CLUSTAL W (1.81) multiple sequence alignment Helicobacter_pylori -------------------------------------------------- Thermotoga_maritima -------------------------------------------------- Deinococcus_radiodurans -------------------------------------------------- Treponema_pallidum -------------------------------------------------M Trichomonas_vaginalis ------------------------------------------------MA Rhizobium_meliloti -------------------------------------------------- Rhodobacter_sphaeroides -------------------------------------------------- Caulobacter_crescentus -------------------------------------------------- Pseudomonas_stutzeri -------------------------------------------------- Neisseria_meningitidis -------------------------------------------------- Alcaligenes_eutrophus -------------------------------------------------- Xanthobacter_flavus -------------------------------------------------- Nostoc_commune -------------------------------------------------- Synechocystis_sp. -------------------------------------------------- Cyanophora_paradoxa TTAPVVISRTAPSVASKKSEVCQAKAGFLKGGRRLGFFLNNVQAPKNNEG Giardia_lamblia -------------------------------------------------- Bacillus_subtilis -------------------------------------------------- Mycoplasma_pneumoniae -------------------------------------------------- Escherichia_coli --------------------------------------MSK---IFDFVK Haemophilus_influenzae --------------------------------------MAK---LLDIVK Campylobacter_jejuni ---------------------------------------MG---VLDIVK Borrelia_burgdorferi ---------------------------------------MG---VLDKIK Schizosaccharomyces_pombe ---------------------------------------MG---ILDIVP Saccharomyces_cerevisiae ---------------------------------------MG---VEQILK Neurospora_crassa ---------------------------------------MRCPIPEHKQN Mycobacterium_leprae -------------------------------------------------- Streptomyces_galbus -------------------------------------------------- Helicobacter_pylori ------MLVKGNEILLKAHKEGYGVGAFNFVNFEMLNAIFEAGNEENSPL Thermotoga_maritima --VTMPYVKNTKEILEKASKERYAIGAFNFNNMEFLQAILEAAEEEKAPV Deinococcus_radiodurans ------MLVTGKDILVPARAGKYAVGAFNTNNMEITQAIIHTAEKLRSPV Treponema_pallidum TSYKALGLVNTKDLFAKAVKGGYAIPAYNFNNLEQLQAIIQACVETRSPV Trichomonas_vaginalis VSYKSLGLVNSKDIFAKAVNGGYAIPGYNFSNLEQLQAIITASVKTESPV Rhizobium_meliloti -----MARITLRQLLDHAAERSYGVPAFNINNMEQGLAIMEAARACDAPV