Supporting Information for Ritter et al. (2002) Proc. Natl. Acad. Sci. USA 99 (11), 7455–7460. (10.1073/pnas.102185799)

Table 2. Genes up-regulated at least 3-fold as hemangiomas progress toward involution

Common name

GenBank no.

Proliferating

Plateau

Involuting

Prolactin-induced protein

Y10179-

0.0

0.0

11.3

Prolactin-induced protein

HG1763-HT1780

0.0

0.0

9.3

Mammaglobin

U33147

0.0

0.0

11.7

Keratin 5

M21389

0.1

0.1

22.0

Lipophilin B

AW015055

0.0

0.0

3.5

Cytokeratin 15

X07696

0.1

0.1

12.5

Desmoplakin I

AL031058

0.1

0.4

11.9

Zn-

a 2-glycoprotein

X59766

0.0

0.1

2.9

Keratin

J00124

0.4

0.9

44.5

Keratin type II

L42611

0.1

0.5

7.6

Alcohol dehydrogenase

M12963

0.2

0.6

8.8

Aquaporin 3

N74607

0.3

0.9

9.8

Periplakin

AF001691

0.3

3.0

9.6

INHBB

M31682

0.1

0.6

3.5

Frizzled related protein

AF056087

0.4

0.5

9.0

Ataxia-telangiectasia group D-associated protein

L24203

0.3

0.6

6.1

Stratifin

X57348

1.1

2.3

14.5

Defensin,

b 1

AI309115

0.6

0.6

5.3

Complement factor H

X07523

1.4

4.6

13.4

Retinol-binding protein 4, interstitial

X00129

0.2

0.2

1.6

CD9

M38690

1.3

3.9

11.7

Adipsin

M84526

3.1

8.0

26.3

Stratifin

X57348

3.1

6.2

26.5

Metallothionein 1L

AA224832

1.0

1.6

8.1

Na,K-ATPase

b subunit

U16799

1.6

1.7

12.5

Gastrointestinal tumor-associated antigen

J04152

1.0

1.8

7.9

Intercrine-

a (hIRH)

U19495

1.1

2.4

8.7

Hepatic dihydrodiol dehydrogenase

U05861

1.2

3.1

9.1

Long-chain acyl-CoA synthetase

D10040

0.7

0.9

5.0

Cytokeratin 10

X14487

3.1

7.4

23.0

Creatine kinase B

X15334

0.9

1.1

6.2

Apolipoprotein D

J02611

3.6

4.8

23.2

Semaphorin 3C

AB000220

0.6

0.5

3.8

RNase 4

D37931

0.7

1.2

4.2

Complement cytolysis inhibitor

M25915

5.0

15.9

27.8

Perilipin

AB005293

0.9

0.9

5.1

NMB

X76534

1.8

3.3

9.3

Complement component 1

J04080

2.9

6.3

14.1

Syndecan-1

Z48199

1.5

2.2

7.0

Tyr phosphatase, receptor type, f polypeptide

Y00815

1.2

1.6

5.8

Mitochondrial aldehyde dehydrogenase I

X05409

3.2

5.1

14.8

Breast carcinoma fatty acid synthase

U29344

1.0

0.3

4.5

Glypican 3

U50410

1.1

1.7

5.2

Neuralin 1

AL049176

0.6

0.4

2.9

Fibulin 1

U01244

1.2

1.5

5.3

Cathepsin G

M16117

1.2

1.8

5.2

p78

M33882

0.9

1.6

4.0

AQP-1

U41518

2.0

9.6

8.6

S100A4

W72186

2.4

4.6

10.1

Tenascin XB

U89337

1.0

2.3

4.0

SDF1b

L36033

1.4

5.2

5.5

Factor H homologue

M65292

2.0

3.8

8.1

ERF-2

X78992

2.9

9.9

11.2

SCYA14

AI720438

1.4

7.2

5.4

Galectin-3

AB006780

3.2

6.8

11.7

DPT

AL049798

1.5

2.5

5.2

Dermatopontin

Z22865

1.1

1.7

4.0

Fibulin-2

X82494

1.3

2.8

4.4

DARC

X85785

1.2

3.4

4.0

P8 (nuclear protein 1)

AI557295

1.6

2.2

5.4

G0S2

M69199

0.6

0.7

2.0

ENPP2

L35594

1.6

3.1

5.4

CBX7

AL031846

1.2

2.2

4.1

MYH11

AF001548

1.2

1.1

3.8

GAS1

L13698

2.2

2.5

7.1

IFN-inducible 56-kDa protein

M24594

1.3

1.8

4.1

MEGF5

AB011538

1.2

1.1

3.8

RTP

D87953

2.1

4.6

6.4

Values represent fold increase over median expression.