEDTWKCFVEILQFLWHKPIEYLYIYNLTLVGKIGFELFTYNETLLKGLKIEFINIKVYIFLQSNIYNIFSNMNINMLTITDSRMLHMSCPFKPSPFQYLNFANNLFPDTIFPDCKNLSLLQTLILQKNKLTHLSKIAGMTEKMKSLKHLDLSQNSISYDEEKKNCSWSESLLVLNLSSNELTESVFRCLPPSITVLDLYRNKIKSIPKNISNLESLQELNIAFNFLVDLPGCSTFSSLSVLIIQHNSVSHPSAHFFNSCQNIKSLQAEDNPFLCTCELREFSKNMATLSSQVVSGWPHSYKCAFPDNYKGTHLKDFHLSPLSCNIVLLLITIVIVVLVFVIVTTFFCVYFDLPWYLRMIFQWARMRRRARNIPLDELEKEVQFHAFISYSELDSPWVKHELLPNLEQEEIRICLHERNFVPGKSIVENIINCIEKSHKSIFVLSPNFIQSEWCHYELYFAHHKLFHERSDNLILILLEPIPQYNIPAKYHKLKALMARRTYLEWPKEKGKQALFWANIRAAFNRKLTLVEEANDVEIIMy short name TLR Digit Species common name Species scientific name Accession # Length (AA) Notes FASTA chimpTLR6 6 chimpanzee Pan troglodytes Nov. 2003 (panTro1) assembly >ENSPTRT00000029822.1 MTKDKEPIVKSFHFVCLMIIIVGTRIHFSDGNEFAVDKSKRGLIHVPKDLPLKTKVLDMSQNYIAELQVSDMSFLSELKVLRLSHNRIQLLDLSVFKFNQEEYLDLSHNQLQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNAKTLHLFHPTSLFAIQVNISVNTLGCLQLTNIKLNDDNCQVFIKFLSELTRGPTLLNFTLNHIETTWKCLVRVFQFLWPKPVEYLNIYNLTIIESIHEEEFTYSKTTLKALKIEHITNKVFLFSQTALYTVFSEMNIMMLTISDTPFIHMLCPHAPSTFKFLNFTQNVFTDSIFEKCSTLVKLETLILQKNGLKDLFKVGLMTKDMPSLEILDVSWNSLESGRHKENCTWVESIVVLNLSSNMLTDSVFRCLPPRIKVLDLHSNKIKSVPKQVIKLKALQELNVAFNSLTDLPGCGSFSSLSVLIIDHNSVSHPSADFFQSCQKMRSIKAGDNPFQCTCELRQFVKSIDQVSSEVLEGWPDSYKCDYPESYRGTPLKDFHMSELSCNITLLIITIGATMLVLAVTVTSLCIYLDLPWYLRMVCQWTQTRRRARNIPLEELQRNLQFHAFISYSEHDSAWVKTELVPYLEKEDIQICLHERNFVPGKSIVENIINCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHNLFHEGSNNLILILLEPIPQNSIPNKYHKLKALMMQRTYLQWPKEKSKRGLFWANIRAAFNMKLTLVTENNDVKS*My short name TLR Digit Species common name Species scientific name TLR Numerical Deisgnation Scaffold # Length (AA) Notes Sequence m 10 mouse Mus musculus "chr5:63,529,591-63,531,910" NA pseudogene ATGAGACGCAGCAGCGGCATCCATACACTTTATAACATCCTGATGTCAACAGAAGCCTGGGCTCCAAGGCCGACAGGTGAAAGGGGACTGATCTCCAACTTCTCTAACATGGCTTTAAGGAAGGTTCCCCGAGATGTGACTCCAGCCACAACCACACTGGATTTATCCTACAACCTCCTCTATCAATTGCAGAGCTCAGATTTCCACTCTTTTTCCAAACTGCATTTTCTGATCCTGTGCCACAAGATCCAAGAGCTGGACACCAGGAACAAGATCCAAGAGCTGGACACCAGGAACAAGATCCAACAGCTGGACACCAGGAACAAGATCCAACAGCTGGACACCAGGAACAAGATCCAACAGCTGGACACCAGGAACAAGATCCAACAGCTGGACACCAGGAACAAGATCCAACAGCTGGACACCAGGAACAAGATCCAACAGCTGGACACCAGGATCTTTGACCTTAACAAGGAGTTAAGCTATTTAGACTTGTCTTACAACAGACTAAAGTCCATCACTTTGTCTTCCATGGCAGATCTCATTTAGATCTTTCTTTTAATGACTTTGATATTCTGCCTGCCTGTGAGAAGACAGGCAACATTGCCGTATCTGGAAACCCTAGCTTTGAGCGGGGCAAAAATACAAAGCTCAGATCTCCAGAAAATTGCTCGTGTGCATCTCAGCACTGTGTTGTGAGGGCTGCGTACTCTGTCTCTCTATGAAAAACAGACTGCCCATCCTAAACACGACAGCGCTTCATGTCGTTTTACCAATGAACACAAATTTCTGGGTGCTTTTGCGTGATGGAATGAAGACTTCAAAAATAGTAGAAATGCCAAATATAGGTGGCAAGAGACATTTTCTAAGTTATGAGACTCCGAGAACTCTTTCTGTGGAGAACACCAAGGCGTGCACTCTGATACTCCATAAAGTTGACTTGCTCTGGGACGACCTTCTCCACATTTCCCAGTTTGTGTAGCGGACATCAGTGGAATGCTTCCAGATTCAGGGCCTGACTTTTGGAAGGATGGTTAATCGGGACCCATTCATTTGACTTCTCAAATACTGTATTGAAGGCTATAATCTTCATACATCTCAGGATCTCTTTTATTCCCCAGGATAGAATCTACTTGTTTTTCACCCAAATGGATTTAGAAAACCTGACGATATCTGGTGCACAAATGCCACATCTGCTCTTCCCTAGTCACCCCCAAAGTTTCCAGCATTTAAATTTTGCCAATAACATnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnCCGCCAATAACATCTTAACAGACGACCTGTTTAAAAACCCTATCTAGCTGCCTTATTGGAAACCTCTCATTTTGAGGGGCAACAAACTGGAGACTCTTTCTCTGGTGAGTCTCTTTGCCTGTGAATTAAGAGATTTCAATTGGCTTGAAAAACATCCCAAGGGCCTGATGGCTGGGTAGCCAGATTCATATGCCTGTGAATATCCTTTGAGTCTGAAGGCGACTCCATTAAACGATGTTTCTCTTTCCCAATTAGCTTGCAACACAACTTGGCTGATGGTCACCATTGTGCTGGTTGTGCTGATTCTGGGTTTGGGTGTAGCATTCTGCATGCTTTACTTTCACGGATGCTGGTATCTCAGGATGCTGGGCCAGTGCATACGGACCCAGCATAGCGTTAGGAAGACAATTCAAGAGGAGTGTAAGAGAAGTGTACAGTTCCACACCTTTATCTCCTATGCTGCACAAGATACAGCCTGGGTGAAGAACAAACTGATTCCCAATTTAGAAACAGAAGATGGCTCTGTCCTGCTTTGTCTTCCGGGGAGAAACTTTGACCCTGACAGGAGCAGTGCTGAAAATATAATAAGCTGCACTGAGGAAAGCTATAAGTCCATCTTCATGCTGTCTCCCAACTTTGTTCGGAATAGGTGGTTCCTTGCCACCCAGAGTCCCCTTGTCCCTTCCTTGGAGACCTTGGCAGAACCCAGAGAAGTCATGGTGGGGTGGGGCAGAGGGGGAGCTGGAAACTAATACACTGTGGCTTTGACTTTTGGGGAAGTGAAACAGACGTTGTAGGAGATGCTGCAAACCTTGAGTGAAATTGTCCACACGAGACAACTCCCTTCCAAGATGAACCGTTTAGCCTTACACTCACCAGGATTCAGCTATTTCATGGC h 12 human Homo sapiens 12 AL138837 NA pseudogene; hypothetical translation used to represent the hTLR11 pseudogene in phylogenetic analyses (derived from Genbank AL138837) GWTISNSLVTEGSRLSMVSRFFLICLLDSSLPFLTTCLSVINLVRALETVLQNVEGLCQSGSTSALPQDAFSRFPGLKVLGLNLHLTQLLPGALWGLGQLHYVFHSSHRGSINLPTADAFGDLRSLQDLAFLGSCLDGSLGVRLPPSLWLSIRCNFLQNVGVLADIFPDLVHGPSSGDAWALDMLDLSFNSRLKLASPGAFQVLKLGTLNLDHTKMKADALVGRGLQRLDALVTLTDMAELPARMVAHFELQELNLGINRTRHIALEGLASCHSLKSSGLRSNGLIELPRGFLAAMPXXXXXXXXXXXXXSAMLCMNETGFVSGLWALDLSKNRLCTLSPVIFSCLPHLRELLLQGNQLVCLKDQVFQGLQRLQTLNLGNNPLVTLGEGWLAPLPTLTTQNLVGTHMVLSPTWGFRGPESLHSLRIQFPFGPAGVAFSLLTRLTSLELHAVSGMKHWRLSPNVFPVLQILTLKGWGLQLETQNISKIFPALHQLSLLGSRLEPLCSQDTSSFFLWQLPKLKSLKDWGNRHSPRPYCITGLPSLQELKLQALQSQACPCPVRLEELVGELPRLDMLQLSQTGLETLSAAAFGGLGSLQVLVLDREKDFMLDDSLQEHSPRMPQYIYILTSSLACQCANACVGPWLQSPRTYMHIVSQQLCHSEAGGHSKNLFFPFLWSHCPKTLGLELFFAQLCPAASAGLLALPKEARNSWILLKALLRVWFQSLRSQKGKGKRFLYDVFVSHCRQDQGWMVQELLPALEDCPPAGRGLPLCLHEWDFEPGKDVADNAADSMVGSWVTLCVLSHQALHTPCXXXXXXXXXXXXXAVPHPPGLLLVFLEPILRHLPCCHRLAWLLRRDYCMWPKEEERKNDFWAWLGSRL (see also worksheets for individual species) Scaffold TLR Evalue TIR Evalue strongylocentrotus Supertig52464 4.00E-79 1.00E-27 Supertig59191 7.00E-77 4 Supertig47565 2.00E-67 1.00E-60 Supertig4912 3.00E-66 2.00E-26 Supertig81728 6.00E-65 3.00E-62 Supertig62631 4.00E-64 4.00E-74 Supertig39917 1.00E-63 2.00E-64 Supertig37 5.00E-62 1.00E-34 Supertig1616 3.00E-61 2.00E-36 Supertig98427 4.00E-61 3.00E-75 Supertig82079 4.00E-60 8.00E-37 Supertig74609 7.00E-60 6.00E-62 Supertig62371 2.00E-59 3.00E-74 Supertig78534 2.00E-59 1.00E-62 Supertig49981 3.00E-59 8.00E-37 Supertig756 4.00E-59 2.00E-82 Supertig92537 2.00E-58 1.00E-61 Supertig78739 4.00E-58 1.00E-71 Supertig29949 1.00E-57 4.00E-77 Supertig17746 2.00E-57 3.00E-55 Supertig59350 3.00E-57 5.00E-41 Supertig57541 2.00E-56 7.00E-55 Supertig65101 9.00E-56 2.00E-70 Supertig4531 2.00E-55 5.00E-72 Supertig394 2.00E-55 1.00E-49 Supertig84974 2.00E-55 3.00E-43 Supertig8715 4.00E-55 2.00E-79 Supertig619 4.00E-55 1.00E-67 Supertig100620 4.00E-55 2.00E-50 Supertig14920 7.00E-55 7.00E-62 Supertig81164 1.00E-54 4.00E-69 Supertig101935 4.00E-54 2.00E-78 Supertig76207 2.00E-53 8.00E-69 Supertig55391 2.00E-53 