Rhodobacter_sphaeroides -----MALITLRQLLDHAAEQGYGVPAFNINNMEQGLAIMEAARACDAPV Caulobacter_crescentus -----VARITLRQLLDHAAEHEYGLPAFNINNMEQGLAIMEAADAVNSPV Pseudomonas_stutzeri -----MALISMRQMLDHAAEFGYGVPAFNVNNLEQMRAIMEAADKTDSPV Neisseria_meningitidis -----MALVSMRQLLDHAAENSYGLPAFNVNNLEQMRAIMEAADQVNAPV Alcaligenes_eutrophus -----MALISLRQLLDHAGEFGYDVPAFNVNNLEQIHAIMEAAQETDSPV Xanthobacter_flavus -----MALVSMRQLLDHAADDSYGLPAFNVNNMEQVKAIMDAARATSSPV Nostoc_commune -----MALVPLRLLLDHAAENGYGIPAFNVNNLEQIQAILKAAVETDSPV Synechocystis_sp. -----MALVPMRLLLDHAAENGYGIPAFNVNNMEQIISIMQAADETDSPV Cyanophora_paradoxa AEVTRMALVPMRILLDHAAEHGYGLPAFNVNNMEQIKSIMEAAKATNSPV Giardia_lamblia -----MPLCTLRQMLGEARKHKYGVGAFNVNNMEQIQGIMKAVVQLKSPV Bacillus_subtilis -----MPLVSMTEMLNTAKEKGYAVGQFNLNNLEFTQAILQAAEEEKSPV Mycoplasma_pneumoniae ------MLVNIKQMLQHAKQHHYAVPHININNYEWAKAVLTAAQQAKSPI Escherichia_coli --PGVITGDDVQKVFQVAKENNFALPAVNCVGTDSINAVLETAAKVKAPV Haemophilus_influenzae --PGVVTGEDVQKVFAYAKEHNFAIPAVNCVGSDSVNAVLETAARVKAPV Campylobacter_jejuni --AGVISGDELNKIYDYAKAEGFAIPAVNVVGTDSINAVLEAAKKVNSPV Borrelia_burgdorferi --PGVVYGKELHFLYEICKKEGFAIPSINCIGTNSINAVLEAAKEINSPI Schizosaccharomyces_pombe --TGVIAGDNVLKLFTYAREHGFAIPAINVTSSSTAIAALEAAREARSPI Saccharomyces_cerevisiae RKTGVIVGEDVHNLFTYAKEHKFAIPAINVTSSSTAVAALEAARDSKSPI Neurospora_crassa LTFSLPLGDDVLKLFQYAREKQFAIPACNVTSSSTAVAALEAARDQKAPS Mycobacterium_leprae --MPIATPEIYAEMLRRAKENSYAFPAINCTSSETVNAAIKGFADAGSDG Streptomyces_galbus --MPIATPEVYNEMLDRAKAGKFAYPAINVTSSQTLNAALRGFAEAESDG : . : * . . . : : Helicobacter_pylori FIQTSEGAIKYMG-----------------IDMAVGMVKTMCERYPH--- Thermotoga_maritima IVATSEGAIKYIGKGDIETG----------AKLAVEMVRTYAEKLS---- Deinococcus_radiodurans IVQMSEGAIKYGG-----------------QDLAN-IVIDLATRAT---- Treponema_pallidum ILQVSSGARKYAN-----------------ATLLRNMARGAVEYAHELGV Trichomonas_vaginalis ILQVSAGARKYAN-----------------QTMLRYMAQGAAEFAKEIHP Rhizobium_meliloti ILQVSRGARSYAN-----------------DIMLAKMMEALEVMYPD--- Rhodobacter_sphaeroides IIQASRGARSYAN-----------------DIMLAKMIEALAAIYPE--- Caulobacter_crescentus IIQASRGARNYAN-----------------DIMLAKMIDALVDIYPH--- Pseudomonas_stutzeri IVQASAGARKYAG-----------------APFLRHLILAAIEEFPH--- Neisseria_meningitidis IVQASAGARKYAG-----------------APFLRHLILAAVEEFPH--- Alcaligenes_eutrophus ILQASAGARKYAG-----------------EAYLRHMVLAAAETHPD--- Xanthobacter_flavus