Amado et al. 10.1073/pnas.0504388102. |
Movies 1–4. Representative movies illustrating the effect of mesenchymal stem cell (MSC) therapy on global ventricular function. (A and B) Short-axis cine images obtained from a nontreated animal »10 d (A) and 8 weeks (B) after myocardial infarction (MI). As depicted, there is a large anteroseptal region of akinesis 10 d after MI (A). Further deterioration occurs 8 weeks after MI (B), marked by thinning and dyskinesis of the specific area (please note the myocardial hyperenhanced region due to gadolinium retention). (C and D) Short-axis cine images obtained from an animal treated with MSCs. At 10 d after MI, there is a clear presence of akinesis at the anteroseptal region (C); however, MSC treatment restores the contractile function to near-normal levels 8 weeks later (D). This animal did not receive gadolinium.
Movie 1. Representative movie illustrating the effect of MSC therapy on global ventricular function. Short-axis cine images obtained from a nontreated animal »10 d after MI. As depicted, there is a large anteroseptal region of akinesis 10 d after MI.
Movie 2. Representative movie illustrating the effect of MSC therapy on global ventricular function. Short-axis cine images obtained from a nontreated animal »8 weeks after MI. Further deterioration occurs 8 weeks after MI, marked by thinning and dyskinesis of the specific area (please note the myocardial hyperenhanced region due to gadolinium retention).
Movie 3. Short-axis cine image obtained from an animal treated with MSCs. At 10 d after MI, there is a clear presence of akinesis at the anteroseptal region.
Movie 4. Short-axis cine image obtained from an animal treated with MSCs. MSC treatment restores the contractile function to near-normal levels 8 weeks later.