Phosphoinositide 3-kinase and Bruton's tyrosine kinase regulate overlapping sets of genes in B lymphocytes -- Data Supplement - Supporting Information -- Proceedings of the National Academy of Sciences

Supporting information for Fruman et al. (December 26, 2001) Proc. Natl. Acad. Sci. USA, 10.1073/pnas.012605099.

Supporting Figure 5

Fig. 5.
Additional quantitative real-time PCR (Q-PCR) results for genes whose expression changed significantly (P< 0.01) in wild-type cells. Down-regulation of CD2 mRNA was modestly but significantly (P = 0.005) affected in PI3K-low, but this was not verified by Q-PCR; nevertheless, the overall pattern across conditions looked similar. Gfi-1, Enx-1, Stat4, and glutamic acid decarboxylase (GAD) appeared PI3K- and/or Btk-dependent, based on K-means clustering rather than statistical criteria. Data are presented in the same format as Fig. 2.