4.00E-39 Supertig22188 3.00E-53 3.00E-64 Supertig79314 3.00E-53 1.00E-62 Supertig24 9.00E-53 6.00E-69 Supertig2998 1.00E-52 4.00E-76 Supertig81761 2.00E-52 2.00E-78 Supertig80807 5.00E-52 1.00E-67 Supertig37773 6.00E-52 6.00E-70 Supertig57544 6.00E-52 2.00E-54 Supertig62453 8.00E-52 2.00E-79 Supertig814 8.00E-52 5.00E-55 Supertig27179 9.00E-52 2.00E-59 Supertig63355 1.00E-51 9.00E-84 Supertig27183 2.00E-51 3.00E-38 Supertig63449 3.00E-51 3.00E-77 Supertig1756 5.00E-51 1.00E-29 Supertig1739 7.00E-51 8.00E-56 Supertig28471 9.00E-51 9.00E-71 Supertig1165 2.00E-50 9.00E-46 Supertig90230 2.00E-50 4.00E-26 Supertig91021 4.00E-50 1.00E-70 Supertig58418 4.00E-50 6.00E-70 Supertig757 6.00E-50 6.00E-54 Supertig54340 1.00E-49 4.00E-71 Supertig98607 1.00E-49 1.00E-55 Supertig69233 3.00E-49 2.00E-71 Supertig10630 3.00E-49 3.00E-56 Supertig50917 4.00E-49 9.00E-76 Supertig80577 4.00E-49 6.00E-41 Supertig31146 1.00E-48 4.00E-77 Supertig9133 2.00E-48 5.00E-71 Supertig46407 3.00E-48 5.00E-68 Supertig75772 4.00E-48 4.00E-69 Supertig60751 4.00E-48 5.00E-68 Supertig78527 6.00E-48 9.00E-70 Supertig16562 7.00E-48 10000 Supertig387 8.00E-48 2.00E-70 Supertig16690 1.00E-47 1.00E-71 Supertig52627 1.00E-47 5.00E-71 Supertig34370 1.00E-47 4.00E-49 Supertig97443 2.00E-47 2.00E-71 Supertig70494 2.00E-47 3.00E-43 Supertig9518 2.00E-47 10000 Supertig99548 3.00E-47 2.00E-67 Supertig50416 4.00E-47 3.00E-80 Supertig105347 5.00E-47 2.00E-70 Supertig95081 7.00E-47 2.00E-52 Supertig37218 7.00E-47 2.00E-49 Supertig25814 9.00E-47 2.00E-72 Supertig71474 1.00E-46 5.00E-69 Supertig46576 2.00E-46 1.00E-05 Supertig104262 2.00E-46 0.002 Supertig15548 3.00E-46 8.00E-45 Supertig16829 3.00E-46 10000 Supertig91079 4.00E-46 2.00E-70 Supertig84849 4.00E-46 6.00E-43 Supertig1247 5.00E-46 8.00E-69 Supertig657 7.00E-46 2.00E-70 Supertig77711 8.00E-46 5.00E-50 Supertig98602 8.00E-46 10000 Supertig26468 1.00E-45 9.00E-68 Supertig67485 1.00E-45 10000 Supertig19857 2.00E-45 1.00E-70 Supertig1493 2.00E-45 8.00E-69 Supertig26229 2.00E-45 1.00E-45 Supertig702 3.00E-45 9.00E-71 Supertig9195 3.00E-45 2.00E-70 Supertig40893 4.00E-45 5.00E-69 Supertig34931 4.00E-45 5.00E-44 Supertig1727 4.00E-45 5.00E-44 Supertig1058 5.00E-45 2.00E-47 Supertig61223 1.00E-44 6.00E-70 Supertig104823 1.00E-44 1.00E-55 Supertig304 1.00E-44 2.00E-42 Supertig37771 1.00E-44 10000 Supertig23113 2.00E-44 1.00E-70 Supertig48352 3.00E-44 2.00E-72 Supertig70896 6.00E-44 2.00E-85 Supertig16274 8.00E-44 5.00E-15 Supertig27474 8.00E-44 10000 Supertig83701 9.00E-44 9.00E-54 Supertig1017 1.00E-43 10000 Supertig82317 2.00E-43 3.00E-47 Supertig52178 3.00E-43 1.00E-71 Supertig811 3.00E-43 4.00E-71 Supertig22050 3.00E-43 1.00E-66 Supertig22758 3.00E-43 3.00E-51 Supertig80755 4.00E-43 8.00E-51 Supertig38068 6.00E-43 10000 Supertig1109 7.00E-43 9.00E-70 Supertig93965 7.00E-43 4.00E-69 Supertig12992 7.00E-43 2.00E-66 Supertig100179 1.00E-42 8.00E-69 Supertig45664 2.00E-42 5.00E-48 Supertig38277 3.00E-42 6.00E-72 Supertig51914 4.00E-42 1.00E-50 Supertig77863 2.00E-41 10000 Supertig12047 5.00E-41 7.00E-36 Supertig64238 