Ahmed et al. 10.1073/pnas.0504438102.

Supporting Table

Files in this Data Supplement:

Supporting Table 1




Table 1. Escalation (ESC) genes found by using four analysis strategies

Gene name

Probe set ID

ANOVA

SAM

Brain

region

Direction

of change

MAS4

MAS5

dChip

RMA

Growth/structure/plasticity

 

 

 

 

 

 

 

Delta 2 catenin (Ctnnd2)*

AB008752_at

X

 

 

 

LH

↑

Microtubule-associated protein 1A (MAP-1A)*

M83196_at

X

X

X

X

LH

↑

Fibroblast growth factor receptor 1 (Fgfr1)*

D12498_s_at

X

X

 

X

LH

↑

S54008_i_at

X

X

 

X

LH

↑

Bcl-x alpha (Bcl-2 like 1)*

U72350_at

X

X

 

X

LH

↑

Bcl-x alpha Short (splice variant)*

S78284_s_at

X

X

 

X

LH

↑

Bcl-x alpha Long (splice variant)*

U34963_s_at

X

X

X

X

LH

↑

Lifeguard/ Neural membrane protein 35 (NMP35)

AF044201_at

X

X

X

X

LH

↑

Purkinje cell protein 4 (Pcp4, PEP-19)

M24852_at

X

X

 

 

LH

↓

Neurofilament, light polypeptide (NF-L)*

M25638_s_at

X

 

 

 

NAc

↓

Microtubule-associated protein 2 (MAP-2)

rc_AI228850_s_at

X

 

 

 

NAc

↓

Caspase 2 (Casp2, Ich-1, Nedd2)*

U77933_at

X

X

 

 

NAc

↑

BOD-L/BCL2-like gene 11 (apoptosis facilitator)*

AF065433_at

 

X

 

 

SP

↑

insulin-like growth factor binding protein-2, exon 1*

M91595exon_s_at

 

 

 

X

SP

↓

Insulin-like growth factor 2 (IGF2)

X17012mRNA_s_at

X

 

 

X

AMY

↓

Neurodap1*

rc_AA894089_s_at

 

 

X

 

VTA

↓

Transferrin (Tf)*

U31866_g_at

 

 

X

 

VTA

↓

Neurotransmitters/receptors/enzymes/signal transduction

Glutamate receptor NMDA2D (Grin2d)*

D13213_s_at

X

X

X

 

LH

↑

U08260_at

X

X

 

 

LH

↑

Neurofibromin/ Neurofibromatosis 1 (Nf1)*

D45201_at

X

 

 

LH

↑

Glutamate receptor interacting protein 2 (GRIP2)*

AF090113_at

X

 

 

 

LH

↑

Activity and neurotransmitter-induced early gene 6 (ania-6)*

AF030091UTR#1_g_at

 

X

 

 

LH

↑

Guanine nucleotide binding protein, beta 1 (Gnb1, rGbeta1)*

rc_AI227660_s_at

 

X

 

 

LH

↓

U88324_at

 

X

 

 

LH

↓

Adrenergic receptor kinase beta-1 (AdrbK1)

S48813_s_at

X

X

 

 

LH

↑

Glutamate-binding protein (GBP, Grina)

S61973_at

X

X

X

X

LH

↑

S61973_g_at

X

X

 

 

LH

↑

Phospholipase D2 (Pld2)

rc_AA998338_s_at

X

X

 

 

LH

↓

Protein kinase C, gamma (PKCg , Prkcc)*

X07287cds_s_at

 

X

X

X

LH

↑

Inositol 1,4,5-trisphosphate 3-kinase B (Itpkb)

X74227cds_at

X

 

X

X

LH

↑

metabotropic glutamate receptor 7 (mGluR7, Grm7)*

D16817_g_at

 

X

 

 

NAc

↑

5-Ht receptor 2C (5-HT2C)

M21410_s_at

X

X

 

 

NAc

↓

Gamma-aminobutyric acid (GABA) B receptor, 1 (Gabbr1)*

AB016160_g_at

X

 

 

X

SP

↓

AB016161UTR#1_g_at

X

 

 

 

SP

↓

rc_AA926213_g_at

X

 

 

X

SP

↓

Neuropeptide Y (NPY)*

M15880_at

X

 

 

 

SP

↓

Neuronal pentraxin receptor (Nptxr)*

rc_AI045501_s_at

X

 

 

 

SP

↓

Guanine nucleotide binding protein, beta 1 (rGbeta1, Gnb1)*

U88324_g_at

X

 

 

 

SP

↑

Ion pumps/channels

K+ voltage-gated channel, shaker related, member 6 Kv1.6 (KCNA6)*

M27159cds_s_at

X

X

 

X

LH

↑

K+ inward rectifier 10 Kir4.1 (KCNJ10)*

X83585cds_s_at

 

X

 

 

LH

↑

U27558_at

 

X

 

 

LH

↑

ATPase, Na+/K+ transporting, beta 2 polypeptide (Atp1b2)*

D90048exon_g_at

X

X

X

X

LH

↑

J04629_at

X

X

X

X

LH

↑

ATPase, Na+/K+ transporting, alpha 3 polypeptide (Atp1a3)*

M28648_s_at

X

 

 

 

LH

↑

Vesicular inhibitory amino acid transporter (5VIAAT)

AF030253_at

X

X

 

 

LH

↑

rc_AA996551_s_at

X

X

 

X

LH

↑

K+ voltage gated channel, Shal-related, member 2 Kv4.2 (KCND2)*

M59980_s_at

X

 

 

 

SP

↓

Na+ channel, voltage-gated, type II, beta polypeptide (SCNB2)*

U37147_at

X

 

 

 

AMY

↑

ATPase, Na+/K+ transporting, alpha 3 polypeptide (Atp1a3)*

M28648_s_at

X

X

 

 

VTA

↑

Release machinery

Synaptotagmin 11 (Syt11)

AF000423_at

X

X

X

X

LH

↑

Synaptotagmin 3 (Syt3)*

D28512_at

X

X

 

X

LH

↑

Syntaxin 1B2 (Stx1b2)

M95735_at

X

 

X

X

LH

↑

Synaptophysin (Syp)*

X06655_at

 

 

X

X

LH

↑

RAB3A

X06889cds_at

X

X

X

X

LH

↑

Tissue/response

Fractalkine/ chemokine (C-X3-C motif) ligand1 (Cx3cl1)*

AF030358_at

X

X

 

 

LH

↑

rc_AA800602_s_at

X

X

 

 

LH

↑

rc_AI227647_s_at

X

 

 

 

LH

↑

NAc, nucleus accumbens; AMY, amygdala; LH, lateral hypothalamus; SP, septum; VTA, ventral tegmental area.

*Validated by RT-PCR.