ILQGSAGARKYAG-----------------EPFLRHLIAAAVEAYPE--- Nostoc_commune ILQASRGARAYAG-----------------ENFLRHLILAAVETYPH--- Synechocystis_sp. ILQASRGARSYAG-----------------ENFLRHLVLGAVETYPH--- Cyanophora_paradoxa ILQASRGARSYAG-----------------ENFLRHLILAAAETYPE--- Giardia_lamblia ILQCSRGALKYSD-----------------MIYLKKLCEAALEKHPD--- Bacillus_subtilis ILGVSEGAGRYMG------G----------FKTVVAMVKALMEEYKVT-- Mycoplasma_pneumoniae IVSTSEGALKYISG----------------HQVVVPMVKGLVDALKIT-- Escherichia_coli IVQFSNGGASFIAGKGVKSD-VPQGAAILGAISGAHHVHQMAEHYGVPVI Haemophilus_influenzae IIQFSNGGAAFYAGKGIKPT-SGTRPDVLGAIAGAKQVHTLAKEYGVPVI Campylobacter_jejuni IIQFSNGGAKFYAGKNCP------NGEVLGAISGAKHVHLLAKAYGVPVI Borrelia_burgdorferi MIQFSNSGSAFISGKGLKME-KPQGVSIVGAISGAMHVHLMAEHYGVPVV Schizosaccharomyces_pombe ILQTSNGGAHFFAGKESSNEGQKA--SIAGSIAAAHYIRSIAPFFGVPVV Saccharomyces_cerevisiae ILQTSNGGAAYFAGKGISNEGQNA--SIKGAIAAAHYIRSIAPAYGIPVV Neurospora_crassa SLQTSQGCAAFFAGKGIKDSAEKARDSVAGAIAAAHYIRSIAPIYGIPVV Mycobacterium_leprae IIQFSTGGAEFASGLGVKD-------MVTGAVALAKFTHTIAAKYPINVA Streptomyces_galbus IVQISTGGAEFLGGQYSKD-------MVTGAVALAEFAHIIAEKYPVNIA : * . : Helicobacter_pylori -----------IPVALHLDHGTTFESCEKAVKAGFTSVMIDAS------- Thermotoga_maritima -----------VPVALHLDHGRDFKVIMAAIKAGYSSVMIDAS------- Deinococcus_radiodurans -----------VPVALHLDHGSSYESALNAIKMGFTSVMIDAS------- Treponema_pallidum -------D---IPIVLHLDHGDSLELCIDCIESGFSSVMIDGS------- Trichomonas_vaginalis -------EHKLIPIVLHLDHGDSFELCKSCIDLGFSSVMIDGS------- Rhizobium_meliloti -----------IPLCIHQDHGNNVPNCLTAIQHGFN-LRDDGRFAEGGCE Rhodobacter_sphaeroides -----------IPLCMHQDHGNNEATCMTAIRHGFTSVMMDGSLKAD-AK Caulobacter_crescentus -----------IPVCMHQDHGNGPATCATAIQYGFTSVMMDGSLMED-AK Pseudomonas_stutzeri -----------IPVCMHQDHGTSPDVCQRSIQLGFSSVMMDGSLRED-GK Neisseria_meningitidis -----------IPVVMHQDHGASPDVCQRSIQLGFSSVMMDGSLMED-GK Alcaligenes_eutrophus -----------IPIVLHQDHGSSPAICQASIRSGFTSVMMDGSLRED-MK Xanthobacter_flavus -----------IPVVMHQDHGASPAVCMGAIKSGFSSVMMDGSLKED-GK Nostoc_commune -----------IPIVMHQDHGNAPATCYSAIKNNFTSVMMDGSLEAD-AK Synechocystis_sp. -----------IPIAMHQDHGNSPATCYSAIRNGFTSVMMDGSLEAD-AK Cyanophora_paradoxa -----------IPIAMHQDHGNGPATCLSAIRNGFTSVMMDGSLEED-SK Giardia_lamblia -----------IPICIHLDHGDTLESVKMAIDLGFSSVMIDAS------- Bacillus_subtilis -----------VPVAIHLDHGSSFESCAKAIHAGFTSVMIDAS------- Mycoplasma_pneumoniae -----------VPVALHLDHG-SYEGCKAALQAGFSSIMFDGS------- Escherichia_coli -LHTDHCAK-KLLPWIDGLLDAGEKHFAATGKPLFSSHMIDLS------- Haemophilus_influenzae -LHTDHAAK-KLLPWIDGLLDAGEKHFAETGRPLFSSHMIDLS------- Campylobacter_jejuni -LHTDHAAR-KLLPWIDGLIEANAQYKKTHGQALFSSHMLDLS------- Borrelia_burgdorferi -LHTDHCAK-NLLPWVEGLLEYGEKYYSQHKKPLFSSHMLDLS------- Schizosaccharomyces_pombe -MHSDHCAK-KLLPWMDGMFEADEAYFKIHGEPLFSSHMLDLS------- Saccharomyces_cerevisiae -LHSDHCAK-KLLPWFDGMLEADEAYFKEHGEPLFSSHMLDLS------- Neurospora_crassa RIHTDHCAK-KLL-FGDGIPEEDEKFFKANGVPLFSSHMIDLS------- Mycobacterium_leprae -LHTDHCPKDKLDSYVRPLLAISARRVATGKDPLFGSHMWDGS------- Streptomyces_galbus -LHTDHCPKDKLDGYVRPLLALSKKRVEAGLGPLFQSHMWDGS------- : : : * . . Helicobacter_pylori -HHAFEENLELTSKVVKMAHNAG--VSVEAELGRLMGIEDNI-------- Thermotoga_maritima -HLPFEENLRETKRIVEIAHAVG--ISVEAELGKLKGIEDN--------- Deinococcus_radiodurans -HHPFEENVHETKRVVEAAHAMG--ISVEAELGRLGGIEEHV-------- Treponema_pallidum -ALPYDENVALSRKVCEYAHARADYVTVEGELGVLAGVE----------- Trichomonas_vaginalis -HHPYDENVALTKKVVEYAHSRPDYVTVEGELGVLAGVE----------- Rhizobium_meliloti DACRLRYNAMITTEVSRLAHMVG--ASVEGELGCLGSLETGHGEAEDGHG Rhodobacter_sphaeroides TPADYDYNVDITARVSHMAHWVG--ASVEGELGVLGSLETGESEAEDGHG Caulobacter_crescentus TPASYEYNVEVTRKVVQMAHSCG--VSVEGELGVLGSLETGMGEAEDGHG Pseudomonas_stutzeri TPADYDYNVRVTQQTVAFAHACG--VSVEGELGCLGSLETGMAGEEDGVG Neisseria_meningitidis TPSSYEYNVNATRTVVNFSHACG--VSVEGEIGVLGNLETGEAGEEDGVG Alcaligenes_eutrophus TPSDYDYNVEVTRRVCEMAHAIG--VSVEGELGCLGSLETGQAGEEDGVG Xanthobacter_flavus TPADYDYNVSVTAKVVELAHAVG--VSVEGELGCLGSLETGKGEAEDGHG Nostoc_commune TPASFEYNVNVTREVVNVAHALG--VSVEGELGCLGSLETGAGEAEDGHG Synechocystis_sp. TPASFEYNVNVTAEVVKVAHSVG--ASVEGELGCLGSLETGQGEAEDGHG Cyanophora_paradoxa TPASYEYNVNVTKTVCDLAHAVG--VSVEGELGCLGNLETGQGDKEDGVG Giardia_lamblia -HHPFDENVRITKEVVAYAHARS--VSVEAELGTLG-------------G Bacillus_subtilis -HHPFEENVATTAKVVELAHFHG--VSVEAELGTVGGQE----------- Mycoplasma_pneumoniae -HLPFQENFTKSKELIELAKQTN--ASVELEVGTLGGEE----------- Escherichia_coli -EESLQENIEICSKYLERMSKIG--MTLEIELGCTGGEEDGVD------- Haemophilus_influenzae -EESMEENMAICREYLARMDKMG--MTLEIEIGITGGEEDGVD------- Campylobacter_jejuni -EESLEENLSTCEVYLQKLDALG--VALEIELGCTGGEEDGVD------- Borrelia_burgdorferi -EEPIKENIEISKKFLERMAKIE--MFLEIELGITGGEEDGVD------- Schizosaccharomyces_pombe -EEPKKENIAQVKEYCKRAVPMK--IWIEMEIGITGGEEDGVD------- Saccharomyces_cerevisiae -EETDEENISTCVKYFKRMAAMD--QWLEMEIGITGGEEDGVN------- Neurospora_crassa -EEPVEENISTCVKYLKRMAPMK--QWLEMEIGITGGEEDGVD------- Mycobacterium_leprae -AIPIDENLAIAQDLLKDAAAAK--IILEVEIGVVGGEEDGVA------- Streptomyces_galbus -AEPLADNLAIAQELLETARAAQ--IILEVEITPTGGEEDGVS------- * :* *: . . ... . Helicobacter_pylori --SVDEKDAVLVNPKEAEQFVKES-----QVDYLAPAIGTSHGAFKFKGE Thermotoga_maritima ---VVEKESVLVDPEEAKVFVKET-----EVDFLAPAIGTSHGAFKFKGE Deinococcus_radiodurans --VVDEKDAFLTDPDEAVKFVEET-----GTDYLAIAIGTSHGAYKGKGR Treponema_pallidum -DDVVAEKSHYTMPDEVEDFVKKT-----GVDSLAISIGTSHGRAKFTPE Trichomonas_vaginalis -DDVKAEKHTYTRPEEVQDFVSKT-----GVDSLAIAIGTSHGAYKFPPG Rhizobium_meliloti FEGALDRSQLLTDPDEAARFVAET-----GVDALAVAIGTSHGAYKFTRK Rhodobacter_sphaeroides AEGKLDHSQLLTDPDQAVDFVKKT-----QVDALAIACGTSHGAYKFSRK Caulobacter_crescentus FEGKLSHDELLTDPDQAVDFVAQT-----GVDALAIAMGTSHGAYKFTRK Pseudomonas_stutzeri AEGVLDHSQLLTDPEEAADFVAKT-----KVDALAIAIGTSHGAYKFTNP Neisseria_meningitidis AVGKLSHDQMLTSVEDAVRFVKDT-----GVDALAIAVGTSHGAYKFTRP Alcaligenes_eutrophus AAGTLSHDMMLTDPAQARDFVART-----GVDALAIAIGTSHGAYKFSRK Xanthobacter_flavus AEEALDHSKLLTDPDEAAQFVKAT-----QCDALAIAIGTSHGAYKFTRK Nostoc_commune FEGTLDHSQLLTDPDEAVEFVEAT-----QVDALAVAIGTSHGAYKFTRK Synechocystis_sp. FEGKLDHSQLLTDPEEAVEFVNKT-----QVDALAVAIGTSHGAYKFTRK Cyanophora_paradoxa AEGVLTIEQMLTDPAQAKDFVERT-----KVDALAIAIGTSHGAYKFSRK Giardia_lamblia IEEDVQNTVQLTEPQDAKKFVELT-----GVDALAVAIGTSHGAYKFKSE Bacillus_subtilis -DDVIAEGVIYADPKECQELVERT-----GIDCLAPALGSVHGPYKGEPN Mycoplasma_pneumoniae -DGIVGQGELAN--IEECKQIATL-----KPDALAAGIGNIHGLYPDNWK Escherichia_coli -NSHMDASALYTQPEDVDYAYTEL-SKISPRFTIAASFGNVHGVYKPGNV Haemophilus_influenzae -NSDVDESRLYTQPSDVLYVYDQL-HPVSPNFTVAAAFGNVHGVYKPGNV Campylobacter_jejuni -NTGIDNSKLYTQPEDVALAYERL-GKISDKFSIAASFGNVHGVYKPGNV Borrelia_burgdorferi -NSDRALHELFSTPEDIYYGYSEL-LKVSPNFQIAAAFGNVHGVYKPGNV Schizosaccharomyces_pombe -NSHVSHTELYTQPEDIWDVYREL-SSVTPYFSIAAAFGNVHGVYKPGNV Saccharomyces_cerevisiae -NENADKEDLYTKPEQVYNVYKAL-HPISPNFSIAAAFGNCHGLY-AGDI Neurospora_crassa -NSEVDNASLYTQPEDIWQIEEDS-RPISPYFSIGAGFGNVHGVYAPGNV Mycobacterium_leprae -GEIN--EKLYTTPKDFVKTIDALGAGEHGKYLLAATFGNVHGVYKPGNV Streptomyces_galbus -HEIN--DSLYTTVDDAIRTAEALGLGEKGRYLLAASFGNVHGVYKPGNV : :. *. ** Helicobacter_pylori ------------PKLDFERLQEVKR-LTNIPLVLHGASAIPDNVRKSYLD Thermotoga_maritima ------------AQLDFERLKKVKE-YTQIPLVLHGASMVPQDIVKLANE Deinococcus_radiodurans ------------PFIDQARIKKIGE-LLSIPLVAHGSSGVPAEIVQRLRA