5.00E-41 10000 Supertig42233 6.00E-41 9.00E-79 Supertig1811 3.00E-40 10000 Supertig1770 7.00E-40 10000 Supertig63710 8.00E-40 6.00E-77 Supertig49985 9.00E-40 5.00E-50 Supertig46019 9.00E-40 1.00E-05 Supertig65488 1.00E-39 3.00E-70 Supertig47987 1.00E-39 4.00E-52 Supertig94143 3.00E-39 4.00E-31 Supertig28569 4.00E-39 10000 Supertig70304 6.00E-39 3.00E-43 Supertig52122 7.00E-39 10000 Supertig87604 6.00E-38 10000 Supertig48064 1.00E-37 9.00E-29 Supertig373 3.00E-37 1.00E-54 Supertig30517 7.00E-37 10000 Supertig19973 9.00E-37 4.00E-34 Supertig1555 2.00E-36 4.00E-56 Supertig7312 2.00E-36 5.00E-47 Supertig67503 2.00E-36 10000 Supertig36145 3.00E-36 9.00E-81 Supertig99560 3.00E-36 8.00E-32 Supertig408 4.00E-36 6.00E-35 Supertig67502 8.00E-36 10000 Supertig24695 2.00E-35 1.00E-68 Supertig46405 2.00E-35 3.00E-58 Supertig276 2.00E-35 3.00E-11 Supertig8770 2.00E-35 10000 Supertig59958 3.00E-35 5.00E-84 Supertig55559 3.00E-35 5.00E-50 Supertig67203 3.00E-35 10000 Supertig89505 3.00E-35 10000 Supertig10601 7.00E-35 2.00E-63 Supertig80441 2.00E-34 10000 Supertig17861 2.00E-34 10000 Supertig97432 3.00E-34 8.00E-25 Supertig961 3.00E-34 10000 Supertig61139 5.00E-34 4.00E-41 Supertig15524 2.00E-33 2.00E-66 Supertig35897 3.00E-33 10000 Supertig1185 5.00E-33 10000 Supertig84987 6.00E-33 10000 Supertig51631 8.00E-33 2.00E-51 Supertig102513 1.00E-32 10000 Supertig91430 2.00E-32 5.00E-32 Supertig512 2.00E-32 10000 Supertig96847 4.00E-32 5.00E-16 Supertig18687 7.00E-32 10000 Supertig42365 9.00E-32 1.00E-70 Supertig1871 2.00E-31 10000 Supertig24843 1.00E-30 10000 Supertig89724 2.00E-30 3.00E-17 Supertig38290 2.00E-30 10000 Supertig2589 3.00E-30 8.00E-50 Supertig20516 4.00E-30 10000 Supertig92955 5.00E-30 10000 Supertig82193 8.00E-30 10000 Supertig11170 8.00E-30 10000 Supertig54310 8.00E-30 10000 Supertig277 8.00E-30 10000 Supertig40595 1.00E-29 2.00E-19 Supertig9587 1.00E-29 10000 Supertig65467 2.00E-29 1.00E-55 Supertig59957 7.00E-29 3.00E-83 Supertig59956 1.00E-28 2.00E-81 Supertig75173 1.00E-28 6.00E-61 Supertig1461 1.00E-28 7.00E-47 Supertig1690 2.00E-28 10000 Supertig91248 3.00E-28 7.00E-18 Supertig39048 4.00E-28 1.00E-49 Supertig105471 6.00E-28 10000 Supertig728 7.00E-28 10000 Supertig67210 8.00E-28 10000 Supertig33734 1.00E-27 8.00E-72 Supertig32587 1.00E-27 8.00E-37 Supertig3135 1.00E-27 10000 Supertig1196 2.00E-27 10000 Supertig4 3.00E-27 10000 Supertig80183 4.00E-27 5.00E-71 Supertig89238 5.00E-27 6.00E-72 Supertig37860 5.00E-27 10000 Supertig19589 7.00E-27 5.00E-56 Supertig54379 7.00E-27 10000 Supertig12 9.00E-27 10000 Supertig35616 1.00E-26 1.00E-55 Supertig61617 1.00E-26 10000 Supertig58940 1.00E-26 10000 Supertig42408 1.00E-26 10000 Supertig1164 3.00E-26 1.00E-70 Supertig26236 7.00E-26 3.00E-38 Supertig98946 9.00E-26 10000 Supertig6873 1.00E-25 5.00E-71 Supertig69907 1.00E-25 5.00E-49 Supertig15455 1.00E-25 10000 Supertig41444 3.00E-25 7.00E-70 Supertig57479 3.00E-25 5.00E-48 Supertig75773 3.00E-25 1.00E-42 Supertig82755 4.00E-25 10000 Supertig99706 5.00E-25 5.00E-71 Supertig102092 5.00E-25 10000 Supertig81550 7.00E-25 