Matsuoka et al. 10.1073/pnas.0504908102. |
Fig. 6. Social interaction (Left) and aggression (Right) of male littermates born from Ptger1+/– parents. Social interaction and aggression in the presence of a juvenile conspecific male were measured for the indicated genotypes (n = 7, 10, and 4 for Ptger1+/+, Ptger1+/– and Ptger1–/– littermates, respectively). *, P < 0.05, **; P < 0.01 for the indicated comparisons; ***, P < 0.001 vs. both Ptger1+/– and wild-type littermates.
Fig. 7. Cliff avoidance of littermates born from Ptger1+/– parents. The cumulative frequency of jumping in littermates of the indicated genotypes was determined (n = 8, 17, and 7 for Ptger1+/+, Ptger1+/– and Ptger1–/– littermates, respectively). #, P < 0.05 vs. Ptger1+/–; *, P < 0.05; ***, P < 0.001 vs. wild type.
Fig. 8. Behavioral analyses of Ptger1–/– mice. Wild-type or Ptger1–/– mice (n = 12 and 11, respectively) were subjected to the light/dark-box test (A), the elevated- plus-maze test (B), and the Y-maze test (C). The total number of entries into and the total duration spent in either the light compartment (A) or the open arms (B) were measured. The total number of arm entries and alternation behavior were measured in (C).
Movie 1. Representative behavior of male wild-type (Right) or Ptger1–/– (Left) mice confronted with a juvenile conspecific male.
Movie 2. Representative behaviors of male wild-type (Left) or Ptger1–/– (Right) mice injected with LPS and confronted with a juvenile conspecific male 1 h later.
Movie 3. Representative jumping behavior of a Ptger1–/– mouse (impaired cliff avoidance).