Treponema_pallidum QCTRNADGVLIPPPLRFDILAEIEKRIPGFPIVLHGASSVPVEYVREVER Trichomonas_vaginalis ----------TKAEIRLDILHEIEKKLPGFPIVLHGSSSIPQEYVEMVNK Rhizobium_meliloti ---------PTGEVLAMDVIEKIHERLPDTHIVMHGSSSVPQEWQDVFNA Rhodobacter_sphaeroides ---------PDGEILAMSVIEAIHKKLPDTHLVMHGSSSVPQELQDIINA Caulobacter_crescentus ---------PDGDVLAMNVIEEIHRRLPNTHLVMHGSSSVPQDLQDIINQ Pseudomonas_stutzeri ---------PTGDTLSIQRIKEIHARIPDTHLVMHGSSSVPQEWLKIINE Neisseria_meningitidis ---------PTGDVLRIDRIKEIHQALPNTHIVMHGSSSVPQEWLKVINE Alcaligenes_eutrophus ---------PTGDILAMDRIREIHEQIPDTHLVMHGSSSVPQEWLEIIRQ Xanthobacter_flavus ---------PTGDILAIDRIKAIHQRIPTTHLVMHGSSSVPQELLEEIRT Nostoc_commune ---------PTGEILAISRIEEIHRRLPNTHLVMHGSSSVPEDLLALINQ Synechocystis_sp. ---------PTGEVLAISRIEEIHRLLPNTHLVMHGSSSVPQEWIDMINE Cyanophora_paradoxa ---------PDGAILRIDRIREINQAVPNTHLVMHGSSSVPEDLLALINA Giardia_lamblia ---------SD-IRLAIDRVKTISD-LTGIPLVMHGSSSVPKDVKDMINK Bacillus_subtilis --------------LGFKEMEEIGK-STGLPLVLHGGT------------ Mycoplasma_pneumoniae G-------------LNYELIEAIAK-ATNLPLVLHGGS------------ Escherichia_coli V-------------LTPTILRDSQEYVSKKHNLP--HNSLNFVFHG---- Haemophilus_influenzae K-------------LKPSILGESQEFVSKERNLP--AKPINFVFHG---- Campylobacter_jejuni S-------------LQPEILKNSQKFVKDKFALNS-DKPINFVFHG---- Borrelia_burgdorferi K-------------LTPKVLKDGQDYVISKTGVNM-AKPVSYVFHG---- Schizosaccharomyces_pombe K-------------LQPALLGQHQAYVKEQLKTTN-DKPVFFVFHG---- Saccharomyces_cerevisiae A-------------LRPEILAEHQKYTREQVGCKE-EKPLFLVFHG---- Neurospora_crassa K-------------LHPDLLGKQQAYVPEKLGGKD-KKPFFFVFHG---- Mycobacterium_leprae K-------------LRPDILAEGQKVAAAKLSQSEGSKPFDFVFHG---- Streptomyces_galbus V-------------LRPELLKELNEGVAARFGKES---PFDFVFHG---- : : . . Helicobacter_pylori AGGDLKGSKGVPFEFLQESVKGGINKVNTDTDLRIAFIAEVRKVANEDK- Thermotoga_maritima YGAELSGAKGVPEDMLKKAIELGINKINTDTDLRITFVAYLRKVLSEDK- Deinococcus_radiodurans AGGEIGDAAGIADEDLTEAAQYGIAKVNVDTDLRLASTVGIREVLKATP- Treponema_pallidum YGGNLPDSVGIPEEQLRKAAKSAVCKVNIDSDGRLAMTAAIRRVLTTKV- Trichomonas_vaginalis YGGHMPEAVGIPEHQLREASKSAVCKINIDSDGRMVMTGTIRRLFVEHP- Rhizobium_meliloti HGGEMRETYGVPVEEIVRGIRFGVRKVNIDTDLRLAAAAAFRRVADTSR- Rhodobacter_sphaeroides FGGAMPQTFGVPVEEIVRGIKMGVRKVNIDTDCRMAMTGQFRRIAQQTP- Caulobacter_crescentus YGGEMPQTWGVPVEEIQRGIKHGVRKINVDTDNRMAITGAIRKLLVEKP- Pseudomonas_stutzeri YGGEIGETYGVPVEEIVEGIKYGVRKVNIDTDLRLASTGAIREFLAKNP- Neisseria_meningitidis