5.00E-25 Supertig103691 7.00E-25 10000 Supertig79302 1.00E-24 6.00E-50 Supertig101123 1.00E-24 10000 Supertig102005 2.00E-24 1.00E-55 Supertig11280 2.00E-24 10000 Supertig105238 3.00E-24 1.00E-70 Supertig69047 3.00E-24 10000 Supertig69339 4.00E-24 3.00E-69 Supertig17649 7.00E-24 10000 Supertig102908 9.00E-24 7.00E-52 Supertig49708 1.00E-23 10000 Supertig6875 3.00E-23 3.00E-72 Supertig83587 3.00E-23 10000 Supertig487 3.00E-23 10000 Supertig41409 8.00E-23 10000 Supertig113311 1.00E-22 10000 Supertig26283 2.00E-22 1.00E-32 Supertig47066 3.00E-22 4.00E-38 Supertig7680 3.00E-22 10000 Supertig148605 5.00E-22 8.00E-77 Supertig747 5.00E-22 10000 Supertig1149 6.00E-22 10000 Supertig79038 7.00E-22 10000 Supertig6874 8.00E-22 3.00E-72 Supertig92693 8.00E-22 10000 Supertig107162 2.00E-21 5.00E-68 Supertig61222 2.00E-21 10000 Supertig1325 3.00E-21 10000 Supertig112640 4.00E-21 4.00E-71 Supertig62566 4.00E-21 10000 Supertig115470 7.00E-21 9.00E-73 Supertig121923 9.00E-21 1.00E-72 Supertig27857 9.00E-21 10000 Supertig80654 1.00E-20 3.00E-72 Supertig1580 1.00E-20 10000 Supertig82200 2.00E-20 8.00E-29 Supertig951 2.00E-20 2.00E-17 Supertig92895 2.00E-20 10000 Supertig94145 2.00E-20 10000 Supertig138881 3.00E-20 5.00E-72 Supertig105984 4.00E-20 10000 Supertig36902 5.00E-20 8.00E-08 Supertig137927 7.00E-20 2.00E-44 Supertig99665 8.00E-20 3.00E-70 Supertig141708 2.00E-19 5.00E-68 Supertig17291 2.00E-19 2.00E-43 Supertig154052 4.00E-19 2.00E-30 Supertig77995 5.00E-19 9.00E-70 Supertig759 5.00E-19 10000 Supertig17288 7.00E-19 3.00E-43 Supertig23622 1.00E-18 2.00E-70 Supertig81483 1.00E-18 2.1 Supertig87952 1.00E-18 10000 Supertig78915 1.00E-18 10000 Supertig58669 2.00E-18 10000 Supertig24683 3.00E-18 5.00E-50 Supertig1517 3.00E-18 10000 Supertig412 3.00E-18 10000 Supertig52534 4.00E-18 4.00E-71 Supertig63205 5.00E-18 10000 Supertig170664 5.00E-18 10000 Supertig151744 7.00E-18 5.00E-24 Supertig36 8.00E-18 10000 Supertig76727 1.00E-17 7.00E-09 Supertig35066 1.00E-17 10000 Supertig12086 1.00E-17 10000 Supertig37707 1.00E-17 10000 Supertig929 2.00E-17 0.2 Supertig20321 2.00E-17 10000 Supertig140 2.00E-17 10000 Supertig101974 3.00E-17 5.00E-24 Supertig65339 4.00E-17 10000 Supertig8390 5.00E-17 2.00E-70 Supertig789 8.00E-17 10000 Supertig155871 1.00E-16 2.00E-79 Supertig60291 1.00E-16 10000 Supertig99663 2.00E-16 3.00E-72 Supertig5157 2.00E-16 2.00E-28 Supertig101122 2.00E-16 10000 Supertig123588 2.00E-16 10000 Supertig15191 3.00E-16 2.00E-54 Supertig124134 3.00E-16 1.00E-50 Supertig20932 3.00E-16 10000 Supertig77233 5.00E-16 10000 Supertig169350 6.00E-16 3.00E-11 Supertig126135 9.00E-16 7.00E-68 Supertig21508 9.00E-16 5.00E-65 Supertig75089 1.00E-15 3.00E-70 Supertig11219 1.00E-15 10000 Supertig138832 2.00E-15 10000 Supertig102430 2.00E-15 10000 Supertig167831 3.00E-15 3.00E-61 Supertig132189 3.00E-15 1.00E-22 Supertig164261 3.00E-15 10000 Supertig450 3.00E-15 10000 Supertig135877 4.00E-15 0.32 Supertig152937 4.00E-15 10000 Supertig129781 4.00E-15 10000 Supertig29292 5.00E-15 10000 Supertig90189 5.00E-15 10000 Supertig136828 6.00E-15 