Supporting Information for Ritter et al. (2002) Proc. Natl. Acad. Sci. USA 99 (11), 74557460. (10.1073/pnas.102185799)
Table 2. Genes up-regulated at least 3-fold as hemangiomas progress toward involution
Common name | GenBank no. | Proliferating | Plateau | Involuting |
Prolactin-induced protein | Y10179- | 0.0 | 0.0 | 11.3 |
Prolactin-induced protein | HG1763-HT1780 | 0.0 | 0.0 | 9.3 |
Mammaglobin | U33147 | 0.0 | 0.0 | 11.7 |
Keratin 5 | M21389 | 0.1 | 0.1 | 22.0 |
Lipophilin B | AW015055 | 0.0 | 0.0 | 3.5 |
Cytokeratin 15 | X07696 | 0.1 | 0.1 | 12.5 |
Desmoplakin I | AL031058 | 0.1 | 0.4 | 11.9 |
Zn- a 2-glycoprotein | X59766 | 0.0 | 0.1 | 2.9 |
Keratin | J00124 | 0.4 | 0.9 | 44.5 |
Keratin type II | L42611 | 0.1 | 0.5 | 7.6 |
Alcohol dehydrogenase | M12963 | 0.2 | 0.6 | 8.8 |
Aquaporin 3 | N74607 | 0.3 | 0.9 | 9.8 |
Periplakin | AF001691 | 0.3 | 3.0 | 9.6 |
INHBB | M31682 | 0.1 | 0.6 | 3.5 |
Frizzled related protein | AF056087 | 0.4 | 0.5 | 9.0 |
Ataxia-telangiectasia group D-associated protein | L24203 | 0.3 | 0.6 | 6.1 |
Stratifin | X57348 | 1.1 | 2.3 | 14.5 |
Defensin, b 1 | AI309115 | 0.6 | 0.6 | 5.3 |
Complement factor H | X07523 | 1.4 | 4.6 | 13.4 |
Retinol-binding protein 4, interstitial | X00129 | 0.2 | 0.2 | 1.6 |
CD9 | M38690 | 1.3 | 3.9 | 11.7 |
Adipsin | M84526 | 3.1 | 8.0 | 26.3 |
Stratifin | X57348 | 3.1 | 6.2 | 26.5 |
Metallothionein 1L | AA224832 | 1.0 | 1.6 | 8.1 |
Na,K-ATPase b subunit | U16799 | 1.6 | 1.7 | 12.5 |
Gastrointestinal tumor-associated antigen | J04152 | 1.0 | 1.8 | 7.9 |
Intercrine- a (hIRH) | U19495 | 1.1 | 2.4 | 8.7 |
Hepatic dihydrodiol dehydrogenase | U05861 | 1.2 | 3.1 | 9.1 |
Long-chain acyl-CoA synthetase | D10040 | 0.7 | 0.9 | 5.0 |
Cytokeratin 10 | X14487 | 3.1 | 7.4 | 23.0 |
Creatine kinase B | X15334 | 0.9 | 1.1 | 6.2 |
Apolipoprotein D | J02611 | 3.6 | 4.8 | 23.2 |
Semaphorin 3C | AB000220 | 0.6 | 0.5 | 3.8 |
RNase 4 | D37931 | 0.7 | 1.2 | 4.2 |
Complement cytolysis inhibitor | M25915 | 5.0 | 15.9 | 27.8 |
Perilipin | AB005293 | 0.9 | 0.9 | 5.1 |
NMB | X76534 | 1.8 | 3.3 | 9.3 |
Complement component 1 | J04080 | 2.9 | 6.3 | 14.1 |
Syndecan-1 | Z48199 | 1.5 | 2.2 | 7.0 |
Tyr phosphatase, receptor type, f polypeptide | Y00815 | 1.2 | 1.6 | 5.8 |
Mitochondrial aldehyde dehydrogenase I | X05409 | 3.2 | 5.1 | 14.8 |
Breast carcinoma fatty acid synthase | U29344 | 1.0 | 0.3 | 4.5 |
Glypican 3 | U50410 | 1.1 | 1.7 | 5.2 |
Neuralin 1 | AL049176 | 0.6 | 0.4 | 2.9 |
Fibulin 1 | U01244 | 1.2 | 1.5 | 5.3 |
Cathepsin G | M16117 | 1.2 | 1.8 | 5.2 |
p78 | M33882 | 0.9 | 1.6 | 4.0 |
AQP-1 | U41518 | 2.0 | 9.6 | 8.6 |
S100A4 | W72186 | 2.4 | 4.6 | 10.1 |
Tenascin XB | U89337 | 1.0 | 2.3 | 4.0 |
SDF1b | L36033 | 1.4 | 5.2 | 5.5 |
Factor H homologue | M65292 | 2.0 | 3.8 | 8.1 |
ERF-2 | X78992 | 2.9 | 9.9 | 11.2 |
SCYA14 | AI720438 | 1.4 | 7.2 | 5.4 |
Galectin-3 | AB006780 | 3.2 | 6.8 | 11.7 |
DPT | AL049798 | 1.5 | 2.5 | 5.2 |
Dermatopontin | Z22865 | 1.1 | 1.7 | 4.0 |
Fibulin-2 | X82494 | 1.3 | 2.8 | 4.4 |
DARC | X85785 | 1.2 | 3.4 | 4.0 |
P8 (nuclear protein 1) | AI557295 | 1.6 | 2.2 | 5.4 |
G0S2 | M69199 | 0.6 | 0.7 | 2.0 |
ENPP2 | L35594 | 1.6 | 3.1 | 5.4 |
CBX7 | AL031846 | 1.2 | 2.2 | 4.1 |
MYH11 | AF001548 | 1.2 | 1.1 | 3.8 |
GAS1 | L13698 | 2.2 | 2.5 | 7.1 |
IFN-inducible 56-kDa protein | M24594 | 1.3 | 1.8 | 4.1 |
MEGF5 | AB011538 | 1.2 | 1.1 | 3.8 |
RTP | D87953 | 2.1 | 4.6 | 6.4 |
Values represent fold increase over median expression.