YGGNIGETYGVPVEEIVEGIKHGVRKVNIDTDLRLASTGAVRRYLAENP- Alcaligenes_eutrophus YGGDIKETYGVPVEEILRGIKMGVRKVNIDTDIRLAMTGAIRKSLSDDR- Xanthobacter_flavus YGGDIKETYGVPVEEIQEGIRYGVRKVNIDTDIRLAMTAAIRRVGAKNK- Nostoc_commune YGGAIPETYGVPVEEIQKGIKSGVRKVNIDTDNRLAITAAVREACAKKP- Synechocystis_sp. FGGAIPETYGVPVEEIQKGIKSGVRKVNIDTDNRLAITAAFREAAAKDP- Cyanophora_paradoxa NGGNIPETYGVPVEEIQAGIKAGVRKVNIDTDCRLAISAAVREALVKDT- Giardia_lamblia YGGKMPDAVGVPIESIVHAIGEGVCKINVDSDSRMAMTGAIRKVFVEHP- Bacillus_subtilis ---------GIPTADIKKSISLGTAKINVNTENQISSAKAVRETLAAKP- Mycoplasma_pneumoniae ---------GIPEADVKKAIGLGISKLNINTECQLAFAKAIREYVEAKKD Escherichia_coli -------GSGSTAQEIKDSVSYGVVKMNIDTDTQWATWEGVLNYYKANEA Haemophilus_influenzae -------GSGSSREEIREAIGYGAIKMNIDTDTQWASWNGILNFYKANEA Campylobacter_jejuni -------GSGSELKDIKNAVSYGVIKMNIDTDTQWAFWDGVREYELKNRA Borrelia_burgdorferi -------GSGSTIDEINEALSYGVVKMNIDTDTQWAAWEGVLNYYKKNES Schizosaccharomyces_pombe -------GSGSSVNEFRTGIKCGVVKVNIDTDTQFAYVEGVRDYVLKYKD Saccharomyces_cerevisiae -------GSGSTVQEFHTGIDNGVVKVNLDTDCQYAYLTGIRDYVLNKKD Neurospora_crassa -------GSGSSKEEYREAISNGVVKVNVDTDLQWSYLVGIRDYILNNID Mycobacterium_leprae -------GSGSEKSEIEEALRYGVVKMNVDTDTQYAFTRPVSGHMFTNYD Streptomyces_galbus -------GSGSSEEEIRTALENGVVKMNLDTDTQYAFTRPVAGHMFANYD .. * . . *:* ::: : . Helicobacter_pylori -----------------SQFDLRKFFSPAQLALKNVVKER-MKLLGSANK Thermotoga_maritima -----------------SQIDPRKIFKPVFEQVKEIVKER-IRIFGSSGK Deinococcus_radiodurans -----------------KEFDPRKIFGPARDVMSQIVEHK-MGVLGSVGK Treponema_pallidum -----------------DEFDPRKYLGPARDELKKLYMHKNKEVLGSAGR Trichomonas_vaginalis -----------------DWFDPRQYLGEARTKLTEMYMRKDQEVLGCAGH Rhizobium_meliloti -----------------TEFDPRKFLKPAMDAMSAVCKAR-FEAFGTAGN Rhodobacter_sphaeroides -----------------SEFDPRKFLKPAMDAMRDLCKQR-LEAFGTAGQ Caulobacter_crescentus -----------------GEFDPRAYLKPAKEAMRKVCQAR-FVEFGSAGH Pseudomonas_stutzeri -----------------SEFDPRKYFAKTVAAMRDICIAR-YEAFGTAGN Neisseria_meningitidis -----------------SDFDPRKYLSKTIEAMKQICLDR-YLAFGCEGQ Alcaligenes_eutrophus -----------------SEFDPRKALLAAKKGARSVVKLR-FEAFGCAGQ Xanthobacter_flavus -----------------SEFDPRKFMAAAMEEAKKVCIAR-FEAFGSAGK Nostoc_commune -----------------EEFDPRHFLKPSITYMQKVCAER-YQQFGTAGN Synechocystis_sp. -----------------KNFDPRHFLKPSIKYMKQVCADR-YQQFWTAGN Cyanophora_paradoxa -----------------KEFDPRHS-QASMKYMQKVCEDR-YVQFNAAGN Giardia_lamblia -----------------EKFDPRDYLGPGRDAITEMLIPK-IKAFGSAGH Bacillus_subtilis -----------------DEYDPRKYLGPAREAIKETVIGK-MREFGSSNQ Mycoplasma_pneumoniae ------------LDTHNKGYDPRKLLKSPTQAIVDCCLEK-MQLCGSTNK Escherichia_coli YLQGQLGNPKGEDQPNKKYYDPRVWLRAGQTSMIARLEKA-FQELNAIDV Haemophilus_influenzae YLQGQLGNPEGPDAPNKKYYDPRVWLRKMEESMSKRLEQS-FEDLNCVDV Campylobacter_jejuni YLQGQIGNPEGDDKPNKKYYDPRVWLRSGEESMIKRLEIA-FEDLNCINK Borrelia_burgdorferi RLQGQLGDGKDIDIPNKKFYDPRVWLREAEVSMKDRVKIA-CKNLNNINR Schizosaccharomyces_pombe YLMTPVGNPEGADKPNKKKFDPRVWIHEGEKTMTKRVLTA-LEDFYTVNT Saccharomyces_cerevisiae YIMSPVGNPEGPEKPNKKFFDPRVWVREGEKTMGAKITKS-LETFRTTNT Neurospora_crassa YLRSQVGNPEGPNKPNKKKYDPRVWIREGEKTMKARVEEG-PQGPSNTTV Mycobacterium_leprae GVLKVDG-----DVGNKKVYDPRSYLKKAEASMTERVLEA-CNDLRCAGK Streptomyces_galbus GVLKVDG-----EVGNKKAYDPRTWGKLAEASMAARVVEA-TQHLRSAGN * * Helicobacter_pylori I---------------------------------- Thermotoga_maritima A---------------------------------- Deinococcus_radiodurans A---------------------------------- Treponema_pallidum A---------------------------------- Trichomonas_vaginalis AFD-------------------------------- Rhizobium_meliloti ASRIKVVPMAEMARRYASGSLKPQAKRAEAA---- Rhodobacter_sphaeroides AGKIRIIPMDDMAKRYASGALAPKTA--------- Caulobacter_crescentus ADKIKPMSTATMAKRYASGELHAKFGASAAKAAAE Pseudomonas_stutzeri ASKIKPISLEGMFQRYASGELDPKIN--------- Neisseria_meningitidis AGKIKPVSLEKMANRYAKGELNQIVK--------- Alcaligenes_eutrophus ASRIKPVPLERVAKLYS------------------ Xanthobacter_flavus AEKIRAIELDEMAKRYASGELAQVVH--------- Nostoc_commune ASKIKQISLEDFAAKYAKGELNVVTKAAAKV---- Synechocystis_sp. ASKIKQLTLDDYAAKYAKGELTATSRTSVAV---- Cyanophora_paradoxa ADKIKAVDLDTMAKKFYATA--------------- Giardia_lamblia AGDYKVVSLEEAKAWYK------------------ Bacillus_subtilis A---------------------------------- Mycoplasma_pneumoniae A---------------------------------- Escherichia_coli L---------------------------------- Haemophilus_influenzae L---------------------------------- Campylobacter_jejuni N---------------------------------- Borrelia_burgdorferi N---------------------------------- Schizosaccharomyces_pombe L---------------------------------- Saccharomyces_cerevisiae L---------------------------------- Neurospora_crassa TV--------------------------------- Mycobacterium_leprae SVAAS------------------------------ Streptomyces_galbus KIK-------------------------------- : :::.