8.00E-05 Supertig122565 6.00E-15 10000 Supertig156322 8.00E-15 10000 Supertig66500 1.00E-14 10000 Supertig59766 2.00E-14 10000 Supertig8769 2.00E-14 10000 Supertig64335 2.00E-14 10000 Supertig146277 3.00E-14 1.00E-34 Supertig168464 3.00E-14 10000 Supertig109705 4.00E-14 10000 Supertig26808 7.00E-14 10000 Supertig129514 7.00E-14 10000 Supertig46263 8.00E-14 4.00E-55 Supertig357 8.00E-14 10000 Supertig197297 1.00E-13 6.00E-53 Supertig105071 1.00E-13 10000 Supertig56786 1.00E-13 10000 Supertig92915 2.00E-13 10000 Supertig15556 2.00E-13 10000 Supertig62814 2.00E-13 10000 Supertig38011 3.00E-13 10000 Supertig99438 4.00E-13 10000 Supertig63479 4.00E-13 10000 Supertig156597 5.00E-13 7.00E-70 Supertig53949 5.00E-13 10000 Supertig205003 5.00E-13 10000 Supertig28824 6.00E-13 5.00E-55 Supertig56994 6.00E-13 10000 Supertig191130 6.00E-13 10000 Supertig84281 8.00E-13 10000 Supertig4964 9.00E-13 1.00E-73 Supertig27339 9.00E-13 1.00E-55 Supertig140209 1.00E-12 3.00E-72 Supertig179724 1.00E-12 3.00E-32 Supertig165944 1.00E-12 2.00E-30 Supertig144738 1.00E-12 10000 Supertig56160 1.00E-12 10000 Supertig213764 1.00E-12 10000 Supertig76623 2.00E-12 1.00E-59 Supertig51271 2.00E-12 3.00E-55 Supertig162390 2.00E-12 10000 Supertig1768 2.00E-12 10000 Supertig1851 3.00E-12 10000 Supertig29332 4.00E-12 10000 Supertig30238 4.00E-12 10000 Supertig181770 6.00E-12 6.00E-72 Supertig94100 6.00E-12 9.00E-54 Supertig1778 6.00E-12 10000 Supertig120124 7.00E-12 10000 Supertig159480 7.00E-12 10000 Supertig804 8.00E-12 10000 Supertig204396 1.00E-11 1.00E-69 Supertig167994 1.00E-11 5.00E-44 Supertig14690 1.00E-11 10000 Supertig125877 1.00E-11 10000 Supertig38099 2.00E-11 5.00E-11 Supertig31691 2.00E-11 10000 Supertig96391 4.00E-11 10000 Supertig128772 5.00E-11 8.00E-77 Supertig47046 5.00E-11 2.00E-64 Supertig44218 5.00E-11 3.00E-59 Supertig174563 5.00E-11 10000 Supertig165530 7.00E-11 2.00E-70 Supertig18964 7.00E-11 3.00E-56 Supertig73201 9.00E-11 2.00E-55 Supertig78818 9.00E-11 1.00E-48 Supertig43616 9.00E-11 10000 Supertig4635 2.00E-10 5.00E-52 Supertig170953 2.00E-10 2.00E-50 Supertig54556 2.00E-10 10000 Supertig69729 2.00E-10 10000 Supertig67277 3.00E-10 6.00E-56 Supertig95947 3.00E-10 2.00E-54 Supertig204172 3.00E-10 10000 Supertig133828 3.00E-10 10000 Supertig33194 3.00E-10 10000 Supertig166023 4.00E-10 10000 Supertig66590 5.00E-10 2.00E-78 Supertig180428 6.00E-10 3.00E-55 Supertig206134 7.00E-10 3.00E-72 Supertig195112 7.00E-10 1.00E-59 Supertig56121 7.00E-10 10000 Supertig187328 1.00E-09 5.00E-72 Supertig6175 1.00E-09 1.00E-54 Supertig132199 1.00E-09 10000 Supertig183025 1.00E-09 10000 Supertig150993 2.00E-09 4.00E-71 Supertig149815 2.00E-09 7.00E-54 Supertig42332 2.00E-09 10000 Supertig174649 4.00E-09 10000 Supertig45178 6.00E-09 7.00E-63 Supertig89756 7.00E-09 10000 Supertig32781 1.00E-08 4.00E-36 Supertig476 1.00E-08 10000 Supertig142023 1.00E-08 10000 Supertig19681 1.00E-08 10000 Supertig91111 1.00E-08 10000 Supertig117595 1.00E-08 10000 Supertig1530 1.00E-08 10000 Supertig120253 2.00E-08 1.00E-79 Supertig75800 2.00E-08 7.00E-47 Supertig82388 2.00E-08 1.00E-43 Supertig45060 2.00E-08 10000 Supertig143517 2.00E-08 10000 Supertig40628 3.00E-08 4.00E-71 Supertig136314 3.00E-08 10000 Supertig160827 4.00E-08 10000 Supertig235 4.00E-08 10000 Supertig2718 6.00E-08 10000 Supertig102774 7.00E-08 5.00E-39 Supertig59655 9.00E-08 7.00E-60 Supertig120771 9.00E-08 7.00E-55 Supertig67736 1.00E-07 10000 Supertig206756 2.00E-07 10000 Supertig34455 4.00E-07 10000 Supertig216362 4.00E-07 10000 Supertig188809 5.00E-07 2.00E-68 Supertig175566 5.00E-07 10000 Supertig36895 8.00E-07 10000 Supertig78297 8.00E-07 10000 Supertig102336 9.00E-07 10000 Supertig210902 1.00E-06 4.00E-38 Supertig78794 1.00E-06 10000 Supertig36194 1.00E-06 10000 Supertig140868 2.00E-06 3.00E-47 Supertig45861 2.00E-06 10000 Supertig18233 2.00E-06 10000 Supertig247 2.00E-06 10000 Supertig28469 2.00E-06 10000 Supertig227531 3.00E-06 2.00E-44 Supertig50460 3.00E-06 10000 Supertig98070 4.00E-06 1.00E-52 Supertig170438 4.00E-06 10000 Supertig214478 4.00E-06 10000 Supertig197331 5.00E-06 8.00E-32 Supertig362 5.00E-06 3.8 Supertig68213 5.00E-06 10000 Supertig887 5.00E-06 10000 Supertig379 6.00E-06 2.00E-53 Supertig65026 6.00E-06 10000 Supertig23133 1.00E-05 10000 Supertig64131 1.00E-05 10000 Supertig167 1.00E-05 10000 Supertig80349 1.00E-05 10000 Supertig178275 1.00E-05 10000 Supertig77294 1.00E-05 10000 Supertig3100 2.00E-05 5.00E-39 Supertig45348 2.00E-05 3.00E-06 Supertig175279 2.00E-05 10000 Supertig51343 2.00E-05 10000 Supertig216190 2.00E-05 10000 Supertig53999 2.00E-05 10000 Supertig5891 3.00E-05 2.00E-24 Supertig78154 3.00E-05 2.00E-07 Supertig93827 3.00E-05 10000 Supertig74646 3.00E-05 10000 Supertig32967 3.00E-05 10000 Supertig101950 4.00E-05 1.00E-39 Supertig165160 4.00E-05 4.00E-39 Supertig167066 5.00E-05 3.00E-36 Supertig119462 6.00E-05 10000 Supertig193443 7.00E-05 3.00E-38 Supertig101246 7.00E-05 10000 Supertig97391 7.00E-05 10000 Supertig53623 9.00E-05 10000 Supertig62657 1.00E-04 1.00E-62 Supertig171340 1.00E-04 2.00E-44 Supertig69309 1.00E-04 4.00E-42 Supertig7418 1.00E-04 10000 Supertig86658 1.00E-04 10000 Supertig72531 1.00E-04 10000 Supertig62888 1.00E-04 10000 Supertig30014 1.00E-04 10000 Supertig108700 2.00E-04 10000 Supertig19298 2.00E-04 10000 Supertig61425 2.00E-04 10000 Supertig105070 3.00E-04 10000 Supertig868 3.00E-04 10000 Supertig129544 4.00E-04 3.00E-40 Supertig111 4.00E-04 10000 Supertig26829 4.00E-04 10000 Supertig92320 4.00E-04 10000 Supertig7304 4.00E-04 10000 Supertig72760 5.00E-04 10000 Supertig37638 5.00E-04 10000 Supertig72777 6.00E-04 10000 Supertig11597 6.00E-04 10000 Supertig219247 6.00E-04 10000 Supertig56189 7.00E-04 10000 Supertig97366 8.00E-04 10000 Supertig35783 8.00E-04 10000 Supertig12669 8.00E-04 10000 Supertig116302 9.00E-04 10000 Supertig148370 0.001 2.00E-42 Supertig1448 0.002 5.00E-36 Supertig178739 0.004 2.00E-31 Supertig211797 0.007 2.00E-25 Gene Models Supertig29949 >Strong1.2 gi|13430191|gb|AAK25762.1|AF335483_1 toll-like receptor Tlr1.2 [Strongylocentrotus purpuratus] MAFIRQAPFLRCLPLVLLCILTPTLIQTIHQDAMLTSSMKCHYDAEQKEADCSDRGLDSIPQNLPDDIEELDLKFNKITFILSSSFMRYPLIQVLDFSSNDIRMIESASFYPLKELNRLDLPFNHNLVFPATDLFRWSRNLSILKLYGSNLKLLPNDTLKWSPSVESIYLRFNKLTFVNMSLCGRAKKISLAYNKIEHLTAESFIIGCQSDYIDLTGNPIKSVDPNVIASLRVRSLVLGEYPLTLEVLKDTFIGICRSEIVELTINGANFTVLPRDFFSPLRNCSPPVLKFTGNNLQSLSQNVFSNLTRLVELDLSHNEIQALSPYVFSNLTRLVELDLSFNEIQSLSPYVFSNLTRLVELDLSQNKIITVEPVFYQGMRGLKVLNLNFNQIKYINPNTDEWTLDLNELYLRSNSLTEISEFAFFGLRNLTLLDLSFNKDLIVLNITSSSKLTGIQTIALNFCNFCDMDIFQPVAPNLTTLFMNNMIAEMIMMAPGITFEDSQGLENLEIRNSGLSNFNIWDEILNTSLFDGLSNLITLDLSQNYFDFYFPDDFPARIFKQLSALQNLSLEACHISCLHPLAFTGLESLRVLNLSGNVIQQLNFDIFKMLDQVTIIDLHDNLLAYLDEQLFSNNPRLTTLLLSNNKLTLLNQKTFEPIESSLLSFDLSLNPIDCNCDLRWFRDWMSGHIDVIDKNRTICSSASLQPLREKPLLDFDPNKLCGLNIGLVVMTPLAGIFLGVIVAIFYHNRLQLKYKLFLLKLMVIGYKEMRDARDHNDYEFDLNIIFYEDDEEWVRQQLQPALEERLPQFQRNVFGDQDLILGMHYLDAVDYVVSHSYKTLILLSRAAVHDRWFMLKLRTAMDHVSDTQTEFVVVVFLEDFPDEDIPFLARLYLSDGRPYQHWTEDVGGHVFFWNALVKNLTINLRTNDFIPNE Supertig63355 >Strong1.1 gi|13430189|gb|AAK25761.1|AF335482_1 toll-like receptor Tlr1.1 [Strongylocentrotus purpuratus] MSFKHPSSLFPSLVMAFLLPLTLQAFQGDSMEIVSSGLHTGSVRRGCYQNVEQRRAYCSSRGLDSVLQNLAEDTNELDLSENNITVLPKFSFRRYPLITDLDLSANDIRVIEPTAFHPLKKLVNLSIIANRNLVLPVSGLFRWASKLTLLNLSGSNLKSLPNDTLKWNQHIDYLDLGFNHLTFINISTCGSVRYAGFAYNHIEQLTKETFTFGCQTDHLELGNNPIKLIDPIAIAALHTHSLILIYAGGHSWTPEMLRNLTIGISRSHIKSLKVDVNLGHFPQDVFTPLRDYSFTLLDFSYNKVNALFPFVFSNLTLLDQLDLSNNKIATIEPNFFDSMQALKVLNINFNQVRSINTGNHTWTINLIKLYLSTNSLTEISKFAFLGLQNLTLLDLSFNRRLASIYLTSFTGLDNIHTIDLSGCSIRYLQLYTPVLRSLYMKRNYLFGAPINPLEPGKSFKDSTNLVYLDIQESQVFPYNLWDPATNVSLFEGLFNLTTLDMSKNPNIGKFGLDLGIFHHLSALQELSLDACAISNLHPLVFTGLDSLQKLNLSGNNLEQIRIGLLTGLGQIRSIKLDGNILALLDERTFLNKSRLTSLSLANNKLTFLNESIFRPIYTSLSLVDFSQNPLICTCDLEWLLHWLNQNGTVRLANENQTLCAPSSLASLREKPLLHFNPSELCRFNYAIFSLIPIVIVSLVVLLALVYHQRWRLRYKLFLLKLAVIGYRGEAIDARDHNDYEFDVNIIFYDDDEEWIRDNLRPTLEVQLPQFQRNTFGDADLIPGMYYLDAVDYVVSRSYKTIILLSRAAVRDRWFMLKFRTAMNHVSDTQTEFVVVVFLEDIPDDEIPFLARLFLSDGRPYLHWTEDVRGQEYFWNELAKNLTINLRTNDLIPNE Supertig756 >Strong2.1 gi|13384079|gb|AAK21261.1| toll-like receptor Tlr2.1 [Strongylocentrotus purpuratus] partial missing N-terminus EKTEYRSEVEEIQQEDFLPLQNTTISNLTLTANKIQILQPQSFLHLNFIQEILLGGNQINSFDIQPSLGMTYIEHLSLIGCQIHDLLPPDFASNLSVTYPTIRTLTLSANKIETVQEGAFWGFTTLEVLSLNLNQLKVLTNQSFCRLESLTELDISNNKLTSFTNGTFTCLQSLKQLNASGNLLQTLSPGYFYGMSSILTISLSSNRIDALNNDQQLWAIKTLRMLDISNNALKGVSKGRFNGLTNLEALNISGNNINYYSYTAFTGLLNLKELYLENERAAFLENSFCQLHTLLFLDLSNAPIQVSPTSIEQFFNMSSLRELRMEKAQLKDTDLYDKDKHQSLFTGLFSLRTLQIKDNYLHDLDVRIFQNLSQLVHLDMSNSRIHTLRSGLFSPLPSLRYLYIGENNLVEVPGDIFNGLFRLNVLTFQNNILSSLDPKTFAQTLRLTDLYLPGNQISTIKPGTVLPGNTSLRLDISNNPFSCTCSLAWFRQWLDSADIDVKHADQTLCSGTSLKGLSKQPILSFHPEDHCGVNIFLIAGISFTCIFLFLITLLAYNRRWWLNHKFFLLKLAVVGYEEMAEDFDADNYEFHLNLMFLEEEEEWVDRVIKPALEERFPHLQNIIYGDKDLHLGMFYINAINDALDNSFKTVLLISNQSIRDAWCMTKLRMALEHLNETGLDKIILIFLEDIEDENLPYLVRLFMSRNKPYMLWTDDEDGQELFWAQFEKSMRANKAINNAIPL Genbank My short name TLR Digit Species common name Species scientific name Accession # Notes SpTLR1.1 1.1 sea urchin Strongylocentrotus purpuratus AAK25761 SpTLR1.2 1.2 sea urchin Strongylocentrotus purpuratus AAK25762.1 SpTLR2.1 2.1 sea urchin Strongylocentrotus purpuratus AAK21261.1 partial; missing N-terminus